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https://www.readbyqxmd.com/read/27912750/fermented-barley-and-soybean-bs-mixture-enhances-intestinal-barrier-function-in-dextran-sulfate-sodium-dss-induced-colitis-mouse-model
#1
Jong Kyu Woo, Seungho Choi, Ju-Hee Kang, Dae Eung Kim, Byung-Serk Hurh, Jong-Eun Jeon, Sun Yeou Kim, Seung Hyun Oh
BACKGROUND: Inflammatory bowel disease (IBD) is characterized by chronic or relapsing immune system activation and inflammation within the gastrointestinal tract. The lack of safety and efficacy of standard therapies, the use of food supplements for managing IBD is increasing, and many studies have reported that various food supplements provide many beneficial effects for the IBD. METHODS: This study aimed to evaluate the anti-colitis effects of dietary supplementation with a fermented barley and soybean mixture (BS) on intestinal inflammation using a murine model of IBD...
December 3, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27909678/bridge-tenodesis-a-secure-fixation-technique-for-biceps-long-head-tendinopathy-during-arthroscopic-rotator-cuff-repair-using-a-suture-bridge-technique
#2
Jin-Young Park, Jae-Hyung Lee, Kyung-Soo Oh, Seok-Won Chung, Jin-Young Bang, Young-Min Noh
Tendinopathy of the long head of the biceps is often found as an intra-articular pathology in the glenohumeral joint. Because long head of the biceps lesions are common, surgical intervention to properly manage the long head of the biceps has become an important issue. Both tenodesis and tenotomy have been shown to provide benefits in biceps long head tendinopathy. But because of concerns about muscle power reduction, cramping, and "Popeye's deformity," which may result from biceps tenotomy, biceps tenodesis is a good option for treating biceps lesions...
October 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/27906089/esophageal-perforation-after-perioperative-transesophageal-echocardiography-a-case-report
#3
Hyun-Chang Kim, Jung-Hyou Oh, Yong-Cheol Lee
BACKGROUND: Transesophageal echocardiography is widely used in cardiac surgery. Transesophageal echocardiography probe insertion and manipulation can injure the esophagus. CASE PRESENTATION: A 76-year-old Asian man was admitted to our hospital for coronary artery bypass graft revascularization surgery. A right carotid endarterectomy was successfully performed 2 days before coronary artery bypass graft revascularization surgery. After the coronary artery bypass graft revascularization surgery was done successfully, postoperative computed tomography and esophagography revealed perforation of the middle esophagus...
December 1, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27904464/effectiveness-of-different-classes-of-fungicides-on-botrytis-cinerea-causing-gray-mold-on-fruit-and-vegetables
#4
Joon-Oh Kim, Jong-Hwan Shin, Adiyantara Gumilang, Keun Chung, Ki Young Choi, Kyoung Su Kim
Botrytis cinerea is a necrotrophic pathogen causing a major problem in the export and post-harvest of strawberries. Inappropriate use of fungicides leads to resistance among fungal pathogens. Therefore, it is necessary to evaluate the sensitivity of B. cinerea to various classes of fungicide and to determine the effectiveness of different concentrations of commonly used fungicides. We thus evaluated the effectiveness of six classes of fungicide in inhibiting the growth and development of this pathogen, namely, fludioxonil, iprodione, pyrimethanil, tebuconazole, fenpyrazamine, and boscalid...
December 2016: Plant Pathology Journal
https://www.readbyqxmd.com/read/27903197/upfront-boost-gamma-knife-leading-edge-radiosurgery-to-flair-mri-defined-tumor-migration-pathways-in-174-patients-with-glioblastoma-multiforme-a-15-year-assessment-of-a-novel-therapy
#5
Christopher M Duma, Brian S Kim, Peter V Chen, Marianne E Plunkett, Ralph Mackintosh, Marlon S Mathews, Ryan M Casserly, Gustavo A Mendez, Daniel J Furman, Garrett Smith, Nathan Oh, Chad A Caraway, Ami R Sanathara, Robert O Dillman, Azzurra-Sky Riley, David Weiland, Lian Stemler, Ruslana Cannell, Daniela Alexandru Abrams, Alexa Smith, Christopher M Owen, Burton Eisenberg, Michael Brant-Zawadzki
OBJECTIVE Glioblastoma multiforme (GBM) is composed of cells that migrate through the brain along predictable white matter pathways. Targeting white matter pathways adjacent to, and leading away from, the original contrast-enhancing tumor site (termed leading-edge radiosurgery [LERS]) with single-fraction stereotactic radiosurgery as a boost to standard therapy could limit the spread of glioma cells and improve clinical outcomes. METHODS Between December 2000 and May 2016, after an initial diagnosis of GBM and prior to or during standard radiation therapy and carmustine or temozolomide chemotherapy, 174 patients treated with radiosurgery to the leading edge (LE) of tumor cell migration were reviewed...
