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Arterial wave pulse in elderly

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https://www.readbyqxmd.com/read/29663586/adiposity-body-composition-and-ventricular-arterial-stiffness-in-the-elderly-the-atherosclerosis-risk-in-communities-study
#1
Miguel M Fernandes-Silva, Amil M Shah, Brian Claggett, Susan Cheng, Hirofumi Tanaka, Odilson M Silvestre, Wilson Nadruz, Barry A Borlaug, Scott D Solomon
AIM: Weight gain appears to accelerate age-related ventricular-arterial stiffening, which has been implicated in the development of heart failure (HF), but it is unclear whether body fat accumulation underpins this association. We evaluated the relationship of adiposity, using measures of body composition, with ventricular-arterial stiffness among the elderly in the community. METHODS AND RESULTS: Adiposity was accessed through body mass index (BMI), waist circumference, and body fat percentage...
April 16, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29662306/short-term-vascular-hemodynamic-responses-to-isometric-exercise-in-young-adults-and-in-the-elderly
#2
Renee Hartog, Davide Bolignano, Eric Sijbrands, Giacomo Pucci, Francesco Mattace-Raso
Background: Vascular aging is known to induce progressive stiffening of the large elastic arteries, altering vascular hemodynamics under both rest and stress conditions. In this study, we aimed to investigate changes in vascular hemodynamics in response to isometric handgrip exercise across ages. Participants and methods: We included 62 participants, who were divided into three age categories: 20-40 (n=22), 41-60 (n=20), and 61-80 (n=20) years. Vascular hemodynamics were measured using the Mobil-o-Graph® based on the pulsatile pressure changes in the brachial artery...
2018: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29551893/association-of-asymptomatic-target-organ-damage-with-secreted-frizzled-related-protein-5-in-the-elderly-the-northern-shanghai-study
#3
Jiadela Teliewubai, Bin Bai, Yiwu Zhou, Yuyan Lu, Shikai Yu, Chen Chi, Jue Li, Jacques Blacher, Yawei Xu, Yi Zhang
Objective: Secreted frizzled related protein 5 (SFRP5) is a novel anti-inflammatory adipokine that is implicated in metabolic and cardiovascular disease (CVD). However, little is known about the relevance of SFRP5 with asymptomatic hypertensive target organ damages (TODs). We aimed to investigate the association between SFRP5 and TOD in a large population. Clinical trial registration: NCT02368938. Methods: A total of 1,745 community-dwelling elderly subjects aged over 65 years from northern Shanghai were recruited in the study...
2018: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29535455/comparison-of-pulse-wave-velocity-and-pulse-pressure-amplification-in-association-with-target-organ-damage-in-community-dwelling-elderly-the-northern-shanghai-study
#4
Bin Bai, Jiadela Teliewubai, Yuyan Lu, Shikai Yu, Jing Xiong, Chen Chi, Yiwu Zhou, Hongwei Ji, Ximin Fan, Jacques Blacher, Jue Li, Yi Zhang, Yawei Xu
This study aimed to investigate the discrepancy between pulse wave velocity (PWV) and pulse pressure amplification (PPA) in association with hypertensive target organ damage (TOD) in the elderly. From June 2014 to August 2015, 1599 participants aged >65 years old from communities located in northern Shanghai were recruited. Carotid-femoral pulse wave velocity (cfPWV), peripheral blood pressure (BP), central BP and other TOD indicators, including the ratio of the early ventricular filling velocity (E) to the peak velocity of the tissue Doppler velocity of septal mitral annulus (E/Ea), left ventricular mass index (LVMI), carotid intima-medium thickness (CIMT), estimated glomerular filtration rate (eGFR), and urinary albumin-creatinine ratio (ACR), were determined for each participant...
March 13, 2018: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/29530075/prospective-associations-between-pulse-pressure-and-cognitive-performance-in-chinese-middle-aged-and-older-population-across-a-5-year-study-period
#5
Tingting Sha, Wenwei Cheng, Yan Yan
BACKGROUND: Substantial evidence indicates that the relationship between blood pressure (BP) measures and cognitive functioning is inconsistent, complex, and age-related. Pulse pressure (PP), which can not only reflect arterial stiffness and but also represent the chronic effects of hypertension other than BP itself, has been considered as a better predictor of cognitive impairment. However, evidence on the association of cognitive function with PP has not been investigated extensively...
