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https://www.readbyqxmd.com/read/28077020/relationship-between-18-f-flutemetamol-uptake-and-rbans-performance-in-non-demented-community-dwelling-older-adults
#1
Dustin B Hammers, Taylor J Atkinson, Bonnie C A Dalley, Kayla R Suhrie, Britney E Beardmore, Lance D Burrell, Kevin P Horn, Kelli M Rasmussen, Norman L Foster, Kevin Duff, John M Hoffman
OBJECTIVE: The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) has been used extensively for clinical care and in research for patients with mild cognitive impairment and Alzheimer's disease (AD); however, relatively few studies have evaluated the relationship between RBANS performance and AD imaging biomarkers. The purpose of the current study was to evaluate the association between a relatively new amyloid positron emission tomography imaging biomarker and performance on the RBANS...
January 12, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/28076974/topological-organization-of-whole-brain-white-matter-in-hiv-infection
#2
Laurie M Baker, Sarah Cooley, Ryan P Cabeen, David H Laidlaw, John A Joska, Jacqueline Hoare, Dan J Stein, Jodi Heaps-Woodruff, Lauren E Salminen, Robert H Paul
Infection with human immunodeficiency virus (HIV) is associated with neuroimaging alterations. However, little is known about the topological organization of whole-brain networks and the corresponding association with cognition. As such, we examined structural whole-brain white matter connectivity patterns and cognitive performance in 29 HIV+ young adults (mean age = 25.9) with limited or no HIV treatment history. HIV+ participants and demographically similar HIV- controls (n = 16) residing in South Africa underwent magnetic resonance imaging (MRI) and neuropsychological testing...
January 11, 2017: Brain Connectivity
https://www.readbyqxmd.com/read/28076353/a-topological-criterion-for-filtering-information-in-complex-brain-networks
#3
Fabrizio De Vico Fallani, Vito Latora, Mario Chavez
In many biological systems, the network of interactions between the elements can only be inferred from experimental measurements. In neuroscience, non-invasive imaging tools are extensively used to derive either structural or functional brain networks in-vivo. As a result of the inference process, we obtain a matrix of values corresponding to a fully connected and weighted network. To turn this into a useful sparse network, thresholding is typically adopted to cancel a percentage of the weakest connections...
January 11, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28076003/reducing-functional-mr-imaging-acquisition-times-by-optimizing-workflow
#4
Wilson B Chwang, Michael Iv, Jason Smith, Aleksandrs Kalnins, Jake Mickelsen, Roland Bammer, Dominik Fleischmann, David B Larson, Max Wintermark, Michael Zeineh
Functional magnetic resonance (MR) imaging is a complex, specialized examination that is able to noninvasively measure information critical to patient care such as hemispheric language lateralization ( 1 ). Diagnostic functional MR imaging requires extensive patient interaction as well as the coordinated efforts of the entire health care team. We observed in our practice at an academic center that the times to perform functional MR imaging examinations were excessively lengthy, making scheduling of the examination difficult...
January 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28074498/imaging-and-t2-relaxometry-of-short-t2-connective-tissues-in-the-knee-using-ultrashort-echo-time-double-echo-steady-state-utedess
#5
Akshay S Chaudhari, Bragi Sveinsson, Catherine J Moran, Emily J McWalter, Ethan M Johnson, Tao Zhang, Garry E Gold, Brian A Hargreaves
PURPOSE: To develop a radial, double-echo steady-state (DESS) sequence with ultra-short echo-time (UTE) capabilities for T2 measurement of short-T2 tissues along with simultaneous rapid, signal-to-noise ratio (SNR)-efficient, and high-isotropic-resolution morphological knee imaging. METHODS: THe 3D radial UTE readouts were incorporated into DESS, termed UTEDESS. Multiple-echo-time UTEDESS was used for performing T2 relaxometry for short-T2 tendons, ligaments, and menisci; and for Dixon water-fat imaging...