December 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27901304/predicting-occurrence-of-juvenile-shark-habitat-to-improve-conservation-planning
#6
Beverly Z L Oh, Ana M M Sequeira, Mark G Meekan, Jonathan L W Ruppert, Jessica J Meeuwig
Fishing and habitat degradation have increased the extinction risk of sharks, and conservation strategies recognize that survival of juveniles is critical for the effective management of shark populations. Despite the rapid expansion of marine protected areas (MPAs) globally, the paucity of shark-monitoring data on large scales (100s-1000s km) means that the effectiveness of MPAs in halting shark declines remains unclear. Using data collected by baited remote underwater video systems (BRUVS) in northwestern Australia, we developed generalized linear models to elucidate the ecological drivers of the occurrence of juvenile shark habitat...
November 30, 2016: Conservation Biology: the Journal of the Society for Conservation Biology
https://www.readbyqxmd.com/read/27896829/immunomodulatory-and-immunosuppressive-roles-of-1%C3%AE-25-oh-2d3-in-autoimmune-diseases
#7
REVIEW
Hussaini Alhassan Mohammed, Ali Akbar Saboor-Yaraghi, Abbas Mirshafiey, Haumayon Vahedi, Mohammad Reza Shiri-Shahsavar, Ateke Mousavi Nasl Khameneh
BACKGROUND: Autoimmune diseases are pathological conditions characterized by abnormal. responses, accompanied by auto-antibodies to self-molecules. The roles vitamin D in autoimmune diseases has increased significantly in the recent past from its functions in calcium and phosphate homeostasis, it is now involved in the regulations and proliferations of Th1 and Th17 lymphocyte. 1α,25(OH)2D3 in very important in ameliorations of inflammatory disorders arising from autoimmune diseases, but the mechanism by which this is done is still a bone of contentions...
November 29, 2016: Scandinavian Journal of Immunology
https://www.readbyqxmd.com/read/27896190/the-use-of-locally-applied-vibration-to-minimize-pain-during-fractional-co2-laser-therapy-in-living-liver-donor-scar-management
#8
Sinyoung Song, Dong Hoon Choi, Tae Suk Oh
BACKGROUND: Fractional CO2 laser is an effective treatment for scars, but most patients complain about sharp burning pain, even after the application of lidocaine ointment. This study analyzed the impact of a vibrating device to nonpharmacologically reduce the acute pain of laser treatment, in accordance with the gate control theory of pain management. METHODS: This is a prospective study performed from May 2013 through March 2014. Fifty-three patients (mean age, 26...
November 2016: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/27896179/clinical-factors-associated-with-the-non-operative-airway-management-of-patients-with-robin-sequence
#9
Frank P Albino, Benjamin C Wood, Kevin D Han, Sojung Yi, Mitchel Seruya, Gary F Rogers, Albert K Oh
BACKGROUND: The indications for surgical airway management in patients with Robin sequence (RS) and severe airway obstruction have not been well defined. While certain patients with RS clearly require surgical airway intervention and other patients just as clearly can be managed with conservative measures alone, a significant proportion of patients with RS present with a more confusing and ambiguous clinical course. The purpose of this study was to describe the clinical features and objective findings of patients with RS whose airways were successfully managed without surgical intervention...
