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https://www.readbyqxmd.com/read/28342962/intellectual-evaluation-of-children-exposed-to-phthalate-tainted-products-after-the-2011-taiwan-phthalate-episode
#1
Po-Chin Huang, Chih-Hsin Tsai, Chu-Chih Chen, Ming-Tsang Wu, Mei-Lien Chen, Shu-Li Wang, Bai-Hsiun Chen, Ching-Chang Lee, Jouni J K Jaakkola, Wen-Chiu Wu, Min-Kung Chen, Chao A Hsiung, Rapit Group
INTRODUCTION: Phthalate exposure may reduce intellectual development in young children. In 2011, numerous Taiwanese children had been reported to have consumed phthalate-tainted products. We investigated the effects of phthalate exposure on the intellectual development of these children after the 2011 Taiwan di-2-ethylhexyl phthalate (DEHP) episode. METHODS: We recruited 204 children, aged 3-12 y, from 3 hospitals in Taiwan between 2012 and 2013. First-morning urine samples were collected for analyzing 5 phthalate metabolites...
March 23, 2017: Environmental Research
https://www.readbyqxmd.com/read/28336364/mechanisms-and-roles-by-which-irf-3-mediates-the-regulation-of-ormdl3-transcription-in-respiratory-syncytial-virus-infection
#2
Xiao-Hua Wang, Jin Shu, Chun-Ming Jiang, Li-Li Zhuang, Wei-Xia Yang, Hui-Weng Zhang, Lu-Lu Wang, Lin Li, Xiao-Qing Chen, Rui Jin, Guo-Ping Zhou
Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis in infancy, which is a major risk factor for recurrent wheezing and asthma. Orosomucoid 1-Like Protein 3 (ORMDL3) has been reported to associate with virus-triggered recurrent wheezing and asthma in children. However, little is known about how ORMDL3 is involved into RSV infection. In this study, we showed that the mRNA expression of ORMDL3 is significantly increased in the peripheral blood lymphocytes of infants with RSV-induced bronchiolitis compared with uninfected controls, also increased in bronchial epithelial cells and lung fibroblasts following RSV infection in vitro...
March 20, 2017: International Journal of Biochemistry & Cell Biology
https://www.readbyqxmd.com/read/28334944/recent-trends-in-body-mass-index-and-waist-circumference-among-children-and-adolescents-in-shandong-china
#3
Ying-Xiu Zhang, Shu-Rong Wang, Min Chen, Yan Cheng
Background: The present study examined the recent trends in body mass index (BMI) and waist circumference (WC), and the prevalence of general and abdominal obesity among children and adolescents in Shandong, China. Methods: Data for this study were obtained from two cross-sectional surveys of schoolchildren carried out in 2010 and 2014 in Shandong Province, China. A total of 72 755 students aged 7-18 years were included in this study. The BMI cutoff points recommended by the International Obesity Task Force were used to define overweight and general obesity...
March 8, 2017: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/28334670/spatial-distribution-emission-source-and-health-risk-of-parent-pahs-and-derivatives-in-surface-soils-from-the-yangtze-river-delta-eastern-china
#4
ChuanYang Cai, JingYa Li, Di Wu, XiLong Wang, Daniel C W Tsang, XiangDong Li, JianTeng Sun, LiZhong Zhu, HuiZhong Shen, Shu Tao, WenXin Liu
243 surface soil samples were collected from the Yangtze River Delta (YRD) region, and the concentration distributions and compositional profiles of 27 parent PAHs (PPAHs), nitro- and oxy-derivatives (NPAHs and OPAHs), respectively, and health risk of 16 PPAHs were determined. Atmospheric samples were collected at two sites with high topsoil concentrations of PAHs to assist in identifying the emission sources of PPAHs. The total concentrations of PPAHs, NPAHs and OPAHs fell in the ranges of 21.0-3563.2 ng/g, 0...
March 16, 2017: Chemosphere
https://www.readbyqxmd.com/read/28334252/individualized-prediction-of-reading-comprehension-ability-using-gray-matter-volume
#5
Zaixu Cui, Mengmeng Su, Liangjie Li, Hua Shu, Gaolang Gong
Reading comprehension is a crucial reading skill for learning and putatively contains 2 key components: reading decoding and linguistic comprehension. Current understanding of the neural mechanism underlying these reading comprehension components is lacking, and whether and how neuroanatomical features can be used to predict these 2 skills remain largely unexplored. In the present study, we analyzed a large sample from the Human Connectome Project (HCP) dataset and successfully built multivariate predictive models for these 2 skills using whole-brain gray matter volume features...
