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Vulvodynia

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https://www.readbyqxmd.com/read/28065347/on-the-backs-of-giants-the-evolution-of-biofeedback-in-the-treatment-of-vulvodynia
#1
Amy Stein, Sara K Sauder
No abstract text is available yet for this article.
January 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28062309/a-local-inflammatory-renin-angiotensin-system-drives-sensory-axon-sprouting-in-provoked-vestibulodynia
#2
Zhaohui Liao, Anuradha Chakrabarty, Ying Mu, Aritra Bhattacherjee, Martha Goestch, Catherine M Leclair, Peter G Smith
: Vestibulodynia is a form of provoked vulvodynia characterized by profound tenderness, hyperinnervation, and frequently inflammation within well-defined areas of the human vestibule. Prior experiments in animal models show that inflammatory hypersensitivity and hyperinnervation occur in concert with establishment of a local renin-angiotensin system (RAS). Moreover, mechanical hypersensitivity and sensory axon sprouting are prevented by blocking effects of angiotensin II on AT2 receptors...
January 3, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28027132/the-mystery-of-vulvodynia-can-it-be-solved
#3
(no author information available yet)
No abstract text is available yet for this article.
January 2017: Nursing
https://www.readbyqxmd.com/read/28000024/current-practice-patterns-for-management-of-vulvodynia-in-the-united-states
#4
Lannah L Lua, Yvette Hollette, Prathamesh Parm, Gayle Allenback, Vani Dandolu
PURPOSE: To evaluate the current practice patterns for the management of vulvodynia in the United States (US) and to estimate healthcare costs related to this condition. METHODS: Truven MarketScan Commercial Claims and Encounters databases for years 2009-2013 were utilized for analysis. The study cohort included women, 18 years or older, with a diagnosis of vulvodynia (ICD-9 625.70), who had been continuously enrolled for 360 days from the date of diagnosis. Measures included the most common prescriptions, primary procedures, associated diagnoses, as well as net healthcare costs...
December 20, 2016: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/27984345/vulvodynia-what-we-know-and-where-we-should-be-going
#5
Logan M Havemann, David R Cool, Pascal Gagneux, Michael P Markey, Jerome L Yaklic, Rose A Maxwell, Ashvin Iyer, Steven R Lindheim
OBJECTIVE: The aim of the study was to review the current nomenclature and literature examining microbiome cytokine, genomic, proteomic, and glycomic molecular biomarkers in identifying markers related to the understanding of the pathophysiology and diagnosis of vulvodynia (VVD). MATERIALS AND METHODS: Computerized searches of MEDLINE and PubMed were conducted focused on terminology, classification, and "omics" variations of VVD. Specific MESH terms used were VVD, vestibulodynia, metagenomics, vaginal fungi, cytokines, gene, protein, inflammation, glycomic, proteomic, secretomic, and genomic from 2001 to 2016...
December 15, 2016: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/27922897/the-mystery-of-vulvodynia-can-it-be-solved
#6
Helen E Harrison
No abstract text is available yet for this article.
January 2017: Nursing
https://www.readbyqxmd.com/read/27872029/association-between-infertility-and-sexual-dysfunction-in-men-and-women
#7
REVIEW
Michael H Berger, Marisa Messore, Alexander W Pastuszak, Ranjith Ramasamy
INTRODUCTION: The relation between infertility and sexual dysfunction can be reciprocal. Causes of sexual dysfunction that affect fertility include erectile dysfunction, Peyronie's disease (abnormal penile curvature), low libido, ejaculatory disorders in men, and genito-pelvic pain/penetration disorder (GPPPD) and low sexual desire in women. AIM: To review the association between infertility and sexual dysfunction and discuss current management strategies to address sexual disorders in couples with infertility...
October 2016: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/27872003/primary-and-secondary-provoked-vestibulodynia-a-review-of-overlapping-and-distinct-factors
#8
REVIEW
Caroline F Pukall
INTRODUCTION: A common subtype of vulvodynia is provoked vestibulodynia (PVD), characterized by severe pain upon contact to the vaginal entrance. Some researchers have further delineated the PVD group based on pain onset (primary vs secondary PVD, referred to as PVD1 and PVD2, respectively). AIM: This study aims to review available evidence regarding sociodemographic variables, pain characteristics, medical history and examination findings, quantitative sensory testing, genetic markers, psychosocial/sexual/relationship function, treatment outcome, and brain imaging in women with PVD1 and PVD2...
