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https://www.readbyqxmd.com/read/28319994/growth-of-bacterial-phytopathogens-in-animal-manures
#1
Wojciech Sledz, Sabina Zoledowska, Agata Motyka, Leszek Kadziński, Bogdan Banecki
Animal manures are routinely applied to agricultural lands to improve crop yield, but the possibility to spread bacterial phytopathogens through field fertilization has not been considered yet. We monitored 49 cattle, horse, swine, sheep or chicken manure samples collected in 14 Polish voivodeships for the most important plant pathogenic bacteria - Ralstonia solanacearum (Rsol), Xanthomonas campestris pv. campestris (Xcc), Pectobacterium carotovorum subsp. carotovorum (Pcc), Pectobacterium atrosepticum (Pba), Erwinia amylovora (Eam), Clavibacter michiganensis subsp...
2017: Acta Biochimica Polonica
https://www.readbyqxmd.com/read/28319949/the-impact-of-kidney-development-on-the-life-course-a-consensus-document-for-action
#2
(no author information available yet)
Hypertension and chronic kidney disease (CKD) have a significant impact on global morbidity and mortality. The Low Birth Weight and Nephron Number Working Group has prepared a consensus document aimed to address the relatively neglected issue for the developmental programming of hypertension and CKD. It emerged from a workshop held on April 2, 2016, including eminent internationally recognized experts in the field of obstetrics, neonatology, and nephrology. Through multidisciplinary engagement, the goal of the workshop was to highlight the association between fetal and childhood development and an increased risk of adult diseases, focusing on hypertension and CKD, and to suggest possible practical solutions for the future...
March 21, 2017: Nephron
https://www.readbyqxmd.com/read/28319889/the-evolution-of-environmental-metalloproteomics-over-the-last-15-years-through-bibliometric-techniques
#3
Rachel Ann Hauser-Davis, Renato Matos Lopes, Fábio Batista Mota, Josino Costa Moreira
Metalloproteomic studies in environmental scenarios are of significant value in elucidating metal uptake, trafficking, accumulation and metabolism linked to biomolecules in biological systems. The advent of this field occurred in the early 2000s, and it has since become an interesting and growing area of interdisciplinary research, although the number of publications in Environmental Metalloprotemics is still very low compared to other metallomic areas. In this context, the evolution of Environmental Metalloprotemics in the last decades was evaluated herein through the use of bibliometric techniques, identifying variables that may aid researchers in this area to form collaborative networks with established scientists in this regard, such as main authors, published articles, institutions, countries and established collaborations involved in academic research on this subject...
March 15, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28319851/-31-p-dephased-13-c-detected-redor-for-nmr-crystallography-at-natural-isotopic-abundance
#4
Alexander I Greenwood, Mary C Clay, Chad M Rienstra
Typically, the process of NMR-based structure determination relies on accurately measuring a large number of internuclear distances to serve as restraints for simulated annealing calculations. In solids, the rotational-echo double-resonance (REDOR) experiment is a widely used approach to determine heteronuclear dipolar couplings corresponding to distances usually in the range of 1.5-8Å. A challenge in the interpretation of REDOR data is the degeneracy of symmetric subunits in an oligomer or equivalent molecules in a crystal lattice, which produce REDOR trajectories that depend explicitly on two or more distances instead of one...
February 28, 2017: Journal of Magnetic Resonance
https://www.readbyqxmd.com/read/28319793/early-response-of-wheat-antioxidant-system-with-special-reference-to-fusarium-head-blight-stress
#5
Valentina Spanic, Marija Viljevac Vuletic, Ivan Abicic, Tihana Marcek
Fusarium head blight (FHB) is a destructive fungal disease of wheat (Triticum aestivum L.) that causes significant grain yield losses and end-use quality reduction associated with contamination by the mycotoxin deoxynivalenol (DON). Three winter wheat varieties ('Vulkan', 'Kraljica' and 'Golubica') were screened for FHB resistance using artificial inoculation technique under field conditions. The aim of this study was to examine a relationship between FHB resistance and the effectiveness of enzyme antioxidant system of wheat varieties under different sampling times (3, 15, 24, 48, 96, 120 and 336 hai)...
