keyword
MENU ▼
Read by QxMD icon Read
search

Biomedical science

keyword
https://www.readbyqxmd.com/read/29342995/-pediatric-myeloid-neoplasms-associated-with-eosinophilia-and-platelet-derived-growth-factor-receptor-beta-gene-rearrangement-a-case-report-and-literature-review
#1
X Y Zhang, T F Liu, C W Li, Q H Li, X F Zhu
Objective: To investigate the clinical features and therapeutic strategies of childhood myeloid neoplasms associated with eosinophilia and platelet-derived growth factor receptor beta (PDGFRB) gene rearrangement. Methods: Clinical data of myeloid neoplasms associated with eosinophilia and t (1;5) (q21;q33) chromosomal translocation of PDGFRB gene rearrangement in a child hospitalized in Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences on May 2015 was collected and analyzed...
January 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29342899/smartphone-spectrometers
#2
REVIEW
Andrew J S McGonigle, Thomas C Wilkes, Tom D Pering, Jon R Willmott, Joseph M Cook, Forrest M Mims, Alfio V Parisi
Smartphones are playing an increasing role in the sciences, owing to the ubiquitous proliferation of these devices, their relatively low cost, increasing processing power and their suitability for integrated data acquisition and processing in a 'lab in a phone' capacity. There is furthermore the potential to deploy these units as nodes within Internet of Things architectures, enabling massive networked data capture. Hitherto, considerable attention has been focused on imaging applications of these devices. However, within just the last few years, another possibility has emerged: to use smartphones as a means of capturing spectra, mostly by coupling various classes of fore-optics to these units with data capture achieved using the smartphone camera...
January 14, 2018: Sensors
https://www.readbyqxmd.com/read/29341288/lipid-and-nucleic-acid-chemistries-combining-the-best-of-both-worlds-to-construct-advanced-biomaterials
#3
REVIEW
Julie Baillet, Valérie Desvergnes, Aladin Hamoud, Laurent Latxague, Philippe Barthélémy
Hybrid synthetic amphiphilic biomolecules are emerging as promising supramolecular materials for biomedical and technological applications. Herein, recent progress in the field of nucleic acid based lipids is highlighted with an emphasis on their molecular design, synthesis, supramolecular properties, physicochemical behaviors, and applications in the field of health science and technology. In the first section, the design and the study of nucleolipids are in focus and then the glyconucleolipid family is discussed...
January 17, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29338019/survey-of-checkpoints-along-the-pathway-to-diverse-biomedical-research-faculty
#4
Lindsay C Meyers, Abigail M Brown, Liane Moneta-Koehler, Roger Chalkley
There is a persistent shortage of underrepresented minority (URM) faculty who are involved in basic biomedical research at medical schools. We examined the entire training pathway of potential candidates to identify the points of greatest loss. Using a range of recent national data sources, including the National Science Foundation's Survey of Earned Doctorates and Survey of Doctoral Recipients, we analyzed the demographics of the population of interest, specifically those from URM backgrounds with an interest in biomedical sciences...
2018: PloS One
https://www.readbyqxmd.com/read/29337021/changing-physical-activity-behavior-in-people-with-multiple-sclerosis-a-systematic-review-and-meta-analysis
#5
REVIEW
Blathin Casey, Susan Coote, Sara Hayes, Stephen Gallagher
OBJECTIVE: To systematically review the literature on behavioural interventions for people with Multiple Sclerosis (pwMS) that aim to change physical activity (PA) behaviour. To explore if these interventions are clinically-effective in improving PA, theory-based and employ established behaviour change techniques (BCTs). DATA SOURCES: A systematic electronic search was conducted on databases EBSCO (including AMED, Biomedical Reference Collection: Expanded, CINHAL, MEDLINE, PsycArticles, PsycInfo), PubMed, EMBASE, and Web of Science from April 2017 to May 2017...
