Luigi Di Biase, Jorge Romero, David Briceno, Dhanunjaya Lakkireddy, Chintan Trivedi, Prasant Mohanty, Sanghamitra Mohanty, Rodney Horton, Patrick Hranitzky, G Joseph Gallinghouse, Isabella Alviz, Mohit Turagam, Rakesh Gopinathannair, Domenico Giovanni Della Rocca, Salwa Beheiry, John David Burkhardt, Juan Viles-Gonzales, Andrea Natale
BACKGROUND: Direct oral anticoagulants (DOACs) are contraindicated in patients with atrial fibrillation (AF) and mechanical cardiac valves. However, safety and efficacy are controversial in patients with biological cardiac valves. OBJECTIVE: We report the safety and feasibility of periprocedural and long-term treatment with DOACs in patients with biological valves undergoing ablation for AF. METHODS: A total of 127 patients with AF and biological cardiac valve undergoing CA on uninterrupted DOAC were matched by gender and age with 127 patients with AF and biological cardiac valves undergoing CA on uninterrupted warfarin...
September 2021: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing