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https://www.readbyqxmd.com/read/28535032/applying-thienyl-side-chains-and-different-%C3%AF-bridge-to-aromatic-side-chain-substituted-indacenodithiophene-based-small-molecule-donors-for-high-performance-organic-solar-cells
#1
Jin-Liang Wang, Kai-Kai Liu, Sha Liu, Feng Liu, Hongbin Wu, Yong Cao, Thomas P Russell
A pair of linear tetrafluorinated small molecular donors, named as ThIDTTh4F and ThIDTSe4F, which are with tetrathienyl-substituted IDT as electron-rich central core, electron-deficient difluorobenzothiadiazole as acceptor units, and donor end-capping groups, but having differences in the π-bridge (thiophene and selenophene), were successfully synthesized and evaluated as donor materials in organic solar cells. Such π-bridge and core units in these small molecules play a decisive role in the formation of the nanoscale separation of the blend films, which were systematically investigated through absorption spectra, grazing incidence X-ray diffraction pattern, transmission electron microscopy images, resonant soft X-ray scattering profiles, and charge mobility measurement...
May 23, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28534679/laser-induced-photofragmentation-fluorescence-imaging-of-alkali-compounds-in-flames
#2
Tomas Leffler, Christian Brackmann, Marcus Aldén, Zhongshan Li
Laser-induced photofragmentation fluorescence has been investigated for the imaging of alkali compounds in premixed laminar methane-air flames. An ArF excimer laser, providing pulses of wavelength 193 nm, was used to photodissociate KCl, KOH, and NaCl molecules in the post-flame region and fluorescence from the excited atomic alkali fragment was detected. Fluorescence emission spectra showed distinct lines of the alkali atoms allowing for efficient background filtering. Temperature data from Rayleigh scattering measurements together with simulations of potassium chemistry presented in literature allowed for conclusions on the relative contributions of potassium species KOH and KCl to the detected signal...
June 2017: Applied Spectroscopy
https://www.readbyqxmd.com/read/28534407/cdse-nanoplatelet-films-with-controlled-orientation-of-their-transition-dipole-moment
#3
Yunan Gao, Mark C Weidman, William A Tisdale
Using liquid-liquid interfacial assembly, we control the deposition of CdSe nanoplatelets into face-down or edge-up configurations. Controlled assembly, combined with back focal plane imaging, enabled unambiguous determination of the transition dipole orientation. The transition dipole moment of the emissive band-edge exciton in CdSe nanoplatelets was found to be isotropically oriented within the plane of the nanoplatelet, with no measurable out-of-plane component and no preference for the long- or short-axis of the nanoplatelet...
May 23, 2017: Nano Letters
https://www.readbyqxmd.com/read/28534372/serum-expression-level-of-mir-504-can-differentiate-between-glioblastoma-multiforme-and-solitary-brain-metastasis-of-non-small-cell-lung-carcinoma
#4
Zheng Jin, Ri-Hua Jin, Chi Ma, Hai-Song Li, Hai-Yang Xu
PURPOSE: Gliomas are the most common primary intracranial tumors of the central nervous system (CNS), accounting for about one third of all brain tumors. Glioblastoma multiforme (GBM) is the aggressive grade IV glioma with survival as low as 2-5% in the second year post-diagnosis, hence necessitating efficient diagnostic markers. More than 50% of the non-small cell lung cancer (NSCLC) brain metastases are solitary lesions, often difficult to differentiate from gliomas by conventional imaging diagnostics...
March 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28531093/development-of-a-low-energy-x-ray-camera-for-the-imaging-of-secondary-electron-bremsstrahlung-x-ray-emitted-during-proton-irradiation-for-range-estimation
#5
Koki Ando, Mitsutaka Yamaguchi, Seiichi Yamamoto, Toshiyuki Toshito, Naoki Kawachi
Imaging of secondary electron bremsstrahlung x-ray emitted during proton irradiation is a possible method for measurement of the proton beam distribution in phantom. However, it is not clear that the method is used for range estimation of protons. For this purpose, we developed a low-energy x-ray camera and conducted imaging of the bremsstrahlung x-ray produced during irradiation of proton beams. We used a 20 mm  ×  20 mm  ×  1 mm finely grooved GAGG scintillator that was optically coupled to a one-inch square high quantum efficiency (HQE)-type position-sensitive photomultiplier tube to form an imaging detector...
