keyword
MENU ▼
Read by QxMD icon Read
search

Geriatric AND cancer

keyword
https://www.readbyqxmd.com/read/28526493/improving-comfort-around-dying-in-elderly-people-a-cluster-randomised-controlled-trial
#1
Kim Beernaert, Tinne Smets, Joachim Cohen, Rebecca Verhofstede, Massimo Costantini, Kim Eecloo, Nele Van Den Noortgate, Luc Deliens
BACKGROUND: Over 50% of elderly people die in acute hospital settings, where the quality of end-of-life care is often suboptimum. We aimed to assess the effectiveness of the Care Programme for the Last Days of Life (CAREFuL) at improving comfort and quality of care in the dying phase in elderly people. METHODS: We did a cluster randomised controlled trial in acute geriatric wards in ten hospitals in Flemish Region, Belgium, between Oct 1, 2012, and March 31, 2015...
May 16, 2017: Lancet
https://www.readbyqxmd.com/read/28501109/sarcopenia-a-new-predictor-of-postoperative-complications-for-elderly-gastric-cancer-patients-who-underwent-radical-gastrectomy
#2
Chong-Jun Zhou, Feng-Min Zhang, Fei-Yu Zhang, Zhen Yu, Xiao-Lei Chen, Xian Shen, Cheng-Le Zhuang, Xiao-Xi Chen
BACKGROUND: A geriatric assessment is needed to identify high-risk elderly patients with gastric cancer. However, the current geriatric assessment has been considered to be either time-consuming or subjective. The present study aimed to investigate the predictive effect of sarcopenia on the postoperative complications for elderly patients who underwent radical gastrectomy. MATERIALS AND METHODS: We conducted a prospective study of patients who underwent radical gastrectomy from August 2014 to December 2015...
May 1, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28499724/cardio-oncology-in-the-older-adult
#3
REVIEW
Prajwal Reddy, Chetan Shenoy, Anne H Blaes
Heart disease and cancer are the leading causes of death in older adults. Many first-line cancer treatments have the potential for cardiotoxicity. Age-related risk factors, pre-existing cardiac disease, and a high prevalence of comorbidities are reasons for increased cardiotoxicity in older adults. Concerns regarding cardiotoxicity may lead to frailty bias and undertreatment, resulting in suboptimal outcomes. There is an urgent need for geriatric-specific evidence and guidelines to help tailor care for this vulnerable group...
May 9, 2017: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/28498197/overuse-of-health-care-services-in-the-management-of-cancer-a-systematic-review
#4
Shrujal S Baxi, Minal Kale, Salomeh Keyhani, Benjamin R Roman, Annie Yang, Antonio P Derosa, Deborah Korenstein
BACKGROUND: Overuse, the provision of health services for which harms outweigh the benefits, results in suboptimal patient care and may contribute to the rising costs of cancer care. We performed a systematic review of the evidence on overuse in oncology. METHODS: We searched Medline, EMBASE, the Cochrane Library, Web of Science, SCOPUS databases, and 2 grey literature sources, for articles published between December 1, 2011 and March 10, 2017. We included publications from December 2011 to evaluate the literature since the inception of the ABIM Foundation's Choosing Wisely initiative in 2012...
May 11, 2017: Medical Care
https://www.readbyqxmd.com/read/28493841/diagnostic-performance-of-gait-speed-g8-and-g8-modified-indices-to-screen-for-vulnerability-in-older-cancer-patients-the-prospective-pf-ec-cohort-study
#5
Frederic Pamoukdjian, Florence Canoui-Poitrine, Coralie Longelin-Lombard, Thomas Aparicio, Nathalie Ganne, Philippe Wind, Claudia Martinez-Tapia, Etienne Audureau, Georges Sebbane, Laurent Zelek, Elena Paillaud
BACKGROUND: The diagnostic performance of tools used to screen vulnerability in older cancer patients varies widely. We assessed the diagnostic performance of gait speed (GS) for assessing vulnerability in such patients. METHODS: All consecutive outpatients 65 years and older were referred for geriatric oncology assessment (GA) before a therapeutic decision between November 2013 and April 2016 in a bicentric observational and prospective cohort study. Vulnerability was defined as impaired score on at least one of the 6 domains of the GA...