January 11, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28074302/enable-exportable-notation-and-bookmark-list-engine-an-interface-to-manage-tumor-measurement-data-from-pacs-to-cancer-databases
#6
Nikhil Goyal, Andrea B Apolo, Eliana D Berman, Mohammad Hadi Bagheri, Jason E Levine, John W Glod, Rosandra N Kaplan, Laura B Machado, Les R Folio
Oncologists evaluate therapeutic response in cancer trials based on tumor quantification following selected "target" lesions over time. At our cancer center, a majority of oncologists use Response Evaluation Criteria in Solid Tumors (RECIST) v1.1 quantifying tumor progression based on lesion measurements on imaging. Currently, our oncologists handwrite tumor measurements, followed by multiple manual data transfers; however, our Picture Archiving Communication System (PACS) (Carestream Health, Rochester, NY) has the ability to export tumor measurements, making it possible to manage tumor metadata digitally...
January 10, 2017: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/28072581/-131-i-activity-quantification-of-gamma-camera-planar-images
#7
Raquel Barquero, Hugo P Garcia, Monica G Incio, Pablo Minguez, Alexander Cardenas, Daniel Martínez, Michael Lassmann
A procedure to estimate the activity in target tissues in patients during the therapeutic administration of (131)I radiopharmaceutical treatment for thyroid conditions (hyperthyroidism and differentiated thyroid cancer) using a gamma camera (GC) with a high energy (HE) collimator, is proposed. Planar images are acquired for lesions of different sizes r, and at different distances d, in two HE GC systems. Defining a region of interest (ROI) on the image of size r, total counts n g are measured. Sensitivity S (cps MBq(-1)) in each acquisition is estimated as the product of the geometric G and the intrinsic efficiency η 0...
January 10, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28072574/motion-compensation-using-origin-ensembles-in-awake-small-animal-positron-emission-tomography
#8
John E Gillam, Georgios I Angelis, Andre Z Kyme, Steven R Meikle
In emission tomographic imaging, the stochastic origin ensembles algorithm provides unique information regarding the detected counts given the measured data. Precision in both voxel and region-wise parameters may be determined for a single data set based on the posterior distribution of the count density allowing uncertainty estimates to be allocated to quantitative measures. Uncertainty estimates are of particular importance in awake animal neurological and behavioral studies for which head motion, unique for each acquired data set, perturbs the measured data...
January 10, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28070776/computer-assisted-delineation-of-cerebral-infarct-from-diffusion-weighted-mri-using-gaussian-mixture-model
#9
Manas Kumar Nag, Subhranil Koley, Debarghya China, Anup Kumar Sadhu, Ravikanth Balaji, Siddharth Ghosh, Chandan Chakraborty
PURPOSE: Diffusion-weighted imaging (DWI) is a widely used medical imaging modality for diagnosis and monitoring of cerebral stroke. The identification of exact location of stroke lesion helps in perceiving its characteristics, an essential part of diagnosis and treatment planning. This task is challenging due to the typical shape of the stroke lesion. This paper proposes an efficient method for computer-aided delineation of stroke lesions from DWI images. METHOD: Proposed methodology comprises of three steps...
January 9, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28069515/a-new-method-of-content-based-medical-image-retrieval-and-its-applications-to-ct-imaging-sign-retrieval
#10
Ling Ma, Xiabi Liu, Yan Gao, Yanfeng Zhao, Xinming Zhao, Chunwu Zhou
This paper proposes a new method of content based medical image retrieval through considering fused, context-sensitive similarity. Firstly, we fuse the semantic and visual similarities between the query image and each image in the database as their pairwise similarities. Then, we construct a weighted graph whose nodes represent the images and edges measure their pairwise similarities. By using the shortest path algorithm over the weighted graph, we obtain a new similarity measure, context-sensitive similarity measure, between the query image and each database image to complete the retrieval process...
