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https://www.readbyqxmd.com/read/29675741/collision-cross-sections-and-ion-mobility-separation-of-fragment-ions-from-complex-n-glycans
#1
David J Harvey, Yasunori Watanabe, Joel D Allen, Pauline Rudd, Kevin Pagel, Max Crispin, Weston B Struwe
Ion mobility mass spectrometry (IM-MS) holds great potential for structural glycobiology, in particular in its ability to resolve glycan isomers. Generally, IM-MS has largely been applied to intact glycoconjugate ions with reports focusing on the separation of different adduct types. Here, we explore IM separation and report the collision cross section (CCS) of complex type N-glycans and their fragments in negative ion mode following collision-induced dissociation (CID). CCSs of isomeric fragment ions were found, in some cases, to reveal structural details that were not present in CID spectra themselves...
April 19, 2018: Journal of the American Society for Mass Spectrometry
https://www.readbyqxmd.com/read/29675032/fspp-a-tool-for-genome-wide-prediction-of-smorf-encoded-peptides-and-their-functions
#2
Hui Li, Li Xiao, Lili Zhang, Jiarui Wu, Bin Wei, Ninghui Sun, Yi Zhao
smORFs are small open reading frames of less than 100 codons. Recent low throughput experiments showed a lot of smORF-encoded peptides (SEPs) played crucial rule in processes such as regulation of transcription or translation, transportation through membranes and the antimicrobial activity. In order to gather more functional SEPs, it is necessary to have access to genome-wide prediction tools to give profound directions for low throughput experiments. In this study, we put forward a functional smORF-encoded peptides predictor (FSPP) which tended to predict authentic SEPs and their functions in a high throughput method...
2018: Frontiers in Genetics
https://www.readbyqxmd.com/read/29673810/a-systematic-review-of-emerging-respiratory-viruses-at-the-hajj-and-possible-coinfection-with-streptococcus-pneumoniae
#3
REVIEW
Jaffar A Al-Tawfiq, Samir Benkouiten, Ziad A Memish
BACKGROUND: The annual Hajj to the Kingdom of Saudi Arabia attracts millions of pilgrims from around the world. International health community's attention goes towards this mass gathering and the possibility of the development of any respiratory tract infections due to the high risk of acquisition of respiratory viruses. METHOD: We searched MEDLINE/PubMed and Scopus databases for relevant papers describing the prevalence of respiratory viruses among Hajj pilgrims...
April 16, 2018: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/29666913/comprehensive-lipid-profiling-in-the-mediterranean-mussel-mytilus-galloprovincialis-using-hyphenated-and-multidimensional-chromatography-techniques-coupled-to-mass-spectrometry-detection
#4
Paola Donato, Giuseppe Micalizzi, Marianna Oteri, Francesca Rigano, Danilo Sciarrone, Paola Dugo, Luigi Mondello
The task of lipid analysis and profiling is taking centre stage in many research fields and as a consequence, there has been an intense effort to develop suitable methodologies to discover, identify, and quantify lipids in the systems investigated. Given the high complexity and diversity of the lipidome, researchers have been challenged to afford thorough knowledge of all the lipid species in a given sample, by gathering the data obtained by complementary analytical techniques. In this research, an "omic" approach was developed to quickly fingerprint lipids in the Mediterranean mussel (Mytilus galloprovincialis), by exploiting multidimensional and hyphenated techniques...
April 17, 2018: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29666748/mass-gathering-enhanced-syndromic-surveillance-for-the-8th-micronesian-games-in-2014-pohnpei-state-federated-states-of-micronesia
#5
Paul White, Salanieta Saketa, Eliaser Johnson, Sameer V Gopalani, Eliashib Edward, Charles Loney, Alize Mercier, Tebuka Toatu, Richard Wojcik, Sheri Lewis, Damian Hoy
Pohnpei State's Division of Primary Health Care implemented enhanced surveillance for early warning and detection of disease to support the 8th Micronesian Games (the Games) in July 2014. The surveillance comprised 11 point-of-care sentinel sites around Pohnpei, Federated States of Micronesia, collecting data daily for eight syndromes using standard case definitions. Each sentinel site reported total acute care encounters, total syndrome cases and the total for each syndrome. A public health response, including epidemiological investigation and laboratory testing, followed when syndrome counts reached predetermined threshold levels...