January 2016: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/27860096/vulvodynia-a-painful-condition-an-inflammatory-process
#9
K R Wylie
No abstract text is available yet for this article.
January 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27853523/recent-advances-in-understanding-provoked-vestibulodynia
#10
REVIEW
Ahinoam Lev-Sagie, Steven S Witkin
Vulvodynia refers to pain in the vulva of at least 3 months' duration in the absence of a recognized underlying cause. Provoked, localized vestibulodynia is the term used to describe superficial pain confined to the vulvar vestibule, provoked by touch. This review will focus on provoked vestibulodynia with regard to its suggested causative factors and will discuss the role of inflammation, vulvovaginal infections, mucosal nerve fiber proliferation, hormonal associations, central pain mechanisms, pelvic floor muscle dysfunction, and genetic factors...
2016: F1000Research
https://www.readbyqxmd.com/read/27789257/does-degree-of-vulvar-sensitivity-predict-vulvodynia-characteristics-and-prognosis
#11
Barbara D Reed, Melissa A Plegue, Sioban D Harlow, Hope K Haefner, Ananda Sen
: Although women with vulvodynia typically have increased vulvar sensitivity, data on characteristics associated with the degree of vulvar sensitivity are lacking. We measured vulvar sensitivity using cotton swab test and vulvodolorimeter among a subset of 335 women, aged younger than 70 years, in the longitudinal Woman to Woman Health Study. Comparing the vulvodynia screening results from their online/paper survey to that at the time of the examination, 42 women had ongoing vulvodynia, 66 had a recent remission, 22 control participants had a recent onset of vulvodynia, and 205 control participants remained asymptomatic...
October 24, 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/27780702/catechol-o-methyltransferase-gene-polymorphism-and-vulvar-pain-in-women-with-vulvodynia
#12
Insiyyah Y Patanwala, Georgine Lamvu, William J Ledger, Kathryn Witzeman, Richard Marvel, Andrea Rapkin, Ann Marie Bongiovanni, Jessica Feranec, Steven S Witkin
BACKGROUND: The underlying causes of vulvar pain in women with vulvodynia remain poorly understood. Catechol-O-methyltransferase, an enzyme that metabolizes catecholamines, is a neuromodulator that is involved with perception and sensitivity to pain. The catechol-O-methyltransferase gene is polymorphic, and a single nucleotide polymorphism is associated with low activity and heightened pain sensitivity. The variant allele that encodes this polymorphism commonly is called the "L allele" because of its low enzyme activity as opposed to the normal H (high activity) allele...
October 22, 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27780177/the-vulvar-pain-assessment-questionnaire-inventory
#13
Emma Dargie, Ronald R Holden, Caroline F Pukall
Millions suffer from chronic vulvar pain (ie, vulvodynia). Vulvodynia represents the intersection of 2 difficult subjects for health care professionals to tackle: sexuality and chronic pain. Those with chronic vulvar pain are often uncomfortable seeking help, and many who do so fail to receive proper diagnoses. The current research developed a multidimensional assessment questionnaire, the Vulvar Pain Assessment Questionnaire (VPAQ) inventory, to assist in the assessment and diagnosis of those with vulvar pain...
December 2016: Pain
https://www.readbyqxmd.com/read/27764759/6-methoxyflavanone-attenuates-mechanical-allodynia-and-vulvodynia-in-the-streptozotocin-induced-diabetic-neuropathic-pain
#14
Shehla Akbar, Fazal Subhan, Nasiara Karim, Muhammad Shahid, Nisar Ahmad, Gowhar Ali, Wajahat Mahmood, Khwaja Fawad
BACKGROUND: Diabetic neuropathy is the most prevalent, persistent and debilitating complication of diabetes mellitus often coupled with vulvodynia that may present as an isolated symptom or as a part of constellation of other neuropathic abnormalities. OBJECTIVE: Flavonoids have selective affinity for GABA receptors and 6-methoxyflavanone (6-MeOF) is a positive allosteric modulator of GABA responses at human recombinant GABAA receptors. GABAergic and opioidergic system inhibition have been shown to facilitate neuropathic pain...
