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https://www.readbyqxmd.com/read/28427648/sonochemical-synthesis-characterization-and-effects-of-temperature-power-ultrasound-and-reaction-time-on-the-morphological-properties-of-two-new-nanostructured-mercury-ii-coordination-supramolecule-compounds
#1
Payam Hayati, Ali Reza Rezvani, Ali Morsali, Daniel Ruiz Molina, Samira Geravand, Salvio Suarez-Garcia, Miguel Angel Moreno Villaecija, S García-Granda, Rafael Mendoza-Meroño, Pascal Retailleau
Two new mercury(II) coordination supramolecular compounds (CSCs) (1D and 0D), [Hg(L)(I)2]n (1) and [Hg2(L')2(SCN)2]·2H2O (2) (L=2-amino-4-methylpyridine and L'=2,6-pyridinedicarboxlic acid), have been synthesized under different experimental conditions. Micrometric crystals (bulk) or nano-sized materials have been obtained depending on using the branch tube method or sonochemical irradiation. All materials have been characterized by field emission scanning electron microscope (FESEM), scanning electron microscopy (SEM), powder X-ray diffraction (PXRD) and FT-IR spectroscopy...
July 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28425198/the-cell-adhesion-molecule-epha4-is-involved-in-circadian-clock-functions
#2
Silke Kiessling, Emma K O'Callaghan, Marlène Freyburger, Nicolas Cermakian, Valérie Mongrain
Circadian (~24 h) rhythms of cellular network plasticity in the central circadian clock, the suprachiasmatic nucleus (SCN), have been described. The neuronal network in the SCN regulates photic resetting of the circadian clock as well as stability of the circadian system during both entrained and constant conditions. EphA4, a cell adhesion molecule regulating synaptic plasticity by controlling connections of neurons and astrocytes, is expressed in the SCN. To address whether EphA4 plays a role in circadian photoreception and influences the neuronal network of the SCN, we have analysed circadian wheel-running behavior of EphA4 knockout (EphA4(-/-) ) mice under different light conditions and upon photic resetting, as well as their light-induced protein response in the SCN...
April 20, 2017: Genes, Brain, and Behavior
https://www.readbyqxmd.com/read/28423315/mir-132-212-modulates-seasonal-adaptation-and-dendritic-morphology-of-the-central-circadian-clock
#3
Lucia Mendoza-Viveros, Cheng-Kang Chiang, Jonathan L K Ong, Sara Hegazi, Arthur H Cheng, Pascale Bouchard-Cannon, Michael Fana, Christopher Lowden, Peng Zhang, Béatrice Bothorel, Matthew G Michniewicz, Stephen T Magill, Melissa M Holmes, Richard H Goodman, Valérie Simonneaux, Daniel Figeys, Hai-Ying M Cheng
The central circadian pacemaker, the suprachiasmatic nucleus (SCN), encodes day length information by mechanisms that are not well understood. Here, we report that genetic ablation of miR-132/212 alters entrainment to different day lengths and non-24 hr day-night cycles, as well as photoperiodic regulation of Period2 expression in the SCN. SCN neurons from miR-132/212-deficient mice have significantly reduced dendritic spine density, along with altered methyl CpG-binding protein (MeCP2) rhythms. In Syrian hamsters, a model seasonal rodent, day length regulates spine density on SCN neurons in a melatonin-independent manner, as well as expression of miR-132, miR-212, and their direct target, MeCP2...
April 18, 2017: Cell Reports
https://www.readbyqxmd.com/read/28421522/individual-and-combined-inhibition-of-phenol-and-thiocyanate-on-microbial-activity-of-partial-nitritation
#4
Qiong Guo, Zhi-Jian Shi, Chen-Chen Yang, Mei Huang, Jia-Li Xu, Yi-Qun Xu, Wei-Min Ni, Ren-Cun Jin
This study evaluated the individual and interactive effect of phenol and thiocyanate (SCN(-)) on partial nitritation (PN) activity using batch test and response surface methodology. The IC50 of phenol and SCN(-) on PN sludge were 5.6 and 351 mg L(-1), respectively. The PN sludge was insensitive to phenol and SCN(-) at levels lower than 1.77 and 43.3 mg L(-1), respectively. A regression model equation was developed and validated to predict the relative specific respiration rate (RSRR) of PN sludge exposed to different phenol and SCN(-) concentrations...