May 22, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28529535/a-method-to-estimate-plant-density-and-plant-spacing-heterogeneity-application-to-wheat-crops
#6
Shouyang Liu, Fred Baret, Denis Allard, Xiuliang Jin, Bruno Andrieu, Philippe Burger, Matthieu Hemmerlé, Alexis Comar
BACKGROUND: Plant density and its non-uniformity drive the competition among plants as well as with weeds. They need thus to be estimated with small uncertainties accuracy. An optimal sampling method is proposed to estimate the plant density in wheat crops from plant counting and reach a given precision. RESULTS: Three experiments were conducted in 2014 resulting in 14 plots across varied sowing density, cultivars and environmental conditions. The coordinates of the plants along the row were measured over RGB high resolution images taken from the ground level...
2017: Plant Methods
https://www.readbyqxmd.com/read/28528461/novel-imaging-using-a-touchless-display-for-computer-assisted-hepato-biliary-surgery
#7
Yukio Oshiro, Kenoki Ohuchida, Toshiyuki Okada, Makoto Hashizume, Nobuhiro Ohkohchi
PURPOSE: We developed a touchless display system that allows the user to control the medical imaging software via hand gestures in the air. We conducted this study to verify the effectiveness of this novel touchless display system as a tool for assisting with surgical imaging. METHODS: The patient's computed tomography (CT) data are generally observed on a display during surgery. The "Dr. aeroTAP" touchless display system was developed to generate virtual mouse events based on the position of one hand...
May 20, 2017: Surgery Today
https://www.readbyqxmd.com/read/28520668/structural-connectivity-related-to-persistent-symptoms-after-mild-tbi-in-adolescents-and-response-to-aerobic-training-preliminary-investigation
#8
Weihong Yuan, Shari L Wade, Catherine Quatman-Yates, Jason A Hugentobler, Paul J Gubanich, Brad G Kurowski
OBJECTIVE: To quantify structural connectivity abnormalities in adolescents with mild traumatic brain injury (mTBI) and to investigate connectivity changes following aerobic training using graph theory and diffusion tensor imaging tractography. SETTING: Outpatient research setting. PARTICIPANTS: Twenty-two children (age: 15.83 ± 1.77 years, 10 females) with 4 to 16 weeks of persistent symptoms after mTBI and a matched healthy comparison group...
May 17, 2017: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/28513139/one-step-facile-synthesis-of-highly-magnetic-and-surface-functionalized-iron-oxide-nanorods-for-biomarker-targeted-applications
#9
Anamaria Ioana Orza, Hui Wu, Yaolin Xu, Qiong Lu, Hui Mao
We report a one-step method for facile and sustainable synthesis of magnetic iron oxide nanorods (or IONRs) with the mean lengths ranging from 25 to 50 nm and mean diameters ranging from 5 to 8 nm. The prepared IONRs are highly stable in aqueous media and can be surface functionalized for biomarker targeted applications. This synthetic strategy involves the reaction of iron(III) acetylacetonate with polyethyleneimine in the presence of oleylamine and phenylether, followed by thermal decomposition. Importantly, the length and diameter as well as the aspect ratio of prepared IONRs can be controlled by modulating the reaction parameters...
May 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28510483/improvement-in-ventilation-perfusion-mismatch-after-bronchoscopic-lung-volume-reduction-quantitative-image-analysis
#10
Sei Won Lee, Sang Min Lee, So Youn Shin, Tai Sun Park, Sang Young Oh, Namkug Kim, Yoonki Hong, Jae Seung Lee, Yeon-Mok Oh, Sang-Do Lee, Joon Beom Seo
Purpose To evaluate whether bronchoscopic lung volume reduction (BLVR) increases ventilation and therefore improves ventilation-perfusion (V/Q) mismatch. Materials and Methods All patients provided written informed consent to be included in this study, which was approved by the Institutional Review Board (2013-0368) of Asan Medical Center. The physiologic changes that occurred after BLVR were measured by using xenon-enhanced ventilation and iodine-enhanced perfusion dual-energy computed tomography (CT). Patients with severe emphysema plus hyperinflation who did not respond to usual treatments were eligible...