March 14, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28319721/methods-for-specifying-spatial-boundaries-of-cities-in-the-world-the-impacts-of-delineation-methods-on-city-sustainability-indices
#6
Yuta Uchiyama, Koichiro Mori
The purpose of this paper is to analyze how different definitions and methods for delineating the spatial boundaries of cities have an impact on the values of city sustainability indicators. It is necessary to distinguish the inside of cities from the outside when calculating the values of sustainability indicators that assess the impacts of human activities within cities on areas beyond their boundaries. For this purpose, spatial boundaries of cities should be practically detected on the basis of a relevant definition of a city...
March 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28319716/multiple-stressors-in-sediments-impact-adjacent-hard-substrate-habitats-and-across-biological-domains
#7
Jasmin C Lawes, Katherine A Dafforn, Graeme F Clark, Mark V Brown, Emma L Johnston
Coastal systems are increasingly impacted by human activities. While the direct effects of individual contaminants have been investigated, the potential for multiple contaminants to impact adjacent hard substrate habitats is poorly understood. Sediment-bound contaminants pose a risk to water column organisms through resuspension and the fluxing of dissolved nutrients and metals. This study experimentally manipulated contaminated coastal sediments in mesocosms with additions of a common fertiliser to investigate the impact on both bacterial biofilms and macrofouling communities on nearby hard substrates...
March 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28319710/glacial-lake-inventory-and-lake-outburst-potential-in-uzbekistan
#8
Maxim A Petrov, Timur Y Sabitov, Irina G Tomashevskaya, Gleb E Glazirin, Sergey S Chernomorets, Elena A Savernyuk, Olga V Tutubalina, Dmitriy A Petrakov, Leonid S Sokolov, Mikhail D Dokukin, Giorgos Mountrakis, Virginia Ruiz-Villanueva, Markus Stoffel
Climate change has been shown to increase the number of mountain lakes across various mountain ranges in the World. In Central Asia, and in particular on the territory of Uzbekistan, a detailed assessment of glacier lakes and their evolution over time is, however lacking. For this reason we created the first detailed inventory of mountain lakes of Uzbekistan based on recent (2002-2014) satellite observations using WorldView-2, SPOT5, and IKONOS imagery with a spatial resolution from 2 to 10m. This record was complemented with data from field studies of the last 50years...
March 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28319701/tracking-effluent-discharges-in-undisturbed-stony-soil-and-alluvial-gravel-aquifer-using-synthetic-dna-tracers
#9
Liping Pang, Beth Robson, Kata Farkas, Erin McGill, Arvind Varsani, Lea Gillot, Jinhua Li, Phillip Abraham
With the intensification of human activities, fresh water resources are increasingly being exposed to contamination from effluent disposal to land. Thus, there is a greater need to identify the sources and pathways of water contamination to enable the development of better mitigation strategies. To track discharges of domestic effluent into soil and groundwater, 10 synthetic double-stranded DNA (dsDNA)(3) tracers were developed in this study. Laboratory column experiment and field groundwater and soil lysimeter studies were carried out spiking DNA with oxidation-pond domestic effluent...
March 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28319661/atomistic-insights-into-nucleation-and-formation-of-hexagonal-boron-nitride-on-ni-from-first-principles-based-reactive-molecular-dynamics-simulations
#10
Song Liu, Adri C T van Duin, Diana M van Duin, Bin Liu, James H Edgar
Atomistic-scale insights into the growth of a continuous, atomically thin hexagonal boron nitride (hBN) lattice from elemental boron and nitrogen on Ni substrates were obtained from multi-scale modeling combining density functional theory (DFT) and reactive molecular dynamics (rMD). The quantum mechanical calculations focused on the adsorption and reaction energetics for the hBN building-block species, i.e., atomic B, N, BxNy (x, y = 1-2), on Ni(111) and Ni(211), and the diffusion pathways of elemental B and N on these slab model surfaces and in the sublayer...
