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https://www.readbyqxmd.com/read/28820681/efficacy-safety-and-cost-effectiveness-of-thermotherapy-in-the-treatment-of-leishmania-donovani-induced-cutaneous-leishmaniasis-a-randomized-controlled-clinical-trial
#1
Wardha F Refai, Nayani P Madarasingha, Buthsiri Sumanasena, Sudath Weerasingha, Amala De Silva, Rohini Fernandopulle, Abhay R Satoskar, Nadira D Karunaweera
Leishmania donovani causes cutaneous leishmaniasis (CL) in Sri Lanka. Standard treatment is multiple, painful doses of intralesional sodium stibogluconate (IL-SSG). Treatment failures are increasingly reported, hence the need to investigate alternatives. Efficacy, safety, and cost-effectiveness of thermotherapy were assessed for the first time for L. donovani CL. A single blinded noninferiority randomized controlled trial was conducted on new laboratory-confirmed CL patients with single lesions (N = 213). Selected patients were randomly assigned to 1) test group (N = 98; single session of radiofrequency-induced heat therapy (RFHT) given at 50°C for 30 seconds) and 2) control group (N = 115; 1-3 mL IL-SSG given weekly, until cure/10 doses)...
August 14, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28819902/ablation-therapy-for-barrett-s-esophagus-new-rules-for-changing-times
#2
REVIEW
Nour Hamade, Prateek Sharma
PURPOSE OF REVIEW: In this review, we discuss different endoscopic techniques in the eradication of Barrett's esophagus (BE) as well as some controversies in the field of treatment. RECENT FINDINGS: Patients with T1a esophageal adenocarcinoma and BE of high-grade dysplasia should undergo endoscopic ablative therapy. The most studied technique to date is radiofrequency ablation. It can be combined with endoscopic mucosal resection in cases containing nodular and flat lesions...
August 17, 2017: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/28819609/combined-fluoroscopic-and-arthroscopic-detection-and-removal-of-a-foreign-body-lost-during-elective-shoulder-arthroscopy-a-case-report
#3
Uli Schmiddem, N Hawi, E M Suero, R Meller
INTRODUCTION: We report a case of a lost metal platelet from a radiofrequency ablation probe (VAPR VUE Radiofrequency System, Cool Pulse 90, DePuy, Synthes, Switzerland) in the shoulder joint during elective arthroscopic cuff repair. To the best of our knowledge, this kind of an incident during elective arthroscopy has not been described in the literature so far. In addition, we present an algorithm on how to deal with such an incident. CASE REPORT: A 69-year-old woman underwent an arthroscopic subacromial decompression and rotator cuff repair for a torn supraspinatus tendon...
March 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28818088/assessment-of-the-effect-of-left-atrial-cryoablation-enhanced-by-ganglionated-plexi-ablation-in-the-treatment-of-atrial-fibrillation-in-patients-undergoing-open-heart-surgery
#4
Jiří Bárta, Radim Brát
BACKGROUND: The aim of our study was to investigate, whether enhancement of left atrial cryoablation by ablation of the autonomic nervous system of left atrium leads to influencing the outcomes of surgical treatment of atrial fibrillation in patients with structural heart disease undergoing open-heart surgery. METHODS: The observed patient file consisted of 100 patients, who have undergone a combined open-heart surgery at our department between July 2012 and December 2014...
August 17, 2017: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28816408/endoscopic-treatment-of-barrett-s-esophagus-what-can-we-learn-from-the-western-perspective
#5
REVIEW
Yuto Shimamura, Yugo Iwaya, Kenichi Goda, Christopher W Teshima
The incidence of Barrett's esophagus (BE) related neoplasia in Western countries has increased in the past several decades, and even in Eastern countries, it appears to be increasing. Endoscopic therapies are the first-line treatment for BE-related neoplasia, however there is still no standardized treatment strategy. Most of the data have been published from Western countries where the ultimate goal of treatment is complete eradication of BE mucosa removing subtle synchronous lesions and preventing metachronous neoplasia...
