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Microvascular imaging

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https://www.readbyqxmd.com/read/29677375/characteristics-of-retinal-structural-and-microvascular-alterations-in-early-type-2-diabetic-patients
#1
Qi Chen, Fan Tan, Yufei Wu, Xiran Zhuang, Chaoming Wu, Yuheng Zhou, Yingzi Li, Dan Cheng, Jianhua Wang, Fan Lu, Meixiao Shen
Purpose: To investigate early retinal structural and microvascular changes in patients with type 2 diabetes mellitus (DM) and to analyze relationships among the retinal structure, microvasculature, and choroid. Methods: Seventy-seven patients with type 2 DM (40 with no diabetic retinopathy [DR], 37 with nonproliferative diabetic retinopathy [NPDR]), and 34 control subjects were enrolled. Spectral-domain optical coherence tomography, operating in radial 18-line mode, obtained macular images of the eight intraretinal layers and the choroid...
April 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29675295/combination-of-structural-and-vascular-optical-coherence-tomography-for-differentiating-oral-lesions-of-mice-in-different-carcinogenesis-stages
#2
Ping-Hisen Chen, Chien-Hsien Wu, Yi-Fen Chen, Yi-Chen Yeh, Bo-Han Lin, Kuo-Wei Chang, Pei-Yu Lai, Ming-Chih Hou, Ching-Liang Lu, Wen-Chuan Kuo
Differentiating between early malignancy and benign lesions in oral cavities is difficult using current optical tools. As has been shown in previous studies, microvascular changes in squamous epithelium can be regarded as a key marker for diagnosis. We propose the combination of structural and vascular optical coherence tomography (OCT) imaging for the investigation of disease related changes. Progressive thickness changes of epithelium and the destruction of underlying lamina propria was observed during cancer development in a 4- nitroquinoline-1-oxide (4NQO) mouse model...
April 1, 2018: Biomedical Optics Express
https://www.readbyqxmd.com/read/29675082/susac-s-syndrome-retinocochleocerebral-vasculopathy-follow-up-of-a-pediatric-patient
#3
Zeynep Selen Karalok, Birce Dilge Taskin, Alev Guven, Cemile Atilgan Ucgul, Omer Faruk Aydin
Susac's syndrome (SS) is a triad of encephalopathy, branch retinal artery occlusion (BRAO), and sensorineural hearing loss as a result of microvascular occlusions of the brain, retina, and inner ear. It is also a disorder of autoimmune endotheliopathy. SS usually affects young women between the age of 20 and 40 years. SS can be misdiagnosed as multiple sclerosis (MS) or acute disseminated encephalomyelitis (ADEM) because of similar findings. A 15-year-old girl presented in June 2015 with vomiting and severe headache...
October 2017: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/29672783/-smartphone-based-thermography-for-perforator-localisation-in-microvascular-breast-reconstruction
#4
Leonard Walle, Hisham Fansa, Onno Frerichs
BACKGROUND: Thermography permits non-invasive examination and presentation of cutaneous temperature differences. When planning microvascular flaps, thermography may illustrate these differences and may portray patterns of blood circulation near to perforators. As an additional tool, thermography may enhance quality and diversity in free flaps. PATIENTS AND METHODS: In this prospective study, we examined 10 patients with 13 free DIEP-flaps for breast reconstruction...
April 2018: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/29672768/microsurgical-resection-of-a-meningioma-at-the-entrance-of-dorello-s-canal-causing-vi-cranial-nerve-compression-2-dimensional-operative-video
#5
Abdulrahman Alturki, Alejandro Enriquez-Marulanda, Raghav Gupta, Ajith J Thomas, Christopher S Ogilvy
We describe the case of a 73-yr-old female patient with a 2-yr history of diplopia that has progressively become worse. Physical examination revealed a right VI cranial nerve (CN) palsy. Magnetic resonance imaging and angiography showed a dolichoectatic basilar artery near the VI CN. A suboccipital craniectomy was performed, initially with the intention to perform a microvascular decompression; however, a red mass was encountered at the entrance of the right Dorello's canal that was compressing the VI CN. Complete resection of the lesion was done and decompression of the nerve was accomplished...
