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Geriatric assessment

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https://www.readbyqxmd.com/read/29665270/european-repository-of-explicit-criteria-of-potentially-inappropriate-medications-in-old-age
#1
Ivana Ivanova, Monique Elseviers, Maarten Wauters, Thierry Christiaens, Robert Vander Stichele
AIM: Lack of electronic assessment of medication lists in electronic health records is a barrier for more generalized use of potentially inappropriate medications (PIM) lists, designed for older adults. The aim was to construct a European repository of explicit criteria on PIM, suitable for electronic assessment. METHODS: PIM description, medication information, clinical information and level of evidence was entered. Criteria with unclear medication specifications were excluded...
April 17, 2018: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/29665258/health-related-quality-of-life-and-fall-risk-associated-with-age-related-body-composition-changes-sarcopenia-obesity-and-sarcopenic-obesity
#2
Zeynel Abidin Öztürk, İbrahim Halil Türkbeyler, Azer Abiyev, Seval Kul, Bahadır Edizer, Funda Datli Yakaryılmaz, Gülçimen Soylu
BACKGROUND: Sarcopenia, obesity, and sarcopenic obesity are various features of the aging process that can cause important health issues. The present study was undertaken to investigate the interrelationship between those body composition changes including their clinical components and the quality of life variables. METHODS: 423 individuals aged 65 years or more were included in this cross-sectional study. Sarcopenia was diagnosed according to The European Working Group on Sarcopenia in Older People criteria...
April 17, 2018: Internal Medicine Journal
https://www.readbyqxmd.com/read/29665066/serotonin-beta-amyloid-and-cognition-in-parkinson-disease
#3
Vikas Kotagal, Cathie Spino, Nicolaas I Bohnen, Robert A Koeppe, Roger L Albin
OBJECTIVE: Serotoninergic neurotransmission may modulate beta-amyloid peptide (Aβ) metabolism through up-regulation of alpha-secretase. Early Parkinson disease (PD) shows variable serotoninergic denervation, which may impact Aβ deposition. METHODS: We conducted three analyses to explore associations between serotoninergic neurotransmission and cerebral Aβ burden in PD. The first was a cross-sectional imaging study of PD subjects (n=23) using the serotoninergic transporter positron emission tomography (PET) ligand [11 C]DASB and amyloid PET Pittsburgh compound B ([11 C]PiB)...
April 17, 2018: Annals of Neurology
https://www.readbyqxmd.com/read/29663061/sizing-lipid-droplets-from-adult-and-geriatric-mouse-liver-tissue-via-nanoparticle-tracking-analysis
#4
Katherine A Muratore, Charles P Najt, Nicholas M Livezey, James Marti, Douglas G Mashek, Edgar A Arriaga
The significance of lipid droplets in lipid metabolism, cell signaling, and regulating longevity is increasingly recognized, yet the lipid droplet's unique properties and architecture make it difficult to size and study using conventional methods. To begin to address this issue, we demonstrate the capabilities of nanoparticle tracking analysis (NTA) for sizing of lipid droplets. NTA was found to be adequate to assess lipid droplet stability over time, indicating that lipid droplet preparations are stable for up to 24 h...
April 17, 2018: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29661649/-overal-cognitive-assessment-in-basque-speaking-people-with-advanced-dementia-validation-to-the-basque-language-of-the-severe-mini-mental-state-examination-smmse-smmse-eus
#5
Cristina Buiza, Javier Yanguas, Amaia Zulaica, Iván Antón, Enrique Arriola, Alvaro García
INTRODUCTION: Adaptation and validation to the Basque language of tests to assess advanced cognitive impairment is a not covered need for Basque-speaking people. The present work shows the validation of the Basque version of the Severe Mini Mental State Examination (SMMSE). MATERIAL AND METHODS: A total of 109 people with advanced dementia (MEC<15) took part in the validation study, and were classified as GDS 5-7 on the Geriatric Depression Scale (GDS). All participants were Spanish-Basque bilingual...
