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Geriatric AND cancer

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https://www.readbyqxmd.com/read/29348384/clinical-outcomes-of-geriatric-care-in-cipto-mangunkusumo-hospital-before-and-after-the-implementation-of-national-health-insurance-program
#1
Czeresna Heriawan Soejono, Retna S Padmawati, Adi Utarini
BACKGROUND: the National Health Insurance (NIH/JKN) has been enacted since January 2014. Various outcomes of geriatric patient care, such as improved functional status and quality of life have not been evaluated. Prolonged hospitalization and re-hospitalization are potentially affecting the efficiency care of this vulnarable group. This study aimed to identify the differences of functional status improvement, quality of life improvement, length of stay, and hospitalization of geriatric patients admitted to CMH between prior to and after NHI implementation...
October 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/29341337/endoscopic-endonasal-approach-for-sinonasal-and-anterior-skull-base-malignancies-in-the-elderly
#2
Davide Lepera, Federico Leone, Luca Volpi, Maurizio Bignami, Apostolos Karligkiotis, Alessia Lambertoni, Andrea Pistochini, Remo Accorona, Piero Nicolai, Paolo Castelnuovo
BACKGROUND: The purpose of this study was to report the outcomes of endoscopic transnasal resection for sinonasal and anterior skull-base cancers in elderly patients. METHODS: A retrospective review was performed. The patients were divided into 2 groups, <70 years old and ≥70 years old and compared by univariate analysis. Prognostic factors were evaluated with a multivariate analysis. Survival rates were also calculated. RESULTS: Two hundred three elderly patients and 397 younger patients were enrolled in this study...
January 17, 2018: Head & Neck
https://www.readbyqxmd.com/read/29338688/transurethral-resection-of-the-prostate-provides-more-favorable-clinical-outcomes-compared-with-conservative-medical-treatment-in-patients-with-urinary-retention-caused-by-benign-prostatic-obstruction
#3
Yu-Hsiang Lin, Chen-Pang Hou, Tien-Hsing Chen, Horng-Heng Juang, Phei-Lang Chang, Pei-Shan Yang, Chien-Lun Chen, Ke-Hung Tsui
BACKGROUND: To evaluate the long-term surgical outcomes of patients with urinary retention (UR) caused by a benign prostatic obstruction (BPO) who underwent transurethral resection of the prostate (TURP), and compare their outcomes with those of patients who received medication without surgical intervention. METHODS: This retrospective cohort study analyzed claims data collected during the period of 1997-2012 from Taiwan's National Health Insurance Research Database...
January 16, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29335033/should-capacity-assessments-be-performed-routinely-prior-to-discussing-advance-care-planning-with-older-people
#4
Oleg Kiriaev, Emme Chacko, J D Jurgens, Meagan Ramages, Phillipa Malpas, Gary Cheung
BACKGROUND: People with dementia receive worse end of life care compared to those with cancer. Barriers to undertaking advanced care planning (ACP) in people with dementia include the uncertainty about their capacity to engage in such discussions. The primary aim of this study was to compare the Advance Care Planning-Capacity Assessment Vignette tool (ACP-CAV) with a semi-structured interview adapted from the MacArthur Competence Assessment Tool-Treatment (MacCAT-T). The secondary aim was to identify demographic and cognitive functioning variables that may predict whether a person has capacity to discuss ACP...
January 16, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/29333024/a-risk-benefit-assessment-approach-to-selection-of-adjuvant-chemotherapy-in-elderly-patients-with-early-breast-cancer-a-mini-review
#5
REVIEW
Vivek Agarwala, Neha Choudhary, Sudeep Gupta
Decision-making regarding the use and selection of adjuvant chemotherapy for breast cancer in elderly patients is challenging due to the presence of age-related comorbidities, frailty, and competing causes of mortality. One area, relatively neglected in most guidelines, is the effect of competing causes of mortality on presumed benefit of adjuvant chemotherapy for breast cancer in these patients. This article utilizes a clinical case to illustrate the principles of risk-benefit assessment of adjuvant chemotherapy in elderly patients...
