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https://www.readbyqxmd.com/read/28223125/different-doses-of-strontium-ranelate-and-mechanical-vibration-modulate-distinct-responses-in-the-articular-cartilage-of-ovariectomized-rats
#1
A G H Mierzwa, J F Campos, M F Jesus, H B Nader, M Lazaretti-Castro, R D Reginato
OBJECTIVE: To investigate the effects of different strontium ranelate (SrR) doses alone or in combination with low-intensity and high-frequency mechanical vibration (MV) on articular cartilage in ovariectomized rats. DESIGN: Fifty 6-month-old female Wistar rats underwent ovariectomy and after three months were divided into: control group (Control); SrR 300mg/kg/day (SrR300); SrR 625mg/kg/day (SrR625); mechanical vibration (MV); SrR 625mg/kg/day plus MV (SrR625+MV)...
February 18, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28222408/severe-osteoporosis-with-multiple-spontaneous-vertebral-fractures-in-a-young-male-carrying-triple-polymorphisms-in-the-vitamin-d-receptor-collagen-type-1-and-low-density-lipoprotein-receptor-related-peptide-5-genes
#2
Maria P Yavropoulou, Panagoulia Kollia, Dimitris Chatzidimitriou, Stavroula Samara, Lemonia Skoura, John G Yovos
: Osteoporosis is a common disease with a strong genetic component. Several studies have reported the vitamin D receptor (VDR), collagen type I (COL1A1), and LDL receptor-related protein 5 (LRP5) genes as the most likely candidates. However, most of the studies have been carried out in postmenopausal women and older men and show inconsistent results. CASE PRESENTATION: We report a case of a 26-year old male who presented with severe back pain of acute onset, unrelated to any kind of trauma, and diffuse myalgia...
October 2016: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28210442/a-portable-fiber-optic-raman-spectrometer-concept-for-evaluation-of-mineral-content-within-enamel-tissue
#3
Anna Akkus, Shan Yang, Renato Roperto, Hathem Mustafa, Sorin Teich, Ozan Akkus
BACKGROUND: Measurement of tooth enamel mineralization using a clinically viable method is essential since variation of mineralization may be used to monitor caries risk or in assessing the effectiveness of remineralization therapy. Fiber optic Raman systems are becoming more affordable and popular in context of biomedical applications. However, the applicability of fiber optic Raman systems for measurement of mineral content within enamel tissue has not been elucidated significantly in the prior literature...
February 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28195085/histological-evaluation-of-the-possible-transformation-of-peripheral-giant-cell-granuloma-and-peripheral-ossifying-fibroma-a-preliminary-study
#4
Ömür Dereci, Şivge Akgün, Bülent Celasun, Adnan Öztürk, Ömer Günhan
AIMS: The objective of this study is to describe shared morphological features of peripheral giant cell granuloma (PGCG) and peripheral ossifying fibroma (POF) in detail and discuss the possible relationship between them. MATERIALS AND METHODS: Ten intermediate cases with features resembling to both POF and PGCG were selected and type 3 and 1 collagen immunostainings were performed for evaluation of the connective tissue maturation. Immunohistochemical staining percentage (SP) for stromal cells in the slides of POF and PGCG counterparts of intermediate lesions was scored as 1 when the SP was above 10%, 2 when the SP was above 25%, 3 when the SP was above 50% and 4 when the SP was above 75%...
January 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/28186942/use-of-combination-therapy-in-the-treatment-of-primary-osteoporosis-protocol-for-a-network-meta-analysis-of-randomised-trials
#5
Shenghan Lou, Houchen Lv, Yuxiang Chen, Licheng Zhang, Peifu Tang
INTRODUCTION: The existing medications approved for treatment of primary osteoporosis can be divided into antiresorptive drugs and anabolic drugs. According to the mechanisms of action, the combined therapy may produce a synergistic effect on bone mineral density (BMD) compared with monotherapy, and thus improves the efficacy of fracture resistance. This network meta-analysis aims to compare the efficacies of different combined methods for the treatment of primary osteoporosis. METHODS AND ANALYSIS: MEDLINE, EMBASE and Cochrane databases will be searched to identify all randomised controlled trials (RCTs) and quasi-RCTs that evaluate the effectiveness of combined therapy versus monotherapy for primary osteoporosis...