January 11, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29336231/a-new-and-universal-classification-system-of-skin-substitutes-inspired-by-factorial-design
#6
Evan Davison-Kotler, Vaibhav Sharma, Norbert Kang, Elena García-Gareta
The complexity of the dermal layer of skin means that damage to this section can result in permanent impairment of function. Partial or total dermal loss is a feature of deep burns and chronic wounds such as pressure sores or diabetic ulcers. The issues posed by traditional skin grafts have led to substantial research being carried out in the fields of tissue engineering and biomaterials science to develop a vast array of alternative skin substitutes. Given the large number of different materials, manufacturing methods, and techniques for implementation described for artificial skin substitutes, many classification systems have been created to simplify their categorization...
January 16, 2018: Tissue Engineering. Part B, Reviews
https://www.readbyqxmd.com/read/29333554/in-cell-nmr-from-metabolites-to-macromolecules
#7
REVIEW
G Lippens, E Cahoreau, P Millard, C Charlier, J Lopez, X Hanoulle, J C Portais
In-cell NMR of macromolecules has gained momentum over the last ten years as an approach that might bridge the branches of cell biology and structural biology. In this review, we put it in the context of earlier efforts that aimed to characterize by NMR the cellular environment of live cells and their intracellular metabolites. Although technical aspects distinguish these earlier in vivo NMR studies and the more recent in cell NMR efforts to characterize macromolecules in a cellular environment, we believe that both share major concerns ranging from sensitivity and line broadening to cell viability...
January 15, 2018: Analyst
https://www.readbyqxmd.com/read/29332786/recent-advances-and-developments-on-integrating-nanotechnology-with-chemiluminescence-assays
#8
REVIEW
Ashish Tiwari, S J Dhoble
Chemiluminescence (CL) techniques are extensively utilized for detection of analytes due to their high sensitivity, rapidity and selectivity. With the advent of nanotechnology and incorporation of the nanoparticles in the CL system has revolutionized the assays due to their unique optical and mechanical properties. Several CL-based reactions have been developed where these nanoparticle based CL sensors have evolved as excellent prospects for sensing in various analytical applications. This review article addresses the nanoparticles based CL detection system that are recently developed, the mechanisms has been summarized and the role of luminophors have been discussed...
April 1, 2018: Talanta
https://www.readbyqxmd.com/read/29328784/dna-encoded-chemical-libraries-a-selection-system-based-on-endowing-organic-compounds-with-amplifiable-information
#9
Dario Neri, Richard A Lerner
The discovery of organic ligands that bind specifically to proteins is a central problem in chemistry, biology, and the biomedical sciences. The encoding of individual organic molecules with distinctive DNA tags, serving as amplifiable identification bar codes, allows the construction and screening of combinatorial libraries of unprecedented size, thus facilitating the discovery of ligands to many different protein targets. Fundamentally, one links powers of genetics and chemical synthesis. After the initial description of DNA-encoded chemical libraries in 1992, several experimental embodiments of the technology have been reduced to practice...
January 12, 2018: Annual Review of Biochemistry
https://www.readbyqxmd.com/read/29328139/holographic-display-methods-for-volume-data-polygon-based-and-mip-based-methods
#10
Zixiang Lu, Yuji Sakamoto
Volume data are widely used in many areas, especially in biomedical science and geology. However, current visualization technologies of volume data cannot satisfy the visual requirements of humans. In this study, we propose two holographic display methods for volume data. The first method is polygon-based, and the other is maximum intensity projection (MIP)-based. Both methods are able to generate computer generated holograms of volume data. The polygon-based method can obtain various and colorful holograms, while the MIP-based method can be quickly calculated...
