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REVIEW
Antonino Lo Giudice, Salvatore La Rosa, Vincenzo Ronsivalle, Gaetano Isola, Marco Cicciù, Giulio Alessandri-Bonetti, Rosalia Leonardi
Obstructive sleep apnea (OSA) syndrome is characterized by repeated airway collapse during sleep. It determines cardiovascular, pulmonary, and neurocognitive consequences and is associated with several daytime and nighttime symptoms that influence the patient's quality of life. The contribution of the dental specialist in the clinical management of OSA patients entails participating in the screening process as diagnostic sentinels and providing adequate treatment using mandibular advancement devices (MADs)...
2024: International Journal of Dentistry
#2
JOURNAL ARTICLE
Ilaria Cicalini, Antonio Maria Chiarelli, Piero Chiacchiaretta, David Perpetuini, Consuelo Rosa, Domenico Mastrodicasa, Martina d'Annibale, Stefano Trebeschi, Francesco Lorenzo Serafini, Giulio Cocco, Marco Narciso, Antonio Corvino, Sebastiano Cinalli, Domenico Genovesi, Paola Lanuti, Silvia Valentinuzzi, Damiana Pieragostino, Davide Brocco, Regina G H Beets-Tan, Nicola Tinari, Stefano L Sensi, Liborio Stuppia, Piero Del Boccio, Massimo Caulo, Andrea Delli Pizzi
Treatment response assessment of rectal cancer patients is a critical component of personalized cancer care and it allows to identify suitable candidates for organ-preserving strategies. This pilot study employed a novel multi-omics approach combining MRI-based radiomic features and untargeted metabolomics to infer treatment response at staging. The metabolic signature highlighted how tumor cell viability is predictively down-regulated, while the response to oxidative stress was up-regulated in responder patients, showing significantly reduced oxoproline values at baseline compared to non-responder patients (p-value < 10-4 )...
March 27, 2024: La Radiologia Medica
#3
JOURNAL ARTICLE
Giulio La Rosa, Carlos Morillo, Jorge G Quintanilla, Adelina Doltra, Lluis Mont, Moisés Rodríguez-Mañero, Andrea Sarkosy, José Luis Merino, David Vivas, Tomás Datino, David Calvo, Nicasio Pérez-Castellano, Julián Pérez-Villacastín, Laurent Fauchier, Gregory Lip, Stéphane N Hatem, José Jalife, Laura Sanchis, Francisco Marín, David Filgueiras-Rama
Atrial fibrillation (AF) causes progressive structural and electrical changes in the atria that can be summarized within the general concept of atrial remodeling. In parallel, other clinical characteristics and comorbidities may also affect atrial tissue properties and make the atria susceptible to AF initiation and its long-term persistence. Overall, pathological atrial changes lead to atrial cardiomyopathy with important implications for rhythm control. Although there is general agreement on the role of the atrial substrate for successful rhythm control in AF, the current classification oversimplifies clinical management...
February 28, 2024: Revista Española de Cardiología
#4
JOURNAL ARTICLE
Michele Equestre, Cinzia Marcantonio, Nadia Marascio, Federica Centofanti, Antonio Martina, Matteo Simeoni, Elisabetta Suffredini, Giuseppina La Rosa, Giusy Bonanno Ferraro, Pamela Mancini, Carolina Veneri, Giovanni Matera, Angela Quirino, Angela Costantino, Stefania Taffon, Elena Tritarelli, Carmelo Campanella, Giulio Pisani, Roberto Nisini, Enea Spada, Paola Verde, Anna Rita Ciccaglione, Roberto Bruni
We investigated SARS-CoV-2 variants circulating, from November 2020 to March 2022, among military and civilian personnel at an Air Force airport in Italy in order to classify viral isolates in a potential hotspot for virus spread. Positive samples were subjected to Next-Generation Sequencing (NGS) of the whole viral genome and Sanger sequencing of the spike coding region. Phylogenetic analysis classified viral isolates and traced their evolutionary relationships. Clusters were identified using 70% cut-off. Sequencing methods yielded comparable results in terms of variant classification...
