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"Anaerobic threshold"

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https://www.readbyqxmd.com/read/27930876/pioglitazone-on-improves-whole-body-aerobic-capacity-and-skeletal-muscle-energy-metabolism-in-patients-with-metabolic-syndrome
#1
Takashi Yokota, Shintaro Kinugawa, Kagami Hirabayashi, Tadashi Suga, Shingo Takada, Masashi Omokawa, Tomoyasu Kadoguchi, Masashige Takahashi, Arata Fukushima, Shouji Matsushima, Mayumi Yamato, Koichi Okita, Hiroyuki Tsutsui
AIMS/INTRODUCTION: Low aerobic capacity is a strong and independent predictor of all-cause mortality in patients with metabolic syndrome (MetS). Here, we investigated the effects of pioglitazone treatment on whole-body aerobic capacity and skeletal muscle energy metabolism in MetS patients. MATERIALS AND METHODS: Fourteen male patients with MetS received oral 15 mg/day pioglitazone for 4 months. To assess whole-body aerobic capacity, exercise testing with a bicycle ergometer was performed before and after pioglitazone treatment...
December 8, 2016: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/27871205/the-effects-of-two-different-swimming-training-periodization-on-physiological-parameters-at-various-exercise-intensities
#2
Vicente Javier Clemente-Suárez, Athanasios Dalamitros, João Ribeiro, Ana Sousa, Ricardo J Fernandes, J Paulo Vilas-Boas
This study analysed the effects of two different periodization strategies on physiological parameters at various exercise intensities in competitive swimmers. Seventeen athletes of both sexes were divided to two groups, the traditional periodization (TPG, n = 7) and the reverse periodization group (RPG, n = 10). Each group followed a 10-week training period based on the two different periodization strategies. Before and after training, swimming velocity (SV), energy expenditure (EE), energy cost (EC) and percentage of aerobic (%Aer) and anaerobic (%An) energy contribution to the swimming intensities corresponding to the aerobic threshold (AerT), the anaerobic threshold (AnT) and the velocity at maximal oxygen uptake (vVO2max) were measured...
November 21, 2016: European Journal of Sport Science
https://www.readbyqxmd.com/read/27865723/mechanisms-of-effort-intolerance-in-patients-with-rheumatic-mitral-stenosis-combined-echocardiography-and-cardiopulmonary-stress%C3%A2-protocol
#3
Michal Laufer-Perl, Yaniv Gura, Jason Shimiaie, Jack Sherez, Gregg S Pressman, Galit Aviram, Simon Maltais, Ricki Megidish, Amir Halkin, Meirav Ingbir, Simon Biner, Gad Keren, Yan Topilsky
OBJECTIVES: This study sought to evaluate mechanisms of effort intolerance in patients with rheumatic mitral stenosis (MS). BACKGROUND: Combined stress echocardiography and cardiopulmonary testing allows assessment of cardiac function, hemodynamics, and oxygen extraction (A-Vo2 difference). METHODS: Using semirecumbent bicycle exercise, 20 patients with rheumatic MS (valve area 1.36 ± 0.4 cm(2)) were compared to 20 control subjects at 4 pre-defined activity stages (rest, unloaded, anaerobic threshold, and peak)...
November 10, 2016: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/27856303/effects-of-tibetan-turnip-brassica-rapa-l-on-promoting-hypoxia-tolerance-in-healthy-humans
#4
Bingquan Chu, Chun Chen, Jiaojie Li, Xiaojian Chen, Yunhong Li, Weimin Tang, Lu Jin, Ying Zhang
ETHNOPHARMACOLOGICAL RELEVANCE: Tibetan turnip (Brassica rapa L.), widely distributed in Tibet region, is an edible and medical plant with effects of "tonic and anti-hypoxia" "heat-clearing and detoxification" and "alleviating fatigue" according to traditional Tibetan medical books. AIM OF THE STUDY: This research systematically studied the effects of Tibetan turnip on promoting hypoxia-tolerance in humans and the mechanisms. MATERIALS AND METHODS: A 7-day, self-control and single-blind human feeding trial was conducted among 27 healthy subjects with 8 males and 10 females in feeding group fed with 7...