August 17, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28815189/a-case-of-pulmonary-vein-thrombosis-associated-with-treatment-of-omalizumab
#6
Sandhya Narukonda, Nagadarshini Ramagiri Vinod, Medha Joshi
Pulmonary vein thrombosis (PVT) is a challenging diagnosis and has been described in association with or as a complication of pulmonary tumors, lung surgeries, atrial myxoma, and after radiofrequency catheter ablation for atrial fibrillation. There are not many reported cases of PVT associated with medication use. We present a case of a 53-year-old male with a history of severe persistent asthma on omalizumab, who presented with shortness of breath and was found to have PVT on computed tomography scan of the chest...
July 2017: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/28812002/image-guided-thermal-ablation-with-mr-based-thermometry
#7
REVIEW
Mingming Zhu, Ziqi Sun, Chin K Ng
Thermal ablation techniques such as radiofrequency, microwave, high intensity focused ultrasound (HIFU) and laser have been used as minimally invasive strategies for the treatment of variety of cancers. MR thermometry methods are readily available for monitoring thermal distribution and deposition in real time, leading to decrease of incidents of normal tissue damage around targeted lesion. HIFU and laser-induced thermal therapy (LITT) are the two widely accepted tumor ablation techniques because of their compatibility with MR systems...
June 2017: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/28811965/adjuvant-immunotherapy-with-autologous-dendritic-cells-for-hepatocellular-carcinoma-randomized-phase-ii-study
#8
Jeong-Hoon Lee, Won Young Tak, Yoon Lee, Min-Kyu Heo, Jae-Sung Song, Hak-Yeop Kim, Soo Young Park, Si Hyun Bae, Joon Hyeok Lee, Jeong Heo, Ki-Hwan Kim, Yong-Soo Bae, Yoon Jun Kim
Our previous phase I/IIA study showed that autologous dendritic cells (DCs) pulsed with tumor-associated antigens are well tolerated in patients with hepatocellular carcinoma (HCC). In this randomized, multicenter, open-label, phase II trial, we investigated the efficacy and safety of this DC-based adjuvant immunotherapy with 156 patients, who treated for HCC with no evidence of residual tumor after standard treatment modalities. Patients were randomly assigned to immunotherapy (n = 77; injection of 3 × 10(7) DC cells, six times over 14 weeks) or control (n = 79; no treatment)...
2017: Oncoimmunology
https://www.readbyqxmd.com/read/28810261/comparative-evaluation-of-magnetic-resonance-guided-focused-ultrasound-surgery-for-essential-tremor
#9
Minsoo Kim, Na Young Jung, Chang Kyu Park, Won Seok Chang, Hyun Ho Jung, Jin Woo Chang
BACKGROUND: Treatment options for patients with drug-resistant essential tremor (ET) are limited. Magnetic resonance-guided focused ultrasound surgery (MRgFUS) is an emerging technique to treat refractory ET. OBJECTIVES: To present MRgFUS as an alternative to radiofrequency (RF) thalamotomy or deep brain stimulation (DBS) for ET treatment. METHODS: We retrospectively analyzed 59 patients who underwent unilateral surgery for drug-resistant ET...
August 16, 2017: Stereotactic and Functional Neurosurgery
https://www.readbyqxmd.com/read/28809890/tunable-photonic-radiofrequency-filter-with-complementary-bandpass-and-bandstop-responses
#10
Peixuan Li, Wei Pan, Xihua Zou, Lianshan Yan, Yan Pan
A photonic radiofrequency (RF) filter with two complementary bandpass and bandstop responses that is capable of simultaneously providing a single transmission channel at one port and a notch rejection channel at the other port is proposed. An integrated polarization division-multiplexing Mach-Zehnder modulator and the in-fiber stimulated Brillouin scattering effect are used to control the amplitudes and phases of the RF modulation sidebands along two orthogonal states of polarization to generate two complementary bandpass and bandstop responses at two output ports, respectively...
August 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28809734/wait-time-for-curative-intent-radio-frequency-ablation-is-associated-with-increased-mortality-in-patients-with-early-stage-hepatocellular-carcinoma
#11
Mayur Brahmania, Osman Ahmed, Melissa Kelley, David Wong, Matthew Kowgier, Korosh Khalili, Rob Beecroft, Eberhard L Renner, Hemant Shah, Jordan Feld, Harry L A Janssen, Morris Sherman
INTRODUCTION: Radiofrequency ablation (RFA) is a recommended curative intent treatment option for patients with early stage hepatocellular carcinoma (HCC). We investigated if wait times for RFA were associated with residual tumor, tumor recurrence, need for liver transplantation, or death. MATERIAL AND METHODS: We conducted a retrospective study of patients diagnosed with HCC between January 2010 and December 2013 presenting to University Health Network (UHN) in Toronto, Canada...