April 17, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29670096/motion-model-ultrasound-localization-microscopy-for-preclinical-and-clinical-multiparametric-tumor-characterization
#6
Tatjana Opacic, Stefanie Dencks, Benjamin Theek, Marion Piepenbrock, Dimitri Ackermann, Anne Rix, Twan Lammers, Elmar Stickeler, Stefan Delorme, Georg Schmitz, Fabian Kiessling
Super-resolution imaging methods promote tissue characterization beyond the spatial resolution limits of the devices and bridge the gap between histopathological analysis and non-invasive imaging. Here, we introduce motion model ultrasound localization microscopy (mULM) as an easily applicable and robust new tool to morphologically and functionally characterize fine vascular networks in tumors at super-resolution. In tumor-bearing mice and for the first time in patients, we demonstrate that within less than 1 min scan time mULM can be realized using conventional preclinical and clinical ultrasound devices...
April 18, 2018: Nature Communications
https://www.readbyqxmd.com/read/29667428/optical-coherence-tomography-angiography-characterization-of-acute-and-late-stage-purtscher-retinopathy
#7
Pedro Gil, Miguel Raimundo, João P Marques, João Póvoa, Rufino Silva
PURPOSE: To report a case of Purtscher retinopathy imaged with optical coherence tomography angiography. METHODS: Case-report. Left eye fundoscopic examination in a 21-year old male after a road traffic accident with chest compression revealed multiple peri-papillary cotton-wool spots and intra- and pre-retinal hemorrhages. A diagnosis of Purtscher retinopathy was assumed. RESULTS: In both the superficial and deep retinal plexuses, acute stage optical coherence tomography angiography identified multiple irregular areas of capillary non-perfusion that extended beyond the clinically visible peri-papillary cotton-wool spots...
April 1, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29666969/three-case-reports-of-radiation-induced-glioblastoma-after-complete-remission-of-acute-lymphoblastic-leukemia
#8
Takumi Kajitani, Masayuki Kanamori, Ryuta Saito, Yuko Watanabe, Hiroyoshi Suzuki, Mika Watanabe, Shigeo Kure, Teiji Tominaga
Radiation therapy is sometimes performed to control intracranial acute lymphoblastic leukemia (ALL), but may lead to radiation-induced malignant glioma. The clinical, radiological, histological, and molecular findings are described of three cases of radiation-induced glioblastoma after the treatment for ALL. They received radiation therapy at age 6-8 years. The latency from radiation therapy to the onset of radiation-induced glioblastoma was 5-10 years. Magnetic resonance imaging demonstrated diffuse lesions with multiple small enhanced lesions in all cases...
April 17, 2018: Brain Tumor Pathology
https://www.readbyqxmd.com/read/29665789/idiopathic-basal-ganglia-calcification-associated-with-cerebral-micro-infarcts-a-case-report
#9
Takuma Nishimoto, Fumiaki Oka, Hideyuki Ishihara, Mizuya Shinoyama, Michiyasu Suzuki
BACKGROUND: Idiopathic basal ganglia calcification (IBGC) is a rare neurodegenerative disorder characterized by symmetric intracranial calcium deposition. We report a patient with IBGC associated with cerebral infarction due to impairment of cerebrovascular reactivity based on single-photon emission computed tomography (SPECT) with acetazolamide challenge. CASE PRESENTATION: A 66-year-old male presented with right conjugate deviation, right hemiparesis and total aphasia due to a convulsive seizure...
April 17, 2018: BMC Neurology
https://www.readbyqxmd.com/read/29663478/superb-microvascular-imaging-of-the-median-nerve-in-carpal-tunnel-syndrome-an-electrodiagnostic-and-ultrasonographic-study
#10
Ali Yavuz Karahan, Serdar Arslan, Banu Ordahan, Suleyman Bakdik, Timur Ekiz
OBJECTIVE: To evaluate intraneural blood flow of the median nerve using superb microvascular imaging (SMI) and power Doppler ultrasonography (PDUS), and to examine their correlation with electroneuromyography in patients with carpal tunnel syndrome (CTS). METHODS: A cross-sectional survey was used, and the study was conducted in the research unit of a training and research hospital. Patients diagnosed with CTS according to electroneuromyography studies were included in the study...
