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https://www.readbyqxmd.com/read/28328090/bronchiolitis-score-of-sant-joan-de-d%C3%A3-u-brosjod-score-validation-and-usefulness
#1
Mònica Balaguer, Carme Alejandre, David Vila, Elisabeth Esteban, Josep L Carrasco, Francisco José Cambra, Iolanda Jordan
OBJECTIVE: To validate the bronchiolitis score of Sant Joan de Déu (BROSJOD) and to examine the previously defined scoring cutoff. PATIENTS AND METHODS: Prospective, observational study. BROSJOD scoring was done by two independent physicians (at admission, 24 and 48 hr). Internal consistency of the score was assessed using Cronbach's α. To determine inter-rater reliability, the concordance correlation coefficient estimated as an intraclass correlation coefficient (CCC) and limits of agreement estimated as the 90% total deviation index (TDI) were estimated...
April 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28259309/clinician-attitudes-skills-motivations-and-experience-following-the-implementation-of-clinical-decision-support-tools-in-a-large-dental-practice
#2
Elizabeth Mertz, Cynthia Wides, Joel White
OBJECTIVE: This study assesses dental clinicians' pre- and post-implementation attitudes, skills, and experiences with three clinical decision support (CDS) tools built into the electronic health record (EHR) of a multi-specialty group dental practice. METHODS: Electronic surveys designed to examine factors for acceptance of EHR-based CDS tools including caries management by risk assessment (CAMBRA), periodontal disease management by risk assessment (PEMBRA) and a risk assessment-based Proactive Dental Care Plan (PDCP) were distributed to all Willamette Dental Group employees at 2 time points; 3 months pre-implementation (Fall 2013) and 15 months after implementation (winter 2015)...
March 2017: Journal of Evidence-based Dental Practice
https://www.readbyqxmd.com/read/28236538/understanding-variations-in-the-use-of-hypofractionated-radiotherapy-and-its-specific-indications-for-breast-cancer-a-mixed-methods-study
#3
Joan Prades, Manel Algara, Josep A Espinàs, Blanca Farrús, Meritxell Arenas, Victoria Reyes, Virginia García-Reglero, Maria Josep Cambra, Esther Rubio, Lluis Anglada, Arantxa Eraso, Agustí Pedro, Maria J Fuentes-Raspall, Victòria Tuset, Judit Solà, Josep M Borras
BACKGROUND AND PURPOSE: Radiation oncology guidelines favour hypofractionated whole-breast radiotherapy (HWBRT) over more conventional schemes in the conservative treatment of breast cancer, but its adoption still varies in clinical practice. This study assessed the patterns of HWBRT adoption in Catalonia (Spain). MATERIAL AND METHODS: We used a mixed-methods approach based on an explanatory sequential design, first collecting and analysing quantitative data on HWBRT use (>2...
February 21, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28211491/interference-between-variants-of-peach-latent-mosaic-viroid-reveals-novel-features-of-its-fitness-landscape-implications-for-detection
#4
Pedro Serra, Edson Bertolini, M Carmen Martínez, Mariano Cambra, Ricardo Flores
Natural populations of peach latent mosaic viroid (PLMVd) are complex mixtures of variants. During routine testing, TaqMan rtRT-PCR and RNA gel-blot hybridization produced discordant results with some PLMVd isolates. Analysis of the corresponding populations showed that they were exclusively composed of variants (of class II) with a structural domain different from that of the reference and many other variants (of class I) targeted by the TaqMan rtRT-PCR probe. Bioassays in peach revealed that a representative PLMVd variant of class II replicated without symptoms, generated a progeny with low nucleotide diversity, and, intriguingly, outcompeted a representative symptomatic variant of class I when co-inoculated in equimolecular amounts...
February 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28196820/combined-use-of-neurally-adjusted-ventilatory-assist-nava-and-vertical-expandable-prostethic-titanium-rib-veptr-in-a-patient-with-spondylocostal-dysostosis-and-associated-bronchomalacia
#5
Martí Pons-Odena, Alba Verges, Natalia Arza, Francisco José Cambra
Jarcho-Levin syndrome is a rare disorder characterised by defects in vertebral and costal segmentation of varying severity. Respiratory complications are the main cause of death or severe comorbidity due to a restrictive rib cage. A 3 months old infant with Spondylocostal dysostosis and associated bronchomalacia experiencing severe asynchrony during the weaning process is reported. The Neurally Adjusted Ventilatory Assist (NAVA) mode was used to improve adaptation to mechanical ventilation after Vertical Expandable Prosthetic Titanium Ribs (VEPTRs) were implanted...