August 8, 2017: Annals of Hepatology
https://www.readbyqxmd.com/read/28809670/cardio-pulmonary-stethoscope-clinical-validation-with-heart-failure-and-hemodialysis-patients
#12
Magdy F Iskander, Todd B Seto, Ruthsenne Rg Perron, Eunjung Lim, Farhan Qazi
OBJECTIVE: The purpose of this study is to evaluate the accuracy of a noninvasive radiofrequency-based device, the Cardio-Pulmonary Stethoscope (CPS), to monitor heart and respiration rates and detect changes in lung water content in human experiments and clinical trials. METHODS: Three human populations (healthy subjects (n=4), heart failure (n=12) and hemodialysis (n=13) patients) were enrolled in this study. The study was conducted at the University of Hawaii and The Queen's Medical Center in Honolulu, HI...
August 14, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28807894/advances-in-the-diagnosis-and-management-of-neck-pain
#13
REVIEW
Steven P Cohen, W Michael Hooten
Neck pain imposes a considerable personal and socioeconomic burden-it is one of the top five chronic pain conditions in terms of prevalence and years lost to disability-yet it receives a fraction of the research funding given to low back pain. Although most acute episodes resolve spontaneously, more than a third of affected people still have low grade symptoms or recurrences more than one year later, with genetics and psychosocial factors being risk factors for persistence. Nearly half of people with chronic neck pain have mixed neuropathic-nociceptive symptoms or predominantly neuropathic symptoms...
August 14, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28807571/radiofrequency-ablation-for-osteoid-osteoma-recurrence-rates-and-predictive-factors
#14
David W Shields, Sadaf Sohrabi, Evan O Crane, Chris Nicholas, Ashish Mahendra
BACKGROUND AND PURPOSE: Osteoid osteoma is an infrequent but debilitating benign bone lesion which can be successfully managed by percutaneous radiofrequency ablation (RFA). There are few studies investigating the efficacy and follow-up of this treatment. An arbitrary upper limit of 15 mm has been used to differentiate between osteoid osteoma and osteoblastoma with surgery used for lesions above this limit. We aimed to analyse the cases identified from our prospectively maintained database over a ten year period since adoption of this technique in our unit...
August 11, 2017: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://www.readbyqxmd.com/read/28807570/albumin-bilirubin-grade-predicts-the-outcomes-of-liver-resection-versus-radiofrequency-ablation-for-very-early-early-stage-of-hepatocellular-carcinoma
#15
Charing Ching-Ning Chong, Anthony Wing-Hung Chan, John Wong, Cheuk-Man Chu, Stephen Lam Chan, Kit-Fai Lee, Simon Chun-Ho Yu, Ka-Fai To, Philip Johnson, Paul Bo-San Lai
BACKGROUND AND PURPOSE: Whether liver resection or ablation should be the first-line treatment for very early/early hepatocellular carcinoma (HCC) in patients who are candidates for both remains controversial. The aim of this study was to determine if the newly-developed Albumin-Bilirubin (ALBI) grade might help in treatment selections and to evaluate the survival of patients treated with liver resection and radiofrequency ablation (RFA). METHODS: Patients with BCLC stage 0/A HCC who were treated with curative liver resection and RFA from 2003 to 2013 were included...
August 11, 2017: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://www.readbyqxmd.com/read/28807449/non-invasive-intra-cardiac-pressure-measurements-using-subharmonic-aided-pressure-estimation-proof-of-concept-in-humans
#16
Jaydev K Dave, Sushmita V Kulkarni, Purva P Pangaonkar, Maria Stanczak, Maureen E McDonald, Ira S Cohen, Praveen Mehrotra, Michael P Savage, Paul Walinsky, Nicholas J Ruggiero, David L Fischman, David Ogilby, Carolyn VanWhy, Matthew Lombardi, Flemming Forsberg
This study evaluated the feasibility of employing non-invasive intra-cardiac pressure estimation using subharmonic signals from ultrasound contrast agents in humans. This institutional review board-approved proof-of-concept study included 15 consenting patients scheduled for left and right heart catheterization. During the catheterization procedure, Definity was infused intra-venously at 4-10 mL/min. Ultrasound scanning was performed with a Sonix RP using pulse inversion, three incident acoustic output levels and 2...
