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https://www.readbyqxmd.com/read/29243490/percutaneous-cryoablation-of-breast-tumors-in-patients-with-stable-metastatic-breast-cancer-safety-feasibility-and-efficacy
#1
Beji H, Pilleul F, Picard R, Tredan O, Bouhamama A, Peix M, Mavrovi E, Mastier C
PURPOSE: To evaluate safety, feasibility, and efficacy of percutaneous cryoablation of breast tumors in patients with clinically stable metastatic breast cancer, and to compare the findings with reports on alternative procedures, namely surgery and local radiotherapy. METHODS: Seventeen female patients (average age of 54.8 years +/- 10.8 ; range 37-72) with primary breast tumor not surgically treated because of metastatic disease were included. Patients were treated for their primary lesion by percutaneous cryotherapy in period of stable disease...
December 15, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29241704/development-and-characterization-of-an-anthropomorphic-breast-phantom-for-permanent-breast-seed-implant-brachytherapy-credentialing
#2
Michael Roumeliotis, Sarah Quirk, Matthew Skarsgard, Tiana Trumpour, Elizabeth Watt, Tyler Meyer
PURPOSE: To develop an anthropomorphic breast phantom for use in credentialing of permanent breast seed implant brachytherapy. METHODS AND MATERIALS: A representative external contour and target volume was used as the basis of mold manufacturing for anthropomorphic breast phantom development. Both target and normal tissue were composed of gel-like materials that provide suitable computed tomography and ultrasound contrast for brachytherapy delivery. The phantoms were evaluated for consistency in construction (target location) and Hounsfield unit (computed tomography contrast)...
December 11, 2017: Brachytherapy
https://www.readbyqxmd.com/read/29241077/pectoral-nerve-blocks-to-improve-analgesia-after-breast-cancer-surgery-a-prospective-randomized-and-controlled-trial
#3
Neethu M, Ravinder Kumar Pandey, Ankur Sharma, Vanlalnghaka Darlong, Jyotsna Punj, Renu Sinha, Preet Mohinder Singh, Nandini Hamshi, Rakesh Garg, Chandralekha Chandralekha, Anurag Srivastava
STUDY OBJECTIVE: To evaluate the analgesic efficacy of ultrasound guided combined pectoral nerve blocks I and II in patients scheduled for surgery for breast cancer. DESIGN: Prospective, randomized, control trial. SETTING: Operating rooms in a tertiary care hospital of Northern India. PATIENTS: Sixty American Society of Anesthesiologists status I to II adult women, aged 18-70years were enrolled in this study. INTERVENTIONS: Patients were randomized into two groups (30 patients in each group), PECS (P) group and control (C) group...
December 11, 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/29240317/inflammations-of-the-mammary-gland
#4
Tuomo Meretoja, Hanna Ihalainen, Marjut Leidenius
Breast inflammation, i.e. mastitis is an entity with a variable etiology and severity, typically affecting women of fertile age. In most cases, anamnesis reveals the etiology of the disease, bacterial puerperal mastitis associated with breastfeeding being the most common. Periductal mastitis is a breast inflammation typically associated with smoking in women of 40 to 50 years of age, localized to the region of the areola. Granulomatous mastitis and other rare breast inflammations usually require specialized care...
2017: Duodecim; Lääketieteellinen Aikakauskirja
https://www.readbyqxmd.com/read/29238749/a-feasibility-study-of-neoadjuvant-talazoparib-for-operable-breast-cancer-patients-with-a-germline-brca-mutation-demonstrates-marked-activity
#5
J K Litton, M Scoggins, D L Ramirez, R K Murthy, G J Whitman, K R Hess, B E Adrada, S L Moulder, C H Barcenas, V Valero, J Schwartz Gomez, E A Mittendorf, A Thompson, T Helgason, G B Mills, H Piwnica-Worms, B K Arun
This study was undertaken to determine the feasibility of enrolling breast cancer patients on a single-agent-targeted therapy trial before neoadjuvant chemotherapy. Specifically, we evaluated talazoparib in patients harboring a deleterious BRCA mutation (BRCA+). Patients with a germline BRCA mutation and ≥1 cm, HER2-negative primary tumors were eligible. Study participants underwent a pretreatment biopsy, 2 months of talazoparib, off-study core biopsy, anthracycline, and taxane-based chemotherapy ± carboplatin, followed by surgery...
