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https://www.readbyqxmd.com/read/28934798/clinical-course-of-cervical-percutaneous-epidural-neuroplasty-in-single-level-cervical-disc-disease-with-12-month-follow-up
#1
Chang Hyun Oh, Gyu Yeul Ji, Dong Ah Shin, Pyung Goo Cho, Seung Hwan Yoon
BACKGROUND: Cervical disc disease is a common and occasionally disabling condition, occurring as a natural consequence of aging in the vast majority of the adult population. Percutaneous epidural neuroplasty (PEN) has been used to deliver highly concentrated drugs for chronic neck pain and to prevent scarring in cases refractory to conventional epidural blocks. However, the clinical course after PEN in cervical disc disease is not well-documented. OBJECTIVE: The purpose of this study was to evaluate the efficacy of cervical PEN for single-level cervical disc disease...
September 2017: Pain Physician
https://www.readbyqxmd.com/read/28934121/current-status-of-early-blight-resistance-in-tomato-an-update
#2
REVIEW
Pragya Adhikari, Yeonyee Oh, Dilip R Panthee
Early blight (EB) is one of the dreadful diseases of tomato caused by several species of Alternaria including Alternaria linariae (which includes A. solani and A. tomatophila), as well as A. alternata. In some instances, annual economic yield losses due to EB have been estimated at 79%. Alternaria are known only to reproduce asexually, but a highly-virulent isolate has the potential to overcome existing resistance genes. Currently, cultural practices and fungicide applications are employed for the management of EB due to the lack of strong resistant cultivars...
September 21, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28933564/%C3%AE-glucosidase-inhibition-by-flavonoids-an-in-vitro-and-in-silico-structure-activity-relationship-study
#3
Carina Proença, Marisa Freitas, Daniela Ribeiro, Eduardo F T Oliveira, Joana L C Sousa, Sara M Tomé, Maria J Ramos, Artur M S Silva, Pedro A Fernandes, Eduarda Fernandes
α-Glucosidase inhibitors are described as the most effective in reducing post-prandial hyperglycaemia (PPHG) from all available anti-diabetic drugs used in the management of type 2 diabetes mellitus. As flavonoids are promising modulators of this enzyme's activity, a panel of 44 flavonoids, organised in five groups, was screened for their inhibitory activity of α-glucosidase, based on in vitro structure-activity relationship studies. Inhibitory kinetic analysis and molecular docking calculations were also applied for selected compounds...
December 2017: Journal of Enzyme Inhibition and Medicinal Chemistry
https://www.readbyqxmd.com/read/28918821/explaining-the-continuum-of-social-participation-among-older-adults-in-singapore-from-closed-doors-to-active-ageing-in-multi-ethnic-community-settings
#4
Su Aw, Gerald Koh, Yeon Ju Oh, Mee Lian Wong, Hubertus J M Vrijhoef, Susana Concordo Harding, Mary Ann B Geronimo, Cecilia Yoon Fong Lai, Zoe J L Hildon
OBJECTIVES: This study aims to identify and explain the continuum in which older people in Singapore participate in community and social life, highlighting the influence of culture and policy context on social participation. METHODS: Using an ethnographic approach in a neighbourhood (n=109), we conducted focus groups with older adults of different ethnicities, exploring experiences of social participation. Next, participants took 50 photographs relating to 'lives of elders', showcasing the socio-ecological context that influenced social participation...
August 2017: Journal of Aging Studies
https://www.readbyqxmd.com/read/28906349/intestinal-obstruction-due-to-kaposiform-hemangioendothelioma-in-a-1-month-old-infant-a-case-report
#5
Joong Kee Youn, Shin-Hoo Park, Ji-Won Han, Chaeyoun Oh, Hyun-Young Kim, Sung-Eun Jung
RATIONALE: Kaposiform hemangioendothelioma (KHE) is an aggressive vascular tumor, mainly occurring in infants and young children and previously reported cases were mainly cutaneous or visceral form. Intestinal kaposiform hemangioma was first reported in 2012. Intestinal type KHE showed better prognosis if the lesion was limited in the gastrointestinal tract and coagulopathy was not accompanied. Since the number of reported cases is small, further study for treatment options and prognosis need to be done...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28905533/short-term-evaluation-of-a-comprehensive-education-program-including-inhaler-training-and-disease-management-on-chronic-obstructive-pulmonary-disease
#6
Kwang Ha Yoo, Wou Young Chung, Joo Hun Park, Sung Chul Hwang, Tae Eun Kim, Min Jung Oh, Dae Ryong Kang, Chin Kook Rhee, Hyoung Kyu Yoon, Tae Hyung Kim, Deog Kyeom Kim, Yong Bum Park, Sang Ha Kim, Ho Kee Yum
BACKGROUND: Proper education regarding inhaler usage and optimal management of chronic obstructive pulmonary disease (COPD) is essential for effectively treating patients with COPD. This study was conducted to evaluate the effects of a comprehensive education program including inhaler training and COPD management. METHODS: We enlisted 127 patients with COPD on an outpatient basis at 43 private clinics in Korea. The patients were educated on inhaler usage and disease management for three visits across 2 weeks...
