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Vestibulitis

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https://www.readbyqxmd.com/read/29155208/inflammatory-renin-angiotensin-system-disruption-attenuates-sensory-hyperinnervation-and-mechanical-hypersensitivity-in-a-rat-model-of-provoked-vestibulodynia
#1
Anuradha Chakrabarty, Zhaohui Liao, Ying Mu, Peter G Smith
Vestibulodynia is characterized by peri-vaginal mechanical hypersensitivity, hyperinnervation, and abundant inflammatory cells expressing renin-angiotensin system proteins. We developed a tractable rat model of vestibulodynia to further assess the contributions of the renin-angiotensin system. Complete Freund's adjuvant (CFA) injected into the posterior vestibule induced marked vestibular hypersensitivity throughout a 7-day test period. Numbers of axons immunoreactive for PGP9.5, calcitonin gene-related peptide, and GFRα2 were increased...
November 15, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29144056/oropharyngeal-dysphagia-profiles-in-individuals-with-oculopharyngeal-muscular-dystrophy
#2
L C Tabor, E K Plowman, C Romero-Clark, S Youssof
BACKGROUND: Although dysphagia represents a hallmark manifestation of oculopharyngeal muscular dystrophy (OPMD), limited knowledge exists regarding the underlying nature of oropharyngeal swallowing impairments in this patient population. We aimed to delineate global pharyngeal dysphagia profiles in OPMD and identify the prevalence and physiologic associations of impairments in swallowing safety and efficiency. METHODS: Twenty-two individuals with OPMD completed a videofluoroscopic swallowing evaluation...
November 16, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/29117653/effect-of-delivery-and-episiotomy-on-the-emergence-of-urinary-incontinence-in-women-review-of-literature
#3
Krešimir Živković, Nikica Živković, Tomislav Župić, Damir Hodžić, Vjekoslav Mandić, Slavko Orešković
Episiotomy is obstetric procedure during which the incision extends the vestibule of the vagina during the second stage of labor. Episiotomy was extensively spread with gradual increase of rates in the first half of the 20th century and was performed medio-laterally in all nulliparous women with the idea to protect fetal head from trauma and pelvic floor from injuries. However, reports claiming that episiotomy had no such benefits were published. It was shown that routine medio-lateral episiotomy did not protect against the appearance of urinary incontinence after vaginal delivery, while the risk of anal incontinence could be increased...
December 2016: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29105767/the-relationship-between-endolymphatic-hydrops-in-the-vestibule-and-low-frequency-air-bone-gaps
#4
Satofumi Sugimoto, Tadao Yoshida, Masaaki Teranishi, Yuriko Okazaki, Shinji Naganawa, Michihiko Sone
OBJECTIVES/HYPOTHESIS: To investigate the relationship between endolymphatic hydrops and hearing level, focusing on significant vestibular endolymphatic hydrops adjacent to the stapes footplate and low-frequency air-bone gaps. STUDY DESIGN: Retrospective study. METHODS: The study included 1,548 ears from 775 patients who underwent magnetic resonance imaging examination in our university hospital to investigate possible endolymphatic hydrops between January 2012 and December 2015...
November 6, 2017: Laryngoscope
https://www.readbyqxmd.com/read/29099441/mastoid-and-inner-ear-measurements-in-patients-with-meni%C3%A3-re-s-disease
#5
Eric M Sugihara, Alexander L Marinica, Nathan D Vandjelovic, Benjamin M Kelley, Said S Sana, Nicholas E Starkey, Seilesh C Babu
OBJECTIVE: To determine the relationship between radiographic temporal bone anatomy of patients with Menière's disease in medically and surgically managed populations versus controls. STUDY DESIGN: Retrospective chart review. SETTING: Two tertiary referral centers. PATIENTS: Adults older than 18 years with Menière's disease treated with endolymphatic sac decompression (ESD) or medical management (non-ESD) versus controls...
December 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29098648/a-75-year-old-woman-presenting-with-nasal-vestibulitis
#6
Annalisa Saracino, Francesco Fortarezza, Danila Costa, Domenico Bonamonte
No abstract text is available yet for this article.
November 2, 2017: Infection
https://www.readbyqxmd.com/read/29089218/-how-to-manage-vertigo-in-adult
#7
Hella Vuong Chaney, Dominique Rohmer, Anne Charpiot
The interrogation and the clinical examination are critical in the research of vertigo etiology. In the context of vertigo, the vital emergencies are of neurological and vascular origins. It is therefore necessary to be able to identify them quickly and simply. Vertigo is a symptom to relieve and the cause is to be diagnosed. Careful questioning combined with neurological examination, nystagmus study, Halmagyi test and skew deviation search are more reliable than imaging in the first 48hours to detect a stroke...
