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https://www.readbyqxmd.com/read/28528021/multicystic-peritoneal-mesothelioma-a-short-review
#1
Chi-Hao Zhang, Ji-Wei Yu, Meng Luo
Multicystic peritoneal mesothelioma (MCPM) is a rare neoplasm, predominantly affecting female patients during their reproductive years. The lesion is usually distributed diffusely in the abdomen and pelvis, but the peritoneum of the pelvic organs is the most common site. MCPM is composed of fluid-filled translucent cysts, connected by varying amounts of fibrous tissue, and lined by a layer of mesothelial cells. Because of the rarity of this disease, the pathogenesis and natural history of MCPM remain poorly understood and continuously debated...
March 31, 2017: Current Problems in Cancer
https://www.readbyqxmd.com/read/28509715/epidemic-of-isothiazolinone-allergy-in-north-america-prevalence-data-from-the-north-american-contact-dermatitis-group-2013-2014
#2
Matthew J Zirwas, Dathan Hamann, Erin M Warshaw, Howard I Maibach, James S Taylor, Denis Sasseville, Joel G DeKoven, Anthony F Fransway, C G Toby Mathias, Kathryn A Zug, Vincent A DeLeo, Joseph F Fowler, James G Marks, Melanie D Pratt, Donald V Belsito
BACKGROUND: Preservative sensitivity patterns evolve with changing use patterns in products. During the last decade, the use of methylisothiazolinone (MI) at higher concentrations in both leave-on and rinse-off products has significantly increased. This is the first North American Contact Dermatitis Group reporting cycle that includes both methylchloroisothiazolinone (MCI)/MI and MI data. OBJECTIVE: The aim of this study was to report the prevalence of isothiazolinone allergy (MCI/MI and MI) in the North American Contact Dermatitis Group patch-test population from January 1, 2013, to December 31, 2014...
May 2017: Dermatitis
https://www.readbyqxmd.com/read/28507470/evaluating-the-relationship-of-blood-pressure-plasma-angiotensin-peptides-and-aldosterone-with-cognitive-functions-in-patients-with-hypertension
#3
Selçuk Sen, Nermin Gürel, Baran Ufuktepe, Zeynep Günes Özünal, Çagla Büyüklü, Yagiz Üresin
Renin Angiotensin Aldosterone System (RAAS) plays an important role in the development of hypertension. On the other hand, hypertension is a well-known and independent risk factor for cognitive impairment. The aim of the present study was to evaluate the relationship of blood pressure control, plasma angiotensin peptides and aldosterone with cognitive functions. Forty-one patients who were under treatment with the same antihypertensive medications for at least three months were included in the study. Plasma angiotensin II, angiotensin 1-7, angiotensin IV, and aldosterone concentrations were analyzed using an enzyme-linked immunosorbent assay (ELISA)...
2017: EXCLI journal
https://www.readbyqxmd.com/read/28501580/can-the-acute-mri-features-reflect-neurological-prognosis-in-patients-with-cervical-spinal-cord-injury
#4
Akinobu Matsushita, Takeshi Maeda, Eiji Mori, Itaru Yuge, Osamu Kawano, Takayoshi Ueta, Keiichiro Shiba
BACKGROUND CONTEXT: Several prognostic studies looked for an association between the degree of SCI, as depicted by primary MRI within 72 hours of injury, and neurologic outcome.It was not clearly demonstrated whether the MRI at any time is to correlate with neurological prognosis. PURPOSE: The purpose of the present study was to investigate the relationship between the acute MRI features and neurological prognosis, especially walking ability of patients with cervical spinal cord injury (CSCI)...
May 10, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28499344/the-responsiveness-and-minimal-important-change-mic-of-the-western-ontario-shoulder-instability-index-wosi-and-oxford-shoulder-instability-score-osis
#5
Just A van der Linde, Derk A van Kampen, Loes W A H van Beers, Derek F P van Deurzen, Daniël B F Saris, Caroline B Terwee
Study Design A prospective cohort study. Background Patient Reported Outcome Measurements (PROMs) are widely used to evaluate functional limitations. Considering PROMs for shoulder instability, information is lacking with regard to what constitutes a relevant change from baseline scores. Objectives To evaluate the responsiveness of the Western Ontario Shoulder Instability Index (WOSI) and the Oxford Shoulder Instability Score (OSIS) and estimate their Minimal Important Change (MIC). Methods 105 consecutive patients with shoulder instability completed five PROMs at baseline and at 6-months follow-up...
