Lidia Yamamoto, Emilly Henrique Dos Santos, Lacyane Silva Pinto, Mussya Cisotto Rocha, Kelly Aparecida Kanunfre, Marcelo Genofre Vallada, Thelma Suely Okay
This narrative review summarizes the main aspects underlying the new coronavirus SARS-CoV-2, its epidemiology, pathophysiology, pointing to differences of SARS-CoV-2 main receptors ACE2, in terms of expression and the amount of soluble ACE2 in the circulation of children, men and women, and also in those with risk factors such as the smokers and pregnant women or presenting with comorbidities (diabetes, obesity, hypertension and other cardiovascular diseases, renal and CNS pre-existing diseases). Clinical manifestations in adults and children were also described, emphasizing the particularities already seen in children, regarding signs, symptoms, viral excretion time and the involvement of all organs and systems...
September 4, 2020: Revista do Instituto de Medicina Tropical de São Paulo