October 28, 2017: La Presse Médicale
https://www.readbyqxmd.com/read/29069569/the-glpf-residue-trp219-is-part-of-an-amino-acid-cluster-crucial-for-aquaglyceroporin-oligomerization-and-function
#8
Margareta Trefz, Rebecca Keller, Miriam Vogt, Dirk Schneider
The vestibule loop regions of aquaglyceroporins are involved in accumulation of glycerol inside the channel pore. Even though most loop regions do not show high sequence similarity among aquaglyceroporins, loop E is highly conserved in aquaglyceroporins, but not in members of the homologous aquaporins. Specifically, a tryptophan residue is extremely conserved within this loop. We have investigated the role of this residue (Trp219) that deeply protrudes into the protein and potentially interacts with adjacent loops, using the E...
October 22, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29057133/a-rare-case-of-recurrent-mucoepidermoid-carcinoma-of-the-nasal-vestibule
#9
Vladimir Bedeković, Miro Leventić, Boris Jelavić, Robert Trotić, Mihael Ries, Mirjana Kostić, Tomislav Lauc
We report a rare case of a large recurrent mucoepidermoid carcinoma (RMEC) in an 81-year-old female smoker, which has originated in the right nasal vestibule. The recurrent tumour was inadequately treated for 6 years. It was a slow-growing tumour for 3 years and then began to enlarge at a higher pace. In the next three years it has covered a large part of the face. The patient had refused any medical treatment. The tumour caused breathing and swallowing difficulties. Because of the profuse bleeding from the tumour, the patient underwent emergency surgery...
2017: Case Reports in Oncological Medicine
https://www.readbyqxmd.com/read/29043479/altered-auditory-and-vestibular-functioning-in-individuals-with-low-bone-mineral-density-a-systematic-review
#10
REVIEW
Niraj Kumar Singh, Raghav Hira Jha, Aditi Gargeshwari, Prawin Kumar
Alteration in the process of bone remodelling is associated with falls and fractures due to increased bone fragility and altered calcium functioning. The auditory system consists of skeletal structures and is, therefore, prone to getting affected by altered bone remodelling. In addition, the vestibule consists of huge volumes of calcium (CaCO3) in the form of otoconia crystals and alteration in functioning calcium levels could, therefore, result in vestibular symptoms. Thus, the present study aimed at compiling information from various studies on assessment of auditory or vestibular systems in individuals with reduced bone mineral density (BMD)...
October 17, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29028846/periodontal-indices-and-status-in-34-growing-patients-with-unilateral-cleft-lip-and-palate-a-split-mouth-study
#11
Paweł Plakwicz, Beata Wyrębek, Renata Górska, Dorota Cudziło
Periodontal examination in growing patients with unilateral cleft lip and palate was performed in a split-mouth study design. Higher plaque acumulation and bleeding indices were recorded for teeth on the cleft side. Pocket probing depth (PPD) and clinical attachment level (CAL) values were higher at lateral incisors and canines adjacent to the cleft. Keratinized gingiva and depth of the vestibule were lower adjacent to the cleft. This study shows that growing patients with clefts present differences regarding periodontal parameters between the cleft and the control side...
November 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/29019934/a-massively-parallel-sequence-similarity-search-for-metagenomic-sequencing-data
#12
Masanori Kakuta, Shuji Suzuki, Kazuki Izawa, Takashi Ishida, Yutaka Akiyama
Sequence similarity searches have been widely used in the analyses of metagenomic sequencing data. Finding homologous sequences in a reference database enables the estimation of taxonomic and functional characteristics of each query sequence. Because current metagenomic sequencing data consist of a large number of nucleotide sequences, the time required for sequence similarity searches account for a large proportion of the total time. This time-consuming step makes it difficult to perform large-scale analyses...
October 11, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28991328/-nasal-phaeohyphomycosis-by-curvularia-spicifera-in-pediatric-patient-with-neutropenia-and-acute-myeloid-leukemia
#13
Constanza Bay, Tamara González, Gonzalo Munoz, Paulette Legarraga, Cecilia Vizcaya, Katia Abarca
There are very few reports of pediatric patients with infections by dematiaceous filamentous fungi. In this publication we report a case of invasive fungal infection of the nasal septum by Curvularia spicifera in a pediatric patient with acute myeloid leukemia. The patient presented with a painful scabby wound in the nasal vestibule. Culture and universal PCR were consistent with Curvularia spicifera. Early management with surgical debridement and bi-associated antifungal therapy achieved complete resolution of the lesions, with no evidence of dissemination and relapses...
