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https://www.readbyqxmd.com/read/28101236/identification-of-proteins-associated-with-pediatric-bilateral-wilms-tumor
#1
Zechen Yan, Qingjun Meng, Jinjian Yang, Junjie Zhang, Wei Zhao, Fei Guo, Dongjian Song, Yuxiao Zhan, Dandan Fan, Ruiyi Zhou, Shuqiang Zuo, Zehua Wang, Jiekai Yu, Shu Zheng, Jiaxiang Wang
Wilms tumor (WT) is the most common cancer that primarily develops in abdominal solid organ of children. It has no incipient symptom, and the most frequent symptoms are a painless, palpable abdominal mass. Proteomics technology was used to select the differentially expressed proteins of bilateral Wilms tumor (BWT). Ten serum samples of children with BWT were chosen, 20 serum samples of children with unilateral WT (UWT) and 20 serum samples of healthy children were selected, and proteomics technology was used to detect and collect data...
December 2016: Oncology Letters
https://www.readbyqxmd.com/read/28100318/-clinical-characteristics-of-clonal-evolution-after-immunosuppressive-therapy-in-children-with-severe-very-severe-aplastic-anemia
#2
Jing-Liao Zhang, Tian-Feng Liu, Li-Xian Chang, Xia Chen, Yuan-Yuan Ren, Cong-Cong Sun, Chao Liu, Wen-Bin An, Yang Wan, Xiao-Juan Chen, Wen-Yu Yang, Shu-Chun Wang, Ye Guo, Yao Zou, Yu-Mei Chen, Xiao-Fan Zhu
OBJECTIVE: To evaluate the clinical characteristics and risk factors of clonal evolution after immunosuppressive therapy (IST) in children with severe/very severe aplastic anemia (SAA/VSAA). METHODS: The clinical data of 231 children with newly-diagnosed SAA/VSAA who received IST were retrospectively studied. The incidence and risk factors of clonal evolution after IST were analyzed. RESULTS: The 5-year overall survival rate of the 231 patients was 82...
January 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/28099871/fluoride-and-arsenic-exposure-affects-spatial-memory-and-activates-the-erk-creb-signaling-pathway-in-offspring-rats
#3
Yu-Peng Zhu, Shu-Hua Xi, Ming-Yan Li, Ting-Ting Ding, Nan Liu, Fu-Yuan Cao, Yang Zeng, Xiao-Jing Liu, Jun-Wang Tong, Shou-Fang Jiang
Fluoride and arsenic are inorganic contaminants that occur in the natural environment. Chronic fluoride and/or arsenic exposure can induce developmental neurotoxicity and negatively influence intelligence in children, although the underlying molecular mechanisms are poorly understood. This study explored the effects of fluoride and arsenic exposure in drinking water on spatial learning, memory and key protein expression in the ERK/CREB signaling pathway in hippocampal and cerebral cortex tissue in rat offspring...
January 15, 2017: Neurotoxicology
https://www.readbyqxmd.com/read/28092910/effects-of-in-utero-and-postnatal-exposure-to-secondhand-smoke-on-lung-function-by-gender-and-asthma-status-the-seven-northeastern-cities-snec-study
#4
Li-Wen Hu, Mo Yang, Shu Chen, Kuntal Shah, Yismaw Hailegiorgis, Richai Burgens, Michael Vaughn, Jin Huang, Pamela Xaverius, Gunther Paul, Lidia Morawska, Tao Lu, Shao Lin, Shou-Qiang Zhong, Min-Li Kong, Yan-Qi Xie, Yuan-Tao Hao, Xiao-Wen Zeng, Zhengmin Qian, Guang-Hui Dong
BACKGROUND: Little information exists on whether gender or asthma status modifies the effects of secondhand smoke (SHS) exposure on lung function. OBJECTIVE: To evaluate whether gender or asthma status modifies the association of SHS exposure with lung function. METHODS: A total of 6,740 children (average 11.6 years) were recruited from 24 districts of 7 cities in northeast China in 2012. SHS exposure included exposure to environmental and maternal smoking both in utero and during early childhood (postnatal)...