May 12, 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28496293/the-effect-of-dopaminergic-medication-on-joint-kinematics-during-haptic-movements-in-individuals-with-parkinson-s-disease
#6
Kuan-Yi Li, Pei-Yi Chu, Kristen A Pickett
This study examined whether altered joint angular motion during haptic exploration could account for a decline in haptic sensitivity in individuals with PD by analyzing joint position data during haptic exploration of a curved contour. Each participant's hand was passively moved by a robotic arm along the edges of a virtual box (5 cm × 15 cm) with a curved left wall. After each trial, participants indicated whether the contour was curved or straight. Visual, auditory, and tactile cues were occluded, and an electrogoniometer recorded shoulder and elbow joint angles during each trial...
2017: Behavioural Neurology
https://www.readbyqxmd.com/read/28488507/how-to-assist-patients-with-sit-stand-transfers
#7
Janice Taylor
Rationale and key points This article discusses optimal methods for assisting patients with sit-stand transfers where moving-and-handling equipment is not required. The article explains the importance of effective mobility care in optimising patients' rehabilitation and enhancing their independence. » The term 'assistance' is used in this article to refer to the support nurses can provide to patients during sit-stand transfers, but excludes manual assistance. Nurses should attempt various 'hands-off' mobility-enhancing strategies to assist the patient, such as the use of verbal, visual or light manual cues...
May 10, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28484860/anatomic-study-of-the-first-extensor-compartment-and-the-relationship-between-the-extensor-tendon-width-and-its-distal-insertion
#8
Shiro Sugiura, Yusuke Matsuura, Kazuki Kuniyoshi, Satoru Nishikawa, Takeshi Toyooka, Chisato Mori, Takane Suzuki
INTRODUCTION: The extensor pollicis brevis (EPB) tendon normally inserts into the base of the proximal phalanx of the thumb. However, a distal insertion of the EPB tendon into the thumb interphalangeal joint has been reported in refractory cases of de Quervain's disease. We hypothesized that the EPB tendon is wider beyond the thumb metacarpophalangeal joint in patients with extended EPB. This study aimed to evaluate the relationship between the extensor tendon width and the point of distal insertion of the EPB tendon...
May 8, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28483276/effectiveness-of-finger-marker-for-maintaining-the-correct-compression-point-during-paediatric-resuscitation-a-simulation-study
#9
Jae Yun Jung, Young Ho Kwak, Hyuksool Kwon, Yoo Jin Choi, Do Kyun Kim, Hee Chan Kim, Jung Chan Lee, Ji Heum Park, Hyungsoo Lim
OBJECTIVE: High-quality cardiopulmonary resuscitation is a significant factor for increasing the survival rate of paediatric patients. This study is to investigate the effectiveness of finger-marker stickers for maintaining the correct compression point during simulated infant cardiopulmonary resuscitation (CPR). METHODS: This crossover simulation study was conducted with 40 emergency physicians and paramedics at emergency departments of 2 tertiary hospitals. We used a remodeled infant CPR manikin developed to measure CPR quality indicators...
April 11, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28480195/alpha-interferon-treatment-in-hepatitis-b
#10
REVIEW
Aaron Shu Jeng Woo, Raymond Kwok, Taufique Ahmed
Pegylated interferon-α (PEG-IFN-α) is a first line option in the treatment of chronic hepatitis B. Compared with nucleos(t)ide analogues (NAs), therapy with PEG-IFN-α has the advantages of finite treatment duration and higher rates of hepatitis B surface antigen (HBsAg) and hepatitis B e antigen (HBeAg) seroconversion, but the disadvantage of greater adverse effects. Choosing PEG-IFN-α requires careful evaluation of the likelihood of achieving a sustained off-treatment response. Sustained off-treatment response with PEG-IFN-α can be predicted by baseline factors in HBeAg positive disease...
