keyword
MENU ▼
Read by QxMD icon Read
search

Rodger

keyword
https://www.readbyqxmd.com/read/29151277/mammalian-mitophagy-from-in-vitro-molecules-to-in-vivo-models
#1
REVIEW
Catherine E Rodger, Thomas G McWilliams, Ian G Ganley
The autophagic turnover of mitochondria, termed mitophagy, is thought to play an essential role in not only maintaining the health of the mitochondrial network, but also that of the cell and organism as a whole. We have come a long way in identifying the molecular components required for mitophagy through extensive in vitro work and cell line characterisation, yet the physiological significance and context of these pathways remains largely unexplored. This is highlighted by the recent development of new mouse models that have revealed a striking level of variation in mitophagy, even under normal conditions...
November 19, 2017: FEBS Journal
https://www.readbyqxmd.com/read/29148336/predictors-of-medication-adherence-in-the-elderly-the-role-of-mental-health
#2
Jo E Rodgers, Emily M Thudium, Hadi Beyhaghi, Carla A Sueta, Khalid A Alburikan, Anna M Kucharska-Newton, Patricia P Chang, Sally C Stearns
The aging population routinely has comorbid conditions requiring complicated medication regimens, yet nonadherence can preclude optimal outcomes. This study explored the association of adherence in the elderly with demographic, socioeconomic, and disease burden measures. Data were from the fifth visit (2011-2013) for 6,538 participants in the Atherosclerosis Risk in Communities Study, conducted in four communities. The Morisky-Green-Levine Scale measured self-reported adherence. Forty percent of respondents indicated some nonadherence, primarily due to poor memory...
March 1, 2017: Medical Care Research and Review: MCRR
https://www.readbyqxmd.com/read/29148256/toward-standardization-of-care-the-feeding-readiness-assessment-after-congenital-cardiac-surgery
#3
Daniel E Ehrmann, Matthew Mulvahill, Shaunda Harendt, Jessica Church, Amy Stimmler, Piyagarnt Vichayavilas, Sanja Batz, Jennifer Rodgers, Michael DiMaria, James Jaggers, Cindy Barrett, Jon Kaufman
BACKGROUND: Feeding practices after neonatal and congenital heart surgery are complicated and variable, which may be associated with prolonged hospitalization length of stay (LOS). Systematic assessment of feeding skills after cardiac surgery may earlier identify those likely to have protracted feeding difficulties, which may promote standardization of care. METHODS: Neonates and infants ≤3 months old admitted for their first cardiac surgery were retrospectively identified during a 1-year period at a single center...
November 17, 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/29143929/a-comparison-of-the-energetic-cost-of-running-in-marathon-racing-shoes
#4
Wouter Hoogkamer, Shalaya Kipp, Jesse H Frank, Emily M Farina, Geng Luo, Rodger Kram
BACKGROUND: Reducing the energetic cost of running seems the most feasible path to a sub-2-hour marathon. Footwear mass, cushioning, and bending stiffness each affect the energetic cost of running. Recently, prototype running shoes were developed that combine a new highly compliant and resilient midsole material with a stiff embedded plate. OBJECTIVE: The aim of this study was to determine if, and to what extent, these newly developed running shoes reduce the energetic cost of running compared with established marathon racing shoes...
November 16, 2017: Sports Medicine
https://www.readbyqxmd.com/read/29142588/characterization-of-hormonal-receptors-and-human-epidermal-growth-factor-receptor-2-in-tissues-of-women-with-breast-cancer-at-muhimbili-national-hospital-dar-es-salaam-tanzania
#5
Amos Rodger Mwakigonja, Nyanda Elias Lushina, Ally Mwanga
Background: Breast cancer is a leading cause of morbidity and deaths among women worldwide. In Tanzania there is no published data on human epidermal growth receptor-2 (HER2/neu) expression in breast carcinoma. Hormonal receptors and HER2/neu status reportedly influence post-mastectomy adjuvant therapy and predict treatment outcome and prognosis. Here we evaluate hormonal receptors and HER-2 status in biopsies of women with breast cancer at Muhimbili National Hospital (MNH). Methods: A cross-sectional study of female breast post-modified radical mastectomy (MRM)/incisional biopsies confirmed to be carcinoma at the Histopathology Unit (January-December 2013)...