September 1, 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28901791/determinants-of-1-year-survival-in-critically-ill-acute-leukemia-patients-a-grrr-oh-study
#7
Márcio Tavares, Virginie Lemiale, Djamel Mokart, Frédéric Pène, Etienne Lengliné, Achille Kouatchet, Julien Mayaux, François Vincent, Martine Nyunga, Fabrice Bruneel, Antoine Rabbat, Christine Lebert, Pierre Perez, Anne-Pascale Meert, Dominique Benoit, Michael Darmon, Elie Azoulay
Acute leukemia (AL) is the most common hematological malignancy requiring intensive care unit (ICU) management. Data on long-term survival are limited. This is a post hoc analysis of the prospective multicenter data from France and Belgium: A Groupe de Recherche Respiratoire en Réanimation Onco-Hématologique [A Research Group on Acute Respiratory Failure in Onco-Hematological Patients (French)] Study, to identify determinants of 1-year survival in critically ill AL patients. A total of 278 patients were admitted in the 17 participating ICUs...
September 13, 2017: Leukemia & Lymphoma
https://www.readbyqxmd.com/read/28882264/development-of-a-multilevel-health-and-safety-climate-survey-tool-within-a-mining-setting
#8
Anthony W Parker, Megan J Tones, Gabrielle E Ritchie
INTRODUCTION: This study aimed to design, implement and evaluate the reliability and validity of a multifactorial and multilevel health and safety climate survey (HSCS) tool with utility in the Australian mining setting. METHODS: An 84-item questionnaire was developed and pilot tested on a sample of 302 Australian miners across two open cut sites. RESULTS: A 67-item, 10 factor solution was obtained via exploratory factor analysis (EFA) representing prioritization and attitudes to health and safety across multiple domains and organizational levels...
September 2017: Journal of Safety Research
https://www.readbyqxmd.com/read/28879322/difficult-airway-management-in-a-patient-with-a-thin-mandible
#9
Hong-Seok Choi, Jong-Shik Oh, Eun-Jung Kim, Ji-Young Yoon, Ji-Uk Yoon, Cheul-Hong Kim
A 47-year-old woman was referred for surgical treatment of osteomyelitis of the mandible. She had already undergone three previous surgeries. Pre-anesthetic airway evaluation predicted a difficult airway, due to the thin, retro-positioned mandible, tongue, and atrophic changes in the lips and soft tissue. We inserted packing gauzes in the buccal mucosa for easier mask fitting and ventilation. During direct laryngoscopic intubation with a nasotracheal tube (NTT), fracture of a thin mandible can easily occur...
December 2016: J Dent Anesth Pain Med
https://www.readbyqxmd.com/read/28879317/the-evaluation-of-implementing-smart-patient-controlled-analgesic-pump-with-a-different-infusion-rate-for-different-time-duration-on-postoperative-pain-management
#10
Saeyoung Kim, Younghoon Jeon, Hyeonjun Lee, Jung A Lim, Sungsik Park, Si Oh Kim
BACKGROUND: Control of postoperative pain is an important aspect of postoperative patient management. Among the methods of postoperative pain control, patient-controlled analgesia (PCA) has been the most commonly used. This study tested the convenience and safety of a PCA method in which the dose adjusted according to time. METHODS: This study included 100 patients who had previously undergone orthognathic surgery, discectomy, or total hip arthroplasty, and wished to control their postoperative pain through PCA...