April 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28469889/a-quality-improvement-approach-to-standardization-and-sustainability-of-the-hand-off-process
#11
Craig Fryman, Carine Hamo, Siddharth Raghavan, Nirvani Goolsarran
There is mounting evidence that communication and hand-off failures are a root cause of two-thirds of sentinel events in hospitals. Several studies have shown that non-standardized hand-offs have yielded poor patient outcomes and adverse events. At Stony Brook University Hospital, there were numerous reported adverse events related to poor hand-off during the transfer of patient responsibility from one resident caregiver to the next. A resident-conducted root cause analysis identified lack of a standardized hand-off process and formal training on safe and efficient hand-off among caregivers as key contributing factors...
2017: BMJ Quality Improvement Reports
https://www.readbyqxmd.com/read/28458971/successful-arthroplasty-using-cadaveric-meniscus-for-osteochondral-defects-in-the-wrist-and-hand-joints
#12
Don Hoang, Vivi W Chen, Daniel J Gould, Myles J Cohen, David A Kulber
BACKGROUND: Osteochondral defects of the radiocarpal, metacarpophalangeal (MCP), and proximal interphalangeal (PIP) joints often necessitate joint arthrodesis or mechanical arthroplasty, which has a limited lifespan. In severely arthritic wrist and finger joints, we propose a novel adjunct for joint salvage using cadaveric meniscus for joint resurfacing as an off-the-shelf alternative to address osteochondral defects and restore normal intraarticular contact stress. METHODS: A total of 14 patients with osteochondral defects in 5 radiocapitate, 5 MCP, 3 PIP, and 1 carpometacarpal joints received cadaveric meniscus to facilitate arthroplasty...
March 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28456539/role-of-preoperative-testicular-shear-wave-elastography-in-predicting-improvement-of-semen-parameters-after-varicocelectomy-for-male-patients-with-primary-infertility
#13
Khaled Abdelwahab, Ahmed M Eliwa, Mohammed M Seleem, Hazem El Galaly, Ahmed Ragab, Esam A Desoky, Mohamed Naguib, Maged M Ali, Sameh Saber, Hussain Kamel
OBJECTIVES: To evaluate the role of preoperative testicular Shear wave elastography in prediction of improvement of semen analysis parameters after subinguinal microsurgical varicocele ligation in patients with primary infertility and clinically detectable varicocele. PATIENTS AND METHODS: Testicular Shear wave elastography (SWE) before the surgical intervention was done. Forty eight patients were scheduled for subinguinal microsurgical varicocele ligation as treatment option...
April 26, 2017: Urology
https://www.readbyqxmd.com/read/28455740/motor-equivalence-and-structure-of-variance-multi-muscle-postural-synergies-in-parkinson-s-disease
#14
Ali Falaki, Xuemei Huang, Mechelle M Lewis, Mark L Latash
We explored posture-stabilizing multi-muscle synergies with two methods of analysis of multi-element, abundant systems: (1) Analysis of inter-cycle variance; and (2) Analysis of motor equivalence, both quantified within the framework of the uncontrolled manifold (UCM) hypothesis. Data collected in two earlier studies of patients with Parkinson's disease (PD) were re-analyzed. One study compared synergies in the space of muscle modes (muscle groups with parallel scaling of activation) during tasks performed by early-stage PD patients and controls...
April 28, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28455081/optimizing-postpartum-care-for-the-patient-with-gestational-diabetes-mellitus
#15
Noelle G Martinez, Charlotte M Niznik, Lynn M Yee
Gestational diabetes mellitus (GDM) poses well-established risks to both the mother and infant. As over 50% of women with GDM will develop type 2 diabetes mellitus (T2DM) in their lifetime, performing postpartum oral glucose tolerance testing (OGTT) is paramount to initiation of appropriate lifestyle interventions and pharmacologic therapy. Nonetheless, test completion among women with GDM is estimated to be <50%, with particularly low rates in Latina patients, as well as patients with public insurance, low education levels, and low health literacy...
