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https://www.readbyqxmd.com/read/29600870/integrating-caries-management-by-risk-assessment-cambra-and-prevention-strategies-into-the-contemporary-dental-practice
#1
Peter Rechmann, Richard Kinsel, John D B Featherstone
In the past, the dental profession has adhered to a rigid tenet: remove decay from a tooth and then restore, a mindset that has been proverbially dubbed as "drill and fill." Today, dental caries is recognized as an infectious disease that affects children and adults throughout life. The philosophy of CAries Management By Risk Assessment, or CAMBRA®, represents a paradigm shift. The CAMBRA concept provides the dentist with scientific, evidence-based solutions with which to approach treatment of dental caries disease...
April 2018: Compendium of Continuing Education in Dentistry
https://www.readbyqxmd.com/read/29587788/socioeconomic-inequalities-in-cardiometabolic-control-in-patients-with-type-2-diabetes
#2
Berta Ibáñez, Arkaitz Galbete, María José Goñi, Luis Forga, Laura Arnedo, Felipe Aizpuru, Julián Librero, Oscar Lecea, Koldo Cambra
BACKGROUND: The aim of this study was to determine if the achievement of control targets in patients with type 2 diabetes was associated with personal socioeconomic factors and if these associations were sex-dependent. METHODS: This cross-sectional, population-based study was conducted in Spain. Glycated haemoglobin (HbA1c) level and other clinical parameters were obtained from electronic primary care records (n = 32,638 cases). Socioeconomic status was determined using education level and yearly income...
March 27, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29544939/circulating-microparticles-are-associated-with-clinical-severity-of-persistent-st-segment-elevation-myocardial-infarction-complicated-with-cardiogenic-shock
#3
A Sionis, R Suades, J Sans-Roselló, M Sánchez-Martínez, J Crespo, T Padró, J Cubedo, A Ferrero-Gregori, M Vila-Perales, A Duran-Cambra, L Badimon
BACKGROUND: Cardiogenic shock (CS) is the leading cause of death in patients admitted for acute myocardial infarction (MI). Despite the recent advances in reperfusion and medical treatment mortality remains unacceptably high. Whether cells of the blood compartment in CS-patients are activated and release microparticles (cMPs) that may be both messengers and biomarkers of cell damage is not known. We aimed to investigate the cMP subtypes and parental activated cells of ST-elevation MI (STEMI)-patients complicated by CS and that of non-CS STEMI-patients (non-CS) in order to identify a cMP signature that could aid CS patient's risk stratification...
May 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29517150/tamoxifen-induced-radiation-recall-dermatitis-in-a-breast-cancer-patient
#4
Israel Barco, Manel Fraile, MCarmen Vidal, Maria Jose Cambra, Elena Vallejo, Jordi Deu, Sonia González, Nuria Giménez, Antoni Pessarrodona, Antonio García-Fernández
No abstract text is available yet for this article.
March 8, 2018: Breast Journal
https://www.readbyqxmd.com/read/29501151/renewable-chemiluminescence-optosensors-based-on-implementation-of-bead-injection-principle-with-multicommutation
#5
Juan C Domínguez-Romero, Bienvenida Gilbert-López, Miriam Beneito-Cambra, Antonio Molina-Díaz
In this work, the implementation of Bead Injection with multicommutation-based flow systems is reported. A surface renewable chemiluminescence (CL) flow sensor is presented based on the use of CL reaction of luminol with H2 O2 . Dowex 1 × 8 beads with immobilized luminol onto them were injected in the flow system by means of a six-port rotary valve and were accommodated into a 1 mm optical glass flow cell placed just in front of the rectangular photosensor window with the same size than the cell wall. Automatic computer-controlled manipulation of both reagents and sample solutions was undertaken using a multicommutated flow system which comprises five three-way solenoid valves, a home-made electronic interface and a Java-written software...
