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https://www.readbyqxmd.com/read/28431123/surgical-intervention-for-ground-glass-dominant-lesions-observation-or-outright-resection
#1
Mariko Fukui, Kenji Suzuki, Takeshi Matsunaga, Shiaki Oh, Kazuya Takamochi
Background: The management of ground glass opacity (GGO) on computed tomography (CT) remains controversial. Information of the relationship between clinical behavior and pathological invasiveness of GGO is valuable for management. We conducted this retrospective study to establish differences in the pathological invasiveness between GGO with and without changes. Methods: Among 1762 patients, the following criteria was used: (1) maximum tumor diameter of 3 cm or less, (2) tumor having 50% or more GGO and (3) resection after at least three months of follow up...
April 18, 2017: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28419333/surgical-resection-for-clinical-stage-i-radiological-pure-solid-lung-cancer-that-met-the-current-high-risk-criteria
#2
Aritoshi Hattori, Takeshi Matsunaga, Kazuya Takamochi, Shiaki Oh, Kenji Suzuki
Objective: We assessed whether surgical resection is acceptable for radiological invasive non-small cell lung cancer (NSCLC) that met the current high-risk criteria. Methods: We reviewed 500 clinical-Stage I NSCLCs with a radiological pure-solid appearance. High-risk criterion was defined as follows: (1) preoperative FEV1% ≤ 50% or DLco% ≤ 50%, (2) age > 75y with 50% < FEV1% < 60% or 50% < DLco% < 60%, and (3) three or more severe general comorbidities...
April 13, 2017: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28410638/utility-of-objective-chest-tube-management-after-pulmonary-resection-using-a-digital-drainage-system
#3
Kazuya Takamochi, Kota Imashimizu, Mariko Fukui, Tatsuo Maeyashiki, Mikiko Suzuki, Takuya Ueda, Hironori Matsuzawa, Shunki Hirayama, Takeshi Matsunaga, Shiaki Oh, Kenji Suzuki
BACKGROUND: We sought to evaluate the clinical utility of chest tube management after pulmonary resection based on objective digital monitoring of pleural pressure and digital surveillance for air leaks. METHODS: We prospectively recorded the perioperative data of 308 patients who underwent pulmonary resection between December 2013 and January 2016. We used information from a digital monitoring thoracic drainage system to measure peak air leakage during the first 24 hours after the operation, patterns of air leakage over the first 72 hours, and patterns of pleural pressure changes until the chest tubes were removed...
April 12, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28409698/less-is-more-does-the-addition-of-barrel-staves-improve-results-in-endoscopic-strip-craniectomy-for-sagittal-craniosynostosis
#4
Benjamin C Wood, Edward S Ahn, Joanna Y Wang, Albert K Oh, Robert F Keating, Gary F Rogers, Suresh N Magge
OBJECTIVE Endoscopic strip craniectomy (ESC) with postoperative helmet orthosis is a well-established treatment option for sagittal craniosynostosis. There are many technical variations to the surgery ranging from simple strip craniectomy to methods that employ multiple cranial osteotomies. The purpose of this study was to determine whether the addition of lateral barrel-stave osteotomies during ESC improved morphological outcomes. METHODS An IRB-approved retrospective review was conducted on a consecutive series of cases involving ESC for sagittal craniosynostosis at 2 different institutions from March 2008 to August 2014...
April 14, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28400147/quality-of-life-and-mediating-role-of-patient-scar-assessment-in-burn-patients
#5
Hyunjin Oh, Sunjoo Boo
INTRODUCTION: In this study, we examined the plausibility of the mediating effect of the levels of patient scar assessment on the relationship between burn severity measured with total body surface area and burn-specific health-related quality of life (HRQL) among patients with burns in South Korea. METHODS: In this cross sectional descriptive study, we collected data from 100 burn patients in three burn centers specializing in burn care in South Korea. Patient scar assessment, burn specific HRQL, and burn-related characteristics were self-reported with anonymous, paper-based surveys...