April 13, 2018: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/29659475/frailty-screening-and-a-frailty-pathway-decrease-length-of-stay-loss-of-independence-and-30-day-readmission-rates-in-frail-geriatric-trauma-and-emergency-general-surgery-patients
#6
Kathryn E Engelhardt, Quentin Reuter, Jessica Liu, Jonathan F Bean, Joliette Barnum, Michael B Shapiro, Allison Ambre, Amanda Dunbar, Mara Markzon, Tara Reddy, Christine Schilling, Joseph Posluszny
BACKGROUND: Frail geriatric trauma and emergency general surgery (TEGS) patients have longer lengths of stay (LOS), more readmissions, and higher rates of post-discharge institutionalization than their non-frail counterparts. Despite calls to action by national trauma coalitions, there are few published reports of prospective interventions. The objective of this quality improvement (QI) project was to first develop a frailty screening program, and, then, if frail, implement a novel Frailty Pathway to reduce LOS, 30-day readmissions, and loss of independence (LOI)...
April 13, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29658833/gonadopenia-and-aging-in-men
#7
Sandeep Singh Dhindsa, Michael S Irwig, Kathleen Wyne
OBJECTIVE: The decrease in testosterone levels that occurs with aging has become an important clinical issue both due to the growth of the geriatric population and patient interest in testosterone therapy. The decision to assess for testosterone deficiency and the ability to determine whether the benefits exceed the risks require a comprehensive evaluation of the aging patient. This article is part of a series of papers focused on the endocrinology of aging. This review addresses common issues needed for clinical decision making, including how to interpret test results, differential diagnosis, potential impact of testosterone treatment on insulin resistance and cardiovascular disease, and options for therapy...
April 2018: Endocrine Practice
https://www.readbyqxmd.com/read/29658538/-effectiveness-of-oral-nutritional-supplements-to-prevent-hospital-malnutrition-overview-of-systematic-reviews
#8
Luca Giuseppe Re, Maura Lusignani
. Effectiveness of oral nutritional supplements to prevent hospital malnutrition. Overview of systematic reviews. INTRODUCTION: Although oral nutritional supplements (ONSs) are among most popular interventions to prevent a condition of hospital malnutrition, their real benefits need to be clarified. AIM: To evaluate in adults the effectiveness of ONSs to prevent hospital malnutrition. METHODS: Papers retrieval by querying biomedical databases The Cochrane Library, Medline, Embase, CINAHL...
January 2018: Assistenza Infermieristica e Ricerca: AIR
https://www.readbyqxmd.com/read/29653297/the-efficacy-of-transcranial-random-noise-stimulation-trns-on-mood-may-depend-on-individual-differences-including-age-and-trait-mood
#9
Carys Evans, Michael J Banissy, Rebecca A Charlton
OBJECTIVES: To assess whether changes in brain microstructures associated with ageing and presence of cardiovascular risk factors (CVRF) reduce the efficacy of transcranial electrical stimulation (tES) improving mood in euthymic older adults. METHODS: Using excitatory high-frequency transcranial random noise stimulation (tRNS) over bilateral dorsolateral prefrontal cortex, the effect on mood was assessed in euthymic young adults (YA), older adults (HOA) and older adults with CVRF (OVR)...
March 31, 2018: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29653157/do-depressive-symptoms-affect-balance-in-older-adults-with-mild-cognitive-impairment-results-from-the-gait-and-brain-study
#10
Frederico Pieruccini-Faria, Susan W Muir-Hunter, Manuel Montero-Odasso
BACKGROUND: Mild cognitive impairment (MCI) and depression independently affect balance control in older adults. However, it is uncertain whether depressive symptoms would amplify balance problems in older adults with MCI. AIM: To evaluate if the presence of significant depressive symptoms affects postural sway under somatosensory challenges in a MCI population. METHODS: Eighty two participants (mean of 75.3 ± 6.4 years of age; 46% women) with MCI completed cognitive and balance assessments...