April 16, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29662873/permissive-hypercapnia-results-in-decreased-functional-vessel-density-in-the-skin-of-extremely-low-birth-weight-infants
#11
Alexandra Francoise Puchwein-Schwepcke, Kristina Schottmayer, Zuzana Mormanová, Jens Dreyhaupt, Orsolya Genzel-Boroviczeny, Ulrich H Thome
Background: Ventilator-induced lung injury with subsequent bronchopulmonary dysplasia remains an important issue in the care of extremely low-birth-weight infants. Permissive hypercapnia has been proposed to reduce lung injury. Hypercapnia changes cerebral perfusion, but its influence on the peripheral microcirculation is unknown. Methods: Data were collected from 12 infants, who were randomized to a permissive high PCO2 target group (HTG) or a control group (CG)...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29660911/the-effects-of-different-remote-ischemic-conditioning-on-ischemia-induced-failure-of-microvascular-circulation-in-humans
#12
Muzaffer Akkoca, Suzan Emel Usanmaz, Serhat Tokgöz, Cüneyt Köksoy, Emine Demirel-Yilmaz
BACKGROUND: Intermittent ischemia in remote tissues can be applied before ischemic injury, during ischemic injury or at the beginning of reperfusion of an index organ ischemia. The aim of this study was to investigate the effect of Remote Ischemic Conditioning (RIC) of the leg on changes in ischemia-induced the microvascular functions of the arm. MATERIAL AND METHODS: Ischemic microvascular injury was induced by arm ischemia (20 min) and reperfusion in healthy, nonsmoker, male volunteers (ischemia group-ISC, n: 9)...
April 13, 2018: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/29659161/neurovascular-relations-of-the-trigeminal-nerve-in-asymptomatic-individuals-studied-with-high-resolution-three-dimensional-magnetic-resonance-imaging
#13
Fernando Ruiz-Juretschke, Laín H González-Quarante, Roberto García-Leal, Vicente Martínez de Vega
Neurovascular compression (NVC) is considered the main cause of classic trigeminal neuralgia (TN) and may be surgically addressed with microvascular decompression (MVD). Preoperative high-resolution three-dimensional magnetic resonance has proven a reliable tool to diagnose NVC in patients with refractory TN undergoing MVD. However there is still scarce data regarding the rate, degree and characteristics of neurovascular compression in asymptomatic individuals. This article describes the vascular relations of the trigeminal nerve in the cerebellopontine angle (CPA) in 100 subjects without known TN studied with 3...
April 16, 2018: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/29658771/diagnostic-performances-of-superb-microvascular-imaging-shear-wave-elastography-and-shape-index-in-pediatric-lymph-nodes-categorisation-a-comparative-study
#14
Zuhal Bayramoglu, Emine Caliskan, Zeynep Karakas, Deniz Tugcu, Serap Karaman, Ayper Somer, Manolya Kara, Ferhan Akıcı, Ibrahim Adaletli
OBJECTIVE: To determine the diagnostic utility of a vascularity index via superb microvascular imaging in lymph nodes of children with malignant lymphoma and acute lymphadenitis compared to normal lymph nodes. METHODS: We performed a retrospective study for multiparametric lymph node (LN) evaluation. Malignant lymphoma diagnosed via histopathological examination and lymph nodes receiving an acute lymphadenitis diagnosis based on clinical and laboratory findings constituted the study subgroups...
April 16, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29649987/multimodal-imaging-of-foveoschisis-and-macular-pseudohole-associated-with-gyrate-atrophy-a-family-report
#15
Imène Zhioua Braham, Imen Ammous, Rim Maalej, Majdi Boukari, Ilhem Mili Boussen, Khalil Errais, Raja Zhioua
BACKGROUND: To report the results of multimodal imaging of a biochemically confirmed case of a family with gyrate atrophy (GA) associated with foveoschisis and macular pseudohole. CASE PRESENTATION: Two sisters presented to us with progressive bilateral decreased vision. The 26-year old sister had a best corrected visual acuity (BCVA) of 20/32 in the right eye (RE) and 20/100 in the left eye (LE). Dilated fundus examination revealed multiple bilateral chorioretinal atrophy areas in the midperipheral and peripheral retina...