2017: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/29141178/peri-conception-and-first-trimester-diet-modifies-reproductive-development-in-bulls
#6
K J Copping, M D Ruiz-Diaz, C S Rutland, N P Mongan, M J Callaghan, I C McMillen, R J Rodgers, V E A Perry
Nutritional perturbation during gestation alters male reproductive development in rodents and sheep. In cattle both the developmental trajectory of the feto-placental unit and its response to dietary perturbations is dissimilar to that of these species. This study examined the effects of dietary protein perturbation during the peri-conception and first trimester periods upon reproductive development in bulls. Nulliparous heifers (n=360) were individually fed a high- or low-protein diet (HPeri and LPeri) from 60 days before conception...
November 16, 2017: Reproduction, Fertility, and Development
https://www.readbyqxmd.com/read/29139549/elevated-potassium-outward-currents-in-hyperoxia-treated-atrial-cardiomyocytes
#7
Z Vysotskaya, B Chidipi, J L Rodgers, X Tang, E Samal, N Kolliputi, S Mohapatra, E S Bennett, S K Panguluri
Supplementation of 100% oxygen is a very common intervention in intensive care units (ICU) and critical care centers for patients with dysfunctional lung and lung disorders. Although there is advantage in delivering sufficient levels of oxygen, hyperoxia is reported to be directly associated with increasing in-hospital deaths. Our previous studies reported ventricular and electrical remodeling in hyperoxia treated mouse hearts, and in this article, for the first time, we are investigating the effects of hyperoxia on atrial electrophysiology using whole-cell patch-clamp electrophysiology experiments along with assessment of Kv1...
November 15, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29134765/developmental-retinal-ganglion-cell-death-and-retinotopicity-of-the-murine-retinocollicular-projection
#8
Jamie Beros, Jennifer Rodger, Alan R Harvey
During mammalian visual system development, retinal ganglion cells (RGCs) undergo extensive apoptotic death. In mouse retina, approximately 50% of RGCs present at birth (postnatal day 0; P0) die by P5, at a time when axons innervate central targets such as the superior colliculus (SC). We examined whether RGCs that make short-range axonal targeting errors within the contralateral SC are more likely to be eliminated during the peak period of RGC death (P1-P5), compared with RGCs initially making more accurate retinotopic connections...
November 14, 2017: Developmental Neurobiology
https://www.readbyqxmd.com/read/29134122/platelet-phosphorylated-tdp-43-an-exploratory-study-for-a-peripheral-surrogate-biomarker-development-for-alzheimer-s-disease
#9
Rodger Wilhite, Jessica M Sage, Abdurrahman Bouzid, Tyler Primavera, Abdulbaki Agbas
Aim: Alzheimer's disease (AD) and other forms of dementia create a noncurable disease population in world's societies. To develop a blood-based biomarker is important so that the remedial or disease-altering therapeutic intervention for AD patients would be available at the early stage. Materials & methods: TDP-43 levels were analyzed in postmortem brain tissue and platelets of AD and control subjects. Results: We observed an increased TDP-43 (<60%) in postmortem AD brain regions and similar trends were also observed in patient's platelets...
November 2017: Future Science OA
https://www.readbyqxmd.com/read/29131748/a-multicentre-clinical-evaluation-of-a-hydro-responsive-wound-dressing-the-glasgow-experience
#10
H Hodgson, D Davidson, A Duncan, J Guthrie, E Henderson, M MacDiarmid, K McGown, V Pollard, R Potter, A Rodgers, A Wilson, J Horner, M Doran, S Simm, R Taylor, A Rogers, M G Rippon, M Colgrave
OBJECTIVE: Our aim was to assess the effectiveness of hydro-responsive wound dressing (HRWD) in debridement and wound bed preparation of a variety of acute and chronic wounds that presented with devitalised tissue needing removal so that healing may proceed. METHOD: This was a non-comparative evaluation of acute and chronic wounds that required debridement as part of their normal treatment regimen. Clinicians recorded wound changes including a subjective assessment level of devitalised tissue and wound bed preparation, presence of pain, wound status (e...
