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chronic low back pain

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https://www.readbyqxmd.com/read/28814894/startle-modulation-by-heat-pain-with-varying-threat-levels-in-chronic-pain-patients-and-pain-free-controls
#1
C Horn-Hofmann, D Wolf, S Wolff, M Heesen, K Knippenberg-Bigge, P M Lang, S Lautenbacher
BACKGROUND: Empirical evidence suggests that affective responses to pain are changed in chronic pain. The investigation of startle responses to pain might contribute to clarifying whether such alterations also expand to motivational defensive reactions. We aimed at comparing startle responses to tonic heat pain with high threat (HT) or low threat (LT) in patients with chronic musculoskeletal pain and controls. As pain-related anxiety and catastrophizing are typically elevated in chronic pain, we expected to find stronger startle responses in patients specifically under experimental HT...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28814385/gabapentinoids-should-not-be-used-for-chronic-low-back-pain-meta-analysis-concludes
#2
Jacqui Wise
No abstract text is available yet for this article.
August 16, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28809936/benefits-and-safety-of-gabapentinoids-in-chronic-low-back-pain-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#3
Harsha Shanthanna, Ian Gilron, Manikandan Rajarathinam, Rizq AlAmri, Sriganesh Kamath, Lehana Thabane, Philip J Devereaux, Mohit Bhandari
BACKGROUND AND OBJECTIVE: Chronic Low Back Pain (CLBP) is very common, with a lifetime prevalence between 51% and 80%. In majority, it is nonspecific in nature and multifactorial in etiology. Pregabalin (PG) and Gabapentin (GB) are gabapentinoids that have demonstrated benefit in neuropathic pain conditions. Despite no clear rationale, they are increasingly used for nonspecific CLBP. They necessitate prolonged use and are associated with adverse effects and increased cost. Recent guidelines from the National Health Service (NHS), England, expressed concerns on their off-label use, in addition to the risk of misuse...
August 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28807894/advances-in-the-diagnosis-and-management-of-neck-pain
#4
REVIEW
Steven P Cohen, W Michael Hooten
Neck pain imposes a considerable personal and socioeconomic burden-it is one of the top five chronic pain conditions in terms of prevalence and years lost to disability-yet it receives a fraction of the research funding given to low back pain. Although most acute episodes resolve spontaneously, more than a third of affected people still have low grade symptoms or recurrences more than one year later, with genetics and psychosocial factors being risk factors for persistence. Nearly half of people with chronic neck pain have mixed neuropathic-nociceptive symptoms or predominantly neuropathic symptoms...
August 14, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28807742/a-cost-utility-analysis-of-dynesys-dynamic-stabilization-versus-instrumented-fusion-for-the-treatment-of-degenerative-lumbar-spine-diseases
#5
Kan Liu, Wei Sun, Qiang Lu, Jiying Chen, Jiaguang Tang
BACKGROUND: Symptomatic chronic low back and leg pain resulting from lumbar spine degenerative disorders is highly prevalent in China, and for some patients, surgery is the final option for improvement. Several techniques for spinal non-fusion have been introduced to reduce the side-effects of fusion methods and hasten postoperative recovery. In this study, the authors have evaluated the cost-effectiveness of Dynesys posterior dynamic stabilization system (DY) compared with lumbar fusion techniques in the treatment of single-level degenerative lumbar spinal conditions...
August 11, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28804504/efficacy-of-auricular-acupressure-for-chronic-low-back-pain-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#6
REVIEW
Li-Hua Yang, Pei-Bei Duan, Qing-Mei Hou, Shi-Zheng Du, Jin-Fang Sun, Si-Juan Mei, Xiao-Qing Wang
OBJECTIVES: To identify the efficacy of auricular acupressure on pain and disability for chronic LBP by systematic review. METHODS: A search of randomized controlled trials was conducted in four English medical electronic databases and three Chinese databases. Two reviewers independently retrieved related studies, assessed the methodological quality, and extracted data with a standardized data form. Meta-analyses were performed using all time-points meta-analysis...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28803704/effectiveness-of-graded-activity-versus-physiotherapy-in-patients-with-chronic-nonspecific-low-back-pain-midterm-follow-up-results-of-a-randomized-controlled-trial
#7
Maurício Oliveira Magalhães, Josielli Comachio, Paulo Henrique Ferreira, Evangelos Pappas, Amélia Pasqual Marques
BACKGROUND: Low back pain (LBP) is a major health and economic problem worldwide. Graded activity and physiotherapy are commonly used interventions for nonspecific low back pain. However, there is currently little evidence to support the use of one intervention over the other in the medium-term. OBJECTIVE: To compare the effectiveness of graded activity exercises to physiotherapy-based exercises at mid-term (three and six months' post intervention) in patients with chronic nonspecific LBP...
