keyword
https://read.qxmd.com/read/38609287/pecarn-prediction-rules-for-ct-imaging-of-children-presenting-to-the-emergency-department-with-blunt-abdominal-or-minor-head-trauma-a-multicentre-prospective-validation-study
#21
JOURNAL ARTICLE
James F Holmes, Kenneth Yen, Irma T Ugalde, Paul Ishimine, Pradip P Chaudhari, Nisa Atigapramoj, Mohamed Badawy, Kevan A McCarten-Gibbs, Donovan Nielsen, Allyson C Sage, Grant Tatro, Jeffrey S Upperman, P David Adelson, Daniel J Tancredi, Nathan Kuppermann
BACKGROUND: The intra-abdominal injury and traumatic brain injury prediction rules derived by the Pediatric Emergency Care Applied Research Network (PECARN) were designed to reduce inappropriate use of CT in children with abdominal and head trauma, respectively. We aimed to validate these prediction rules for children presenting to emergency departments with blunt abdominal or minor head trauma. METHODS: For this prospective validation study, we enrolled children and adolescents younger than 18 years presenting to six emergency departments in Sacramento (CA), Dallas (TX), Houston (TX), San Diego (CA), Los Angeles (CA), and Oakland (CA), USA between Dec 27, 2016, and Sept 1, 2021...
May 2024: Lancet Child & Adolescent Health
https://read.qxmd.com/read/38607199/effects-of-continuous-quality-improvement-on-complication-rate-and-treatment-outcome-of-extremely-premature-infants
#22
JOURNAL ARTICLE
Yang Chen, Tingting Cheng, Huaping Zhu, Shiwen Xia
BACKGROUND: Extremely premature infants (EPIs) are those less than 32 weeks of gestational age. Preterm birth is the leading cause of neonatal death and poor prognosis, accounting for 25% of neonatal deaths, with extremely premature births accounting for 50% of all premature deaths. Continuous quality improvement (CQI) improves patient outcomes by changing and optimizing clinical practice including increasing participation of neonatologists in prenatal consultation, maintenance of normal body temperature in preterm infants, early use of pulmonary surfactant, reduction of mechanical ventilation time and intensive breastfeeding to reduce clinically avoidable adverse events...
April 12, 2024: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/38601172/adrenal-infarction-with-latent-myelodysplastic-myeloproliferative-neoplasm-unclassifiable-with-jak2-v617f-mutation
#23
Shunichiro Yasuda, Momoko Chiba, Rie Nishitani, Takako Watanabe
KEY CLINICAL MESSAGE: Hematopoietic neoplasms can cause adrenal infarction. In cases of thrombosis occurring at uncommon sites, it is necessary to consider evaluating for the JAK2 V617F mutation, even in the absence of notable abnormalities in blood counts. ABSTRACT: Adrenal infarction, a rare ailment, has been sporadically linked to hematopoietic neoplasms. A 46-year-old male encountered left adrenal infarction, which coincided with a progressive rise in platelet counts...
April 2024: Clinical Case Reports
https://read.qxmd.com/read/38600621/generative-artificial-intelligence-to-produce-high-fidelity-blastocyst-stage-embryo-images
#24
JOURNAL ARTICLE
Ping Cao, Josien Derhaag, Edith Coonen, Han Brunner, Ganesh Acharya, Andres Salumets, Masoud Zamani Esteki
STUDY QUESTION: Can generative artificial intelligence (AI) models produce high-fidelity images of human blastocysts? SUMMARY ANSWER: Generative AI models exhibit the capability to generate high-fidelity human blastocyst images, thereby providing substantial training datasets crucial for the development of robust AI models. WHAT IS KNOWN ALREADY: The integration of AI into IVF procedures holds the potential to enhance objectivity and automate embryo selection for transfer...
April 10, 2024: Human Reproduction
https://read.qxmd.com/read/38600456/comparative-visual-outcomes-of-the-first-versus-second-eye-following-small-incision-lenticule-extraction-smile
#25
JOURNAL ARTICLE
Anzhen Li, Xiaowei Yang, Wei Wang, Wenbin Huang, Hui Ding, Ke Nie, Tan Zhong, Shisi Hu, Zhenduo Yang, Xingwu Zhong
BACKGROUND: This study aimed to compare the visual outcomes of the first operated eyes with those of the second operated eyes following small-incision lenticule extraction (SMILE). METHODS: A total of 202 patients (404 eyes) underwent SMILE using the tear film mark centration method for myopia and myopic astigmatism correction. Baseline characteristics, objective optical quality, decentered displacement, induced corneal aberrations, and modulation transfer function (MTF) values were assessed...