January 2018: Western Pacific Surveillance and Response Journal: WPSAR
https://www.readbyqxmd.com/read/29664462/mass-gathering-health-considering-triggering-factors-associated-with-acute-cardiovascular-events-using-linked-registry-data
#6
Tanvir C Turin, Mohammad Al Mamun, Mohammed Almekhlafi
No abstract text is available yet for this article.
April 2018: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
https://www.readbyqxmd.com/read/29629388/a-survey-on-scientific-authenticity-of-health-information-in-iranian-popular-magazines-a-case-study
#7
Ourfa Hovsepyan, Firoozeh Zare Farashbandi, Gholamreza Askari, Akbar Hassanzadeh
BACKGROUND: The content of the mass media is a suitable tool for making changes to the society. One of the most read news in the mass media is nutritional information. The goal of this study is to assess the scientific authenticity of such information published in Iranian popular magazines. MATERIALS AND METHODS: This study is a qualitative study (content analysis) and uses bibliographic approach. A researcher-designed checklist is used as data gathering tool, and the statistical population included the messages obtained from the printed material in 173 volumes of 8 Iranian popular magazines...
2018: Journal of Education and Health Promotion
https://www.readbyqxmd.com/read/29621884/plasma-polymer-film-designs-through-the-eyes-of-tof-sims
#8
Laetitia Bernard, Patrick Rupper, Greta Faccio, Dirk Hegemann, Olivier Scholder, Manfred Heuberger, Katharina Maniura-Weber, Marianne Vandenbossche
Time-of-flight secondary ion mass spectrometry (ToF-SIMS) is increasingly used for the detailed chemical characterization of complex organic materials. Of particular interest in biointerface materials, it provides the accurate molecular information on their surface, a prerequisite for the understanding of subsequent interaction with biomaterials. Plasma polymer films are promising biointerface materials, as tuning the deposition parameters allows the control over film stability and density of surface functional groups...
April 5, 2018: Biointerphases
https://www.readbyqxmd.com/read/29621715/comparison-of-phosphodiesterase-type-v-inhibitors-use-in-eight-european-cities-through-analysis-of-urban-wastewater
#9
Ana Causanilles, Daniela Rojas Cantillano, Erik Emke, Richard Bade, Jose Antonio Baz-Lomba, Sara Castiglioni, Erika Castrignanò, Emma Gracia-Lor, Félix Hernández, Barbara Kasprzyk-Hordern, Juliet Kinyua, Ann-Kathrin McCall, Alexander L N van Nuijs, Benedek G Plósz, Pedram Ramin, Nikolaos I Rousis, Yeonsuk Ryu, Kevin V Thomas, Pim de Voogt
In this work a step forward in investigating the use of prescription drugs, namely erectile dysfunction products, at European level was taken by applying the wastewater-based epidemiology approach. 24-h composite samples of untreated wastewater were collected at the entrance of eight wastewater treatment plants serving the catchment within the cities of Bristol, Brussels, Castellón, Copenhagen, Milan, Oslo, Utrecht and Zurich. A validated analytical procedure with direct injection of filtered aliquots by liquid chromatography-tandem mass spectrometry was applied...
April 2, 2018: Environment International
https://www.readbyqxmd.com/read/29608982/stochastic-exposure-and-health-risk-assessment-of-rice-contamination-to-the-heavy-metals-in-the-market-of-iranshahr-iran
#10
Babak Djahed, Mahmoud Taghavi, Mehdi Farzadkia, Samira Norzaee, Mohammad Miri
An investigation of some heavy metals content in rice (Oryza sativa) and associated health risks was carried out for residents of Iranshahr city, Iran. Average daily rice consumption of the citizens and most widely used rice brands in the market of Iranshahr were determined using a questionnaire. Besides, the concentration of heavy metals in the gathered rice samples was measured by inductively coupled plasma mass spectrometry (ICP-MS). Monte Carlo uncertainty simulation was utilized in conducting exposure assessment and investigating the non-carcinogenic effects of the studied elements as well as the carcinogenic effect of As...