December 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27757050/new-topical-treatment-of-vulvodynia-based-on-the-pathogenetic-role-of-cross-talk-between-nociceptors-immunocompetent-cells-and-epithelial-cells
#15
J M Keppel Hesselink, D J Kopsky, N Sajben
Topical treatments of localized neuropathic pain syndromes in general are mostly neglected, mainly due to the fact that most pain physicians expect that a topical formulation needs to result in a transdermal delivery of the active compounds. On the basis of the practical experience, this study brings forth a new, somewhat neglected element of the vulvodynia pathogenesis: the cross talk between the nerve endings of nociceptors, the adjacent immunocompetent cells, and vaginal epithelial cells. Insight into this cross talk during a pathogenic condition supports the treatment of vulvodynia with topical (compounded) creams...
2016: Journal of Pain Research
https://www.readbyqxmd.com/read/27753704/multimodal-vulvar-and-peripheral-sensitivity-among-women-with-vulvodynia-a-case-control-study
#16
Barbara D Reed, Ananda Sen, Sioban D Harlow, Hope K Haefner, Richard H Gracely
OBJECTIVE: To assess differences in vulvar and peripheral sensitivity between women with and without vulvodynia. METHODS: Women with vulvodynia (n = 41) and age-matched controls (n = 43) seen in the outpatient setting were evaluated via surveys, clinical examination, and multimodal sensory testing (pressure, heat, cold, vibration, and electrical stimulation). The relationships between sensitivity to various sensory modalities and case/control status, as well as by vulvodynia subgroups, were assessed using logistic regression...
January 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/27673373/vulvodynia-when-a-paradigm-challenges-the-management
#17
Fabrizio Bogliatto, Michela Miletta
No abstract text is available yet for this article.
January 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/27670706/clinicians-perspectives-and-experiences-regarding-maternity-care-in-women-with-vulvodynia
#18
Kelly B Smith, Leslie A Sadownik, Rosemary Basson, Jordanna Isaacson, Lori A Brotto
OBJECTIVE: To assess clinicians' frequency of and comfort with provision of maternity care for women with vulvodynia, their beliefs and practices regarding delivery mode, and frequency of maternal requests for Caesarean section (CS). METHODS: We invited physicians and midwives to complete a questionnaire assessing their frequency of contact with pregnant women with vulvodynia; their level of comfort providing antenatal, intrapartum, and postpartum care for these women; whether they believed that vulvodynia is an indication for elective CS and the frequency of making this recommendation; and the number of patients with vulvodynia who strongly requested CS...
September 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/27633925/identifying-fibromyalgia-subgroups-using-cluster-analysis-relationships-with-clinical-variables
#19
Y-R Yim, K-E Lee, D-J Park, S-H Kim, S-S Nah, J H Lee, S-K Kim, Y-A Lee, S-J Hong, H-S Kim, H-S Lee, H A Kim, C-I Joung, S-H Kim, S-S Lee
BACKGROUND: Patients with fibromyalgia (FM) exhibit significant clinical heterogeneity, in terms of physical, social and psychological functions, as well as therapeutic responses. Here, we examined FM patients in terms of pain, physical, social and psychological variables to identify clinical subgroups that may be predictive of treatment patterns. METHODS: A total of 313 FM patients were interviewed using a structured questionnaire that included sociodemographic data, current or past FM symptoms and current use of relevant medications...
September 15, 2016: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/27614384/-interest-of-infiltration-of-impar-node-in-rebel-vulvodynia-about-a-series-of-8-cases
#20
C Cardaillac, S Ploteau, J-J Labat, A Levesque, T Riant
INTRODUCTION: Vulvodynia is a common and debilitating disease, for which treatments are often of limits efficacy. As the Impar node receives nociceptive afferents from pelvis and perineum, it is a potential therapeutic target to treat pain in this region. The objective of the study was to evaluate the relevance of ropivacaine Impar node infiltration in patients suffering from rebel vulvodyny. METHODS: This was a retrospective, single-center study. The Impar node infiltrations were performed by a single operator in eight patients suffering from rebel vulvodynia...
December 2016: Progrès en Urologie
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