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Arterial wave pulse in elderly

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https://www.readbyqxmd.com/read/27754073/os-18-05-sarcopenia-is-independently-associated-with-arterial-stiffness-in-patients-with-type-2-diabetes
#1
Yuki Imaizumi, Kazuo Eguchi, Toshiki Kaihara, Kumiko Urano, Rieko Shinagawa, Minoru Araki, Koji Inoue, Koichiro Hokao, Yuka Tsujita, Takuya Furusawa, Ryuichiro Kaku, Kazuomi Kario
OBJECTIVE: We tested the hypothesis that sarcopenia, an age-related loss of skeletal muscle mass and function, is associated with arterial stiffness in patients with diabetes (DM). DESIGN AND METHOD: We studied 65 hypertensives in the Real BP study, an observational study of home BP telemonitoring system. As parameters of sarcopenia, we used locomotive syndrome scale, circumference of the wrist, lower leg, and thigh (10 cm above the patella), grip strength, and 6 minute-walk test...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27753881/ish-ada-02-comparison-of-pulse-wave-velocity-and-pulse-pressure-amplification-in-the-association-with-target-organ-damages-in-the-community-based-elderly-the-northern-shanghai-study
#2
Bin Bai, Jin Xiong, Yuyan Lv, Shikai Yu, Jiadela Teliewubai, Chen Chi, Yiwu Zhou, Kai Wang, Le Wang, Yi Zhang, Yawei Xu
OBJECTIVE: To investigate the discrepancy between PWV and PPA in association with hypertensive TODs in the elderly population. DESIGN AND METHOD: From June 2014 to August 2015, a total of 1599 community-based elderly subjects (age > 65 years old) located in the northern Shanghai were recruited. The carotid-femoral pulse wave velocity (cfPWV), peripheral blood pressure (BP), central BP and other TODs indicators including the ratio of the early ventricular filling velocity (E) to the peak velocity of tissue Doppler velocity of septal mitral annulus (E/Ea), left ventricular mass index (LVMI), carotid intima-medium thickness (IMT), estimated glomerular filtration rate (eGFR), urinary albumin-creatinine rate (ACR) were assessed on each participant...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27753801/ssa-01-4-the-characteristics-of-arterial-stiffness-in-east-asia
#3
Chen-Huan Chen
Aging causes progressive changes in the structure and function of the large arteries that adversely impact the heart and vital organs. Vascular aging is a major independent risk factor for the development of cardiovascular diseases and events. Arterial stiffening is the dominant hemodynamic manifestation of vascular aging and a major independent predictor for incident hypertension. Arterial stiffening is therefore responsible for the very high residual lifetime risk for hypertension for middle-aged and elderly individuals...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27643174/ish-ada-02-comparison-of-pulse-wave-velocity-and-pulse-pressure-amplification-in-the-association-with-target-organ-damages-in-the-community-based-elderly-the-northern-shanghai-study
#4
Bin Bai, Jin Xiong, Yuyan Lv, Shikai Yu, Jiadela Teliewubai, Chen Chi, Yiwu Zhou, Kai Wang, Le Wang, Yi Zhang, Yawei Xu
OBJECTIVE: To investigate the discrepancy between PWV and PPA in association with hypertensive TODs in the elderly population. DESIGN AND METHOD: From June 2014 to August 2015, a total of 1599 community-based elderly subjects (age > 65 years old) located in the northern Shanghai were recruited. The carotid-femoral pulse wave velocity (cfPWV), peripheral blood pressure (BP), central BP and other TODs indicators including the ratio of the early ventricular filling velocity (E) to the peak velocity of tissue Doppler velocity of septal mitral annulus (E/Ea), left ventricular mass index (LVMI), carotid intima-medium thickness (IMT), estimated glomerular filtration rate (eGFR), urinary albumin-creatinine rate (ACR) were assessed on each participant...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27642994/os-18-05-sarcopenia-is-independently-associated-with-arterial-stiffness-in-patients-with-type-2-diabetes
#5
Yuki Imaizumi, Kazuo Eguchi, Toshiki Kaihara, Kumiko Urano, Rieko Shinagawa, Minoru Araki, Koji Inoue, Koichiro Hokao, Yuka Tsujita, Takuya Furusawa, Ryuichiro Kaku, Kazuomi Kario
