keyword
MENU ▼
Read by QxMD icon Read
search

Juurlink

keyword
https://www.readbyqxmd.com/read/29762260/clinical-indications-associated-with-opioid-initiation-for-pain-management-in-ontario-canada-a-population-based-cohort-study
#1
Sachin V Pasricha, Mina Tadrous, Wayne Khuu, David N Juurlink, Muhammad M Mamdani, J Michael Paterson, Tara Gomes
Concerns over prescription opioids contributing to high levels of opioid use disorder and overdose have led policymakers and clinicians to seek means to reduce inappropriate and high-dose initial prescriptions. To inform such efforts, we sought to describe the clinical indications associated with opioid initiation and the characteristics of the initial prescriptions and patients through a retrospective population-based cohort study. Our cohort included Ontarians initiating prescription opioids for pain management between April 1, 2015, and March 31, 2016...
May 14, 2018: Pain
https://www.readbyqxmd.com/read/29697503/measuring-the-burden-of-opioid-related-mortality-in-ontario-canada
#2
Tara Gomes, Simon Greaves, Mina Tadrous, Muhammad M Mamdani, J Michael Paterson, David N Juurlink
No abstract text is available yet for this article.
April 25, 2018: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/29694284/publicly-funded-oral-chronic-hepatitis-b-treatment-patterns-in-ontario-over-16-years-an-ecologic-study
#3
Mina Tadrous, Mayur Brahmania, Diana Martins, Sandra Knowles, Harry L A Janssen, Muhammad M Mamdani, David N Juurlink, Tara Gomes
BACKGROUND: Reimbursement for the use of hepatitis B virus (HBV) treatments has not been previously reported for public payers. OBJECTIVE: To describe the number of users and total cost of HBV treatments over the last 16 years among residents of Ontario, Canada, who were covered by the public drug program. METHODS: We conducted a repeated cross-sectional study for HBV treatments reimbursed by the public drug program in Ontario from January 1, 2000, to December 31, 2015...
May 2018: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/29603206/critiquing-the-cdc-opioid-guideline-some-light-from-the-heat
#4
David N Juurlink
Released in 2016, the Centers for Disease Control and Prevention (CDC) Guideline for Prescribing Opioids for Chronic Pain has been met with both praise and criticism. In this issue of the Journal, two commentaries address the guideline's strengths and limitations. While the authors differ in their assessment of the guideline, they share a common objective: safer opioid prescribing. Followed carefully, the CDC guideline will facilitate this, but followed carelessly it has the potential to cause harm.
March 30, 2018: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29581101/catastrophic-drug-coverage-utilization-insights-from-the-ontario-trillium-drug-program
#5
Mina Tadrous, Simon Greaves, Diana Martins, Muhammad M Mamdani, David N Juurlink, Tara Gomes
BACKGROUND: Catastrophic drug coverage programs help those with high drug-costs to reduce the burden of out-of-pocket expenses. We set out to measure changes in utilization, spending and demographic profiles of people accessing Ontario's catastrophic drug program, the Trillium Drug Program. METHODS: We conducted a cross-sectional time-series analysis examining quarterly utilization and spending trends among medications reimbursed by the Trillium Drug Program in Ontario, Canada from Jan...
March 14, 2018: CMAJ Open
https://www.readbyqxmd.com/read/29519782/fluoroquinolones-and-the-aorta
#6
EDITORIAL
David N Juurlink
No abstract text is available yet for this article.
March 8, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29431112/argyria-caused-by-chronic-ingestion-of-silver
#7
Nathan A Bracey, Jonathan S Zipursky, David N Juurlink
No abstract text is available yet for this article.
February 5, 2018: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/29417932/stepped-surfaces
#8
Ludo Juurlink
No abstract text is available yet for this article.