November 14, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27848017/effects-of-a-12-week-short-interval-intermittent-low-intensity-slow-jogging-program-on-skeletal-muscle-fat-infiltration-and-fitness-in-older-adults-randomized-controlled-trial
#5
Masahiro Ikenaga, Yosuke Yamada, Yujiro Kose, Kazuhiro Morimura, Yasuki Higaki, Akira Kiyonaga, Hiroaki Tanaka
PURPOSE: We developed a short-interval, low-intensity, slow-jogging (SJ) program consisting of sets of 1 min of SJ at walking speed and 1 min of walking. We aimed to examine the effects of an easily performed SJ program on skeletal muscle, fat infiltration, and fitness in older adults. METHODS: A total of 81 community-dwelling, independent, older adults (70.8 ± 4.0 years) were randomly assigned to the SJ or control group. The SJ group participants were encouraged to perform 90 min of SJ at their anaerobic threshold (AT) intensity and 90 min of walking intermittently per week...
November 15, 2016: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/27832671/exercise-based-cardiac-rehabilitation-in-coronary-disease-training-impulse-or-modalities
#6
P-M Leprêtre, M Ghannem, M Bulvestre, S Ahmaidi, S Delanaud, T Weissland, P Lopes
To compare the effects of 2 short programs with similar training load (TL), based on combined aerobic - resistance training (CT) or aerobic training (AT) on cardiorespiratory responses, 32 patients with coronary heart disease (CHD: 63.8±8.0y, 1.73±0.06 m, 84.8±15.9 kg, Left Ventricular Ejection Fraction: 0.53±0.8) performed 4 weeks of exercise rehabilitation based on CT (n=16) or AT (n=16). Maximal tolerated power (MTP), peak values of oxygen uptake (VO2peak) and heart rate (HRpeak), anaerobic threshold (VT1) were determined during an incremental cycling exercise test before and after training periods...
November 10, 2016: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/27810297/small-unrepaired-ventricular-septal-defects-reveal-poor-exercise-capacity-compared-with-healthy-peers-a-prospective-cohort-study
#7
Marie Maagaard, Johan Heiberg, Vibeke E Hjortdal
BACKGROUND: Small ventricular septal defects (VSDs) are considered to be without hemodynamic influence and most remain unrepaired. However, studies recently described late cardiac adverse consequences that could potentially affect functional capacity. Yet, this has never been assessed in adulthood. Therefore, the aim was to determine peak exercise capacity in adults with small VSDs compared with healthy, matched controls. METHODS: In a prospective, cohort study we included patients with unrepaired VSDs and healthy controls, (age 18 to 40years)...
October 29, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27765184/effect-of-aldosterone-antagonism-on%C3%A2-exercise-tolerance-in-heart-failure-with%C3%A2-preserved-ejection-fraction
#8
Wojciech Kosmala, Aleksandra Rojek, Monika Przewlocka-Kosmala, Leah Wright, Andrzej Mysiak, Thomas H Marwick
BACKGROUND: Impaired functional capacity is a hallmark of patients with heart failure with preserved ejection fraction (HFpEF). Despite the association of HFpEF with reduced myocardial compliance attributed to fibrosis, spironolactone has not been shown to alter outcomes-perhaps reflecting the heterogeneity of underlying pathological mechanisms. OBJECTIVES: The authors sought to identify improvement in exercise capacity with spironolactone in the subset of patients with HFpEF with exercise-induced increase in ratio between early mitral inflow velocity and mitral annular early diastolic velocity (E/e') reflecting elevation of left ventricular (LV) filling pressure...
October 25, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27747790/fat-utilization-during-high-intensity-exercise-when-does-it-end
#9
Ratko Peric, Marco Meucci, Zoran Nikolovski
BACKGROUND: This study examined substrate oxidation at high-intensity exercise and aimed to determine when fat oxidation ends (FATmin). We hypothesized the existence of a connection between the anaerobic threshold (AnT) and FATmin point. METHODS: Breath-by-breath data obtained from indirect calorimetry during a graded treadmill test were used to measure substrate oxidation and maximal oxygen uptake (VO2max) on 47 males (30 athletes (ATL) and 17 non-athletes (NATL))...
December 2016: Sports Medicine—Open
https://www.readbyqxmd.com/read/27742182/discriminating-circulatory-problems-from-deconditioning-echocardiogram-and-cardio-pulmonary-exercise-test-analysis
#10
Zach Rozenbaum, Shafik Khoury, Galit Aviram, Yaniv Gura, Jack Sherez, Avi Man, Jason Shimiaie, Thierry Le Tourneau, Amir Halkin, Simon Biner, Gad Keren, Yan Topilsky
BACKGROUND: Discriminating circulatory problems with reduced stroke volume from de-conditioning in which the muscles cannot consume O2 normally by gas exchange parameters is difficult. METHODS: We performed combined stress echo and cardio-pulmonary (CPET) tests in 110 patients (20 normal effort capacity, 54 attenuated stroke volume response, 36 de-conditioning) to evaluate multiple hemodynamic parameters and oxygen content difference (A-VO2 Difference) in four predefined activity levels to assess which of the gas measures may help in the discrimination...