November 5, 2023: Microorganisms
#5
JOURNAL ARTICLE
Daniel Enríquez-Vázquez, Jorge G Quintanilla, Alba García-Escolano, Marinela Couselo-Seijas, Ana Simón-Chica, Peter Lee, José Manuel Alfonso-Almazán, Patricia Mahía, Andrés Redondo-Rodríguez, Javier Modrego, Adriana Ortega-Hernández, Pedro Marcos-Alberca, Ricardo Magni, Enrique Calvo, Rubén Gómez-Gordo, Ping Yan, Giulio La Rosa, José Bustamante-Madrión, Carlos Nicolás Pérez-García, F Javier Martín-Sánchez, David Calvo, Jesús M de la Hera, María Jesús García-Torrent, Álvaro García-Osuna, Jordi Ordonez-Llanos, Jesús Vázquez, Julián Pérez-Villacastín, Nicasio Pérez-Castellano, Leslie M Loew, Javier Sánchez-González, Dulcenombre Gómez-Garre, David Filgueiras-Rama
Electromechanical characterization during atrial fibrillation (AF) remains a significant gap in the understanding of AF-related atrial myopathy. This study reports mechanistic insights into the electromechanical remodeling process associated with AF progression and further demonstrates its prognostic value in the clinic. In pigs, sequential electromechanical assessment during AF progression shows a progressive decrease in mechanical activity and early dissociation from its electrical counterpart. Atrial tissue samples from animals with AF reveal an abnormal increase in cardiomyocytes death and alterations in calcium handling proteins...
August 4, 2023: Nature Communications
#6
JOURNAL ARTICLE
Damiano Baldassarre, Licia Iacoviello, Roberta Baetta, Maria Carla Roncaglioni, Gianluigi Condorelli, Giuseppe Remuzzi, Gianfranco Gensini, Luigi Frati, Walter Ricciardi, Pier Giulio Conaldi, Antonio Uccelli, Fabio Blandini, Silvano Bosari, Giovanni Scambia, Massimo Fini, Antonio Di Malta, Mauro Amato, Fabrizio Veglia, Alice Bonomi, Catherine Klersy, Francesca Colazzo, Martino Pengo, Francesca Gorini, Luciana Auteri, Giuseppe Ferrante, Marta Baviera, Giuseppe Ambrosio, Alberico Catapano, Alessandro Gialluisi, Alexis Elias Malavazos, Serenella Castelvecchio, Massimiliano Marco Corsi-Romanelli, Rosanna Cardani, Maria Teresa La Rovere, Valentina Agnese, Bianca Pane, Daniele Prati, Laura Spinardi, Giovanna Liuzzo, Eloisa Arbustini, Maurizio Volterrani, Marco Visconti, José Pablo Werba, Stefano Genovese, Grzegorz Bilo, Cecilia Invitti, Anna Di Blasio, Carolina Lombardi, Andrea Faini, Debora Rosa, Luisa Ojeda-Fernández, Andreana Foresta, Amalia De Curtis, Augusto Di Castelnuovo, Simonetta Scalvini, Antonia Pierobon, Alessandra Gorini, Luca Valenti, Livio Luzi, Annarosa Racca, Manuela Bandi, Elena Tremoli, Lorenzo Menicanti, Gianfranco Parati, Giulio Pompilio
INTRODUCTION: Prevention of cardiovascular disease (CVD) is of key importance in reducing morbidity, disability and mortality worldwide. Observational studies suggest that digital health interventions can be an effective strategy to reduce cardiovascular (CV) risk. However, evidence from large randomised clinical trials is lacking. METHODS AND ANALYSIS: The CV-PREVITAL study is a multicentre, prospective, randomised, controlled, open-label interventional trial designed to compare the effectiveness of an educational and motivational mobile health (mHealth) intervention versus usual care in reducing CV risk...