May 16, 2017: Radiology
https://www.readbyqxmd.com/read/28508191/investigations-of-severity-level-measurements-for-diabetic-macular-oedema-using-machine-learning-algorithms
#11
S Murugeswari, R Sukanesh
BACKGROUND: The macula is an important part of the human visual system and is responsible for clear and colour vision. Macular oedema happens when fluid and protein deposit on or below the macula of the eye and cause the macula to thicken and swell. Normally, it occurs due to diabetes called diabetic macular oedema. Diabetic macular oedema (DME) is one of the main causes of visual impairment in patients. AIM: The aims of the present study are to detect and localize abnormalities in blood vessels with respect to macula in order to prevent vision loss for the diabetic patients...
May 15, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/28507508/improving-focal-photostimulation-of-cortical-neurons-with-pre-derived-wavefront-correction
#12
Julian M C Choy, Sharmila S Sané, Woei M Lee, Christian Stricker, Hans A Bachor, Vincent R Daria
Recent progress in neuroscience to image and investigate brain function has been made possible by impressive developments in optogenetic and opto-molecular tools. Such research requires advances in optical techniques for the delivery of light through brain tissue with high spatial resolution. The tissue causes distortions to the wavefront of the incoming light which broadens the focus and consequently reduces the intensity and degrades the resolution. Such effects are detrimental in techniques requiring focal stimulation...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28506803/peg-coated-and-doxorubicin-loaded-multimodal-gadolinium-oxide-nanoparticles-for-simultaneous-drug-delivery-and-imaging-applications
#13
Shailja Kumar, Virendra Kumar Meena, Puja Panwar Hazari, Rakesh Kumar Sharma
We report water-in-oil microemulsion mediated synthesis of polyethylene glycol (PEG(1)) coated Gd2O3 nanoparticles (NPs(2)) loaded with fluorescent anti-cancer drug doxorubicin (dox(3)) for synchronous drug delivery, optical and magnetic resonance (MR(4)) imaging applications. These PEG covered Gd2O3 NPs loaded with dox (Gd-PEG-dox NPs) were found to possess spherical morphology with 13nm size as measured from TEM and the hydrodynamic diameter comes out to be 37nm as determined from DLS. Fluorescence spectra and fluorescence microscopy images confirmed optical activity of the NPs...
May 12, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28505496/inactivation-of-gram-bacteria-salmonella-enterica-by-chlorophyllin-based-photosensitization-mechanism-of-action-and-new-strategies-to-enhance-the-inactivation-efficiency
#14
Irina Buchovec, Viktorija Lukseviciūtė, Rita Kokstaite, Danute Labeikyte, Laura Kaziukonyte, Zivile Luksiene
This study is focused on the enhancement of susceptibility of Gram (-) bacteria S. enterica to chlorophyllin-based (Chl) photosensitization combining it with other antimicrobial tools. In order to find best combinations, the mechanism by which Chl-based photosensitization inactivates bacteria must be identified. Data confirmed that photosensitization (Chl 1.5×10(-5)M, for 1-120min, 405nm, 0-46.1J/cm(2)) reduced S. enterica population, just by 2.05 log (CFU/ml). Fluorimetric measurements indicated that just minor part of Chl was bound to Salmonella in suspension...
May 9, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28505422/oxygen-sensing-with-perfluorocarbon-loaded-ultraporous-mesostructured-silica-nanoparticles
#15
Amani L Lee, Clifford T Gee, Bradley P Weegman, Samuel A Einstein, Adam R Juelfs, Hattie L Ring, Katie R Hurley, Sam M Egger, Garrett Swindlehurst, Michael G Garwood, William C K Pomerantz, Christy L Haynes
Oxygen homeostasis is important in the regulation of biological function. Disease progression can be monitored by measur-ing oxygen levels, thus producing information for the design of therapeutic treatments. Non-invasive measurements of tissue oxygenation require the development of tools with minimal adverse effects and facile detection of features of interest. Fluo-rine magnetic resonance imaging (19F-MRI) exploits the intrinsic properties of perfluorocarbon (PFC) liquids for anatomical imaging, cell tracking, and oxygen sensing...
