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https://www.readbyqxmd.com/read/29079727/comparison-of-dgt-with-traditional-methods-for-assessing-cadmium-bioavailability-to-brassica-chinensis-in-different-soils
#1
Yunchao Dai, Mubasher Nasir, Yulin Zhang, Haiming Wu, Honghong Guo, Jialong Lv
There is no universally accepted method for evaluating cadmium (Cd) bioavailability in soil. The diffusive gradient in thin films (DGT) technique is a promising tool, but there is considerable debate about its suitability. The ability of this technique to estimate Cd bioavailability in soils was compared with the abilities of other traditional chemical extraction techniques (soil solution, ethylene diamine tetraacetic acid (EDTA), acetic acid (HAc), calcium chloride (CaCl2), and pseudo-total Cd methods) based on a greenhouse experiment using pakchoi (Brassica chinensis) grown in 15 soils from different provinces of China...
October 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29072567/never-events-and-hospital-acquired-conditions-after-kidney-transplant
#2
Linda J Chen, Zhobin Moghadamyeghaneh, Mahmoud Alameddine, Anupam K Gupta, George W Burke, Gaetano Ciancio
INTRODUCTION: Never events (NE) and hospital-acquired conditions (HAC) after surgery have been designated as quality metrics in healthcare by the centres for Medicare and Medicaid Services (CMS). METHODS: The Nationwide Inpatient Sample (NIS) database 2002-2012 was used to identify patients underwent kidney transplant. Multivariate analysis using logistic regression was used to identify outcomes and risk factors of HAC and NE after transplantation; however, we were limited by using a retrospective database missing some important variables specified for the kidney transplant, such as some operative factors, donor factors, and cold and warm ischemia times...
November 11, 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/29065831/retention-mechanism-of-proteins-in-hydroxyapatite-chromatography-multimodal-interaction-based-protein-separations-a-model-study
#3
Daisuke Itoh, Noriko Yoshimoto, Shuichi Yamamoto
Retention mechanism of proteins in hydroxyapatite chromatography (HAC) was investigated by linear gradient elution experiments. Several mobile phase (buffer) solution strategies and solutes were evaluated in order to probe the relative contributions of two adsorption sites of hydroxyapatite (HA) particles, C-site due to Ca (metal affinity) and P-site due to PO4 (cation-exchange). When P-site was blocked, two basic proteins, lysozyme (Lys) and ribonuclease A(RNase), were not retained whereas cytochrome C(Cyt C) and lactoferrin (LF) were retained and also retention of acidic proteins became stronger as the repulsion due to P-site was eliminated...
October 24, 2017: Current Protein & Peptide Science
https://www.readbyqxmd.com/read/29064320/the-hospital-acquired-conditions-hac-reduction-program-using-cranberry-treatment-to-reduce-catheter-associated-urinary-tract-infections-and-avoid-medicare-payment-reduction-penalties
#4
T L Saitone, R J Sexton, A Sexton Ward
OBJECTIVE: The Affordable Care Act (ACA) established the Hospital-Acquired Condition (HAC) Reduction Program. The Centers for Medicare and Medicaid Services (CMS) established a total HAC scoring methodology to rank hospitals based upon their HAC performance. Hospitals that rank in the lowest quartile based on their HAC score are subject to a 1% reduction in their total Medicare reimbursements. In FY 2017, 769 hospitals incurred payment reductions totaling $430 million. This study analyzes how improvements in the rate of catheter-associated urinary tract infections (CAUTI), based on the implementation of a cranberry-treatment regimen, impact hospitals' HAC scores and likelihood of avoiding the Medicare-reimbursement penalty...
November 14, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/29039973/amendment-of-vanadium-contaminated-soil-with-soil-conditioners-a-study-based-on-pot-experiments-with-canola-plants-brassica-campestris-l
#5
Wenjie Zhang, Jianguo Jiang, Kaimin Li, Tianran Li, De' An Li, Jiaming Wang
We performed pot experiments with canola plants (Brassica campestris L.) to evaluate the effect of eight soil conditioners on the amendment of vanadium (V)-contaminated soil based on analysis of the growth of canola plants and the uptake, bioaccumulation, and translocation of heavy metals. Tested soil conditioners included polyacrylamide (PAM), sepiolite, humic acid (HAC), peat, sludge compost (SC), bentonite, lime, and fly ash. Results from the analysis of the growth of canola plants and the analysis of variance showed that the best soil conditioners for V-contaminated soil were 0...
