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Microperimetry

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https://www.readbyqxmd.com/read/29346241/chronic-central-serous-chorioretinopathy-early-and-late-morphological-and-functional-changes-after-verteporfin-photodynamic-therapy
#1
Pierluigi Iacono, Massimiliano Tedeschi, Barbara Boccassini, Adele Chiaravalloti, Monica Varano, Mariacristina Parravano
PURPOSE: To describe early and late morphological and functional changes in subjects receiving photodynamic therapy (PDT) for chronic central serous chorioretinopathy. METHODS: Patients with chronic central serous chorioretinopathy were prospectively enrolled and received standard PDT. At the baseline examination, each subject underwent complete ophthalmological examination, including best-corrected visual acuity (BCVA) assessment, fluorescein angiography and indocyanine green angiography, spectral domain optical coherence tomography, and microperimetry...
January 16, 2018: Retina
https://www.readbyqxmd.com/read/29340643/association-of-low-luminance-questionnaire-with-objective-functional-measures-in-early-and-intermediate-age-related-macular-degeneration
#2
Atalie C Thompson, Ulrich F O Luhmann, Sandra S Stinnett, Lejla Vajzovic, Anupama Horne, Cynthia A Toth, Scott W Cousins, Eleonora M Lad
Purpose: To determine whether Low Luminance Questionnaire (LLQ) scores are associated with objective measures of visual function in early and intermediate age-related macular degeneration (AMD). Methods: Cross-sectional study of subjects with early AMD Age-Related Eye Disease Study (AREDS) stage 2, N = 33), intermediate AMD (AREDS stage 3, N = 47), and age-matched healthy controls (N = 21). Subjects were interviewed with the LLQ. Psychophysical tests performed included best-corrected visual acuity (BCVA), mesopic microperimetry, dark adaptometry (DA), low luminance visual acuity (LLVA), and cone contrast test (CCT)...
January 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29338130/correlation-between-morphological-characteristics-in-spectral-domain-optical-coherence-tomography-different-functional-tests-and-a-patient-s-subjective-handicap-in-acute-central-serous-chorioretinopathy
#3
Bianca S Gerendas, Julia-Sophie Kroisamer, Wolf Buehl, Sandra M Rezar-Dreindl, Katharina M Eibenberger, Eleonore Pablik, Ursula Schmidt-Erfurth, Stefan Sacu
PURPOSE: The purpose of this study was to identify quantitatively measurable morphologic optical coherence tomography (OCT) characteristics in patients with an acute episode of central serous chorioretinopathy (CSC) and evaluate their correlation to functional and psychological variables for their use in daily clinical practice. METHODS: Retinal thickness (RT), the height, area and volume of subretinal fluid (SRF)/pigment epithelium detachments were evaluated using the standardized procedures of the Vienna Reading Center...
January 16, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29299741/functional-and-structural-outcomes-of-ilm-peeling-in-uncomplicated-macula-off-rrd-using-microperimetry-en-face-oct
#4
Mohamed Gaber Ahmed Mohamed Eissa, Mohamad Amr Salah Eddin Abdelhakim, Tamer Ahmed Macky, Mohamed Mahmoud Khafagy, Hassan Aly Mortada
PURPOSE: To investigate functional and structural outcomes of internal limiting membrane (ILM) peeling during primary vitrectomy for uncomplicated macula-off rhegmatogenous retinal detachment (RRD). METHODS: In this prospective interventional randomized comparative study, 43 eyes (43 patients) were randomly divided into group A (20), and group B (23), with and without ILM peeling respectively. Patients were evaluated clinically, and by spectral-domain optical coherence tomography (SD-OCT) and microperimetry (MP) following silicone oil removal...
January 3, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29260077/femtosecond-laser-assisted-cataract-surgery-and-implantable-miniature-telescope
#5
Randal Pham, Burton Worrell, Phuc Nguyen, Keshav Narain
Purpose: This paper is a case report of the use of femtosecond laser for cataract surgery to implant an implantable miniature telescope for a patient with large central areas of geographic atrophy. Observations: On postoperative day 1 the patient's uncorrected visual acuity at near was 20/50. The cornea was clear and the patient reported no problem with navigation without occupational therapy training. Conclusions and importance: To our knowledge and confirmed by the manufacturer of the implantable miniature telescope this is the first case ever reported of a patient who has undergone femtosecond laser cataract surgery with corneal astigmatism correction and implantation of the implantable miniature telescope...
