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"Anaerobic threshold"

Wojciech Kosmala, Aleksandra Rojek, Monika Przewlocka-Kosmala, Leah Wright, Andrzej Mysiak, Thomas H Marwick
BACKGROUND: Impaired functional capacity is a hallmark of patients with heart failure with preserved ejection fraction (HFpEF). Despite the association of HFpEF with reduced myocardial compliance attributed to fibrosis, spironolactone has not been shown to alter outcomes-perhaps reflecting the heterogeneity of underlying pathological mechanisms. OBJECTIVES: The authors sought to identify improvement in exercise capacity with spironolactone in the subset of patients with HFpEF with exercise-induced increase in ratio between early mitral inflow velocity and mitral annular early diastolic velocity (E/e') reflecting elevation of left ventricular (LV) filling pressure...
October 25, 2016: Journal of the American College of Cardiology
Ratko Peric, Marco Meucci, Zoran Nikolovski
BACKGROUND: This study examined substrate oxidation at high-intensity exercise and aimed to determine when fat oxidation ends (FATmin). We hypothesized the existence of a connection between the anaerobic threshold (AnT) and FATmin point. METHODS: Breath-by-breath data obtained from indirect calorimetry during a graded treadmill test were used to measure substrate oxidation and maximal oxygen uptake (VO2max) on 47 males (30 athletes (ATL) and 17 non-athletes (NATL))...
December 2016: Sports Medicine—Open
Zach Rozenbaum, Shafik Khoury, Galit Aviram, Yaniv Gura, Jack Sherez, Avi Man, Jason Shimiaie, Thierry Le Tourneau, Amir Halkin, Simon Biner, Gad Keren, Yan Topilsky
BACKGROUND: Discriminating circulatory problems with reduced stroke volume from de-conditioning in which the muscles cannot consume O2 normally by gas exchange parameters is difficult. METHODS: We performed combined stress echo and cardio-pulmonary (CPET) tests in 110 patients (20 normal effort capacity, 54 attenuated stroke volume response, 36 de-conditioning) to evaluate multiple hemodynamic parameters and oxygen content difference (A-VO2 Difference) in four predefined activity levels to assess which of the gas measures may help in the discrimination...
October 11, 2016: Chest
Ludovic Giloteaux, Maureen R Hanson, Betsy A Keller
BACKGROUND Patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) present with profound fatigue, flu-like symptoms, pain, cognitive impairment, orthostatic intolerance, and post-exertional malaise (PEM), and exacerbation of some or all of the baseline symptoms. CASE REPORT We report on a pair of 34-year-old monozygotic twins discordant for ME/CFS, with WELL, the non-affected twin, and ILL, the affected twin. Both twins performed a two-day cardiopulmonary exercise test (CPET), pre- and post-exercise blood samples were drawn, and both provided stool samples for biochemical and molecular analysis...
October 10, 2016: American Journal of Case Reports
T S Nobre, R V Groehs, L F Azevedo, L M Antunes-Correa, D G Martinez, M J N N Alves, C E Negrao
It remains unknown whether or not a reduction in muscle sympathetic nerve activity in heart failure patients is associated over time with the effects of long- or short-term repeated exercise. 10 chronic heart failure patients, age 49±3 years old, functional class I-III NYHA, ejection fraction <40% were randomly submitted to either an acute bout of moderate continuous exercise OR high-intensity interval exercise. Muscle sympathetic nerve activity (microneurography) and forearm blood flow (venous occlusion plethysmography) were evaluated pre- and post-exercise sessions...
September 27, 2016: International Journal of Sports Medicine
Bryan H Goldstein, Elaine M Urbina, Philip R Khoury, Zhiqian Gao, Michelle A Amos, Wayne A Mays, Andrew N Redington, Bradley S Marino
BACKGROUND: Fontan survivors demonstrate diminished vascular function and functional outcomes, but the relationships between these measures have not been established. METHODS AND RESULTS: We performed a cross-sectional study of 60 Fontan survivors (52% male) with a mean age of 13.9±4.1 years and mean Fontan duration of 9.9±4.2 years. Multimodality assessment of endothelial function (reactive hyperemia index and flow-mediated dilation) and arterial stiffness (augmentation index and baseline pulse amplitude) was performed with peripheral arterial tonometry and brachial flow-mediated dilation...
2016: Journal of the American Heart Association
Jittima Saengsuwan, Lucia Berger, Corina Schuster-Amft, Tobias Nef, Kenneth J Hunt
BACKGROUND: Exercise testing devices for evaluating cardiopulmonary fitness in patients with severe disability after stroke are lacking, but we have adapted a robotics-assisted tilt table (RATT) for cardiopulmonary exercise testing (CPET). Using the RATT in a sample of patients after stroke, this study aimed to investigate test-retest reliability and repeatability of CPET and to prospectively investigate changes in cardiopulmonary outcomes over a period of four weeks. METHODS: Stroke patients with all degrees of disability underwent 3 separate CPET sessions: 2 tests at baseline (TB1 and TB2) and 1 test at follow up (TF)...
