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Congenital syphilis

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https://www.readbyqxmd.com/read/29160448/availability-of-essential-medicines-in-primary-health-care-of-the-brazilian-unified-health-system
#1
Renata Cristina Rezende Macedo do Nascimento, Juliana Álvares, Augusto Afonso Guerra, Isabel Cristina Gomes, Ediná Alves Costa, Silvana Nair Leite, Karen Sarmento Costa, Orlando Mario Soeiro, Ione Aquemi Guibu, Margô Gomes de Oliveira Karnikowski, Francisco de Assis Acurcio
OBJECTIVE: To characterize the availability of tracer medicines in pharmaceutical services in primary health care of the Brazilian Unified Health System (SUS). METHODS: This is a cross-sectional and evaluative study, part of the Pesquisa Nacional Sobre Acesso, Utilização e Promoção do Uso Racional de Medicamentos - Serviços, 2015 (PNAUM - National Survey on Access, Use and Promotion of Rational Use of Medicines - Services, 2015). To analyze the availability of medicines, we verified 50 items selected from the Relação Nacional de Medicamentos Essenciais (Rename - National List of Essential Medicines) of 2012...
November 13, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/29102860/presence-of-dental-signs-of-congenital-syphilis-in-pre-modern-specimens
#2
REVIEW
Stella Ioannou, Renata J Henneberg, Maciej Henneberg
OBJECTIVE: Tooth morphology can vary due to genetic factors, infectious diseases and other environmental stresses. Congenital syphilis is known to interrupt tooth formation i.e. odontogenesis and amelogenesis, producing specific dental characteristics. Variation of those characteristics can occur, resulting in dental signs "not typical" of the disease, however, they are described in the 19th century literature. Past treatments of congenital syphilis with mercury also interrupted dental processes resulting in significantly different dental signs...
October 20, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29099873/assessing-zika-virus-replication-and-the-development-of-zika-specific-antibodies-after-a-mid-gestation-viral-challenge-in-guinea-pigs
#3
Craig J Bierle, Claudia Fernández-Alarcón, Nelmary Hernandez-Alvarado, Jason C Zabeli, Bradley C Janus, Dira S Putri, Mark R Schleiss
Primary Zika virus (ZIKV) infections that occur during pregnancy can cause spontaneous abortion and profoundly disrupt fetal development. While the full range of developmental abnormalities associated with congenital Zika syndrome is not yet known, severe cases of the syndrome can present with microcephaly, extensive neurologic and ocular damage, and pronounced joint malformations. Animal models that accurately recapitulate congenital Zika syndrome are urgently needed for vaccine development and for the study of ZIKV pathogenesis...
2017: PloS One
https://www.readbyqxmd.com/read/29027897/congenital-syphilis-in-england-and-amendments-to-the-bashh-guideline-for-management-of-affected-infants
#4
Margaret Kingston, Patrick French, Helen Fifer, Gwenda Hughes, Janet Wilson
No abstract text is available yet for this article.
November 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/29022569/syphilis
#5
REVIEW
Rosanna W Peeling, David Mabey, Mary L Kamb, Xiang-Sheng Chen, Justin D Radolf, Adele S Benzaken
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. T. pallidum is renowned for its invasiveness and immune-evasiveness; its clinical manifestations result from local inflammatory responses to replicating spirochaetes and often imitate those of other diseases. The spirochaete has a long latent period during which individuals have no signs or symptoms but can remain infectious. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries...
October 12, 2017: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/28983958/management-of-syphilis-in-pregnancy-knowledge-and-practices-of-health-care-providers-and-barriers-to-the-control-of-disease-in-teresina-brazil
#6
Danielle Carvalho Rodrigues, Rosa Maria Soares Madeira Domingues
AIMS: The aim of the study is to verify the knowledge and practices of health professionals working in prenatal care (PNC) related with syphilis during pregnancy and to identify the main barriers to the implementation of protocols for the control of this disease. METHODS: A cross-sectional study in Teresina, Brazil, from January to May 2015, was conducted with 366 physicians and nurses working in PNC, corresponding to 70% of eligible professionals. We evaluated 20 knowledge and practice criteria related to the diagnosis and treatment of syphilis during pregnancy with a 95% compliance standard...
October 6, 2017: International Journal of Health Planning and Management
https://www.readbyqxmd.com/read/28977175/underreporting-of-gestational-congenital-and-acquired-syphilis-among-indigenous-peoples-in-mato-grosso-do-sul-state-brazil-2011-2014
#7
Zuleica da Silva Tiago, Renata Palópoli Picoli, Samara Vilas-Boas Graeff, Rivaldo Venâncio da Cunha, Rui Arantes
OBJECTIVE: to describe the distribution, incidence, and underreporting of syphilis among indigenous peoples from Mato Grosso do Sul, Brazil. METHODS: descriptive study performed with secondary data of the Information System for Notifiable Diseases (Sinan) and of the Special Indigenous Sanitary District of Mato Grosso do Sul (DSEI-MS), from 2011 to 2014; the data from both sources were compared to identify underreporting. RESULTS: the highest incidence rates of syphilis in pregnant women were observed in 2014 (41...