February 14, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28194687/fecal-incontinence-and-radiation-dose-on-anal-sphincter-in-patients-with-locally-advanced-rectal-cancer-larc-treated-with-preoperative-chemoradiotherapy-a-retrospective-single-institutional-study
#6
F Arias, C Eito, G Asín, I Mora, K Cambra, F Mañeru, B Ibáñez, L Arbea, A Viudez, I Hernández, J I Arrarás, M Errasti, M Barrado, M Campo, I Visus, S Flamarique, M A Ciga
BACKGROUND: The objective of the study is to determine the correlations among the variables of dose and the sphincter function (SF) in patients with locally advanced rectal cancer treated with preoperative capecitabine/radiotherapy followed by low anterior resection (LAR) + TME. METHODS: We retrospectively reviewed 92 consecutive patients with LARC treated at our center with LAR from 2006 and more than 2 years free from disease. We re-contoured the anal sphincters (AS) of patients with the help of the radiologist...
February 13, 2017: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/28157810/bayes-to-the-rescue-continuous-positive-airway-pressure-has-less-mortality-than-high-flow-oxygen
#7
Vicent Modesto I Alapont, Robinder G Khemani, Alberto Medina, Pablo Del Villar Guerra, Alfred Molina Cambra
OBJECTIVES: The merits of high-flow nasal cannula oxygen versus bubble continuous positive airway pressure are debated in children with pneumonia, with suggestions that randomized controlled trials are needed. In light of a previous randomized controlled trial showing a trend for lower mortality with bubble continuous positive airway pressure, we sought to determine the probability that a new randomized controlled trial would find high-flow nasal cannula oxygen superior to bubble continuous positive airway pressure through a "robust" Bayesian analysis...
February 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28111928/electrospun-poly-hydroxybutyrate-scaffolds-promote-engraftment-of-human-skin-equivalents-via-macrophage-m2-polarization-and-angiogenesis
#8
Delia Castellano, Ana Sanchis, María Blanes, Mª Dolores Pérez Del Caz, Amparo Ruiz-Saurí, Marina Piquer, Beatriz Pelacho, B Marco, Nahuel Garcia, Imelda Ontoria-Oviedo, Vicente Cambra, Felipe Prosper, Pilar Sepúlveda
Human dermo-epidermal skin equivalents (DE) comprising in vitro expanded autologous keratinocytes and fibroblasts are a good option for massive burn treatment. However, the lengthy expansion time required to obtain sufficient surface to cover an extensive burn together with the challenging surgical procedure limits their clinical use. The integration of DE and biodegradable scaffolds has been proposed in an effort to enhance their mechanical properties. Here, we show that poly(hydroxybutyrate) electrospun scaffolds (PHB) present good biocompatibility both in vitro and in vivo and are superior to poly-ε-caprolactone electrospun scaffolds (PCL) as a substrate for skin reconstruction...
January 23, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/28054350/daily-variation-of-uv-induced-erythema-and-the-action-of-solar-filters
#9
Ana Flo, Ana C Calpena, Antoni Díez-Noguera, Alfons Del Pozo, Trinitat Cambras
UV rays may cause several degrees of skin damage, which makes sunscreen research necessary. In addition, skin sensitivity shows daily variations, which can interfere in the detection of the efficacy of the filters. Here, we studied the UV-induced erythema in hairless rats at two times of the day (light and darkness) using a colorimeter method. The effect of an emulsion with solar filters with or without melatonin was also assayed. Results indicate that the value of a* (from CIELAB color space values L* a* b) was the most useful variable to evaluate the erythema...
March 2017: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/28039732/erratum-quality-of-life-in-long-term-premenopausal-early-stage-breast-cancer-survivors-from-spain-effects-of-surgery-and-time-since-surgery
#10
J I Arraras, J J Illarramendi, S de la Cruz, G Asin, A Manterola, B Ibanez, E Salgado, K Cambra, U Zarandona, M A Dominguez, R Vera
In this article published in Volume 21, issue 5, the authors' names were incorrectly stated in the Pubmed abstract as: "Ignacio Arraras J(1), Juan Illarramendi J, de la Cruz S, Asin G, Manterola A, Ibanez B, Salgado E, Cambra K, Zarandona U, Angel Dominguez M, Vera R.". The correct authors' names are: "Arraras JI(1), Illarramendi JJ, de la Cruz S, Asin G, Manterola A, Ibanez B, Salgado E, Cambra K, Zarandona U, Dominguez MA, Vera R.". This error appeared only in the PubMed database and not in the print form of the Journal...
