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Ahmed M A Altibi, Raed A H Qarajeh, Telmo A B Belsuzarri, Walid Maani, Tareq M A Kanaan
BACKGROUND: Hydatid disease is a life-threatening parasitic infestation caused by Echinococcus granulosus. Infection with E. granulosus typically results in the formation of hydatid cysts in the liver, lungs, kidney, and spleen. Primary intracranial hydatid cyst disease is extremely rare. Here, we are reporting an unusual case of Echinococcus, where the only identifiable lesion was a hydatid cyst in the brain without liver or lung involvement. We are also providing a description for the surgical technique used to remove the cyst, highlighting the possible surgical pitfalls...
2016: Surgical Neurology International
Daniela Denk, Belgees Boufana, Nicholas J Masters, Mark F Stidworthy
Tapeworms of the genus Echinococcus reside in the small intestine of a number of carnivorous species, predominantly canids. In enzootic areas, hydatidosis caused by taeniid metacestodes can present a significant problem in accidental intermediate hosts, including humans. Whereas the United Kingdom is currently considered free of Echinococcus multilocularis, Echinococcus granulosus sensu stricto (s.s.) and Echinococcus equinus are endemic in the UK and have been reported in a variety of captive mammals. The presentation of echinoccocosis in non-human primates widely parallels disease in humans, and public health concerns are related to the four genera, E...
March 15, 2016: Veterinary Parasitology
A Lopez-Bernus, M Belhassen-García, A Carpio-Perez, L Perez Del Villar, A Romero-Alegria, V Velasco-Tirado, A Muro, J Pardo-Lledias, M Cordero-Sánchez, M Alonso-Sardón
Cystic echinococcosis (CE) remains an important health problem in many areas of the world, including the Mediterranean region. We performed a retrospective study of cases reported from 1998 to 2012 in order to review and update the epidemiology of this disease in a highly endemic area situated in western Spain. A total of 471 patients were diagnosed with hydatid disease. Of these cases, 55·8% were male, with an average age of 62·3 ± 19·5 years. More importantly, 1·5% of patients were children, and 20·5% were aged <45 years...
November 2015: Epidemiology and Infection
Guodong Lü, Wenbao Zhang, Jianhua Wang, Yunfeng Xiao, Jun Zhao, Jianqin Zhao, Yimin Sun, Chuanshan Zhang, Junhua Wang, Renyong Lin, Hui Liu, Fuchun Zhang, Hao Wen
Cystic echinoccocosis (CE) is a neglected zoonosis that is caused by the dog-tapeworm Echinococcus granulosus. The disease is endemic worldwide. There is an urgent need for searching effective drug for the treatment of the disease. In this study, we sequenced a cDNA library constructed using RNA isolated from oncospheres, protoscoleces, cyst membrane and adult worms of E. granulosus. A total of 9065 non-redundant or unique sequences were obtained and spotted on chips as uniEST probes to profile the gene expression in protoscoleces of E...
December 2014: Molecular and Biochemical Parasitology
Emilia Virginia Noormahomed, Noémia Nhacupe, Carmen Mascaró-Lazcano, Manuel Natane Mauaie, Titos Buene, Carlos Abel Funzamo, Constance Ann Benson
BACKGROUND: Helminthic infections are highly endemic in Mozambique, due to limited access to healthcare and resources for disease prevention. Data on the subclinical prevalence of these diseases are scarce due to the fact that an immunological and imaging diagnosis is not often available in endemic areas. We conducted a cross-sectional study on HIV1(+) patients from Beira city in order to determine the seroprevalence of cysticercosis, schistosomiasis, toxocariasis and echinoccocosis and its possible interaction with HIV infection...
September 2014: PLoS Neglected Tropical Diseases
P Comrnejo-Juárez, A Espinosa-Altamirano, M Ibarra-del-Río, I Pacheco-Bravo, P Volkow-Fernández
Echinococcosis is a parasitic disease that involves dogs as definitive host and sheep as intermediate host. Humans become infected incidentally through fecal-oral contact, particularly in the course of playful and close contact with an infected dog. Mexico is considered a region that is virtually free of cystic echinoccocosis. This manuscript describes two cases that were referred to a tertiary-care oncology hospital with a diagnosis of cancer. In one case, the presumptive diagnosis was liver cancer because abdominal ultrasonography revealed a low-density mass in the right hepatic lobe...