November 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/29127713/prevalence-of-key-care-indicators-of-pressure-injuries-incontinence-malnutrition-and-falls-among-older-adults-living-in-nursing-homes-in-new-zealand
#11
Jenny Carryer, Jan Weststrate, Polly Yeung, Vivien Rodgers, Andy Towers, Mark Jones
Pressure injuries, incontinence, malnutrition, and falls are important indicators of the quality of care in healthcare settings, particularly among older people, but there is limited information on their prevalence in New Zealand (NZ). The aim of this study was to establish the prevalence of these four problems among older people in nursing home facilities. The cross-sectional study was an analysis of data collected on a single day for the 2016 National Care Indicators Programme-New Zealand (NCIP-NZ). The sample included 276 people ages 65 and older who were residents in 13 nursing home facilities in a geographically diverse area of central NZ...
November 11, 2017: Research in Nursing & Health
https://www.readbyqxmd.com/read/29126481/quantum-chemical-fragment-precursor-tests-accelerating-de-novo-annotation-of-tandem-mass-spectra
#12
Benjamin G Janesko, Li Li, Rodger Mensing
Tandem mass spectrometry is widely used to assign and distinguish chemical structures in proteomics, metabolomics, lipidomics, and many other areas. Spectral annotation remains a major bottleneck. Our "Quantum Chemical Fragment Precursor Tests" (QC-FPT) approach brings the accuracy and generality of modern quantum chemistry to combinatorial-search-based computer-aided spectral annotation. QC-FPT takes as input the dominant fragment peaks from a particular experiment, and one or more chemically reasonable hypotheses for the precursor ion's three-dimensional structure...
December 1, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/29125974/investigations-of-trace-and-toxic-elements-of-kidney-stones-from-two-different-sudanese-areas-by-%C3%A2%C2%B5-pixe-using-nuclear-microprobe-nmp
#13
REVIEW
M E M Eisa, C A Pineda-Vargas, Sami E E Salah, A L Rodgers
In this study 14 kidney stones (oxalate and phosphate stones) collected from two Sudanese hospitals Particle Induced X ray Emission (µ-PIXE). This technique was used to investigate the matrix as well as the trace element compositions of kidney stones on a microscopic scale using 1.5MeV proton energy. Significant differences in elements content across the groups were found by applying statistical methods. Trace elements such as P,Ca, Fe, Ni, Cu, Zn, Se, Sr, Br, and Pb showed a possible linear relationship of the mean profile for trace elements for each group of stones...
October 18, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/29123473/neurobehavioral-abnormalities-associated-with-executive-dysfunction-after-traumatic-brain-injury
#14
REVIEW
Rodger Ll Wood, Andrew Worthington
Objective: This article will address how anomalies of executive function after traumatic brain injury (TBI) can translate into altered social behavior that has an impact on a person's capacity to live safely and independently in the community. Method: Review of literature on executive and neurobehavioral function linked to cognitive ageing in neurologically healthy populations and late neurocognitive effects of serious TBI. Information was collated from internet searches involving MEDLINE, PubMed, PyscINFO and Google Scholar as well as the authors' own catalogs...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/29122266/tone-as-a-health-concept-an-analysis
#15
Donald McDowall, Elizabeth Emmanuel, Sandra Grace, Marilyn Chaseling
STUDY DESIGN: Concept analysis. INTRODUCTION: This paper is a report on the analysis of the concept of tone in chiropractic. PURPOSE: The purpose of this paper is to clarify the concept of tone as originally understood by Daniel David Palmer from 1895 to 1914 and to monitor its evolution over time. METHODS: Data was sourced from Palmer's original work, published between 1895 and 1914. A literature search from 1980 to 2016 was also performed on the online databases CINHAL, PubMed and Scopus with key terms including 'tone', 'chiropractic', 'Palmer', 'vitalism', 'health', 'homeostasis', 'holism' and 'wellness'...
