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Microvascular imaging

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https://www.readbyqxmd.com/read/28731055/choroidal-excavation-in-choroidal-osteoma-complicated-by-choroidal-neovascularization
#1
L Pierro, A Marchese, M Gagliardi, U Introini, M Battaglia Parodi, G Casalino, F Bandello
PurposeTo describe multimodal imaging features of choroidal osteoma (CO) complicated by choroidal neovascularization (CNV) and focal choroidal excavation (FCE).MethodsPatients presenting with CO and CNV between January and October 2016 were considered for this study. Diagnosis of CO was confirmed by ultrasound examination. All patients underwent multimodal imaging including optical coherence tomography (OCT), swept-source OCT angiography (DRI OCT Triton, Topcon, Inc., Tokyo, Japan) and fluorescein angiography (Spectralis HRA+OCT; Heidelberg Engineering, Heidelberg, Germany)...
July 21, 2017: Eye
https://www.readbyqxmd.com/read/28730399/optical-coherence-tomography-angiography-findings-in-susac-s-syndrome-a-case-report
#2
Rodolfo Mastropasqua, Lisa Toto, Alfonso Senatore, Alessandro D'Uffizi, Piergiorgio Neri, Cesare Mariotti, Marica Tina Maccarone, Luca Di Antonio
PURPOSE: To report clinical features of Susac's syndrome (SS) using optical coherence tomography angiography (OCTA). METHODS: Case report. RESULTS: A 25-year-old Caucasian female with a history of non-pulsatile migraine, tinnitus, and verbal apraxia complaining of peripheral scotoma in left eye due to branch retinal arteriole occlusion (BRAO) was diagnosed as having SS after audiometric test, brain magnetic resonance imaging, and multimodal retinal imaging...
July 20, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28728985/adjuvant-hepatic-arterial-infusion-chemotherapy-is-beneficial-for-selective-patients-with-hepatocellular-carcinoma-undergoing-surgical-treatment
#3
Jui-Hu Hsiao, Cheng-Chung Tsai, Tsung-Jung Liang, Chia-Ling Chiang, Huei-Lung Liang, I-Shu Chen, Yu-Chia Chen, Po-Ming Chang, Nan-Hua Chou, Being-Whey Wang
BACKGROUND: Recurrence rate after curative surgical resection of Hepatocellular carcinoma (HCC) remains high. Postoperative hepatic arterial infusion chemotherapy (HAIC) has been suggested to improve survival. This study is to investigate the efficacy of HAIC in the patients with poor tumor factors such as vascular invasion or multiplicity. METHODS: From 2006 to 2014, 221 patients with HCC undergoing hepatectomy and pathologically staged as ≧ T2 (American Joint Committee on Cancer TNM staging system, 7th edition) were included...
July 17, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28728187/in-vivo-microvascular-pattern-of-solitary-juxtapapillary-capillary-hemangioma-on-oct-angiography
#4
M B Thirumalesh, Astha Jain, Sumeet Agrawal, K Bhujang Shetty
Juxtapapillary capillary hemangioma (JCH) is a vascular hamartoma. Fluorescein fundus angiography aids in diagnosis. The vascular morphology of this tumor has not been documented with optical coherence tomography angiography (OCTA), a new, noninvasive diagnostic modality that provides high-resolution images of vascular pattern based on blood flow in the retina and choroid. Although mainly a clinical diagnosis, OCTA helps in studying the intrinsic vascularity of the tumor and helps in differentiating it from other vascular tumors...
July 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28723846/value-of-fractal-analysis-of-optical-coherence-tomography-angiography-in-various-stages-of-diabetic-retinopathy
#5
Suruchi Bhardwaj, Edmund Tsui, Sarwar Zahid, Emma Young, Nitish Mehta, Steven Agemy, Patricia Garcia, Richard B Rosen, Joshua A Young
PURPOSE: To use fractal dimensional analysis to investigate retinal vascular disease patterns in patients with diabetic retinopathy using spectral domain optical coherence tomography angiography. METHODS: A retrospective study was conducted which included 49 eyes from 26 control subjects and 58 eyes from 35 patients known to have diabetic retinopathy. Of the 58 eyes with known retinopathy, 31 were categorized as nonproliferative diabetic retinopathy (13 mild, 9 moderate, and 9 severe) and 27 were categorized as proliferative diabetic retinopathy...