September 2017: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29249069/circumpapillary-microperimetry-to-detect-glaucoma-a-pilot-study-for-sector-based-comparison-to-circumpapillary-retinal-nerve-fiber-layer-measurement
#6
Yoshiyuki Kita, Gábor Hollό, Tsunehiro Saito, Akiko Murai, Ritsuko Kita, Akito Hirakata
PURPOSE: To evaluate and compare the diagnostic performance of circumpapillary microperimetry (MP) sensitivity and circumpapillary retinal nerve fiber layer thickness (cpRNFLT) measured with optical coherence tomography (OCT) for detection of early to moderate open-angle glaucoma. METHODS: Eleven eyes (11 patients) with early or moderate open-angle glaucoma and seven normal eyes (7 subjects) underwent MP (MP-3 microperimeter, NIDEK, Japan) and cpRNFLT measurement (RS-3000 Advance OCT, NIDEK, Japan) using an identical circumpapillary circle and similar measurement sectors...
December 16, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/29248331/evaluating-the-usefulness-of-mp-3-microperimetry-in-glaucoma-patients
#7
Masato Matsuura, Hiroshi Murata, Yuri Fujino, Kazunori Hirasawa, Mieko Yanagisawa, Ryo Asaoka
PURPOSE: The purpose of the current study was to evaluate the test-retest reproducibility and structure-function relationship of the MP-3 microperimeter, compared against the Humphrey Visual Analyzer (HFA). METHOD: ▪ DESIGN: Reliability and validity study SETTING: institutional, or clinical practice STUDY POPULATION: Thirty eyes of 30 primary open angle glaucoma patients (POAG) were enrolled. OBSERVATION PROCEDURES: VFs were measured twice with the MP-3 and HFA instruments, using the 10-2 test grid pattern in both perimeters...
December 14, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29244539/genotype-phenotype-variability-of-retinal-manifestation-in-primary-hyperoxaluria-type-1
#8
S Dulz, E Bigdon, Y Atiskova, F Schuettauf, R Cerkauskiene, J Oh, F Brinkert
BACKGROUND: Primary hyperoxaluria type 1 (PH1) is a rare congenital metabolic disorder of the glyoxylate pathway, which manifests with nephrocalcinosis, urolithiasis, and end-stage renal failure (ESRD) as well as deposition of oxalate crystals within ocular tissues. This report demonstrates classical ocular features of PH1 of the posterior pole and furthermore highlights the ocular genotype-phenotype variability among siblings with identical compound heterozygous alanine-glyoxylate aminotransferase (AGXT) mutations...
December 15, 2017: Ophthalmic Genetics
https://www.readbyqxmd.com/read/29242756/intersession-test-retest-variability-of-microperimetry-in-type-2-macular-telangiectasia
#9
Evan N Wong, Jehan D A De Soyza, David A Mackey, Ian J Constable, Fred K Chen
Purpose: Microperimetry is used as an endpoint in type 2 macular telangiectasia (mactel) trials. The change required for defining disease progression depends on measurement error. We determined the threshold of test-retest variability (TRV) of microperimetry in mactel. Methods: A prospective study was done of 24 patients with stable mactel enrolled in a tertiary eye clinic. Each patient underwent three sessions of microperimetry separated by a median of 28 days...
December 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/29222532/acute-solar-retinopathy-imaged-with-adaptive-optics-optical-coherence-tomography-angiography-and-en-face-optical-coherence-tomography
#10
Chris Y Wu, Michael E Jansen, Jorge Andrade, Toco Y P Chui, Anna T Do, Richard B Rosen, Avnish Deobhakta
Importance: Solar retinopathy is a rare form of retinal injury that occurs after direct sungazing. Objective: To enhance understanding of the structural changes that occur in solar retinopathy by obtaining high-resolution in vivo en face images. Design, Setting, and Participant: Case report of a young adult woman who presented to the New York Eye and Ear Infirmary with symptoms of acute solar retinopathy after viewing the solar eclipse on August 21, 2017...