March 12, 2018: Alzheimer's Research & Therapy
https://www.readbyqxmd.com/read/29525195/advanced-age-attenuates-left-ventricular-filling-efficiency-quantified-using-vortex-formation-time-a-study-of-octogenarians-with-normal-left-ventricular-systolic-function-undergoing-coronary-artery-surgery
#6
Paul S Pagel, Lonnie Dye, Brent T Boettcher, Julie K Freed
OBJECTIVE: Blood flow across the mitral valve during early left ventricular (LV) filling produces a 3-dimensional rotational fluid body, known as a vortex ring, that enhances LV filling efficiency. Diastolic dysfunction is common in elderly patients, but the influence of advanced age on vortex formation is unknown. The authors tested the hypothesis that advanced age is associated with a reduction in LV filling efficiency quantified using vortex formation time (VFT) in octogenarians undergoing coronary artery bypass graft (CABG) surgery...
March 7, 2018: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29449705/comparison-between-l-type-and-n-l-type-calcium-channel-blockers-in-the-regulation-of-home-blood-pressure-variability-in-elderly-hypertensive-patients
#7
Satoko Nozato, Koichi Yamamoto, Yoichi Nozato, Masao Takeda, Kazuhiro Hongyo, Miyuki Takeya, Hiroshi Akasaka, Yoichi Takami, Yasushi Takeya, Ken Sugimoto, Norihisa Ito, Hiromi Rakugi
Recent studies suggest that L-type calcium channel blockers (CCBs) contribute to reducing blood pressure (BP) variability. We investigated whether inhibition of the N-type calcium channel has an additional effect on BP variability by comparing the effect of L-type and L/N-type CCBs on home BP variability in elderly hypertensive patients. Twenty-six hypertensive patients (≥65 years) were subjected to repeated changes with the administration of amlodipine (L-type CCB) and cilnidipine (L/N-type CCB) every 2 months...
February 15, 2018: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/29396106/the-prevalence-of-central-hypertension-defined-by-a-central-blood-pressure-type-i-device-and-its-association-with-target-organ-damage-in-the-community-dwelling-elderly-chinese-the-northern-shanghai-study
#8
Shikai Yu, Jing Xiong, Yuyan Lu, Chen Chi, Jiadela Teliewubai, Bin Bai, Hongwei Ji, Yiwu Zhou, Ximin Fan, Jacques Blacher, Jue Li, Yi Zhang, Yawei Xu
We aimed to investigate the prevalence of central hypertension and its association with target organ damage (TOD). 1983 community-dwelling elderly Chinese people were recruited for this analysis. Brachial and central blood pressure (BP) were measured by an oscillometric device and SphygmoCor (type I device), respectively. Brachial hypertension was defined by brachial systolic BP/diastolic BP ≥140/90 mmHg or using antihypertensive medications. Central hypertension was defined by central systolic BP/diastolic BP ≥130/90 mmHg or using antihypertensive medications...
January 3, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29395643/ideal-cardiovascular-health-and-arterial-stiffness-in-spanish-adults-the-evident-study
#9
Antonio García-Hermoso, Vicente Martínez-Vizcaíno, Manuel Ángel Gomez-Marcos, Iván Cavero-Redondo, José Ignacio Recio-Rodriguez, Luis García-Ortiz
BACKGROUND: Studies concerning ideal cardiovascular (CV) health and its relationship with arterial stiffness are lacking. This study examined the association between arterial stiffness with ideal CV health as defined by the American Heart Association, across age groups and gender. METHODS: The cross-sectional study included 1365 adults. Ideal CV health was defined as meeting ideal levels of the following components: 4 behaviors (smoking, body mass index, physical activity, and Mediterranean diet adherence) and 3 factors (total cholesterol, blood pressure, and glycated hemoglobin)...
January 24, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29370669/the-role-of-habitual-physical-activity-on-arterial-stiffness-in-elderly-individuals-a-systematic-review-and-meta-analysis
#10
Wonil Park, Hun-Young Park, Kiwon Lim, Jonghoon Park
PURPOSE: Physical inactivity behavior at middle age or older is a major risk factor for cardiovascular disease. However, the effects of levels of habitual physical activity on arterial stiffness in elderly population remain unclear currently. Therefore, the purpose of this study was to demonstrate whether the effects of habitual physical activity could attenuate arterial stiffness in elderly individuals via a meta-analysis. METHODS: We searched the Medline and Embase databases from January 1997 through November 2017, using the medical subject headings "older population", "physical activity" (e...