OBJECTIVE: We tested the hypothesis that sarcopenia, an age-related loss of skeletal muscle mass and function, is associated with arterial stiffness in patients with diabetes (DM). DESIGN AND METHOD: We studied 65 hypertensives in the Real BP study, an observational study of home BP telemonitoring system. As parameters of sarcopenia, we used locomotive syndrome scale, circumference of the wrist, lower leg, and thigh (10 cm above the patella), grip strength, and 6 minute-walk test...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27642870/ssa-01-4-the-characteristics-of-arterial-stiffness-in-east-asia
#6
Chen-Huan Chen
Aging causes progressive changes in the structure and function of the large arteries that adversely impact the heart and vital organs. Vascular aging is a major independent risk factor for the development of cardiovascular diseases and events. Arterial stiffening is the dominant hemodynamic manifestation of vascular aging and a major independent predictor for incident hypertension. Arterial stiffening is therefore responsible for the very high residual lifetime risk for hypertension for middle-aged and elderly individuals...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27624389/a-simple-adaptive-transfer-function-for-deriving-the-central-blood-pressure-waveform-from-a-radial-blood-pressure-waveform
#7
Mingwu Gao, William C Rose, Barry Fetics, David A Kass, Chen-Huan Chen, Ramakrishna Mukkamala
Generalized transfer functions (GTFs) are available to compute the more relevant central blood pressure (BP) waveform from a more easily measured radial BP waveform. However, GTFs are population averages and therefore may not adapt to variations in pulse pressure (PP) amplification (ratio of radial to central PP). A simple adaptive transfer function (ATF) was developed. First, the transfer function is defined in terms of the wave travel time and reflection coefficient parameters of an arterial model. Then, the parameters are estimated from the radial BP waveform by exploiting the observation that central BP waveforms exhibit exponential diastolic decays...
September 14, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27190377/aortic-stiffness-and-change-in-glomerular-filtration-rate-and-albuminuria-in-older-people
#8
Naya Huang, Meredith C Foster, Gary F Mitchell, Margret B Andresdottir, Gudny Eiriksdottir, Hrefna Gudmundsdottir, Tamara B Harris, Lenore J Launer, Runolfur Palsson, Vilmundur Gudnason, Andrew S Levey, Lesley A Inker
BACKGROUND: Aortic stiffness increases with age and increases pulsatile stress in the microcirculation. Abnormalities in kidney microvascular structure and function may contribute to development or progression of chronic kidney disease in older people. METHODS: We performed a longitudinal analysis of 629 community-dwelling elderly Icelandic adults from the Age, Gene/Environment Susceptibility-Reykjavik Study with two visits over a mean follow-up of 5.3 years. We evaluated the associations of carotid-femoral pulse wave velocity (CFPWV), carotid pulse pressure (CPP) and augmentation index (AI), with the change in estimated glomerular filtration rate (eGFR) and urine albumin-to-creatinine ratio (UACR) assessed as annual change and dichotomized as large changes...
March 28, 2016: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/27159403/the-association-between-oxidative-stress-activator-protein-1-inflammatory-total-antioxidant-status-and-artery-stiffness-and-the-efficacy-of-olmesartan-in-elderly-patients-with-mild-to-moderate-essential-hypertension
#9
Qunwei Liu, Limin Han, Qiufan Du, Ming Zhang, Shenghua Zhou, Xiangqian Shen
This study investigated the change of oxidative stress, activator protein-1 (AP-1), inflammatory, total antioxidant status (TAS) and artery stiffness, and explored the relationship between these characteristics and the efficacy of olmesartan intervention in elderly patients with mild-to-moderate essential hypertension (EH). In total, 386 elderly patients with EH and 353 normotensive controls were recruited. All study subjects had oxidative stress markers, AP-1, inflammatory factors, TAS and brancial-ankle artery pulse wave velocity (ba-PWV) measured...
