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https://www.readbyqxmd.com/read/28214180/a-successful-experience-of-the-iranian-blood-transfusion-organization-in-improving-accessibility-and-affordability-of-plasma-derived-medicine
#1
REVIEW
Azita Chegini, Seyed Ardeshir Torab, Ali Akbar Pourfatollah
Plasma is the liquid part of blood. It is estimated 21.6 million liters of plasma collect from Whole blood annually. From these plasma, 4.2 million liters transfuse, 8.1 million liters fractionate, 9.3 million liters waste. Nowadays, blood products and PDM (plasma derived medicine) consider as essential medicine in modern health care and transfusion medicine. Iranian blood transfusion organization as a non-profit organization was established in 1974 in order to centralize all blood transfusion activities from donor recruitment to distribution of blood components to hospitals...
January 4, 2017: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/28111924/awareness-of-cord-blood-collection-and-the-impact-on-banking
#2
Rusha Bhandari, Amy Lindley, Deepika Bhatla, Aleksandar Babic, Kathy Mueckl, Rakesh Rao, Paula Brooks, Vicki Geiler, Gilad Gross, Mohamad Al-Hosni, Shalini Shenoy
BACKGROUND: Umbilical cord blood (UCB) is an important source of hematopoietic stem cells for transplantation especially in minority populations with limited chances of finding a histocompatible volunteer donor in the registry. UCB has the advantages of early availability, successful outcomes despite some histocompatibility mismatch, and low incidence of chronic graft-versus-host disease. Public cord blood banks that disseminate UCB products for transplant depend on voluntary donation at participating hospitals and obstetrical providers for collection...
January 23, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28100266/arranging-blood-for-elective-thyroid-surgeries-dilemma-continues-in-the-developing-world
#3
Salman Faridi, Aman Ahmad, Mirza Arshad Beg, Faisal Siddiqui, Muhammad Muzzammil Edhi, Mehmood Khan
BACKGROUND: Cross matched blood is frequently ordered based on a subjective anticipation of blood loss for a procedure. Excessive blood arrangement and wastage overburdens the blood bank in terms of work load and storage of blood, increases cost of medical care and results in injudicious use of a limited resource. The aim of this short report is to assess the current practice for arranging cross matched blood in elective thyroid surgeries by comparing cross match to blood transfused ratio...
January 18, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28003931/stability-of-thawed-apheresis-fresh-frozen-plasma-stored-for-up-to-120-hours-at-1%C3%A2-c-to-6%C3%A2-c
#4
William P Sheffield, Varsha Bhakta, Qi-Long Yi, Craig Jenkins
Regulations concerning the storage of transfusable plasma differ internationally. In Canada, plasma obtained from whole blood donations and frozen within 24 hours of phlebotomy (frozen plasma, FP) may be thawed and transfused within 120 hours of refrigerated storage. However, plasma frozen within 8 hours of phlebotomy following apheresis donation (FFPA) must be transfused within 24 hours of thawing and refrigeration. Our objectives were to measure coagulation factors (F) V, VII, and VIII, fibrinogen activities, and the prothrombin time (PT) in thawed refrigerated FFPA at 0, 24, and 120 hours of storage and to compare these values to those in thawed refrigerated FP...
2016: Journal of Blood Transfusion
https://www.readbyqxmd.com/read/27892437/blood-requisition-and-utilization-practice-in-surgical-patients-in-a-teaching-hospital-western-nepal
#5
O B Karki
Background In surgical patients transfusion of blood is often a life-saving measure. Preoperative over-ordering of blood is very common and leads to holding up of the blood bank reserve and wastage of resources. Objective The main objective of this study was to evaluate the practice of cross-match and utilization of blood for general surgeries in a teaching hospital of Nepal, to identify the surgical procedures where type and screen can be introduced and to formulate a maximum surgical blood-order schedule for those procedures where a complete cross-match appears mandatory...
