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https://www.readbyqxmd.com/read/27923256/-fostering-resilience-while-waiting-for-psychotherapy-evaluation-of-a-group-intervention-in-an-outpatient-care-setting
#1
Philipp Victor, Tobias Teismann, Ulrike Willutzki
Background: High untreated prevalence of mental disorders and long waiting lists for psychotherapy at the same time call for innovative intervention concepts. The positive brief intervention "Personal Model of Resilience" 1 is offered as group training and evaluated for the first time in a naturalistic clinical setting. Method: In a pre-post-design data from 84 wait-list patients are analysed via intention-to-treat (n=84) and completer analysis at 6-week-follow-up (n=54). Results: Repeated measures ANOVAs demonstrate significant improvements in psychopathology, incongruence and self-esteem...
December 2016: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/27923236/the-effect-of-head-positioning-and-head-tilting-on-the-incidence-of-intraventricular-hemorrhage-in-very-preterm-infants-a-systematic-review
#2
Karen A de Bijl-Marcus, Annemieke J Brouwer, Linda S de Vries, Gerda van Wezel-Meijler
BACKGROUND: Despite advances in neonatal intensive care, germinal matrix-intraventricular hemorrhage (GMH-IVH) remains a frequent, serious complication of premature birth. Neutral head position and head tilting have been suggested to reduce the risk of GMH-IVH in preterm infants during the first 72 h of life. OBJECTIVE: The aim of this study was to provide a systematic review of the effect of neutral head positioning and head tilting on the incidence of GMH-IVH in very preterm infants (gestational age ≤30 weeks)...
December 7, 2016: Neonatology
https://www.readbyqxmd.com/read/27923227/optimal-role-of-the-nephrologist-in-the-intensive-care-unit
#3
D J Askenazi, Michael Heung, Michael J Connor, Rajit K Basu, Jorge Cerdá, Kent Doi, Jay L Koyner, Azra Bihorac, Ladan Golestaneh, Anitha Vijayan, Mark D Okusa, Sarah Faubel
As advances in Critical Care Medicine continue, critically ill patients are surviving despite the severity of their illness. The incidence of acute kidney injury (AKI) has increased, and its impact on clinical outcomes as well as medical expenditures has been established. The role, indications and technological advancements of renal replacement therapy (RRT) have evolved, allowing more effective therapies with less complications. With these changes, Critical Care Nephrology has become an established specialty, and ongoing collaborations between critical care physicians and nephrologist have improved education of multi-disciplinary team members and patient care in the ICU...
December 3, 2016: Blood Purification
https://www.readbyqxmd.com/read/27923217/effect-of-direct-ligament-repair-and-tenodesis-reconstruction-on-simulated-subtalar-joint-instability
#4
Julie Choisne, Matthew C Hoch, Ian Alexander, Stacie I Ringleb
BACKGROUND: Subtalar instability is associated with up to 80% of patients presenting with chronic ankle instability but is often not considered in the diagnosis or treatment. Operative procedures to repair ankle instability have shown good clinical results, but the effects of these reconstruction procedures on isolated subtalar instability are not well understood. The goal of this study was to investigate the effect of the Gould modification of the Broström procedure and a new tenodesis reconstruction procedure on ankle and subtalar joint kinematics after simulating a subtalar injury...
November 14, 2016: Foot & Ankle International
https://www.readbyqxmd.com/read/27923196/environmental-preconditioning-rejuvenates-adult-stem-cells-proliferation-and-chondrogenic-potential
#5
REVIEW
Ming Pei
Adult stem cells are a promising cell source for cartilage regeneration. Unfortunately, due to donor age and ex vivo expansion, stem cell senescence becomes a huge hurdle for these cells to be used clinically. Increasing evidence indicates that environmental preconditioning is a powerful approach in promoting stem cells' ability to resist a harsh environment post-engraftment, such as hypoxia and inflammation. However, few reports organize and evaluate the literature regarding the rejuvenation effect of environmental preconditioning on stem cell proliferation and chondrogenic differentiation capacity, which are important variables for stem cell based tissue regeneration...
