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https://www.readbyqxmd.com/read/29160212/stellate-erosion-the-dermoscopic-nikolsky-sign
#1
Zoe Apalla, Aimilios Lallas, Elena Sotiriou, Elizabeth Lazaridou, Efstratios Vakirlis, Dimitrios Ioannides
No abstract text is available yet for this article.
November 21, 2017: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/29160090/two-consecutive-cases-of-persistent-stapedial-artery-managed-with-a-carbon-dioxide-laser
#2
Shawn M Stevens, Zoe A Walters, Kareem Tawfik, Ravi N Samy
OBJECTIVE: (1) Discuss the presentation and management of persistent stapedial artery (PSA) discovered incidentally during cholesteatoma surgery. (2) Review use of carbon dioxide (CO2) laser for treatment of PSA in the setting of chronic ear disease. PATIENTS: Two consecutive patients with PSA and primary acquired cholesteatoma. INTERVENTION(S): Tympanomastoidectomy using a canal wall reconstruction technique. MAIN OUTCOME MEASURE(S): Surgical healing, collateral damage to surrounding anatomy, and postoperative hearing...
November 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/29155828/role-of-co-repressor-genomic-landscapes-in-shaping-the-notch-response
#3
Stephen K K Chan, Gustavo Cerda-Moya, Robert Stojnic, Kat Millen, Bettina Fischer, Silvie Fexova, Lenka Skalska, Maria Gomez-Lamarca, Zoe Pillidge, Steven Russell, Sarah J Bray
Repressors are frequently deployed to limit the transcriptional response to signalling pathways. For example, several co-repressors interact directly with the DNA-binding protein CSL and are proposed to keep target genes silenced in the absence of Notch activity. However, the scope of their contributions remains unclear. To investigate co-repressor activity in the context of this well defined signalling pathway, we have analysed the genome-wide binding profile of the best-characterized CSL co-repressor in Drosophila, Hairless, and of a second CSL interacting repressor, SMRTER...
November 20, 2017: PLoS Genetics
https://www.readbyqxmd.com/read/29152364/a-2-1-co-crystal-of-3-5-di-bromo-4-cyano-benzoic-acid-and-anthracene
#4
Wayland E Noland, Janel L Rieger, Zoe H Tu, Kenneth J Tritch
The title co-crystal, C8H3Br2NO2·0.5C14H10, was self-assembled from a 2:1 mixture of the components in slowly evaporating di-chloro-methane. The mol-ecules adopt a sheet structure parallel to (1-12) in which carb-oxy hydrogen-bonded dimers and anthracene mol-ecules stagger in both dimensions. Within the sheets, six individual cyano acid mol-ecules surround each anthracene mol-ecule. Cyano acid mol-ecules form one of the two possible R2(2)(10) rings between neighboring cyano and bromo groups. Compared to the di-chloro analog [Britton (2012 ▸)...
November 1, 2017: Acta Crystallographica. Section E, Crystallographic Communications
https://www.readbyqxmd.com/read/29145838/mri-characteristics-for-phantom-scratching-in-canine-syringomyelia
#5
Zoe R Nalborczyk, Angus K McFadyen, Jelena Jovanovik, Anna Tauro, Colin J Driver, Noel Fitzpatrick, Susan P Knower, Clare Rusbridge
BACKGROUND: A classic sign of canine syringomyelia (SM) is scratching towards one shoulder. Using magnetic resonance imaging (MRI) we investigate the spinal cord lesion relating to this phenomenon which has characteristics similar to fictive scratch secondary to spinal cord transection. Medical records were searched for Cavalier King Charles spaniels with a clinical and MRI diagnosis of symptomatic SM associated with Chiari-like malformation (CM). The cohort was divided into SM with phantom scratching (19 dogs) and SM but no phantom scratching (18 dogs)...