January 2016: Kathmandu University Medical Journal (KUMJ)
https://www.readbyqxmd.com/read/27850802/1165-massive-transfusion-protocol-in-a-community-nontrauma-setting-is-blood-product-wastage-avoidable
#6
Noubar Kevorkian, Sharon Weintraub, Nancy Bienkowski, Peg Basch, Stacy Pagliaruli, Susan Parker, Jacobs Barry, Rekha Singh
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27788406/acceptability-of-low-dead-space-syringes-and-implications-for-their-introduction-a-qualitative-study-in-the-west-of-england
#7
Joanna M Kesten, Rachel Ayres, Jane Neale, Jody Clark, Peter Vickerman, Matthew Hickman, Sabi Redwood
BACKGROUND: It is recommended that needle and syringe programmes (NSP) distribute low dead space syringes (LDSS) to reduce blood-borne virus transmission. We explored the acceptability of detachable LDSS among people who inject drugs (PWID) and staff who work to support them. METHODS: Semi-structured interviews were performed with 23 PWID (15 men and 8 women) and 13 NSP staff members (6 men and 7 women) in Bath and Bristol, England. Recruited PWID reflected varying demographic characteristics, drug use and injecting preferences...
January 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/27774614/blood-component-transfusion-and-wastage-rates-in-the-setting-of-massive-transfusion-in-three-regional-trauma-centers
#8
Nancy M Dunbar, Nicholas J Olson, Zbigniew M Szczepiorkowski, Eric D Martin, Ryan M Tysarcyk, Darrell J Triulzi, Louis H Alarcon, Mark H Yazer
BACKGROUND: The purpose of massive transfusion protocols (MTPs) is to provide large quantities of blood products rapidly to exsanguinating patients. The expected rates of blood product transfusion and wastage in this setting have not been defined. This study was undertaken to assess the transfusion and wastage rates for bleeding patients requiring emergency issue of blood components at three American Level I trauma centers. STUDY DESIGN AND METHODS: Three hospitals participated, all of which are Level I trauma centers that have MTPs in place where uncrossmatched red blood cells (RBCs) can be ordered with or without platelets (PLTs), plasma, and cryoprecipitate...
January 2017: Transfusion
https://www.readbyqxmd.com/read/27766692/differential-expression-of-isg-15-mrna-in-peripheral-blood-mononuclear-cells-of-nulliparous-and-multiparous-pregnant-versus-non-pregnant-bos-indicus-cattle
#9
N P Soumya, D N Das, S Jeyakumar, S Mondal, A Mor, U T Mundhe
Embryonic mortality is found to be the main source of reproductive wastage in domestic ruminants. Many genes are involved in the growth and development of the embryo, and the interferon-stimulated gene 15 (ISG 15) is one of the major gene stimulated by interferon tau, the maternal recognition of pregnancy signal in ruminants. In this study, both genomic and cDNA sequences of ISG 15 from Bos indicus (Deoni breed) were amplified and characterized. The genomic sequence of Deoni ISG 15 exhibited 99% identity with Bos taurus and 97% identity with that of Bos mutus and Bubalus bubalis...
October 21, 2016: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/27604542/multi-method-assessment-of-patients-with-febrile-illness-reveals-over-diagnosis-of-malaria-in-rural-uganda
#10
Ria R Ghai, Mary I Thurber, Azza El Bakry, Colin A Chapman, Tony L Goldberg
BACKGROUND: Health clinics in rural Africa are typically resource-limited. As a result, many patients presenting with fever are treated with anti-malarial drugs based only on clinical presentation. This is a considerable issue in Uganda, where malaria is routinely over-diagnosed and over-treated, constituting a wastage of resources and an elevated risk of mortality in wrongly diagnosed patients. However, rapid diagnostic tests (RDTs) for malaria are increasingly being used in health facilities...
