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Vulvodynia

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https://www.readbyqxmd.com/read/27872029/association-between-infertility-and-sexual-dysfunction-in-men-and-women
#1
REVIEW
Michael H Berger, Marisa Messore, Alexander W Pastuszak, Ranjith Ramasamy
INTRODUCTION: The relation between infertility and sexual dysfunction can be reciprocal. Causes of sexual dysfunction that affect fertility include erectile dysfunction, Peyronie's disease (abnormal penile curvature), low libido, ejaculatory disorders in men, and genito-pelvic pain/penetration disorder (GPPPD) and low sexual desire in women. AIM: To review the association between infertility and sexual dysfunction and discuss current management strategies to address sexual disorders in couples with infertility...
October 2016: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/27872003/primary-and-secondary-provoked-vestibulodynia-a-review-of-overlapping-and-distinct-factors
#2
REVIEW
Caroline F Pukall
INTRODUCTION: A common subtype of vulvodynia is provoked vestibulodynia (PVD), characterized by severe pain upon contact to the vaginal entrance. Some researchers have further delineated the PVD group based on pain onset (primary vs secondary PVD, referred to as PVD1 and PVD2, respectively). AIM: This study aims to review available evidence regarding sociodemographic variables, pain characteristics, medical history and examination findings, quantitative sensory testing, genetic markers, psychosocial/sexual/relationship function, treatment outcome, and brain imaging in women with PVD1 and PVD2...
January 2016: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/27860096/vulvodynia-a-painful-condition-an-inflammatory-process
#3
K R Wylie
No abstract text is available yet for this article.
November 16, 2016: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27853523/recent-advances-in-understanding-provoked-vestibulodynia
#4
REVIEW
Ahinoam Lev-Sagie, Steven S Witkin
Vulvodynia refers to pain in the vulva of at least 3 months' duration in the absence of a recognized underlying cause. Provoked, localized vestibulodynia is the term used to describe superficial pain confined to the vulvar vestibule, provoked by touch. This review will focus on provoked vestibulodynia with regard to its suggested causative factors and will discuss the role of inflammation, vulvovaginal infections, mucosal nerve fiber proliferation, hormonal associations, central pain mechanisms, pelvic floor muscle dysfunction, and genetic factors...
2016: F1000Research
https://www.readbyqxmd.com/read/27789257/does-degree-of-vulvar-sensitivity-predict-vulvodynia-characteristics-and-prognosis
#5
Barbara D Reed, Melissa A Plegue, Sioban D Harlow, Hope K Haefner, Ananda Sen
: Although women with vulvodynia typically have increased vulvar sensitivity, data on characteristics associated with the degree of vulvar sensitivity are lacking. We measured vulvar sensitivity by cotton swab test and vulvodolorimeter among a subset of 335 women, ages <70 years, in the longitudinal Woman to Woman Health Study. Comparing the vulvodynia screening results from their online/paper survey to that at the time of the examination, 42 cases had ongoing vulvodynia, 66 cases had a recent remission, 22 controls now had a recent onset of vulvodynia, and 205 controls remained asymptomatic...
October 24, 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/27780702/catechol-o-methyltransferase-gene-polymorphism-and-vulvar-pain-in-women-with-vulvodynia
#6
Insiyyah Y Patanwala, Georgine Lamvu, William J Ledger, Kathryn Witzeman, Richard Marvel, Andrea Rapkin, Ann Marie Bongiovanni, Jessica Feranec, Steven S Witkin
BACKGROUND: The underlying causes of vulvar pain in women with vulvodynia remain poorly understood. Catechol-O-methyltransferase, an enzyme that metabolizes catecholamines, is a neuromodulator that is involved with perception and sensitivity to pain. The catechol-O-methyltransferase gene is polymorphic, and a single nucleotide polymorphism is associated with low activity and heightened pain sensitivity. The variant allele that encodes this polymorphism commonly is called the "L allele" because of its low enzyme activity as opposed to the normal H (high activity) allele...
October 22, 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27780177/the-vulvar-pain-assessment-questionnaire-inventory
#7
Emma Dargie, Ronald R Holden, Caroline F Pukall
Millions suffer from chronic vulvar pain (ie, vulvodynia). Vulvodynia represents the intersection of 2 difficult subjects for health care professionals to tackle: sexuality and chronic pain. Those with chronic vulvar pain are often uncomfortable seeking help, and many who do so fail to receive proper diagnoses. The current research developed a multidimensional assessment questionnaire, the Vulvar Pain Assessment Questionnaire (VPAQ) inventory, to assist in the assessment and diagnosis of those with vulvar pain...