October 17, 2017: International Journal of Phytoremediation
https://www.readbyqxmd.com/read/29038254/characterization-of-copy-number-control-of-two-haloferax-volcanii-replication-origins-using-deletion-mutants-and-haloarchaeal-artificial-chromosomes-hacs
#6
Sandy Maurer, Katharina Ludt, Jörg Soppa
Haloferax volcanii is polyploid and contains about 20 genome copies under optimal conditions. However, the chromosome copy number is highly regulated and ranges from two during phosphate starvation to more than 40 under phosphate surplus. The aim of this study was the characterization of the influence of two replication origins on the genome copy number. The origin repeats and the genes encoding Origin Recognition Complex (ORC) proteins were deleted. The core origin oriC1-orc1 (ori1) deletion mutant had a lower genome copy number and a higher fitness than the wild-type, in stark contrast to the oriC2-orc5 (ori2) deletion mutant...
October 16, 2017: Journal of Bacteriology
https://www.readbyqxmd.com/read/29036917/the-effect-of-tio%C3%A2-doped-photocatalytic-nano-additives-on-the-hydration-and-microstructure-of-portland-and-high-alumina-cements
#7
María Pérez-Nicolás, Íñigo Navarro-Blasco, José M Fernández, José Ignacio Alvarez
Mortars with two different binders (Portland cement (PC) and high alumina cement (HAC)) were modified upon the bulk incorporation of nano-structured photocatalytic additives (bare TiO₂, and TiO₂ doped with either iron (Fe-TiO₂) or vanadium (V-TiO₂)). Plastic and hardened state properties of these mortars were assessed in order to study the influence of these nano-additives. Water demand was increased, slightly by bare TiO₂ and Fe-TiO₂, and strongly by V-TiO₂, in agreement with the reduction of the particle size and the tendency to agglomerate...
October 14, 2017: Nanomaterials
https://www.readbyqxmd.com/read/29027893/hospital-acquired-conditions-predictors-and-implications-for-outcomes-following-spine-tumor-resection
#8
Nikita Lakomkin, Constantinos G Hadjipanayis
OBJECTIVE Hospital-acquired conditions (HACs) significantly compromise patient safety, and have been identified by the Centers for Medicare and Medicaid Services as events that will be associated with penalties for surgeons. The mitigation of HACs must be an important consideration during the postoperative management of patients undergoing spine tumor resection. The purpose of this study was to identify the risk factors for HACs and to characterize the relationship between HACs and other postoperative adverse events following spine tumor resection...
October 13, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29017802/big-data-and-total-hip-arthroplasty-how-do-large-databases-compare
#9
Nicholas A Bedard, Andrew J Pugely, Michael A McHugh, Nathan R Lux, Kevin J Bozic, John J Callaghan
BACKGROUND: Use of large databases for orthopedic research has become extremely popular in recent years. Each database varies in the methods used to capture data and the population it represents. The purpose of this study was to evaluate how these databases differed in reported demographics, comorbidities, and postoperative complications for primary total hip arthroplasty (THA) patients. METHODS: Primary THA patients were identified within National Surgical Quality Improvement Programs (NSQIP), Nationwide Inpatient Sample (NIS), Medicare Standard Analytic Files (MED), and Humana administrative claims database (HAC)...
September 13, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29016692/benefit-of-early-discharge-among-patients-with-low-risk-pulmonary-embolism
#10
Li Wang, Onur Baser, Phil Wells, W Frank Peacock, Craig I Coleman, Gregory J Fermann, Jeff Schein, Concetta Crivera
Clinical guidelines recommend early discharge of patients with low-risk pulmonary embolism (LRPE). This study measured the overall impact of early discharge of LRPE patients on clinical outcomes and costs in the Veterans Health Administration population. Adult patients with ≥1 inpatient diagnosis for pulmonary embolism (PE) (index date) between 10/2011-06/2015, continuous enrollment for ≥12 months pre- and 3 months post-index date were included. PE risk stratification was performed using the simplified Pulmonary Embolism Stratification Index...