November 2016: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28032875/insomnio-en-pacientes-que-ingresan-en-unidades-de-hospitalizaci%C3%A3-n-psiqui%C3%A3-tricas
#11
J Antomás Osés, C Gárriz Murillo, S Huarte Del Barrio, K Cambra Contín, B Ibáñez Beroiz
Fundamento. El objetivo de este estudio es estimar la prevalencia de insomnio en pacientes que precisaron ingresar en unidades psiquiátricas hospitalarias de corta estancia.Metodología. Se diseñó un estudio observacional descriptivo en el que tomaron parte 16 unidades de hospitalización psiquiátrica breve de adultos de España. El instrumento utilizado fue la Escala Atenas de Insomnio.Resultados. Se reclutó a 425 pacientes, obtuvieron un valor medio de la puntuación global de la Escala Atenas de Insomnio de 8,56 (DE: 5,78)...
December 30, 2016: Anales del Sistema Sanitario de Navarra
https://www.readbyqxmd.com/read/27988742/review-of-i-frigitilla-i-williams-in-bartholomay-i-et-al-i-2015-with-description-of-a-new-species-from-panama-hymenoptera-mutillidae
#12
Roberto A Cambra, Denis J Brothers, Diomedes Quintero
Frigitilla panamensis Cambra, Brothers & Quintero sp. nov., from Panama, based on females, is described and illustrated. This new species represents the northernmost distribution record for the Neotropical genus Frigitilla Williams in Bartholomay et al., 2015. New synonymy and combination are proposed for Frigitilla simulatrix (F. Smith, 1879), comb. nov. =Mutilla frigidula Cresson, 1902, syn. nov. A lectotype is designated for Mutilla simulatrix F. Smith, 1879. The differentiating characters for the genus are briefly discussed...
November 10, 2016: Zootaxa
https://www.readbyqxmd.com/read/27889567/prognostic-value-of-plasma-apelin-concentrations-at-admission-in-patients-with-st-segment-elevation-acute-myocardial-infarction
#13
Jordi Sans-Roselló, Gregori Casals, Xavier Rossello, Bernardino González de la Presa, Montserrat Vila, Albert Duran-Cambra, Manuel Morales-Ruiz, Andreu Ferrero-Gregori, Wladimiro Jiménez, Alessandro Sionis
BACKGROUND: The use of plasma biomarkers is relevant for the prognosis of ST-segment elevation myocardial infarction (STEMI) patients. Apelin, an adipocytokine, plays a pivotal role in the pathophysiology of both ischemia/reperfusion injury and its potential subsequent heart failure. We evaluated apelin concentrations at admission as a biomarker to assess risk of 6-month mortality. METHODS: Consecutive patients with STEMI were recruited from January 2012 to January 2013 (n=250)...
November 24, 2016: Clinical Biochemistry
https://www.readbyqxmd.com/read/27801525/complement-c3f-allotype-synthesized-by-liver-recipient-modifies-transplantation-outcome-independently-from-donor-hepatic-c3
#14
Diana María Valero-Hervás, Elena Sánchez-Zapardiel, María José Castro, Fernando Gallego-Bustos, Félix Cambra, Iago Justo, Rocío Laguna-Goya, Carlos Jiménez-Romero, Enrique Moreno, Francisco López-Medrano, Rafael San Juan, Mario Fernández-Ruiz, José María Aguado, Estela Paz-Artal
Complement component 3 (C3) presents both slow (C3S) and fast (C3F) variants, which can be locally-produced and activated by immune system cells. We studied C3 recipient variants in 483 liver transplant patients by RT-PCR-HRM to determine their effect on graft outcome during the first year post-transplantation. Allograft survival was significantly decreased in C3FF recipients (C3SS 95% vs. C3FS 91% vs. C3FF 83%; p=0.01) or C3F allele carriers (C3F-absence 95% vs. C3F-presence 90%, p=0.02). C3FF genotype or presence of C3F allele independently increased risk for allograft loss (OR: 2...