January 17, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28079808/diagnosis-and-treatment-of-pediatric-benign-pneumoperitoneum-a-case-report-series-of-9-patients
#5
Shou-Xing Duan, Zong-Bo Sun, Guang-Huan Wang, Jun Zhong, Wen-Hui Ou, Ma-Xian Fu, Fu-Sheng Wang, Shu-Hua Ma, Jian-Hong Li
INTRODUCTION: Benign pneumoperitoneum (BPPT) is defined as asymptomatic free intraabdominal air or as pneumoperitoneum without peritonitis. Symptomatic free air requires surgical anagement, but management of asymptomatic pneumoperitoneum is controversial. In this study, we investigate the diagnosis and treatment of BPPT in children. CLINICAL FINDINGS: The clinical data of 9 pediatric patients with BPPT who were admitted to our hospital from January 2000 to January 2015 were retrospectively analyzed to summarize the diagnosis and treatment...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28072743/bilateral-anterior-capsulotomy-and-amygdalotomy-for-mental-retardation-with-psychiatric-symptoms-and-aggression-a-case-report
#6
Shizhen Zhang, Peizhi Zhou, Shu Jiang, Peng Li, Wei Wang
RATIONALE: Mental retardation (MR) is a chronic condition that often has no readily identifiable cause or treatment. Aggression and psychiatric symptoms are prevalent in children with MR. Surgical treatment of aggression and psychiatric symptoms of MR is seldom investigated and studies are limited. PATIENT CONCERNS: We encountered a 19-year-old female who had MR with aggression and psychiatric symptoms. DIAGNOSES: She was diagnosed with mild MR with aggressiveness and psychiatric symptoms...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28062882/anaphylaxis-in-children-experience-of-485-episodes-in-1-272-482-patient-attendances-at-a-tertiary-paediatric-emergency-department-from-2007-to-2014
#7
Sashikumar Ganapathy, Zaw Lwin, Daniel Ha Ting, Lynette Sh Goh, Shu Ling Chong
Introduction: Anaphylaxis is a predominantly childhood disease. Most of the literature on anaphylaxis has emerged from Western countries. This study aimed to describe the incidence, triggers and clinical presentation of anaphylaxis among children in Singapore, look for predictors for anaphylaxis with severe outcomes, and study the incidence of biphasic reactions. Materials and Methods: We retrospectively reviewed records of children presenting with anaphylaxis to our paediatric emergency department from 1 January 2007 to 31 December 2014...
December 2016: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/28060046/serious-adverse-reactions-from-anti-tuberculosis-drugs-among-599-children-hospitalized-for-tuberculosis
#8
Yiyuan Li, Yu Zhu, Qin Zhong, Xiaojun Zhang, Min Shu, Chaomin Wan
BACKGROUNDS: The purpose of the study was to summarize the clinical characteristics of serious adverse reactions (ARs) related to anti-tuberculosis (TB) drugs in children hospitalized for TB. A comprehensive understanding of these drug-related ARs may serve to improve patient prognosis. METHOD: Inpatients diagnosed with TB from 2008 to 2013 were enrolled retrospectively. The patients' demographics, diagnosis and ARs were recorded and analyzed for comprehensive evaluation...
January 3, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28040525/factors-associated-with-surgical-outcomes-in-congenital-ptosis-a-10-year-study-of-319-cases
#9
Yeen-Fey Ho, Shu-Ya Wu, Yueh-Ju Tsai
PURPOSE: To evaluate the 10-year results of surgery for congenital ptosis and identify factors associated with excellent outcomes and recurrence.
 DESIGN: Retrospective, interventional case series.
 METHODS: A retrospective analysis was conducted of 319 patients who underwent surgical correction at a tertiary medical center for congenital ptosis. The main outcome measures were postoperative surgical outcomes and recurrence rates. Excellent lid height was assessed as a marginal reflex distance (MRD) greater than 3 mm...
