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Marta Aguado Lobo, Elena Sierra Gonzalo, José Jiménez-Reyes
Eosinophilic annular erythema (EAE) is an uncommon eosinophilic dermatosis. Clinically it is characterized by recurrent episodes of annular or figurative plaques. The histopathological study shows a perivascular inflammatory infiltrate in the superficial and deep dermis, composed of lymphocytes and eosinophils. It was originally described in children. We report an adult woman who presented with recurrent erythematous annular plaques on the trunk and extremities. A biopsy showed a mainly perivascular lymphocytic infiltrate with numerous eosinophils in the dermis...
October 15, 2017: Dermatology Online Journal
Rosa E Enacán, María E Masnata, Fiorella Belforte, Patricia Papendieck, María C Olcese, Sofía Siffo, Laura Gruñeiro-Papendieck, Héctor Targovnik, Carina M Rivolta, Ana E Chiesa
Congenital hypothyroidism affects 1:2000-3000 newborns detected by neonatal screening programs. Dual oxidases, DUOX1 and 2, generate hydrogen peroxide needed for the thyroid hormone synthesis. Hipotiroidismo congénito transitorio por defectos bialélicos del gen DUOX2. Dos casos clínicos Transient congenital hypothyroidism due to biallelic defects of DUOX2 gene. Two clinical cases Mutations in the DUOX2 gene have been described in transient and permanent congenital hypothyroidism. Two brothers with congenital hypothyroidism detected by neonatal screening with eutopic gland and elevated thyroglobulin are described...
June 1, 2017: Archivos Argentinos de Pediatría
A De Quintana Sancho, X Piris-García, J N Valle-García, M Hierro-Cámara
Frontal fibrosing alopecia (FFA) is a scarring alopecia whose incidence is increasing significantly in our country. It is characterized by loss of frontotemporal hairline that mostly affects postmenopausal women, with a negative impact on quality of life. It is associated with early menopause in 14% of cases and hypothyroidism in 15%. With regard to treatment, 5α-reductase inhibitors are the drugs that have shown improvement of the disease in a larger number of cases. We report a new case of FFA in a woman of 77 years successfully treated with finasteride at doses of 2...
December 30, 2016: Anales del Sistema Sanitario de Navarra
Ana Isabel Mariscal Hidalgo, José E Lozano Alonso, Tomás Vega Alonso
OBJECTIVE: To describe the distribution of thyroid-stimulating hormone (TSH) values and to estimate the prevalence of subclinical hypothyroidism in the adult population of Castile and León (Spain). METHOD: An observational study was conducted in an opportunistic sample of 45 primary care centers in Castile and León. TSH was determined in people aged ≥35 years that attended a primary care physician and had a blood test for any reason. Confirmatory analysis included free thyroxine and anti-thyroid peroxidase antibody determination...
March 2015: Gaceta Sanitaria
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