2016: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/27151211/long-sleep-duration-a-nonconventional-indicator-of-arterial-stiffness-in-japanese-at-high-risk-of-cardiovascular-disease-the-j-hop-study
#10
Satoshi Niijima, Michiaki Nagai, Satoshi Hoshide, Mami Takahashi, Masahisa Shimpo, Kazuomi Kario
Long and short sleep durations were reported as independently associated with hypertension, aortic stiffness, and cardiovascular disease. High-sensitivity C-reactive protein (hs-CRP) was shown to be associated with increased aortic stiffness. Here, we investigated the relationship between self-reported sleep duration and pulse wave velocity (PWV) in the elderly at high risk of cardiovascular disease. We also investigated whether hs-CRP moderates this relationship. Among 4310 patients with ≥1 cardiovascular risks recruited for the Japan Morning Surge-Home Blood Pressure Study, a questionnaire including items on daily sleep duration was completed...
May 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/27136311/arterial-stiffness-and-medial-temporal-lobe-atrophy-in-elders-with-memory-disorders
#11
Matthieu Lilamand, Jean-Sébastien Vidal, Matthieu Plichart, Laura W De Jong, Emmanuelle Duron, Olivier Hanon
OBJECTIVES: Hypertension is a risk factor for cognitive impairment and dementia. Arterial stiffness could be involved in the mechanisms of vascular cognitive impairment and in Alzheimer's disease. We examined the association between arterial stiffness, assessed by carotid-femoral pulse wave velocity (PWV), and medial temporal lobe (MTL) atrophy, a biomarker of Alzheimer's disease. METHODS: Elderly community-dwelling study participants (n = 149) with memory complaints were diagnosed with Alzheimer's disease (n = 62) or mild cognitive impairment (n = 87) at a memory clinic...
July 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27040097/vascular-aging-lessons-from-pediatric-hypertension
#12
REVIEW
Mieczyslaw Litwin, Janusz Feber, Marcel Ruzicka
Hypertension (HTN) in children is associated with early vascular aging (EVA) and underlying immunologic-metabolic abnormalities and accelerated biological maturation. Morphologic and functional vascular changes underlying EVA and HTN in children resemble those seen in the elderly including but not limited to an increase in intima-media thickness (IMT) and arterial stiffness and endothelial dysfunction. Although progeria syndrome leading to EVA and the development of clinically manifested cardiovascular (CV) disease in the second decade of life is a rare hereditary disorder, primary HTN, which is also associated with EVA, is much more common (reported in up to 10% in adolescents)...
May 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/26892585/influence-of-thoracic-aortic-inflammation-and-calcifications-on-arterial-stiffness-and-cardiac-function-in-older-subjects
#13
L Joly, D Mandry, A Verger, C Labat, G Watfa, V Roux, G Karcher, P-Y Marie, A Benetos
BACKGROUND: Vascular aging is accompanied by gradual remodeling affecting both arterial and cardiac structure and mechanical properties. Hypertension is suggested to exert pro-inflammatory actions enhancing arterial stiffness. OBJECTIVE: To determine the influence of thoracic aortic inflammation and calcifications on arterial stiffness and cardiac function in hypertensive and normotensive older subjects. DESIGN: A prospective study. SETTING: An acute geriatrics ward of the University Hospital of Nancy in France...
March 2016: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/26823470/aging-alters-the-dampening-of-pulsatile-blood-flow-in-cerebral-arteries
#14
Laleh Zarrinkoob, Khalid Ambarki, Anders Wåhlin, Richard Birgander, Bo Carlberg, Anders Eklund, Jan Malm
Excessive pulsatile flow caused by aortic stiffness is thought to be a contributing factor for several cerebrovascular diseases. The main purpose of this study was to describe the dampening of the pulsatile flow from the proximal to the distal cerebral arteries, the effect of aging and sex, and its correlation to aortic stiffness. Forty-five healthy elderly (mean age 71 years) and 49 healthy young (mean age 25 years) were included. Phase-contrast magnetic resonance imaging was used for measuring blood flow pulsatility index and dampening factor (proximal artery pulsatility index/distal artery pulsatility index) in 21 cerebral and extra-cerebral arteries...
September 2016: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/26781275/pulse-waves-in-the-lower-extremities-as-a-diagnostic-tool-of-peripheral-arterial-disease-and-predictor-of-mortality-in-elderly-chinese
#15
Chang-Sheng Sheng, Yan Li, Qi-Fang Huang, Yuan-Yuan Kang, Fei-Ka Li, Ji-Guang Wang
Patients with peripheral arterial disease may have elongated upstroke time in pulse waves in the lower extremities. We investigated upstroke time as a diagnostic tool of peripheral arterial disease and predictor of mortality in an elderly (≥60 years) Chinese population. We recorded pulse waves at the left and right ankles by pneumoplethysmography and calculated the percentage of upstroke time per cardiac cycle. Diagnostic accuracy was compared with the conventional ankle-brachial index method (n=4055) and computed tomographic angiography (34 lower extremities in 17 subjects)...