July 12, 2017: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/28800302/the-effect-of-pain-severity-on-postural-stability-and-dynamic-limits-of-stability-in-chronic-low-back-pain
#8
Elsadat Saad Soliman, Tamer Mohamed Shousha, Mohamed Salaheldien Alayat
BACKGROUND: Deficits of dynamic balance in chronic low back pain patients have been reported by different studies in terms of impaired postural control. However, they excluded the degree of pain as a determinant affecting dynamic balance. OBJECTIVE: To evaluate the effect of pain intensity on dynamic balance control in terms of postural stability indices (PSIs) and limits of stability (LOS) in chronic LBP patients. METHODS: Sixty subjects (38 men, 22 women) participated in the current study, 45 patients with chronic LBP were selected randomly and served as the chronic LBP group while 15 healthy subjects served as the asymptomatic group (AS)...
July 31, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28798688/establishment-and-characterization-of-a-novel-rat-model-of-mechanical-low-back-pain-using-behavioral-pharmacologic-and-histologic-methods
#9
Arjun Muralidharan, Thomas S W Park, John T Mackie, Luiz G S Gimenez, Andy Kuo, Janet R Nicholson, Laura Corradini, Maree T Smith
Chronic low back pain (LBP), the leading cause of disability globally, is notoriously difficult to treat. Most rodent models of LBP mimic lumbar radicular pain rather than mechanical LBP. Here, we describe establishment of a new rat model of mechanical LBP that is devoid of a neuropathic component. Groups of adult male Sprague Dawley rats were anesthetized and their lumbar L4/L5 and L5/L6 intervertebral disks (IVDs) were punctured (0.5 mm outer diameter, 2mm-deep) 5 (LPB-5X), or 10 (LBP-10X) times per disk...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28797134/looking-beyond-the-intervertebral-disc-the-need-for-behavioral-assays-in-models-of-discogenic-pain
#10
REVIEW
Grace E Mosley, Thomas W Evashwick-Rogler, Alon Lai, James C Iatridis
Orthopedic research into chronic discogenic back pain has commonly focused on aging- and degeneration-related changes in intervertebral disc structure, biomechanics, and biology. However, the primary spine-related reason for physician office visits is pain. The ambiguous nature of the human condition of discogenic low back pain motivates the use of animal models to better understand the pathophysiology. Discogenic back pain models must consider both emergent behavioral changes following pain induction and changes in the nervous system that mediate such behavior...
August 10, 2017: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/28796117/spouse-criticism-and-hostility-during-marital-interaction-effects-on-pain-intensity-and-behaviors-among-individuals-with-chronic-low-back-pain
#11
John W Burns, Kristina M Post, David A Smith, Laura S Porter, Asokumar Buvanendran, Anne Marie Fras, Francis J Keefe
Individuals with chronic pain may experience negative responses from spouse, family and friends. Responses such as overt criticism and hostility may be associated with worsening pain and function for chronic pain sufferers. We used a laboratory procedure to evaluate whether variability in spouse criticism/hostility exhibited toward chronic low back pain (CLBP) patients during a conflictual discussion predicted variability in patient pain and function during a subsequent pain-induction task. CLBP patients (n=71) and their spouses (n=71) participated in a 10-minute discussion followed by the patient undergoing a 10-minute structured pain behavior task (SPBT)...
August 8, 2017: Pain
https://www.readbyqxmd.com/read/28795014/evaluation-and-management-of-lower-back-pain-in-young-athletes
#12
REVIEW
Dilip R Patel, Elizabeth Kinsella
Lower back pain in young athletes is a common problem. The prevalence of back pain from different causes in adolescent age group is between 20% and 30%. However, the incidence of low back pain in young athletes varies widely in different sports. Overuse injuries are the most common cause of low back pain in young athletes. In case of overuse injuries, the cause and effect relationship between back pain and specific condition is often difficult to establish. In adolescent athletes, the most common underlying identified cause of low back pain is lumbar spondylolysis...
July 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28795010/evaluation-and-management-of-knee-pain-in-young-athletes-overuse-injuries-of-the-knee
#13
REVIEW
Dilip R Patel, Ana Villalobos
Recurrent or chronic activity related knee pain is common in young athletes. Numerous intrinsic conditions affecting the knee can cause such pain. In addition, knee pain can be referred pain from low back, hip or pelvic pathology. The most common cause of knee pain in young athletes is patellofemoral pain syndrome, or more appropriately termed idiopathic anterior knee pain. Although, numerous anatomical and biomechanical factors have been postulated to contribute the knee pain in young athletes, the most common underlying reason is overuse injury...
July 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28789781/training-peers-to-support-older-people-with-chronic-low-back-pain-following-physiotherapy-discharge-a-feasibility-study
#14
Kay Cooper, Llinos M Jehu, Susan Klein, Blair H Smith, Patricia Schofield
OBJECTIVE: To determine the feasibility and acceptability of a training programme for peer volunteers to support older adults with chronic low back pain (CLBP) following discharge from physiotherapy. DESIGN: Feasibility study. SETTING: Community-based. PARTICIPANTS: 17 adults (4 male, 13 female) with CLBP or experience of supporting someone with CLBP enrolled and 12 (2 male, 10 female) completed the volunteer training...