April 21, 2017: Oncotarget
https://www.readbyqxmd.com/read/28488143/methodology-of-phase-ii-clinical-trials-in-metastatic-elderly-breast-cancer-a-literature-review
#6
REVIEW
B Cabarrou, L Mourey, F Dalenc, L Balardy, D Kanoun, H Roché, J M Boher, M E Rougé-Bugat, Thomas Filleron
PURPOSE: As the incidence of invasive breast cancer will increase with age, the number of elderly patients with a diagnosis metastatic breast cancer will also rise. But the use of cytotoxic drugs in elderly metastatic breast cancer patients is not systematic and is dreaded by medical oncologists. The need for prospective oncologic data from this population seems increasingly obvious. The main objective of this review is to investigate design and characteristics of phase II trials that assess activity and feasibility of chemotherapies in elderly advanced/metastatic breast cancer patients...
May 9, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28487749/highlights-from-the-first-ecancer-liga-colombiana-contra-el-cancer-conference-17-18-november-2016-bogota-colombia
#7
Carlos Castro
The first oncology conference organised by ecancer and the Liga Colombiana contra el Cancer took place on 17-18 November 2016 in Bogota. It was a highly successful event owing to the number of participants, the quality of the speakers, and the academic programme. Around 48 professors from 8 different countries came and shared their knowledge and experience of cancer management. They also talked about the most recent developments noted or achieved in this area. The keynote speech from Dr Nubia Muñoz was of great interest which was related to the safety of a HPV vaccine and the implications of a mass vaccination programme in developing countries...
2017: Ecancermedicalscience
https://www.readbyqxmd.com/read/28487465/geriatric-assessment-predicts-survival-and-competing-mortality-in-elderly-patients-with-early-colorectal-cancer-can-it-help-in-adjuvant-therapy-decision-making
#8
Maite Antonio, Juana Saldaña, Alberto Carmona-Bayonas, Valentín Navarro, Cristian Tebé, Marga Nadal, Francesc Formiga, Ramon Salazar, Josep Maria Borràs
BACKGROUND: The challenge when selecting elderly patients with colorectal cancer (CRC) for adjuvant therapy is to estimate the likelihood that death from other causes will preclude cancer events from occurring. The aim of this paper is to evaluate whether comprehensive geriatric assessment (CGA) can predict survival and cancer-specific mortality in elderly CRC patients candidates for adjuvant therapy. MATERIAL AND METHODS: One hundred ninety-five consecutive patients aged ≥75 with high-risk stage II and stage III CRC were prospectively included from May 2008 to May 2015...
May 9, 2017: Oncologist
https://www.readbyqxmd.com/read/28464424/impact-of-long-hours-family-caregiving-on-non-fatal-coronary-heart-disease-risk-in-middle-aged-people-results-from-a-longitudinal-nationwide-survey-in-japan
#9
Atsushi Miyawaki, Jun Tomio, Yasuki Kobayashi, Hideto Takahashi, Haruko Noguchi, Nanako Tamiya
AIM: The effects of family caregiving, especially long-hours caregiving, on coronary heart disease (CHD) are debatable. We examined the impact of family caregiving on incident non-fatal CHD. METHODS: We used data from the Longitudinal Survey of Middle-Aged and Elderly Persons from 2005 to 2010, a nationwide panel survey for Japanese people aged 50-59 years in 2005 (baseline). After we excluded non-respondents and people with missing key variables at baseline, 25 121 individuals without CHD, stroke or cancer were followed up for a mean of 4...
May 2, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/28458958/the-intersection-of-oncology-prognosis-and-cancer-rehabilitation
#10
REVIEW
Sean Robinson Smith, Jasmine Yiqian Zheng
PURPOSE OF REVIEW: This review examines the delivery of rehabilitation care to cancer patients with relation to disease prognosis. This includes the evaluation when patients are referred for rehabilitation services and the effectiveness of rehabilitation interventions across the cancer continuum. RECENT FINDINGS: Although prognosticating life expectancy is difficult, referrals for rehabilitation interventions appear to be affected by physician attitudes towards patients with advanced disease, in part because of misconceptions about the nature of rehabilitation for oncology patients...