May 15, 2018: Talanta
https://www.readbyqxmd.com/read/29501143/dilute-and-shoot-coupled-to-nanoflow-liquid-chromatography-high-resolution-mass-spectrometry-for-the-determination-of-drugs-of-abuse-and-sport-drugs-in-human-urine
#6
Jaime Alcántara-Durán, David Moreno-González, Miriam Beneito-Cambra, Juan F García-Reyes
In this work, a sensitive nanoflow liquid chromatography high-resolution mass spectrometry screening method has been developed for the determination of multiclass drugs of abuse and sport drugs in human urine. 81 drugs belonging to different multiclass pharmaceuticals were targeted. The method is based on the use of a nanoLC column (75 µm × 150 mm, 3 µm particle size and 100 Å pore) with the nanospray emitter tip integrated so that dead volumes are significantly minimized. Data acquisition method included both full-scan and all ion fragmentation experiments using an Orbitrap analyser (Q-Exactive) operated in the positive ionization mode...
May 15, 2018: Talanta
https://www.readbyqxmd.com/read/29496209/comment-upon-basilar-portion-porosity-a-pathological-lesion-possibly-associated-with-infantile-scurvy
#7
A González Martín, F J Robles Rodríguez, O Cambra-Moo, J Rascón Pérez, M Campo Martín
No abstract text is available yet for this article.
March 2018: International Journal of Paleopathology
https://www.readbyqxmd.com/read/29355423/the-evidence-for-caries-management-by-risk-assessment-cambra%C3%A2
#8
J D B Featherstone, B W Chaffee
A system for Caries Management by Risk Assessment (CAMBRA® ) has been developed in California. The purpose of this article is to summarize the science behind the methodology, the history of the development of CAMBRA, and the outcomes of clinical application. The CAMBRA caries risk assessment (CRA) tool for ages 6 y through adult has been used at the University of California, San Francisco (UCSF), for 14 y, and outcome studies involving thousands of patients have been conducted. Three outcomes assessments, each on different patient cohorts, demonstrated a clear relationship between CAMBRA-CRA risk levels of low, moderate, high, and extreme with cavitation or lesions into dentin (by radiograph) at follow-up...
February 2018: Advances in Dental Research
https://www.readbyqxmd.com/read/29355409/changes-in-caries-risk-in-a-practice-based-randomized-controlled-trial
#9
P Rechmann, B W Chaffee, B M T Rechmann, J D B Featherstone
To demonstrate that Caries Management by Risk Assessment (CAMBRA) can be successfully implemented in dental practice, 30 dentists were recruited to perform a 2-y CAMBRA trial. Twenty-one dentists (18 private practices, 3 community clinics) participated in a randomized, controlled, parallel-arm, double-blind clinical trial with individual-level assignment of 460 participants to standard of care (control) versus active CAMBRA treatment (intervention). Control or active antimicrobial and remineralizing agents were dispensed at baseline and 6-, 12-, 18-, and 24-mo recall visits according to risk level and assigned treatment arm...
February 2018: Advances in Dental Research
https://www.readbyqxmd.com/read/29343939/kinetics-of-procalcitonin-in-pediatric-patients-on-extracorporeal-membrane-oxygenation
#10
REVIEW
Sara Bobillo, Javier Rodríguez-Fanjul, Anna Solé, Julio Moreno, Mònica Balaguer, Elisabeth Esteban, Francisco José Cambra, Iolanda Jordan
Objectives: To assess the kinetics of procalcitonin (PCT) and C-reactive protein (CRP) in pediatric patients who required extracorporeal membrane oxygenation (ECMO) and to analyze its relationship with morbidity and mortality. Patients and methods: Prospective observational study including pediatric patients who required ECMO. Both PCT and CRP were sequentially drawn before ECMO (P0) and until 72 hours after ECMO. Results: A total of 40 patients were recruited...
2018: Biomarker Insights
https://www.readbyqxmd.com/read/29332796/direct-olive-oil-analysis-by-mass-spectrometry-a-comparison-of-different-ambient-ionization-methods
#11
Felipe J Lara-Ortega, Miriam Beneito-Cambra, José Robles-Molina, Juan F García-Reyes, Bienvenida Gilbert-López, Antonio Molina-Díaz
Analytical methods based on ambient ionization mass spectrometry (AIMS) combine the classic outstanding performance of mass spectrometry in terms of sensitivity and selectivity along with convenient features related to the lack of sample workup required. In this work, the performance of different mass spectrometry-based methods has been assessed for the direct analyses of virgin olive oil for quality purposes. Two sets of experiments have been setup: (1) direct analysis of untreated olive oil using AIMS methods such as Low-Temperature Plasma Mass Spectrometry (LTP-MS) or paper spray mass spectrometry (PS-MS); or alternatively (2) the use of atmospheric pressure ionization (API) mass spectrometry by direct infusion of a diluted sample through either atmospheric pressure chemical ionization (APCI) or electrospray (ESI) ionization sources...