June 2017: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/28979166/provoked-vestibulodynia-current-perspectives
#14
REVIEW
Helen Henzell, Karen Berzins, Jennifer P Langford
Provoked vestibulodynia (PVD) refers to vulvar pain of at least 3 months duration, localized to the vestibule, provoked by touch and sexual activity and occurring in the absence of a clear identifiable cause. The clinical spectrum ranges from mild with distressing discomfort through to severe and disabling pain. Current understanding is that PVD is one of many chronic pain conditions characterized by sensitization of peripheral and central nociceptive pathways, with pain arising due to dysfunctional neuronal activity in the absence of painful stimuli...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/28970071/low-level-laser-therapy-for-the-treatment-of-provoked-vestibulodynia-a-randomized-placebo-controlled-pilot-trial
#15
Ahinoam Lev-Sagie, Asia Kopitman, Amnon Brzezinski
BACKGROUND: Low-level laser therapy (LLLT) is an emerging medical technology in which non-thermal laser irradiation is applied to treat pain. Because LLLT has been found effective in treating various pain syndromes without known side effects, we conducted a study evaluating the effect of LLLT on provoked vestibulodynia (PVD), a complex sexual pain disorder characterized by pain confined to the vulvar vestibule in response to contact or pressure. AIM: To investigate the effectiveness of LLLT for PVD in a randomized, placebo-controlled, double-blinded trial...
September 29, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28969192/effect-of-2-nasal-mupirocin-ointment-on-decreasing-complications-of-nasotracheal-intubation-a-randomized-controlled-trial
#16
Kourosh Taheri Talesh, Reza Movassaghi Gargary, Seyed Ahmad Arta, Javad Yazdani, Monireh Roshandel, Milad Ghanizadeh, Hossein Samadi Kafil, Mir Naser Seyyed Mousavi
INTRODUCTION: In oral and maxillofacial surgeries, nasotracheal intubation is carried out to increase the surgeon's access to the oral cavity. During nasotracheal intubation the risk of trauma is higher than that in orotracheal intubation as there is passage of the tube through the mucosa of the nasal tract due to which bacteria might get transported into the trachea. AIM: To evaluate the effect of 2% nasal mupirocin ointment before and after nasotracheal intubation on decreasing the complications of intubation for oral and maxillofacial surgeries...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28966463/sinonasal-and-laryngeal-sarcoidosis
#17
Hawa Edriss, John Kelley, Joshua Demke
Sarcoidosis is a chronic granulomatous inflammation of uncertain etiology that can involve any organ system in the body. Sinonasal and laryngeal involvement is rare, poorly understood, and difficult to diagnose. Additionally, the extent of the disease is variable, and the response to systemic corticosteroids is often poor. We report a case of a 55-year-old woman with prior cutaneous sarcoidosis who presented with chronic nasal congestion, difficulty breathing, dysphonia, and stridor, and biopsy of the nasal vestibule revealed noncaseating granulomatous inflammation...
October 2017: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/28960404/histochemical-and-surface-ultrastructural-characteristics-of-the-nasal-cavity-of-laughing-dove
#18
S M Farouk, S A Hassan, M A Emam
Ten apparently healthy, adult laughing doves were used to document detailed histological, histochemical and surface ultrastructural features of the nasal cavity and to investigate the structure-function relationship of the nasal cavity in this species. We observed that the nasal cavity of the laughing dove was composed of three main regions: nasal vestibule, respiratory and olfactory. Each region presented a characteristic epithelial lining. The epithelium varied along the nasal vestibule from keratinized stratified squamous rostrally to non-keratinized stratified squamous in the middle and stratified cuboidal in the caudal region of the nasal vestibule...
September 27, 2017: Anatomia, Histologia, Embryologia
https://www.readbyqxmd.com/read/28953145/lipoma-on-the-lower-lip
#19
Tiago Gai Aita, João Paulo Bonardi, Gaykon Alex Vitti Stabile, Cecilia Luiz Pereira-Stabile, Leonardo Perez Faverani, Eduardo Hochuli-Vieira
Lipoma is a benign tumor of fat tissue, found frequently in subcutaneous tissues. However, oral manifestations are relatively rare. The present patient illustrates the successful treatment of a lipoma treated by complete excision of the lesion. A female patient, 75 years old, presenting lesion in the right oral vestibule where excisional biopsy was performed. The professional must diagnose this type of injury as soon as possible and treat it so that it does not take large proportions, which can result in esthetic and functional sequelae to the patient...
November 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28953132/human-papillomavirus-associated-adenocarcinoma-in-situ-of-the-vestibule
#20
Karen L Talia, Geoffrey Otton, Suzanne Garland, Samuel Phillips, James Scurry
No abstract text is available yet for this article.
October 2017: Journal of Lower Genital Tract Disease
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