March 10, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28328807/associations-of-il-4-il-6-and-il-12-levels-in-peripheral-blood-with-lung-function-cellular-immune-function-and-quality-of-life-in-children-with-moderate-to-severe-asthma
#6
Ai-Hua Cui, Jing Zhao, Shu-Xiang Liu, Ying-Shuang Hao
BACKGROUND: Pediatric asthma has gained increasing concerns with poorly understood pathogenesis. The purpose of this study was to explore the associations of interleukin-4 (IL-4), IL-6, and IL-12 levels in peripheral blood (PB) with lung function, cellular immune function, and children's quality of life (QOL) with moderate-to-severe asthma. METHODS: A total of 1158 children with moderate-to-severe asthma (the experimental group) and 1075 healthy children (the control group) were recruited for our study...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28321694/the-born-in-guangzhou-cohort-study-bigcs
#7
Xiu Qiu, Jin-Hua Lu, Jian-Rong He, Kin-Bong Hubert Lam, Song-Ying Shen, Yong Guo, Ya-Shu Kuang, Ming-Yang Yuan, Lan Qiu, Nian-Nian Chen, Min-Shan Lu, Wei-Dong Li, Yan-Fei Xing, Feng-Juan Zhou, Suzanne Bartington, Kar Keung Cheng, Hui-Min Xia
The Born in Guangzhou Cohort Study (BIGCS) is a large-scale prospective observational study investigating the role of social, biological and environmental influences on pregnancy and child health and development in an urban setting in southern China. Pregnant women who reside in Guangzhou and who attend Guangzhou Women and Children's Medical Center (GWCMC) for antenatal care in early pregnancy (<20 weeks' gestation) are eligible for inclusion. Study recruitment commenced in February 2012, with an overall participation rate of 76...
March 20, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28303423/theory-of-mind-predominantly-associated-with-the-quality-not-quantity-of-pretend-play-in-children-with-autism-spectrum-disorder
#8
Shu-Kai Lin, Ching-Hong Tsai, Hsing-Jung Li, Chien-Yu Huang, Kuan-Lin Chen
This study aimed to clarify the relationships between theory of mind and pretend play in children with autism spectrum disorder, using refined assessments of theory of mind and pretend play while controlling for autistic behaviors and verbal comprehension. A total of 92 children with autism spectrum disorder aged 4-10 years were enrolled. In two visits, the children were assessed with the Theory of Mind Task Battery, the Child-Initiated Pretend Play Assessment, the Childhood Autism Rating Scale, and the Verbal Comprehension Index of the Wechsler Intelligence Scales, respectively, for their theory of mind, pretend play performance, autistic behaviors, and verbal comprehension...
March 16, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28302205/-value-of-nutritional-risk-screening-in-evaluating-adverse-clinical-outcomes-in-children-with-severe-pneumonia
#9
Xiao-Hui Guo, Yan-Feng Sun, Jiang-Bo Wang, Shu-Zhen Han, Jing Miao, Min Cui
OBJECTIVE: To investigate the nutritional risk in children with severe pneumonia using the Screening Tool for the Assessment of Malnutrition in Paediatrics (STAMP) and the association between nutritional risk and adverse clinical outcomes. METHODS: According to the STAMP score, 216 children with severe pneumonia were classified into high nutritional risk group (HR group; n=98), moderate nutritional risk group (MR group; n=65), and low nutritional risk group (LR group; n=53)...
March 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/28296528/the-impact-of-early-hyperglycaemia-on-children-with-traumatic-brain-injury
#10
Yue-Qiang Fu, Shu-Ling Chong, Jan Hau Lee, Cheng-Jun Liu, Sheng Fu, Tsee Foong Loh, Kee Chong Ng, Feng Xu
OBJECTIVE: Hyperglycaemia is common amongst children with traumatic brain injury (TBI). We aim to investigate the association between early hyperglycaemia and poor clinical outcomes in children with moderate to severe TBI. METHODS: We performed a retrospective study in a tertiary paediatric hospital between May 2012 and October 2014 of all patients with TBI who were aged <16 years with a Glasgow Coma Scale (GCS) of ≤13. The primary outcome was death. Secondary outcomes were 14 ventilation-free, 14 paediatric intensive care unit (PICU)-free and 28 hospital-free days...