December 2016: Pain
https://www.readbyqxmd.com/read/27764759/6-methoxyflavanone-attenuates-mechanical-allodynia-and-vulvodynia-in-the-streptozotocin-induced-diabetic-neuropathic-pain
#8
Shehla Akbar, Fazal Subhan, Nasiara Karim, Muhammad Shahid, Nisar Ahmad, Gowhar Ali, Wajahat Mahmood, Khwaja Fawad
BACKGROUND: Diabetic neuropathy is the most prevalent, persistent and debilitating complication of diabetes mellitus often coupled with vulvodynia that may present as an isolated symptom or as a part of constellation of other neuropathic abnormalities. OBJECTIVE: Flavonoids have selective affinity for GABA receptors and 6-methoxyflavanone (6-MeOF) is a positive allosteric modulator of GABA responses at human recombinant GABAA receptors. GABAergic and opioidergic system inhibition have been shown to facilitate neuropathic pain...
October 17, 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27757050/new-topical-treatment-of-vulvodynia-based-on-the-pathogenetic-role-of-cross-talk-between-nociceptors-immunocompetent-cells-and-epithelial-cells
#9
J M Keppel Hesselink, D J Kopsky, N Sajben
Topical treatments of localized neuropathic pain syndromes in general are mostly neglected, mainly due to the fact that most pain physicians expect that a topical formulation needs to result in a transdermal delivery of the active compounds. On the basis of the practical experience, this study brings forth a new, somewhat neglected element of the vulvodynia pathogenesis: the cross talk between the nerve endings of nociceptors, the adjacent immunocompetent cells, and vaginal epithelial cells. Insight into this cross talk during a pathogenic condition supports the treatment of vulvodynia with topical (compounded) creams...
2016: Journal of Pain Research
https://www.readbyqxmd.com/read/27753704/multimodal-vulvar-and-peripheral-sensitivity-among-women-with-vulvodynia-a-case-control-study
#10
Barbara D Reed, Ananda Sen, Sioban D Harlow, Hope K Haefner, Richard H Gracely
OBJECTIVE: To assess differences in vulvar and peripheral sensitivity between women with and without vulvodynia. METHODS: Women with vulvodynia (n = 41) and age-matched controls (n = 43) seen in the outpatient setting were evaluated via surveys, clinical examination, and multimodal sensory testing (pressure, heat, cold, vibration, and electrical stimulation). The relationships between sensitivity to various sensory modalities and case/control status, as well as by vulvodynia subgroups, were assessed using logistic regression...
October 7, 2016: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/27673373/vulvodynia-when-a-paradigm-challenges-the-management
#11
Fabrizio Bogliatto, Michela Miletta
No abstract text is available yet for this article.
September 26, 2016: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/27670706/clinicians-perspectives-and-experiences-regarding-maternity-care-in-women-with-vulvodynia
#12
Kelly B Smith, Leslie A Sadownik, Rosemary Basson, Jordanna Isaacson, Lori A Brotto
OBJECTIVE: To assess clinicians' frequency of and comfort with provision of maternity care for women with vulvodynia, their beliefs and practices regarding delivery mode, and frequency of maternal requests for Caesarean section (CS). METHODS: We invited physicians and midwives to complete a questionnaire assessing their frequency of contact with pregnant women with vulvodynia; their level of comfort providing antenatal, intrapartum, and postpartum care for these women; whether they believed that vulvodynia is an indication for elective CS and the frequency of making this recommendation; and the number of patients with vulvodynia who strongly requested CS...
September 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/27633925/identifying-fibromyalgia-subgroups-using-cluster-analysis-relationships-with-clinical-variables
#13
Y-R Yim, K-E Lee, D-J Park, S-H Kim, S-S Nah, J H Lee, S-K Kim, Y-A Lee, S-J Hong, H-S Kim, H-S Lee, H A Kim, C-I Joung, S-H Kim, S-S Lee
BACKGROUND: Patients with fibromyalgia (FM) exhibit significant clinical heterogeneity, in terms of physical, social and psychological functions, as well as therapeutic responses. Here, we examined FM patients in terms of pain, physical, social and psychological variables to identify clinical subgroups that may be predictive of treatment patterns. METHODS: A total of 313 FM patients were interviewed using a structured questionnaire that included sociodemographic data, current or past FM symptoms and current use of relevant medications...
September 15, 2016: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/27614384/-interest-of-infiltration-of-impar-node-in-rebel-vulvodynia-about-a-series-of-8-cases
#14
C Cardaillac, S Ploteau, J-J Labat, A Levesque, T Riant
INTRODUCTION: Vulvodynia is a common and debilitating disease, for which treatments are often of limits efficacy. As the Impar node receives nociceptive afferents from pelvis and perineum, it is a potential therapeutic target to treat pain in this region. The objective of the study was to evaluate the relevance of ropivacaine Impar node infiltration in patients suffering from rebel vulvodyny. METHODS: This was a retrospective, single-center study. The Impar node infiltrations were performed by a single operator in eight patients suffering from rebel vulvodynia...