September 7, 2016: Malaria Journal
https://www.readbyqxmd.com/read/27600298/profiling-clinical-platelet-and-plasma-use-to-inform-blood-supply-and-contingency-planning-puppy-the-prospective-utilization-of-platelets-and-plasma-study
#11
Pasquale L Fedele, Mark N Polizzotto, George Grigoriadis, Neil Waters, Mary Comande, Marija Borosak, David Portbury, Erica M Wood
BACKGROUND: Demand for platelet (PLT) and plasma transfusions is increasing. Improved clinical supply and contingency planning requires greater understanding of usage profiles and urgency of clinical requirement. STUDY DESIGN AND METHODS: This study was a random-sample survey of PLT and plasma units produced in Victoria, Australia, to determine product disposition, recipient demographics, clinical indications for transfusion, and urgency (or "deferability") of need...
October 2016: Transfusion
https://www.readbyqxmd.com/read/27549418/antiphospholipid-antibodies-among-pregnant-women-with-recurrent-fetal-wastage-in-a-tertiary-hospital-in-northern-nigeria
#12
Zubaida Garba Abdullahi, Mohammmed A Abdul, Sirajo M Aminu, Bolanle O P Musa, Lawal Amadu, El-Bashir M Jibril
CONTEXT: The association between antiphospholipid antibodies (APAs) and pregnancy loss has been established and now considered as a treatable cause of pregnancy loss. Data on the prevalence of APA in patients with recurrent pregnancy loss are scarce in our environment. AIMS: To determine the prevalence of APA in pregnant women with and without recurrent fetal wastage. SETTINGS AND DESIGN: Antenatal clinic of Ahmadu Bello University Teaching Hospital, Zaria, Nigeria...
July 2016: Annals of African Medicine
https://www.readbyqxmd.com/read/27511318/effective-implementation-of-a-patient-blood-management-programme-for-platelets
#13
M Sekhar, S Clark, R Atugonza, A Li, Z Chaudhry
OBJECTIVES: To implement a patient blood management (PBM) programme in platelet transfusion. AIMS: To improve the appropriate use of blood components, reduce wastage and generate savings. BACKGROUND: PBM is a multidisciplinary, evidence-based approach to optimising the care of patients who need blood transfusion and to use blood products appropriately. Strategies for PBM ensure that patients receive the best possible treatment with the transfusion of components when indicated, at the same time avoiding or reducing unnecessary transfusions...
December 2016: Transfusion Medicine
https://www.readbyqxmd.com/read/27417340/therapeutic-monitoring-of-the-immuno-modulating-drugs-in-systemic-lupus-erythematosus
#14
Chi Chiu Mok
Despite the emergence of newer immunomodulating agents for systemic lupus erythematosus (SLE), a substantial proportion of patients still do not respond optimally. While the mechanisms for the differential responses to drug therapy are unclear, variation in drug exposure with the same dosing protocol related to pharmacogenetic and pharmacokinetic factors may contribute. This article discusses the use of therapeutic drug monitoring (TDM) to optimize therapies in SLE patients. Areas covered: Evidence on the relationship between blood levels and efficacy/toxicity of immuno-modulating drugs such as hydroxychloroquine (HCQ), mycophenolate mofetil (MMF) and the calcineurin inhibitors that are often used in SLE...
January 2017: Expert Review of Clinical Immunology
https://www.readbyqxmd.com/read/27297566/a-study-on-blood-product-usage-and-wastage-at-the-public-hospital-guyana
#15
Rajini Kurup, Audrey Anderson, Cecil Boston, Lynn Burns, Marian George, Marana Frank
BACKGROUND: Blood is a valuable resource and blood wastage in a low socio economic country could impose a very serious impact on healthcare. This study therefore analyzes the usage and wastage of blood and blood products at the Georgetown Public Hospital Cooperation (GPHC), Guyana. METHODS: A retrospective study was conducted on the data retrieved from laboratory blood banking information system on usage and wastage of blood products during the years 2012-2014 at the public hospital...