March 7, 2018: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/29319477/publicly-funded-overactive-bladder-drug-treatment-patterns-in-ontario-over-15-years-an-ecologic-study
#9
Mina Tadrous, Dean Elterman, Wayne Khuu, Muhammad M Mamdani, David N Juurlink, Tara Gomes
INTRODUCTION: Medication is an important option for patients with overactive bladder (OAB), with four different drugs approved over the last 10 years including the first non-anticholinergic treatment, mirabegron. We set out to describe the number and rate of users of medication for the management of OAB over the last 15 years among residents of Ontario, Canada covered by the public drug programs. METHODS: We conducted a population-based, repeated cross-sectional study examining quarterly publically-funded prescription claims for OAB medications from January 2000 to June 2016 in Ontario, Canada...
December 22, 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/29274228/prior-authorization-and-canadian-public-utilization-of-direct-acting-oral-anticoagulants
#10
Lulu Gao, Mina Tadrous, Sandra Knowles, Muhammad Mamdani, J Michael Paterson, David Juurlink, Tara Gomes
PURPOSE: Provincial public drug formularies in Canada have different mechanisms for reimbursement of direct-acting oral anticoagulants (DOACs). We investigate how these differences influence DOAC utilization and expenditure across the country. METHODS: We conducted a population-based, cross-sectional study of all out-patient prescriptions for OACs dispensed to public beneficiaries between January 1, 2010, and June 30, 2015. We calculated quarterly rates of OAC use and expenditures stratified by OAC type and province...
November 2017: Healthcare Policy, Politiques de Santé
https://www.readbyqxmd.com/read/29261441/challenges-interpreting-chemoprevention-studies-using-observational-data
#11
Madhur Nayan, David N Juurlink, Antonio Finelli, Girish Kulkarni, Robert J Hamilton
No abstract text is available yet for this article.
February 20, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29226327/medication-use-and-kidney-cancer-survival-a-population-based-study
#12
Madhur Nayan, David N Juurlink, Peter C Austin, Erin M Macdonald, Antonio Finelli, Girish S Kulkarni, Robert J Hamilton
Several studies demonstrate that use of commonly prescribed medications is associated with improved survival in various malignancies. Methods of classifying medication use in many of these studies, however, do not account for intermittent or cumulative use. Moreover, there are limited data in kidney cancer. Therefore, we performed a population-based cohort study utilizing healthcare databases in Ontario, Canada. We identified patients aged ≥65 with an incident diagnosis of kidney cancer between 1997 and 2013 and examined use of nine putative anti-neoplastic medications using prescription claims...
May 1, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29216018/impact-of-a-graduated-approach-on-opioid-initiation-and-loss-of-earnings-following-workplace-injury-a-time-series-analysis
#13
Tara Gomes, June Duesburry, Marc-Erick Theriault, Donna Bain, Samantha Singh, Diana Martins, David N Juurlink
OBJECTIVE: The aim of this study was to explore the impact of the Ontario Workplace Safety and Insurance Board's (WSIB's) graduated approach to opioid management on opioid prescribing and disability claim duration. METHODS: We studied patterns of opioid use and disability claim duration among Ontarians who received benefits through the WSIB between 2002 and 2013. We used interventional time series analysis to assess the impact of the WSIB graduated formulary on these trends...
December 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29117991/availability-of-naloxone-in-canadian-pharmacies-a-population-based-survey
#14
Alex M Cressman, Graham Mazereeuw, Qi Guan, Wenting Jia, Tara Gomes, David N Juurlink
BACKGROUND: Naloxone is life-saving when administered after opioid overdose. In March 2016, the Canadian government made the antidote available without prescription, but anecdotal reports suggest members of the public have difficulty in procuring it. We examined the availability of naloxone in community pharmacies across Canada. METHODS: We identified community pharmacies in Canada ( n = 10 296) and randomly selected 506, stratified using proportionate allocation by population size...