October 2017: Indian Journal of Medical and Paediatric Oncology
https://www.readbyqxmd.com/read/29331624/comprehensive-geriatric-assessment-in-the-older-adult-with-cancer-a-review
#6
REVIEW
Catalina Hernandez Torres, Tina Hsu
CONTEXT: The number of older adults with cancer is expected to increase rapidly in the upcoming decades. Aging is heterogeneous and chronological age is often not reflective of biological age. A comprehensive geriatric assessment (CGA) is an in-depth assessment of multiple domains of health that results in better assessment of a patient's overall health and fitness and allows directed intervention to improve patient outcomes. OBJECTIVE: To review the value of CGA for older adults with cancer, CGA composition and tools that can be utilized, and the feasibility of including CGA in oncologic practice...
January 10, 2018: European Urology Focus
https://www.readbyqxmd.com/read/29327240/geriatric-oncology-in-spain-survey-results-and-analysis-of-the-current-situation
#7
R Gironés, I Morilla, C Guillen-Ponce, M D Torregrosa, I Paredero, E Bustamante, S Del Barco, G Soler, B Losada, L Visa, E Llabrés, B Fox, J L Firvida, R Blanco, M Antonio, F Aparisi, M Pi-Figueras, E Gonzalez-Flores, M J Molina-Garrido, J Saldaña
INTRODUCTION: Geriatric oncology (GO) is a discipline that focuses on the management of elderly patients with cancer. The Spanish Society of Medical Oncology (SEOM) created a Working group dedicated to geriatric oncology in February 2016. OBJECTIVES: The main goal of this study was to describe the current situation in Spain regarding the management of elderly cancer patients through an online survey of medical oncologists. METHODS: A descriptive survey was sent to several hospitals by means of the SEOM website...
December 11, 2017: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/29302544/morbidity-pattern-and-its-sociodemographic-determinants-among-elderly-population-of-raichur-district-karnataka-india
#8
Leyanna Susan George, Sanjay Deshpande, M K Krishna Kumar, Ramesh S Patil
Context: India is an "aging nation" with 7.7% of its population being above 60 years of age. It has resulted in a rise of both physical and mental health morbidities. Aims: This study aimed to gather information regarding the morbidity pattern and its sociodemographic determinants among the elderly residing in the rural villages of Raichur, to understand the need for geriatric health-care facilities. Settings and Design: This community-based cross-sectional study was carried out in six rural villages of Raichur District, of which 230 elderly were selected randomly...
April 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29299751/risk-factors-for-unplanned-discontinuation-of-scheduled-treatment-in-elderly-patients-with-castration-resistant-prostate-cancer-results-of-the-ibutu-study
#9
Friedemann Honecker, Ulrich Wedding, Gerd Kallischnigg, Axel Schroeder, Jörg Klier, Thomas Frangenheim, Lothar Weißbach
PURPOSE: To gain knowledge about the factors associated with discontinuation of scheduled treatment in elderly men with castration-resistant prostate cancer (CRPC). METHODS: Patients ≥ 70 years with CRPC starting a new line of treatment were included in a prospective cohort study. A geriatric assessment (CGA) was performed at baseline, including comorbidity, mobility, functional/mental/nutritional status, as well as depression. Furthermore, pain intensity, quality of life, ECOG-performance status, and physicians' and patients' perception of health were documented...
January 4, 2018: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/29285042/treatment-patterns-and-outcomes-in-elderly-patients-with-metastatic-breast-cancer-a-multicenter-retrospective-study
#10
Jin Hyun Park, In Sil Choi, Ki Hwan Kim, Jin-Soo Kim, Kyung-Hun Lee, Tae-Yong Kim, Seock-Ah Im, Se Hyun Kim, Yu Jung Kim, Jee Hyun Kim
Purpose: Currently, there is little information regarding optimal treatment for metastatic breast cancer (MBC) in elderly patients. In this retrospective study, we examined a cohort of elderly patients with MBC receiving a range of treatments, in terms of demographic and clinicopathologic characteristics, treatment patterns, and outcomes. Methods: Patients aged 65 years and older, and diagnosed with MBC between 2003 and 2015, were identified from the databases of three academic hospitals in South Korea...