December 2016: Progrès en Urologie
https://www.readbyqxmd.com/read/27607347/sexual-pain-in-women-exploring-the-manifestations-of-vaginismus-versus-vulvodynia
#15
Anna Ghizzani, Piersante Sestini
BACKGROUND: Sexual pain is frequently seen in gynecological practice as a consequence of lower tract pathology. When organic causes are ruled out we must think of a functional pain syndrome such as the genital pelvic pain/penetration disorder (GPPD) whose diagnostic criteria are defined by the Diagnostic and Statistic Manual-5; these criteria describe both vaginismus and vulvodynia that present themselves with somewhat different clinical dimensions and require different treatments. Even if gynecologists do not usually manage functional sexual pain, they can easily reach the differential diagnosis through the sexual pain anamnesis because some symptoms are specific of one or the other condition...
September 8, 2016: Minerva Ginecologica
https://www.readbyqxmd.com/read/27574494/vulvodynia-and-irritable-bowel-syndrome-treated-with-an-elimination-diet-a-case-report
#16
Jessica Drummond, Deborah Ford, Stephanie Daniel, Tara Meyerink
BACKGROUND: A 28-y-old athletic woman was diagnosed with vulvodynia and long-term irritable bowel syndrome (IBS) and was treated successfully with an elimination diet. CASE/INTERVENTION: In the course of 6 mo of nutrition therapy utilizing an elimination diet, specific foods triggering abdominal bloating and pain, and vulvovaginal pain were identified. In the course of treatment, the nutrition and supplement program instituted for this patient allowed her to return to her prior functional level without pain (including sexual activity) and resolution of her IBS...
August 2016: Integrative Medicine
https://www.readbyqxmd.com/read/27568225/effect-of-vestibulectomy-for-intractable-vulvodynia
#17
Christopher J Kliethermes, Mitul Shah, Susan Hoffstetter, Jeffrey A Gavard, Andrew Steele
STUDY OBJECTIVE: To assess the effectiveness of vestibulectomy in treating vulvodynia for patients with inadequate response to vulvar care guidelines and medical management. DESIGN: Retrospective case series (Canadian Task Force classification II-2). PATIENTS: All patients who underwent a vestibulectomy from 2004 to 2013 for vulvodynia. INTERVENTIONS: All patients in this study underwent a vestibulectomy. MEASUREMENTS AND MAIN RESULTS: In this study we analyzed 31 patients' overall reported pain scores and Q-tip test scores before and after vestibulectomy...
August 25, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27548558/committee-opinion-no-673-persistent-vulvar-pain
#18
(no author information available yet)
Persistent vulvar pain is a complex disorder that frequently is frustrating to the patient and the clinician. It can be difficult to treat and rapid resolution is unusual, even with appropriate therapy. Vulvar pain can be caused by a specific disorder or it can be idiopathic. Idiopathic vulvar pain is classified as vulvodynia. Although optimal treatment remains unclear, consider an individualized, multidisciplinary approach to address all physical and emotional aspects possibly attributable to vulvodynia. Specialists who may need to be involved include sexual counselors, clinical psychologists, physical therapists, and pain specialists...
September 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27548552/committee-opinion-no-673-summary-persistent-vulvar-pain
#19
(no author information available yet)
Persistent vulvar pain is a complex disorder that frequently is frustrating to the patient and the clinician. It can be difficult to treat and rapid resolution is unusual, even with appropriate therapy. Vulvar pain can be caused by a specific disorder or it can be idiopathic. Idiopathic vulvar pain is classified as vulvodynia. Although optimal treatment remains unclear, consider an individualized, multidisciplinary approach to address all physical and emotional aspects possibly attributable to vulvodynia. Specialists who may need to be involved include sexual counselors, clinical psychologists, physical therapists, and pain specialists...
September 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27544818/a-role-for-bradykinin-signaling-in-chronic-vulvar-pain
#20
Megan L Falsetta, David C Foster, Collynn F Woeller, Stephen J Pollock, Adrienne D Bonham, Constantine G Haidaris, Richard P Phipps
: Chronic vulvar pain is alarmingly common in women of reproductive age and is often accompanied by psychological distress, sexual dysfunction, and a significant reduction in quality of life. Localized provoked vulvodynia (LPV) is associated with intense vulvar pain concentrated in the vulvar vestibule (area surrounding vaginal opening). To date, the origins of vulvodynia are poorly understood, and treatment for LPV manages pain symptoms, but does not resolve the root causes of disease...
August 18, 2016: Journal of Pain: Official Journal of the American Pain Society
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