November 2016: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/27893663/revision-surgery-for-curve-progression-after-implant-removal-following-posterior-fusion-only-at-a-young-age-in-the-treatment-of-congenital-scoliosis-a-case-report
#10
Dong-Gune Chang, Jae Hyuk Yang, Jung-Hee Lee, Jung-Sub Lee, Seung-Woo Suh, Jin-Hyok Kim, Seung-Yeol Oh, Woojin Cho, Jong-Beom Park, Se-Il Suk
RATIONALE: Congenital scoliosis due to a hemivertebra creates a wedge-shaped deformity, which progresses and causes severe spinal deformities as an individual grows. The treatment of congenital scoliosis focuses on early diagnosis and appropriate surgical management before the development of severe deformity. PATIENT CONCERNS: We report the case of a 4-year-old male child with a left thoracolumbar scoliosis of 27° (T10-T12) due to a T11 hemivertebra who was treated by posterior fusion and pedicle screw fixation at the age of 4 years...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27888438/transanal-hemorrhoidal-dearterialization-with-mucopexy-versus-open-hemorrhoidectomy-in-the-treatment-of-hemorrhoids-a-meta-analysis-of-randomized-control-trials
#11
L Xu, H Chen, G Lin, Q Ge, H Qi, X He
BACKGROUND: The aim of this study was to analyse the outcomes of transanal hemorrhoidal dearterialization with mucopexy (THDm) versus open hemorrhoidectomy (OH) in the management of hemorrhoids. METHODS: Randomized controlled trials in English were found by searching PubMed, Web of science, EMBASE, and the Cochrane Library database. Trials that compared THDm with OH were identified. Data were extracted independently for each study, and a meta-analysis was performed using fixed and random effects models...
November 25, 2016: Techniques in Coloproctology
https://www.readbyqxmd.com/read/27886576/the-effect-of-early-goal-directed-therapy-for-treatment-of-severe-sepsis-or-septic-shock-a-systemic-review-and-meta-analysis
#12
Sun-Kyung Park, Su Rin Shin, Min Hur, Won Ho Kim, Eun-Ah Oh, Soo Hee Lee
PURPOSE: To assess the effects of early goal-directed therapy (EGDT) on reducing mortality compared with conventional management of severe sepsis or septic shock. MATERIALS AND METHODS: We included a systemic review, using the Medline and EMBASE. Seventeen randomized trials with 5765 patients comparing EGDT with usual care were included. RESULTS: There were no significant differences in mortality between EGDT and control groups (relative risk [RR], 0...
October 30, 2016: Journal of Critical Care
https://www.readbyqxmd.com/read/27884644/evaluating-augmentation-with-calcium-phosphate-cement-chronos-inject-for-bone-defects-after-internal-fixation-of-proximal-tibial-fractures-a-prospective-multi-center-observational-study
#13
Ki Chul Park, Chang-Wug Oh, Young-Hoon Jo
INTRODUCTION: Managing subchondral bone defects in proximal tibia fractures after plateau reduction is an important consideration.ChronOSInjectis a recently developed calcium phosphate bone substitute that shows relatively fast osteointegration. HYPOTHESIS: UsingchronOS Inject during internal fixation of proximal tibial fractures provides a satisfactory treatment option that is both clinically and radiologically safe. MATERIALS AND METHODS: Patients enrolled in this study were treated with ChronOS Injectbone void filler, during internal fixation of proximal tibial fractures...
November 21, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/27882481/assessment-criteria-for-vitamin-d-deficiency-insufficiency-in-japan-proposal-by-an-expert-panel-supported-by-the-research-program-of-intractable-diseases-ministry-of-health-labour-and-welfare-japan-the-japanese-society-for-bone-and-mineral-research-and-the
#14
Ryo Okazaki, Keiichi Ozono, Seiji Fukumoto, Daisuke Inoue, Mika Yamauchi, Masanori Minagawa, Toshimi Michigami, Yasuhiro Takeuchi, Toshio Matsumoto, Toshitsugu Sugimoto
Vitamin D is indispensable for the maintenance of bone and mineral health. Inadequate vitamin D action increases the risk for various musculoskeletal/mineral events including fracture, fall, secondary hyperparathyroidism, diminished response to antiresorptives, rickets/osteomalacia, and hypocalcemia. Its most common cause in recent years is vitamin D deficiency/insufficiency, clinically defined by a low serum 25-hydroxyvitamin D [25(OH)D] level. Guidelines for vitamin D insufficiency/deficiency defined by serum 25(OH)D concentrations have been published all over the world...
November 23, 2016: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/27882418/compliance-with-guidelines-of-enhanced-recovery-after-surgery-in-elderly-patients-undergoing-gastrectomy
#15
Oh Jeong, Young Kyu Park, Mi Ran Jung, Seong Yeob Ryu
BACKGROUND: Enhanced recovery after surgery (ERAS) aims at expediting postoperative recovery by implementing specific strategies in perioperative management. However, the tolerance to such fast-tracking protocols is under debate, especially in elderly patients. We aimed to investigate rate of compliance with the main ERAS guidelines in elderly gastrectomy patients. METHODS: Using data for 168 gastric cancer patients who underwent ERAS after gastrectomy as part of Clinical Trial NCT01653496, we calculated the rates of compliance with nine main ERAS guidelines and compared the compliance rates of elderly (≥70 years) and non-elderly (<70 years) patients...