2017: Current Physical Medicine and Rehabilitation Reports
https://www.readbyqxmd.com/read/28455547/associations-of-sleep-disturbance-with-physical-function-and-cognition-in-older-adults-with-cancer
#11
Kah Poh Loh, Chintan Pandya, Jason Zittel, Sindhuja Kadambi, Marie Flannery, Natalie Reizine, Allison Magnuson, Giovanna Braganza, Karen Mustian, William Dale, Paul Duberstein, Supriya Gupta Mohile
PURPOSE: Although sleep disturbances are common in older adults, studies evaluating the prevalence of sleep disturbance and its influence on functional outcomes in older adults with cancer are few. In this study, we examined the prevalence of sleep disturbance and its association with physical function and cognition in older adults with cancer. METHODS: This is a cross-sectional study of patients who were referred and evaluated in the Specialized Oncology Care & Research in the Elderly (SOCARE) clinics at the Universities of Rochester and Chicago from May 2011 to October 2015...
April 28, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28431396/skeletal-muscle-measures-and-physical-function-in-older-adults-with-cancer-sarcopenia-or-myopenia
#12
Grant R Williams, Allison M Deal, Hyman B Muss, Marc S Weinberg, Hanna K Sanoff, Kirsten A Nyrop, Mackenzi Pergolotti, Shlomit Strulov Shachar
BACKGROUND: Skeletal muscle loss, commonly known as sarcopenia, is highly prevalent in older adults and linked with adverse outcomes in cancer, yet the definition and role of sarcopenia remains uncertain. The aim of this study was to examine the association of Computerized Tomography (CT) assessed skeletal muscle measures with physical function in older adults with cancer. RESULTS: CTs for 185 patients were available. Median age 73 (IQR 68-76) and 56.5% female. After controlling for sex and BMI, we found no evidence that SMI was associated with physical function impairments...
May 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28411479/aged-patients-with-metastatic-castration-resistant-prostate-cancer-should-we-treat-with-chemotherapy
#13
REVIEW
Miguel Ángel Climent, Ma Dolores Torregrosa, Sergio Vázquez, Regina Gironés, José Angel Arranz
Prostate cancer largely affects aged men and as life expectancy continues to increase, it is likely to be a growing burden requiring an adequate management. Aging is a heterogeneous process, thus, to assess the individual state of health when making decisions is essential. Comprehensive geriatric assessment allows a detailed evaluation of the state of health of a specific subject and can modify the therapeutic decision. It is still not commonly used because it is time consuming. Chemotherapy should be administered equally in aged well-fit patients as in the general population as per the SIOG (International society of geriatric oncology) recommendations for geriatric evaluation and treatment in prostate cancer patients...
April 2017: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/28408619/data-linkage-to-improve-geriatric-oncology-research-a-feasibility-study
#14
Jennifer L Lund, Anne-Marie Meyer, Allison M Deal, Bong-Jin Choi, YunKyung Chang, Grant R Williams, Mackenzi Pergolotti, Emily J Guerard, Hyman B Muss, Hanna K Sanoff
Older adults (aged 65 years and older) diagnosed with cancer account for most cancer-related morbidity and mortality in the United States but are often underrepresented on clinical trials. Recent attention from a variety of professional, research, regulatory, and patient advocacy groups has centered on data linkage and data sharing as a means to capture patient information and outcomes outside of clinical trials to accelerate progress in the fight against cancer. The development of a more robust observational research data infrastructure would help to address gaps in the evidence base regarding optimal approaches to treating cancer among the growing and complex population of older adults...
April 13, 2017: Oncologist
https://www.readbyqxmd.com/read/28405846/cancer-specific-geriatric-assessment-and-quality-of-life-important-factors-in-caring-for-older-patients-with-aggressive-b-cell-lymphoma
#15
Karin Ribi, Stéphanie Rondeau, Felicitas Hitz, Ulrich Mey, Milica Enoiu, Thomas Pabst, Anastasios Stathis, Natalie Fischer, Kerri M Clough-Gorr
PURPOSE: To evaluate the efficacy and tolerability of chemotherapy, a geriatric assessment is recommended in elderly patients with cancer. We aimed to characterize and compare patients with aggressive lymphoma by objective response and survival status based on pre-treatment cancer-specific geriatric (C-SGA) and quality of life (QoL) assessments. METHODS: Patients not eligible for anthracycline-based first-line therapy or intensive salvage regimens completed C-SGA and QoL assessment before and after a rituximab-bendamustine-lenalidomide (R-BL) treatment in a phase II clinical trial...