2017: NPJ Breast Cancer
https://www.readbyqxmd.com/read/29238489/comparison-of-mammography-and-ultrasonography-findings-with-pathology-results-in-patients-with-breast-cancer-in-birjand-iran
#6
Fatemeh Haghighi, Ghodratollah Naseh, Mahyar Mohammadifard, Naeeme Abdollahi
Background: Early diagnosis of breast cancer, the incidence of which among Iranian women is about a decade earlier than in developed countries, is important. Objective: To compare mammography and ultrasonography findings with those of pathology in patients with breast cancer. Methods: This descriptive cross-sectional study was performed using medical records of 79 patients with breast malignancies, who were referred to Imam Reza Hospital and private laboratories of Birjand, Iran, from December 2012 to December 2014...
October 2017: Electronic Physician
https://www.readbyqxmd.com/read/29231050/follow-up-interval-for-probably-benign-breast-lesions-on-screening-ultrasound-in-women-at-average-risk-for-breast-cancer-with-dense-breasts
#7
Hee Jung Moon, Min Jung Kim, Jung Hyun Yoon, Eun-Kyung Kim
Background Women at high risk for breast cancer and women at average risk have different pretest probabilities. Probably benign lesions on screening ultrasound (US) should be assessed and managed differently for these two risk groups. Purpose To evaluate the effectiveness of short-term follow-up for probably benign lesions on screening US in women at average risk for breast cancer with dense breasts. Material and Methods A total of 445 women at average risk for breast cancer with probably benign lesions on screening US, dense breasts, and negative or benign mammography results were included...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/29230131/body-art-confounding-a-case-of-breast-cancer
#8
Lena Gowharji, Dana Smetherman, Brett Roberts
Background: Heavy metals in tattoo ink can be deposited in axillary lymph nodes, mimicking malignant calcifications. High-density foci in axillary lymph nodes can be the sequelae of a benign or malignant process. Case Report: A 34-year-old female presented with left breast discomfort. Mammography showed suspicious left breast calcifications for which biopsy revealed multicentric ductal carcinoma in situ. Imaging also showed high-density foci in her left axillary lymph nodes suspicious for nodal metastases; however, biopsy of the lymph nodes found the high-density foci to be pigment-laden histiocytes from tattoo ink metallic deposits...
2017: Ochsner Journal
https://www.readbyqxmd.com/read/29227816/the-use-of-breast-imaging-for-predicting-response-to%C3%A2-neoadjuvant-lapatinib-trastuzumab-and-their-combination-in-her2-positive-breast-cancer-results%C3%A2-from-neo-altto
#9
S Di Cosimo, C Campbell, H A Azim, G Galli, G Bregni, G Curigliano, C Criscitiello, M Izquierdo, L de la Pena, D Fumagalli, L Fein, J Vinholes, W M J Ng, M Colleoni, A Ferro, B J Naume, A Patel, J Huober, M J Piccart-Gebhart, J Baselga, E de Azambuja
AIM: To determine the value of mammography and breast ultrasound (US) in predicting outcomes in HER2 positive breast cancer patients (pts) within Neo-ALTTO trial. PATIENTS AND METHODS: Mammography and US were required at baseline, week 6 and surgery. Two independent blinded investigators reviewed the measurements and assigned the corresponding response category. Pts showing complete or partial response according to RECIST (v1.1) were classified as responders. The association between imaging response at week 6 or prior to surgery was evaluated with respect to pathological complete response (pCR) and event-free Survival (EFS)...
