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Micrographic surgery

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https://www.readbyqxmd.com/read/28433227/nonsurgical-therapies-for-basal-cell-carcinoma-a-review
#1
S Ariza, S Espinosa, M Naranjo
Basal cell carcinoma (BCC) is the most prevalent malignant tumor in humans and the local destruction of tissue that can result from excision has a significant impact on well-being. Treating BCC is costly for health care systems given the high incidence of this tumor, especially in older patients. Standard treatment involves either resection with histologic assessment of margins or Mohs micrographic surgery. Surgery is sometimes contraindicated, however, due to the presence of significant comorbidity or high cosmetic expectations...
April 19, 2017: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/28411790/the-use-of-gentian-violet-2-solution-to-identify-holes-in-the-deep-margin-of-tissue-excised-during-mohs-micrographic-surgery
#2
Thuzar M Shin, Jeremy R Etzkorn, Joseph F Sobanko, Waqas R Shaikh, Stephen J Kovach, Christopher J Miller
No abstract text is available yet for this article.
May 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28406864/multistep-approach-for-improved-aesthetic-and-functional-outcomes-for-lower-extremity-wound-closure-after-mohs-micrographic-surgery
#3
Elizabeth Kiwanuka, Antonio P Cruz
BACKGROUND: Lower extremity wounds present a major clinical challenge. OBJECTIVE: This paper introduces a new multistep approach for improved aesthetic and functional outcome for lower extremity wound closure after Mohs micrographic surgery. PATIENTS AND METHODS: In this prospective case series, 12 consecutive patients undergoing Mohs micrographic surgery for cutaneous malignancies of the lower extremities underwent closure assisted by elastic bandages, proper positioning with 45° flexion of the knee, buried vertical mattress sutures, and careful eversion, using a premium angled stapler...
April 11, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28401602/piloting-a-new-patient-related-outcome-tool-to-assess-cosmetic-outcome-in-mohs-micrographic-surgery
#4
A A Yong, V Tan, E Craythorne, R Mallipeddi
Poor cosmetic outcome is associated with significant negative impact on quality of life (QOL).(1) The degree of psychosocial distress may be more correlated with patient perception rather than objective scar severity. The patient's personal assessment is the primary influence on psychosocial morbidity.(1) Therefore, patient-reported outcome (PRO) instruments are valuable in assessing cosmetic outcome and impact on QOL. This article is protected by copyright. All rights reserved.
April 12, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28397683/-mohs-surgery-for-basal-cell-carcinoma
#5
Martin Glud, Silje Haukali Omland, John Paoli, Robert Gniadecki
Micrographic surgery is currently the only technique which ensures complete removal of basal cell carcinomas. The major limitation is the high set-up cost, which is particularly connected with specialized training of surgeons, technicians and the set-up of a histology facility for frozen tissue sectioning and staining. In the long run, however, the cost of Mohs surgery per patient does not exceed that of conventional surgery. The technique is very safe and has multiple advantages over any other treatment modality...
February 6, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28394861/endocrine-mucin-producing-sweat-gland-carcinoma-treated-with-mohs-micrographic-surgery
#6
Brian L Scott, Cynthia O Anyanwu, Travis Vandergriff, Rajiv I Nijhawan
No abstract text is available yet for this article.
April 6, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28388346/malignant-fibrous-histiocytoma-masquerading-as-pyogenic-granuloma
#7
Pavindran Gounder, Minh Lam, Carl Vinciullo, Jean-Louis de Sousa
A 68-year-old gentleman presented with a lesion that resembled a pyogenic granuloma in his inferior fornix. The lesion was excised and biopsy demonstrated a proliferation of malignant spindle cells. Three weeks following initial excision, the lesion recurred and was removed via wedge excision of the eyelid. Definitive clearance was achieved through Mohs micrographic surgery. The patient received adjuvant postoperative radiotherapy and remains disease-free. This case demonstrates the need to consider sinister pathology in the setting of recurrent periocular lesions...