December 2017: Journal of Breast Cancer
https://www.readbyqxmd.com/read/29250775/most-impactful-factors-on-the-health-related-quality-of-life-of-a-geriatric-population-with-cancer
#11
Maria Pisu, Andres Azuero, Karina I Halilova, Courtney P Williams, Kelly M Kenzik, Elizabeth A Kvale, Grant R Williams, Karen Meneses, Margaret Sullivan, Supriya Kumar Yagnik, Hans-Peter Goertz, Gabrielle B Rocque
BACKGROUND: As the population of older adults with cancer continues to grow, the most important factors contributing to their health-related quality of life (HRQOL) remain unclear. METHODS: A total of 1457 older adults (aged ≥65 years) with cancer participated in a telephone survey. Outcomes were measured using the Physical Component Summary (PCS) and Mental Component Summary (MCS) scores of the 12-Item Short Form Survey (SF-12) from the Medical Outcomes Study (version 2)...
December 18, 2017: Cancer
https://www.readbyqxmd.com/read/29248435/delphi-consensus-of-an-expert-committee-in-oncogeriatrics-regarding-comprehensive-geriatric-assessment-in-seniors-with-cancer-in-spain
#12
Maria-Jose Molina-Garrido, Carmen Guillén-Ponce, Remei Blanco, Juana Saldaña, Jaime Feliú, Maite Antonio, Rosa López-Mongil, Primitivo Ramos Cordero, Regina Gironés
OBJECTIVES: The aim of this work was to reach a national consensus in Spain regarding the Comprehensive Geriatric Assessment (CGA) domains in older oncological patients and the CGA scales to be used as a foundation for widespread use. MATERIAL AND METHODS: The Delphi method was implemented to attain consensus. Representatives of the panel were chosen from among the members of the Oncogeriatric Working Group of the Spanish Society of Medical Oncology (SEOM). Consensus was defined as ≥66...
December 13, 2017: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/29247754/advance-care-planning-in-community-dwelling-patients-with-dementia
#13
Jane L Givens, Rebecca L Sudore, Gad A Marshall, Alyssa B Dufour, Ilona Kopits, Susan L Mitchell
CONTEXT: Little is known about advance care planning (ACP) among community-dwelling patients with dementia. OBJECTIVES: To describe aspects of ACP among patients with dementia and examine the association between ACP and health care proxy (HCP) acceptance of patient illness. METHODS: Cross sectional observational survey of 62 HCPs of patients with dementia (N=14 mild, N=48 moderate/severe), from 7 outpatient geriatric and memory disorder clinics in Boston...
December 13, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/29243107/impact-of-geriatric-assessment-for-the-therapeutic-decision-making-of-breast-cancer-results-of-a-french-survey-afsos-and-sofog-collaborative-work
#14
Claire Falandry, Ivan Krakowski, Hervé Curé, Elisabeth Carola, Pierre Soubeyran, Olivier Guérin, Hélène Gaudin, Gilles Freyer
BACKGROUND: Cancer management in the elderly is often considered as suboptimal, highly variable, and rarely evidence-based. Data are needed to understand decision-making processes in this population. MATERIALS AND METHODS: A survey was performed in France to describe decision-making in gynaecologic patients over 70. It followed a three-step method: (1) 101 representative physicians questioned about treatment decision criteria; (2) simplified individual data were collected; (3) as well as detailed data patients receiving chemotherapy...
December 14, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29242282/patient-reported-comorbidity-and-survival-in-older-adults-with-cancer
#15
Grant R Williams, Allison M Deal, Jennifer L Lund, YunKyung Chang, Hyman B Muss, Mackenzi Pergolotti, Emily J Guerard, Shlomit Strulov Shachar, Yue Wang, Kelly Kenzik, Hanna K Sanoff
BACKGROUND: Our ability to optimize the care of older adults with cancer and comorbid illnesses is insufficient because most clinical trials lack systematic measurement. The primary purpose of this study was to evaluate the association between patient-reported comorbidity and all-cause mortality using various comorbidity scoring algorithms. MATERIALS AND METHODS: The Carolina Senior Registry was linked with the North Carolina Central Cancer Registry to obtain mortality data...