January 6, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28068539/one-step-synthesis-of-photoluminescent-carbon-dots-with-excitation-independent-emission-for-selective-bioimaging-and-gene-delivery
#11
Xudong Yang, Yang Wang, Xiran Shen, Chunyan Su, Jinghua Yang, Mingjun Piao, Fei Jia, Guanghui Gao, Long Zhang, Quan Lin
Photoluminescent carbon dots (C-dots), as new members of the quantum sized carbon analogues have attracted significant attention due to their unique size, less toxicity, good compatibility and relatively easy surface modification. In this work, we report a simple, low-cost and one-step hydrothermal carbonization approach to synthesize the positively charged C-dots using PEI and FA. From the photoluminescence (PL) measurements, the as-prepared C-dots exhibit good stability and intense PL with the high quantum yield (QY) at Ca...
December 24, 2016: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28068234/radiation-dose-dependent-hippocampal-atrophy-detected-with-longitudinal-volumetric-magnetic-resonance-imaging
#12
Tyler M Seibert, Roshan Karunamuni, Hauke Bartsch, Samar Kaifi, Anitha Priya Krishnan, Yoseph Dalia, Jeffrey Burkeen, Vyacheslav Murzin, Vitali Moiseenko, Joshua Kuperman, Nathan S White, James B Brewer, Nikdokht Farid, Carrie R McDonald, Jona A Hattangadi-Gluth
PURPOSE: After radiation therapy (RT) to the brain, patients often experience memory impairment, which may be partially mediated by damage to the hippocampus. Hippocampal sparing in RT planning is the subject of recent and ongoing clinical trials. Calculating appropriate hippocampal dose constraints would be improved by efficient in vivo measurements of hippocampal damage. In this study we sought to determine whether brain RT was associated with dose-dependent hippocampal atrophy. METHODS AND MATERIALS: Hippocampal volume was measured with magnetic resonance imaging (MRI) in 52 patients who underwent fractionated, partial brain RT for primary brain tumors...
February 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28066709/alterations-of-white-matter-structural-networks-in-patients-with-non-neuropsychiatric-systemic-lupus-erythematosus-identified-by-probabilistic-tractography-and-connectivity-based-analyses
#13
Man Xu, Xiangliang Tan, Xinyuan Zhang, Yihao Guo, Yingjie Mei, Qianjin Feng, Yikai Xu, Yanqiu Feng
PURPOSE: Systemic lupus erythematosus (SLE) is a chronic inflammatory female-predominant autoimmune disease that can affect the central nervous system and exhibit neuropsychiatric symptoms. In SLE patients without neuropsychiatric symptoms (non-NPSLE), recent diffusion tensor imaging studies showed white matter abnormalities in their brains. The present study investigated the entire brain white matter structural connectivity in non-NPSLE patients by using probabilistic tractography and connectivity-based analyses...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28063153/volumetric-assessment-of-alveolar-clefts-a-literature-review
#14
REVIEW
João Batista Blessmann Weber, Luciane de Macedo Menezes, Fabiane Azeredo, Luciano Schwartz Lessa Filho
OBJECTIVE: To conduct a review of the literature on methods for volumetric assessment of alveolar clefts and ascertain which methods are most precise to guide future research. METHODS: The PubMed and MEDLINE databases were searched for English-language reports of clinical and in vitro studies with detailed descriptions of imaging modality, sample characteristics, and method for measurement of alveolar cleft volume. RESULTS: The search strategy yielded 34 articles, of which 14 were selected for in-depth analysis...
January 7, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/28060285/preparation-and-in-vitro-characterization-of-dendrimer-based-contrast-agents-for-magnetic-resonance-imaging
#15
Serhat Gündüz, Tanja Savić, Đorđe Toljić, Goran Angelovski
Paramagnetic complexes of gadolinium(III) with acyclic or macrocyclic chelates are the most commonly used contrast agents (CAs) for magnetic resonance imaging (MRI). Their purpose is to enhance the relaxation rate of water protons in tissue, thus increasing the MR image contrast and the specificity of the MRI measurements. Current clinically approved contrast agents are low molecular weight molecules that are rapidly cleared from the body. The use of dendrimers as carriers of paramagnetic chelators can play an important role in the future development of more efficient MRI contrast agents...