April 2017: Orbit
https://www.readbyqxmd.com/read/28384651/surgical-treatment-of-subungual-squamous-cell-carcinoma-by-wide-excision-of-the-nail-unit-and-skin-graft-reconstruction-an-evaluation-of-treatment-efficiency-and-outcomes
#8
Solène Topin-Ruiz, Catherine Surinach, Stéphane Dalle, Gérard Duru, Brigitte Balme, Luc Thomas
Importance: The best surgical treatment modalities for subungual squamous cell carcinoma (SUSCC) without bone invasion need to be determined. The limited available data on Mohs micrographic surgery do not demonstrate its use as a standard procedure. A previous study in a limited series of patients has shown that wide surgical excision of the nail unit was associated with a low rate of recurrence. Objectives: To confirm the efficiency of wide surgical excision of the nail unit with full-thickness skin graft reconstruction on a series of patients with SUSCC with an extended follow-up and to evaluate short- and long-term postoperative morbidity and patient satisfaction...
April 5, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28367092/pkd-knockdown-inhibits-pressure-overload-induced-cardiac-hypertrophy-by-promoting-autophagy-via-akt-mtor-pathway
#9
Di Zhao, Wei Wang, Hao Wang, Honghai Peng, Xiangjuan Liu, Weixing Guo, Guohai Su, Zhuo Zhao
Growing evidence shows that protein kinase D (PKD) plays an important role in the development of pressure overload-induced cardiac hypertrophy. However, the mechanisms involved are not clear. This study tested our hypothesis that PKD might mediate cardiac hypertrophy by negatively regulating autophagy using the technique of PKD knockdown by siRNA. Cardiac hypertrophy was induced in 8-week old male C57BL/6 mice by transverse aortic constriction (TAC). TAC mice were then divided into five groups receiving the treatments of vehicle (DMSO), an autophagy inducer rapamycin (1 mg/kg/day, i...
2017: International Journal of Biological Sciences
https://www.readbyqxmd.com/read/28365039/tumor-recurrence-of-keratinocyte-carcinomas-judged-appropriate-for-mohs-micrographic-surgery-using-appropriate-use-criteria
#10
Sarah E Stuart, Patrick Schoen, Chengshi Jin, Rupa Parvataneni, Sarah Arron, Eleni Linos, W John Boscardin, Mary-Margaret Chren
BACKGROUND: The use of Mohs micrographic surgery (MMS) has increased greatly to treat basal cell and cutaneous squamous cell carcinomas (keratinocyte carcinoma [KC]), and consensus-based Appropriate Use Criteria (AUC) were developed to identify tumors for which MMS is appropriate. OBJECTIVE: We sought to compare recurrence rates after different treatments in tumors judged appropriate for MMS. METHODS: We used data from an observational prospective cohort study and retrospectively categorized consecutive tumors as appropriate for MMS according to the AUC...
March 29, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28342837/-malignant-cutaneous-adnexal-neoplasms-of-the-face-and-scalp-diagnostic-and-therapeutic-update
#11
M Romeu, J M Foletti, C Chossegros, J P Dales, P Berbis, B Cribier, L Guyot
INTRODUCTION: Malignant cutaneous adnexal neoplasms are rare and have been characterized only recently. They can occur at any age but preferentially in elderly. There are 3 of them: trichoblastic carcinoma, trichilemmal carcinoma and malignant pilomatricoma. The aim of our study was to make a diagnostic and therapeutic update about these tumors when located at the face or at the scalp. MATERIALS AND METHODS: A bibliographic research was made on PubMed using following keywords: appendage skin carcinoma AND pathology AND/OR therapeutic...
March 22, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28329594/perforating-gout-of-the-ear
#12
Leigh Sutton, Palak Parekh
Gout is the most common cause of inflammatory arthritis in men over 40 [1]. The prevalence of gout in the US is approximately 3.9%. Tophus is a characteristic sign of gout and results when monosodium urate deposits at the joint, skin, or cartilage. Tophi develop in 12-35% of patients who are diagnosed with gout [2]. We report a case of a 70-year-old man who was diagnosed with squamous cell carcinoma of the helix via shave biopsy. During Mohs micrographic surgery, a vigorous foreign-body reaction was noted. Review of the initial biopsy slides identified crystals with pseudoepitheliomatous hyperplasia (PEH) rendering a diagnosis of gout...
