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https://www.readbyqxmd.com/read/29774474/perspectives-of-children-family-caregivers-and-health-professionals-about-pediatric-oncology-symptoms-a-systematic-review
#1
REVIEW
Lei Cheng, Liying Wang, Mengxue He, Sheng Feng, Yehui Zhu, Cheryl Rodgers
OBJECTIVES: To evaluate the existing body of evidence to determine the current state of knowledge regarding the perspectives of the following groups: (1) children with cancer, (2) family caregivers, and (3) healthcare professionals, about symptoms, as well as factors that may influence the symptom reports. METHODS: A systematic search was performed for all types of studies that included the perspectives of at least two groups of participants' symptom reports. Children included anyone younger than 19 years of age who was diagnosed with any type of cancer...
May 17, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29772030/correction-gestational-dietary-protein-is-associated-with-sex-specific-decrease-in-blood-flow-fetal-heart-growth-and-post-natal-blood-pressure-of-progeny
#2
Juan H Hernandez-Medrano, Katrina J Copping, Andrew Hoare, Wendela Wapanaar, Rosalie Grivell, Tim Kuchel, Giuliana Miguel-Pacheco, I Caroline McMillen, Raymond J Rodgers, Viv E A Perry
[This corrects the article DOI: 10.1371/journal.pone.0125694.].
2018: PloS One
https://www.readbyqxmd.com/read/29771097/-mechanical-ventilation-with-explicit-recall-a-concept-analysis
#3
Mylène Suzie Michaud, Marilou Gagnon
Mechanical ventilation in the intensive care unit requires the use of medication to reduce pain, discomfort, anxiety, and agitation. An explicit recall refers to the phenomenon where the person remembers the perceptions that occurred under sedation during mechanical ventilation. Severe psychological consequences may occur as a result of an explicit recall. This phenomenon is not well-defined and there is no common language in the literature. A conceptual analysis was carried out using Rodgers' evolutionary method in order to clarify the concept of explicit recall...
March 2018: Recherche en Soins Infirmiers
https://www.readbyqxmd.com/read/29770793/pulmonary-embolism
#4
REVIEW
Menno V Huisman, Stefano Barco, Suzanne C Cannegieter, Gregoire Le Gal, Stavros V Konstantinides, Pieter H Reitsma, Marc Rodger, Anton Vonk Noordegraaf, Frederikus A Klok
Pulmonary embolism (PE) is caused by emboli, which have originated from venous thrombi, travelling to and occluding the arteries of the lung. PE is the most dangerous form of venous thromboembolism, and undiagnosed or untreated PE can be fatal. Acute PE is associated with right ventricular dysfunction, which can lead to arrhythmia, haemodynamic collapse and shock. Furthermore, individuals who survive PE can develop post-PE syndrome, which is characterized by chronic thrombotic remains in the pulmonary arteries, persistent right ventricular dysfunction, decreased quality of life and/or chronic functional limitations...
May 17, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29768407/the-health-e-babies-app-for-antenatal-education-feasibility-for-socially-disadvantaged-women
#5
Julia A Dalton, Dianne Rodger, Michael Wilmore, Sal Humphreys, Andrew Skuse, Claire T Roberts, Vicki L Clifton
BACKGROUND: The use of mobile technology such as phone applications (apps) has been proposed as an efficient means of providing health and clinical information in a variety of healthcare settings. We developed the Health-e Babies app as an Android smart phone application for pregnant women attending a tertiary hospital in a low socio-economic community, with the objective of providing health information about early pregnancy that would increase maternal confidence and reduce anxiety. Based on our earlier research, this form of health communication was viewed as a preferred source of information for women of reproductive age...
2018: PloS One
https://www.readbyqxmd.com/read/29767357/a-guide-for-designing-and-analyzing-rna-seq-data
#6
Aniruddha Chatterjee, Antonio Ahn, Euan J Rodger, Peter A Stockwell, Michael R Eccles
The identity of a cell or an organism is at least in part defined by its gene expression and therefore analyzing gene expression remains one of the most frequently performed experimental techniques in molecular biology. The development of the RNA-Sequencing (RNA-Seq) method allows an unprecedented opportunity to analyze expression of protein-coding, noncoding RNA and also de novo transcript assembly of a new species or organism. However, the planning and design of RNA-Seq experiments has important implications for addressing the desired biological question and maximizing the value of the data obtained...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29761467/using-wormbase-parasite-an-integrated-platform-for-exploring-helminth-genomic-data
#7
Bruce J Bolt, Faye H Rodgers, Myriam Shafie, Paul J Kersey, Matthew Berriman, Kevin L Howe
WormBase ParaSite ( parasite.wormbase.org ) is a comprehensive resource for the genomes of parasitic nematodes and flatworms (helminths). It currently includes genomic data for over 100 helminth species, adding value by way of consistent functional annotation, gene comparative analysis and gene expression analysis. We provide several ways of exploring the data including a choice of genome browsers, genome and gene summary pages, text and sequence searching, a query wizard, bulk downloads, and programmatic interfaces...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29757652/a-supramolecular-nucleoside-based-gel-molecular-dynamics-simulation-and-characterization-of-its-nanoarchitecture-and-self-assembly-mechanism
#8
Maria Angelerou, Pim W J M Frederix, Matthew Wallace, Bin Yang, Alison Rodger, Dave J Adams, Maria Marlow, Mischa Zelzer
Amongst the diversity of existing supramolecular hydrogels, nucleic acid-based hydrogels are of particular interest for potential drug delivery and tissue engineering applications because of their inherent biocompatibility. Hydrogel performance is directly related to nanostructure and the self-assembly mechanism of the material, an aspect that is not well understood for nucleic acid-based hydrogels in general and has not yet been explored for cytosine based hydrogels in particular. Herein, we use a broad range of experimental characterization techniques along with molecular dynamics simulations to demonstrate the complementarity and applicability of both approaches for nucleic acid-based gelators in general and propose the self-assembly mechanism for a novel supramolecular gelator, N4-octanoyl-2'-deoxycytidine...