July 18, 2017: Retina
https://www.readbyqxmd.com/read/28718319/medical-modeling-for-precision-ulna-reconstruction-using-a-microvascular-fibula-free-flap
#6
Michael Alperovich, Jonathan M Bekisz, Vishal D Thanik
BACKGROUND: Despite the growing use of medical modeling in other surgical specialties, its utilization in extremity reconstruction has remained limited. METHODS: We present the application of medical modeling for ulna reconstruction using a microvascular fibula free flap. RESULTS: Following a motor vehicle accident, the patient suffered segmental loss of the right radius and ulna with concomitant forearm soft tissue and muscle loss. Using medical modeling, imaging from the unaffected contralateral forearm and lower extremity was used to plan a reconstruction that restored the anatomic length and orientation of the ulna...
January 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28716007/silent-myocarditis-in-systemic-sclerosis-detected-by-cardiovascular-magnetic-resonance-using-lake-louise-criteria
#7
Sophie Mavrogeni, Loukia Koutsogeorgopoulou, Georgia Karabela, Efthymios Stavropoulos, Gikas Katsifis, John Raftakis, Sotiris Plastiras, Michel Noutsias, George Markousis-Mavrogenis, Genovefa Kolovou
BACKGROUND: Systemic sclerosis (SSc) is an autoimmune disease characterized by microvascular abnormalities, inflammation and fibrosis. We hypothesized that myocarditis may be diagnosed in asymptomatic SSc, undergoing routine cardio-vascular magnetic resonance (CMR) for fibrosis assessment, using the Lake Louise criteria: T2 ratio, early (EGE) and late gadolinium enhanced (LGE) images. METHODS: Eighty-two asymptomatic SSc, diagnosed according to American College of Rheumatology criteria, aged 43 ± 5 yrs...
July 17, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28709153/age-reduces-microvascular-function-in-the-leg-independent-of-physical-activity
#8
Anne Tonson, Kayle E Noble, Ronald A Meyer, Mitchell R Rozman, Kevin T Foley, Jill M Slade
The microvasculature is critical in the control of blood flow. Aging and reduced physical activity (PA) may both decrease microvascular function. PURPOSE: The primary aim was to evaluate the influence of age on microvascular function in adults with similar PA levels. Secondary aims were to assess the reliability of muscle functional magnetic resonance imaging in older adults (OA) and the relationship between PA and microvascular function in OA. METHODS: Microvascular blood-oxygen-level dependent (BOLD) responses were measured in young adults (YA, n = 12, mean ± SD age = 21 ± 1 yr old, PA = 239 ± 73 × 10 counts per day) and OA (n = 13, 64 ± 4 yr old, PA = 203 ± 48 × 10 counts per day)...
August 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28705067/pancreatic-elastography-from-acoustic-radiation-force-impulse-imaging-for-evaluation-of-diabetic-microangiopathy
#9
Yu He, Hui Wang, Xiao Ping Li, Juan-Juan Zheng, Chun-Xiang Jin
OBJECTIVE: The purposes of this study were to compare pancreatic shear-wave velocity (SWV) in subjects with and those without diabetic microvascular complications and to investigate the feasibility of pancreatic SWV in evaluating diabetic microangiopathy. SUBJECTS AND METHODS: SWV measurements were prospectively performed in 115 patients with diabetes mellitus and 115 healthy persons by use of acoustic radiation force impulse imaging. Patients with diabetes were divided into subgroups with and without microangiopathy...
July 13, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28704481/renal-auto-transplantation-promotes-cortical-microvascular-network-remodeling-in-a-preclinical-porcine-model
#10
Souleymane Maïga, Geraldine Allain, Thierry Hauet, Jerome Roumy, Edouard Baulier, Michel Scepi, Manuel Dierick, Luc Van Hoorebeke, Patrick Hannaert, Franck Guy, Frederic Favreau
The vascular network is a major target of ischemia-reperfusion, but has been poorly investigated in renal transplantation. The aim of this study was to characterize the remodeling of the renal vascular network that follows ischemia-reperfusion along with the most highly affected cortex section in a preclinical renal transplantation model. There were two experimental groups. The first was a grafted kidney group consisting of large white pigs for which the left kidney was harvested, cold flushed, preserved for 24 h in the University of Wisconsin's preservation solution, and then auto-transplanted (n = 5); the right kidney was removed to mimic the situation of human kidney transplantation...