April 8, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28399609/early-adverse-events-and-long-term-outcomes-of-endoscopic-sphincterotomy-in-a-pediatric-population-a-single-center-experience
#6
Jin Min Cho, In Sook Jeong, Hyun Jin Kim, Seak Hee Oh, Kyung Mo Kim
Background and aims: The use of endoscopic sphincterotomy (EST) in the management of pancreaticobiliary disease in children is increasing. However, studies of long-term outcomes are limited in pediatric patients. Therefore, this study evaluated the early adverse events and long-term outcomes following EST in pediatric patients. Patients and methods: We retrospectively analyzed data from 198 pediatric patients who underwent ESTs at Asan Medical Center Children's Hospital between 1994 and 2013. The median age was 8...
April 11, 2017: Endoscopy
https://www.readbyqxmd.com/read/28398925/urgent-chemotherapy-for-life-threatening-complications-related-to-solid-neoplasms
#7
Yoann Zerbib, Antoine Rabbat, Muriel Fartoukh, Naïke Bigé, Claire Andréjak, Julien Mayaux, Nicolas De Prost, Benoît Misset, Virginie Lemiale, Fabrice Bruneel, Julien Maizel, Sylvie Ricome, Frédéric Jacobs, Caroline Bornstain, Hervé Dupont, François Baudin, Elie Azoulay, Frédéric Pène
OBJECTIVES: Solid neoplasms can be directly responsible for organ failures at the time of diagnosis or relapse. The management of such specific complications relies on urgent chemotherapy and eventual instrumental or surgical procedures, combined with advanced life support. We conducted a multicenter study to address the prognosis of this condition. DESIGN: A multicenter retrospective (2001-2015) chart review. SETTING: Medical and respiratory ICUs...
April 10, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28395501/multidisciplinary-team-approach-for-the-management-of-patients-with-locally-advanced-non-small-cell-lung-cancer-searching-the-evidence-to-guide-the-decision
#8
REVIEW
In-Jae Oh, Sung-Ja Ahn
Locally advanced non-small cell lung cancer (LA-NSCLC) is composed of heterogeneous subgroups that require a multidisciplinary team approach in order to ensure optimal therapy for each patient. Since 2010, the National Comprehensive Cancer Network has recommended chemoradiation therapy (CRT) for bulky mediastinal disease and surgical combination for those patients with single-station N2 involvement who respond to neoadjuvant therapy. According to lung cancer tumor boards, thoracic surgeons make a decision on the resectability of the tumor, if it is determined to be unresectable, concurrent CRT (CCRT) is considered the next choice...
March 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/28385008/use-of-stem-cell-sheets-expressing-bone-morphogenetic-protein-7-in-the-management-of-a-nonunion-radial-fracture-in-a-toy-poodle
#9
Jaeyong Song, Yongsun Kim, Oh-Kyeong Kweon, Byung-Jae Kang
A 12-year-old castrated Toy Poodle was referred to Kangwon National University Animal Hospital with an oligotrophic nonunion fracture in the left distal 1/3 of the radius and an intact ulna. After fixation using a locking plate and screws, adipose-derived mesenchymal stem cell sheets expressing bone morphogenetic protein 7 (BMP-7) were transplanted to the fracture site to enhance the healing activity. The fracture healed at 9 weeks after surgery. In the present case, the mesenchymal stem cell sheets expressing BMP-7 promoted bone regeneration and healing in a nonunion fracture...
April 6, 2017: Journal of Veterinary Science
https://www.readbyqxmd.com/read/28380559/management-options-for-contaminated-urban-soils-to-reduce-public-exposure-and-maintain-soil-health
#10
John F Obrycki, Nicholas T Basta, Steven W Culman
Soil management in urban areas faces dual challenges of reducing public exposure to soil contaminants, such as lead (Pb) and polycyclic aromatic hydrocarbons, and maintaining soil function. This study evaluated three management options for an urban lot in Cleveland, OH, containing 185 to 5197 mg Pb kg and 0.28 to 5.50 mg benzo(a)pyrene kg. Treatment options included: (i) cap the site with a soil blend containing compost and beneficially reused dredged sediments, (ii) mix compost with the soil, and (iii) mix compost and sediments with the soil...