April 18, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28416676/dissociation-of-per1-and-bmal1-circadian-rhythms-in-the-suprachiasmatic-nucleus-in-parallel-with-behavioral-outputs
#5
Daisuke Ono, Sato Honma, Yoshihiro Nakajima, Shigeru Kuroda, Ryosuke Enoki, Ken-Ichi Honma
The temporal order of physiology and behavior in mammals is primarily regulated by the circadian pacemaker located in the hypothalamic suprachiasmatic nucleus (SCN). Taking advantage of bioluminescence reporters, we monitored the circadian rhythms of the expression of clock genes Per1 and Bmal1 in the SCN of freely moving mice and found that the rate of phase shifts induced by a single light pulse was different in the two rhythms. The Per1-luc rhythm was phase-delayed instantaneously by the light presented at the subjective evening in parallel with the activity onset of behavioral rhythm, whereas the Bmal1-ELuc rhythm was phase-delayed gradually, similar to the activity offset...
April 17, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28415687/the-prognostic-impact-of-supraclavicular-lymph-node-in-n3-iiib-stage-non-small-cell-lung-cancer-patients-treated-with-definitive-concurrent-chemo-radiotherapy
#6
Dongryul Oh, Yong Chan Ahn, Hee Chul Park, Do Hoon Lim, Jae Myoung Noh, Won Kyung Cho, Hongryull Pyo
BACKGROUND: This study aimed to investigate the prognostic impact of supraclavicular lymph node (SCN) metastasis in patients who were treated with definitive chemoradiotherapy for N3-IIIB stage non-small cell lung cancer (NSCLC). RESULTS: The 2- and 5-year overall survival (OS) rates were 57.3% and 35.7% in patients without SCN metastasis and 56.4% and 26.7% in patients with SCN metastasis, respectively. The median OS was 34 months in both groups. There was no significant difference in OS between the two groups (p = 0...
March 9, 2017: Oncotarget
https://www.readbyqxmd.com/read/28415286/dissociation-between-two-subgroups-of-the-suprachiasmatic-nucleus-affected-by-the-number-of-damped-oscillated-neurons
#7
Changgui Gu, Huijie Yang, Jos Ht Rohling
In mammals, the main clock located in the suprachiasmatic nucleus (SCN) of the brain synchronizes the body rhythms to the environmental light-dark cycle. The SCN is composed of about 2×10^{4} neurons which can be classified into three oscillatory phenotypes: self-sustained oscillators, damped oscillators, and arrhythmic neurons. Exposed to an artificial external light-dark cycle with a period of 22h instead of 24h, two subgroups of the SCN can become desynchronized (dissociated). The ventrolateral (VL) subgroup receives photic input and is entrained to the external cycle and a dorsomedial (DM) subgroup oscillates with its endogenous (i...
March 2017: Physical Review. E
https://www.readbyqxmd.com/read/28414980/fluorescence-and-circular-dichroism-studies-on-the-accessibility-of-tryptophan-residues-and-unfolding-of-a-jacalin-related-%C3%AE-d-galactose-specific-lectin-from-mulberry-morus-indica
#8
Debparna Datta, Musti J Swamy
MLGL (Mulberry Latex Galactose-specific Lectin) is an α-d-galactose binding lectin isolated from the latex of mulberry (Morus indica) tree and contains two tryptophan residues in each of its subunits. The fluorescence emission maximum of native MLGL seen at 326nm shifts to 350nm upon incubation with 6M guanidinium thiocyanate (Gdn.SCN), suggesting that the tryptophans are located inside the hydrophobic core of the protein and become fully exposed upon denaturation. Fluorescence quenching studies revealed that the neutral acrylamide exhibits the highest quenching, with ~33% of total fluorescence in the native protein being quenched at a quencher concentration of 0...