December 7, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29206755/the-oasis-mp-1-substudy-characterization-of-the-effect-of-ocriplasmin-on-microperimetry-parameters
#11
SriniVas R Sadda, Pravin U Dugel, Victor H Gonzalez, Esmeralda Meunier, Petra Kozma
PURPOSE: To evaluate the effects of ocriplasmin and symptomatic vitreomacular adhesion resolution on visual fixation and macular sensitivity using microperimetry. METHODS: MP-1 parameters were analyzed from 3 OASIS sites after the use of standardized instruments and testing procedures over 24 months. RESULTS: A total of 27 patients (19 ocriplasmin, 8 sham) were evaluated. Mean distance of the preferred fixation locus to the anatomical center was farther in the sham group at baseline and farther in the sham versus ocriplasmin group throughout the study...
December 4, 2017: Retina
https://www.readbyqxmd.com/read/29190240/comparing-microperimetric-and-structural-findings-in-patients-with-branch-retinal-vein-occlusion-and-diabetic-macular-edema
#12
Amun Sachdev, Magdalena Edington, Rupal Morjaria, Victor Chong
PURPOSE: To compare retinal sensitivity and central retinal thickness in patients with focal diabetic macular edema (DME) and edema secondary to branch retinal vein occlusion (BRVO). METHODS: In this consecutive, cross-sectional, observational study, patients with either DME or BRVO underwent measurements for best-corrected visual acuity, microperimetry, and spectral domain optical coherence tomography. Retinal thickness and sensitivity were measured using Optos Spectral optical coherence tomography/scanning laser ophthalmoscopy (Optos plc, Dunfermline, Scotland, United Kingdom)...
November 22, 2017: Retina
https://www.readbyqxmd.com/read/29190229/correlation-between-outer-retinal-thickening-and-retinal-function-impairment-in-patients-with-idiopathic-epiretinal-membranes
#13
Andrea Cacciamani, Pamela Cosimi, Marta Di Nicola, Giuseppe Di Martino, Guido Ripandelli, Fabio Scarinci
PURPOSE: To examine the relationship between retinal layer thickness, retinal sensitivity, and visual function in patients with idiopathic epiretinal membrane using spectral domain optical coherence tomography automated segmentation algorithm. METHODS: Twenty-four eyes with epiretinal membrane and 12 control eyes were enrolled. Ophthalmic evaluations included best-corrected visual acuity, mean retinal sensitivity (MRS) of radial 10° and 4° areas tested with microperimetry, and measurements of 4 retinal layer thicknesses by means spectral domain optical coherence tomography...
November 28, 2017: Retina
https://www.readbyqxmd.com/read/29188526/measuring-central-retinal-sensitivity-using-microperimetry
#14
Mays Talib, Jasleen K Jolly, Camiel J F Boon
Microperimetry is an increasingly often used method of assessing the sensitivity of the central macula, analyzing fixation capabilities and loci, and accurately combining structural and functional information, even in the absence of stable fixation. Ongoing gene therapy trials have targeted the central retina, and utilized microperimetry as a main outcome measure for changes in retinal function. In retinal treatment planning, microperimetry has been used to assess the potential therapeutic window of opportunity...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29180846/different-fixation-targets-affect-retinal-sensitivity-obtained-by-microperimetry-in-normal-individuals
#15
Tomohiro Nizawa, Takayuki Baba, Masayasu Kitahashi, Toshiyuki Oshitari, Shuichi Yamamoto
Purpose: To determine the differences in the retinal sensitivities obtained by microperimetry with a single cross or a circular fixation target in normal individuals. Methods: Thirty-two eyes of 16 healthy volunteers (mean age 28.9±1.4 years, range 24-44 years) were studied. The retinal sensitivity of the central 0 degrees and of the mean central 2 degrees consisting of 8 points were determined independently using the two different fixation targets with Microperimeter 3...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29176603/the-association-between-visual-function-and-retinal-structure-in-chronic-central-serous-chorioretinopathy
#16
Aya Sugiura, Ryosuke Fujino, Nobuko Takemiya, Kimiko Shimizu, Masato Matsuura, Hiroshi Murata, Tatsuya Inoue, Ryo Obata, Ryo Asaoka
The purpose of the current study was to investigate the association between visual function and retinal structure in central serous chorioretinopathy (CSC). In 22 eyes of 22 chronic CSC patients with serous retinal detachment at the macula, retinal sensitivity was measured using MP3 microperimetry (NIDEK, Japan) and mean sensitivity within two degrees (MS2), four degrees (MS4) and six degrees (MS6), as well as foveal sensitivity (MS0), were calculated. Retinal structure was measured using optical coherence tomography (OCT, Spectralis, Heidelberg)...