December 31, 2017: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/29368039/assessment-of-subtle-changes-in-diabetes-associated-arteriosclerosis-using-photoplethysmographic-pulse-wave-from-index-finger
#11
Po-Chun Hsu, Hsien-Tsai Wu, Cheuk-Kwan Sun
Distortions in macro- and microcirculation are principal contributors to diabetes-associated complications. This study aimed at investigating the validity of applying non-invasive photoplethysmographic (PPG) waveform parameters in detecting diabetes-induced subtitle changes in arterial stiffness. Between July 2009 and October 2010, totally 94 middle-aged and elderly subjects were recruited including 48 without diabetes (Group 1) and 46 with the disease (Group 2). Demographic (i.e., age, gender), anthropometric (body-mass index), biochemical (i...
January 24, 2018: Journal of Medical Systems
https://www.readbyqxmd.com/read/29316158/reduced-stroke-distance-of-the-left-ventricular-outflow-tract-is-independently-associated-with-long-term-mortality-in-patients-hospitalized-due-to-heart-failure
#12
You Zhong, Qays Almodares, JieFu Yang, Fang Wang, Michael Fu, Magnus C Johansson
PURPOSE: Reduced blood circulation is an important feature of heart failure, and Doppler stroke distance of the left ventricular outflow tract is a measure of forward stroke volume. Several echocardiographic parameters have known prognostic implications in heart failure, but the prognostic implications of stroke distance in relation to other parameters are insufficiently known. The aim was therefore to test the hypothesis that stroke distance is associated with five-year all-cause mortality, independently of other echocardiography variables, and that stroke distance has added long-term prognostic value...
January 9, 2018: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/29310327/prevalence-and-clinical-characteristics-of-pseudohypertension-in-elderly-patients-prepared-for-coronary-artery-angiography
#13
Xixi Dai, Haiya Wang, Ningyuan Fang
BACKGROUND: Pseudohypertension (PHT) can cause adverse effects in the elderly owing to administration of antihypertension therapy. The present study aimed to determine the prevalence of PHT in the elderly and associated risk factors to investigate a noninvasive method of detection of PHT. METHODS: We recruited 151 patients (age ≥60 years) who underwent coronary angiography. Demographic and clinical data were collected from the patients. During coronary angiography, intrabrachial arterial pressure and indirect blood pressure were measured...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29177410/relationship-of-acid-base-status-with-arterial-stiffness-in-community-living-elders-the-health-abc-study
#14
Wei Chen, Anne B Newman, Linda F Fried, Dena E Rifkin, Michael G Shlipak, Mark J Sarnak, Ronit Katz, Magdalena Madero, Kalani L Raphael, David A Bushinsky, Joachim H Ix
Background: Animal studies suggest that acidosis protects against arterial calcification, which contributes to arterial stiffness. The goal of this study was to investigate the associations of serum bicarbonate and pH with arterial stiffness in community-living older adults. Methods: We performed cross-sectional analyses among 1698 well-functioning participants 70-79 years of age. Bicarbonate and pH were measured by arterialized venous blood gas at the point of care...
November 21, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29059329/short-term-repeatability-of-noninvasive-aortic-pulse-wave-velocity-assessment-comparison-between-methods-and-devices
#15
Andrea Grillo, Gianfranco Parati, Matteo Rovina, Francesco Moretti, Lucia Salvi, Lan Gao, Corrado Baldi, Giovanni Sorropago, Andrea Faini, Sandrine C Millasseau, Filippo Scalise, Renzo Carretta, Paolo Salvi
BACKGROUND: Aortic pulse wave velocity (PWV) is an indirect index of arterial stiffness and an independent cardiovascular risk factor. Consistency of PWV assessment over time is thus an essential feature for its clinical application. However, studies providing a comparative estimate of the reproducibility of PWV across different noninvasive devices are lacking, especially in the elderly and in individuals at high cardiovascular risk. METHODS: Aimed at filling this gap, short-term repeatability of PWV, estimated with 6 different devices (Complior Analyse, PulsePen-ETT, PulsePen-ET, SphygmoCor Px/Vx, BPLab, and Mobil-O-Graph), was evaluated in 102 high cardiovascular risk patients hospitalized for suspected coronary artery disease (72 males, 65 ± 13 years)...