July 14, 2023: BMJ Open
#7
JOURNAL ARTICLE
Jens D Lundgren, Abdel G Babiker, Shweta Sharma, Birgit Grund, Andrew N Phillips, Gail Matthews, Virginia L Kan, Bitten Aagaard, Inka Abo, Beverly Alston, Alejandro Arenas-Pinto, Anchalee Avihingsanon, Sharlaa Badal-Faesen, Carlos Brites, Cate Carey, Jorge Casseb, Amanda Clarke, Simon Collins, Giulio Maria Corbelli, Sounkalo Dao, Eileen T Denning, Sean Emery, Nnakelu Eriobu, Eric Florence, Hansjakob Furrer, Gerd Fätkenheuer, Jan Gerstoft, Magnus Gisslén, Katharine Goodall, Keith Henry, Andrzej Horban, Jennifer Hoy, Fleur Hudson, Raja Iskandar Shah Raja Azwa, Eynat Kedem, Anthony Kelleher, Cissy Kityo, Karin Klingman, Alberto La Rosa, Nicolas Leturque, Alan R Lifson, Marcelo Losso, Joseph Lutaakome, Juan Sierra Madero, Patrick Mallon, Kamal Mansinho, Kamal Marhoum El Filali, Jean-Michel Molina, Daniel D Murray, Kumarasamy Nagalingeswaran, Silvia Nozza, Vidar Ormaasen, Roger Paredes, Luiz Carlos Peireira, Sandy Pillay, Mark N Polizzotto, Dorthe Raben, Armin Rieger, Adriana Sanchez, Mauro Schechter, Dalibor Sedlacek, Therese Staub, Giota Touloumi, Melissa Turner, Jose Valdez Madruga, Michael Vjecha, Marcelo Wolff, Robin Wood, Kai Zilmer, H Clifford Lane, James D Neaton
BACKGROUND: For people with HIV and CD4+ counts >500 cells/mm3 , early initiation of antiretroviral therapy (ART) reduces serious AIDS and serious non-AIDS (SNA) risk compared with deferral of treatment until CD4+ counts are <350 cells/mm3 . Whether excess risk of AIDS and SNA persists once ART is initiated for those who defer treatment is uncertain. METHODS: The Strategic Timing of AntiRetroviral Treatment (START) trial, as previously reported, randomly assigned 4684 ART-naive HIV-positive adults with CD4+ counts ...
March 2023: NEJM Evid
#8
JOURNAL ARTICLE
Dick Schijven, Merel C Postema, Masaki Fukunaga, Junya Matsumoto, Kenichiro Miura, Sonja M C de Zwarte, Neeltje E M van Haren, Wiepke Cahn, Hilleke E Hulshoff Pol, René S Kahn, Rosa Ayesa-Arriola, Víctor Ortiz-García de la Foz, Diana Tordesillas-Gutierrez, Javier Vázquez-Bourgon, Benedicto Crespo-Facorro, Dag Alnæs, Andreas Dahl, Lars T Westlye, Ingrid Agartz, Ole A Andreassen, Erik G Jönsson, Peter Kochunov, Jason M Bruggemann, Stanley V Catts, Patricia T Michie, Bryan J Mowry, Yann Quidé, Paul E Rasser, Ulrich Schall, Rodney J Scott, Vaughan J Carr, Melissa J Green, Frans A Henskens, Carmel M Loughland, Christos Pantelis, Cynthia Shannon Weickert, Thomas W Weickert, Lieuwe de Haan, Katharina Brosch, Julia-Katharina Pfarr, Kai G Ringwald, Frederike Stein, Andreas Jansen, Tilo T J Kircher, Igor Nenadić, Bernd Krämer, Oliver Gruber, Theodore D Satterthwaite, Juan Bustillo, Daniel H Mathalon, Adrian Preda, Vince D Calhoun, Judith M Ford, Steven G Potkin, Jingxu Chen, Yunlong Tan, Zhiren Wang, Hong Xiang, Fengmei Fan, Fabio Bernardoni, Stefan Ehrlich, Paola Fuentes-Claramonte, Maria Angeles Garcia-Leon, Amalia Guerrero-Pedraza, Raymond Salvador, Salvador Sarró, Edith Pomarol-Clotet, Valentina Ciullo, Fabrizio Piras, Daniela Vecchio, Nerisa Banaj, Gianfranco Spalletta, Stijn Michielse, Therese van Amelsvoort, Erin W Dickie, Aristotle N Voineskos, Kang Sim, Simone Ciufolini, Paola Dazzan, Robin M Murray, Woo-Sung Kim, Young-Chul Chung, Christina Andreou, André Schmidt, Stefan Borgwardt, Andrew M McIntosh, Heather C Whalley, Stephen M Lawrie, Stefan du Plessis, Hilmar K Luckhoff, Freda Scheffler, Robin Emsley, Dominik Grotegerd, Rebekka Lencer, Udo Dannlowski, Jesse T Edmond, Kelly Rootes-Murdy, Julia M Stephen, Andrew R Mayer, Linda A