March 2016: Hypertension
https://www.readbyqxmd.com/read/26599357/tcd-profiling-using-average-a-new-technique-to-evaluate-transcranial-doppler-ultrasound-flow-spectra-of-subjects-with-cerebral-small-vessel-disease
#16
Anna Lena Fisse, Johannes Pueschel, Michael Deppe, E Bernd Ringelstein, Martin A Ritter
BACKGROUND: There is an unmet need for screening methods to detect and quantify cerebral small vessel disease (SVD). Transcranial Doppler ultrasound (TCD) flow spectra of the larger intracranial arteries probably contain relevant information about the microcirculation. However, it has not yet been possible to exploit this information as a valuable biomarker. METHODS: We developed a technique to generate normalized and averaged flow spectra during middle cerebral artery Doppler ultrasound examinations...
2016: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/26597152/relation-of-central-arterial-stiffness-to-incident-heart-failure-in-the-community
#17
Connie W Tsao, Asya Lyass, Martin G Larson, Daniel Levy, Naomi M Hamburg, Joseph A Vita, Emelia J Benjamin, Gary F Mitchell, Ramachandran S Vasan
BACKGROUND: Arterial stiffness, pressure pulsatility, and wave reflection are associated with cardiovascular disease. Left ventricular function is coupled to proximal aortic properties, but the association of central aortic stiffness and hemodynamics with incident clinical heart failure (HF) is not well described. METHODS AND RESULTS: Framingham Study participants without clinical HF (n=2539, mean age 64 years, 56% women) underwent applanation tonometry to measure carotid-femoral pulse wave velocity (CFPWV), central pulse pressure, forward wave amplitude, and augmentation index...
November 23, 2015: Journal of the American Heart Association
https://www.readbyqxmd.com/read/26587457/arterial-stiffening-and-clinical-outcomes-in-dialysis-patients
#18
REVIEW
Akihiko Kato
Cardiovascular disease (CVD) is an important cause of morbidity and mortality in dialysis patients. Brachial-ankle pulse wave velocity (baPWV) is more efficient to handily assess arteriosclerosis than aortic PWV. The cardio-ankle vascular index (CAVI) is also a novel blood pressure-independent arterial stiffness parameter. In dialysis patients, both baPWV and CAVI are increased compared to general subjects. Several studies have demonstrated that increased baPWV is associated with carotid atherosclerosis and diastolic left ventricular dysfunction in hemodialysis (HD) patients...
September 2015: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/26571979/evaluation-of-arterial-stiffness-in-elderly-with-prehypertension
#19
Patil Satish Gurunathrao, Aithala Manjunatha, Das Kusal Kanti
Arterial stiffness is an independent marker of cardiovascular (CV) risk that increases with age. Hypertension is known to augment the age-related arterial stiffness. The influence of prehypertension on arterial stiffness in elderly is least studied. The present study was aimed to assess the age-associated arterial stiffness in the elderly subjects with prehypertension. A cross sectional study was conducted on elderly subjects aged 60-80 years with prehypertension (n=25) and age-matched normotensives (n=20)...
January 2015: Indian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/26386864/factors-influencing-the-relationship-between-atrial-fibrillation-and-artery-stiffness-in-elderly-chinese-patients-with-hypertension
#20
Di Shi, Qingtao Meng, Xiaoyan Zhou, Longxin Li, Kai Liu, Sen He, Si Wang, Xiaoping Chen
BACKGROUND AND AIMS: Atrial fibrillation (AF) is often accompanied by vascular dysfunction in the elderly. The influencing factors in the development of AF are unclear. The aim of this study was to identify links between arterial stiffness and AF to provide new directions for the prevention of AF. METHODS: We recruited 132 patients with both hypertension and AF (78 with paroxysmal AF and 84 with persistent AF) and 136 hypertensive patients. Questionnaires, physical examinations, and laboratory tests were conducted using standard protocols...
August 2016: Aging Clinical and Experimental Research
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