April 1, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28402374/unveiling-the-effects-of-the-in-situ-generated-arene-anion-radical-and-imine-radical-on-catecholase-like-activity-a-dft-supported-experimental-investigation
#9
Sanchari Dasgupta, Jaydeep Adhikary, Sanjib Giri, Antonio Bauza, Antonio Frontera, Debasis Das
Two new dinuclear nickel(ii) complexes namely [Ni2(L(1))2(OAc)2(H2O)2]·CH3CN (1) and [Ni2(L(2))2(SCN)2(CH3OH)2]·CH3OH (2) have been synthesized from the designed Schiff-base ligand 4-bromo-2-[(2-hydroxy-1,1-dimethyl-ethylimino)-methyl]-phenol (HL(1)) and its reduced analogue 4-bromo-2-[(2-hydroxy-1,1-dimethyl-ethylamino)-methyl]-phenol (HL(2)), respectively. Both 1 and 2 have been characterised by usual physicochemical techniques (UV-Vis, FT-IR, ESI-MS study and single crystal XRD) and their variable temperature magnetic study has been performed...
April 12, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28402052/vasopressin-casts-light-on-the-suprachiasmatic-nucleus
#10
Takahiro Tsuji, Andrew J Allchorne, Meng Zhang, Chiharu Tsuji, Vicky A Tobin, Rafael Pineda, Androniki Raftogianni, Javier E Stern, Valery Grinevich, Gareth Leng, Mike Ludwig
In all animals, the transition between night and day engages a host of physiological and behavioural rhythms. These rhythms depend not on the rods and cones of the retina, but on retinal ganglion cells (RGCs) that detect the ambient light level in the environment. These project to the suprachiasmatic nucleus (SCN) of the hypothalamus to entrain circadian rhythms that are generated within the SCN. The neuropeptide vasopressin has an important role in this entrainment. Many SCN neurons express vasopressin, and it has been assumed that the role of vasopressin in the SCN reflects the activity of these cells...
April 12, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28401917/cooperative-roles-of-the-suprachiasmatic-nucleus-central-clock-and-the-adrenal-clock-in-controlling-circadian-glucocorticoid-rhythm
#11
Sooyoung Chung, Eun Jeong Lee, Hyo Kyeong Cha, Jeongah Kim, Doyeon Kim, Gi Hoon Son, Kyungjin Kim
The mammalian circadian timing system consists of the central clock in the hypothalamic suprachiasmatic nucleus (SCN) and subsidiary peripheral clocks in other tissues. Glucocorticoids (GCs) are adrenal steroid hormones with widespread physiological effects that undergo daily oscillations. We previously demonstrated that the adrenal peripheral clock plays a pivotal role in circadian GC rhythm by driving cyclic GC biosynthesis. Here, we show that the daily rhythm in circulating GC levels is controlled by bimodal actions of central and adrenal clockwork...
April 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28401224/effect-of-ion-ligand-binding-on-ion-pairing-dynamics-studied-by-two-dimensional-infrared-spectroscopy
#12
YoungAh Kwon, Junho Lee, Sungnam Park
Cation-specific ion pairing dynamics between M(+) (M = Ag or Cu) and SCN(-) in N,N-dimethylthioformamide (DMTF) are studied by probing the nitrile (CN) stretching vibration. The SCN(-) ion, which is an ambidentate ligand, readily associates with cations to form two different types of contact ion pairs (CIPs) (i.e., M-SCN or M-NCS) and its CN stretching frequency is significantly blue-shifted so that free SCN(-) and CIPs can be well-distinguished in the FTIR spectra. Interestingly, Ag(+) ions prefer the formation of Ag-SCN in DMTF (Ag(+) + SCN(-) ⇋ Ag-SCN) but Cu(+) ions form Cu-NCS (Cu(+) + SCN(-) ⇋ Cu-NCS)...