Antonucci, Leonardo Fazio, Giulio Pergola, Alessandro Bertolino, Covadonga M Díaz-Caneja, Joost Janssen, Noemi G Lois, Celso Arango, Alexander S Tomyshev, Irina Lebedeva, Simon Cervenka, Carl M Sellgren, Foivos Georgiadis, Matthias Kirschner, Stefan Kaiser, Tomas Hajek, Antonin Skoch, Filip Spaniel, Minah Kim, Yoo Bin Kwak, Sanghoon Oh, Jun Soo Kwon, Anthony James, Geor Bakker, Christian Knöchel, Michael Stäblein, Viola Oertel, Anne Uhlmann, Fleur M Howells, Dan J Stein, Henk S Temmingh, Ana M Diaz-Zuluaga, Julian A Pineda-Zapata, Carlos López-Jaramillo, Stephanie Homan, Ellen Ji, Werner Surbeck, Philipp Homan, Simon E Fisher, Barbara Franke, David C Glahn, Ruben C Gur, Ryota Hashimoto, Neda Jahanshad, Eileen Luders, Sarah E Medland, Paul M Thompson, Jessica A Turner, Theo G M van Erp, Clyde Francks
Left-right asymmetry is an important organizing feature of the healthy brain that may be altered in schizophrenia, but most studies have used relatively small samples and heterogeneous approaches, resulting in equivocal findings. We carried out the largest case-control study of structural brain asymmetries in schizophrenia, with MRI data from 5,080 affected individuals and 6,015 controls across 46 datasets, using a single image analysis protocol. Asymmetry indexes were calculated for global and regional cortical thickness, surface area, and subcortical volume measures...
April 4, 2023: Proceedings of the National Academy of Sciences of the United States of America
#9
JOURNAL ARTICLE
Constantinos Constantinides, Laura K M Han, Clara Alloza, Linda Antonella Antonucci, Celso Arango, Rosa Ayesa-Arriola, Nerisa Banaj, Alessandro Bertolino, Stefan Borgwardt, Jason Bruggemann, Juan Bustillo, Oleg Bykhovski, Vince Calhoun, Vaughan Carr, Stanley Catts, Young-Chul Chung, Benedicto Crespo-Facorro, Covadonga M Díaz-Caneja, Gary Donohoe, Stefan Du Plessis, Jesse Edmond, Stefan Ehrlich, Robin Emsley, Lisa T Eyler, Paola Fuentes-Claramonte, Foivos Georgiadis, Melissa Green, Amalia Guerrero-Pedraza, Minji Ha, Tim Hahn, Frans A Henskens, Laurena Holleran, Stephanie Homan, Philipp Homan, Neda Jahanshad, Joost Janssen, Ellen Ji, Stefan Kaiser, Vasily Kaleda, Minah Kim, Woo-Sung Kim, Matthias Kirschner, Peter Kochunov, Yoo Bin Kwak, Jun Soo Kwon, Irina Lebedeva, Jingyu Liu, Patricia Mitchie, Stijn Michielse, David Mothersill, Bryan Mowry, Víctor Ortiz-García de la Foz, Christos Pantelis, Giulio Pergola, Fabrizio Piras, Edith Pomarol-Clotet, Adrian Preda, Yann Quidé, Paul E Rasser, Kelly Rootes-Murdy, Raymond Salvador, Marina Sangiuliano, Salvador Sarró, Ulrich Schall, André Schmidt, Rodney J Scott, Pierluigi Selvaggi, Kang Sim, Antonin Skoch, Gianfranco Spalletta, Filip Spaniel, Sophia I Thomopoulos, David Tomecek, Alexander S Tomyshev, Diana Tordesillas-Gutiérrez, Therese van Amelsvoort, Javier Vázquez-Bourgon, Daniela Vecchio, Aristotle Voineskos, Cynthia S Weickert, Thomas Weickert, Paul M Thompson, Lianne Schmaal, Theo G M van Erp, Jessica Turner, James H Cole, Danai Dima, Esther Walton
Schizophrenia (SZ) is associated with an increased risk of life-long cognitive impairments, age-related chronic disease, and premature mortality. We investigated evidence for advanced brain ageing in adult SZ patients, and whether this was associated with clinical characteristics in a prospective meta-analytic study conducted by the ENIGMA Schizophrenia Working Group. The study included data from 26 cohorts worldwide, with a total of 2803 SZ patients (mean age 34.2 years; range 18-72 years; 67% male) and 2598 healthy controls (mean age 33...