November 25, 2016: Biomaterials
https://www.readbyqxmd.com/read/27923194/gender-negative-life-events-and-coping-on-different-stages-of-depression-severity-a-cross-sectional-study-among-chinese-university-students
#6
Xiao-Jun Sun, Geng-Feng Niu, Zhi-Qi You, Zong-Kui Zhou, Yun Tang
BACKGROUND: The effects of gender, negative life events, and coping on depression have been well-documented. But depression is a heterogeneous syndrome of which the severity ranged from mild depression to major depression. This study aimed to investigate the specific effects of gender, negative life events, and coping on different stages of depression severity. METHOD: A total of 5989 students (aged 16-25 years, M=20.85, SD=0.58), recruited from six universities in the central region of China using the stratified cluster sampling method, completed Life Events Questionnaire, Coping Response Inventory, and Beck Depression Inventory-Ⅱ...
November 19, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27923181/combined-oral-contraceptive-use-is-associated-with-both-improvement-and-worsening-of-mood-in-the-different-phases-of-the-treatment-cycle-a-double-blind-placebo-controlled-randomized-trial
#7
Cecilia Lundin, Kristina Gemzell Danielsson, Marie Bixo, Lena Moby, Hanna Bengtsdotter, Izabella Jawad, Lena Marions, Jan Brynhildsen, Agota Malmborg, Ingela Lindh, Inger Sundström Poromaa
OBJECTIVE: Ever since the introduction of combined oral contraception (COC), one of the major reasons for discontinuing the pill use has been mood-related side effects. Moreover, women who discontinue the pill turn to less effective methods whereby the probability of an unintended conception increases. Approximately 4-10% of COC users complain of depressed mood, irritability or increased anxiety, but drug-related causality has been difficult to prove. Given the lack of randomized controlled trials in this area, we aimed to prospectively estimate the severity of adverse mood in COC users that would be as representative of general users as possible...
November 29, 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/27923165/outpatient-versus-inpatient-cervix-priming-with-foley-catheter-a-randomized-trial
#8
Catarina Policiano, Mariana Pimenta, Diana Martins, Nuno Clode
OBJECTIVE: To compare clinical efficacy between outpatient and inpatient cervix priming with Foley catheter. STUDY DESIGN: We conducted a randomized trial including term pregnancies with a single fetus in cephalic presentation, Bishop score<6, gestational age>41 weeks or medical indication for induction of labor. Patients were randomized to outpatient (n=65) or inpatient (n=65) priming with Foley catheter. Primary outcome was Bishop score change between outpatient and inpatient groups...
November 27, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27923112/the-double-mandibular-osteotomy-for-vascular-and-tumor-surgery-of-the-parapharyngeal-space
#9
Thomas Schlieve, Eric R Carlson, Michael Freeman, Ryan Buckley, Josh Arnold
PURPOSE: The purposes of this study are to describe our experience using a double mandibular osteotomy for access to the parapharyngeal space in vascular and tumor surgery and to report on the outcomes and complications of this procedure. PATIENTS AND METHODS: We designed and implemented a case series to review the medical records of all patients treated with a double mandibular osteotomy for parapharyngeal space access from 1994 to 2016. Patient demographic characteristics, indications for the procedure, outcomes, and complications were recorded...
November 15, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27923099/cesarean-birth-is-not-associated-with-early-childhood-body-mass-index
#10
L G Smithers, B W Mol, L Jamieson, J W Lynch
Cesarean birth leads to a markedly different microbiome compared to vaginal birth, and the microbiome has been implicated in childhood obesity. Among mothers who had a previous cesarean, we compared anthropometry of 3- to 6-year-old children who were subsequently born by cesarean section versus vaginal birth. This large population-based study involved linking de-identified administrative perinatal and anthropometric data. Children's weight and height were collected at community-based clinics and converted to age- and sex-adjusted z-scores of height-for-age (HFAz), weight-for-age (WFAz) and BMI-for-age (BMIz)...
December 6, 2016: Pediatric Obesity
https://www.readbyqxmd.com/read/27923091/association-between-learning-environment-interventions-and-medical-student-well-being-a-systematic-review
#11
Lauren T Wasson, Amberle Cusmano, Laura Meli, Irene Louh, Louise Falzon, Meghan Hampsey, Geoffrey Young, Jonathan Shaffer, Karina W Davidson
Importance: Concerns exist about the current quality of undergraduate medical education and its effect on students' well-being. Objective: To identify best practices for undergraduate medical education learning environment interventions that are associated with improved emotional well-being of students. Data Sources: Learning environment interventions were identified by searching the biomedical electronic databases Ovid MEDLINE, EMBASE, the Cochrane Library, and ERIC from database inception dates to October 2016...