November 1, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27729015/sex-and-age-differences-in-the-achievement-of-control-targets-in-patients-with-type-2-diabetes-results-from-a-population-based-study-in-a-south-european-region
#15
K Cambra, A Galbete, L Forga, O Lecea, M J Ariz, C Moreno-Iribas, F Aizpuru, B Ibañez
BACKGROUND: We aimed to determine the degree to which control targets of glycaemia and cardiovascular risk factors were achieved among patients with type 2 diabetes and to investigate sex- and age-related differences in this population. METHODS: This cross-sectional, population-based study was conducted in Spain. Glycated hemoglobin (HbA1c), blood pressure, LDL-c, HDL-c, triglycerides, BMI, and smoking history were obtained from electronic clinical primary care records (n = 32,638 cases)...
October 12, 2016: BMC Family Practice
https://www.readbyqxmd.com/read/27644893/melatonin-pharmacokinetics-after-transdermal-administration-changes-according-to-the-time-of-the-day
#16
Ana Flo, Trinitat Cambras, Antoni Díez-Noguera, Ana Calpena
Melatonin is a neurohormone with multiple and different actions, such as chronobiotic or antioxidant. Melatonin is usually orally administered, but dermal administration is also useful in dermatological diseases or as adjuvant to certain skin treatments. Here, we studied the variability of the pharmacokinetics of melatonin and its metabolite AFMK, when melatonin is transdermally administered to Hairless rat at two different times of day (Zeitgeber Time 4 (ZT4) and ZT16). Moreover, in order to obtain the bioavailability, kinetics after intravenous administration was also studied...
January 1, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/27554833/missing-patients-in-major-trauma-registry-of-navarre-incidence-and-pattern
#17
B A Ali, M Fortún, T Belzunegui, B Ibañez, K Cambra, A Galbete
BACKGROUND: Trauma registries (TR) collect information about trauma patients according to inclusion criteria, and it helps to establish protocols to improve care. However, all TR deal with incompleteness. The aim of this study is to assess the number of patients not included despite fulfilling inclusion criteria in our regional TR and identifying the predictors for being missing. METHODS: The sample was randomly selected. Two months of each year from 2010 to 2014 (5 years) were selected, and medical files of all patients attended in the emergency department room during those months were studied...
August 23, 2016: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/27553044/impact-of-pulmonary-artery-catheter-use-on-short-and-long-term-mortality-in-patients-with-cardiogenic-shock
#18
Xavier Rossello, Montserrat Vila, Mercedes Rivas-Lasarte, Andreu Ferrero-Gregori, Jordi Sans-Roselló, Albert Duran-Cambra, Alessandro Sionis
OBJECTIVES: The impact of pulmonary artery catheterization (PAC) on survival in patients with cardiogenic shock (CS) is not well established. This study aimed to assess whether Swan-Ganz catheter monitoring is related to short- and long-term mortality in patients with CS. METHODS: One hundred and twenty-nine consecutive patients with a first admission for CS were prospectively enrolled in a single-center registry between December 2005 and May 2009, and were subsequently followed up over 5...
2017: Cardiology
https://www.readbyqxmd.com/read/27485947/geometric-morphometrics-reveals-restrictions-on-the-shape-of-the-female-os-coxae
#19
Nieves Candelas González, Josefina Rascón Pérez, Beatriz Chamero, Oscar Cambra-Moo, Armando González Martín
The methodology for sex determination in human skeletal remains depends on the different bone morphologies presented by men and women. Due to their direct implications in reproduction, the whole pelvis, particularly the os coxae, shows different characteristics in either sex. The sacrum and the os coxae constitute the birth canal. In this research study, the os coxae shape is analyzed using geometric morphometrics, providing information on morphology, regardless of size or any other factor beyond the geometry itself...
January 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/27433851/how-hyperprolactinemia-affects-sexual-function-in-patients-under-antipsychotic-treatment
#20
Elena Rubio-Abadal, Núria Del Cacho, Gerard Saenz-Navarrete, Belen Arranz, Rosa-Maria Cambra, Daniel Cuadras, Demián Rodante, Csaba Fehér, Mercedes Roca, Vanessa Barneda, Judith Usall
OBJECTIVE: We aimed to study the relationship between hyperprolactinemia (HPRL) and sexual dysfunction (SED) in a sample of patients being prescribed a dose-stable antipsychotic medication, and to evaluate sex differences in the prevalence of HPRL and SED and their relationship. METHOD: A cross-sectional study was carried out including patients between 18 and 55 years of age with a psychotic spectrum diagnosis who were attending community mental health services or hospitalized in medium and long stay units...
October 2016: Journal of Clinical Psychopharmacology
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