April 12, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29649559/ultrafast-doppler-for-neonatal-brain-imaging
#16
REVIEW
Charlie Demene, Jérôme Mairesse, Jérôme Baranger, Mickael Tanter, Olivier Baud
The emergence of functional neuroimaging has dramatically accelerated our understanding of the human mind. The advent of functional Magnetic Resonance Imaging paved the way for the next decades' major discoveries in neuroscience and today remains the "gold standard" for deep brain imaging. Recent improvements in imaging technology have been somewhat limited to incremental innovations of mature techniques instead of breakthroughs. Recently, the use of ultrasonic plane waves transmitted at ultrafast frame rates was shown to highly increase Doppler ultrasound sensitivity to blood flows in small vessels in rodents...
April 9, 2018: NeuroImage
https://www.readbyqxmd.com/read/29649166/tumor-associated-macrophages-and-mast-cells-positive-to-tryptase-are-correlated-with-angiogenesis-in-surgically-treated-gastric-cancer-patients
#17
Giuseppe Sammarco, Cosmo Damiano Gadaleta, Valeria Zuccalà, Emre Albayrak, Rosa Patruno, Pietro Milella, Rosario Sacco, Michele Ammendola, Girolamo Ranieri
Mast cells and macrophages can play a role in tumor angiogenesis by stimulating microvascular density (MVD). The density of mast cells positive to tryptase (MCDPT), tumor-associated macrophages (TAMs), and MVD were evaluated in a series of 86 gastric cancer (GC) tissue samples from patients who had undergone potential curative surgery. MCDPT, TAMs, and MVD were assessed in tumor tissue (TT) and in adjacent normal tissue (ANT) by immunohistochemistry and image analysis. Each of the above parameters was correlated with the others and, in particular for TT, with important clinico-pathological features...
April 12, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29628453/multiple-acquired-portosystemic-shunts-secondary-to-primary-hypoplasia-of-the-portal-vein-in-a-cat
#18
Satoko Sugimoto, Shingo Maeda, Masaya Tsuboi, Kohei Saeki, James K Chambers, Tomohiro Yonezawa, Kenjiro Fukushima, Reina Fujiwara, Kazuyuki Uchida, Hajime Tsujimoto, Naoaki Matsuki, Koichi Ohno
A 6-year 5-month-old spayed female Scottish Fold cat presented with a one-month history of gait abnormalities, increased salivation, and decreased activity. A blood test showed hyperammonemia and increased serum bile acids. Imaging tests revealed multiple shunt vessels indicating acquired portosystemic shunt. Histopathologic analysis of liver biopsy showed features consistent with liver hypoperfusion, such as a barely recognizable portal vein, increased numbers of small arterioles, and diffuse vacuolar degeneration of hepatocytes...
April 9, 2018: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/29626679/gamma-knife-radiosurgery-for-trigeminal-neuralgia-associated-with-osteogenesis-imperfecta
#19
Yoshiyasu Iwai, Kenichi Ishibashi, Kazuhiro Yamanaka
OBJECTIVE: Trigeminal neuralgia is a rare feature of basilar impression, a complication of osteochondrodysplastic disorders. Microvascular decompression is difficult in medically refractory cases. Gamma knife radiosurgery (GKS) is effective for classical trigeminal neuralgia and we first applied this GKS for a patient suffering from trigeminal neuralgia with basilar impression complicated by osteogenesis imperfecta. CLINICAL PRESENTATION: An 18-year-old man with typeⅠosteogenesis imperfecta presented with a 2-year history of typical left trigeminal neuralgia affecting the ophthalmic, maxillary, and mandibular nerves...
April 4, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29625719/endocytoscopy-for-in-situ-real-time-histology-of-oral-mucosal-lesions
#20
I Miyamoto, N Yada, K Osawa, I Yoshioka
This study investigated the utility of endocytoscopy, a novel emerging endoscopic system, for in situ real-time histology of oral mucosal lesions. Endocytoscopy involves the use of a contact light microscopy system with 380-fold magnification. With the development of endoscopic instruments, it has become possible to observe the abnormal microvascular and capillary patterns of tumour cells. The resolution of the endoscopic image is improved in situ, and a more detailed diagnosis is possible. In this study, endocytoscopy along with other diagnostic modalities was used in nine patients...
April 3, 2018: International Journal of Oral and Maxillofacial Surgery
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