March 20, 2017: ACS Nano
https://www.readbyqxmd.com/read/28319659/improving-computational-predictions-of-single-stranded-rna-tetramers-with-revised-%C3%AE-%C3%AE-torsional-parameters-for-the-amber-force-field
#11
David J Wales, Ilyas Yildirim
With current advancements in RNA based therapeutics, it is becoming crucial to utilize theoretical and computational methods to describe properly the physical properties of RNA molecules. NMR and X-ray crystallography are two powerful techniques for investigating structural properties. However, if the RNA molecules are complex or dynamic, these methods might not be adequate. For computational approaches, the quality of the force field will determine accuracy of our predictions. In this contribution, we revise the α/γ torsional parameters of RNA for amber force field using a model system representing an RNA dimer backbone...
March 20, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28319650/-monoclonal-antibodies-in-the-treatment-of-ms-emergence-of-b-cell-targeted-therapies
#12
REVIEW
Ai-Lan Nguyen, Melissa Gresle, Tessa Marshall, Helmut Butzkueven, Judith Field
Multiple sclerosis (MS) is a chronic inflammatory disease of the CNS, and one of the most common causes of disability in young adults. Over the last decade, new disease modifying therapies have rapidly emerged, including monoclonal antibodies (mAbs) that have provided highly targeted therapies with superior efficacy compared to platform therapies. In particular, monoclonal antibodies directed against CD20-positive B cells have shown remarkable results in recent clinical trials, and renewed interest in the mechanism of B-cell depleting therapies to ameliorate relapse activity and progression in MS...
March 20, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28319560/rash-diagnostics-an-update-on-the-diagnosis-of-allergic-rashes
#13
Corinne Savides Happel
PURPOSE OF REVIEW: The purpose of this review is to summarize recent research regarding the diagnosis of allergic rashes and to suggest future directions for the promotion of accurate diagnosis and endotype specification. RECENT FINDINGS: Multiple cohort studies demonstrate that with appropriate clinical evaluation, drug allergy labels can be removed in up to 90% of cases. Genetic tests can predict severe adverse cutaneous drug reactions in some cases and in vitro tests are being sought to identify causative drugs in others...
March 17, 2017: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/28319548/tanshinone-iia-attenuates-sevoflurane-neurotoxicity-in-neonatal-mice
#14
Yimeng Xia, Heng Xu, Chenfei Jia, Xiaodong Hu, Yu Kang, Xiaoxuan Yang, Qingsheng Xue, Guorong Tao, Buwei Yu
BACKGROUND: Sevoflurane is the most widely used inhalational anesthetic in pediatric medicine. Despite this, sevoflurane has been reported to exert potentially neurotoxic effects on the developing brain. Clinical interventions and treatments for these effects are limited. Tanshinone IIA (Tan IIA), extracted from Salvia miltiorrhiza (Danshen), has been documented to alleviate cognitive decline in traditional applications. Therefore, we hypothesized that preadministration of Tan IIA may attenuate sevoflurane-induced neurotoxicity, suggesting that Tan IIA is a new and promising drug capable of counteracting the effects of cognitive dysfunction produced by general anesthetics...
April 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28319462/late-effects-of-exposure-to-ionizing-radiation-and-age-on-human-thymus-morphology-and-function
#15
Reiko Ito, Laura P Hale, Susan M Geyer, Jie Li, Andrew Sornborger, Junko Kajimura, Yoichiro Kusunoki, Kengo Yoshida, Marcel R M van den Brink, Seishi Kyoizumi, Nancy R Manley, Kei Nakachi, Gregory D Sempowski
The thymus is essential for proper development and maintenance of a T-cell repertoire that can respond to newly encountered antigens, but its function can be adversely affected by internal factors such as pregnancy and normal aging or by external stimuli such as stress, infection, chemotherapy and ionizing radiation. We have utilized a unique archive of thymus tissues, obtained from 165 individuals, exposed to the 1945 atomic bomb blast in Hiroshima, to study the long-term effects of receiving up to ∼3 Gy dose of ionizing radiation on human thymus function...