November 16, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29145764/plasma-corticosterone-epinephrine-and-norepinephrine-levels-increase-during-administration-of-nitrous-oxide-in-rats
#6
Salwa Al-Noori, Andreas Cimpan, Zoe Maltzer, Karl J Kaiyala, Douglas S Ramsay
Nitrous oxide (N2O) is a gaseous drug with abuse potential. Despite its common clinical use, little is known about whether N2O administration activates the HPA axis and/or the sympathetic adrenomedullary system. The goal of this study was to determine whether 60% N2O alters plasma concentrations of corticosterone (CORT), epinephrine (EPI), and norepinephrine (NE) in male Long-Evans rats. A gas-tight swivel assembly in the lid of a gas administration chamber allowed the remote collection of blood samples from an indwelling jugular vein catheter at four time-points: baseline and at 30, 60, and 120 min during a two-hour administration of 60% N2O...
November 16, 2017: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29145469/development-of-visual-cortical-function-in-infant-macaques-a-bold-fmri-study
#7
Tom J Van Grootel, Alan Meeson, Matthias H J Munk, Zoe Kourtzi, J Anthony Movshon, Nikos K Logothetis, Lynne Kiorpes
Functional brain development is not well understood. In the visual system, neurophysiological studies in nonhuman primates show quite mature neuronal properties near birth although visual function is itself quite immature and continues to develop over many months or years after birth. Our goal was to assess the relative development of two main visual processing streams, dorsal and ventral, using BOLD fMRI in an attempt to understand the global mechanisms that support the maturation of visual behavior. Seven infant macaque monkeys (Macaca mulatta) were repeatedly scanned, while anesthetized, over an age range of 102 to 1431 days...
2017: PloS One
https://www.readbyqxmd.com/read/29140763/zoe-d-peterson-editor-the-wiley-handbook-of-sex-therapy-2017-john-wiley-and-sons-ltd-west-sussex-uk-514-pages-129-03-hb-130-50-kindle
#8
Pega Ren
No abstract text is available yet for this article.
November 15, 2017: Journal of Sex & Marital Therapy
https://www.readbyqxmd.com/read/29140476/identification-of-multiple-genomic-dna-sequences-which-form-i-motif-structures-at-neutral-ph
#9
Elisé P Wright, Julian L Huppert, Zöe A E Waller
No abstract text is available yet for this article.
November 13, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29138738/spatial-distribution-and-trends-of-waterborne-diseases-in-tashkent-province
#10
Veluswami Saravanan Subramanian, Min Jung Cho, Siwei Zoe Tan, Dilorom Fayzieva, Christian Sebaly
Introduction: The cumulative effect of limited investment in public water systems, inadequate public health infrastructure, and gaps in infectious disease prevention increased the incidence of waterborne diseases in Uzbekistan. The objectives of this study were: (1) to spatially analyze the distribution of the diseases in Tashkent Province, (2) to identify the intensity of spatial trends in the province, (3) to identify urban-rural characteristics of the disease distribution, and (4) to identify the differences in disease incidence between pediatric and adult populations of the province...
2017: Central Asian Journal of Global Health
https://www.readbyqxmd.com/read/29133322/factors-contributing-to-medicine-related-problems-in-adult-patients-with-diabetes-and-or-cardiovascular-diseases-in-saudi-arabia-a-qualitative-study
#11
Abdullah Mahdi Al Hamid, Maisoon Ghaleb, Hisham Aljadhey, Zoe Aslanpour
OBJECTIVES: To investigate the factors contributing to medicine-related problems (MRPs) among patients with cardiovascular diseases (CVDs) and/or diabetes in Saudi Arabia. DESIGN: Qualitative semistructured interviews were conducted. Interviews were audio recorded then transcribed into Microsoft Word. The transcribed interviews were then imported into the qualitative analysis software NVivo where thematic analysis was applied. Thematic synthesis was achieved by coding and developing subthemes/themes from the findings of the interviews...