April 12, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28395227/colorimetric-and-fluorescent-chemosensor-for-highly-selective-and-sensitive-relay-detection-of-cu-2-and-h2po4-in-aqueous-media
#13
Jun-Xia Su, Xiao-Ting Wang, Jing Chang, Gui-Yuan Wu, Hai-Ming Wang, Hong Yao, Qi Lin, You-Ming Zhang, Tai-Bao Wei
In this manuscript, a new colorimetric and fluorescent chemosensor (T) was designed and synthesized, it could successively detect Cu(2+) and H2PO4(-) in DMSO/H2O (v/v=9:1, pH=7.2) buffer solution with high selectivity and sensitivity. When added Cu(2+) ions into the solution of T, it showed a color changes from yellow to colorless, meanwhile, the green fluorescence of sensor T quenched. This recognition behavior was not affected in the presence of other cations, including Hg(2+), Ag(+), Ca(2+), Co(2+), Ni(2+), Cd(2+), Pb(2+), Zn(2+), Cr(3+), and Mg(2+) ions...
March 31, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28391739/taxonomy-for-education-and-training-in-clinical-neuropsychology-past-present-and-future
#14
Scott A Sperling, Cynthia R Cimino, Nikki H Stricker, Amy K Heffelfinger, Jennifer L Gess, Katie E Osborn, Brad L Roper
OBJECTIVE: Historically, the clinical neuropsychology training community has not clearly or consistently defined education or training opportunities. The lack of consistency has limited students' and trainees' ability to accurately assess and compare the intensity of neuropsychology-specific training provided by programs. To address these issues and produce greater 'truth in advertising' across programs, CNS, with SCN's Education Advisory Committee (EAC), ADECN, AITCN, and APPCN constructed a specialty-specific taxonomy, namely, the Taxonomy for Education and Training in Clinical Neuropsychology...
April 10, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/28389926/influence-of-molecular-characteristics-in-the-prognosis-of-methicillin-resistant-staphylococcus-aureus-prosthetic-joint-infections-beyond-the-species-and-the-antibiogram
#15
Irene Muñoz-Gallego, Jaime Lora-Tamayo, Dafne Pérez-Montarelo, Patricia Brañas, Esther Viedma, Fernando Chaves
We have explored the relationship of phenotypic (antibiogram, β-haemolysis, agr functionality, biofilm formation) and genotypic characteristics on the prognosis of 18 cases of methicillin-resistant S. aureus prosthetic joint infection (2005-2015). All isolates belonged to CC5, and had agr type II. This pilot study suggests that phage-borne genes belonging to the immune evasion cluster (chp, sak and scn) were more frequent among episodes with treatment failure (80.0 vs. 37.5%).
April 7, 2017: Infection
https://www.readbyqxmd.com/read/28387507/subtle-structural-changes-in-cu-ii-l-2mn-ii-complexes-to-induce-heterometallic-cooperative-catalytic-oxidase-activities-on-phenolic-substrates-h2l-salen-type-unsymmetrical-schiff-base
#16
Prithwish Mahapatra, Soumavo Ghosh, Sanjib Giri, Vinayak Rane, Ramakant Kadam, Michael G B Drew, Ashutosh Ghosh
A new Cu(II) complex of an asymmetrically dicondensed Schiff base (H2L = N-(2-hydroxyacetophenylidene)-N'-salicylidene-1,3-propanediamine) derived from 1,3-propanediamine, salicylaldehyde, and o-hydroxyacetophenone has been synthesized. Using this complex, [CuL] (1), as a metalloligand, two new trinuclear Cu-Mn complexes, [(CuL)2Mn(N3)(H2O)](ClO4)·H2O (2) and [(CuL)2Mn(NCS)2] (3), have been prepared. Single-crystal structural analyses reveal that complexes 2 and 3 both have the same bent trinuclear {(CuL)2Mn}(2+) structural unit in which two terminal bidentate square-planar (CuL) units are chelated to the central octahedral Mn(II) ion...