December 9, 2022: Molecular Psychiatry
#10
JOURNAL ARTICLE
Giulio La Rosa, Gemma Pelargonio, Maria Lucia Narducci, Gaetano Pinnacchio, Gianluigi Bencardino, Francesco Perna, Federico Follesa, Leonarda Galiuto, Filippo Crea
INTRODUCTION AND OBJECTIVES: The clinical value of electrocardiogram (ECG) repolarization parameters associated with ventricular arrhythmias (VAs) in tako-tsubo syndrome is still under debate. We aimed to evaluate ECG predictors of subacute VAs, defined as those occurring after the first 48 hours from admission. METHODS: This single-center observational study enrolled patients admitted to the cardiology department between 2012 and 2018 with a confirmed diagnosis of tako-tsubo syndrome...
December 6, 2022: Revista Española de Cardiología
#11
JOURNAL ARTICLE
Michela Puxeddu, Jianchao Wu, Ruoli Bai, Michele D'Ambrosio, Marianna Nalli, Antonio Coluccia, Simone Manetto, Alessia Ciogli, Domiziana Masci, Andrea Urbani, Cinzia Fionda, Sonia Coni, Rosa Bordone, Gianluca Canettieri, Chiara Bigogno, Giulio Dondio, Ernest Hamel, Te Liu, Romano Silvestri, Giuseppe La Regina
We synthesized new aroyl diheterocyclic pyrrole (ARDHEP) 15 that exhibited the hallmarks of ferroptosis. Compound 15 strongly inhibited U-87 MG, OVCAR-3, and MCF-7 cancer cells, induced an increase of cleaved PARP, but was not toxic for normal human primary T lymphocytes at 0.1 μM. Analysis of the levels of lactoperoxidase, malondialdehyde, lactic acid, total glutathione, and ATP suggested that the in vivo inhibition of cancer cell proliferation by 15 went through stimulation of oxidative stress injury and Fe2+ accumulation...
November 17, 2022: Journal of Medicinal Chemistry
#12
JOURNAL ARTICLE
Juanita A Haagsma, Periklis Charalampous, Filippo Ariani, Anne Gallay, Kim Moesgaard Iburg, Evangelia Nena, Che Henry Ngwa, Alexander Rommel, Ausra Zelviene, Kedir Hussein Abegaz, Hanadi Al Hamad, Luciana Albano, Catalina Liliana Andrei, Tudorel Andrei, Ippazio Cosimo Antonazzo, Olatunde Aremu, Ashokan Arumugam, Alok Atreya, Avinash Aujayeb, Jose Luis Ayuso-Mateos, Luchuo Engelbert Bain, Maciej Banach, Till Winfried Bärnighausen, Francesco Barone-Adesi, Massimiliano Beghi, Derrick A Bennett, Akshaya S Bhagavathula, Félix Carvalho, Giulio Castelpietra, Ledda Caterina, Joht Singh Chandan, Rosa A S Couto, Natália Cruz-Martins, Giovanni Damiani, Anna Dastiridou, Andreas K Demetriades, Diana Dias-da-Silva, Adeniyi Francis Fagbamigbe, Seyed-Mohammad Fereshtehnejad, Eduarda Fernandes, Pietro Ferrara, Florian Fischer, Urbano Fra Paleo, Silvia Ghirini, James C Glasbey, Ionela-Roxana Glavan, Nelson G M Gomes, Michal Grivna, Netanja I Harlianto, Josep Maria Haro, M Tasdik Hasan, Sorin Hostiuc, Ivo Iavicoli, Milena D Ilic, Irena M Ilic, Mihajlo Jakovljevic, Jost B Jonas, Jacek Jerzy Jozwiak, Mikk Jürisson, Joonas H Kauppila, Gbenga A Kayode, Moien A B Khan, Adnan Kisa, Sezer Kisa, Ai Koyanagi, Manasi Kumar, Om P Kurmi, Carlo La-Vecchia, Demetris Lamnisos, Savita Lasrado, Paolo Lauriola, Shai