March 20, 2017: Radiation Research
https://www.readbyqxmd.com/read/28319452/the-state-of-the-otolaryngology-match-a-review-of-applicant-trends-impossible-qualifications-and-implications
#16
Sarah N Bowe, Cecelia E Schmalbach, Adrienne M Laury
Objective This State of the Art Review aims (1) to define recent qualifications of otolaryngology resident applicants by focusing on United States Medical Licensing Examination (USMLE) scores, Alpha Omega Alpha (AOA) status, and research/publications and (2) to summarize the current literature regarding the relationship between these measures and performance in residency. Data Sources Electronic Residency Application Service, National Residency Matching Program, PubMed, Ovid, and GoogleScholar. Review Methods Electronic Residency Application Service and National Residency Matching Program data were analyzed to evaluate trends in applicant numbers and qualifications...
March 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28319391/synthesis-isotopic-enrichment-and-solid-state-nmr-characterization-of-zeolites-derived-from-the-assembly-disassembly-organisation-reassembly-process
#17
Giulia P M Bignami, Daniel M Dawson, Valerie R Seymour, Paul S Wheatley, Russell Edward Morris, Sharon E Ashbrook
The great utility and importance of zeolites in fields as diverse as industrial catalysis and medicine has driven considerable interest in the ability to target new framework types with novel properties and applications. The recently-introduced and unconventional Assembly, Disassembly, Organization, Reassembly (ADOR) method represents one exciting new approach to obtain solids with targeted structures by selectively disassembling pre-prepared hydrolytically-unstable frameworks, and then reassembling the resulting products to form materials with new topologies...
March 20, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28319366/magnetic-printing-of-a-biosensor-inexpensive-rapid-sensing-to-detect-picomolar-amounts-of-antigen-with-antibody-functionalized-carbon-nanotubes
#18
Abdel Rahman Abdel Fattah, Ahmed M Abdalla, Sarah Mishriki, Elvira Meleca, Fei Geng, Suvojit Ghosh, Ishwar K Puri
When an antibody (Ab) is immobilized on its surface, a carbon nanotube (CNT) becomes a biosensor that detects the corresponding antigen (Ag) since Ag-Ab complexes formed on the CNT surface moderate the current flow through it. We synthesize a biological ink containing CNTs that are twice functionalized, first with magnetic nanoparticles (MNPs) and thereafter with the anti-c-Myc monoclonal Ab. The ink is pipetted and dynamically self organized by an external magnetic field into a dense electrically conducting sensor strip that measures the decrease in current when a sample containing c-Myc Ag is deposited on it...
March 20, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28319363/real-time-observation-of-the-electrode-size-dependent-evolution-dynamics-of-the-conducting-filaments-in-a-sio2-layer
#19
Fang Yuan, Zhi Zhang, Chunru Liu, Feichi Zhou, Hei Man Yau, Wei Lu, Xiaoyan Qiu, H-S Philip Wong, Jiyan Dai, Yang Chai
Conducting Bridge Random Access Memory (CBRAM) is one of the most promising candidates for future non-volatile memories. It is important to understand the scalability and retention of CBRAM cells to realize better memory performance. Here we directly observe the switching dynamics of Cu tip/SiO2/W cells with various active electrode sizes using in-situ transmission electron microscopy. Conducting filaments (CFs) grow from the active electrode (Cu tip) to inert electrode (W) during the SET operations. The size of the Cu tip affects the electric-field distribution, the amount of the cation injection into electrolyte, and the dimension of the CF...
March 20, 2017: ACS Nano
https://www.readbyqxmd.com/read/28319324/future-of-robotic-surgery-in-urology
#20
Jens J Rassweiler, Riccardo Autorino, Jan Klein, Alex Mottrie, Ali Serdar Goezen, Jens-Uwe Stolzenburg, Koon H Rha, Marc Schurr, Jihad Kaouk, Vipul Patel, Prokar Dasgupta, Evangelos Liatsikos
OBJECTIVES: To provide a comprehensive overview of the current status and future perspectives in the field of robotic systems for urologic surgery. MATERIALS AND METHODS: A non-systematic literature review was performed by using PubMed / Medline search electronic engines. Existing patents for robotic devices were researched using the Google search machine. Findings were critically analyzed also by taking into account personal experience of the authors. RESULTS: Relevant patents of the first generation of the da Vinci platform will expire in 2019...
March 20, 2017: BJU International
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