2016: BMC Neurology
David J Goldberg, Benjamin French, Anita L Szwast, Michael G McBride, Stephen M Paridon, Jack Rychik, Laura Mercer-Rosa
OBJECTIVE: Tricuspid annular plane systolic excursion (TAPSE) is a reproducible measure of right ventricular systolic function. We sought to determine the reliability of TAPSE measurements, to evaluate TAPSE in patients with hypoplastic left heart syndrome (HLHS) relative to normal values, and to correlate values of TAPSE with measures of exercise performance. DESIGN: Tricuspid annular plane systolic excursion measurements were performed off-line in the cohort of patients with single right ventricle anatomy who had been enrolled in the Sildenafil After Fontan Operation clinical trial...
September 5, 2016: Echocardiography
Shao-Min Chen, Rong He, Wei-Hong Li, Zhao-Ping Li, Bao-Xia Chen, Xin-Heng Feng
BACKGROUND: Elevated left ventricular filling pressure (LVFP) is an important cause of exercise intolerance in patients with atrial fibrillation (AF). Exercise stress echocardiography could assess LVFP during exercise. The objective of this study was to investigate the relationship between exercise induced elevation of LVFP and exercise capacity in patients with AF. METHODS: This study included 145 consecutive patients (81 men and 64 women; mean age 65.5 ± 8.0 years) with persistent non-valvular AF and normal left ventricular systolic function (left ventricular ejection fraction ≥ 50%)...
September 2016: Journal of Geriatric Cardiology: JGC
Matthew A Wyon, Nick Allen, Ross Cloak, Sarah Beck, Paul Davies, Frances Clarke
An athlete's cardiorespiratory profile, maximal aerobic capacity, and anaerobic threshold is affected by training regimen and competition demands. The present study aimed to ascertain whether there are company rank differences in maximal aerobic capacity and anaerobic threshold in elite classical ballet dancers. Seventy-four volunteers (M 34, F 40) were recruited from two full-time professional classical ballet companies. All participants completed a continuous incremental treadmill protocol with a 1-km/hr speed increase at the end of each 1-min stage until termination criteria had been achieved (e...
September 2016: Medical Problems of Performing Artists
Milena P R Sperling, Rodrigo P Simões, Flávia C R Caruso, Renata G Mendes, Ross Arena, Audrey Borghi-Silva
BACKGROUND: Recent studies have shown that the magnitude of the metabolic and autonomic responses during progressive resistance exercise (PRE) is associated with the determination of the anaerobic threshold (AT). AT is an important parameter to determine intensity in dynamic exercise. OBJECTIVES: To investigate the metabolic and cardiac autonomic responses during dynamic resistance exercise in patients with Coronary Artery Disease (CAD). METHOD: Twenty men (age = 63±7 years) with CAD [Left Ventricular Ejection Fraction (LVEF) = 60±10%] underwent a PRE protocol on a leg press until maximal exertion...
July 2016: Brazilian Journal of Physical Therapy
Alan J Richardson, Rebecca L Relf, Arron Saunders, Oliver R Gibson
Sprint interval training (SIT) is an efficient intervention capable of improving aerobic capacity and exercise performance. This experiment aimed to determine differences in training adaptations and the inflammatory responses following 2 weeks of SIT (30 s maximal work, 4 min recovery; 4-7 repetitions) performed in normoxia or hypoxia. Forty-two untrained participants [(mean ± SD), age 21 ±1 years, body mass 72.1 ±11.4 kg, and height 173 ±10 cm] were equally and randomly assigned to one of three groups; control (CONT; no training, n = 14), normoxic (NORM; SIT in FiO2: 0...
2016: Frontiers in Physiology
Der-Sheng Han, Ming-Yen Hsiao, Tyng-Guey Wang, Ssu-Yuan Chen, Wei-Shiung Yang
BACKGROUND: Patients with spinal cord injury (SCI) have a higher prevalence of cardiovascular diseases compared to the healthy population. Aerobic exercise training is one of the recommended treatments. However, literature regarding the effect of aerobic training on patients with SCI is scarce. This study evaluated changes in parameters of exercise physiology and serum myokines immediately after exercise and after a training program among patients with SCI. METHODS: Male patients with SCI and age- and sex-matched healthy individuals were recruited...