December 28, 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28005698/prenatal-and-postnatal-exposure-to-pet-ownership-blood-pressure-and-hypertension-in-children-the-seven-northeastern-cities-study
#10
Shu-Li Xu, Edwin Trevathan, Zhengmin Qian, Elaina Vivian, Bo-Yi Yang, Li-Wen Hu, Xiao-Wen Zeng, Meng Li, Yang Zhou, Xiao-Di Qin, Wen-Wen Bao, Ping Yuan, Ya-Zhi Zhang, Jia Wang, Chuan Zhang, Yan-Peng Tian, Min Nian, Xiang Xiao, Guang-Hui Dong
OBJECTIVE: There is little information about how exposure to pets impacts blood pressure (BP) in children. The objective of the present study was to investigate the association between pet exposure and BP in children. METHODS: A total of 9354 children, aged 5-17 years, from 24 elementary schools and 24 middle schools in the Seven Northeastern Cities were evaluated during 2012-2013. BP measurements were taken using a mercury sphygmomanometer. Hypertension in children was defined as having an average DBP or SBP in the 95th percentile or higher for the child's sex, age, and height...
February 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28002138/the-effectiveness-of-health-education-on-maternal-anxiety-circumcision-knowledge-and-nursing-hours-a-quasi-experimental-study
#11
Shu-Fang Chang, Chich-Hsiu Hung, Yu-Yun Hsu, Yi Liu, Tsu-Nai Wang
BACKGROUND: Many studies have shown that providing health education before surgery may significantly increase health knowledge and decrease anxiety in both patients and their family members. However, few studies have compared the effects on pediatric outpatient surgery outcomes of different health education instruction modes. PURPOSE: This study compares the effects of two health education delivery modes on maternal knowledge and anxiety, the number of unexpected early hospital follow-up visits, and the time spent by nurses on health education...
December 19, 2016: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/27998861/-risk-factors-for-acute-respiratory-distress-syndrome-following-surgeries-for-pediatric-critical-and-complex-congenital-heart-disease
#12
Shu-Rong Gong, Ying-Rui Zhang, Rong-Guo Yu
OBJECTIVE: To explore the risk factors for acute respiratory distress syndrome (ARDS) in children receiving surgeries for critical and complex congenital heart disease (CCHD). METHODS: According to the 2011's Berlin definition of ARDS, the clinical data were collected from 75 children without ARDS (group I) and 80 children with ARDS (group II) following surgeries for CCHD performed in the Department of Cardiac Surgery of our hospital from January, 2009 to May, 2014...
December 20, 2016: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/27995225/oral-health-status-and-oral-health-care-model-in-china
#13
Jian Liu, Shan Shan Zhang, Shu Guo Zheng, Tao Xu, Yan Si
OBJECTIVE: To review the current oral health status and oral health care models in China in an effort to provide recommendations for the future implementation of these models. METHODS: A systematic literature review was conducted. The Medline, EMBASE, CNKI and Wanfang databases were searched for English and Chinese articles reporting relevant data from 1949 to the present. Data from three national oral health epidemiology surveys, Chinese government reports and national statistics yearbooks from 2011 to 2015 were also included...
2016: Chinese Journal of Dental Research
https://www.readbyqxmd.com/read/27974125/-clinical-features-of-mild-encephalitis-encephalopathy-with-a-reversible-splenial-lesion-in-children
#14
Yin Liu, Guang-Min Li, Shu-Hua Li, Xiao-Qing Wang, Su-Rong Li, Jing Zhang, Hong-Fang Wang, Bao-Dong Pang, Jia-Hua Wu
OBJECTIVE: To investigate the clinical features of mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) in children. METHODS: The clinical data of 8 children with MERS were retrospectively analyzed. RESULTS: The mean age of onset was 5 years and 2 months (range 10 months to 12 years). The major clinical features included a history of prodromal infection, and among these children, 5 had pyrexia and 4 had vomiting. Of all the children, 6 were manifested as convulsion and 3 each were manifested as disturbance of consciousness and paroxysmal paropsia...
December 2016: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/27957762/serum-tnf-%C3%AE-levels-in-children-with-congenital-heart-disease-undergoing-cardiopulmonary-bypass-a-cohort-study-in-china-and-a-meta-analysis-of-the-published-literature
#15
Shu-Tian Song, Chuan-Ming Bai, Ji-Wu Zhou
OBJECTIVE: To investigate the changes in tumor necrosis factor alpha (TNF-α) serum levels after cardiopulmonary bypass (CPB) in children with congenital heart disease (CHD), followed by a meta-analysis to analyze the clinical value of TNF-α in CPB. METHODS: Our cohort study enrolled 67 CHD children, assigned into off-pump group (n=32) and CPB group (n=35). The TNF-α serum levels in two groups were detected by ELISA before the operation (T1), at the end of the operation (0 hour, T2), and after 24 hours of the operation (T3)...