April 1, 2018: Talanta
https://www.readbyqxmd.com/read/29301527/calibration-of-dentists-for-caries-management-by-risk-assessment-research-in-a-practice-based-research-network-cambra-pbrn
#12
Peter Rechmann, Bonnie Jue, William Santo, Beate M T Rechmann, John D B Featherstone
BACKGROUND: To prove that Caries Management by Risk Assessment (CAMBRA) can be successfully implemented in dental practices outside of the university setting, dentists in the San Francisco Bay Area (CA) were approached to participate in a Practice Based Research Network (PBRN) study. The overall goal of the CAMBRA-PBRN study was to recruit 30 dentists to perform a two-year study involving approximately 900 patients. Goal of the calibration study was to standardize and calibrate dentists potentially participating in the CAMBRA-PBRN study...
January 4, 2018: BMC Oral Health
https://www.readbyqxmd.com/read/29229356/double-inferior-vena-cava-with-double-left-renal-vein
#13
Lucía González González, Félix Cambra Molero, Néstor Taboada Mostajo, Luis Carlos Jiménez Romero
No abstract text is available yet for this article.
December 8, 2017: Cirugía Española
https://www.readbyqxmd.com/read/29211510/forced-desynchronization-model-for-a-diurnal-primate
#14
Crhistiane A Silva, Laís I M Melo, Alina R Pires, Jordana C Barbalho, Andreia V Melo, Diego A C Fernandes, Everly B Oliveira, Carolina V M Azevedo, Trinitat Cambras, Antoni Díez-Noguera, John Fontenele-Araujo
The circadian system is organized in a hierarchy of multiple oscillators, with the suprachiasmatic nucleus (SCN) as the master oscillator in mammals. The SCN is formed by a group of coupled cell oscillators. Knowledge of this coupling mechanism is essential to understanding entrainment and the expression of circadian rhythms. Some authors suggest that light-dark (LD) cycles with periods near the limit of entrainment may be good models for promoting internal desynchronization, providing knowledge about the coupling mechanism...
January 2018: Chronobiology International
https://www.readbyqxmd.com/read/29153997/first-investigations-for-the-characterization-of-glucosamine-6-phosphate-synthase-by-capillary-electrophoresis
#15
Miriam Beneito-Cambra, Pierre Gareil, Bernard Badet, Marie-Ange Badet-Denisot, Nathalie Delaunay
The enzyme glucosamine-6-phosphate synthase (GlmS) is an important point of metabolic control in biosynthesis of amino sugar-containing macromolecules and is therefore a potential target in order to design antibacterial and antifungal drugs. It has two oligomerization states, which are the active dimer and the inactive hexamer. For the first time, the potential of CE to separate and quantify the two forms was studied. After incubating GlmS with the d-glucosamine 6-phosphate (GlcN6P) inhibitor, an electrolyte based on sodium phosphate at pH 7...
January 1, 2018: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29141708/sensitive-detection-of-neonicotinoid-insecticides-and-other-selected-pesticides-in-pollen-and-nectar-using-nanoflow-liquid-chromatography-orbitrap-tandem-mass-spectrometry
#16
David Moreno-González, Jaime Alcántara-Durán, Bienvenida Gilbert-López, Miriam Beneito-Cambra, Víctor M Cutillas, Łukasz Rajski, Antonio Molina-Díaz, Juan F García-Reyes
In this work, a new method based on nanoflow LC with high-resolution MS was developed for the determination of eight pesticides in pollen and nectar samples, including neonicotinoid insecticides and other selected pesticides commonly found in bees and beeswax. Detection was undertaken with a hybrid quadrupole-Orbitrap mass spectrometer (Q Exactive™) equipped with a commercial nanospray ion source. The extraction of pesticides from pollen samples was performed by a modified micro-QuEChERS method scaled down to Eppendorf tubes, whereas nectar samples were simply diluted with a water-methanol (95 + 5, v/v) solution...
March 1, 2018: Journal of AOAC International
https://www.readbyqxmd.com/read/29130467/-a-comparative-study-of-three-systems-for-quantifying-the-spike-and-wave-index-in-patients-with-continuous-spikes-and-waves-during-slow-sleep
#17
G Azcona, I G Gurtubay, A Mosquera, B Ibanez, K Cambra, S Aguilera-Albesa, M E Yoldi-Petri
INTRODUCTION: Continuous spikes and waves during slow sleep (CSWS) is an epileptic encephalopathy of childhood with a pattern of epileptiform discharges during sleep, which, if prolonged over time, produce severe neuropsychological impairment. Quantification of the paroxysms by means of a spike and wave index (SWI) > 85% establishes a presumptive diagnosis and allows early therapy to be started to prevent such impairment. AIMS: To compare the results of the classic method for calculating the SWI against two proposals that optimise the relation between the analysis time employed and the diagnostic sensitivity...
November 16, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/29106285/liver-kidney-simultaneous-transplantation-in-adult-patients-with-primary-hyperoxaluria-experience-at-hospital-universitario-12-de-octubre
#18
Javier Martínez Caballero, Alberto Marcacuzco Quinto, Iago Justo Alonso, Oana Anisa Nutu, Alejandro Manrique Municio, Jorge Calvo Pulido, Félix Cambra Molero, Óscar Caso Maestro, Carlos Jiménez Romero
Primary hyperoxaluria (PH) is a metabolic liver disease with an autosomal recessive inheritance that results in oxalate overproduction that cannot be metabolized by the liver. Urinary excretion of oxalate results in lithiasis and nephrocalcinosis leading to a progressive loss of renal function that often requires renal replacement therapy despite medical treatment. Type 1 PH is the most common form and is due to a deficiency in the alanine-glycolate aminotransferase enzyme found in hepatic peroxisomes. Therefore, a liver-kidney simultaneous transplant (LKST) is the definitive treatment for end-stage renal disease (ESRD) patients...
February 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29089105/simultaneous-pancreas-kidney-transplantation-experience-of-the-doce-de-octubre-hospital
#19
Carlos Jiménez-Romero, Alberto Marcacuzco Quinto, Alejandro Manrique Municio, Iago Justo Alonso, Jorge Calvo Pulido, Félix Cambra Molero, Óscar Caso Maestro, Álvaro García-Sesma, Enrique Moreno González
INTRODUCTION: Simultaneous pancreas-kidney transplantation (SPKT) constitutes the therapy of choice for diabetes type1 or type2 associated with end-stage renal disease, because is the only proven method to restore normo-glicemic control in the diabetic patient. METHODS: Retrospective and descriptive study of a series of 175 patients who underwent SPKT from March 1995 to April 2016. We analyze donor and recipient characteristics, perioperative variables and immunosuppression, post-transplant morbi-mortality, patient and graft survival, and risk factors related with patient and graft survival...
October 28, 2017: Cirugía Española
https://www.readbyqxmd.com/read/29081323/cardiovascular-adaptation-to-extrauterine-life-after-intrauterine-growth-restriction
#20
Luciana Rodriguez-Guerineau, Miriam Perez-Cruz, María D Gomez Roig, Francisco J Cambra, Juan Carretero, Fredy Prada, Olga Gómez, Fátima Crispi, Joaquim Bartrons
Introduction The adaptive changes of the foetal heart in intrauterine growth restriction can persist postnatally. Data regarding its consequences for early circulatory adaptation to extrauterine life are scarce. The aim of this study was to assess cardiac morphometry and function in newborns with late-onset intrauterine growth restriction to test the hypothesis that intrauterine growth restriction causes cardiac shape and functional changes at birth. METHODS: A comprehensive echocardiographic study was performed in 25 neonates with intrauterine growth restriction and 25 adequate-for-gestational-age neonates...
October 30, 2017: Cardiology in the Young
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