April 10, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29651598/geriatric-assessment-for-older-patients-with-non-small-cell-lung-cancer-daily-practice-of-centers-participating-in-the-nvalt25-eldapt-trial
#11
Elisabeth J M Driessen, Judith G M van Loon, Huub A Maas, Anne-Marie C Dingemans, Maryska L G Janssen-Heijnen
INTRODUCTION: Geriatric assessment (GA) for older patients with lung cancer could provide insight into vulnerability, cognitive impairment, and risk of toxicity. Discontinuation and complications of intensive treatment could potentially be prevented in vulnerable and frail patients. This study aimed to evaluate current clinical practice of GA for older patients with lung cancer in the Netherlands and identify potential hurdles for implementation. METHODS: Pulmonologists and radiation oncologists participating in the NVALT25-ELDAPT trial completed an online questionnaire regarding current practice of GA, added value of GA for treatment decision-making and logistic barriers for patients with non-small cell lung cancer...
April 12, 2018: Lung
https://www.readbyqxmd.com/read/29651322/management-of-frailty-at-individual-level-clinical-management-systematic-literature-review
#12
REVIEW
Gregor Veninšek, Branko Gabrovec
Introduction: To deliver quality management of a frail individual, a clinician should understand the concept of frailty, be aware of its epidemiology and be able to screen for frailty and assess it when it is present, and, finally, to recommend successful interventions. Methodology: A systematic literature search was conducted in the following databases: PubMed, Cochrane, Embase, Cinahl and UpToDate. The criterion in selecting the literature was that articles were published in the period from 2002 to 2017...
June 2018: Zdravstveno Varstvo
https://www.readbyqxmd.com/read/29650688/outcomes-of-elderly-patients-with-advanced-soft-tissue-sarcoma-treated-with-first-line-chemotherapy-a-pooled-analysis-of-12-eortc-soft-tissue-and-bone-sarcoma-group-trials
#13
Eugenie Younger, Saskia Litière, Axel Le Cesne, Olivier Mir, Hans Gelderblom, Antoine Italiano, Sandrine Marreaud, Robin Lewis Jones, Alessandro Gronchi, Winette T A van der Graaf
BACKGROUND: Almost half of patients diagnosed with soft tissue sarcoma (STS) are older than 65 years; however, the outcomes of elderly patients with metastatic disease are not well described. PATIENTS AND METHODS: An elderly cohort of patients aged ≥65 years was extracted from the European Organization for Research and Treatment of Cancer (EORTC) Soft Tissue and Bone Sarcoma Group database of patients treated with first-line chemotherapy for advanced STS within 12 EORTC clinical trials...
April 12, 2018: Oncologist
https://www.readbyqxmd.com/read/29650475/use-of-patient-reported-outcome-measures-in-oral-and-maxillofacial-trauma-surgery-a-review
#14
REVIEW
R Ologunde, N M H McLeod
In the UK, about one person/100/year sustains a facial injury, so trauma surgery accounts for a considerable part of the caseload in oral and maxillofacial surgery (OMFS). Patient-reported outcome measures (PROM) allow for patient-centred assessment of postoperative outcomes, but to our knowledge, most research in OMFS trauma does not currently include them. To investigate their use, we searched Medline to find relevant studies that reported outcomes from inception in January 1879 to August 2016. Those not in the English language and those that did not report operations were excluded...
April 9, 2018: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/29650403/is-age-a-risk-factor-for-depression-among-the-oldest-old-with-cancer
#15
Gil Goldzweig, Lea Baider, Yakir Rottenberg, Elisabeth Andritsch, Jeremy M Jacobs
INTRODUCTION: Age is negatively related to depression among young and middle age patients with cancer. Nevertheless the relationship between age and depression among older patients with cancer is unclear. The goal of the current study is to assess the association of depression with increasing age among older patients with cancer. MATERIALS AND METHODS: Participants were 243 oncology out-patients, aged ≥65, either receiving treatment for active disease or within 6 months of completing treatment for active disease, with a Karnofsky score ≥70...
