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Congenital syphilis

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https://www.readbyqxmd.com/read/28282647/suboptimal-prenatal-syphilis-testing-among-commercially-insured-women-in-the-united-states-2013
#1
Robyn Neblett Fanfair, Guoyu Tao, Kwame Owusu-Edusei, Thomas L Gift, Kyle T Bernstein
United States surveillance data demonstrate that congenital syphilis cases are increasing. We performed an analysis of commercially insured pregnant females using MarketSan to determine syphilis screening rates at different prenatal stages; 85% of pregnant women in this population had a syphilis test performed at least once during the prenatal period.
April 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28196316/common-skin-conditions-in-children-neonatal-skin-lesions
#2
Brian Z Rayala, Dean S Morrell
Skin findings during the initial month of life are ubiquitous. One study estimated that more than 95% of newborns have cutaneous findings, which often are distressing to parents but frequently are benign and self-limited. Among them are milia, cutis marmorata, congenital dermal melanocytosis, and the benign neonatal pustular eruptions (eg, benign cephalic pustulosis, erythema toxicum neonatorum, transient neonatal pustular melanosis). Clinicians need to recognize these benign skin conditions and differentiate them from more serious conditions, such as infectious pustular eruptions from bacterial, viral, and fungal causes, and inflammatory conditions, such as Langerhans cell histiocytosis...
February 2017: FP Essentials
https://www.readbyqxmd.com/read/28146181/educational-intervention-in-primary-care-for-the-prevention-of-congenital-syphilis
#3
Flaviane Mello Lazarini, Dulce Aparecida Barbosa
Objectives: to evaluate the efficiency of educational interventions related to the knowledge of health care professionals of Primary Care and to verify the impact on the vertical transmission rates of congenital syphilis. Method: a quasi-experimental study conducted in the city of Londrina, Paraná, between 2013 and 2015. An educational intervention on diagnosis, treatment and notification was carried out with 102 professionals with knowledge measurement before and after the intervention...
January 30, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/28146163/adherence-to-the-follow-up-of-the-newborn-exposed-to-syphilis-and-factors-associated-with-loss-to-follow-up
#4
Marjorie Cristiane Feliz, Adeli Regina Prizybicien, Andrea Maciel Rossoni, Tony Tahnus, Adriane Miro Vianna Benke Pereira, Cristina Rodrigues
Introduction: All newborns exposed to syphilis in pregnancy must have outpatient follow-up. The interruption of this follow-up especially threatens those children who were not treated at birth. Objective: To describe the clinical, epidemiological, and sociodemographic characteristics of pregnant women with syphilis and their newborns, and to investigate the factors associated with the discontinuation of the follow-up. Methods: This is an observational, descriptive, analytical, and retrospective study of medical records of 254 children exposed to syphilis, who were assisted at the Congenital Infectious Clinic of the university hospital of the Universidade Federal do Paraná, between 2000 and 2010...
October 2016: Revista Brasileira de Epidemiologia, Brazilian Journal of Epidemiology
https://www.readbyqxmd.com/read/28135431/retrospective-dual-center-study-of-parenteral-nutrition-associated-cholestasis-in-premature-neonates
#5
Weihui Yan, Li Hong, Ying Wang, Yi Feng, Lina Lu, Yijing Tao, Jiang Wu, Huijuan Ruan, Qingya Tang, Wei Cai
BACKGROUND: The pathogenesis of parenteral nutrition-associated cholestasis (PNAC) has not been clarified. The objective of this study was to explore the incidence of PNAC in premature infants without surgery and to identify associated risk factors. MATERIALS AND METHODS: Premature neonates who received parenteral nutrition (PN) at least 14 days were included in a retrospective, dual-center study. Cholestasis was diagnosed as conjugated bilirubin ≥2 mg/dL. Infants with metabolic liver disease, cyanotic congenital heart disease, congenital syphilis, hepadnaviridae infection, and those who underwent surgery were excluded...
January 1, 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/28120643/improving-the-antenatal-and-post-partum-management-of-women-presenting-to-sexual-health-services-with-positive-syphilis-serology-through-audit
#6
Christina H Munro, Ruth Henniker-Major, Virginia Homfray, Rita Browne
The incidence of congenital syphilis remains low in the UK, but the morbidity and mortality to babies born to women who are untreated for the condition make testing for the disease antenatally one of the most cost-effective screening programmes. Women attending North Middlesex Hospital, UK with a positive syphilis test at their antenatal booking visit are referred to St Ann's Sexual Health Clinic, London, for management and contact tracing. We were concerned that our initial audit revealed that a large proportion of women referred to our service never attended and recorded partner notification was poor...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28076583/-social-factors-associated-with-use-of-prenatal-care-in-ecuador
#7
Amaya Sánchez-Gómez, William Cevallos, Mario J Grijalva, Luis C Silva-Ayçaguer, Susana Tamayo, Jerry O Jacobson, Jaime A Costales, Rodrigo Jiménez-Garcia, Valentín Hernández-Barrera, Suzanne Serruya, Celia Riera
Objectives: Prenatal care is a pillar of public health, enabling access to interventions including prevention of mother-to-child transmission of HIV and congenital syphilis. This paper describes social factors related to use of prenatal care in Ecuador. Methods: In 2011 and 2012, participant clinical history and interview information was analyzed from a national probability sample of 5 998 women presenting for delivery or miscarriage services in 15 healthcare facilities in Ecuador, to estimate prevalence of HIV, syphilis, and Chagas disease, and prenatal care coverage...