April 11, 2024: BMC Ophthalmology
https://read.qxmd.com/read/38599593/-large-language-models-for-rapid-simplification-of-quality-assurance-data-input-field-trial-with-real-data-in-the-context-of-tumour-documentation-in-urology
#26
JOURNAL ARTICLE
Johannes Frank, Axel S Merseburger, Johannes Landmesser, Silvia Brozat-Essen, Peter Schramm, Laura Freimann, Alexander Kleehaus, Christian Elsner
INTRODUCTION: Large Language Models (LLMs) such as ChatGPT have rapidly brought the application of artificial intelligence into widespread use. Among many different use cases for text generation and processing, one application is the extraction of data from existing documents and conversations for simplified and automated form-filling. OBJECTIVE: In the field of quality assurance and documentation of cancer diseases, there is currently a significant workload involved in transferring data under various aspects into slightly varying formats and applying interpretations such as the TNM classification of tumours...
April 10, 2024: Aktuelle Urologie
https://read.qxmd.com/read/38598240/claims-based-vs-agency-reported-patient-outcomes-among-home-health-agencies-2013-2019
#27
JOURNAL ARTICLE
Amanda C Chen, Christina Xiang Fu, David C Grabowski
IMPORTANCE: Given the growth of home health agency (HHA) care, it is important to understand whether quality reporting programs, such as star ratings, are associated with improved patient outcomes. OBJECTIVE: To assess the immediate and long-term association of the introduction of HHA star ratings with patient-level quality outcomes, comparing claims-based and agency-reported measures. DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional study used Medicare HHA claims and agency-reported assessments to identify sequential patient episodes (ie, spells) among US adults with traditional Medicare who received HHA care (2013-2019)...
April 1, 2024: JAMA Network Open
https://read.qxmd.com/read/38596287/emerging-therapeutic-approaches-for-peritoneal-metastases-from-gastrointestinal-cancers
#28
REVIEW
Aleksandra Sikora, Kevin M Sullivan, Sean Dineen, Mustafa Raoof, Aleksandra Karolak
Peritoneal metastases from gastrointestinal malignancies present difficult management decisions, with options consisting primarily of systemic chemotherapy or major surgery with or without hyperthermic intraperitoneal chemotherapy. Current research is investigating expanding therapeutic modalities, and the aim of this review is to provide an overview of the existing and emerging therapies for the peritoneal metastases from gastrointestinal cancers, primarily through the recent literature (2015 and newer). These include the current data with systemic therapy and cytoreduction with hyperthermic intraperitoneal or pressurized intraperitoneal aerosol chemotherapy, as well as novel promising modalities under investigation, including dominating oncolytic viral therapy and adoptive cellular, biologic, and bacteria therapy, or nanotechnology...
March 21, 2024: Mol Ther Oncol
https://read.qxmd.com/read/38596187/correction-method-for-moderate-and-severe-degrees-of-hallux-valgus-associated-with-transfer-metatarsalgia
#29
Amangasy Zhanaspayev, Nurlan Bokembayev, Marat Zhanaspayev, Aidos Tlemissov, Sabina Aubakirova, Alexander Prokazyuk
BACKGROUND: Hallux valgus (HV) is a common foot deformity that manifests with increasing age, especially in women. The associated foot pain causes impaired gait and decreases quality of life. Moderate and severe HV is a deformity that is characterized by the involvement of lesser rays and requires complex surgical treatment. In this study, we attempted to develop a procedure for this condition. AIM: To analyse the treatment results of patients who underwent simultaneous surgical correction of all parts of a static forefoot deformity...
March 18, 2024: World Journal of Orthopedics
https://read.qxmd.com/read/38596145/surgical-treatment-for-primary-lymphedema-a-systematic-review-of-the-literature
#30
JOURNAL ARTICLE
Miguel Angel Gaxiola-García, Joseph M Escandón, Oscar J Manrique, Kristin A Skinner, Beatriz Hatsue Kushida-Contreras
This is a retrospective review of surgical management for primary lymphedema. Data were extracted from 55 articles from PubMed MEDLINE, Web of Science, SCOPUS, and Cochrane Central Register of Controlled Trials between the database inception and December 2022 to evaluate the outcomes of lymphaticovenous anastomosis (LVA) and vascularized lymph node transfer (VLNT), and outcomes of soft tissue extirpative procedures such as suction-assisted lipectomy (SAL) and extensive soft tissue excision. Data from 485 patients were compiled; these were treated with LVA ( n  = 177), VLNT ( n  = 82), SAL ( n  = 102), and excisional procedures ( n  = 124)...