Linn, Joana A Loureiro, Raimundas Lunevicius, Aurea Madureira-Carvalho, Enkeleint A Mechili, Azeem Majeed, Ritesh G Menezes, Alexios-Fotios A Mentis, Atte Meretoja, Tomislav Mestrovic, Tomasz Miazgowski, Bartosz Miazgowski, Andreea Mirica, Mariam Molokhia, Shafiu Mohammed, Lorenzo Monasta, Francesk Mulita, Mukhammad David Naimzada, Ionut Negoi, Subas Neupane, Bogdan Oancea, Hans Orru, Adrian Otoiu, Nikita Otstavnov, Stanislav S Otstavnov, Alicia Padron-Monedero, Songhomitra Panda-Jonas, Shahina Pardhan, Jay Patel, Paolo Pedersini, Marina Pinheiro, Ivo Rakovac, Chythra R Rao, Salman Rawaf, David Laith Rawaf, Violet Rodrigues, Luca Ronfani, Dominic Sagoe, Francesco Sanmarchi, Milena M Santric-Milicevic, Brijesh Sathian, Aziz Sheikh, Rahman Shiri, Siddharudha Shivalli, Inga Dora Sigfusdottir, Rannveig Sigurvinsdottir, Valentin Yurievich Skryabin, Anna Aleksandrovna Skryabina, Catalin-Gabriel Smarandache, Bogdan Socea, Raúl A R C Sousa, Paschalis Steiropoulos, Rafael Tabarés-Seisdedos, Marcos Roberto Tovani-Palone, Fimka Tozija, Sarah Van de Velde, Tommi Juhani Vasankari, Massimiliano Veroux, Francesco S Violante, Vasiliy Vlassov, Yanzhong Wang, Ali Yadollahpour, Sanni Yaya, Mikhail Sergeevich Zastrozhin, Anasthasia Zastrozhina, Suzanne Polinder, Marek Majdan
BACKGROUND: Injury remains a major concern to public health in the European region. Previous iterations of the Global Burden of Disease (GBD) study showed wide variation in injury death and disability adjusted life year (DALY) rates across Europe, indicating injury inequality gaps between sub-regions and countries. The objectives of this study were to: 1) compare GBD 2019 estimates on injury mortality and DALYs across European sub-regions and countries by cause-of-injury category and sex; 2) examine changes in injury DALY rates over a 20 year-period by cause-of-injury category, sub-region and country; and 3) assess inequalities in injury mortality and DALY rates across the countries...
May 20, 2022: Archives of Public Health, Archives Belges de Santé Publique
#13
JOURNAL ARTICLE
Jannis Müller, Francesco La Rosa, Jeremy Beaumont, Charidimos Tsagkas, Reza Rahmanzadeh, Matthias Weigel, Meritxell Bach Cuadra, Giulio Gambarota, Cristina Granziera
OBJECTIVE: Cortical lesions are common in multiple sclerosis (MS), but their visualization is challenging on conventional magnetic resonance imaging. The uniform image derived from magnetization prepared 2 rapid acquisition gradient echoes (MP2RAGE uni ) detects cortical lesions with a similar rate as the criterion standard sequence, double inversion recovery. Fluid and white matter suppression (FLAWS) provides multiple reconstructed contrasts acquired during a single acquisition. These contrasts include FLAWS minimum image (FLAWS min ), which provides an exquisite sensitivity to the gray matter signal and therefore may facilitate cortical lesion identification, as well as high contrast FLAWS (FLAWS hco ), which gives a contrast that is similar to one of MP2RAGE uni ...