November 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/29129942/priorities-for-research-in-soil-ecology
#12
Nico Eisenhauer, Pedro M Antunes, Alison E Bennett, Klaus Birkhofer, Andrew Bissett, Matthew A Bowker, Tancredi Caruso, Baodong Chen, David C Coleman, Wietse de Boer, Peter de Ruiter, Thomas H DeLuca, Francesco Frati, Bryan S Griffiths, Miranda M Hart, Stephan Hättenschwiler, Jari Haimi, Michael Heethoff, Nobuhiro Kaneko, Laura C Kelly, Hans Petter Leinaas, Zoë Lindo, Catriona Macdonald, Matthias C Rillig, Liliane Ruess, Stefan Scheu, Olaf Schmidt, Timothy R Seastedt, Nico M van Straalen, Alexei V Tiunov, Martin Zimmer, Jeff R Powell
The ecological interactions that occur in and with soil are of consequence in many ecosystems on the planet. These interactions provide numerous essential ecosystem services, and the sustainable management of soils has attracted increasing scientific and public attention. Although soil ecology emerged as an independent field of research many decades ago, and we have gained important insights into the functioning of soils, there still are fundamental aspects that need to be better understood to ensure that the ecosystem services that soils provide are not lost and that soils can be used in a sustainable way...
July 2017: Pedobiologia
https://www.readbyqxmd.com/read/29127717/salivary-uric-acid-and-c-reactive-protein-associations-with-hypertensionin-midwestern-latino-preadolescents-and-their-parents
#13
Blake L Jones, Salma Elwazeer, Zoe E Taylor
Latino families face increased risk for hypertension. Serum-based uric acid and C-reactive protein have been linked to hypertension. However, a paucity of salivary biomarker data exists in this area for Latino families. Using salivary biomarkers enables less invasive options for biomedical and biosocial research, which is especially important among vulnerable populations facing increased health disparities. This study examined the associations between salivary uric (sUA) acid, salivary C-reactive protein (sCRP), and hypertension among 151 participants (57 children, 57 mothers, 37 fathers) from 57 Midwestern Latino families...
November 11, 2017: Developmental Psychobiology
https://www.readbyqxmd.com/read/29126998/high-runner-mice-have-reduced-incentive-salience-for-a-sweet-taste-reward-when-housed-with-wheel-access
#14
Zoe Thompson, Erik M Kolb, Theodore Garland
To explore reward substitution in the context of voluntary exercise, female mice from four replicate high-runner (HR) lines (bred for wheel running) and four non-selected control (C) lines were given simultaneous access to wheels and palatable solutions as competing rewards (two doses of saccharin [0.1, 0.2% w/v]; two doses of common artificial sweetener blends containing saccharin [Sweet 'N Low(®): 0.1, 0.2% w/v], aspartame [Equal(®): 0.04, 0.08% w/v], or sucralose [Splenda(®): 0.08, 0.16% w/v]; or two doses of sucrose [3...
November 7, 2017: Behavioural Processes
https://www.readbyqxmd.com/read/29119352/using-physics-based-pose-predictions-and-free-energy-perturbation-calculations-to-predict-binding-poses-and-relative-binding-affinities-for-fxr-ligands-in-the-d3r-grand-challenge-2
#15
Christina Athanasiou, Sofia Vasilakaki, Dimitris Dellis, Zoe Cournia
Computer-aided drug design has become an integral part of drug discovery and development in the pharmaceutical and biotechnology industry, and is nowadays extensively used in the lead identification and lead optimization phases. The drug design data resource (D3R) organizes challenges against blinded experimental data to prospectively test computational methodologies as an opportunity for improved methods and algorithms to emerge. We participated in Grand Challenge 2 to predict the crystallographic poses of 36 Farnesoid X Receptor (FXR)-bound ligands and the relative binding affinities for two designated subsets of 18 and 15 FXR-bound ligands...
November 8, 2017: Journal of Computer-aided Molecular Design
https://www.readbyqxmd.com/read/29117796/effects-of-varenicline-therapy-in-combination-with-advanced-behavioral-support-on-smoking-cessation-and-quality-of-life-in-inpatients-with-acute-exacerbation-of-copd-bronchial-asthma-or-community-acquired-pneumonia-a-prospective-open-label-preference-based
#16
Alexios Politis, Vasileios Ioannidis, Konstantinos I Gourgoulianis, Zoe Daniil, Chrissi Hatzoglou
Quitting smoking is the most important element in the therapeutic management of chronic respiratory diseases. Combining pharmacotherapy with behavioral support increases smoking cessation success rates. In addition, hospitalized smokers have increased motivation to quit. We investigated the efficacy on smoking cessation, of varenicline in combination with behavioral support, in smokers hospitalized due to (a) acute exacerbation of chronic obstructive pulmonary disease (COPD), or (b) bronchial asthma attack, or (c) community-acquired pneumonia (CAP)...