March 2017: Journal of Environmental Quality
https://www.readbyqxmd.com/read/28372517/concentrations-of-calcium-and-25-hydroxycholecalciferol-vitamin-d3-in-plasma-of-wild-k%C3%A4-k%C3%A4-p%C3%A5-strigops-habroptilus-living-on-two-islands-in-new-zealand
#11
J Chatterton, A Pas, S Alexander, M Leech, R Jakob-Hoff, B P Jensen, A Digby
AIMS: This initial study had the objectives of describing the concentrations of ionised calcium and 25-hydroxycholecalciferol (25(OH)D3) in the blood of wild kākāpō (Strigops habroptilus) living on two islands in New Zealand, and to determine the effects of supplementary feeding on these blood parameters. METHODS: Blood samples were obtained from 33 kākāpō living on two offshore islands during routine health checks in 2015. Birds on Hauturu were sampled in May (n=5) and birds on Whenua Hou were sampled in July (n=15) and November (n=26)...
April 3, 2017: New Zealand Veterinary Journal
https://www.readbyqxmd.com/read/28372500/clinical-significance-of-bioimpedance-spectroscopy-in-critically-ill-patients
#12
Shang-Feng Yang, Ching-Min Tseng, I-Fan Liu, Shin-Hung Tsai, Wein-Shung Kuo, Tien-Ping Tsao
BACKGROUND: Early fluid resuscitation is a key aspect in the successful management of critically ill patients, but the optimal goal for volume control after the acute stage of critical illness remains unclear. This study aimed to evaluate the prognostic value of bioimpedance spectrometry for fluid management in critically ill patients. METHODS: In this prospective observational study, patients who consented to participate were screened within the first 24 hours of admission to a medical intensive care unit (ICU) from February 4, 2015, to January 31, 2016...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/28371733/human-exposure-to-pcdds-and-their-precursors-from-heron-and-tern-eggs-in-the-yangtze-river-delta-indicate-pcp-origin
#13
Yihui Zhou, Ge Yin, Lillemor Asplund, Kathryn Stewart, Panu Rantakokko, Anders Bignert, Päivi Ruokojärvi, Hannu Kiviranta, Yanling Qiu, Zhijun Ma, Åke Bergman
Polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) are highly toxic to humans and wildlife. In the present study, PCDD/Fs were analyzed in the eggs of whiskered terns (Chlidonias hybrida), and genetically identified eggs from black-crowned night herons (Nycticorax nycticorax) sampled from two lakes in the Yangtze River Delta area, China. The median toxic equivalent (TEQ) of PCDD/Fs were 280 (range: 95-1500) and 400 (range: 220-1100) pg TEQ g(-1) lw (WHO, 1998 for birds) in the eggs of black-crowned night heron and whiskered tern, respectively...
March 31, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28371210/the-proceedings-of-the-15th-professional-conference-on-williams-syndrome
#14
Jennifer R Walton, Marilee A Martens, Barbara R Pober
Williams Syndrome (WS) is a contiguous gene deletion disorder, caused by the deletion of approximately 26-28 genes from chromosome 7 (7q11.23). Individuals with WS have complex medical, developmental, and behavioral features, requiring multidisciplinary and interdisciplinary collaboration. Guidelines detailing the identification, evaluation, and monitoring of individuals with WS need clarification, especially for primary care providers who are first-line in their management. This report summarizes the proceedings of the 2016 Professional Conference on WS in Columbus, OH...
March 29, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28371125/comparison-of-bleb-morphology-between-trabeculectomy-and-deep-sclerectomy-using-a-clinical-grading-scale-and-anterior-segment-optical-coherence-tomography
#15
Lawrence J Oh, Eugene Wong, Julie Lam, Colin I Clement
IMPORTANCE: This study highlights the role of the filtration bleb for IOP management following Trabeculectomy (TRAB) and deep sclerectomy (DS) in Glaucoma. BACKGROUND: This study serves to analyse the bleb morphology and IOP using the Indiana bleb appearance grading scale (IBAGS) and the anterior-segment optical coherence tomography (AS-OCT) postoperatively and at 3 months. DESIGN: Retrospective study by a single surgeon. PARTICIPANTS: 28 patients with open-angle glaucoma were recruited into the study, 14 in each of the TRAB (fornix) and DS groups...