March 2024: Archives of Plastic Surgery
https://read.qxmd.com/read/38594945/toward-optogenetic-hearing-restoration
#31
REVIEW
Antoine Huet, Thomas Mager, Christian Gossler, Tobias Moser
The cochlear implant (CI) is considered the most successful neuroprosthesis as it enables speech comprehension in the majority of the million otherwise deaf patients. In hearing by electrical stimulation of the auditory nerve, the broad spread of current from each electrode acts as a bottleneck that limits the transfer of sound frequency information. Hence, there remains a major unmet medical need for improving the quality of hearing with CIs. Recently, optogenetic stimulation of the cochlea has been suggested as an alternative approach for hearing restoration...
April 9, 2024: Annual Review of Neuroscience
https://read.qxmd.com/read/38594694/preparing-medical-students-for-their-educational-task-as-physicians-important-desirable-and-unexplored-territory
#32
JOURNAL ARTICLE
Bas Ph Ter Brugge, Lena Sophia Fegg, Marjo Wijnen-Meijer
BACKGROUND: Physicians engage in educational activities in daily practice and take over an important role in providing information and transferring knowledge to patients and medical students. Therefore, it is important to focus on methods to develop teaching skills during medical school. Peer-teaching is a teaching method that is connected to different positive learning outcomes. This study aims to investigate the perspective of medical students regarding teaching as a core competency of physicians and peer-teaching as an opportunity to acquire educational skills...
April 9, 2024: BMC Medical Education
https://read.qxmd.com/read/38592463/a-retrospective-chart-analysis-with-5-year-follow-up-of-early-care-for-geriatric-hip-fracture-patients-why-we-should-continue-talking-about-hip-fractures
#33
JOURNAL ARTICLE
An Sermon, Evelyne Verhulst, Laurens Aerden, Harm Hoekstra
BACKGROUND: Timing of surgery remains a topic of debate for hip fracture treatment in the geriatric patient population. The quality indicator "early surgery" was implemented in 2014 at the Department of Trauma Surgery of the University Hospitals Leuven to enhance timely operative treatment. In this follow-up study, we aim to evaluate the performance of this quality indicator, the clinical outcomes, and room for improvement. METHODS: The charts of 1190 patients surgically treated for an acute hip fracture were reviewed between June 2017 and May 2022 at the University Hospitals Leuven...
April 9, 2024: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://read.qxmd.com/read/38592155/embryo-transfer-procedural-parameters-do-not-predict-ivf-cycle-outcome
#34
JOURNAL ARTICLE
Konstantinos Sfakianoudis, Evangelos Maziotis, Anna Trypidi, Sokratis Grigoriadis, Terpsithea Vaxevanoglou, Irene Angeli, Anna Rapani, Amalia Kotsifaki, Kalliopi Pistola, Agni Pantou, Konstantinos Dafopoulos, Konstantinos Pantos, Mara Simopoulou
BACKGROUND: this study aims to assess the effect of embryo transfer (ET) performance parameters of a technical nature on IVF outcome. METHODS: A total of 1417 ETs from a single IVF center were included in this prospective observational study. The parameters investigated were as follows: the presence of cervical mucus post catheter withdrawal, the presence of blood, catheter reload, the employment of a tenaculum and stylet, catheter resistance as experienced by the physician and patient discomfort...
February 26, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38591293/surfactant-protein-d-diabetes-mellitus-oxidative-stress-infections-and-inflammation-on-the-crossroad-a-systematic-review
#35
Shireen Javed, Mahaneem Mohamed, Benash Altaf, Wan Syaheedah Wan Ghazali
OBJECTIVE: To review the association of surfactant protein-D with type 2 diabetes mellitus, infections, oxidative stress and inflammation, and the changes in oxidative stress markers in type 2 diabetes mellitus. METHODS: The systematic review was conducted from April to September 2022, and comprised search on PubMed, Web of Sciences, Scopus, Science Direct and Google Scholar databases for relevant studies published in English language between January 1, 2000, and June 30, 2022...