April 9, 2018: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/29648574/association-of-frailty-with-recovery-from-disability-among-community-dwelling-older-adults-results-from-two-large-u-s-cohorts
#16
Chenkai Wu, Dae H Kim, Qian-Li Xue, David S H Lee, Ravi Varadhan, Michelle C Odden
Background: Disability in activities of daily living (ADLs) is a dynamic process and transitions among different disability states are common. However, little is known about factors affecting recovery from disability. We examined the association between frailty and recovery from disability among non-disabled community-dwelling elders. Methods: We studied 1023 adults from the Cardiovascular Health Study (CHS) and 685 adults from the Health and Retirement Study (HRS), who were ≥65 years and had incident disability, defined as having difficulty in ≥1 ADL (dressing, eating, toileting, bathing, transferring, walking across a room)...
April 10, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29643802/the-beneficial-effects-of-cognitive-training-with-simple-calculation-and-reading-aloud-scra-in-the-elderly-postoperative-population-a-pilot-randomized-controlled-trial
#17
Kay Kulason, Rui Nouchi, Yasushi Hoshikawa, Masafumi Noda, Yoshinori Okada, Ryuta Kawashima
Background: There has been little research conducted regarding cognitive treatments for the elderly postsurgical population. Patients aged ≥60 years have an increased risk of postoperative cognitive decline, a condition in which cognitive functions are negatively affected. This cognitive decline can lead to a decline in quality of life. In order to maintain a high quality of life, the elderly postsurgical population may benefit from treatment to maintain and/or improve their cognitive functions. This pilot study investigates the effect of simple calculation and reading aloud (SCRA) cognitive training in elderly Japanese postsurgical patients...
2018: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29643004/association-between-mediterranean-diet-and-hand-grip-strength-in-older-adult-women
#18
Luigi Barrea, Giovanna Muscogiuri, Carolina Di Somma, Giovanni Tramontano, Vincenzo De Luca, Maddalena Illario, Annamaria Colao, Silvia Savastano
BACKGROUND & AIMS: Mediterranean Diet (MD) is an eating pattern associated with multiple healthy benefits, including the conservation of skeletal muscle. Frailty is a major geriatric syndrome characterized by low muscle strength. The Hand Grip Strength (HGS) is the most frequently used indicator of muscle functional capacity for clinical purposes. The association between the adherence to the MD and HGS in elderly has not yet fully investigated. The goal of this study was to examine the association between the adherence to the MD and HGS in a not hospitalized elderly who participated in the project PERsonalised ict Supported Services for Independent Living and Active Ageing (PERSSILAA)...
April 3, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29630004/characteristics-of-older-adults-who-are-unable-to-perform-a-floor-transfer-considerations-for-clinical-decision-making
#19
Gunay Ardali, Rebecca A States, Lori T Brody, Ellen M Godwin
BACKGROUND AND PURPOSE: The ability to get down and up from the floor or to perform a floor transfer (FT) is a vital and useful skill for older adults at risk of falling. Little is known about the health-related factors that separate older adults who can perform FT independently from those who cannot. Therefore, the specific aims of this cross-sectional study are to (1) describe and compare health-related factors among older adults who were independent, assisted, or dependent in FT performance; and (2) establish the parallel reliability between self-reported and actual performance of FT...
April 6, 2018: Journal of Geriatric Physical Therapy
https://www.readbyqxmd.com/read/29628887/disease-specific-aspects-of-malnutrition-in-neurogeriatric-patients
#20
REVIEW
Tino Prell, Caroline Perner
Malnutrition in elderly patients is a common condition. Nevertheless, there is evidence on specific risk factors and problems of malnutrition in geriatric patients with neurological diseases. In this review, we summarize recent knowledge on malnutrition in different neurological diseases with a focus on elderly patients. This overview also provides strategies for a more specific and profound assessment of neurogeriatric patients to improve identification and treatment of malnutrition. Early and consequent treatment of malnutrition can lead to a decreased progression of the neurological disease and to a better quality of life in geriatric patients...
2018: Frontiers in Aging Neuroscience
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