March 30, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28369350/draft-genome-of-the-sea-cucumber-apostichopus-japonicus-and-genetic-polymorphism-among-color-variants
#16
Jihoon Jo, Jooseong Oh, Hyun-Gwan Lee, Hyun-Hee Hong, Sung-Gwon Lee, Seongmin Cheon, Elizabeth M A Kern, Soyeong Jin, Sung-Jin Cho, Joong-Ki Park, Chungoo Park
The Japanese sea cucumber (Apostichopus japonicus Selenka 1867) is an economically important species as a source of seafood and ingredient in traditional medicine. It is mainly found off the coasts of northeast Asia. Recently, substantial exploitation and widespread biotic diseases in A. japonicus have generated increasing conservation concern. However, the genomic knowledge base and resources available for researchers to use in managing this natural resource and to establish genetically based breeding systems for sea cucumber aquaculture are still in a nascent stage...
January 1, 2017: GigaScience
https://www.readbyqxmd.com/read/28363045/assessment-of-serum-25-hydroxyvitamin-d-concentrations-in-two-collections-of-captive-gorillas-gorilla-gorilla-gorilla
#17
Susan L Bartlett, Tai C Chen, Hayley Murphy, Michael F Holick, Michael Tlusty, Eric Baitchman
Serum 25-hydroxyvitamin D concentrations were assessed in subadult to adult captive lowland gorillas ( Gorilla gorilla gorilla) (n = 26) at two institutions with different husbandry and management practices. Serum 25-hydroxyvitamin D (25[OH]D) concentrations for gorillas managed predominantly indoors was low (14.2 ± 5.9 ng/ml), despite consuming commercial biscuits fortified with vitamin D3. Concentrations of 25(OH)D in gorillas with near daily outdoor access were significantly higher than gorillas managed indoors, although many individuals still had serum values below concentrations recommended for adult humans...
March 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28356136/efficacy-and-safety-of-rapid-intermittent-correction-compared-with-slow-continuous-correction-with-hypertonic-saline-in-patients-with-moderately-severe-or-severe-symptomatic-hyponatremia-study-protocol-for-a-randomized-controlled-trial-salsa-trial
#18
Anna Lee, You Hwan Jo, Kyuseok Kim, Soyeon Ahn, Yun Kyu Oh, Huijai Lee, Jonghwan Shin, Ho Jun Chin, Ki Young Na, Jung Bok Lee, Seon Ha Baek, Sejoong Kim
BACKGROUND: Hyponatremia is the most common electrolyte imbalance encountered in clinical practice, associated with increased mortality and length of hospital stay. However, no high-quality evidence regarding whether hypertonic saline is best administered as a continuous infusion or a bolus injection has been found to date. Therefore, in the current study, we will evaluate the efficacy and safety of rapid intermittent correction compared with slow continuous correction with hypertonic saline in patients with moderately severe or severe symptomatic hyponatremia...
March 29, 2017: Trials
https://www.readbyqxmd.com/read/28342973/effects-of-a-sustained-release-formulation-of-1-25-dihydroxyvitamin-d3-glycosides-for-milk-fever-prevention-on-serum-1-25-dihydroxyvitamin-d3-calcium-and-phosphorus-in-dairy-cows
#19
Heinrich Bachmann, Michael Lanz, Susanne Kehrle, Wolfgang Bittner, Annick Toggenburger, Georg A Mathis, Walter Rambeck
Milk fever (MF) is a metabolic disease in dairy cows around parturition. The clinical lead sign is muscular paresis leading in severe cases to paralysis of the affected animal. Multiparturient animals of high performing dairy breeds are most likely to be affected and have a high probability of recurrence. An acute drop in blood calcium levels causes the disease when the demand for calcium at the onset of lactation exceeds the ability to replete blood calcium levels through mobilization from bone and intestinal uptake...
March 23, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28342413/efficacies-of-biochar-and-biochar-based-amendment-on-vegetable-yield-and-nitrogen-utilization-in-four-consecutive-planting-seasons
#20
Hefang Wang, Hao Zheng, Zhixiang Jiang, Yanhui Dai, Guocheng Liu, Lei Chen, Xianxiang Luo, Minhui Liu, Zhenyu Wang
Biochar has been suggested as a potential tailored technology for mediating soil conditions and improving crop yields. However, the efficacies of biochar and biochar-based amendments (e.g., composted biochar) in agricultural soils under a rotation system remain uncertain. In this study, an arable soil was subjected to peanut shell biochar (PBC) and biochar-based amendment (PAD) combined with or without nitrogen (N) fertilizer to evaluate their effects on vegetable yield, N bioavailability, and their relative contribution to vegetable biomass in four consecutive planting seasons...
March 22, 2017: Science of the Total Environment
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