December 14, 2017: Oncologist
https://www.readbyqxmd.com/read/29240884/a-proposal-for-a-comprehensive-risk-scoring-system-for-predicting-postoperative-complications-in-octogenarian-patients-with-medically-operable-lung-cancer-jacs1303
#16
Hisashi Saji, Takahiko Ueno, Hiroshige Nakamura, Norihito Okumura, Masanori Tsuchida, Makoto Sonobe, Takuro Miyazaki, Keiju Aokage, Masayuki Nakao, Tomohiro Haruki, Hiroyuki Ito, Kazuhiko Kataoka, Kazunori Okabe, Kenji Tomizawa, Kentaro Yoshimoto, Hirotoshi Horio, Kenji Sugio, Yasuhisa Ode, Motoshi Takao, Morihito Okada, Masayuki Chida
OBJECTIVES: Although some retrospective studies have reported clinicopathological scoring systems for predicting postoperative complications and survival outcomes for elderly lung cancer patients, optimized scoring systems remain controversial. METHODS: The Japanese Association for Chest Surgery (JACS) conducted a nationwide multicentre prospective cohort and enrolled a total of 1019 octogenarians with medically operable lung cancer. Details of the clinical factors, comorbidities and comprehensive geriatric assessment were recorded for 895 patients to develop a comprehensive risk scoring (RS) system capable of predicting severe complications...
December 11, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29238654/primary-endocrine-therapy-in-older-women-with-breast-cancer
#17
REVIEW
R M C Pepping, J E A Portielje, W van de Water, N A de Glas
Purpose of Review: Breast cancer incidence increases with age. In recent years, primary endocrine therapy has been increasingly used as a treatment option for frail elderly women with breast cancer, although surgery is still the guideline-recommended treatment. In this review, we discuss the evidence for primary endocrine therapy versus surgical treatment in older women with early breast cancer. Recent Findings: Both randomised controlled trials and recent observational studies showed a favourable progression-free survival but not overall survival for surgery plus adjuvant endocrine therapy versus primary endocrine therapy...
2017: Current Geriatrics Reports
https://www.readbyqxmd.com/read/29237969/agreement-analysis-between-three-different-short-geriatric-screening-scales-in-patients-undergoing-chemotherapy-for-solid-tumors
#18
Amit Joshi, Nidhi Tandon, Vijay M Patil, Vanita Noronha, Sudeep Gupta, Atanu Bhattacharjee, Kumar Prabhash
BACKGROUND: Comprehensive geriatric assessment (CGA) in routine practice is not logistically feasible. Short geriatric screening tools are available for selecting patients for CGA. However none of them is validated in India. In this analysis we aim to compare the level of agreement between three commonly used short screening tools (Flemish version of TRST (fTRST), G8 and VES-13. METHODS: Patients ≥65 years with a solid tumor malignancy undergoing cancer directed treatment were interviewed between March 2013 to July 2014...
October 2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29237919/efficacy-and-safety-of-bevacizumab-in-elderly-patients-with-advanced-colorectal-cancer-a-meta-analysis
#19
Xiuxing Chen, Yanfeng Chen, Xiuyu Cai, Dongsheng Zhang, Lei Fan, Huijuan Qiu, Bei Zhang, Guifang Guo
AIMS: Bevacizumab plus chemotherapy (CT) has been the standard treatment for advanced colorectal cancer (ACRC) in the last decade. However, whether geriatric patients treated with this combination achieved more benefits or suffered severer toxicities than CT alone remained controversial. This meta-analysis was aimed to provide more convincing evidence. SUBJECTS AND METHODS: Randomized control trials (RCTs) and retrospective comparative studies on the comparison between bevacizumab plus CT and CT for geriatric ACRC patients were retrieved in PubMed, Web of Science, EMBASE, and Ovid until June 2016...
2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29212610/moving-beyond-symptom-management-towards-cancer-rehabilitation-for-older-adults-answering-the-5w-s
#20
REVIEW
Mackenzi Pergolotti, Kathleen D Lyons, Grant R Williams
Older adults with cancer are quickly becoming the largest group of cancer survivors. Chronological age is a poor predictor of cancer treatment outcomes and of the need for rehabilitation services. While newer symptom management systems and assessments are slowly becoming used in the clinic to improve communication between providers and survivors, such assessments are rarely used to trigger a referral to rehabilitation. Cancer rehabilitation for older adults with cancer has the potential to improve the quality of life and decrease disability caused by cancer and its treatments...
December 3, 2017: Journal of Geriatric Oncology
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