May 14, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29752242/automated-fes-for-upper-limb-rehabilitation-following-stroke-and-spinal-cord-injury
#9
Edmund F Hodkin, Yuming Lei, Jonathan Humby, Isabel S Glover, Supriyo Choudhury, Hrishikesh Kumar, Monica A Perez, Helen Rodgers, Andrew Jackson
Neurorehabilitation aims to induce beneficial neural plasticity in order to restore function following injury to the nervous system. There is an increasing evidence that appropriately timed functional electrical stimulation (FES) can promote associative plasticity, but the dosage is critical for lasting functional benefits. Here, we present a novel approach to closed-loop control of muscle stimulation for the rehabilitation of reach-to-grasp movements following stroke and spinal cord injury (SCI). We developed a simple, low-cost device to deliver assistive stimulation contingent on users' self-initiated movements...
May 2018: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/29750335/universal-screening-of-both-endometrial-and-colon-cancers-increases-the-detection-of-lynch-syndrome
#10
Tomer Adar, Linda H Rodgers, Kristen M Shannon, Makoto Yoshida, Tianle Ma, Anthony Mattia, Gregory Y Lauwers, Anthony J Iafrate, Nicole M Hartford, Esther Oliva, Daniel C Chung
BACKGROUND: Lynch syndrome (LS) is the most common hereditary cause of colorectal cancer (CRC) and endometrial cancer (EC). Screening of all CRCs for LS is currently recommended, but screening of ECs is inconsistent. The objective of this study was to determine the added value of screening both CRC and EC tumors in the same population. METHODS: A prospective, immunohistochemistry (IHC)-based screening program for all patients with newly diagnosed CRCs and ECs was initiated in 2011 and 2013, respectively, at 2 centers (primary and tertiary)...
May 11, 2018: Cancer
https://www.readbyqxmd.com/read/29747158/delayed-return-to-estrus-following-treatment-with-the-gonadotrophin-releasing-hormone-agonist-lucrin-%C3%A2-depot-in-the-tammar-wallaby
#11
Ryan R Witt, Lyn A Hinds, John C Rodger
Gonadotrophin-releasing hormone agonists that induce a reversible contraceptive state in several marsupials have the potential to be used to synchronize estrus. We used a model macropod, the tammar wallaby (Notamacropus eugenii), to investigate whether Lucrin Depot (AbbVie), a GnRH agonist microsphere preparation, could (1) inhibit follicular development and estrus in a cycle reactivated by removal of pouch young (RPY) and (2) facilitate a synchronous return to estrus. Our results show that females reactivated with bromocriptine and RPY in early seasonal quiescence (July 2015) were inhibited by Lucrin Depot (0...
April 30, 2018: Theriogenology
https://www.readbyqxmd.com/read/29746576/graph-drawing-using-tabu-search-coupled-with-path-relinking
#12
Fadi K Dib, Peter Rodgers
Graph drawing, or the automatic layout of graphs, is a challenging problem. There are several search based methods for graph drawing which are based on optimizing an objective function which is formed from a weighted sum of multiple criteria. In this paper, we propose a new neighbourhood search method which uses a tabu search coupled with path relinking to optimize such objective functions for general graph layouts with undirected straight lines. To our knowledge, before our work, neither of these methods have been previously used in general multi-criteria graph drawing...
2018: PloS One
https://www.readbyqxmd.com/read/29734933/law-and-ethics-in-nursing-and-healthcare-an-introduction-2-nd-edition-law-and-ethics-in-nursing-and-healthcare-an-introduction-2-nd-edition-avery-graham-sage-publishing-london-2016-isbn-978-1-4129-6174-5-pb-392-pages-%C3%A2-24-29-kindle-%C3%A2-17-15
#13
https://www.readbyqxmd.com/read/29734506/predictors-of-quality-of-life-for-autistic-adults
#14
David Mason, Helen McConachie, Deborah Garland, Alex Petrou, Jacqui Rodgers, Jeremy R Parr
Research with adults on the autism spectrum is as yet limited in scope and quality. The present study describes quality of life (QoL) of a large sample of autistic adults in the UK and investigates characteristics that may be predictive of QoL. A total of 370 autistic adults from the Adult Autism Spectrum Cohort-UK (ASC-UK) completed the WHOQoL-BREF, and the Social Responsiveness Scale (SRS, autism symptom severity), along with the ASC-UK registration questionnaire giving information on mental health and their life situation...