2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28279395/resilience-model-for-parents-of-children-with-cancer-in-mainland-china-an-exploratory-study
#11
Zeng Jie Ye, Hong Zhong Qiu, Peng Fei Li, Mu Zi Liang, Shu Ni Wang, Xiao Ming Quan
PURPOSE: Parents have psychosocial functions that are critical for the entire family. Therefore, when their child is diagnosed with cancer, it is important that they exhibit resilience, which is the ability to preserve their emotional and physical well-being in the face of stress. The Resilience Model for Parents of Children with Cancer (RMP-CC) was developed to increase our understanding of how resilience is positively and negatively affected by protective and risk factors, respectively, in Chinese parents with children diagnosed with cancer...
April 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/28279394/validation-and-application-of-the-chinese-version-of-the-10-item-connor-davidson-resilience-scale-cd-risc-10-among-parents-of-children-with-cancer-diagnosis
#12
Zeng Jie Ye, Hong Zhong Qiu, Peng Fei Li, Peng Chen, Mu Zi Liang, Mei Ling Liu, Yuan Liang Yu, Shu Ni Wang, Xiao Ming Quan
PURPOSE: Parents of children diagnosed with cancer often experience considerable emotional distress for their children with negative emotions, such as disbelief, depression, anxiety, hope and shock. Resilience is defined as the psychological characteristics that promote positive adaptation in the face of stress and adversity, which has been demonstrated to relate to positive coping and less psychological distress. Thus, a quick screening tool to evaluate the levels of resilience of parents with cancer-diagnosed children is urgently required...
April 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/28259583/positive-association-between-short-term-ambient-air-pollution-exposure-and-children-blood-pressure-in-china-result-from-the-seven-northeast-cities-snec-study
#13
Xiao-Wen Zeng, Zhengmin Min Qian, Michael G Vaughn, Erik J Nelson, Shyamali C Dharmage, Gayan Bowatte, Jennifer Perret, Duo-Hong Chen, Huimin Ma, Shao Lin, Benjamin de Foy, Li-Wen Hu, Bo-Yi Yang, Shu-Li Xu, Chuan Zhang, Yan-Peng Tian, Min Nian, Jia Wang, Xiang Xiao, Wen-Wen Bao, Ya-Zhi Zhang, Guang-Hui Dong
The impact of ambient air pollution on health causes concerns in China. However, little is known about the association of short-term air pollution exposure with blood pressure (BP) in children. The goal of present study was to assess the association between short-term air pollution and BP in children from a highly polluted area in China. This study enrolled 9354 children in 24 elementary and middle schools (aged 5-17 years) from the Seven Northeast Cities (SNEC) study, respectively, during the period of 2012-2013...
March 2, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28258508/a-volumetric-and-functional-connectivity-mri-study-of-brain-arginine-vasopressin-pathways-in-autistic-children
#14
Xiao-Jing Shou, Xin-Jie Xu, Xiang-Zhu Zeng, Ying Liu, Hui-Shu Yuan, Yan Xing, Mei-Xiang Jia, Qing-Yun Wei, Song-Ping Han, Rong Zhang, Ji-Sheng Han
Dysfunction of brain-derived arginine-vasopressin (AVP) systems may be involved in the etiology of autism spectrum disorder (ASD). Certain regions such as the hypothalamus, amygdala, and hippocampus are known to contain either AVP neurons or terminals and may play an important role in regulating complex social behaviors. The present study was designed to investigate the concomitant changes in autistic behaviors, circulating AVP levels, and the structure and functional connectivity (FC) of specific brain regions in autistic children compared with typically developing children (TDC) aged from 3 to 5 years...
April 2017: Neuroscience Bulletin
https://www.readbyqxmd.com/read/28254080/reliability-and-validity-of-ds-adhd-a-decision-support-system-on-attention-deficit-hyperactivity-disorders
#15
Kuo-Chung Chu, Yu-Shu Huang, Chien-Fu Tseng, Hsin-Jou Huang, Chih-Huan Wang, Hsin-Yi Tai
BACKGROUND AND OBJECTIVES: The purpose of this study is to examine the reliability of the clinical use of the self-built decision support system, diagnosis-supported attention deficit hyperactivity disorder (DS-ADHD), in an effort to develop the DS-ADHD system, by probing into the development of indicating patterns of past screening support systems for ADHD. METHODS: The study collected data based on 107 subjects, who were divided into two groups, non-ADHD and ADHD, based on the doctor's determination, using the DSM-IV diagnostic standards...