December 8, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/29224890/advances-in-breast-intervention-where-are-we-now-and-where-should-we-be
#10
REVIEW
W B G Sanderink, R M Mann
In the past four decades, a variety of methods for minimal or non-invasive diagnosis and treatment of breast cancer have been introduced. Although breast imaging has become more and more specific for diagnosis, specimen biopsy with histopathological confirmation is still necessary. Core-needle biopsy under ultrasound guidance is the appropriate first choice for the diagnosis of most lesions. Fine-needle aspiration is of interest for identification of the presence of metastatic disease in abnormal lymph nodes...
December 7, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/29222002/impact-of-simulation-based-training-on%C3%A2-radiology-trainee-education-in-ultrasound-guided-breast-biopsies
#11
Ashley A Roark, Lilian O Ebuoma, Tamara Ortiz-Perez, Karla A Sepulveda, Frederick J Severs, Tao Wang, Ana Paula Benveniste, Emily L Sedgwick
PURPOSE: The aim of this study is to determine the impact of a simulation-based ultrasound-guided (USG) breast biopsy training session on radiology trainee procedural knowledge, comfort levels, and overall procedural confidence and anxiety. METHODS: Twenty-one diagnostic radiology residents from a single academic institution were recruited to participate in an USG breast biopsy training session. The residents filled out a questionnaire before and after the training session...
December 5, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29220208/changing-utilization-of-noninvasive-diagnostic-imaging-over-2-decades-an-examination-family-focused-analysis-of-medicare-claims-using-the-neiman-imaging-types-of-service-categorization-system
#12
David A Rosman, Richard Duszak, Wenyi Wang, Danny R Hughes, Andrew B Rosenkrantz
OBJECTIVE: The objective of our study was to use a new modality and body region categorization system to assess changing utilization of noninvasive diagnostic imaging in the Medicare fee-for-service population over a recent 20-year period (1994-2013). MATERIALS AND METHODS: All Medicare Part B Physician Fee Schedule services billed between 1994 and 2013 were identified using Physician/Supplier Procedure Summary master files. Billed codes for diagnostic imaging were classified using the Neiman Imaging Types of Service (NITOS) coding system by both modality and body region...
December 8, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29215311/classification-of-breast-cancer-from-ultrasound-imaging-using-a-generic-deep-learning-analysis-software-a-pilot-study
#13
Anton S Becker, Michael Mueller, Elina Stoffel, Magda Marcon, Soleen Ghafoor, Andreas Boss
PURPOSE: To train a generic deep learning software (DLS) to classify breast cancer on ultrasound images and to compare its performance to human readers with variable breast imaging experience. METHODS: In this IRB-approved, HIPAA compliant, retrospective study, all breast ultrasound examinations from January 1, 2014, to December 31, 2014 were reviewed. Patients with postsurgical scars, initially indeterminate, or malignant lesions with histological diagnoses or 2-year follow-up were included...
December 7, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29209873/99mtc-rituximab-as-a-tracer-for-sentinel-lymph-node-biopsy-in-breast-cancer-patients-a-single-center-analysis
#14
Jiwei Wang, Tie Fan, Yingjian He, Xue Chen, Zhaoqing Fan, Yuntao Xie, Tianfeng Wang, Jinfeng Li, Tao Ouyang
PURPOSE: This study aimed to determine the long-term prognosis of breast cancer patients with 99mTc-rituximab for sentinel lymph node biopsy (SLNB). METHODS: A total of 2947 patients with negative sentinel lymph nodes (SLNs) omitting axillary lymph node dissection (ALND), treated between June 2005 and December 2013, were retrospectively analyzed. SLNB was performed prior to adjuvant therapy. RESULTS: After a median follow-up of 62 months, 22 cases of axillary recurrence (AR) were observed...
December 6, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29209825/performance-of-4%C3%A2-years-of-population-based-mammography-screening-for-breast-cancer-combined-with-ultrasound-in-tyrol-austria
#15
Sabine Geiger-Gritsch, Martin Daniaux, Wolfgang Buchberger, Rudolf Knapp, Willi Oberaigner
BACKGROUND: Systems for the delivery of screening mammography vary among countries and these differences can influence screening effectiveness. We evaluated the performance of organized mammography screening for breast cancer combined with ultrasound in Tyrol / Austria, an approach that differs from many other population-based screening programs. METHODS: Data on women aged 40-69 years screened in the period from June 2008 to May 2012 were collected within the framework of an organized screening program...