December 2016: J Dent Anesth Pain Med
https://www.readbyqxmd.com/read/28878195/1-945-25-dihydroxyvitamin-d3-attenuates-tgf-946-induced-pro-fibrotic-effects-in-human-lung-epithelial-cells-through-inhibition-of-epithelial-mesenchymal-transition
#11
Fei Jiang, Yong Yang, Lian Xue, Bingyan Li, Zengli Zhang
Pulmonary fibrosis is a progressive fibrotic lung disease of persisting lung injury and ineffective wound repair, with poor prognosis. Epithelial-mesenchymal transition (EMT) of alveolar epithelia cells is an early event in the development of pulmonary fibrosis, and transforming growth factor β (TGF-β) is an acknowledged inducer of EMT. Epidemiological studies demonstrated that serum levels of 25-hydroxy-vitamin D were associated with the presence of fibrosis diseases. We investigated whether vitamin D attenuated TGF-β-induced pro-fibrotic effects through inhibiting EMT in human alveolar epithelia A549 cells...
September 6, 2017: Nutrients
https://www.readbyqxmd.com/read/28876961/vitamin-d-replacement-improves-tear-osmolarity-in-patients-with-vitamin-d-deficiency
#12
Muhammed Kizilgul, Seyfullah Kan, Ozgur Ozcelik, Selvihan Beysel, Mahmut Apaydin, Bekir Ucan, Erman Cakal
BACKGROUND: Vitamin D deficiency is a common health problem worldwide. Many parts of the human eye, including the epithelium of the cornea, lens, ciliary body, and retinal pigment epithelium, as well as the corneal endothelium, ganglion cell layer, and retinal photoreceptors, contain vitamin D receptor (VDR). Dry eye is also a common health problem. An adequate tear film is required for maintaining health and function of the eye. Tear hyperosmolarity is considered to be the cause of ocular surface inflammation, symptoms, and tissue damage...
September 6, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28875057/citation-analysis-for-biomedical-and-health-sciences-journals-published-in-korea
#13
Juyeon Oh, Hyejung Chang, Jung A Kim, Mona Choi, Ziyoung Park, Yoonhee Cho, Eun-Gyu Lee
OBJECTIVES: A citation analysis of biomedical and health sciences journals was conducted based on their enlistment in journal databases to identify the factors contributing to the citation metrics. METHODS: Among the 1,219 academic journals managed by the National Center for Medical Information and Knowledge at the Korea Centers for Disease Control and Prevention, 556 journals were included for analysis as of July 2016. The characteristics of the journals include history years, publication media, language, open-access policy as well as the status enlisted in international and domestic databases, such as Science Citation Index (SCI), Scopus, Medline, PubMed Central, Embase, and Korea Citation Index (KCI)...
July 2017: Healthcare Informatics Research
https://www.readbyqxmd.com/read/28871118/durable-and-self-hydrating-tungsten-carbide-based-composite-polymer-electrolyte-membrane-fuel-cells
#14
Weiqing Zheng, Liang Wang, Fei Deng, Stephen A Giles, Ajay K Prasad, Suresh G Advani, Yushan Yan, Dionisios G Vlachos
Proton conductivity of the polymer electrolyte membranes in fuel cells dictates their performance and requires sufficient water management. Here, we report a simple, scalable method to produce well-dispersed transition metal carbide nanoparticles. We demonstrate that these, when added as an additive to the proton exchange Nafion membrane, provide significant enhancement in power density and durability over 100 hours, surpassing both the baseline Nafion and platinum-containing recast Nafion membranes. Focused ion beam/scanning electron microscope tomography reveals the key membrane degradation mechanism...
September 4, 2017: Nature Communications
https://www.readbyqxmd.com/read/28857853/valproic-acid-combined-with-postcardiac-arrest-hypothermic-targeted-temperature-management-prevents-delayed-seizures-and-improves-survival-in-a-rat-cardiac-arrest-model
#15
Joo Suk Oh, Jinka Tulasi, Ren Xiaodan, William C Stacey, Robert W Neumar
OBJECTIVES: High-dose valproic acid in combination with hypothermic-targeted temperature management has been reported to synergistically improve neurologic outcomes after cardiac arrest. This study investigated the potential synergistic mechanisms. DESIGN: Prospective, randomized, experimental study. SETTING: University research institution. SUBJECTS: Male Long Evans rats. INTERVENTION: Rats resuscitated from asphyxial cardiac arrest were randomized to one of the three groups: normothermic-targeted temperature management (37°C ± 1°C), hypothermic-targeted temperature management (33° ± 1° × 24 hr + placebo infusion), hypothermic-targeted temperature management plus high-dose valproic acid (300 mg/kg IV × 1 initiated 5 min post return of spontaneous circulation and infused over 20 min) (hypothermic-targeted temperature management + valproic acid)...