March 30, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29604471/application-of-modern-autoradiography-to-nuclear-forensic-analysis
#11
Tashi Parsons-Davis, Kim Knight, Marc Fitzgerald, Gary Stone, Lee Caldeira, Christina Ramon, Michael Kristo
Modern autoradiography techniques based on phosphorimaging technology using image plates (IPs) and digital scanning can identify heterogeneities in activity distributions and reveal material properties, serving to inform subsequent analyses. Here, we have adopted these advantages for applications in nuclear forensics, the technical analysis of radioactive or nuclear materials found outside of legal control to provide data related to provenance, production history, and trafficking route for the materials. IP autoradiography is a relatively simple, non-destructive method for sample characterization that records an image reflecting the relative intensity of alpha and beta emissions from a two-dimensional surface...
March 20, 2018: Forensic Science International
https://www.readbyqxmd.com/read/29589430/a-facile-method-and-novel-dielectric-material-using-nanoparticles-doped-thermoplastic-elastomer-composite-fabric-for-teng-applications
#12
Zhi Zhang, Ying Chen, Dereje Kebebew Debeli, Jiansheng Guo
The trends towards flexible and wearable electronic devices give rise to the attention of triboelectric nanogenerators (TENGs) which can gather tiny energy from human body motions. However, to accommodate the needs, wearable electronics are still facing challenges for choosing a better dielectric material to improve the performance and practicability. As a kind of synthetic rubber, thermoplastic elastomer (TPE) contains many advantages of lightweight, good flexibility, high tear strength and friction resistance, accompanied by good adhesion with fabrics, which is an optimal candidate of dielectric materials...
March 28, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29581564/prognostic-impact-of-early-nutritional-support-in-patients-affected-by-locally-advanced-and-metastatic-pancreatic-ductal-adenocarcinoma-undergoing-chemotherapy
#13
Ilaria Trestini, Luisa Carbognin, Isabella Sperduti, Clelia Bonaiuto, Alessandra Auriemma, Davide Melisi, Lisa Salvatore, Emilio Bria, Giampaolo Tortora
BACKGROUND/OBJECTIVES: The aim of this analysis was to determine the risk of malnutrition and the prognostic value of nutritional intervention in patients affected by pancreatic ductal adenocarcinoma (PDAC) undergoing chemotherapy. SUBJECTS/METHODS: Clinical-pathological and nutritional data were correlated with overall survival (OS) using a Cox model. Nutritional status was determined by Malnutrition Universal Screening Tool (MUST), body mass index, weight loss in the past 6 months, presence of nutrition-related symptoms, and current energy intake...
March 26, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29577222/-establishment-of-comprehensive-prediction-model-of-acute-gastrointestinal-injury-classification-of-critically-ill-patients
#14
Yan Wang, Jianrong Wang, Weiwei Liu, Guangliang Zhang
OBJECTIVE: To develop the comprehensive prediction model of acute gastrointestinal injury (AGI) grades of critically ill patients. METHODS: From April 2015 to November 2015, the binary channel gastrointestinal sounds (GIS) monitor system which has been developed and verified by the research group was used to gather and analyze the GIS of 60 consecutive critically ill patients who were admitted in Critical Care Medicine of Chinese PLA General Hospital. Also, the AGI grades (Grande I(-IIII(, the higher the level, the heavier the gastrointestinal dysfunction) were evaluated...
March 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29573730/mussel-inspired-functionalization-of-electrochemically-exfoliated-graphene-based-on-self-polymerization-of-dopamine-and-its-suppression-effect-on-the-fire-hazards-and-smoke-toxicity-of-thermoplastic-polyurethane
#15
Wei Cai, Junling Wang, Ying Pan, Wenwen Guo, Xiaowei Mu, Xiaming Feng, Bihe Yuan, Xin Wang, Yuan Hu
The suppression effect of graphene in the fire hazards and smoke toxicity of polymer composites has been seriously limited by both mass production and weak interfacial interaction. Though the electrochemical preparation provides an available approach for mass production, exfoliated graphene could not strongly bond with polar polymer chains. Herein, mussel-inspired functionalization of electrochemically exfoliated graphene was successfully processed and added into polar thermoplastic polyurethane matrix (TPU)...