March 2024: JPMA. the Journal of the Pakistan Medical Association
https://read.qxmd.com/read/38589897/the-use-of-positive-deviance-approach-to-improve-health-service-delivery-and-quality-of-care-a-scoping-review
#36
REVIEW
Ayelign Mengesha Kassie, Elizabeth Eakin, Biruk Beletew Abate, Aklilu Endalamaw, Anteneh Zewdie, Eskinder Wolka, Yibeltal Assefa
BACKGROUND: Quality has been a persistent challenge in the healthcare system, particularly in resource-limited settings. As a result, the utilization of innovative approaches is required to help countries in their efforts to enhance the quality of healthcare. The positive deviance (PD) approach is an innovative approach that can be utilized to improve healthcare quality. The approach assumes that solutions to problems are already available within the community and identifying and sharing those solutions can help others to resolve existing issues...
April 8, 2024: BMC Health Services Research
https://read.qxmd.com/read/38586701/a-successful-pregnancy-following-intracytoplasmic-sperm-injection-in-a-breast-cancer-survivor-a-case-report
#37
Nancy Nair, Akash More, Brij Raj Singh, Achyut Wadkar, Priyal Tilak
This report documents the case of a 36-year-old female diagnosed with stage I invasive ductal carcinoma of the left breast who, alongside her 39-year-old husband, sought fertility assistance at our center due to primary infertility. Having survived cancer twice in the span of their seven-year marriage, the couple faced the challenge of overcoming both the repercussions of cancer treatment and difficulties in conceiving. Initial attempts through three intrauterine insemination (IUI) cycles proved unsuccessful, leading the couple to opt for in vitro fertilization (IVF)...
March 2024: Curēus
https://read.qxmd.com/read/38584884/clinical-implementation-of-failure-modes-and-effects-analysis-for-gynecological-high-dose-rate-brachytherapy
#38
JOURNAL ARTICLE
Siyao Liu, Emma Jones
PURPOSE: To use failure modes and effects analysis (FMEA) to identify failure modes for gynecological high-dose-rate (HDR) brachytherapy pathway and score with severity, occurrence, and detectability. MATERIAL AND METHODS: A research team was organized to observe gynecological HDR brachytherapy pathway, and draw detailed process map to identify all potential failure modes (FMs). The whole team scored FMs based on three parameters, including occurrence (O), detectability (D), and severity (S), and then multiplied three scores to obtain risk priority number (RPN)...
February 2024: Journal of Contemporary Brachytherapy
https://read.qxmd.com/read/38582904/delayed-discharge-in-inpatient-psychiatric-care-a-systematic-review
#39
REVIEW
Ashley-Louise Teale, Ceri Morgan, Tom A Jenkins, Pamela Jacobsen
BACKGROUND: Delayed discharge is problematic. It is financially costly and can create barriers to delivering best patient care, by preventing return to usual functioning and delaying admissions of others in need. This systematic review aimed to collate existing evidence on delayed discharge in psychiatric inpatient settings and to develop understanding of factors and outcomes of delays in these services. METHODS: A search of relevant literature published between 2002 and 2022 was conducted on Pubmed, PsycInfo and Embase...
April 6, 2024: International Journal of Mental Health Systems
https://read.qxmd.com/read/38581372/dual-activated-h-2-o-2-responsive-aie-probes-for-oocyte-quality-assessment
#40
JOURNAL ARTICLE
Xiyuan Dong, Hanzhi Ouyang, Xiaoding Lou, Fan Xia, Lei Jin, Shixuan Wang, Jun Dai
Nonobstructive azoospermia (NOA) is an important cause of infertility, and intracytoplasmic sperm injection (ICSI) is the mainstay of treatment for these patients. In cases where a sufficient number of sperm (usually 1-2) is not available, the selection of oocytes for ICSI is a difficult problem that must be solved. Here, we constructed a dual-activated oxidative stress-responsive AIE probe, b-PyTPA. The strong donor-acceptor configuration of b-PyTPA leads to twisted intramolecular charge transfer (TICT) effect that quenches the fluorescence of the probe, however, H2 O2 would specifically remove the boronatebenzyl unit and release a much weaker acceptor, which inhibits TICT and restores the fluorescence...
April 6, 2024: Analytical Chemistry
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