August 11, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28807250/a-systematic-review-on-radiofrequency-assisted-laparoscopic-liver-resection-challenges-and-window-to-excel
#17
REVIEW
Isabella Reccia, Jayant Kumar, Tomokazu Kusano, Artur Zanellato, Ahmed Draz, Duncan Spalding, Nagy Habib, Madhava Pai
Laparoscopic liver resection has progressively gained acceptance as a safe and effective procedure in the treatment of benign and malignant liver neoplasms. However, blood loss remains the major challenge in liver surgery. Several techniques and devices have been introduced in liver surgery in order to minimize intraoperative haemorrhage during parenchymal transection. Radiofrequency (RF)-assisted liver resection has been shown to be an effective method to minimize bleeding in open and laparoscopic liver resection...
September 2017: Surgical Oncology
https://www.readbyqxmd.com/read/28807242/efficacy-and-safety-of-combination-therapy-of-chemoembolization-and-radiofrequency-ablation-with-different-time-intervals-for-hepatocellular-carcinoma-patients
#18
Yue-Min Feng, Xing Wang, Le Wang, Xiao-Wen Ma, Hao Wu, Hao-Ran Bu, Xiao-Yu Xie, Jian-Ni Qi, Qiang Zhu
BACKGROUND AND OBJECTIVES: Combination of transcatheter arterial chemoembolization (TACE) and radiofrequency ablation (RFA) has become an effective alternative therapy for hepatocellular carcinoma (HCC). In clinical practice, the choice of time interval between TACE and RFA is a key point for curative effect, but optimal time interval is uncertain in guidelines. We aim to explore the optimal time interval for HCC patients of Child-Pugh classification A or B. METHODS: Two hundred and thirty-three HCC patients of Child A or B who had undergone TACE and RFA were enrolled and divided into seven groups according to different time intervals (1-7weeks)...
September 2017: Surgical Oncology
https://www.readbyqxmd.com/read/28807241/the-impact-of-radiofrequency-assisted-transection-on-local-hepatic-recurrence-after-resection-of-colorectal-liver-metastases
#19
R Quesada, A Moreno, I Poves, E Berjano, L Grande, F Burdío
Resection is the gold standard in the treatment of liver metastases from colorectal cancer. An internal cooled radiofrequency electrode was described to achieve tissue coagulation to a greater margin width. The aim of this study is to determinate if a RF-assisted transection device (RFAT) has any effect on local hepatic recurrence (LHER) compared to conventional technologies. A study population of 103 patients who had undergone a hepatic surgical resection was retrospectively analysed. Patients were classified into two groups according to the device used: a RF-assisted device (RFAT group; n = 45) and standard conventional devices (control group; n = 58)...
September 2017: Surgical Oncology
https://www.readbyqxmd.com/read/28806322/reduced-field-of-view-diffusion-weighted-magnetic-resonance-imaging-of-the-prostate-at-3-tesla-comparison-with-standard-echo-planar-imaging-technique-for-image-quality-and-tumor-assessment
#20
Tsutomu Tamada, Justin M Ream, Ankur M Doshi, Samir S Taneja, Andrew B Rosenkrantz
OBJECTIVE: The purpose of this study was to compare image quality and tumor assessment at prostate magnetic resonance imaging (MRI) between reduced field-of-view diffusion-weighted imaging (rFOV-DWI) and standard DWI (st-DWI). METHODS: A total of 49 patients undergoing prostate MRI and MRI/ultrasound fusion-targeted biopsy were included. Examinations included st-DWI (field of view [FOV], 200 × 200 mm) and rFOV-DWI (FOV, 140 × 64 mm) using a 2-dimensional (2D) spatially-selective radiofrequency pulse and parallel transmission...
August 12, 2017: Journal of Computer Assisted Tomography
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