March 13, 2018: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29573084/the-clinician-factor-personality-characteristics-of-clinicians-and-their-impact-upon-clinical-outcomes-in-the-management-of-children-and-adolescents-with-type-1-diabetes
#16
Fergus J Cameron, Ellyn Russel, Julia McCombe, Michele A O'Connell, Timothy Skinner
OBJECTIVE: The purpose of this study was to estimate clinician qualities that influence metabolic outcomes in youth with type 1 diabetes. RESEARCH DESIGN AND METHODS: Data were gathered over two 3 month periods in a large tertiary diabetes center (1500 patients, 8 clinicians) from patients with type 1 diabetes who received continuous care from each clinician. Data included sex, age, diabetes duration, insulin regimen, body mass index (BMI), insulin dose and episodes of severe hypoglycemia...
March 23, 2018: Pediatric Diabetes
https://www.readbyqxmd.com/read/29565932/childhood-predictors-of-adult-adiposity-findings-from-a-longitudinal-study
#17
Geraldine Fh McLeod, David M Fergusson, L John Horwood, Joseph M Boden, Frances A Carter
AIMS: The increasing prevalence of overweight and obesity has become a key challenge for New Zealand. The purpose of the present study was to examine childhood risk factors for adult adiposity in a longitudinal birth cohort. METHODS: Data were gathered from the Christchurch Health and Development Study (CHDS), a birth cohort of 1,265 children born in Christchurch in 1977. Associations were examined between socio-demographic background, perinatal factors, infant and child characteristics, family functioning/child maltreatment and adiposity at ages 30 and 35 years...
March 23, 2018: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29564501/recent-trends-in-water-analysis-triggering-future-monitoring-of-organic-micropollutants
#18
Torsten C Schmidt
Water analysis has been an important area since the beginning of analytical chemistry. The focus though has shifted substantially: from minerals and the main constituents of water in the time of Carl Remigius Fresenius to a multitude of, in particular, organic compounds at concentrations down to the sub-nanogram per liter level nowadays. This was possible only because of numerous innovations in instrumentation in recent decades, drivers of which are briefly discussed. In addition to the high demands on sensitivity, high throughput by automation and short analysis times are major requirements...
March 21, 2018: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29555221/influenza-vaccination-among-saudi-hajj-pilgrims-revealing-the-uptake-and-vaccination-barriers
#19
Mohammad Alfelali, Osamah Barasheed, Al-Mamoon Badahdah, Hamid Bokhary, Mohammed I Azeem, Turki Habeebullah, Marwan Bakarman, Atif Asghar, Robert Booy, Harunor Rashid
BACKGROUND: Hajj is the world's largest annual mass gathering that attracts two to three million Muslims from around the globe to a religious assemblage in Makkah, Saudi Arabia. The risk of acquisition and transmission of influenza among Hajj pilgrims is high. Therefore, influenza vaccination is recommended, and was monitored frequently among pilgrims from different countries. However, the vaccination uptake among Saudi pilgrims has not been assessed in recent years. OBJECTIVE: This analysis aims to evaluate influenza vaccine uptake among Saudi Hajj pilgrims, and identify the key barriers to vaccination...
March 16, 2018: Vaccine
https://www.readbyqxmd.com/read/29552999/the-gillette-stadium-experience-a-retrospective-review-of-mass-gathering-events-from-2010-to-2015
#20
Scott A Goldberg, Jeremy Maggin, Michael S Molloy, Olesya Baker, Ritu Sarin, Michael Kelleher, Kevin Mont, Adedeji Fajana, Eric Goralnick
OBJECTIVE: Mass gathering events can substantially impact public safety. Analyzing patient presentation and transport rates at various mass gathering events can help inform staffing models and improve preparedness. METHODS: A retrospective review of all patients seeking medical attention across a variety of event types at a single venue with a capacity of 68,756 from January 2010 through September 2015. RESULTS: We examined 232 events with a total of 8,260,349 attendees generating 8157 medical contacts...
March 19, 2018: Disaster Medicine and Public Health Preparedness
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