August 28, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28857178/12-oh-17-18-epoxyeicosatetraenoic-acid-alleviates-eosinophilic-airway-inflammation-in-murine-lungs
#16
Takao Mochimaru, Koichi Fukunaga, Jun Miyata, Masako Matsusaka, Katsunori Masaki, Hiroki Kabata, Soichiro Ueda, Yusuke Suzuki, Tomomi Goto, Daisuke Urabe, Masayuki Inoue, Yosuke Isobe, Makoto Arita, Tomoko Betsuyaku
BACKGROUND: Asthma is characterized by airway inflammation and obstruction with eosinophil infiltration into the airway. Arachidonic acid, an omega-6 fatty acid, is metabolized into cysteinyl leukotriene with pro-inflammatory properties for allergic inflammation, whereas the omega-3 fatty acid eicosapentaenoic acid (EPA) and its downstream metabolites are known to have anti-inflammatory effects. In this study, we investigated the mechanism underlying the counter-regulatory roles of EPA in inflamed lungs...
August 30, 2017: Allergy
https://www.readbyqxmd.com/read/28854957/a-systematic-synthesis-of-direct-costs-to-treat-and-manage-tuberculosis-disease-applied-to-california-2015
#17
Peter Oh, Lisa Pascopella, Pennan M Barry, Jennifer M Flood
BACKGROUND: The cost of treating and managing cases of active tuberculosis (TB) disease-from diagnosis to treatment completion-is needed by agencies working on public health budgets, resource allocation and cost-effectiveness analysis. Although components of TB costs have been published in the United States (US), no recent study has assessed overall costs for TB care and potential gaps. To systematically review the US literature for costs of treating and managing cases of active TB disease, adjust these costs to current (2015) values, and assess gaps...
August 30, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28846561/incidence-and-management-of-fractured-dental-implants-case-reports
#18
Soo-Young Jin, Su-Gwan Kim, Ji-Su Oh, Jae-Seek You, Mi-Ae Jeong
The fracture of dental implants is a rare occurrence in clinical settings. Possible causes of implant fracture include design or production flaws, overloaded occlusion force, implant location, metal fatigue, and bone resorption around the implant. This study reports on the successful removal and reimplantation of fractured implants.
August 25, 2017: Implant Dentistry
https://www.readbyqxmd.com/read/28842760/prevalence-of-vitamin-d-deficiency-in-chronic-and-subacute-low-back-pain-patients-in-india-a-triple-arm-controlled-study
#19
Ajay Panwar, Chandrasekhar Valupadas, Madhavarao Veeramalla, Hunsur N Vishwas
Vitamin D is vital for musculoskeletal health and may be associated with subacute and chronic low back pain. The objective of this study was to estimate the prevalence of vitamin D deficiency among chronic low back pain (CLBP) and subacute low back pain (SLBP), and compare the same with healthy controls. This study was designed as triple-arm case-control study comprising of CLBP, SLBP, and controls. SLBP and CLBP cases were consecutively enrolled over 3 months of winter season from November 2016 to January 2017...
August 25, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28831946/long-term-recovery-from-hurricane-sandy-evidence-from-a-survey-in-new-york-city
#20
Elisaveta P Petkova, Jaishree Beedasy, Eun Jeong Oh, Jonathan J Sury, Erin M Sehnert, Wei-Yann Tsai, Michael J Reilly
OBJECTIVES: This study aimed to examine a range of factors influencing the long-term recovery of New York City residents affected by Hurricane Sandy. METHODS: In a series of logistic regressions, we analyzed data from a survey of New York City residents to assess self-reported recovery status from Hurricane Sandy. RESULTS: General health, displacement from home, and household income had substantial influences on recovery. Individuals with excellent or fair health were more likely to have recovered than were individuals with poor health...
August 23, 2017: Disaster Medicine and Public Health Preparedness
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