April 13, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28403222/comorbidity-and-dementia-a-nationwide-survey-in-taiwan
#16
Ting-Bin Chen, Szu-Yu Yiao, Yu Sun, Huey-Jane Lee, Shu-Chien Yang, Ming-Jang Chiu, Ta-Fu Chen, Ker-Neng Lin, Li-Yu Tang, Chung-Chih Lin, Pei-Ning Wang
BACKGROUND: Comorbid medical diseases are highly prevalent in the geriatric population, imposing hardship on healthcare services for demented individuals. Dementia also complicates clinical care for other co-existing medical conditions. This study investigated the comorbidities associated with dementia in the elderly population aged 65 years and over in Taiwan. METHODS: We conducted a nationwide, population-based, cross-sectional survey; participants were selected by computerized random sampling from all 19 Taiwan counties between December 2011 and March 2013...
2017: PloS One
https://www.readbyqxmd.com/read/28400051/frailty-and-vulnerability-as-predictors-of-radiotoxicity-in-older-adults-a-longitudinal-study-in-peru
#17
Fernando M Runzer-Colmenares, Diego Urrunaga-Pastor, Luis G Aguirre, C Mahony Reategui-Rivera, José F Parodi, Alvaro Taype-Rondan
BACKGROUND AND OBJECTIVE: To assess the association between frailty/vulnerability and the development of radiotoxicity in older adults at a hospital in Peru. MATERIAL AND METHODS: Cohort study that included patients with cancer with medical recommendation of radiotherapy, who attended the outpatient department of geriatrics at Naval Medical Center (Lima, Peru) between 2013 and 2015. Before receiving radiation therapy sessions, we measured frailty using Fried phenotype, and vulnerability using VES-13 and G-8 scales...
April 8, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/28399028/pathologic-and-treatment-outcomes-among-a-geriatric-population-of-endometrial-cancer-patients-an-nrg-oncology-gynecologic-oncology-group-ancillary-data-analysis-of-lap2
#18
Erin A Bishop, James J Java, Kathleen N Moore, Joan L Walker
OBJECTIVES: Elderly endometrial cancer patients have worse disease-specific survival than their younger counterparts, but the cause for this discrepancy is unknown. The goal of this analysis is to compare outcomes by age in a fully staged elderly endometrial cancer population. METHODS/MATERIALS: This is an analysis of patients on Gynecologic Oncology Group Study (GOG) LAP2, which included clinically early stage endometrial cancer patients randomized to laparotomy versus laparoscopy for surgical staging...
May 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28391026/radiopharmaceuticals-in-the-elderly-cancer-patient-practical-considerations-with-a-focus-on-prostate-cancer-therapy-a-position-paper-from-the-international-society-of-geriatric-oncology-task-force
#19
John O Prior, Silke Gillessen, Manfred Wirth, William Dale, Matti Aapro, Wim J G Oyen
Molecular imaging using radiopharmaceuticals has a clear role in visualising the presence and extent of tumour at diagnosis and monitoring response to therapy. Such imaging provides prognostic and predictive information relevant to management, e.g. by quantifying active tumour mass using positron emission tomography/computed tomography (PET/CT). As these techniques require only pharmacologically inactive doses, age and potential frailty are generally not important. However, this may be different for therapy involving radionuclides because the radiation can impact normal bodily function (e...
April 6, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28366577/use-of-geriatric-assessment-tools-in-selecting-therapies-in-women-aged-%C3%A2-70%C3%A2-years-with-hormone-receptor-positive-early-stage-breast-cancer-preliminary-experience-with-a-quality-improvement-initiative
#20
Jean L Wright, Arti Parekh, Yao Yao Pollock, Nancy Schoenborn, Karen L Smith, Colette Magnant, Vered Stearns
PURPOSE: To develop a multidisciplinary algorithmic approach to management of women aged ≥70 years with clinically staged T1N0 hormone receptor-positive breast cancer, including geriatric assessments predicting life expectancy and the likelihood of functional decline in the near future, in the context of a program-wide quality improvement initiative, to better select patients for therapeutic interventions. METHODS AND MATERIALS: Two geriatric assessment tools, the Combined Lee-Schonberg Index and the Vulnerable Elderly Scale, were introduced into our clinical workflow to predict long-term mortality and likelihood of functional decline...
January 29, 2017: International Journal of Radiation Oncology, Biology, Physics
keyword
keyword
7938
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"