September 1, 2022: Investigative Radiology
#14
JOURNAL ARTICLE
Héctor J Rodríguez-Casanovas, Manuel De la Rosa, Yesit Bello-Lemus, Giulio Rasperini, Antonio J Acosta-Hoyos
BACKGROUND: Saliva of patients with COVID-19 has a high SARS-CoV-2 viral load. The risk of spreading the virus is not insignificant, and procedures for reducing viral loads in the oral cavity have been proposed. Little research to date has been performed on the effect of mouthwashes on the SARS-CoV-2 virus, and some of their mechanisms of action remain unknown. METHODS: SARS-CoV-2 positive nasopharyngeal swabs measured by RT-PCR were used for virucidal activity in a 1:1 ratio, with an incubation time of 1 min...
December 30, 2021: Healthcare (Basel, Switzerland)
#15
REVIEW
Antonio Granata, Rosario Maccarrone, Sandra La Rosa, Giulio Distefano, Massimiliano Anzaldi, Antonio Di Mauro, Giuseppe Leonardi, Francesco Pesce, Francesco Amico, Loreto Gesualdo
Optimal glycemic control in diabetic patients remains a difficult goal to achieve. Hypoglycemia, nausea and weight gain can compromise the patients' adherence to antidiabetic therapy over time. GLP-1 receptor agonists have been shown to improve glycemic control and reduce the incidence of side effects both when used in monotherapy and in combination with other hypoglycemic drugs. The growing interest of nephrologists in GLP-1 receptor agonists derives from numerous studies showing that not only they positively affect traditional cardiovascular risk factors, but also exert a protective effect on renal function regardless of their hypoglycemic effects, thus delaying the development and progression of diabetic nephropathy...
December 16, 2021: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
#16
JOURNAL ARTICLE
Fabio Anastasio, Tommaso LA Macchia, Giulio Rossi, Marco D'Abbondanza, Rosa Curcio, Gaetano Vaudo, Giacomo Pucci
BACKGROUND: Mid- and long-term sequelae of COVID-19 on cardiorespiratory fitness are unknown. Aim of the study was to assess the mid-term impact of mild-moderate COVID-19 on cardiorespiratory fitness evaluated by cardiopulmonary exercise testing (CPET) in élite athletes. METHODS: 13 elite cross-country skiers with previous mild-moderate COVID-19 symptoms underwent CPET before resuming seasonal training (COVID athletes). 13 élite detrained cross-country skiers, matched for principal confounding factors, were taken as controls (control group)...
November 10, 2021: Journal of Sports Medicine and Physical Fitness
#17
LETTER
Desiderio Passali, Rosario La Rosa, Giulio Cesare Passali, Giorgio Ciprandi
N/A.
November 3, 2021: Acta Bio-medica: Atenei Parmensis
#18
JOURNAL ARTICLE
Giovanni LA Rosa, Antonio Frizziero, Giulio S Roi
No abstract text is available yet for this article.
September 9, 2021: European Journal of Physical and Rehabilitation Medicine
#19
Franco Pepe, Claudia Mininni, Elisabetta Zambrotta, Gabriele Pepe, Valeria La Rosa, Rosario La Rosa, Giulio Insalaco, Morena Maria Monteleone
Although pregnant neurofibromatosis or HIV patient established a high-risk group, this report demonstrated that a careful planning and widespread valuations should be associated with a favorable prognosis for both mother and newborn.
August 2021: Clinical Case Reports
#20
JOURNAL ARTICLE
Giuseppina Facco, Francesco Bennardello, Francesco Fiorin, Claudia Galassi, Chiara Monagheddu, Pierluigi Berti
BACKGROUND: In Italy, as in many developed countries, a decline in blood component (BC) consumption, especially red blood cells (RBC), has been described, but not studied at a national level. We, therefore, designed a nationwide survey to determine the main features of BC recipients and obtain a picture of the clinical use of BC for the first time in Italy, in order to understand BC demands better and identify specific fields in which to apply Patient Blood Management (PBM). MATERIAL AND METHODS: A nationwide survey of all Italian Blood Establishments working as Hospital Blood Banks (HBB) was performed...
September 2021: Blood Transfusion
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