December 6, 2016: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27923088/prevalence-of-depression-depressive-symptoms-and-suicidal-ideation-among-medical-students-a-systematic-review-and-meta-analysis
#12
Lisa S Rotenstein, Marco A Ramos, Matthew Torre, J Bradley Segal, Michael J Peluso, Constance Guille, Srijan Sen, Douglas A Mata
Importance: Medical students are at high risk for depression and suicidal ideation. However, the prevalence estimates of these disorders vary between studies. Objective: To estimate the prevalence of depression, depressive symptoms, and suicidal ideation in medical students. Data Sources and Study Selection: Systematic search of EMBASE, ERIC, MEDLINE, psycARTICLES, and psycINFO without language restriction for studies on the prevalence of depression, depressive symptoms, or suicidal ideation in medical students published before September 17, 2016...
December 6, 2016: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27923066/somatic-genomics-and-clinical-features-of-lung-adenocarcinoma-a-retrospective-study
#13
Jianxin Shi, Xing Hua, Bin Zhu, Sarangan Ravichandran, Mingyi Wang, Cu Nguyen, Seth A Brodie, Alessandro Palleschi, Marco Alloisio, Gianluca Pariscenti, Kristine Jones, Weiyin Zhou, Aaron J Bouk, Joseph Boland, Belynda Hicks, Adam Risch, Hunter Bennett, Brian T Luke, Lei Song, Jubao Duan, Pengyuan Liu, Takashi Kohno, Qingrong Chen, Daoud Meerzaman, Crystal Marconett, Ite Laird-Offringa, Ian Mills, Neil E Caporaso, Mitchell H Gail, Angela C Pesatori, Dario Consonni, Pier Alberto Bertazzi, Stephen J Chanock, Maria Teresa Landi
BACKGROUND: Lung adenocarcinoma (LUAD) is the most common histologic subtype of lung cancer and has a high risk of distant metastasis at every disease stage. We aimed to characterize the genomic landscape of LUAD and identify mutation signatures associated with tumor progression. METHODS AND FINDINGS: We performed an integrative genomic analysis, incorporating whole exome sequencing (WES), determination of DNA copy number and DNA methylation, and transcriptome sequencing for 101 LUAD samples from the Environment And Genetics in Lung cancer Etiology (EAGLE) study...
December 2016: PLoS Medicine
https://www.readbyqxmd.com/read/27923051/electrophysiological-characteristics-of-human-ipsc-derived-cardiomyocytes-for-the-assessment-of-drug-induced-proarrhythmic-potential
#14
Wataru Yamamoto, Keiichi Asakura, Hiroyuki Ando, Tomohiko Taniguchi, Atsuko Ojima, Takaaki Uda, Tomoharu Osada, Seiji Hayashi, Chieko Kasai, Norimasa Miyamoto, Hiroyuki Tashibu, Takashi Yoshinaga, Daiju Yamazaki, Atsushi Sugiyama, Yasunari Kanda, Kohei Sawada, Yuko Sekino
The aims of this study were to (1) characterize basic electrophysiological elements of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) that correspond to clinical properties such as QT-RR relationship, (2) determine the applicability of QT correction and analysis methods, and (3) determine if and how these in-vitro parameters could be used in risk assessment for adverse drug-induced effects such as Torsades de pointes (TdP). Field potential recordings were obtained from commercially available hiPSC-CMs using multi-electrode array (MEA) platform with and without ion channel antagonists in the recording solution...