November 8, 2016: BMJ Open
https://www.readbyqxmd.com/read/28177351/effects-of-increasing-inclusion-of-sodium-hydroxide-treatment-on-growth-performance-carcass-characteristics-and-feeding-behavior-of-steers-fed-50-ddgs
#6
T B Freitas, A E Relling, M S Pedreira, W J B Rocha, A R Schroeder, T L Felix
Objectives were to determine the dietary inclusion level of NaOH in a dried distillers grains with solubles (DDGS)-based diet needed to improve growth performance and carcass characteristics of feedlot steers, and to determine the effects of NaOH treatment of DDGS on pattern of feed intake. Based on previous research regarding the acidity of DDGS, we hypothesized that using NaOH in cattle fed 50% DDGS-based diets to neutralize the acidity inherent in DDGS would improve growth performance of cattle but shift intake patterns...
January 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28175980/spine-fracture-prevalence-in-a-nationally-representative-sample-of-us-women-and-men-aged-%C3%A2-40-years-results-from-the-national-health-and-nutrition-examination-survey-nhanes-2013-2014
#7
F Cosman, J H Krege, A C Looker, J T Schousboe, B Fan, N Sarafrazi Isfahani, J A Shepherd, K D Krohn, P Steiger, K E Wilson, H K Genant
: Spine fracture prevalence is similar in men and women, increasing from <5 % in those <60 to 11 % in those 70-79 and 18 % in those ≥80 years. Prevalence was higher with age, lower bone mineral density (BMD), and in those meeting criteria for spine imaging. Most subjects with spine fractures were unaware of them. INTRODUCTION: Spine fractures have substantial medical significance but are seldom recognized. This study collected contemporary nationally representative spine fracture prevalence data...
February 7, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28129489/bone-mineral-density-and-the-risk-of-hip-and-knee-osteoarthritis-the-johnston-county-osteoarthritis-project
#8
Kamil E Barbour, Louise B Murphy, Charles G Helmick, Jennifer M Hootman, Jordan B Renner, Joanne M Jordan
OBJECTIVES: To address knowledge gaps regarding the relationship between bone mineral density (BMD) and incident hip or knee osteoarthritis (OA); specifically, lack of information regarding hip OA or symptomatic outcomes. METHODS: Using data (N=1,474) from the Johnston County Osteoarthritis (JoCo OA) Project's first (1999-2004) and second follow-up (2005-2010) of participants aged ≥45 years we examined the association between total hip BMD and both hip and knee OA...
January 27, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28108870/elucidating-the-interactions-and-phytotoxicity-of-zinc-oxide-nanoparticles-with-agriculturally-beneficial-bacteria-and-selected-crop-plants
#9
Anuraag Boddupalli, Rameshwar Tiwari, Anamika Sharma, Surender Singh, Radha Prasanna, Lata Nain
There is a growing interest in the use of bioinoculants to assist mineral fertilizers in improving crop production and yield. Azotobacter and Pseudomonas are two agriculturally relevant strains of bacteria which have been established as efficient bioinoculants. An experiment involving addition of graded concentrations of zinc oxide (ZnO) nanoparticles was undertaken using log phase cultures of Azotobacter and Pseudomonas. Growth kinetics revealed a clear trend of gradual decrease with Pseudomonas; however, Azotobacter exhibited a twofold enhancement in growth with increase in the concentration of ZnO concentration...
January 20, 2017: Folia Microbiologica
https://www.readbyqxmd.com/read/28105733/vitamin-d-supplementation-for-sickle-cell-disease
#10
REVIEW
Htoo Htoo Kyaw Soe, Adinegara Bl Abas, Nan Nitra Than, Han Ni, Jaspal Singh, Abdul Razzak Bin Mohd Said, Ifeyinwa Osunkwo
BACKGROUND: Sickle cell disease is a genetic chronic haemolytic and pro-inflammatory disorder. The clinical manifestations of sickle cell disease result from the presence of mutations on the beta globin genes that generate an abnormal haemoglobin product (called haemoglobin S) within the red blood cell. Sickle cell disease can lead to many complications such as acute chest syndrome, stroke, acute and chronic bone complications (including painful vaso-occlusive crisis, osteomyelitis, osteonecrosis and osteoporosis)...
