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https://www.readbyqxmd.com/read/28638373/interactions-between-food-additive-silica-nanoparticles-and-food-matrices
#1
Mi-Ran Go, Song-Hwa Bae, Hyeon-Jin Kim, Jin Yu, Soo-Jin Choi
Nanoparticles (NPs) have been widely utilized in the food industry as additives with their beneficial characteristics, such as improving sensory property and processing suitability, enhancing functional and nutritional values, and extending shelf-life of foods. Silica is used as an anti-caking agent to improve flow property of powered ingredients and as a carrier for flavors or active compounds in food. Along with the rapid development of nanotechnology, the sizes of silica fall into nanoscale, thereby raising concerns about the potential toxicity of nano-sized silica materials...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28631133/bone-density-in-pediatric-crohn-s-disease-a-cross-sectional-observation-from-south-india
#2
Shiraz Salim Khan, Sagar S Patil
BACKGROUND: Crohn's disease (CD) frequently manifests in the second and third decades of life. Malnutrition and corticosteroid therapy may affect bone mineralization and delay bone growth. Our aim was to study bone mineral density and factors associated low bone mineral density (BMD) in pediatric CD. METHODS: A cross-sectional observational study in children with CD (aged 5 to <18 years) was done. Demographic and treatment details were noted. Vitamin D levels <20 ng/mL were considered as deficiency...
June 20, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28611442/competing-factors-link-to-bone-health-in-polycystic-ovary-syndrome-chronic-low-grade-inflammation-takes-a-toll
#3
Shirin Kalyan, Millan S Patel, Elaine Kingwell, Hélène C F Côté, Danmei Liu, Jerilynn C Prior
Chronic inflammation predisposes to poor bone health. Women with polycystic ovary syndrome (PCOS) experience androgen excess, ovulatory disturbances, insulin resistance, abdominal adiposity and chronic inflammation. Our objective was to investigate the relationships among bone health parameters, chronic subclinical inflammation and anthropometric measures in premenopausal women with and without PCOS. In 61 premenopausal women, 22 women with PCOS and 39 controls, we assessed bone parameters (total hip bone mineral density [BMD] by dual-energy X-ray absorptiometry and radius strength-strain index [SSI] by peripheral quantitative computed tomography), inflammation (C-reactive protein/albumin), oxidative stress (leukocyte telomere length, urinary 8-hydroxydeoxyguanosine); hemoglobin A1c; anthropometric measures (body mass index, waist-to-height ratio, cross-sectional muscle area)...
June 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28609642/micronutrient-deficiencies-after-bariatric-surgery-an-emphasis-on-vitamins-and-trace-minerals
#4
Jayshil J Patel, Manpreet S Mundi, Ryan T Hurt, Bruce Wolfe, Robert G Martindale
Obesity has become a worldwide epidemic with a disproportionate increase in grade III obesity. Bariatric surgery offers an attractive option for sustained weight loss compared with traditional methods such as exercise and diet. Micronutrient deficiencies are common and clinically significant after bariatric surgery. These deficiencies are related to a combination of patient and surgical variables. A thorough understanding of specific micronutrient deficiencies is necessary for early recognition and optimal management...
June 1, 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/28587067/diet-induced-low-grade-metabolic-acidosis-and-clinical-outcomes-a-review
#5
Renata Alves Carnauba, Ana Beatriz Baptistella, Valéria Paschoal, Gilberti Helena Hübscher
Low-grade metabolic acidosis is a condition characterized by a slight decrease in blood pH, within the range considered normal, and feeding is one of the main factors that may influence the occurrence of such a condition. The excessive consumption of acid precursor foods (sources of phosphorus and proteins), to the detriment of those precursors of bases (sources of potassium, calcium, and magnesium), leads to acid-base balance volubility. If this condition occurs in a prolonged, chronic way, low-grade metabolic acidosis can become significant and predispose to metabolic imbalances such as kidney stone formation, increased bone resorption, reduced bone mineral density, and the loss of muscle mass, as well as the increased risk of chronic diseases such as type 2 diabetes mellitus, hypertension, and non-alcoholic hepatic steatosis...