2017: PloS One
https://www.readbyqxmd.com/read/28699046/optical-clearing-and-fluorescence-deep-tissue-imaging-for-3d-quantitative-analysis-of-the-brain-tumor-microenvironment
#11
Tonny Lagerweij, Sophie A Dusoswa, Adrian Negrean, Esther M L Hendrikx, Helga E de Vries, Jeroen Kole, Juan J Garcia-Vallejo, Huibert D Mansvelder, W Peter Vandertop, David P Noske, Bakhos A Tannous, René J P Musters, Yvette van Kooyk, Pieter Wesseling, Xi Wen Zhao, Thomas Wurdinger
BACKGROUND: Three-dimensional visualization of the brain vasculature and its interactions with surrounding cells may shed light on diseases where aberrant microvascular organization is involved, including glioblastoma (GBM). Intravital confocal imaging allows 3D visualization of microvascular structures and migration of cells in the brain of mice, however, with limited imaging depth. To enable comprehensive analysis of GBM and the brain microenvironment, in-depth 3D imaging methods are needed...
July 11, 2017: Angiogenesis
https://www.readbyqxmd.com/read/28697558/comparative-analysis-of-cortical-microinfarcts-and-microbleeds-using-3-0-tesla-postmortem-magnetic-resonance-images-and-histopathology
#12
Atsushi Niwa, Yuichiro Ii, Akihiro Shindo, Ko Matsuo, Hidehiro Ishikawa, Akira Taniguchi, Shinichi Takase, Masayuki Maeda, Hajime Sakuma, Hiroyasu Akatsu, Yoshio Hashizume, Hidekazu Tomimoto
Microvascular lesions including cortical microinfarctions (CMIs) and cerebral lobar microbleeds (CMBs) are usually caused by cerebral amyloid angiopathy (CAA) in the elderly and are correlated with cognitive decline. However, their radiological-histopathological coincidence has not been revealed systematically with widely used 3-Tesla (3T) magnetic resonance imaging (MRI). The purpose of the present study is to delineate the histopathological background corresponding to MR images of these lesions. We examined formalin-fixed 10-mm thick coronal brain blocks from 10 CAA patients (five were also diagnosed with Alzheimer's disease, three with dementia with Lewy bodies, and two with CAA only) with dementia and six non CAA patients with neurodegenerative disease...
July 5, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28695406/quantification-of-intramyocardial-blood-volume-with-99m-tc-rbc-spect-ct-imaging-a-preclinical-study
#13
Hassan Mohy-Ud-Din, Nabil E Boutagy, John C Stendahl, Zhen W Zhuang, Albert J Sinusas, Chi Liu
BACKGROUND: Currently, there is no established non-invasive imaging approach to directly evaluate myocardial microcirculatory function in order to diagnose microvascular disease independent of co-existing epicardial disease. In this work, we developed a methodological framework for quantification of intramyocardial blood volume (IMBV) as a novel index of microcirculatory function with SPECT/CT imaging of (99m)Tc-labeled red blood cells (RBCs). METHODS: Dual-gated myocardial SPECT/CT equilibrium imaging of (99m)Tc-RBCs was performed on twelve canines under resting conditions...
July 10, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28693502/the-role-of-thrombectomy-and-diffusion-weighted-imaging-with-mri-in-post-transplant-renal-vein-thrombosis-a-case-report
#14
Paraish Misra, Anish Kirpalani, General Leung, Paraskevi A Vlachou, Jason Y Lee, Serge Jothy, Jeffrey Zaltzman, Darren A Yuen
BACKGROUND: Surgical thrombectomy in the context of acute renal vein thrombosis (RVT) post-transplantation has had limited success, with considerable variation in the surgical techniques used. Unfortunately, it is usually followed by allograft nephrectomy within a few days if rapid allograft recovery does not ensue. We report a case of acute RVT in which nephrectomy was not performed despite a prolonged requirement for dialysis post-thrombectomy, but with recovery of renal function 2 weeks later...
July 10, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28693176/flexible-magnifying-endoscopy-with-narrow-band-imaging-for-the-diagnosis-of-uterine-cervical-tumors-a-cooperative-study-among-gastrointestinal-endoscopists-and-gynecologists-to-explore-a-novel-microvascular-classification-system
#15
Noriko Nishiyama, Kenji Kanenishi, Hirohito Mori, Hideki Kobara, Shintaro Fujihara, Taiga Chiyo, Nobuya Kobayashi, Tae Matsunaga, Maki Ayaki, Tatsuo Yachida, Ayako Fujimori, Makoto Oryu, Chiaki Tenkumo, Megumi Ishibashi, Uiko Hanaoka, Toshiyuki Hata, Yumi Miyai, Kyuichi Kadota, Reiji Haba, Tsutomu Masaki
Narrow band imaging with magnifying endoscopy (NBI-ME), which is useful for the assessment of micro-vessels, has excellent diagnostic potential for early gastrointestinal epithelial neoplasia. Conventional diagnostic tools for uterine cervical epithelial tumors are still unsatisfactory. An accurate diagnostic tool for uterine cervical epithelial tumors is required to preserve the reproductive ability of young women with uterine cervical tumors. Flexible NBI-ME was performed in patients with cervical squamous cell lesions that required further examinations based on their Pap smear results (cytology ≥ low-grade squamous intraepithelial lesion) at Kagawa University Hospital between April 2014 and April 2015...