January 1, 2018: Applied Optics
https://www.readbyqxmd.com/read/29326013/a-cluster-of-multidrug-resistant-mycobacterium-tuberculosis-among-patients-arriving-in-europe-from-the-horn-of-africa-a-molecular-epidemiological-study
#11
Timothy M Walker, Matthias Merker, Astrid M Knoblauch, Peter Helbling, Otto D Schoch, Marieke J van der Werf, Katharina Kranzer, Lena Fiebig, Stefan Kröger, Walter Haas, Harald Hoffmann, Alexander Indra, Adrian Egli, Daniela M Cirillo, Jérôme Robert, Thomas R Rogers, Ramona Groenheit, Anne T Mengshoel, Vanessa Mathys, Marjo Haanperä, Dick van Soolingen, Stefan Niemann, Erik C Böttger, Peter M Keller
BACKGROUND: The risk of tuberculosis outbreaks among people fleeing hardship for refuge in Europe is heightened. We describe the cross-border European response to an outbreak of multidrug-resistant tuberculosis among patients from the Horn of Africa and Sudan. METHODS: On April 29 and May 30, 2016, the Swiss and German National Mycobacterial Reference Laboratories independently triggered an outbreak investigation after four patients were diagnosed with multidrug-resistant tuberculosis...
January 8, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/29325533/a-systematic-review-of-comparisons-between-protocols-or-registrations-and-full-reports-in-primary-biomedical-research
#12
Guowei Li, Luciana P F Abbade, Ikunna Nwosu, Yanling Jin, Alvin Leenus, Muhammad Maaz, Mei Wang, Meha Bhatt, Laura Zielinski, Nitika Sanger, Bianca Bantoto, Candice Luo, Ieta Shams, Hamnah Shahid, Yaping Chang, Guangwen Sun, Lawrence Mbuagbaw, Zainab Samaan, Mitchell A H Levine, Jonathan D Adachi, Lehana Thabane
BACKGROUND: Prospective study protocols and registrations can play a significant role in reducing incomplete or selective reporting of primary biomedical research, because they are pre-specified blueprints which are available for the evaluation of, and comparison with, full reports. However, inconsistencies between protocols or registrations and full reports have been frequently documented. In this systematic review, which forms part of our series on the state of reporting of primary biomedical, we aimed to survey the existing evidence of inconsistencies between protocols or registrations (i...
January 11, 2018: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/29323901/microbial-biosynthesis-of-silver-nanoparticles-in-different-culture-media
#13
Ke Luo, Samuel Jung, Kyu-Hwan Park, Young-Rok Kim
Microbial biosynthesis of metal nanoparticles has been extensively studied for the applications in biomedical sciences and engineering. However, the mechanism for their synthesis through microorganism is not completely understood. In this study, several culture media were investigated for their roles in the microbial biosynthesis of silver nanoparticles (AgNPs). The size and morphology of the synthesized AgNPs were analyzed by UV-Vis spectroscopy, FT-IR, TEM, and DLS. The results demonstrated that nutrient broth (NB) and Mueller-Hinton broth (MHB) among tested media effectively reduced silver ions to form AgNPs with different particle size and shape...
January 11, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29322916/cells-in-experimental-life-sciences-challenges-and-solution-to-the-rapid-evolution-of-knowledge
#14
EDITORIAL
Sirarat Sarntivijai, Alexander D Diehl, Yongqun He
Cell cultures used in biomedical experiments come in the form of both sample biopsy primary cells, and maintainable immortalised cell lineages. The rise of bioinformatics and high-throughput technologies has led us to the requirement of ontology representation of cell types and cell lines. The Cell Ontology (CL) and Cell Line Ontology (CLO) have long been established as reference ontologies in the OBO framework. We have compiled a series of the challenges and the proposals of solutions in this CELLS (Cells in ExperimentaL Life Sciences) thematic series that cover the grounds of standing issues and the directions, which were discussed in the First International Workshop on CELLS at the the International Conference on Biomedical Ontology (ICBO)...
December 21, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/29322912/usage-of-cell-nomenclature-in-biomedical-literature
#15
Şenay Kafkas, Sirarat Sarntivijai, Robert Hoehndorf
BACKGROUND: Cell lines and cell types are extensively studied in biomedical research yielding to a significant amount of publications each year. Identifying cell lines and cell types precisely in publications is crucial for science reproducibility and knowledge integration. There are efforts for standardisation of the cell nomenclature based on ontology development to support FAIR principles of the cell knowledge. However, it is important to analyse the usage of cell nomenclature in publications at a large scale for understanding the level of uptake of cell nomenclature in literature by scientists...