November 8, 2017: CMAJ Open
https://www.readbyqxmd.com/read/29111110/impact-of-injectable-furosemide-hospital-shortage-on-congestive-heart-failure-outcomes-a-time-series-analysis
#15
MULTICENTER STUDY
Vivian S Tan, Danielle M Nash, Eric McArthur, Arsh K Jain, Amit X Garg, David N Juurlink, Matthew A Weir
BACKGROUND: Beginning in February 2012, there was a shortage of injectable furosemide in the province of Ontario, Canada. The objective of this study was to assess the effects of the furosemide shortage on heart failure outcomes in Ontario, Canada. METHODS: We determined which hospitals experienced a shortage of injectable furosemide using an online survey. We then used health administrative data to identify all patients who presented to those hospitals with congestive heart failure...
November 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28986124/real-world-health-care-utilization-and-effectiveness-of-omalizumab-for-the-treatment-of-severe-asthma
#16
Mina Tadrous, Wayne Khuu, Gerald Lebovic, Matthew B Stanbrook, Diana Martins, J Michael Paterson, Muhammad M Mamdani, David N Juurlink, Tara Gomes
BACKGROUND: Omalizumab is indicated for the treatment of moderate to severe asthma. There is limited observational evidence on the costs and effectiveness of omalizumab. OBJECTIVE: To examine the costs and effectiveness of omalizumab for treatment of severe asthma relative to nonusers. METHODS: We conducted a within-person repeated-measures matched cohort study in Ontario, Canada from April 1, 2012 to March 31, 2014. Continuous users of omalizumab were matched with up to 4 nonusers according to age, sex, recent specialist visits, oral corticosteroid use, asthma severity, and Charlson comorbidity score...
January 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28972983/gabapentin-opioids-and-the-risk-of-opioid-related-death-a-population-based-nested-case-control-study
#17
Tara Gomes, David N Juurlink, Tony Antoniou, Muhammad M Mamdani, J Michael Paterson, Wim van den Brink
BACKGROUND: Prescription opioid use is highly associated with risk of opioid-related death, with 1 of every 550 chronic opioid users dying within approximately 2.5 years of their first opioid prescription. Although gabapentin is widely perceived as safe, drug-induced respiratory depression has been described when gabapentin is used alone or in combination with other medications. Because gabapentin and opioids are both commonly prescribed for pain, the likelihood of co-prescription is high...
October 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28970259/rethinking-doing-well-on-chronic-opioid-therapy
#18
REVIEW
David N Juurlink
No abstract text is available yet for this article.
October 2, 2017: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/28919644/heterogeneous-catalytic-oxidation-of-simple-alcohols-by-transition-metals
#19
Leon Jacobse, Sebastiaan O Vink, Sven Wijngaarden, Ludo B F Juurlink
The "exploding" flask demonstration presents a well-known illustration of heterogeneous catalyzed methanol oxidation. We find that for the same vapor pressure, the demonstration also works for all primary and secondary alcohols up to butanol but not for a tertiary alcohol. Also, we show that the demonstration works for a large range of transition metal catalysts. Hence, this demonstration, which is often applied for the repetitive explosions when methanol is used, may also be used to argue the requirement of initial dehydrogenation of the alcohol to an aldehyde in the catalytic reaction mechanism to support the general insensitivity to reactant molecules in heterogeneous catalysis in contrast to biological catalysis and to provide proof for activity trends as often depicted by volcano plots...
September 12, 2017: Journal of Chemical Education
https://www.readbyqxmd.com/read/28919643/misconceptions-in-the-exploding-flask-demonstration-resolved-through-students-critical-thinking
#20
Rick Spierenburg, Leon Jacobse, Iris de Bruin, Daan J van den Bos, Dominique M Vis, Ludo B F Juurlink
As it connects to a large set of important fundamental ideas in chemistry and analytical techniques discussed in high school chemistry curricula, we review the exploding flask demonstration. In this demonstration, methanol vapor is catalytically oxidized by a Pt wire catalyst in an open container. The exothermicity of reactions occurring at the catalytic surface heats the metal to the extent that it glows. When restricting reactant and product gas flow, conditions may favor repetitive occurrence of a small explosion...
September 12, 2017: Journal of Chemical Education
keyword
keyword
79453
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"