2017: PloS One
https://www.readbyqxmd.com/read/28985613/preventable-complications-in-epilepsy-admissions-the-july-effect
#11
Natalie S Pierson, Daniel R Kramer, Timothy Wen, Lianne Ho, Arati Patel, Daniel Donoho, Vivek Mehta, Christianne Heck, Brian Lee, William J Mack, Charles Y Liu
BACKGROUND: Inpatient hospital stays for patients with epilepsy represent a significant burden on patients and society. Identifying factors that contribute to such costs aides in developing effective strategies to address this burden. July admissions have been associated with higher rates of complications and worse outcomes, attributed to the presence of new physicians. This study aims to evaluate whether epilepsy patients admitted in July have higher preventable complication rates and mortality than during the rest of the year...
September 20, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28956662/leptin-alone-and-in-combination-with-interleukin-1-beta-induced-cartilage-degradation-potentially-inhibited-by-epa-and-dha
#12
Thanyaluck Phitak, Kanchanit Boonmaleerat, Peraphan Pothacharoen, Dumnoensun Pruksakorn, Prachya Kongtawelert
Osteoarthritis (OA) is the most common form of arthritis. Obesity has been believed to be an important risk factor for OA development and the progression of not only load-bearing joints, but low-load-bearing joints as well. Increased leptin has been the focus of a link between obesity and OA. In this study, the effects of pathological (100ng/ml) or supra-pathological (10μg/ml) concentrations of leptin alone or in combination with IL1β on cartilage metabolisms were studied in porcine cartilage explant. The involved mechanisms were examined in human articular chondrocytes (HACs)...
September 28, 2017: Connective Tissue Research
https://www.readbyqxmd.com/read/28947974/selective-cytotoxicity-of-vanadium-complexes-on-human-pancreatic-ductal-adenocarcinoma-cell-line-by-inducing-necroptosis-apoptosis-and-mitotic-catastrophe-process
#13
Szymon Kowalski, Stanisław Hać, Dariusz Wyrzykowski, Agata Zauszkiewicz-Pawlak, Iwona Inkielewicz-Stępniak
The pancreatic cancer is the fourth leading cause of cancer-related death and characterized by one of the lowest five-year survival rate. The current therapeutic options are demonstrating minimal effectiveness, therefore studies on new potential anticancer compounds, with non-significant side effects are highly desirable. Recently, it was demonstrated that vanadium compounds, in particular organic derivatives, exhibit anticancer properties against different type of tumor as well as favorable biodistribution from a pancreatic cancer treatment perspective...
September 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/28937526/comparison-of-corneal-wetting-properties-of-different-dispersive-ophthalmic-viscosurgical-devices-an-optical-coherence-tomography-study
#14
Cagatay Karaca, Mustafa Ozkose, Metin Unlu, Duygu Gulmez Sevim, Ertugrul Mirza
PURPOSE: To compare corneal wetting performances of different dispersive ophthalmic viscosurgical devices. METHODS: Three different types of dispersive ophthalmic viscosurgical devices, hydroxypropyl methylcellulose %2 (HPMC), sodium hyaluronate %3-sodium chondroitin sulphate %4 (HACS), and sodium hyaluronate %3 (HA), were applied on corneal surfaces of 10 healthy volunteer subjects repeatedly at 3 different time points. Corneal wetting properties of the ophthalmic viscosurgical devices were compared qualitatively and quantitatively by anterior segment optical coherence tomography for 30 minutes...
September 20, 2017: Retina
https://www.readbyqxmd.com/read/28916119/safety-and-efficacy-of-glycerol-phenylbutyrate-for-management-of-urea-cycle-disorders-in-patients-aged-2months-to-2years
#15
Susan A Berry, Nicola Longo, George A Diaz, Shawn E McCandless, Wendy E Smith, Cary O Harding, Roberto Zori, Can Ficicioglu, Uta Lichter-Konecki, Beth Robinson, Jerry Vockley
INTRODUCTION: Glycerol phenylbutyrate (GPB) is approved in the US for the management of patients 2months of age and older with urea cycle disorders (UCDs) that cannot be managed with protein restriction and/or amino acid supplementation alone. Limited data exist on the use of nitrogen conjugation agents in very young patients. METHODS: Seventeen patients (15 previously on other nitrogen scavengers) with all types of UCDs aged 2months to 2years were switched to, or started, GPB...