November 23, 2016: World Journal of Surgery
https://www.readbyqxmd.com/read/27879568/effect-of-immunotherapy-status-on-outcomes-in-patients-with-metastatic-melanoma-to-the-spine
#16
Ganesh M Shankar, Bryan D Choi, Benjamin L Grannan, Kevin Oh, John H Shin
STUDY DESIGN: Retrospective cohort study OBJECTIVE.: We performed a retrospective study of patients treated at our institution over the last 3 years to assess predictive value of immunotherapy exposure on overall survival of patients with metastatic melanoma to the spine in an effort to better inform surgical decision making. SUMMARY OF BACKGROUND DATA: Modern management of metastatic melanoma includes adjuvant targeted therapies and immunomodulators that have shown to significantly improve overall survival...
November 22, 2016: Spine
https://www.readbyqxmd.com/read/27869547/dynamic-risk-stratification-for-predicting-recurrence-in-patients-with-differentiated-thyroid-cancer-treated-without-radioactive-iodine-remnant-ablation-therapy
#17
Suyeon Park, Won Gu Kim, Eyun Song, Hye-Seon Oh, Mijin Kim, Hyemi Kwon, MinJi Jeon, Tae Yong Kim, YoungKee Shong, Won Bae Kim
BACKGROUND: Increased incidence of small differentiated thyroid cancer (DTC) has emphasized the need for risk stratification and individualized disease management for these low risk DTCs. The aim was to validate a new dynamic risk stratification (DRS) system for prediction of structural recurrent/persistent disease in patients with DTC treated without radioactive iodine (RAI) remnant ablation therapy. METHODS: This historical cohort study included 357 patients with DTC treated with lobectomy or total thyroidectomy without RAI therapy...
November 21, 2016: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/27867307/adequate-vitamin-d-intake-but-low-serum-levels-in-pediatric-asthma-patients-a-pilot-study-alberta-children-s-hospital
#18
Sarah Howe McKenna, Tanis R Fenton, Mary Noseworthy, Mark Anselmo
Background. We assessed vitamin D intakes and serum 25(OH) vitamin D levels in pediatric asthma patients on moderate-to-high dose inhaled steroids and compared them to published findings of healthy children in our city. Methods. Parents and/or patients were interviewed to estimate the children's vitamin D intakes from foods and supplements (using an adapted validated food frequency questionnaire) and asthma duration and management. Vitamin D status: serum 25-hyroxy vitamin D (25(OH)D) was obtained from the medical records...
2016: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
https://www.readbyqxmd.com/read/27867203/epac2a-null-mice-exhibit-obesity-prone-nature-more-susceptible-to-leptin-resistance
#19
M Hwang, Y Go, J-H Park, S-K Shin, S E Song, B-C Oh, S-S Im, I Hwang, Y H Jeon, I-K Lee, S Seino, D-K Song
BACKGROUND: The exchange protein directly activated by cAMP (Epac), which is primarily involved in cAMP signaling, has been known to be essential for controlling body energy metabolism. Epac has two isoforms: Epac1 and Epac2. The function of Epac1 on obesity was unveiled using Epac1 knockout (KO) mice. However, the role of Epac2 in obesity remains unclear. METHODS: To evaluate the role of Epac2 in obesity, we used Epac2a KO mice, which is dominantly expressed in neurons and endocrine tissues...
November 21, 2016: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/27865374/clinical-implications-of-the-extent-of-braf-v600e-alleles-in-patients-with-papillary-thyroid-carcinoma
#20
Lihua Liu, Jae Won Chang, Seung-Nam Jung, Hee Sung Park, Taejeong Oh, Young Chang Lim, Bon Seok Koo
OBJECTIVE: There are many conflicting reports about the clinical implications of BRAF(V600E) in papillary thyroid cancer (PTC). We investigated the associations between the extent of BRAF(V600E) alleles and both clinico-pathological features and recurrence of PTC. MATERIALS AND METHODS: Carcinoma tissues from 60 patients with PTC were genotyped for BRAF(V600E) using pyrosequencing, and the clinico-pathological factors and disease outcomes of the patients were examined...
November 2016: Oral Oncology
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