June 13, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27146617/the-use-of-transfusion-quality-indicators-as-a-tool-for-hemovigilance-system-implementation-at-a-tertiary-care-center-in-saudi-arabia
#16
Salwa I Hindawi, Maha A Badawi, Edwin T Raj, Kholoud A Gholam, Seraj O Al-Weail, Fatima Azher
OBJECTIVES: To report 2-years experience of using transfusion-related quality indicators as a tool in hemovigilance system implementation.  METHODS: The study was carried out between 2012 and 2013. Blood transfusion service data were prospectively collected at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. Donor reactions, transfusion reactions, fresh frozen plasma (FFP) in-date wastage, incidents, and errors pertaining to orders, or requests were collected quarterly and prospectively and forwarded to the Hospital Transfusion Committee (HTC) for review...
May 2016: Saudi Medical Journal
https://www.readbyqxmd.com/read/27127742/segregation-of-blood-inventory-a-key-driver-for-optimum-blood-stock-management-in-a-resource-poor-setting
#17
Ravneet Kaur Bedi, Kshitija Mittal, Tanvi Sood, Paramjit Kaur, Gagandeep Kaur
BACKGROUND: Blood inventory management entails maintaining a delicate balance between guaranteeing blood availability and minimizing wastage. The study was conducted to identify and analyze various factors of wastage which can provide insight to ideal inventory management, thus help in formulating policies and improve efficiency of blood transfusion services. MATERIALS AND METHODS: The study was conducted in a tertiary care hospital. To determine various causes of wastage, a retrospective analysis was done over 6 months and preventive strategies adopted...
April 2016: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/27111494/are-the-rules-for-times-in-set-up-and-duration-of-red-cell-transfusion-too-strict
#18
K Foley, D Poles, H Mistry, A Gray, P H B Bolton-Maggs
OBJECTIVES: To discover if any adverse clinical effects have been reported to the UK haemovigilance scheme, Serious Hazards of Transfusion (SHOT) relating to delays in set up of transfusion or extended transfusion time for red cell units. BACKGROUND: Current guidance for duration of transfusion is based on outdated studies that do not reflect current UK Blood Service practices. Recent evidence suggests that the '30-min rule' could be extended without adverse effects...
June 2016: Transfusion Medicine
https://www.readbyqxmd.com/read/27011668/role-of-national-accreditation-board-of-hospitals-and-healthcare-providers-nabh-core-indicators-monitoring-in-quality-and-safety-of-blood-transfusion
#19
Anshu Gupta, Chhavi Gupta
CONTEXT: Certain quality indicators are mandatory in the maintenance and improvement of quality in blood transfusion. Monitoring of such indicators should be done regularly and deficiencies are to be corrected for effective blood transfusion services. AIMS: To study the usefulness of monitoring of the National Accreditation Board for Hospitals and Healthcare Providers (NABH) core indicators in blood transfusion and in the maintenance of hemovigilance. SETTINGS AND DESIGN: Hemovigilance is a quality process to improve quality and increase the safety of blood transfusion...
January 2016: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/26894224/a-survey-of-blood-request-versus-blood-utilization-at-a-university-hospital-in-iran
#20
Arash Peivandi Yazdi, Mohammad Alipour, Seyyed Saeed Jahanbakhsh, Mohammad Gharavifard, Mehryar Taghavi Gilani
BACKGROUND: Reservation of blood leads to blood wastage if the blood is not transfused. Therefore, in some centers only blood type and screen are evaluated. In this study, the efficacy of a blood crossmatch-to-transfusion ratio was measured and then compared with the standard levels. METHODS: This prospective study was conducted during one year in a university hospital. During this period, 398 patients for whom blood had been requested were studied. In these patients, at the first surgical type, the laboratory tests (hematocrit, hemoglobin, platelet count, and prothrombin time) and the number of preoperative crossmatched and intraoperative transfused blood units were recorded...
January 2016: Archives of Bone and Joint Surgery
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