2016: BMC Neurology
Peter Ertl, Annika Kruse, Markus Tilp
The aim of the current paper was to systematically review the relevant existing electromyographic threshold concepts within the literature. The electronic databases MEDLINE and SCOPUS were screened for papers published between January 1980 and April 2015 including the keywords: neuromuscular fatigue threshold, anaerobic threshold, electromyographic threshold, muscular fatigue, aerobic-anaerobictransition, ventilatory threshold, exercise testing, and cycle-ergometer. 32 articles were assessed with regard to their electromyographic methodologies, description of results, statistical analysis and test protocols...
October 2016: Journal of Electromyography and Kinesiology
Mette Holme Jung, Brian Houston, Stuart D Russell, Finn Gustafsson
BACKGROUND: The effect of pump speed increase on sub-maximal exercise tolerance, corresponding to activities of daily living (ADLs), is unknown. The aim of this study was to determine the effects of increasing pump speed during exercise at a sub-maximal level below anaerobic threshold (AT). METHODS: Patients each completed 3 exercise sessions on an ergometer cycle. On Day 1 workload at AT was defined. On Day 2 of the study, 2 sub-maximal tests at a workload below AT were undertaken: one at fixed baseline pump speed (Speed(base)) and the other with baseline pump speed + 800 rpm (Speed(inc))...
July 7, 2016: Journal of Heart and Lung Transplantation
Rodrigo Sudatti Delevatti, Carolina Dertzbocher Feil Pinho, Ana Carolina Kanitz, Cristine Lima Alberton, Elisa Corrêa Marson, Luciana Peruchena Bregagnol, Salime Chedid Lisboa, Beatriz D Schaan, Luiz Fernando Martins Kruel
PURPOSE: To assess the acute glucose responses to the first sessions of three mesocycles of water- and land-based aerobic exercise. METHODS: The water-based exercise group (WBE, n = 14; 54.1 ± 9.1 years) performed deep water walking and/or running, while the land-based exercise group (LBE, n = 11; 60.1 ± 7.3 years) performed walking and/or running on athletic track. In the first mesocycle, patients trained at 85-90% of their anaerobic threshold (AT) for 35 min, progressing to 90-95% of the AT in the second mesocycle, and 95-100% of the AT in the last mesocycle...
August 2016: Complementary Therapies in Clinical Practice
Gianmarco Sainas, Salvatore Melis, Francesco Corona, Andrea Loi, Giovanna Ghiani, Raffaele Milia, Filippo Tocco, Elisabetta Marongiu, Antonio Crisafulli
PURPOSE: The purpose of the present investigation was to study the metabolic demand and cardiovascular response during a typical horse riding session. METHODS: To this aim, 19 (9 male, 10 female) riders, regularly participating in competitions, were enrolled. They underwent a preliminary, incremental exercise test on a cycle-ergometer to assess their anaerobic threshold (AT) and VO2max. Then, participants underwent a riding training session, which comprised periods of walking, trotting, and cantering for a total of 20 min...
October 2016: European Journal of Applied Physiology
Mika L Nonoyama, Susan Marzolini R Kin, Dina Brooks, Paul Oh
OBJECTIVE: To describe the prevalence and impact of respiratory comorbidities on patients undergoing cardiac rehabilitation (CR). METHODS: A retrospective review of a CR database (1999 to 2004) of patients with ischemic heart disease with ≥10 pack per year (ppy) smoking history and respiratory comorbidities (RC), non-respiratory comorbidities (NRC) and no comorbidities (NC) was performed. Primary outcomes at zero, six and 12 months included peak oxygen uptake (VO2peak), maximum workload, resting heart rate, ventilatory anaerobic threshold and anthropometrics...
2016: Canadian Journal of Respiratory Therapy: CJRT
Goncalo V Mendonca, Pedro Pezarat-Correia, João R Vaz, Luís Silva, Kevin S Heffernan
The portion of society aged ≥60 years is the fastest growing population in the Western hemisphere. Aging is associated with numerous changes to systemic physiology that affect physical function and performance. We present a narrative review of the literature aimed at discussing the age-related changes in various metrics of physical performance (exercise economy, anaerobic threshold, peak oxygen uptake, muscle strength, and power). It also explores aging exercise physiology as it relates to global physical performance...
July 26, 2016: Sports Medicine
Kate Hallsworth, Laura Jopson, David E Jones, Michael I Trenell
BACKGROUND: It is being increasingly recognised that reduced cardiorespiratory fitness is associated with poorer outcomes after major surgery. Exercise limitation and reduced aerobic capacity are common in people with end-stage liver disease. There is limited evidence about the role of exercise therapy in the management of primary biliary cirrhosis (PBC) and no studies have looked at the effect of exercise in people with PBC who are awaiting liver transplantation. This case study is the first to report that personalised exercise therapy improves cardiorespiratory fitness in a patient with PBC without worsening symptoms of severe fatigue...
July 2016: Frontline Gastroenterology
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