July 2017: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
https://www.readbyqxmd.com/read/28977151/late-onset-congenital-syphilis-with-unusual-brain-abnormalities
#8
Rodrigo Alencar E Silva, Camila Campelo, Clecio Godeiro-Junior
No abstract text is available yet for this article.
September 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/28968019/-educating-health-workers-is-key-in-congenital-syphilis-elimination-in-colombia
#9
Juan Pablo Garcés, Luisa Consuelo Rubiano, Yenifer Orobio, Martha Castaño, Elizabeth Benavides, Adriana Cruz
INTRODUCTION: Colombia promotes the diagnosis and treatment of gestational syphilis in a single visit using rapid diagnostic tests to prevent mother-to-child transmission. Additionally, integrated health programs pursue the coordinated prevention of mother-to-child transmission of syphilis/HIV. OBJECTIVE: To identify knowledge gaps among health workers in the prevention of mother-to-child transmission of syphilis/HIV and to provide recommendations to support these programs...
September 1, 2017: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/28950764/unusual-presentation-of-secondary-syphilis-membranoproliferative-glomerulonephritis-andmuco-cutaneous-lesions
#10
Linda Tognetti, Elisa Cinotti, Sergio Tripodi, Guido Garosi, Pietro Rubegni
The worldwide re-emergence of secondary syphilis which happened in the last decade, has led to an increase in primary and secondary syphilis cases, along with the presentation of atypical forms. Nevertheless, reports of renal syphilis with mucosal and/or cutaneous manifestations are nowadays increasing. Typically, secondary syphilis infection in adults causes nephrotic syndrome due to a membranous glomerulonephritis. Here, we report a case of a 30-year-old immunocompetent man presenting with skin rash, oral and perianal erosions and nephritic syndrome...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28949262/monitoring-neonates-for-ototoxicity
#11
Angela C Garinis, Alison Kemph, Anne Marie Tharpe, Joern-Hendrik Weitkamp, Cynthia McEvoy, Peter S Steyger
OBJECTIVES: Neonates admitted to the neonatal intensive care unit (NICU) are at greater risk of permanent hearing loss compared to infants in well mother and baby units. Several factors have been associated with this increased prevalence of hearing loss, including congenital infections (e.g. cytomegalovirus or syphilis), ototoxic drugs (such as aminoglycoside or glycopeptide antibiotics), low birth weight, hypoxia and length of stay. The aetiology of this increased prevalence of hearing loss remains poorly understood...
June 22, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28942420/unique-manifestations-and-risk-factors-of-jarisch-herxheimer-reaction-during-treatment-of-child-congenital-syphilis
#12
Caiying Wang, Shuxin He, Hongling Yang, Yuhuan Liu, Yang Zhao, Lin Pang
OBJECTIVES: The objective of this retrospective study was to summarise the clinical manifestations of, and to analyse the incidence and risk factors of, Jarisch-Herxheimer reaction (JHR) during the treatment of children with symptomatic congenital syphilis. METHODS: Clinical data of 60 children with clinically and laboratory diagnosed congenital syphilis, hospitalised in Beijing Ditan Hospital between January 2010 and November 2015, were collected and analysed. RESULTS: A total of 11 patients with congenital syphilis (11/60, 18...
September 23, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28929534/emerging-arboviruses-in-rio-grande-do-sul-brazil-chikungunya-and-zika-outbreaks-2014-2016
#13
Tatiana Schäffer Gregianini, Tani Ranieri, Cátia Favreto, Zenaida Marion Alves Nunes, Gabriela Luchiari Tumioto Giannini, Nara Druck Sanberg, Marilda Tereza Mar da Rosa, Ana Beatriz Gorini da Veiga
QUESTIONS INVESTIGATED: The recent emergence of arboviruses such as Chikungunya virus (CHIKV) and Zika virus (ZIKV) in Brazil has posed a threat to human health and to the country's economy. Outbreaks occur mainly in tropical areas; however, increasing number of cases have been observed in Rio Grande do Sul (RS), the Southernmost state; therefore, surveillance of these arboviruses is essential for public health measures. DESIGN: In this study, we analyzed 1276 samples from patients with clinically suspected arboviral diseases between 2014 and 2016...