December 4, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28060219/multicenter-study-of-adverse-events-after-intravenous-tissue-type-plasminogen-activator-treatment-of-acute-ischemic-stroke
#16
Hannah Fernandez-Gotico, Tiffany Lightfoot, Melissa Meighan
BACKGROUND AND PURPOSE: The approved treatment by the Food and Drug Administration for acute ischemic stroke is intravenous tissue-type plasminogen activator (IV tPA). After IV tPA administration, patients are monitored for adverse events using an American Heart Association/American Stroke Association guideline instituted in 1996. There is limited evidence describing the safest and most efficient method to monitor patients during the first 24 hours after tPA administration. Although the overall rates of adverse events have been reported, the time when patients may be at most risk for an event has not been studied...
February 2017: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
https://www.readbyqxmd.com/read/28059319/structural-optimization-for-remote-white-light-emitting-diodes-with-quantum-dots-and-phosphor-packaging-sequence-matters
#17
Bin Xie, Wei Chen, Junjie Hao, Dan Wu, Xingjian Yu, Yanhua Chen, Run Hu, Kai Wang, Xiaobing Luo
White light-emitting diodes (WLEDs) with quantum dots (QDs) and phosphor have attracted tremendous attentions due to their excellent color rendering ability. In the packaging process, QDs layer and phosphor-silicone layer tend to be separated to reduce the reabsorption losses, and to maintain the stability of QDs surface ligands. This study investigated the packaging sequence between QDs and phosphor on the optical and thermal performances of WLEDs. The output optical power and PL spectra were measured and analyzed, and the temperature fields were simulated and validated experimentally by infrared thermal imager...
December 26, 2016: Optics Express
https://www.readbyqxmd.com/read/28059290/self-calibration-single-lens-3d-video-extensometer-for-high-accuracy-and-real-time-strain-measurement
#18
Xinxing Shao, Mohammed Mokhtar Eisa, Zhenning Chen, Shuai Dong, Xiaoyuan He
The accuracy of strain measurement using a common optical extensometer with two-dimensional (2D) digital image correlation (DIC) is not sufficient for experimental applications due to the effect of out-of-plane motion. Although three-dimensional (3D) DIC can measure all three components of displacement without introducing in-plane displacement errors, 3D-DIC requires the stringent synchronization between two digital cameras and requires complicated system calibration of binocular stereovision, which makes the measurement rather inconvenient...
December 26, 2016: Optics Express
https://www.readbyqxmd.com/read/28058719/segmented-separable-footprint-projector-for-digital-breast-tomosynthesis-and-its-application-for-subpixel-reconstruction
#19
Jiabei Zheng, Jeffrey A Fessler, Heang-Ping Chan
PURPOSE: Digital forward and back projectors play a significant role in iterative image reconstruction. The accuracy of the projector affects the quality of the reconstructed images. Digital breast tomosynthesis (DBT) often uses the ray-tracing (RT) projector that ignores finite detector element size. This paper proposes a modified version of the separable footprint (SF) projector, called the segmented separable footprint (SG) projector, that calculates efficiently the Radon transform mean value over each detector element...
January 6, 2017: Medical Physics
https://www.readbyqxmd.com/read/28056761/quantifying-camouflage-how-to-predict-detectability-from-appearance
#20
Jolyon Troscianko, John Skelhorn, Martin Stevens
BACKGROUND: Quantifying the conspicuousness of objects against particular backgrounds is key to understanding the evolution and adaptive value of animal coloration, and in designing effective camouflage. Quantifying detectability can reveal how colour patterns affect survival, how animals' appearances influence habitat preferences, and how receiver visual systems work. Advances in calibrated digital imaging are enabling the capture of objective visual information, but it remains unclear which methods are best for measuring detectability...
January 6, 2017: BMC Evolutionary Biology
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