November 2016: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/28029229/on-site-test-to-detect-syphilis-in-pregnancy-a-systematic-review-of-test-accuracy-studies
#8
REVIEW
E Rogozińska, L Kara-Newton, J R Zamora, K S Khan
BACKGROUND: Syphilis in pregnancy can lead to fetal and neonatal death or congenital anomalies. Accurate on-site tests are an essential part of effective prevention of mother-to-child transmission of the disease. OBJECTIVE: This systematic review assessed the accuracy of on-site tests to detect infection with Treponema pallidum in pregnant women. SEARCH STRATEGY: Major databases were searched from inception to January 2016 using terms: 'pregnancy', 'antenatal', 'syphilis', 'Treponema pallidum' with their variations, and the search limit for the relevant study design...
December 28, 2016: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27977652/auckland-city-of-syphilis
#9
Sunita Azariah
AIMS: To briefly report on the large increase in cases of syphilis managed at Auckland Regional Sexual Health Service (ARSHS) in 2015. To raise awareness of syphilis as an emerging significant public health issue in Auckland. METHOD: A search was conducted of the electronic patient management system at ARSHS for cases of syphilis diagnosed between 1st of January 2015 and 31st of December 2015. Those that fitted the Institute of Environmental Science and Research Ltd (ESR) case definitions for infectious syphilis were included and demographic, clinical and behavioural characteristics were described...
December 16, 2016: New Zealand Medical Journal
https://www.readbyqxmd.com/read/27956203/syphilis-during-pregnancy-a-preventable-threat-to-maternal-fetal-health
#10
REVIEW
Martha W F Rac, Paula A Revell, Catherine S Eppes
Syphilis remains the most common congenital infection worldwide and has tremendous consequences for the mother and her developing fetus if left untreated. Recently, there has been an increase in the number of congenital syphilis cases in the United States. Thus, recognition and appropriate treatment of reproductive-age women must be a priority. Testing should be performed at initiation of prenatal care and twice during the third trimester in high-risk patients. There are 2 diagnostic algorithms available and physicians should be aware of which algorithm is utilized by their testing laboratory...
December 9, 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27941983/underreporting-of-congenital-syphilis-as-a-cause-of-fetal-and-infant-deaths-in-northeastern-brazil
#11
Ana Rita Paulo Cardoso, Maria Alix Leite Araújo, Roumayne Fernandes Vieira Andrade, Valéria Saraceni, Angelica E Miranda, Maria Inês Costa Dourado
INTRODUCTION: Of all syphilis-related pregnancy outcomes, fetal death is certainly the most common one, being directly related to the availability, accessibility and quality of prenatal care. The present study aimed to analyze the underreporting of fetal and infant deaths and other maternal factors associated with congenital syphilis (CS) death. METHODS: This cross-sectional study integrated data of infants that were diagnosed and/or died of CS from the Sistema de Informação de Agravos de Notificação-Sinan (Notifiable Diseases Information System) and the Sistema de Informação de Mortalidade-SIM (Mortality Information System) in Fortaleza, Northeastern Brasil to identify unreported cases of congenital syphilis...
2016: PloS One
https://www.readbyqxmd.com/read/27835624/cuba-validated-as-the-first-country-to-eliminate-mother-to-child-transmission-of-human-immunodeficiency-virus-and-congenital-syphilis-lessons-learned-from-the-implementation-of-the-global-validation-methodology
#12
Sonja Caffe, Freddy Perez, Mary L Kamb, Rodolfo Gomez Ponce de Leon, Monica Alonso, Ralph Midy, Lori Newman, Chika Hayashi, Massimo Ghidinelli
No abstract text is available yet for this article.
December 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27810981/maternal-syphilis-and-accomplishing-sexual-partner-treatment-still-a-huge-gap
#13
Jessica Dallé, Vanessa Z Baumgarten, Mauro C Ramos, Mirela F Jimenez, Lisiane Acosta, Daniela B Bumaguin, Vicente S Antonello
Congenital syphilis (CS) is a preventable epidemic disease for which control is hindered by socioeconomic and health system issues. Inadequately treated maternal syphilis (MaS) commonly has serious adverse obstetric outcomes. This study - which is a cross-sectional study in a Brazilian large urban public Mother and Child hospital, making use of secondary data - evaluated the occurrence of treatment of sexual partners (SP) among women with MaS. The results showed that 771 MaS cases were identified from 2007 to 2014...
