Francesco Pasqualetti, Michela Gabelloni, Lorenzo Faggioni, Giovanni Donato Aquaro, Fabrizio De Vietro, Vincenzo Mendola, Nicola Spina, Jessica Frey, Nicola Montemurro, Martina Cantarella, Mario Caccese, Giovanni Gadducci, Noemi Giannini, Silvia Valenti, Riccardo Morganti, Tamara Ius, Maria Caffo, Giuseppe Vergaro, Mirco Cosottini, Antonio Giuseppe Naccarato, Giuseppe Lombardi, Guido Bocci, Emanuele Neri, Fabiola Paiar
Purpose: Clinical evidence suggests an association between comorbidities and outcome in patients with glioblastoma (GBM). We hypothesised that the internal carotid artery (ICA) calcium score could represent a promising prognostic biomarker in a competing risk analysis in patients diagnosed with GBM. Methods: We validated the use of the ICA calcium score as a surrogate marker of the coronary calcium score in 32 patients with lung cancer. Subsequently, we assessed the impact of the ICA calcium score on overall survival in GBM patients treated with radio-chemotherapy...
March 6, 2024: Journal of Clinical Medicine