May 25, 2017: Nutrients
https://www.readbyqxmd.com/read/28584418/comparison-of-osteogenic-potential-of-poly-ether-ether-ketone-with-titanium-coated-poly-ether-ether-ketone-and-titanium-blended-poly-ether-ether-ketone-an-in-vitro-study
#6
T Anjan Kumar, J Brintha Jei, B Muthukumar
STATEMENT OF PROBLEM: Poly-ether-ether-ketone (PEEK), a high-performance semi-crystalline thermoplastic polymer, has been employed to replace the metallic implant components in orthopedics. There were various studies performed in accordance to medical grade PEEK, but the relationship between titanium dioxide (TiO2)-coated PEEK, TiO2-blended PEEK, and untreated PEEK still remains complicated, even undefined. PURPOSE: The purpose of this study was to compare and quantify the osteogenic potential of untreated PEEK, TiO2-coated PEEK and TiO2-blended PEEK...
April 2017: Journal of Indian Prosthodontic Society
https://www.readbyqxmd.com/read/28570093/predicting-future-hip-fractures-on-routine-abdominal-ct-using-opportunistic-osteoporosis-screening-measures-a-matched-case-control-study
#7
Scott J Lee, Paul A Anderson, Perry J Pickhardt
OBJECTIVE: Hip fracture is a major consequence of low bone mineral density, which is treatable but underdiagnosed. The purpose of this case-control study is to determine whether lumbar vertebral trabecular attenuation, vertebral compression fractures, and femoral neck T scores readily derived from abdominopelvic CT scans obtained for various indications are associated with future hip fragility fracture. MATERIALS AND METHODS: A cohort of 204 patients with hip fracture (130 women and 74 men; mean age, 74...
June 1, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28560501/relationship-of-bone-mineral-density-with-valvular-and-annular-calcification-in-community-dwelling-older-people-the-cardiovascular-health-study
#8
Daniele Massera, Shuo Xu, Traci M Bartz, Anna E Bortnick, Joachim H Ix, Michel Chonchol, David S Owens, Eddy Barasch, Julius M Gardin, John S Gottdiener, John R Robbins, David S Siscovick, Jorge R Kizer
Associations between bone mineral density and aortic valvular, aortic annular, and mitral annular calcification were investigated in a cross-sectional analysis of a population-based cohort of 1497 older adults. Although there was no association between continuous bone mineral density and outcomes, a significant association between osteoporosis and aortic valvular calcification in men was found. INTRODUCTION: The process of cardiac calcification bears a resemblance to skeletal bone metabolism and its regulation...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28560474/vertebral-fracture-in-postmenopausal-chinese-women-a-population-based-study
#9
L Cui, L Chen, W Xia, Y Jiang, L Cui, W Huang, W Wang, X Wang, Y Pei, X Zheng, Q Wang, Z Ning, M Li, O Wang, X Xing, Q Lin, W Yu, X Weng, L Xu, S R Cummings
In a random sample of postmenopausal Chinese women, the prevalence of radiographic vertebral fractures increased from 13% between ages 50 and 59 to over 50% after age 80 years. A model with seven clinical risk factors predicted the probability of vertebral fractures as well with as without BMD and better than a model with only three risk factors. More than half an hour of outdoor activity per day might correlate with lower risk of vertebral fracture in this population. INTRODUCTION: We aimed to describe the prevalence and develop a model for prediction of radiographic vertebral fractures in a large random sample of postmenopausal Chinese women...
May 30, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28552661/30years-of-dxa-technology-innovations
#10
Claus-C Glüer
As the successor of Dual Photon Absorptiometry (DPA), Dual X-ray Absorptiometry (DXA) has seen 30years of continuous technological innovations. Implementation of measures for standardization and quality assurance made DXA a reliable and clinically useful approach. Its use in clinical multicenter drug studies in osteoporosis lead to general acceptance as the standard technique of bone densitometry. The limitations of DXA are well established. As a measure of areal bone mineral density (aBMD) it depends on bone size and is biased by overlaying soft tissue and calcified structures...