March 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28252669/association-of-blood-heavy-metals-with-developmental-delays-and-health-status-in-children
#16
Yu-Mei Hsueh, Chih-Ying Lee, Ssu-Ning Chien, Wei-Jen Chen, Horng-Sheng Shiue, Shiau-Rung Huang, Ming-I Lin, Shu-Chi Mu, Ru-Lan Hsieh
The aim of this study was to evaluate the association of blood lead, mercury, and cadmium concentrations with developmental delays and to explore the association of these concentrations with the health status of children. This study recruited 89 children with developmental delays and 89 age- and sex-matched children with typical development. Their health status was evaluated using the Pediatric Quality of Life (PedsQL) Inventory for health-related quality of life (HRQOL) and the Pediatric Outcomes Data Collection Instrument for function...
March 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28240421/robo1-polymorphisms-callosal-connectivity-and-reading-skills
#17
Xiaochen Sun, Shuang Song, Xinyu Liang, Yachao Xie, Chenxi Zhao, Yuping Zhang, Hua Shu, Gaolang Gong
The genetic effects on specific behavioral phenotypes are putatively mediated by specific neural functions. It remains unexplored how the axon-guidance-receptor gene ROBO1 influences reading performance through the neural system despite the identification of ROBO1 as a susceptibility gene for dyslexia. To address this issue, the present study recruited a group of children with a wide range of reading abilities. Two previously identified reading-related ROBO1 polymorphisms were genotyped, and diffusion and structural MRI were acquired to measure the fiber microstructure of the corpus callosum (CC), the major white-matter tract that connects inter-hemispheric cortical regions...
February 27, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28239958/differential-sex-effects-of-systolic-blood-pressure-and-ldl-c-on-type-2-diabetes-life-course-data-from-the-bogalusa-heart-study
#18
Benjamin D Pollock, Wei Chen, Emily W Harville, Tian Shu, Vivian Fonseca, Franck Mauvais-Jarvis, Tanika N Kelly, Lydia A Bazzano
BACKGROUND: There may be sex-specific cardiometabolic mechanisms early in life that affect the development of type 2 diabetes (T2DM) through mid-adulthood. Yet, there have been few studies examining whether early life-course interactions between cardiometabolic risk factors and sex are associated with incident T2DM. METHODS: We followed n = 7,725 children from the Bogalusa Heart Study through mid-adulthood to examine whether low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein-cholesterol (HDL-C), body mass index (BMI), or systolic blood pressure (SBP) differentially impact the risk of T2DM for females versus males...
February 27, 2017: Journal of Diabetes
https://www.readbyqxmd.com/read/28237296/frontal-subcortical-circuitry-in-social-attachment-and-relationships-a-cross-sectional-fmri-ale-meta-analysis
#19
Shu-Hui Lee, Zachary M Walker, James B Hale, S H Annabel Chen
Researchers have explored the concept of attachment in multiple ways, from animal studies examining imprinting to abnormal attachment in psychopathology. However, until recently, few have considered how neural circuitry develops the effective social bonds that are subsequently replicated in relationships across the lifespan. This current cross-sectional study undertook a fMRI Activation Likelihood Estimation (ALE) meta-analyses to examine the neurocircuitry that governs emotional and behavioural functions critical for building effective social relationships in children and adults...
February 22, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28236860/effect-of-equipotent-doses-of-bupivacaine-and-ropivacaine-in-high-fat-diet-fed-neonatal-rodent-model
#20
Ying-Dong Lian, Zong-Xiang Chen, Kang-Ru Zhu, Shu-Yin Sun, Li-Ping Zhu
OBJECTIVES: The increase in the prevalence of obesity presents a significant health and economic problem. Obesity has been reported to be a major contributor to variety of chronic diseases. Childhood obesity has been rising over the past decades leading to various complications in health. Millions of infants and children undergo surgery every year on various health grounds. The present investigation was undertaken to evaluate the effect of spinal anesthesia of equipotent doses of ropivacaine and bupivacaine on over-weight neonatal rats...
March 2017: Brazilian Journal of Anesthesiology
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