December 8, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28976207/metabolomic-profile-of-arterial-stiffness-in-aged-adults
#16
Angela S Koh, Fei Gao, Jin Liu, Kevin Timothy Fridianto, Jianhong Ching, Ru San Tan, Jia-Ing Wong, Serene Jm Chua, Shuang Leng, Liang Zhong, Bryan Mh Keng, Fei Qiong Huang, Jian-Min Yuan, Woon-Puay Koh, Jean-Paul Kovalik
BACKGROUND: Increasing arterial stiffness is an important contributor to declining cardiovascular health in ageing. Changes in whole-body fuel metabolism could be related to alterations in arterial stiffness in ageing adults. METHODS: Targeted high-performance liquid and gas chromatography mass spectrometry were used to measure 84 circulating metabolites in a group of community elderly adults ( n = 141, 58% men; mean age = 70.6 ± 11.2 years) without cardiovascular disease...
January 2018: Diabetes & Vascular Disease Research
https://www.readbyqxmd.com/read/28952815/blood-pressure-goal-for-the-elderly-chinese-the-findings-from-the-northern-shanghai-study
#17
Jiadela Teliewubai, Bin Qiu, Yuyan Lu, Bin Bai, Shikai Yu, Yiwu Zhou, Chen Chi, Jing Xiong, Hongwei Ji, Ximin Fan, Jue Li, Jacques Blacher, Yawei Xu, Yi Zhang
BACKGROUND: The Eighth Joint National Committee Panel (JNC8) recommended a novel blood pressure (BP) goal for individuals with hypertension, which was less stringent than the Seventh Joint National Committee (JNC7) guideline and is still under debate. In our study, we aimed at finding a better BP goal for the elderly Chinese. METHODS: About 1599 community-based elderly participants were recruited in the northern Shanghai and were classified by chronic kidney disease or diabetes mellitus to investigate their BP control conditions based on both the JNC7 and JNC8...
September 27, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28870545/arterial-stiffness-and-cognitive-impairment
#18
REVIEW
Xiaoxuan Li, Peiyuan Lyu, Yanyan Ren, Jin An, Yanhong Dong
BACKGROUND: Arterial stiffness is one of the earliest indicators of changes in vascular wall structure and function and may be assessed using various indicators, such as pulse-wave velocity (PWV), the cardio-ankle vascular index (CAVI), the ankle-brachial index (ABI), pulse pressure (PP), the augmentation index (AI), flow-mediated dilation (FMD), carotid intima media thickness (IMT) and arterial stiffness index-β. Arterial stiffness is generally considered an independent predictor of cardiovascular and cerebrovascular diseases...
September 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28870151/progression-of-arterial-stiffness-is-associated-with-changes-in-bone-mineral-markers-in-advanced-ckd
#19
Rathika Krishnasamy, Sven-Jean Tan, Carmel M Hawley, David W Johnson, Tony Stanton, Kevin Lee, David W Mudge, Scott Campbell, Grahame J Elder, Nigel D Toussaint, Nicole M Isbel
BACKGROUND: Arterial stiffness is an independent predictor of all-cause and cardiovascular mortality in patients with chronic kidney disease (CKD). There are limited prospective data however on progression of arterial stiffness in CKD, including evaluating associations with bone mineral markers such as fibroblast growth factor 23 (FGF23) and soluble α-klotho (sKl). METHODS: In this prospective, single-center, observational study, arterial stiffness [measured by pulse wave velocity (PWV)] and hormones influencing mineral homeostasis, including serum FGF23 and sKl, were compared between non-dialysis CKD stages 4/5 and healthy controls at baseline and 12 months (12 m)...
September 4, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28822516/comparison-of-yoga-and-walking-exercise-on-cardiac-time-intervals-as-a-measure-of-cardiac-function-in-elderly-with-increased-pulse-pressure
#20
Satish Gurunathrao Patil, Shankargouda S Patil, Manjunatha R Aithala, Kusal Kanti Das
OBJECTIVE: Arterial aging along with increased blood pressure(BP) has become the major cardiovascular(CV) risk in elderly. The aim of the study was to compare the effects of yoga program and walking-exercise on cardiac function in elderly with increased pulse pressure (PP). METHODS: An open label, parallel-group randomized controlled study design was adopted. Elderly individuals aged ≥60 years with PP≥60mmHg were recruited for the study. Yoga (study) group (n=30) was assigned for yoga training and walking (exercise) group (n=30) for walking with loosening practices for one hour in the morning for 6days in a week for 3 months...
July 2017: Indian Heart Journal
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