2016: PloS One
https://www.readbyqxmd.com/read/27923011/feasibility-and-acceptability-of-health-communication-interventions-within-a-combination-intervention-strategy-for-improving-linkage-and-retention-in-hiv-care-in-mozambique
#15
Roberta Sutton, Maria Lahuerta, Fatima Abacassamo, Laurence Ahoua, Maria Tomo, Matthew R Lamb, Batya Elul
BACKGROUND: Challenges to ensuring timely linkage to and retention in HIV care are well documented. Combination intervention strategies can be effective in improving the HIV care continuum. Data on feasibility and acceptability of intervention types within intervention packages are limited. METHODS: The Engage4Health study assessed the effectiveness of a combination intervention strategy to increase linkage and retention among adults newly diagnosed with HIV in Mozambique...
January 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27923010/effective-interpersonal-health-communication-for-linkage-to-care-after-hiv-diagnosis-in-south-africa
#16
Tonderai Mabuto, Salome Charalambous, Christopher J Hoffmann
BACKGROUND: Early in the global response to HIV, health communication was focused toward HIV prevention. More recently, the role of health communication along the entire HIV care continuum has been highlighted. We sought to describe how a strategy of interpersonal communication allows for precision health communication to influence behavior regarding care engagement. METHODS: We analyzed 1 to 5 transcripts from clients participating in longitudinal counseling sessions from a communication strategy arm of a randomized trial to accelerate entry into care in South Africa...
January 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27922983/current-construct-options-for-revision-of-large-acetabular-defects-a-systematic-review
#17
Marieke Baauw, Miranda L van Hooff, Maarten Spruit
BACKGROUND: Many treatment options are available for the revision of large acetabular defects. Debate continues as to which technique is most effective. METHODS: A systematic review was performed according to the Meta-analysis of Observational Studies in Epidemiology (MOOSE) guidelines to evaluate the effectiveness of interventions for large acetabular defects. Quality assessment was performed next with use of 8 items of the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist for reports of observational studies...
November 8, 2016: JBJS Reviews
https://www.readbyqxmd.com/read/27922969/orbital-morphometry-a-computed-tomography-analysis
#18
Jaswinder Singh, Roselinda Ab Rahman, Zainul Ahmad Rajion, Johari Abdullah, Irfan Mohamad
INTRODUCTION: The human orbit is a complex anatomic region, which plays predominant role in the evaluation of craniofacial complex. A thorough understanding of the relationship of the distance from orbital rim to the important vital structures of the orbital apex is required for the surgeon to perform safe and effective surgery. OBJECTIVES: To evaluate and compare the depth and distances from various points of the orbital rim to the fissures and foramina of the orbital apex between genders in the local population...
December 5, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27922950/a-prospective-randomized-comparative-trial-of-targeted-steroid-injection-via-epidural-catheter-versus-standard-c7-t1-interlaminar-approach-for-the-treatment-of-unilateral-cervical-radicular-pain
#19
Zachary L McCormick, Ariana Nelson, Meghan Bhave, Mikhail Zhukalin, Mark Kendall, Robert J McCarthy, Dost Khan, Geeta Nagpal, David R Walega
BACKGROUND AND OBJECTIVES: No study has compared cervical interlaminar epidural steroid injection (CIESI) with epidural catheter advancement to the side and level of pathology versus standard C7-T1 CIESI. This study investigated whether cervical radicular pain is more effectively treated by CIESI with a targeted epidural catheter versus a standard C7-T1 approach. METHODS: Prospective, randomized, single-blinded trial. PRIMARY OUTCOME: Numerical Rating Scale (NRS) pain at 1 month...
December 5, 2016: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/27922948/fluoroscopic-guidance-increases-the-incidence-of-thoracic-epidural-catheter-placement-within-the-epidural-space-a-randomized-trial
#20
Michelle C Parra, Kristin Washburn, Jeremiah R Brown, Michael L Beach, Mark P Yeager, Patricia Barr, Kathy Bonham, Kathryn Lamb, Randy W Loftus
BACKGROUND AND OBJECTIVES: Thoracic epidural analgesia can reduce postoperative pain and cardiopulmonary morbidity, but it is associated with a high rate of clinical failure. Up to 50% of clinical failure is thought to be related to technical insertion. In this study, patients undergoing thoracic surgery were randomized to one of two catheter insertion techniques: fluoroscopically guided or conventional loss of resistance with saline/air. Our primary aim was to examine whether fluoroscopic guidance could increase the incidence of correct catheter placement and improve postoperative analgesia...
December 5, 2016: Regional Anesthesia and Pain Medicine
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