January 20, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28064422/improved-detection-of-mineral-oil-toxicity-using-an-extended-mouse-embryo-assay
#11
Alessandra J Ainsworth, Jolene R Fredrickson, Dean E Morbeck
PURPOSE: Successful in vitro fertilization (IVF) relies on sound laboratory methods and culture conditions which depend on sensitive quality control (QC) testing. This study aimed to improve the sensitivity of mouse embryo assays (MEA) for detection of mineral oil toxicity. METHODS: Five experiments were conducted to study modifications of the standard mouse embryo assay (MEA) in order to improve sensitivity using clinical grade mineral oil with known peroxide concentrations...
January 7, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28032906/3-dimensional-functionalized-polycaprolactone-hyaluronic-acid-hydrogel-constructs-for-bone-tissue-engineering
#12
Stephen M Hamlet, Cedryck Vaquette, Amit Shah, Dietmar W Hutmacher, Saso Ivanovski
AIM: Alveolar bone regeneration remains a significant clinical challenge in periodontology and dental implantology. This study assessed the mineralized tissue forming potential of 3D printed medical grade polycaprolactone (mPCL) constructs containing osteoblasts encapsulated in a hyaluronic acid (HA) hydrogel incorporating bone morphogenetic protein-7 (BMP-7). MATERIALS AND METHODS: HA-hydrogels containing human osteoblasts ± BMP-7 were prepared. Cell viability, osteogenic gene expression, mineralized tissue formation and BMP-7 release in vitro, were assessed by fluorescence staining, RT-PCR, histological / μ-CT examination and ELISA respectively...
December 29, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28012008/bivariate-genome-wide-association-analyses-identified-genetic-pleiotropic-effects-for-bone-mineral-density-and-alcohol-drinking-in-caucasians
#13
Shan Lu, Lan-Juan Zhao, Xiang-Ding Chen, Christopher J Papasian, Ke-Hao Wu, Li-Jun Tan, Zhuo-Er Wang, Yu-Fang Pei, Qing Tian, Hong-Wen Deng
Several studies indicated bone mineral density (BMD) and alcohol intake might share common genetic factors. The study aimed to explore potential SNPs/genes related to both phenotypes in US Caucasians at the genome-wide level. A bivariate genome-wide association study (GWAS) was performed in 2069 unrelated participants. Regular drinking was graded as 1, 2, 3, 4, 5, or 6, representing drinking alcohol never, less than once, once or twice, three to six times, seven to ten times, or more than ten times per week respectively...
December 23, 2016: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/28000784/all-into-one-strategy-to-synthesize-mesoporous-hybrid-silicate-microspheres-from-naturally-rich-red-palygorskite-clay-as-high-efficient-adsorbents
#14
Wenbo Wang, Guangyan Tian, Dandan Wang, Zhifang Zhang, Yuru Kang, Li Zong, Aiqin Wang
A mesoporous hybrid silicate microsphere with superior adsorption performance has been successfully synthesized by employing an "all-into-one" strategy and a simple one-pot hydrothermal process using naturally abundant low-grade red palygorskite (PAL) clay as raw material in the presence of non-toxic SiO3(2-) and Mg(2+) ions. As is expected, both the PAL and associated minerals transformed into a new amorphous mesoporous hybrid silicate microsphere without using any additional pore-forming template. The mesoporous silicate microsphere shows a large pore size of 37...
December 21, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27983583/treated-seawater-as-a-magnesium-source-for-phosphorous-recovery-from-wastewater-a-feasibility-and-cost-analysis
#15
Cejna Anna Quist-Jensen, Mads Koustrup Jørgensen, Morten Lykkegaard Christensen
Conventional resources of phosphorous are at high risk of depletion in the near future due to current practices of its exploitation, thus new and improved exploration methodologies need to be developed to ensure phosphorous security. Today, some treatment plants recover phosphorous from municipal wastewater as struvite (MgNH₄PO₄·6H₂O). Magnesium is often added to the wastewater as MgCl₂·6H₂O to facilitate the phosphorous recovery. However, the use of magnesium increases the costs of the process and is not aligned with sustainable development, therefore, alternative magnesium sources have to be found...