July 2017: Oncology Letters
https://www.readbyqxmd.com/read/28689341/painful-spasms-in-facial-masticatory-and-motor-ocular-muscles-reversed-after-microvascular-decompression-of-a-neurovascular-conflict-at-brainstem
#16
Tania-Mihaela Idriceanu, Marc Sindou
The authors present a case of a 42-year-old female admitted for disabling complex and atypical bilateral facial spasms associated with painful masticatory and motor ocular dystonic movements, difficult to fit in the definition of any known cranio-facial dyskinesias. MRI showed a left PICA loop invaginated into the brainstem, considered responsible of an hyperactive disorder of the brainstem nuclei neighboring the conflict. After microvascular decompression, the patient made a full recovery with complete disappearance of the paroxystic phenomena...
July 8, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28687846/comparison-of-the-retinal-microvascular-density-between-open-angle-glaucoma-and-nonarteritic-anterior-ischemic-optic-neuropathy
#17
Chun-Hsiu Liu, Wei-Chi Wu, Ming-Hui Sun, Ling-Yuh Kao, Yung-Sung Lee, Henry Shen-Lih Chen
Purpose: To compare optical coherence tomography angiography (OCT-A) retinal vasculature measurements between nonarteritic anterior ischemic optic neuropathy (NAION) and open angle glaucoma (OAG) with altitudinal hemifield visual field defects. Methods: This retrospective cross-sectional study included 10 NAION eyes and 16 OAG eyes, both demonstrating hemifield visual field defects, and 27 normal eyes serving as controls. The peripapillary and macular OCT-A scans were acquired...
July 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28685679/clinical-approach-to-diabetic-cardiomiopathy-a-review-of-human-studies
#18
Roberto Tarquini, Laura Pala, Simona Brancati, Giulia Vannini, Salvatore De Cosmo, Gianluigi Mazzoccoli, Carlo Maria Rotella
BACKGROUND: Diabetic Cardiomiopathy (DC) has been defined as a distinct entity characterized by the presence of diastolic or systolic cardiac dysfunction in a diabetic patient in the absence of other causes for Cardiomiopathy, such as coronary artery disease (CAD), hypertension (HTN), or valvular heart disease. Diabetes affects every organ in the body and cardiovascular disease accounts for two-thirds of the mortality in the diabetic population. Diabetes-related heart disease occurs in the form of coronary artery disease (CAD), cardiac autonomic neuropathy or DC...
July 5, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28685434/computational-simulation-of-tumor-hypoxia-based-on-in-vivo-microvasculature-assessed-in-a-dorsal-skin-window-chamber
#19
Lina Xu, Peter Vaupel, Siwei Bai, Bjoern Menze, Kuangyu Shi
Malignant growth usually leads to the depletion of oxygen (O2) supply in most solid tumors. Hypoxia can cause resistance to standard radiotherapy, some chemotherapy and immunotherapy. Furthermore, it can also trigger malignant progression by modulating gene expression and inducing genetic instability. The relationship between microvasculature, perfusion and tumor hypoxia has been intensively studied and many computational simulations have been developed to model tissue O2 transport. Usually simplified 2D phantoms are used to investigate tumor hypoxia and it is assumed that vessels are perpendicular to the region of interest and randomly distributed across the domain...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28683162/an-observational-study-of-microcirculation-in-dialysis-patients-and-kidney-transplant-recipients
#20
Yu Chang Yeh, Anne Chao, Chih-Yaun Lee, Chen-Tse Lee, Chi-Chuan Yeh, Chih-Min Liu, Meng-Kun Tsai
BACKGROUND: Microcirculatory dysfunction contributes to acute and chronic kidney diseases. To the best of our knowledge, no study has compared differences in microcirculation among healthy volunteers, dialysis patients, and kidney transplant recipients. MATERIALS AND METHODS: Sublingual microcirculation was examined using sidestream dark field imaging and was compared among 90 healthy volunteers, 40 dialysis patients, and 40 kidney transplant recipients. The gender effect on microcirculation and the correlations among the microcirculation parameters, age, body mass index, heart rate, and blood pressure were analyzed...
July 6, 2017: European Journal of Clinical Investigation
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