July 13, 2017: Physiotherapy
https://www.readbyqxmd.com/read/28775180/sick-leave-and-medication-use-in-pregnancy-a-european-web-based-study
#15
Bich Thuy Truong, Angela Lupattelli, Petter Kristensen, Hedvig Nordeng
BACKGROUND AND OBJECTIVE: A comparison of sick leave in pregnancy between countries is difficult as most studies have been conducted in single countries in Scandinavia. The objective of this study was to explore patterns of and reasons for sick leave during pregnancy on a multinational level, focusing on medication use but also differences in sick leave policies. DESIGN AND SETTING: Cross-sectional, web-based study in 12 European countries from October 2011 to February 2012...
August 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/28771864/back-school-programme-for-nurses-has-reduced-low-back-pain-levels-a-randomized-controlled-trial
#16
M Járomi, A Kukla, B Szilágyi, Á Ugron, V Kovácsné Bobály, A Makai, P Linek, P Ács, E Leidecker
BACKGROUND: Millions of nurses around the world suffer from occupational-related chronic non-specific low back pain (cnsLBP). Generally, LBP in nurses is a result of increased pressure on the spine, and can be associated with improperly conducted patient lifting techniques. AIMS AND OBJECTIVES: The purposes of the study were:1) to examine patient lifting techniques used by nurses; and 2) to evaluate an effectiveness of the Spine Care for Nurses programme in cnsLBP reduction and the execution of proper patient lifting techniques...
August 3, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28770974/back-schools-for-chronic-non-specific-low-back-pain
#17
REVIEW
Patrícia Parreira, Martijn W Heymans, Maurits W van Tulder, Rosmin Esmail, Bart W Koes, Nolwenn Poquet, Chung-Wei Christine Lin, Christopher G Maher
BACKGROUND: Many people with low back pain (LBP) become frequent users of healthcare services in their attempt to find treatments that minimise the severity of their symptoms. Back School consists of a therapeutic programme given to groups of people that includes both education and exercise. However, the content of Back School has changed over time and appears to vary widely today. This review is an update of a Cochrane review of randomised controlled trials (RCTs) evaluating the effectiveness of Back School...
August 3, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28769588/duloxetine-60-mg-for-chronic-low-back-pain-post-hoc-responder-analysis-of-double-blind-placebo-controlled-trials
#18
Levent Alev, Shinji Fujikoshi, Aki Yoshikawa, Hiroyuki Enomoto, Mitsuhiro Ishida, Toshinaga Tsuji, Kei Ogawa, Shinichi Konno
INTRODUCTION: Duloxetine has demonstrated efficacy in chronic low back pain (CLBP). We examined the predictors of response to duloxetine for CLBP. PATIENTS AND METHODS: This was a post hoc analysis of pooled data from 4 double-blind, ran-domized, placebo-controlled trials of duloxetine (60 mg/day for 12-14 weeks) in adult patients with CLBP. Primary outcome was proportion of patients with ≥30% reduction in Brief Pain Inventory (BPI) average pain ("pain reduction") at 12-14 weeks...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28767621/the-ute-disc-sign-on-mri-a-novel-imaging-biomarker-associated-with-degenerative-spine-changes-low-back-pain-and-disability
#19
Henry Pang, Cora Bow, Jason Pui Yin Cheung, Uruj Zehra, Arijitt Borthakur, Jaro Karppinen, Nozomu Inoue, Hai-Qiang Wang, Keith D K Luk, Kenneth M C Cheung, Dino Samartzis
STUDY DESIGN: Cross-sectional. OBJECTIVE: To assess the distribution of the ultra-short time-to-echo (UTE) Disc Sign (UDS).and its association with disc degeneration, other MRI phenotypes, pain and disability profiles. SUMMARY OF BACKGROUND DATA: Disc degeneration has been conventionally assessed by T2-weighted (T2W) signal intensity on MRI; however, its clinical utility has been questionable. UTE MRI assesses short T2 components. The authors have identified a new imaging biomarker on UTE - the UDS...
August 1, 2017: Spine
https://www.readbyqxmd.com/read/28767595/the-comparison-of-measurement-between-ultrasound-and-computed-tomography-for-abnormal-degenerative-facet-joints-a-strobe-compliant-article
#20
Wen Shi, Dan Tian, Da Liu, Jing Yin, Ying Huang
Besides the study on examining facet joints of lumbar spine by ultrasound in normal population, there has not been any related report about examining normal facet joints of lumbar spine by ultrasound so far. This study was aimed to explore the feasibility of ultrasound assessment of lumber spine facet joints by comparing ultrasound measure values of normal and degenerative lumber spine facet joints, and by comparing measure values of ultrasound and computed tomography (CT) of degenerative lumber spine facet joints...
August 2017: Medicine (Baltimore)
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