November 2, 2016: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/27774886/the-clinico-hematological-features-and-management-outcome-in-neonatal-malaria-a-nine-years-analysis-from-north-india
#14
Kriti Mohan
BACKGROUND: Malaria is an important cause of death and illness in children worldwide. Most cases of neonatal malaria are misdiagnosed because of the lack of specific symptoms and a general lack of awareness. Nothing much is known in literature about the haematological changes during malaria infection and outcome of disease in neonates. Neonatal malaria is an underdiagnosed entity. So this hospital based observational study aims to assess diagnostic features of neonatal malaria. METHODS: From August 2004 to August 2013, information of all slide positive for malaria cases aged 0 to 28 days admitted to our pediatric hospital was collected and analysed...
October 20, 2016: Infectious Disorders Drug Targets
https://www.readbyqxmd.com/read/27763844/examination-of-a-prenatal-syphilis-screening-program-alberta-canada-2010-2011
#15
Sabrina S Plitt, Mariam Osman, Vanita Sahni, Bonita E Lee, Carmen Charlton, Kimberley Simmonds
OBJECTIVES: In 2009, due to increasing congenital syphilis rates, prenatal syphilis tests (PST) at both mid-gestation and delivery were added to first trimester prenatal screening in the province of Alberta. We sought to determine the proportion of mothers who had all three recommended PSTs during this period and to identify factors associated with incomplete PST. METHODS: A cohort of all pregnancies resulting in a live or stillborn infant in Alberta for 2010 and 2011 was developed from Vital Statistics and linked with prenatal screening data to determine the number and timing of PSTs for pregnant women...
October 20, 2016: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/27756083/syphilis-in-pregnancy-and-congenital-syphilis-why-can-we-not-yet-face-this-problem
#16
Helaine Milanez
No abstract text is available yet for this article.
September 2016: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/27715301/the-cuban-experience-in-the-elimination-of-mother-to-child-transmission-of-congenital-syphilis
#17
Islay Rodríguez, Angel A Noda, Katia Ale, Lola V Stamm
No abstract text is available yet for this article.
November 2016: American Journal of Public Health
https://www.readbyqxmd.com/read/27711044/evaluation-of-the-management-of-pregnancies-and-infants-at-risk-for-congenital-syphilis-la-r%C3%A3-union-2008-to-2014
#18
M Le Chevalier de Préville, J-L Alessandri, N Traversier, F Cuillier, S Robin, D Ramful
OBJECTIVE: To evaluate the maternal-fetal management and follow-up of infants at risk for congenital syphilis. STUDY DESIGN: Monocentric retrospective cohort study at the Félix Guyon Hospital, Saint-Denis, La Réunion between January 2008 and December 2014. Management of 38 pregnancies (35 women, 39 fetuses) with a positive syphilis serology was evaluated according to the Centers for Disease Control and Prevention (CDC) guidelines. RESULTS: A total of 68% (n=26) of pregnancies were screened before 16 weeks of gestation, and 26% (n=10) had appropriate treatment...
October 6, 2016: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/27699849/bilateral-congenital-coronary-ostial-obstruction-exertional-syncope-in-an-otherwise-healthy-8-year-old
#19
Kavita Sharma, Poonam Thankavel
Congenital stenosis/atresia of a coronary artery is an exquisitely rare anomaly (Congenit Heart Dis, 2, 2007, 347) with increased risk of sudden death. Bilateral coronary obstruction is even more unusual but has been reported in conjunction with aortic valve disease, syphilis, and Takayasu's arteritis. To the best of our knowledge, obstruction of both coronaries in a pediatric patient has only been reported once (Ann Thorac Surg, 55, 1993, 1564). We present a patient with an intramural, anomalous aortic origin of the right coronary artery from the contralateral sinus (AAORCA) with near atresia of the left main coronary ostium...
December 2016: Echocardiography
https://www.readbyqxmd.com/read/27644020/progressive-lesions-of-central-nervous-system-in-microcephalic-fetuses-with-suspected-congenital-zika-virus-syndrome
#20
Manoel Sarno, Marcelo Aquino, Kleber Pimentel, Renata Cabral, Gisela Costa, Fernanda Bastos, Carlos Brites
OBJECTIVE: Our aim was to describe the pattern and progression of Central Nervous System (CNS) lesions of microcephalic fetuses with suspected Zika Virus (ZIKV) infection. METHODS: We analyzed fetuses diagnosed with microcephaly after a routine primary care ultrasound scan suspect a fetal microcephaly in Salvador, Brazil, from July/2015 to February/2016 and these pregnancies were followed until delivery. Microcephaly was diagnosed when the head circumference was below two or more standard deviation for gestational age and its relationship with ZIKV infection was defined according to World Health Organization criteria...
September 19, 2016: Ultrasound in Obstetrics & Gynecology
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