April 25, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28452917/quality-of-handoffs-in-community-pharmacies
#16
Ephrem Abebe, Jamie A Stone, Corey A Lester, Michelle A Chui
OBJECTIVES: The aims of the study were to characterize handoffs in community pharmacies and to examine factors that contribute to perceived handoff quality. METHODS: A cross-sectional study of community pharmacists in a Midwest State of the United States. Self-administered questionnaires were used to collect information on participant and practice setting characteristics. Data were analyzed using descriptive statistics and multivariate logistic regression. RESULTS: A total of 445 completed surveys were returned (response rate, 82%)...
April 27, 2017: Journal of Patient Safety
https://www.readbyqxmd.com/read/28449852/radiation-exposure-during-intramedullary-nailing
#17
David J Hak
Surgeons should aim to keep radiation exposure "As Low As Reasonably Achievable (ALARA)" during intramedullary nailing and other minimally invasive surgical procedures. This requires understanding the principles of ionizing radiation and methods for minimizing exposure risk. The main source of radiation exposure to surgical personnel during fluoroscopy is from scattered radiation. Since radiation scatter is mainly directed towards the fluoroscopy source, the best configuration during surgery to reduce radiation dose to the surgeon is to position the fluoroscopic source below the operating room table and the image collector above the table...
April 24, 2017: Injury
https://www.readbyqxmd.com/read/28437161/randomized-phase-iii-trial-of-trastuzumab-plus-capecitabine-with-or-without-pertuzumab-in-patients-with-human-epidermal-growth-factor-receptor-2-positive-metastatic-breast-cancer-who-experienced-disease-progression-during-or-after-trastuzumab-based-therapy
#18
Ander Urruticoechea, Mohammed Rizwanullah, Seock-Ah Im, Antonio Carlos Sánchez Ruiz, István Láng, Gianluca Tomasello, Hannah Douthwaite, Tanja Badovinac Crnjevic, Sarah Heeson, Jennifer Eng-Wong, Montserrat Muñoz
Purpose To assess the efficacy and safety of trastuzumab plus capecitabine with or without pertuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer who experienced disease progression during or after trastuzumab-based therapy and received a prior taxane. Patients and Methods Patients were randomly assigned to arm A: trastuzumab 8 mg/kg → 6 mg/kg once every 3 weeks plus capecitabine 1,250 mg/m(2) twice a day (2 weeks on, 1 week off, every 3 weeks); or arm B: pertuzumab 840 mg → 420 mg once every 3 weeks plus trastuzumab at the same dose and schedule as arm A plus capecitabine 1,000 mg/m(2) on the same schedule as arm A...
April 24, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28435568/early-vessels-exploration-of-pink-pulseless-hand-in-gartland-iii-supracondylar-fracture-humerus-in-children-facts-and-controversies
#19
T Z Tunku-Naziha, Wms Wan-Yuhana, D Hadizie, Muhammad-Paiman, S Abdul-Nawfar, W S Wan-Azman, M S Arman-Z, S Abdul-Razak, M Z Rhendra-Hardy, W I Wan-Faisham
The management of pink pulseless limbs in supracondylar fractures has remained controversial, especially with regards to the indication for exploration in a clinically well-perfused hand. We reviewed a series of seven patients who underwent surgical exploration of the brachial artery following supracondylar fracture. All patients had a non-palpable radial artery, which was confirmed by Doppler ultrasound. CT angiography revealed complete blockage of the artery with good collateral and distal run-off. Two patients were more complicated with peripheral nerve injuries, one median nerve and one ulnar nerve...
March 2017: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/28435494/the-efficacy-of-lucas-in-prehospital-cardiac-arrest-scenarios-a-crossover-mannequin-study
#20
Robert A Gyory, Scott E Buchle, David Rodgers, Jeffrey S Lubin
INTRODUCTION: High-quality cardiopulmonary resuscitation (CPR) is critical for successful cardiac arrest outcomes. Mechanical devices may improve CPR quality. We simulated a prehospital cardiac arrest, including patient transport, and compared the performance of the LUCAS™ device, a mechanical chest compression-decompression system, to manual CPR. We hypothesized that because of the movement involved in transporting the patient, LUCAS would provide chest compressions more consistent with high-quality CPR guidelines...
April 2017: Western Journal of Emergency Medicine
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