April 7, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28386619/estimation-of-conventional-c-h%C3%AF-arene-unconventional-c-h%C3%AF-chelate-and-c-h%C3%AF-thiocyanate-interactions-in-hetero-nuclear-nickel-ii-cadmium-ii-complexes-with-a-compartmental-schiff-base
#17
Sourav Roy, Michael G B Drew, Antonio Bauzá, Antonio Frontera, Shouvik Chattopadhyay
Three new heteronuclear nickel(ii)/cadmium(ii) complexes, [(SCN)(Cl)Cd(L)Ni(DMF)2] (1), [(SCN)(CH3CO2)Cd(L)Ni(CH3OH)2] (2) and [(SCN)(Cl)Cd(L)Ni(NH2CH2CH2CH2NH2)]n (3) {where H2L = N,N'-bis(3-ethoxy-salicylidene)propane-1,3-diamine is a N2O4 compartmental Schiff base}, have been synthesized and characterized. The structures of the complexes have been confirmed by single crystal X-ray diffraction studies. In each complex, nickel(ii) is placed in the inner N2O2 environment and cadmium(ii) is placed in the outer O4 compartment of the compartmental Schiff base...
April 19, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28383061/triple-cation-mixed-halide-perovskites-towards-efficient-annealing-free-and-air-stable-solar-cells-enabled-by-pb-scn-2-additive
#18
Yong Sun, Jiajun Peng, Yani Chen, Yingshan Yao, Ziqi Liang
Organo-metal halide perovskites have suffered undesirably from structural and thermal instabilities. Moreover, thermal annealing is often indispensable to the crystallization of perovskites and removal of residual solvents, which is unsuitable for scalable fabrication of flexible solar modules. Herein, we demonstrate the non-thermal annealing fabrication of a novel type of air-stable triple-cation mixed-halide perovskites, FA0.7MA0.2Cs0.1Pb(I5/6Br1/6)3 (FMC) by incorporation of Pb(SCN)2 additive. It is found that adding Pb(SCN)2 functions the same as thermal annealing process by not only improving the crystallinity and optical absorption of perovskites, but also hindering the formation of morphological defects and non-radiative recombination...
April 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28377630/katp-channels-mediate-differential-metabolic-responses-to-glucose-shortage-of-the-dorsomedial-and-ventrolateral-oscillators-in-the-central-clock
#19
Jyh-Jeen Yang, Ruo-Ciao Cheng, Pi-Cheng Cheng, Yi-Chi Wang, Rong-Chi Huang
The suprachiasmatic nucleus (SCN) central clock comprises two coupled oscillators, with light entraining the retinorecipient vasoactive intestinal peptide (VIP)-positive ventrolateral oscillator, which then entrains the arginine vasopressin (AVP)-positive dorsomedial oscillator. While glucose availability is known to alter photic entrainment, it is unclear how the SCN neurones respond to metabolic regulation and whether the two oscillators respond differently. Here we show that the ATP-sensitive K(+) (KATP) channel mediates differential responses to glucose shortage of the two oscillators...
April 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28376350/production-of-zr-89-using-sputtered-yttrium-coin-targets-89-zr-using-sputtered-yttrium-coin-targets
#20
Stacy Lee Queern, Tolulope Aramide Aweda, Adriana Vidal Fernandes Massicano, Nicholas Ashby Clanton, Retta El Sayed, Jayden Andrew Sader, Alexander Zyuzin, Suzanne Elizabeth Lapi
An increasing interest in zirconium-89 ((89)Zr) can be attributed to the isotope's half-life which is compatible with antibody imaging using positron emission tomography (PET). The goal of this work was to develop an efficient means of production for (89)Zr that provides this isotope with high radionuclidic purity and specific activity. We investigated the irradiation of yttrium sputtered niobium coins and compared the yields and separation efficiency to solid yttrium coins. The sputtered coins were irradiated with an incident beam energy of 17...
March 23, 2017: Nuclear Medicine and Biology
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