December 13, 2016: Membranes
https://www.readbyqxmd.com/read/27966916/injectable-and-3d-bioprinted-polysaccharide-hydrogels-from-cartilage-to-osteochondral-tissue-engineering
#16
Janani Radhakrishnan, Anuradha Subramanian, Uma Maheswari Krishnan, Swaminathan Sethuraman
Biomechanical performance of functional cartilage is executed by the exclusive anisotropic composition and spatially varying intricate architecture in articulating ends of diarthrodial joint. Osteochondral tissue constituting the articulating ends comprise superfical soft cartilage over hard subchondral bone sandwiching interfacial soft-hard tissue. The shock-absorbent, lubricating property of cartilage and mechanical stability of subchondral bone regions are rendered by extended chemical structure of glycosaminoglycans and mineral deposition, respectively...
December 14, 2016: Biomacromolecules
https://www.readbyqxmd.com/read/27957294/adult-celiac-disease-patients-are-shorter-compared-with-their-peers-in-the-general-population
#17
Abbas Esmaeilzadeh, Azita Ganji, Ladan Goshayeshi, Kamran Ghafarzadegan, Mehdi Afzal Aghayee, Homan Mosanen Mozafari, Hassan Saadatniya, Abdolrasol Hayatbakhs, Vahid Ghavami Ghanbarabadi
BACKGROUND Delay in diagnosis of celiac disease (CD) occurs frequently, although its consequences are mostly not known. One of the presented symptoms in pediatric patients with CD is the short stature. However, far too little attention has been paid to physical features including height of adult patients with CD. This study was undertaken to evaluate whether patients suffering from CD are shorter in comparison with the general population without CD. As well, we evaluated probable correlations between demographic and physical features, main complains, serum anti tTG level, and intestinal pathology damage between short (lower quartile) versus tall stature (upper quartile) patients with CD...
October 2016: Middle East Journal of Digestive Diseases
https://www.readbyqxmd.com/read/27934285/in-situ-nanoscale-imaging-of-struvite-formation-during-the-dissolution-of-natural-brucite-implications-for-phosphorus-recovery-from-wastewaters
#18
Jörn Hövelmann, Christine V Putnis
As phosphorus (P) resources are diminishing, the recovery of this essential nutrient from wastewaters becomes an increasingly interesting option. P-recovery through the controlled crystallization of struvite (MgNH4PO4·6H2O), a potential slow-release fertilizer, is highly attractive, but costly if large amounts of Mg have to be added. In this context, natural Mg-minerals like brucite (Mg(OH)2) could provide more cost-effective Mg-sources compared to high-grade Mg-compounds such as MgCl2. Here we used in situ atomic force microscopy (AFM) to study the interactions of ammonium phosphate solutions with brucite (001) cleavage surfaces...
December 6, 2016: Environmental Science & Technology
https://www.readbyqxmd.com/read/27933738/exploratory-analysis-of-textual-data-from-the-mother-and-child-handbook-using-a-text-mining-method-ii-monthly-changes-in-the-words-recorded-by-mothers
#19
Miki Tagawa, Yoshio Matsuda, Tomoko Manaka, Makiko Kobayashi, Michitaka Ohwada, Shigeki Matsubara
AIM: The aim of the study was to examine the possibility of converting subjective textual data written in the free column space of the Mother and Child Handbook (MCH) into objective information using text mining and to compare any monthly changes in the words written by the mothers. METHODS: Pregnant women without complications (n = 60) were divided into two groups according to State-Trait Anxiety Inventory grade: low trait anxiety (group I, n = 39) and high trait anxiety (group II, n = 21)...
December 9, 2016: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/27930542/the-incidence-and-risk-factors-of-postoperative-neurological-deterioration-after-posterior-decompression-with-or-without-instrumented-fusion-for-thoracic-myelopathy
#20
Hui Wang, Lei Ma, Rui Xue, Dalong Yang, Tao Wang, Yanhong Wang, Sidong Yang, Wenyuan Ding
The aim of this study was to explore the incidence and risk factors of postoperative neurological deterioration after posterior decompression with or without instrumented fusion for thoracic myelopathy, and hope to provide references in decision-making and surgical planning for both spinal surgeon and thoracic stenosis patients.By retrieving the medical records from January 2001 to November 2015, 168 patients were retrospectively reviewed. According to the occurrence of postoperative neurological deterioration, patients were divided into 2 groups: neurological deterioration (ND) group and non-ND group...
December 2016: Medicine (Baltimore)
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