December 5, 2017: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/29208778/comparison-of-the-ultrasound-guided-tru-cut-biopsy-with-postoperative-histopathology-results-in-patients-with-breast-mass
#16
Mehmet Emin Gunes
AIM: We aimed to compare the tru-cut biopsy and postoperative pathology results of breast lesions with suspicion of malignancy. Furthermore we aimed to determine the efficacy, specificity and sensitivity of the tru-cut biopsy. METHODOLOGY: 140 patients who were operated due to breast mass following tru-cut biopsy were retrospectively evalu-ated. Patients' demographic characteristics, imaging findings, biopsy and histopathology results were compared. RESULTS: The mean age of 140 patients was 51...
November 29, 2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/29207805/benign-lesions-on-screening-mammography-increasing-diagnostic-confidence-in-a-hitherto-unscreened-population
#17
Piyush Joshi, Rohit Sharma
Introduction: Screening mammography is used for detection of breast cancer and is interpreted using the Breast Image Reporting and Data System (BIRADS) convention. It is not routinely offered to women in countries which do not have a national screening programme resulting in a challenge for the radiologist who has to interpret these in the absence of previous mammograms. Aim: To analyse benign and probably benign lesions in screening mammograms in a hitherto unscreened population and suggest protocols to increase diagnostic confidence...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29205451/subdermal-ultrasound-contrast-agent-injection-for-sentinel-lymph-node-identification-an-analysis-of-safety-and-contrast-agent-dose-in-healthy-volunteers
#18
Priscilla Machado, Maria Stanczak, Ji-Bin Liu, Jason N Moore, John R Eisenbrey, Laurence Needleman, Walter K Kraft, Flemming Forsberg
OBJECTIVES: Mapping of the lymphatic chain for identification of the sentinel lymph node (SLN) is an important aspect of predicting outcomes for patients with breast cancer, and it is usually performed as an intraoperative procedure using blue dye and/or radiopharmaceutical agents. Recently, the use of contrast-enhanced ultrasound (CEUS) has been proposed as an alternative imaging technique for this mapping. The objective of this study was to evaluate the use of subdermal administration of the ultrasound (US) contrast agent Sonazoid (GE Healthcare, Oslo, Norway) in terms of patient safety and to select the dose to be used for lymphatic applications in humans...
December 5, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29205174/numerical-implementation-of-magneto-acousto-electric-tomography-maet-using-a-linear-phased-array-transducer
#19
Mehmet Soner Gözü, Reyhan Zengin, Nevzat Guneri Gencer
In this study, the performance and implementation of magneto-acousto-electric tomography (MAET) is investigated using a linear phased array (LPA) transducer. The goal of MAET is to image the conductivity distribution in biological bodies. It uses the interaction between ultrasound and a static magnetic field to generate velocity current density distribution inside the body. The resultant voltage due to velocity current density is sensed by surface electrodes attached on the body. In this study, the theory of MAET is reviewed...
December 5, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29205144/primitive-squamous-cell-carcinoma-of-the-breast-sccb-case-report-of-an-uncommon-variant-of-metaplastic-carcinoma
#20
C Punzo, F Fortarezza, V De Ruvo, M Minafra, R Laforgia, G Casamassina, F Pezzuto, A Punzi, C Caporusso, G Angelelli, N Palasciano
INTRODUCTION: Metaplastic carcinoma of the breast includes a heterogeneous group of neoplasms characterized by admixture of adenocarcinoma with area of squamous, chondroid and osseous differentiation. If the tumor shows pure squamous differentiation, it is designated as squamous carcinoma. SCCB accounts for less than 1% of all invasive breast carcinoma. It can present as cystic lesions and simulate a breast abscess. CASE REPORT: A 75-year old woman was visited at our General Surgery Unit for a palpable lump, about 5 cm in size, at the lower inner quadrant of right breast...
May 2017: Il Giornale di Chirurgia
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