December 21, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/29322390/authentication-of-synthetic-environmental-contaminants-and-their-bio-transformation-products-in-toxicology-polychlorinated-biphenyls-as-an-example
#16
Xueshu Li, Erika B Holland, Wei Feng, Jing Zheng, Yao Dong, Isaac N Pessah, Michael W Duffel, Larry W Robertson, Hans-Joachim Lehmler
Toxicological studies use "specialty chemicals" and, thus, should assess and report both identity and degree of purity (homogeneity) of the chemicals (or toxicants) under investigation to ensure that other scientists can replicate experimental results. Although detailed reporting criteria for the synthesis and characterization of organic compounds have been established by organic chemistry journals, such criteria are inconsistently applied to the chemicals used in toxicological studies. Biologically active trace impurities may lead to incorrect conclusions about the chemical entity responsible for a biological response, which in turn may confound risk assessment...
January 10, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29316968/improving-the-interoperability-of-biomedical-ontologies-with-compound-alignments
#17
Daniela Oliveira, Catia Pesquita
BACKGROUND: Ontologies are commonly used to annotate and help process life sciences data. Although their original goal is to facilitate integration and interoperability among heterogeneous data sources, when these sources are annotated with distinct ontologies, bridging this gap can be challenging. In the last decade, ontology matching systems have been evolving and are now capable of producing high-quality mappings for life sciences ontologies, usually limited to the equivalence between two ontologies...
January 9, 2018: Journal of Biomedical Semantics
https://www.readbyqxmd.com/read/29314819/modulating-phagocytic-cell-sequestration-by-tailoring-nanoconstruct-softness
#18
Roberto Palomba, Anna Lisa Palange, Ilaria Francesca Rizzuti, Miguel Ferreira, Antonio Cervadoro, Maria Grazia Barbato, Claudio Canale, Paolo Decuzzi
The effect of nanoparticle size, shape and surface properties on cellular uptake has been extensively investigated for its basic science and translational implications. Recently, softness is emerging as a design parameter for modulating the interaction of nanoparticles with cells and the biological microenvironment. Here, circular, quadrangular and elliptical polymeric nanoconstructs of different sizes are realized with a Young's modulus ranging from ∽ 100 kPa (soft) to 10 MPa (rigid). The interaction of these nanoconstructs with professional phagocytic cells is assessed via confocal microscopy and flow cytometry analyses...
January 9, 2018: ACS Nano
https://www.readbyqxmd.com/read/29310214/fabrication-of-novel-superoxide-anion-biosensor-based-on-3d-interface-of-mussel-inspired-fe3o4-mn3-po3-2-ni-foam
#19
Qi Wang, Qian Zhou, Qicheng Zhang, Rongjia Shi, Shangshang Ma, Wenbo Zhao, Min Zhou
Preparation of high performance electrochemical biosensing interface for the sensitive and rapid detection of human metabolites is of great interest for health care and biomedical science. In this paper, based on the adhesion technique of marine mussels, we designed and prepared a novel biosensor with a micro/nano-biointerface of Fe3O4-Mn3(PO3)2@Ni foam, which offered a three dimensional (3D) living environment for real cell. The constructed biosensor with a 3D micro/nano-biointerface of Fe3O4-Mn3(PO3)2@Ni foam was characterized by scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS) and elemental mapping...
March 1, 2018: Talanta
https://www.readbyqxmd.com/read/29303691/early-preparation-and-inspiration-for-stem-careers-preliminary-report-of-the-epidemiology-challenge-randomized-intervention-2014-2015
#20
Robin Taylor Wilson, Emma Watson, Mark Kaelin, Wendy Huebner
OBJECTIVES: Early Preparation and Inspiration for Careers in the Biomedical Sciences (EPIC) is a university-high school partnership for increasing high school student interest and persistence in the biomedical sciences. EPIC includes a year-long, project-based learning intervention, the Think Like an Epidemiologist Challenge (Epi Challenge). We describe the main components of the Epi Challenge and report on short-term changes in scientific literacy and science-related motivations and beliefs...
January 2018: Public Health Reports
keyword
keyword
79272
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"