May 24, 2017: Bone
https://www.readbyqxmd.com/read/28539676/results-from-polish-spondyloarthritis-initiative-registry-polspi-methodology-and-data-from-the-first-year-of-observation
#11
Zofia Guła, Tacjana Barczyńska, Marek Brzosko, Jerzy Gąsowski, Sławomir Jeka, Katarzyna Jodłowska-Cicio, Beata Kwaśny-Krochin, Piotr Leszczyński, Łukasz Lubiński, Katarzyna Łosińska, Katarzyna Pawlak-Buś, Hanna Przepiera-Będzak, Włodzimierz Samborski, Małgorzata Schlabs, Maciej Siedlar, Dorota Sikorska, Jerzy Świerkot, Małgorzata Węgierska, Piotr Wiland, Mariusz Korkosz
OBJECTIVES: Report on one-year results from the Polish Spondyloarthritis Initiative registry (PolSPI), containing the cross-sectional analysis of clinical and imaging data as well as database methodology. MATERIAL AND METHODS: The PolSPI registry includes patients with axial (axSpA) and peripheral (perSpA) spondyloarthritis according to ASAS classification criteria, and/or patients with ankylosing spondylitis according to modified New York criteria, psoriatic arthritis according to CASPAR criteria, arthropathy in inflammatory bowel disease, reactive arthritis, juvenile spondyloarthritis or undifferentiated spondyloarthritis...
2017: Reumatologia
https://www.readbyqxmd.com/read/28525528/sevelamer-versus-calcium-based-phosphate-binders-for-chronic-kidney-disease
#12
Gonzalo A Bravo-Soto, Trinidad Madrid
Chronic kidney disease-mineral and bone disorder is prevalent. There is controversy regarding whether calcium-based phosphate binders or sevelamer - a non-calcium phosphate binder – constitute a better therapeutic alternative. Searching in Epistemonikos database, which is maintained by screening multiple information sources, we identified 12 systematic reviews comprising 61 studies of which 41 correspond to randomized trials addressing the question of this article. We combined the evidence using meta-analysis and generated a summary of findings following the GRADE approach...
May 12, 2017: Medwave
https://www.readbyqxmd.com/read/28518221/micronutrient-supplementation-in-adults-with-hiv-infection
#13
REVIEW
Marianne E Visser, Solange Durao, David Sinclair, James H Irlam, Nandi Siegfried
BACKGROUND: Micronutrient deficiencies are common among adults living with HIV disease, particularly in low-income settings where the diet may be low in essential vitamins and minerals. Some micronutrients play critical roles in maintenance of the immune system, and routine supplementation could therefore be beneficial. This is an update of a Cochrane Review previously published in 2010. OBJECTIVES: To assess whether micronutrient supplements are effective and safe in reducing mortality and HIV-related morbidity of HIV-positive adults (excluding pregnant women)...
May 18, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28508265/incidence-of-vertebral-fractures-in-women-with-systemic-lupus-erythematosus-after-8-years-of-follow-up
#14
Mario García-Carrasco, Claudia Mendoza-Pinto, María de la Luz León-Vázquez, Socorro Méndez-Martínez, Ivet Etchegaray-Morales, Álvaro Montiel-Jarquín, Miguel Angel Enriquez-Guerra, Margarita Muñóz-Guarneros, José Luis Gálvez-Romero, Pamela Soto-Santillán, Ricard Cervera
The aim of this study was to evaluate possible associations between potential risk factors and the occurrence of established vertebral fractures (VF) in Mexican patients with systemic lupus erythematosus (SLE). Consecutive patients with SLE were enrolled in a prospective, observational study from 2006 to 2015. Information on potential risk factors, including demographics, clinical data, and bone mineral density (BMD) at the lumbar spine and hip on dual-energy X-ray absorptiometry was collected at baseline and follow-up...
May 15, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/28508244/interventions-for-the-endodontic-management-of-non-vital-traumatised-immature-permanent-anterior-teeth-in-children-and-adolescents-a-systematic-review-of-the-evidence-and-guidelines-of-the-european-academy-of-paediatric-dentistry
#15
REVIEW
M Duggal, H J Tong, M Al-Ansary, W Twati, P F Day, H Nazzal
AIM: This systematic review was undertaken in order to develop guidelines for the European Academy of Paediatric Dentistry for the management of non-vital permanent anterior teeth with incomplete root development. METHODS: Three techniques were considered; apexification by single or multiple applications of calcium hydroxide, use of Mineral Trioxide Aggregate (MTA) for the creation of an apical plug followed by obturation of the root canal, and finally a Regenerative Endodontic Technique (RET)...