November 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29150681/the-structure-function-relationship-measured-with-optical-coherence-tomography-and-a-microperimeter-with-auto-tracking-the-mp-3-in-patients-with-retinitis-pigmentosa
#17
Yuichi Asahina, Marie Kitano, Yohei Hashimoto, Mieko Yanagisawa, Hiroshi Murata, Tatsuya Inoue, Ryo Obata, Ryo Asaoka
The purpose of the current study was to investigate the structure-function relationship in patients with retinitis pigmentosa (RP) using optical coherence tomography and the MP-3 microperimeter. Visual field (VF) measurements were carried out using MP-3 microperimetry and the Humphrey Field Analyzer (HFA, Carl-Zeiss, CA), 22 eyes of 11 patients with a clinical diagnosis of RP, both with the 10-2 test grid pattern. Optical coherence tomography (OCT, Spectralis, Heidelberg, Germany) was also performed and the ellipsoid zone (EZ) was identified in the OCT image...
November 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29124422/perifoveal-interdigitation-zone-loss-in-hydroxychloroquine-toxicity-leads-to-subclinical-bull-s-eye-lesion-appearance-on-near-infrared-reflectance-imaging
#18
Avenell L Chew, Danuta M Sampson, Enid Chelva, Jane C Khan, Fred K Chen
PURPOSE: To characterize the ultrastructural and functional correlates of hydroxychloroquine (HCQ)-induced subclinical bull's eye lesion seen on near-infrared reflectance (NIR) imaging. METHODS: An asymptomatic 54-year-old male taking HCQ presented with paracentral ring-like scotoma, abnormal multifocal electroretinography (mfERG) and preserved ellipsoid zone on optical coherence tomography (OCT). Dense raster OCT was performed to create en face reflectivity maps of the interdigitation zone...
November 9, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29110945/the-progression-of-geographic-atrophy-secondary-to-age-related-macular-degeneration
#19
REVIEW
Monika Fleckenstein, Paul Mitchell, K Bailey Freund, SriniVas Sadda, Frank G Holz, Christopher Brittain, Erin C Henry, Daniela Ferrara
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) that leads to progressive and irreversible loss of visual function. Geographic atrophy is defined by the presence of sharply demarcated atrophic lesions of the outer retina, resulting from loss of photoreceptors, retinal pigment epithelium (RPE), and underlying choriocapillaris. These lesions typically appear first in the perifoveal macula, initially sparing the foveal center, and over time often expand and coalesce to include the fovea...
October 27, 2017: Ophthalmology
https://www.readbyqxmd.com/read/29084330/characterizing-the-natural-history-of-visual-function-in-choroideremia-using-microperimetry-and-multimodal-retinal-imaging
#20
RANDOMIZED CONTROLLED TRIAL
Jasleen K Jolly, Kanmin Xue, Thomas L Edwards, Markus Groppe, Robert E MacLaren
Purpose: Centripetal retinal degeneration in choroideremia (CHM) leads to early visual field restriction and late central vision loss. The latter marks an acute decline in quality of life but visual prognostication remains challenging. We investigated visual function in CHM by correlating best-corrected visual acuity (BCVA), microperimetry and multimodal imaging. Methods: Fifty-six consecutive CHM patients attending Oxford Eye Hospital were examined with BCVA, 10-2 microperimetry, optical coherence tomography, and fundus autofluorescence (AF)...
October 1, 2017: Investigative Ophthalmology & Visual Science
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