October 11, 2016: Chest
https://www.readbyqxmd.com/read/27721367/a-pair-of-identical-twins-discordant-for-myalgic-encephalomyelitis-chronic-fatigue-syndrome-differ-in-physiological-parameters-and-gut-microbiome-composition
#11
Ludovic Giloteaux, Maureen R Hanson, Betsy A Keller
BACKGROUND Patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) present with profound fatigue, flu-like symptoms, pain, cognitive impairment, orthostatic intolerance, and post-exertional malaise (PEM), and exacerbation of some or all of the baseline symptoms. CASE REPORT We report on a pair of 34-year-old monozygotic twins discordant for ME/CFS, with WELL, the non-affected twin, and ILL, the affected twin. Both twins performed a two-day cardiopulmonary exercise test (CPET), pre- and post-exercise blood samples were drawn, and both provided stool samples for biochemical and molecular analysis...
October 10, 2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/27676142/post-exercise-neurovascular-control-in-chronic-heart-failure-patients
#12
T S Nobre, R V Groehs, L F Azevedo, L M Antunes-Correa, D G Martinez, M J N N Alves, C E Negrao
It remains unknown whether or not a reduction in muscle sympathetic nerve activity in heart failure patients is associated over time with the effects of long- or short-term repeated exercise. 10 chronic heart failure patients, age 49±3 years old, functional class I-III NYHA, ejection fraction <40% were randomly submitted to either an acute bout of moderate continuous exercise OR high-intensity interval exercise. Muscle sympathetic nerve activity (microneurography) and forearm blood flow (venous occlusion plethysmography) were evaluated pre- and post-exercise sessions...
December 2016: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/27664807/endothelial-function-and-arterial-stiffness-relate-to-functional-outcomes-in-adolescent-and-young-adult-fontan-survivors
#13
Bryan H Goldstein, Elaine M Urbina, Philip R Khoury, Zhiqian Gao, Michelle A Amos, Wayne A Mays, Andrew N Redington, Bradley S Marino
BACKGROUND: Fontan survivors demonstrate diminished vascular function and functional outcomes, but the relationships between these measures have not been established. METHODS AND RESULTS: We performed a cross-sectional study of 60 Fontan survivors (52% male) with a mean age of 13.9±4.1 years and mean Fontan duration of 9.9±4.2 years. Multimodality assessment of endothelial function (reactive hyperemia index and flow-mediated dilation) and arterial stiffness (augmentation index and baseline pulse amplitude) was performed with peripheral arterial tonometry and brachial flow-mediated dilation...
September 24, 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27600918/test-retest-reliability-and-four-week-changes-in-cardiopulmonary-fitness-in-stroke-patients-evaluation-using-a-robotics-assisted-tilt-table
#14
Jittima Saengsuwan, Lucia Berger, Corina Schuster-Amft, Tobias Nef, Kenneth J Hunt
BACKGROUND: Exercise testing devices for evaluating cardiopulmonary fitness in patients with severe disability after stroke are lacking, but we have adapted a robotics-assisted tilt table (RATT) for cardiopulmonary exercise testing (CPET). Using the RATT in a sample of patients after stroke, this study aimed to investigate test-retest reliability and repeatability of CPET and to prospectively investigate changes in cardiopulmonary outcomes over a period of four weeks. METHODS: Stroke patients with all degrees of disability underwent 3 separate CPET sessions: 2 tests at baseline (TB1 and TB2) and 1 test at follow up (TF)...
September 6, 2016: BMC Neurology
https://www.readbyqxmd.com/read/27596010/tricuspid-annular-plane-systolic-excursion-correlates-with-exercise-capacity-in-a-cohort-of-patients-with-hypoplastic-left-heart-syndrome-after-fontan-operation
#15
David J Goldberg, Benjamin French, Anita L Szwast, Michael G McBride, Stephen M Paridon, Jack Rychik, Laura Mercer-Rosa
OBJECTIVE: Tricuspid annular plane systolic excursion (TAPSE) is a reproducible measure of right ventricular systolic function. We sought to determine the reliability of TAPSE measurements, to evaluate TAPSE in patients with hypoplastic left heart syndrome (HLHS) relative to normal values, and to correlate values of TAPSE with measures of exercise performance. DESIGN: Tricuspid annular plane systolic excursion measurements were performed off-line in the cohort of patients with single right ventricle anatomy who had been enrolled in the Sildenafil After Fontan Operation clinical trial...