November 2017: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/29121259/exercise-ameliorates-neurocognitive-impairments-in-a-translational-model-of-pediatric-radiotherapy
#16
Iman Sahnoune, Taeko Inoue, Shelli R Kesler, Shaefali P Rodgers, Omaima M Sabek, Steen E Pedersen, Janice A Zawaski, Katharine H Nelson, M Douglas Ris, J Leigh Leasure, M Waleed Gaber
Background: While CRT is an effective treatment, healthy areas surrounding irradiation sites are negatively affected. Frontal lobe functions involving attention, processing speed and inhibition control are impaired. These deficits appear months to years after CRT and impair quality-of-life. Exercise has been shown to rejuvenate the brain and aid in recovery post-injury through its effects on neurogenesis and cognition. Methods: We developed a juvenile rodent CRT model that reproduces neurocognitive deficits...
November 7, 2017: Neuro-oncology
https://www.readbyqxmd.com/read/29117234/compensatory-selection-for-roads-over-natural-linear-features-by-wolves-in-northern-ontario-implications-for-caribou-conservation
#17
Erica J Newton, Brent R Patterson, Morgan L Anderson, Arthur R Rodgers, Lucas M Vander Vennen, John M Fryxell
Woodland caribou (Rangifer tarandus caribou) in Ontario are a threatened species that have experienced a substantial retraction of their historic range. Part of their decline has been attributed to increasing densities of anthropogenic linear features such as trails, roads, railways, and hydro lines. These features have been shown to increase the search efficiency and kill rate of wolves. However, it is unclear whether selection for anthropogenic linear features is additive or compensatory to selection for natural (water) linear features which may also be used for travel...
2017: PloS One
https://www.readbyqxmd.com/read/29117041/repeated-ramp-tests-on-stable-lvad-patients-reveal-patient-specific-hemodynamic-fingerprint
#18
Teruhiko Imamura, Daniel Burkhoff, Daniel Rodgers, Sirtaz Adatya, Nitasha Sarswat, Gene Kim, Jayant Raikhelkar, Takeyoshi Ota, Tae Song, Colleen Juricek, Valluvan Jeevanandam, Gabriel Sayer, Nir Uriel
Hemodynamic speed ramp tests are used in left ventricular assist device (LVAD) patients to guide speed adjustment and medical therapies. However, the reproducibility of these tests is unknown. In this prospective study, clinically stable LVAD patients underwent echocardiography and right heart catheterization ramp tests followed by a repeat test within 2 years as per institutional protocol. Sixteen patients (61.8 ± 10.5 years old, 50% male, eight with HeartMate II and eight with HVAD) underwent repeated ramp testing...
November 7, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29112635/peritoneal-carcinomatosis-presenting-as-a-sister-mary-joseph-nodule
#19
John DeBardeleben, Micah Cohen, Shuchi K Rodgers
No abstract text is available yet for this article.
November 4, 2017: Ultrasound Quarterly
https://www.readbyqxmd.com/read/29105621/adalimumab-etanercept-and-ustekinumab-for-treating-plaque-psoriasis-in-children-and-young-people-systematic-review-and-economic-evaluation
#20
Ana Duarte, Teumzghi Mebrahtu, Pedro Saramago Goncalves, Melissa Harden, Ruth Murphy, Stephen Palmer, Nerys Woolacott, Mark Rodgers, Claire Rothery
BACKGROUND: Psoriasis is a chronic inflammatory disease that predominantly affects the skin. Adalimumab (HUMIRA(®), AbbVie, Maidenhead, UK), etanercept (Enbrel(®), Pfizer, New York, NY, USA) and ustekinumab (STELARA(®), Janssen Biotech, Inc., Titusville, NJ, USA) are the three biological treatments currently licensed for psoriasis in children. OBJECTIVE: To determine the clinical effectiveness and cost-effectiveness of adalimumab, etanercept and ustekinumab within their respective licensed indications for the treatment of plaque psoriasis in children and young people...
November 2017: Health Technology Assessment: HTA
keyword
keyword
79452
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"