January 1, 2017: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/29117752/the-criminogenic-and-noncriminogenic-treatment-needs-of-intimate-partner-violence-offenders
#17
N Zoe Hilton, Dana L Radatz
The criminogenic needs of general offenders have been empirically studied, but the criminogenic treatment needs of intimate partner violence (IPV) offenders, or how they compare with other violent or nonviolent offenders, have not been as thoroughly explored. Therefore, we examined and compared the criminogenic and noncriminogenic needs of 99 IPV offenders, 233 non-IPV violent offenders, and 103 nonviolent offenders, all of whom were men who had undergone institutional forensic assessment. Results indicated that IPV offenders had more treatment needs than the other two offender groups, including the Central Eight criminogenic needs...
November 1, 2017: International Journal of Offender Therapy and Comparative Criminology
https://www.readbyqxmd.com/read/29111770/contemporary-trends-in-cardiogenic-shock-incidence-intra-aortic-balloon-pump-utilisation-and-outcomes-from-the-london-heart-attack-group
#18
Krishnaraj S Rathod, Sudheer Koganti, M Bilal Iqbal, Ajay K Jain, Sundeep S Kalra, Zoe Astroulakis, Pitt Lim, Roby Rakhit, Miles C Dalby, Tim Lockie, Iqbal S Malik, Charles J Knight, Mark Whitbread, Anthony Mathur, Simon Redwood, Philip A MacCarthy, Alexander Sirker, Constantinos O'Mahony, Andrew Wragg, Daniel A Jones
BACKGROUND: Cardiogenic shock remains a major cause of morbidity and mortality in patients with ST-segment elevation myocardial infarction. We aimed to assess the current trends in cardiogenic shock management, looking specifically at the incidence, use of intra-aortic balloon pump therapy and outcomes in patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention. METHODS AND RESULTS: We undertook an observational cohort study of 21,210 ST-segment elevation myocardial infarction patients treated between 2005-2015 at the eight Heart Attack Centres in London, UK...
November 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29111478/verbal-working-memory-and-functional-large-scale-networks-in-schizophrenia
#19
Maria R Dauvermann, Thomas Wj Moorhead, Andrew R Watson, Barbara Duff, Liana Romaniuk, Jeremy Hall, Neil Roberts, Graham L Lee, Zoë A Hughes, Nicholas J Brandon, Brandon Whitcher, Douglas Hr Blackwood, Andrew M McIntosh, Stephen M Lawrie
The aim of this study was to test whether bilinear and nonlinear effective connectivity (EC) measures of working memory fMRI data can differentiate between patients with schizophrenia (SZ) and healthy controls (HC). We applied bilinear and nonlinear Dynamic Causal Modeling (DCM) for the analysis of verbal working memory in 16 SZ and 21 HC. The connection strengths with nonlinear modulation between the dorsolateral prefrontal cortex (DLPFC) and the ventral tegmental area/substantia nigra (VTA/SN) were evaluated...
October 23, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29111456/viruses-associated-with-antarctic-wildlife-from-serology-based-detection-to-identification-of-genomes-using-high-throughput-sequencing
#20
REVIEW
Zoe E Smeele, David G Ainley, Arvind Varsani
The Antarctic, sub-Antarctic islands and surrounding sea-ice provide a unique environment for the existence of organisms. Nonetheless, birds and seals of a variety of species inhabit them, particularly during their breeding seasons. Early research on Antarctic wildlife health, using serology-based assays, showed exposure to viruses in the families Birnaviridae, Flaviviridae, Herpesviridae, Orthomyxoviridae and Paramyxoviridae circulating in seals (Phocidae), penguins (Spheniscidae), petrels (Procellariidae) and skuas (Stercorariidae)...
October 27, 2017: Virus Research
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