March 2013: West Indian Medical Journal
Christine M Budke, Hélène Carabin, Patrick C Ndimubanzi, Hai Nguyen, Elizabeth Rainwater, Mary Dickey, Rachana Bhattarai, Oleksandr Zeziulin, Men-Bao Qian
A systematic literature review of cystic echinoccocosis (CE) frequency and symptoms was conducted. Studies without denominators, original data, or using one serological test were excluded. Random-effect log-binomial models were run for CE frequency and proportion of reported symptoms where appropriate. A total of 45 and 25 articles on CE frequency and symptoms met all inclusion criteria. Prevalence of CE ranged from 1% to 7% in community-based studies and incidence rates ranged from 0 to 32 cases per 100,000 in hospital-based studies...
June 2013: American Journal of Tropical Medicine and Hygiene
Joanna Giebultowicz, Malgorzata Polanska-Plachta, Piotr Wroczynski, Piotr Zaborowski, Jerzy A Polanski
BACKGROUND: An increasing number of publications are suggesting that galectin-3 (Gal-3) and soluble cadherin fragments, such as E-cadherin (sE-CAD) and N-cadherin (sN-CAD), may be considered as cancer markers. Despite the promising results of the studies, there are no data concerning their levels in the plasma of echinococcosis patients. In most cases, echinoccocosis affects the liver, and its symptoms and disease course are very similar to those of liver cancer. The aim of the present study was to observe whether echinococcosis affects the concentration of soluble sN-CAD, sE-CAD fragments and Gal-3 in plasma and to determine which of them could be considered reliable liver cancer markers for further research...
2012: Diagnostic Pathology
Dordde M Culafić, Mirko D Kerkez, Dragana D Mijac, Nebojsa S Lekić, Vitomir I Ranković, Dragana D Lekić, Zoran Lj Dordević
AIM: The aim of our study was to demonstrate clinical manifestations and diagnostic methods of splenic echinococcosis and suggest surgical approach. METHODS: The study involved 20 patients of previously diagnosed spleen echinococcosis. A diagnosis was made for each patient, based on medical history, biochemical and serological tests, physical examination and abdominal ultrasonography. All the patients received a CT scan of the abdomen. These patients had undergone the following surgery procedures: total splenectomy 13 (60%), and spleen-preserving surgery 7 (35%) patients...
2010: Scandinavian Journal of Gastroenterology
Regula Theurillat, Wolfgang Thormann
An assay for the simultaneous determination of the enantiomers of hydroxymebendazole (OH-MBZ) and hydroxyaminomebendazole (OH-AMBZ) together with aminomebendazole (AMBZ) in human plasma is described for the first time. It is based upon liquid-liquid extraction at alkaline pH from 0.5 mL plasma followed by analysis of the reconstituted extract by CE with reversed polarity in the presence of a 50 mM, pH 4.2 acetate buffer containing 15 mg/mL sulfated beta-CD as chiral selector. For all compounds, detection limits are between 0...
January 2008: Journal of Separation Science
M Conchedda, E Gabriele, G Bortoletti
The present report focuses on the ability of cystic echinoccocosis metacestode to survive for a long time, despite host immunity, by developing avoidance strategies. The tactics believed to come into play, ranging from intrinsic parasitic factors to host-related mechanisms, are briefly discussed and the importance of studies on experimental models is highlighted particularly in relation to furthering the theoretical understanding of the dynamic equilibrium between host and parasite, and to the feasibility of practical approaches in controlling the disease by artificial manipulation of the immunoregulatory mechanisms...
December 2004: Parassitologia
S Bresson-Hadni, D A Vuitton
Human echinococcoses, cystic echinococcosis and alveolar echinococcosis are due to infections with the cestodes Echinococcus granulosus and E. multilocularis, respectively. Both zoonoses share a prolonged latency period before clinical presentation. However their evolution is fairly different: that of a begin tumor of the liver or lung for cystic echinoccocosis, and that of a slowly developing malignant tumor of the liver for alveolar echinoccocosis, with subsequent invasion of liver vessels and bile ducts and metastatic dissemination...
December 1, 2001: La Revue du Praticien
C Monange, D Clément, J P Miguet, J F Bosset
No abstract text is available yet for this article.
July 1973: Les Cahiers de Médecine
T M Kariev, E S Islambekov, D T Maksumov
Clinical observations concerning the surgical treatment of multiple pulmonary echinococcosis in 54 patients are set forth in the paper. Various surgical interventions were carried out upon 46 patients: 16--for unilateral multiple echinicoccosis, 30--for bilateral multiple echinococcosis; in 8 patients pulmonary echinococcosis was combined with liver injury. From the authors' experience the surgical treatment of multiple pulmonary echinococcosis is an effective method. Good clinico-roentgenologic results were found in 44 out of 46 patients operated upon...
February 1979: Vestnik Khirurgii Imeni I. I. Grekova
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