December 2016: Echocardiography
https://www.readbyqxmd.com/read/27582773/relationship-between-exercise-induced-elevation-of-left-ventricular-filling-pressure-and-exercise-intolerance-in-patients-with-atrial-fibrillation
#16
Shao-Min Chen, Rong He, Wei-Hong Li, Zhao-Ping Li, Bao-Xia Chen, Xin-Heng Feng
BACKGROUND: Elevated left ventricular filling pressure (LVFP) is an important cause of exercise intolerance in patients with atrial fibrillation (AF). Exercise stress echocardiography could assess LVFP during exercise. The objective of this study was to investigate the relationship between exercise induced elevation of LVFP and exercise capacity in patients with AF. METHODS: This study included 145 consecutive patients (81 men and 64 women; mean age 65.5 ± 8.0 years) with persistent non-valvular AF and normal left ventricular systolic function (left ventricular ejection fraction ≥ 50%)...
September 2016: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/27575290/assessment-of-maximum-aerobic-capacity-and-anaerobic-threshold-of-elite-ballet-dancers
#17
Matthew A Wyon, Nick Allen, Ross Cloak, Sarah Beck, Paul Davies, Frances Clarke
An athlete's cardiorespiratory profile, maximal aerobic capacity, and anaerobic threshold is affected by training regimen and competition demands. The present study aimed to ascertain whether there are company rank differences in maximal aerobic capacity and anaerobic threshold in elite classical ballet dancers. Seventy-four volunteers (M 34, F 40) were recruited from two full-time professional classical ballet companies. All participants completed a continuous incremental treadmill protocol with a 1-km/hr speed increase at the end of each 1-min stage until termination criteria had been achieved (e...
September 2016: Medical Problems of Performing Artists
https://www.readbyqxmd.com/read/27556384/is-heart-rate-variability-a-feasible-method-to-determine-anaerobic-threshold-in-progressive-resistance-exercise-in-coronary-artery-disease
#18
Milena P R Sperling, Rodrigo P Simões, Flávia C R Caruso, Renata G Mendes, Ross Arena, Audrey Borghi-Silva
BACKGROUND: Recent studies have shown that the magnitude of the metabolic and autonomic responses during progressive resistance exercise (PRE) is associated with the determination of the anaerobic threshold (AT). AT is an important parameter to determine intensity in dynamic exercise. OBJECTIVES: To investigate the metabolic and cardiac autonomic responses during dynamic resistance exercise in patients with Coronary Artery Disease (CAD). METHOD: Twenty men (age = 63±7 years) with CAD [Left Ventricular Ejection Fraction (LVEF) = 60±10%] underwent a PRE protocol on a leg press until maximal exertion...
July 2016: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/27536249/similar-inflammatory-responses-following-sprint-interval-training-performed-in-hypoxia-and-normoxia
#19
Alan J Richardson, Rebecca L Relf, Arron Saunders, Oliver R Gibson
Sprint interval training (SIT) is an efficient intervention capable of improving aerobic capacity and exercise performance. This experiment aimed to determine differences in training adaptations and the inflammatory responses following 2 weeks of SIT (30 s maximal work, 4 min recovery; 4-7 repetitions) performed in normoxia or hypoxia. Forty-two untrained participants [(mean ± SD), age 21 ±1 years, body mass 72.1 ±11.4 kg, and height 173 ±10 cm] were equally and randomly assigned to one of three groups; control (CONT; no training, n = 14), normoxic (NORM; SIT in FiO2: 0...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27534935/association-of-serum-myokines-and-aerobic-exercise-training-in-patients-with-spinal-cord-injury-an-observational-study
#20
Der-Sheng Han, Ming-Yen Hsiao, Tyng-Guey Wang, Ssu-Yuan Chen, Wei-Shiung Yang
BACKGROUND: Patients with spinal cord injury (SCI) have a higher prevalence of cardiovascular diseases compared to the healthy population. Aerobic exercise training is one of the recommended treatments. However, literature regarding the effect of aerobic training on patients with SCI is scarce. This study evaluated changes in parameters of exercise physiology and serum myokines immediately after exercise and after a training program among patients with SCI. METHODS: Male patients with SCI and age- and sex-matched healthy individuals were recruited...
August 17, 2016: BMC Neurology
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