December 13, 2016: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/27928698/urban-and-education-disparity-for-autism-spectrum-disorders-in-taiwan-birth-cohort-study
#16
For-Wey Lung, Tung-Liang Chiang, Shio-Jean Lin, Bih-Ching Shu
This study aimed to determine the optimal cut-off for autism spectrum disorder (ASD) screening in 66-month-old children, and to explore the distribution of ASD screening and diagnosis in Taiwan. The Taiwan Birth Cohort Study dataset was used (N = 20,095). The Modified Checklist for Autism in Toddlers (M-CHAT) cut-off point of 13/14 was considered optimal for screening of children at 66 months. More children were diagnosed with ASD in urban areas. Parents of children diagnosed with ASD had a higher level of education, but parents of children with a lower level of education were screened as being at higher risk of ASD...
December 7, 2016: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/27893696/molecular-epidemiological-study-of-enteroviruses-associated-with-encephalitis-in-children-from-hangzhou-china
#17
Wei Li, Zhang Qiong, Shen Xiao-Ting, Liu Yu-Jie, Mao Jian-Hua, Shu Qiang, Shang Shi-Qiang
Enterovirus (EV) has over 100 serotypes of species A-D, which can cause various symptoms in infants. Enterovirus encephalitis (EVE) is serve disease with high morbidity and mortality in children. To well define the epidemiology of EVE, we wanted to know more about EV and EV molecular typing by conducting this study in Hangzhou.Cerebrospinal fluid samples were collected from children with diagnosis of encephalitis. Meanwhile, one-step real-time RT-PCR was used for the detection of EV, and we also identified the serotypes of EV by using gene sequencing of VP1 or 5'UTR region...
October 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27889737/immune-thrombocytopenic-purpura-in-children-of-eastern-henan-province-china
#18
Qiu-Xia Fan, Chun-Mei Wang, Shu-Xia Chen, Xin-Guang Liu, Bo Han
In this retrospective cohort study conducted in 63 children with idiopathic thrombocytopenic purpura (ITP) in China; petechiae, bruises and bleeding were the major presentations. Most cases required therapy with one/more treatment options.
November 15, 2016: Indian Pediatrics
https://www.readbyqxmd.com/read/27887573/in-vitro-function-of-upstream-visfatin-polymorphisms-that-are-associated-with-adverse-cardiometabolic-parameters-in-obese-children
#19
Delicia Shu Qin Ooi, Siong Gim Ong, Chew Kiat Heng, Kah Yin Loke, Yung Seng Lee
BACKGROUND: Visfatin is an adipokine associated with glucose and lipid metabolism. We previously reported two visfatin upstream single nucleotide polymorphisms (SNPs), c.-3187G > A (rs11977021) and c.-1537C > T (rs61330082), which were in perfect linkage disequilibrium, in a Singaporean cohort of severely obese children and are associated with visfatin level and adverse cardiometabolic parameters. We aim to functionally characterize the effect of c.-3187G > A and c...
November 25, 2016: BMC Genomics
https://www.readbyqxmd.com/read/27883911/examining-the-relationship-between-rapid-automatized-naming-and-arithmetic-fluency-in-chinese-kindergarten-children
#20
Jiaxin Cui, George K Georgiou, Yiyun Zhang, Yixun Li, Hua Shu, Xinlin Zhou
Rapid automatized naming (RAN) has been found to predict mathematics. However, the nature of their relationship remains unclear. Thus, the purpose of this study was twofold: (a) to examine how RAN (numeric and non-numeric) predicts a subdomain of mathematics (arithmetic fluency) and (b) to examine what processing skills may account for the RAN-arithmetic fluency relationship. A total of 160 third-year kindergarten Chinese children (83 boys and 77 girls, mean age=5.11years) were assessed on RAN (colors, objects, digits, and dice), nonverbal IQ, visual-verbal paired associate learning, phonological awareness, short-term memory, speed of processing, approximate number system acuity, and arithmetic fluency (addition and subtraction)...
February 2017: Journal of Experimental Child Psychology
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