May 15, 2017: ACS Nano
https://www.readbyqxmd.com/read/28504813/improved-xenograft-efficiency-of-esophageal-adenocarcinoma-cell-lines-through-in-vivo-selection
#16
Elodie Melsens, Elly De Vlieghere, Benedicte Descamps, Christian Vanhove, Olivier De Wever, Wim Ceelen, Piet Pattyn
The present study aimed to investigate the orthotopic growth potential of two generally available esophageal adenocarcinoma cell lines, OE33 and OACM5 1.C, and a third in vivo selected subpopulation, OACM5 1.C SC1. One group of mice was subcutaneously injected in the hind legs. Tumor growth was measured with calipers. Another group was injected orthotopically in the distal esophageal wall through median laparotomy. Tumor development was evaluated macroscopically and confirmed microscopically. A subset of mice was evaluated with magnetic resonance imaging (MRI) to follow tumor progression...
May 15, 2017: Oncology Reports
https://www.readbyqxmd.com/read/28502451/benefits-and-shortcomings-in-the-employment-of-non-destructive-benthic-imagery-for-monitoring-of-hard-bottom-habitats
#17
Kolja Beisiegel, Alexander Darr, Mayya Gogina, Michael L Zettler
Hard-bottom habitats with complex topography and fragile epibenthic communities are still not adequately integrated in benthic monitoring programs as demanded by their potential ecosystem importance. While status indicators are defined by major EU directives, methods commonly used to provide measures are deficient in quantification of biota on hard surfaces. We address suitability of recent advancements in seafloor imaging to support monitoring activities. Comparative evaluation of the performance of high-resolution imagery and physical sampling (grab, dredge, SCUBA-diving) to detect taxonomic and functional components of epibenthos revealed that (1) with minimal habitat disturbance on large spatial scales imagery provides valuable cost-efficient assessment of complementary metrics of rocky reef habitats features and community structure, (2) despite poor taxonomic resolution image-derived data for habitat-forming taxa might be sufficient to infer richness of small sessile and mobile fauna, (3) physical collection is irreplaceable for robust record of species-richness to establish baselines and monitor changes on species level...
May 10, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28501744/strategy-for-improved-nh2-detection-in-combustion-environments-using-an-alexandrite-laser
#18
Christian Brackmann, Bo Zhou, Per Samuelsson, Vladimir A Alekseev, Alexander A Konnov, Zhongshan Li, Marcus Aldén
A new scheme for NH2 detection by means of laser-induced fluorescence (LIF) with excitation around wavelength 385nm, accessible using the second harmonic of a solid-state Alexandrite laser, is presented. Detection of NH2 was confirmed by identification of corresponding lines in fluorescence excitation spectra measured in premixed NH3-air flames and on NH2 radicals generated through NH3 photolysis in a nonreactive flow at ambient conditions. Moreover, spectral simulations allow for tentative NH2 line identification...
May 4, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28499946/lipid-drug-conjugate-nanoparticle-as-a-potential-nanocarrier-for-the-oral-delivery-of-pemetrexed-diacid-formulation-design-characterization-ex-vivo-and-in-vivo-assessment
#19
Kriti Soni, Ali Mujtaba, Kanchan Kohli
The present work was to develop lipid drug conjugated (LDC) nanoparticles for the potential oral delivery of pemetrexed diacid (PTX) and evaluation of its in vitro, ex vivo and in vivo potentials. The LDC was prepared by salt formation of PTX with stearic acid and followed by cold homogenization technique to produce the LDC nanoparticles. FTIR analysis of LDC proved the presence of amide bond in LDC powder indicating the conjugation between drug and lipid. LDC nanoparticles was found to have particle size 121...
May 10, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28495002/a-hybrid-energy-model-for-region-based-curve-evolution-application-to-cta-coronary-segmentation
#20
Muhammad Moazzam Jawaid, Ronak Rajani, Panos Liatsis, Constantino Carlos Reyes-Aldasoro, Greg Slabaugh
BACKGROUND AND OBJECTIVE: State-of-the-art medical imaging techniques have enabled non-invasive imaging of the internal organs. However, high volumes of imaging data make manual interpretation and delineation of abnormalities cumbersome for clinicians. These challenges have driven intensive research into efficient medical image segmentation. In this work, we propose a hybrid region-based energy formulation for effective segmentation in computed tomography angiography (CTA) imagery. METHODS: The proposed hybrid energy couples an intensity-based local term with an efficient discontinuity-based global model of the image for optimal segmentation...
June 2017: Computer Methods and Programs in Biomedicine
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