May 15, 2017: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/28489278/growth-of-indoor-fungi-on-gypsum
#16
Frank J J Segers, Karel A van Laarhoven, Han A B Wösten, Jan Dijksterhuis
AIMS: To have a better understanding of fungal growth on gypsum building materials to prevent indoor fungal growth. METHODS AND RESULTS: Gypsum is acquired by mining or as a by-product of flue-gas desulfurization or treatment of phosphate ore for the production of fertilizer. Natural gypsum, flue-gas gypsum, and phosphogypsum therefore have different mineral compositions. Here, growth of fungi on these types of gypsum was assessed. Conidia of the indoor fungi Aspergillus niger, Cladosporium halotolerans, and Penicillium rubens were inoculated and observed using microscopic techniques including low temperature scanning electron microscopy (Cryo-SEM)...
May 10, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28476202/periodontal-ligament-entheses-and-their-adaptive-role-in-the-context-of-dentoalveolar-joint-function
#17
REVIEW
Jeremy D Lin, Andrew T Jang, Michael P Kurylo, Jonathan Hurng, Feifei Yang, Lynn Yang, Arvin Pal, Ling Chen, Sunita P Ho
OBJECTIVE: The dynamic bone-periodontal ligament (PDL)-tooth fibrous joint consists of two adaptive functionally graded interfaces (FGI), the PDL-bone and PDL-cementum that respond to mechanical strain transmitted during mastication. In general, from a materials and mechanics perspective, FGI prevent catastrophic failure during prolonged cyclic loading. This review is a discourse of results gathered from literature to illustrate the dynamic adaptive nature of the fibrous joint in response to physiologic and pathologic simulated functions, and experimental tooth movement...
June 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28473075/acr-appropriateness-criteria-%C3%A2-osteoporosis%C3%A2-and%C3%A2-bone-mineral-density
#18
Robert J Ward, Catherine C Roberts, Jenny T Bencardino, Erin Arnold, Steven J Baccei, R Carter Cassidy, Eric Y Chang, Michael G Fox, Bennett S Greenspan, Soterios Gyftopoulos, Mary G Hochman, Douglas N Mintz, Joel S Newman, Charles Reitman, Zehava S Rosenberg, Nehal A Shah, Kirstin M Small, Barbara N Weissman
Osteoporosis is a considerable public health risk, with 50% of women and 20% of men >50 years of age experiencing fracture, with mortality rates of 20% within the first year. Dual x-ray absorptiometry (DXA) is the primary diagnostic modality by which to screen women >65 years of age and men >70 years of age for osteoporosis. In postmenopausal women <65 years of age with additional risk factors for fracture, DXA is recommended. Some patients with bone mineral density above the threshold for treatment may qualify for treatment on the basis of vertebral body fractures detected through a vertebral fracture assessment scan, a lateral spine equivalent generated from a commercial DXA machine...
May 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28472738/cartilage-lesions-in-feline-stifle-joints-associations-with-articular-mineralizations-and-implications-for-osteoarthritis
#19
Alexandra Leijon, Charles J Ley, Antonia Corin, Cecilia Ley
Feline stifle osteoarthritis (OA) is common, however little is known about the early stages of the disease. Furthermore, the importance of small articular mineralizations (AMs) in feline stifle OA is controversial. This study aimed to describe microscopic articular cartilage lesions and to investigate associations between cartilage lesions and AMs, synovitis, osteochondral junction findings and subchondral bone sclerosis. Stifles of 29 cats, aged 1-23years and euthanized for reasons other than stifle disease, were examined...
April 19, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28447308/determinants-of-stage-at-diagnosis-of-breast-cancer-in-nigerian-women-sociodemographic-breast-cancer-awareness-health-care-access-and-clinical-factors
#20
Elima Jedy-Agba, Valerie McCormack, Oluwole Olaomi, Wunmi Badejo, Monday Yilkudi, Terna Yawe, Emmanuel Ezeome, Iliya Salu, Elijah Miner, Ikechukwu Anosike, Sally N Adebamowo, Benjamin Achusi, Isabel Dos-Santos-Silva, Clement Adebamowo
PURPOSE: Advanced stage at diagnosis is a common feature of breast cancer in Sub-Saharan Africa (SSA), contributing to poor survival rates. Understanding its determinants is key to preventing deaths from this cancer in SSA. METHODS: Within the Nigerian Integrative Epidemiology of Breast Cancer Study, a multicentred case-control study on breast cancer, we studied factors affecting stage at diagnosis of cases, i.e. women diagnosed with histologically confirmed invasive breast cancer between January 2014 and July 2016 at six secondary and tertiary hospitals in Nigeria...
April 26, 2017: Cancer Causes & Control: CCC
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