May 7, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29734466/research-for-leveraging-food-policy-in-universal-eating-disorder-prevention
#15
Rachel F Rodgers, Kendrin Sonneville
Policy and legislation have emerged as important levers for universal prevention efforts in the context of eating disorders. However, to date, little attention has been paid to generating research that will inform opportunities to regulate the food environment, specifically the way that food is produced and marketed. The present paper aims to lay out a framework for research that will examine (1) the ways in which food industry may influence risk for eating disorders and (2) the impact of legislative efforts on eating disorder cognitions and behaviors...
May 7, 2018: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/29727304/the-frequency-characteristics-and-aetiology-of-stroke-mimic-presentations-a-narrative-review
#16
Graham McClelland, Helen Rodgers, Darren Flynn, Christopher I Price
A significant proportion of patients with acute stroke symptoms have an alternative 'mimic' diagnosis. A narrative review was carried out to explore the frequency, characteristics and aetiology of stroke mimics. Prehospital and thrombolysis-treated patients were described separately. Overall, 9972 studies were identified from the initial search and 79 studies were included with a median stroke mimic rate of 19% (range: 1-64%). The prehospital median was 27% (range: 4-43%) and the thrombolysis median 10% (range: 1-25%)...
May 1, 2018: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
https://www.readbyqxmd.com/read/29724339/detection-of-the-suspected-neurotoxin-%C3%AE-methylamino-l-alanine-bmaa-in-cyanobacterial-blooms-from-multiple-water-bodies-in-eastern-australia
#17
Brendan J Main, Lee C Bowling, Matthew P Padula, David P Bishop, Simon M Mitrovic, Gilles J Guillemin, Kenneth J Rodgers
The emerging toxin β-methylamino-l-alanine (BMAA) has been linked to the development of a number of neurodegenerative diseases in humans including amyotrophic lateral sclerosis (ALS), Alzheimer's disease, and Parkinson's disease. BMAA has been found to be produced by a range of cyanobacteria, diatoms, and dinoflagellates worldwide, and is present in freshwater, saltwater, and terrestrial ecosystems. Surface scum samples were collected from waterways in rural and urban New South Wales, Australia and algal species identified...
April 2018: Harmful Algae
https://www.readbyqxmd.com/read/29718372/defining-the-impact-of-melanopsin-missense-polymorphisms-using-in-vivo-functional-rescue
#18
Jessica Rodgers, Steven Hughes, Carina A Pothecary, Laurence A Brown, Doron G Hickey, Stuart N Peirson, Mark W Hankins
Melanopsin (OPN4) is an opsin photopigment expressed within intrinsically photosensitive retinal ganglion cells (ipRGCs) that mediate non-image forming (NIF) responses to light. Two single nucleotide polymorphisms (SNPs) in human melanopsin (hOPN4), Pro10Leu and Thr394Ile, have recently been associated with abnormal NIF responses to light, including Seasonal Affective Disorder. It has been suggested these behavioural changes are due to altered melanopsin signalling. However, there is currently no direct evidence to support this...
April 30, 2018: Human Molecular Genetics
https://www.readbyqxmd.com/read/29716266/mass-height-of-burst-and-source-receiver-distance-constraints-on-the-acoustic-coda-phase-delay-method
#19
Sarah Albert, Daniel Bowman, Arthur Rodgers, Douglas Seastrand
This research uses the acoustic coda phase delay method to estimate relative changes in air temperature between explosions with varying event masses and heights of burst. It also places a bound on source-receiver distance for the method. Previous studies used events with different shapes, height of bursts, and masses and recorded the acoustic codas at source-receiver distances less than 1 km. This research further explores the method using explosions that differ in mass (by up to an order of magnitude) and are placed at varying heights...
April 2018: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/29714829/the-duality-of-ocean-acidification-as-a-resource-and-a-stressor
#20
Sean D Connell, Zoë A Doubleday, Nicole R Foster, Sarah B Hamlyn, Christopher D G Harley, Brian Helmuth, Brendan P Kelaher, Ivan Nagelkerken, Kirsten L Rodgers, Gianluca Sarà, Bayden D Russell
Ecologically dominant species often define ecosystem states, but as human disturbances intensify, their subordinate counterparts increasingly displace them. We consider the duality of disturbance by examining how environmental drivers can simultaneously act as a stressor to dominant species and as a resource to subordinates. Using a model ecosystem, we demonstrate that CO2 -driven interactions between species can account for such reversals in dominance; i.e., the displacement of dominants (kelp forests) by subordinates (turf algae)...
May 2018: Ecology
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