October 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28329584/reusing-surgical-instruments-during-mohs-micrographic-surgery-safe-from-infection-but-not-free-from-risk
#13
Tatyana A Petukhova, Thomas H King, Kenny J Omlin, Daniel B Eisen
We report several scenarios of compromise in patient safety owing to the re-use of mis-assigned patient's surgical instruments in Mohs micrographic surgery.We discuss the breaks in universal protocols that others may experience in their practices and describe corrective measures that our institutions employed to avoid such future events.There is a lack of publication in the literature on the topic of mis-assigned instrument use in Mohs surgery. We believe that the  practice of re-using instruments is cost-effective and therefore common...
October 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28329499/mohs-micrographic-surgery-and-secondary-intention-healing-of-a-plantar-melanoma-in-situ
#14
Jason Schoenfeld, Paul Wirth, Thomas Helm
This report details an acral melanoma in-situ on theright plantar foot that was successfully treated withMohs micrographic surgery and secondary intentionwound healing.
February 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28328703/functionality-of-patients-75-years-and-older-undergoing-mohs-micrographic-surgery-a-multicenter-study
#15
Christie G Regula, Murad Alam, Ramona Behshad, Marc Glashofer, C William Hanke, Christopher Harmon, Ryan Johnson, David Kent, Patrick Lee, Naomi Lawrence
BACKGROUND: Mohs surgery is indisputably a highly effective treatment for nonmelanoma skin cancers. In the current health care environment, physicians are challenged to provide high quality, efficacious care in a manner that is mindful of the patient's general health and well-being. We have used a functional assessment to evaluate older patients who present for Mohs surgery. OBJECTIVE: The purpose of this study is to categorize the functional status, using the Karnofsky Performance Status (KPS) Scale, of patients 75 years and older undergoing Mohs surgery of a nonmelanoma skin cancer and to identify distinguishing characteristics of lower functioning patients...
March 21, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28323653/herpes-zoster-at-the-site-of-mohs-micrographic-surgery-in-an-immunocompromised-individual
#16
Renee Domozych, Elizabeth Brezinski Wallace, Victor Allen Neel, Daniela Kroshinsky
No abstract text is available yet for this article.
March 17, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28323651/clinical-features-and-treatment-of-dermatofibrosarcoma-protuberans-affecting-the-vulva-a-literature-review
#17
Austin H Nguyen, Shannon Q Detty, Maria I Gonzaga, Christopher Huerter
BACKGROUND: Dermatofibrosarcoma protuberans (DFSP) is a low-to-intermediate grade cutaneous neoplasm with a low propensity for metastasis and a high rate of local recurrence. It typically presents as a dermal plaque or nodule on the trunk, limbs, or head and neck region. Vulvar DFSP has also been described, although it is less common. OBJECTIVE: To review the available literature and discuss the clinical course of DFSP affecting the vulva. MATERIALS AND METHODS: We reviewed the existing English-language literature on DFSP of the vulva with respect to clinical presentation, diagnosis, treatment, and outcome...
March 17, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28323649/successful-treatment-of-postoperative-pain-after-mohs-micrographic-surgery-with-onabotulinum-toxin-a
#18
Jennifer L DePry, Margaret Mann
No abstract text is available yet for this article.
March 17, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28319637/online-patient-reported-reviews-of-mohs-micrographic-surgery-qualitative-analysis-of-positive-and-negative-experiences
#19
Shuai Xu, Zaza Atanelov, Ashish C Bhatia
Mohs micrographic surgery (MMS) is the gold standard for treating high-risk skin cancers and skin cancers in areas where skin sparing is essential. However, relatively little is known about patient-reported satisfaction with this procedure. In this study, we used qualitative research methods to determine themes of patient-reported satisfaction and dissatisfaction with MMS on one popular online resource (RealSelf). Real-world patient feedback provides an opportunity for physicians to explore the patient mind-set and to target areas of potential improvement in MMS patient satisfaction...
February 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28300924/staged-retroauricular-flap-for-helical-reconstruction-after-mohs-micrographic-surgery
#20
Felipe Bochnia Cerci
Staged retroauricular flap is a great option for full-thickness defects along the helical rim and antihelix. Donor site consists of the posterior ear, postauricular sulcus and mastoid area. The advantages of this flap include hidden donor scar, donor tissue similarity and rich vascularity. We present a case of collision tumor on the left helix treated with Mohs micrographic surgery and the resulting full-thickness defect repaired with a staged retroauricular flap. This flap is an effective technique for full-thickness helical defect repair with relatively little operative morbidity...
September 2016: Anais Brasileiros de Dermatologia
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