September 8, 2017: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/28902474/electrospun-nanofibrous-meshes-cultured-with-wharton-s-jelly-stem-cell-an-alternative-for-cartilage-regeneration-without-the-need-of-growth-factors
#16
Marta Alves da Silva, Albino Martins, Ana R Costa-Pinto, Nélson Monteiro, Susana Faria, Rui L Reis, Nuno M Neves
Many efforts are being directed worldwide to the treatment of OA-focal lesions. The majority of those efforts comprise either the refinement of surgical techniques or combinations of biomaterials with various autologous cells. Herein, we tested electrospun polycaprolactone (PCL) nanofibrous meshes for cartilage tissue engineering. For that, articular chondrocytes (hACs) isolated from human osteoarthritic joints and Wharton's Jelly Stem Cells (hWJSCs) are cultured on electrospun nanofiber meshes, without adding external growth factors...
September 13, 2017: Biotechnology Journal
https://www.readbyqxmd.com/read/28900709/pretransplant-intra-arterial-liver-directed-therapy-does-not-increase-the-risk-of-hepatic-arterial-complications-in-liver-transplantation-a-single-center-10-year-experience
#17
Joseph R Kallini, Ahmed Gabr, Rehan Ali, Nadine Abouchaleh, Ahsun Riaz, Talia Baker, Laura Kulik, Juan Caicedo, Riad Salem, Robert J Lewandowski
PURPOSE: To investigate the association between pretransplant intra-arterial liver-directed therapy (IAT) for hepatocellular carcinoma (HCC) and hepatic arterial complications (HAC) in orthotopic liver transplantation (OLT) [namely hepatic artery thrombosis (HAT) and/or the need for hepatic arterial conduit]. METHODS: A total of 175 HCC patients (mean age: 60 years) underwent IAT with either transarterial chemoembolization or yttrium-90 (90Y) transarterial radioembolization prior to OLT between 2003 and 2013...
September 12, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28892708/combustion-characteristics-and-retention-emission-of-selenium-during-co-firing-of-torrefied-biomass-and-its-blends-with-high-ash-coal
#18
Habib Ullah, Guijian Liu, Balal Yousaf, Muhammad Ubaid Ali, Qumber Abbas, Chuncai Zhou
The combustion characteristics, kinetic analysis and selenium retention-emission behavior during co-combustion of high ash coal (HAC) with pine wood (PW) biomass and torrefied pine wood (TPW) were investigated through a combination of thermogravimetric analysis (TGA) and laboratory-based circulating fluidized bed combustion experiment. Improved ignition behavior and thermal reactivity of HAC were observed through the addition of a suitable proportion of biomass and torrefied. During combustion of blends, higher values of relative enrichment factors in fly ash revealed the maximum content of condensing volatile selenium on fly ash particles, and depleted level in bottom ash...
December 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28881051/heli-aza-cene-a-helical-molecular-tweezer-with-tunable-intra-and-intermolecular-charge-transfer
#19
Rajesh Kumar, Shrivats Semwal, Joyanta Choudhury, Aasheesh Srivastava
Non-planar fluorophores offer unique avenues of intra- and intermolecular energy transfer not available in their planar counterparts. We have rationally designed a molecular tweezer based on the pyridine-2,6-dicarboxamide framework having two structurally similar arms with extended π-surface. We termed this molecular tweezer as Heli(aza)cene (HAC) due to its spontaneous adoption of helical conformation stabilized by the amide and imine moieties present in it. In the helical conformation, the two arms of HAC are twisted unequally...
September 7, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28875425/initiating-human-articular-chondrocyte-re-differentiation-in-a-3d-system-after-2d-expansion
#20
Abhijith K Kudva, Frank P Luyten, Jennifer Patterson
Cartilage damage affects a large population via acute and chronic injury and disease. Since native cartilage does not self-renew, cartilage tissue engineering has gained traction as a potential treatment. However, a limiting factor is that the primary cell type in cartilage, the articular chondrocyte, tends to de-differentiate when grown on 2D surfaces for in vitro expansion. Thus, 3D systems are being developed and used to counter this loss of chondrogenic capabilities. We hypothesize that a 3D matrix that can be remodeled may be more supportive of the chondrogenic phenotype of encapsulated articular chondrocytes than a 2D surface and may allow for the re-differentiation of chondrocytes after 2D expansion...
September 5, 2017: Journal of Materials Science. Materials in Medicine
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