September 20, 2017: Reviews in Medical Virology
https://www.readbyqxmd.com/read/28923018/effects-on-preventing-mother-to-child-transmission-of-syphilis-and-associated-adverse-pregnant-outcomes-a-longitudinal-study-from-2001-to-2015-in-shanghai-china
#14
Yang Li, Liping Zhu, Li Du, Lingxiao Qu, Weili Jiang, Biao Xu
BACKGROUND: Maternal syphilis is a health threat to both the pregnant women and the children. This study aimed to delineate the longitudinal trend of maternal syphilis and burden of associated adverse pregnant outcomes (APOs) in Shanghai from 2001 to 2015; and to evaluate the effects of preventing mother-to-child transmission (PMTCT) of syphilis in Shanghai with regard to service coverage and APOs averted. METHODS: PMTCT program of syphilis has been implemented since 2001...
September 18, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28918883/pseudoparalysis-of-parrot-a-diagnostic-aid-in-congenital-syphilis
#15
Annelyse Araújo Pereira, Sandra Márcia Castro, Ranielly Ribeiro Venturini, Fernanda Oliveira César, Patricia Marques Fortes, Paulo Sucasas Costa
No abstract text is available yet for this article.
September 14, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28889773/sensitivity-of-npcr-for-four-types-of-membrane-protein-dna-and-of-two-pairs-of-primers-for-tpp47-dna-of-treponema-pallidum-in-whole-blood-of-congenital-syphilis-newborns
#16
Yafei Guan, Rong Ding, Yequn Zhou, Xiaoqin Chen, Xiaolin Miao, Ye Zhang, Dan Luo, Shudong Cui
BACKGROUND: Problems exist in congenital syphilis (CS) diagnosis and no single test can be used to diagnose CS. OBJECTIVE: To know whether there exist differences of nested polymerase chain reaction (nPCR) sensitivity among four membrane protein DNA and of nPCR between two pairs of primers for Tpp47. METHODS: We collected 30 CS patients as a study group, and 20 cases admitted to hospital for other reasons as a control group. The blood samples from newborns were left of blood for other examination, not special for the study...
September 22, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28876321/provider-adherence-to-syphilis-testing-recommendations-for-women-delivering-a-stillbirth
#17
Chirag G Patel, Jill S Huppert, Guoyu Tao
OBJECTIVE: To assess overall adherence to Centers for Disease Control and Prevention and American College of Obstetrics and Gynecology recommended guidelines for syphilis testing among women who delivered a stillbirth and compare it with other tests recommended for stillbirth evaluation. METHODS: We used MarketScan claims data with 40 million commercially insured and 8 million Medicaid enrollees annually to estimate prenatal care and follow-up testing among women who had stillbirths between January 1, 2013, and December 24, 2013...
November 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28845335/congenital-syphilis-masquerading-as-leukemia
#18
Tiffany Lee, Stephanie Bell, Jason Scimeme, Nizar Maraqa
As of late, the incidence of congenital syphilis in the United States is increasing. Each new case represents a failure of preventing, diagnosing, and treating syphilis in pregnant women. Pediatricians should confirm that all women have received adequate screening for and management of syphilis during pregnancy. Congenital syphilis is easily treatable but may be a diagnostic challenge with high morbidity and mortality.
July 2017: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/28837587/the-current-status-of-syphilis-prevention-and-control-in-jiangsu-province-china-a-cross-sectional-study
#19
Yuan-Fang Chen, Jian-Ping Ding, Hong-Jing Yan, Jing Lu, Ping Ding, Guo-Hong Chen, Jian-Jun Li, Xi-Ping Huan, Hai-Tao Yang, Wei-Ming Tang, Geng-Feng Fu
OBJECTIVE: To analyze the midterm evaluation data from the National Syphilis Prevention and Control Plan (2010-2020) and evaluate the current status of syphilis prevention and control in Jiangsu province, China. METHODS: We collected data via (1) field surveys conducted in 2015 and (2) data recorded in existing syphilis surveillance systems. We conducted descriptive statistical analysis to evaluate the current landscape of syphilis control initiatives and their potential effect in syphilis control...
2017: PloS One
https://www.readbyqxmd.com/read/28832755/assessment-in-the-primary-care-of-the-state-of-s%C3%A3-o-paulo-brazil-incipient-actions-in-sexual-and-reproductive-health
#20
Mariana Arantes Nasser, Maria Ines Battistella Nemes, Marta Campagnoni Andrade, Rogério Ruscitto do Prado, Elen Rose Lodeiro Castanheira
OBJECTIVE: The objective of this study is to assess performance in sexual and reproductive health of primary health care services of the Brazilian Unified Health System, in the State of São Paulo, Brazil. METHODS: An evaluative framework was built for sexual and reproductive health with the categorization of 99 indicators in three domains: sexual and reproductive health promotion (25), sexually transmitted infections/AIDS prevention and care (43), and reproductive health care (31)...
August 17, 2017: Revista de Saúde Pública
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