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https://www.readbyqxmd.com/read/29924021/mammographic-and-ultrasound-findings-in-poroid-hidradenoma-of-the-breast-mimicking-intraductal-papilloma-and-papillary-carcinoma-a-case-report
#1
Bo Hwa Choi, Mi Young Kim, So Dug Lim, Jung-Hyun Yang, Ji Young Ha, Nami Choi
RATIONALE: Poroid hidradenoma (PH) is a rare variant of benign sweat gland neoplasm without connection to the epidermis. This tumor presents clinically as a solitary lesion with a cystic component located in the subcutaneous layer abutting the skin. On ultrasound, it appears as a circumscribed complex cystic and solid mass abutting the dermis. The occurrence of PH in the breast is very rare. Its features overlap with intraductal papilloma and papillary carcinoma. PATIENT CONCERNS: A 66-year-old woman presented with a palpable lump in her right breast...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29923998/clinical-study-on-postoperative-triple-negative-breast-cancer-with-chinese-medicine-study-protocol-for-an-observational-cohort-trial
#2
Jiajing Chen, Yuenong Qin, Chenping Sun, Wei Hao, Shuai Zhang, Yi Wang, Juan Chen, Lixin Chen, Yiying Ruan, Sheng Liu
BACKGROUND: Breast cancer (BC) poses a tremendous threat to the health of women worldwide, especially triple-negative breast cancers (TNBCs). Currently, the curative effect of traditional Chinese medicine (TCM) has been recognized in more and more people worldwide; however, the specific effect has not been systematically evaluated. The purpose of this cohort study is to evaluate the clinical effects of TCM syndrome differentiation on recurrence and metastasis rate, survival rate, and the quality of life in patients with TNBC...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29923514/whole-body-18-f-fluorodeoxyglucose-positron-emission-tomography-computed-tomography-18-f-fdg-pet-ct-for-staging-locally-advanced-breast-cancer-a-prospective-study-from-a-tertiary-cancer-centre-in-south-india
#3
Sivanath Reddy Gajjala, Narendra Hulikal, Silpa Kadiyala, Radhika Kottu, Tekchand Kalawat
Background & objectives: Locally advanced breast cancer (LABC) is associated with substantial risk of occult metastases. The patients with LABC have high rate of systemic relapse, suggesting inadequacy of the current conventional staging in detecting the occult metastatic spread. 18 F-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET/CT) is a new modality in the staging of breast cancer patients. Hence, this study was conducted to evaluate the role of 18 F-FDG PET/CT in initial staging of LABC and to compare it with conventional methods...
March 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29921747/diagnostic-performance-of-contrast-enhanced-ultrasound-and-enhanced-magnetic-resonance-for-breast-nodules
#4
Cui-Ying Li, Hai-Yan Gong, Li-Jun Ling, Li-Wen Du, Tong Su, Shui Wang, Jie Wang
In the current study, we sought to evaluate the diagnostic efficacies of conventional ultrasound (US), contrast-enhanced US (CEUS), combined US and CEUS and magnetic resonance imaging (MRI) in detecting focal solid breast lesions. Totally 117 patients with 120 BI-RADS category 4A-5 breast lesions were evaluated by conventional US and CEUS, and MRI, respectively. SonoVue was used as contrast agent in CEUS and injected as an intravenous bolus; nodule scan was performed 4 minutes after bolus injection. A specific sonographic quantification software was used to obtain color-coded maps of perfusion parameters for the investigated lesion, namely the time-intensity curve...
June 1, 2018: Journal of Biomedical Research
https://www.readbyqxmd.com/read/29917175/-breast-implant-associated-anaplastic-large-cell-lymphoma-bia-alcl
#5
Per Hedén, Birgit Stark
Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a distinct type of T-cell lymphoma, developing around implants, that can occur 2 to 25 years (median 8 years) post-implantation. Most patients present with a swelling of the breast, which is usually associated with pain and fluid collecting around the implant. Less commonly, a lump in the breast and/or in the axilla can be present. A periprosthetic fluid collection (> 1 year post-implantation) should be investigated with ultrasound and fine needle aspiration...
June 12, 2018: Läkartidningen
https://www.readbyqxmd.com/read/29916500/pa-us-dual-modality-imaging-to-guide-vegfr-2-targeted-photothermal-therapy-using-znpc-pfh-loaded-polymeric-nanoparticles
#6
Yu-Li Chen, Feng-Qiu Liu, Yuan Guo, Juan Cheng, Lu Yang, Min Lu, Pan Li, Jie Xu, Tao Yu, Zhi-Gang Wang, Yang Cao, Hai-Tao Ran
Angiogenesis is a common pathological characteristic of many solid tumors and vulnerable atherosclerotic plaques. Photothermal therapy (PTT) is a promising method to reduce neovascularization. To increase the targeting ability and efficiency of PTT, a novel polymeric nanosystem that encapsulates phthalocyanine zinc (ZnPc) and perfluorohexane (PFH) was developed to target the new blood vessels of breast tumors. After being conjugated to the anti-VEGFR-2 antibody, the polymeric nanoparticles (NPs) targeted vascular endothelial cells efficiently...
June 19, 2018: Biomaterials Science
https://www.readbyqxmd.com/read/29907750/examining-the-associations-among-fibrocystic-breast-change-total-lean-mass-and-percent-body-fat
#7
Yuan-Yuei Chen, Wen-Hui Fang, Chung-Ching Wang, Tung-Wei Kao, Yaw-Wen Chang, Hui-Fang Yang, Chen-Jung Wu, Yu-Shan Sun, Wei-Liang Chen
Fibrocystic breast change (FBC) is extremely common and occurrs in 90% of women during their lives. The association between body composition and risk of breast cancer is well established. We hypothesized that the effect might exist during the development of FBC. Our aim was to examine the relationships of total lean mass (TLM) and percent body fat (PBF) with FBC in a general female population. In total, 8477 female subjects aged 20 years or older were enrolled in the study at the Tri-Service General Hospital in Taiwan from 2011 to 2016...
June 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29907260/usefulness-of-the-twinkling-artifact-on-doppler-ultrasound-for-the-detection-of-breast-microcalcifications
#8
A Relea, J A Alonso, M González, C Zornoza, S Bahamonde, B E Viñuela, M B Encinas
OBJECTIVE: To determine whether the twinkling artifact on Doppler ultrasound imaging corresponds to microcalcifications previously seen on mammograms and to evaluate the usefulness of this finding in the ultrasound management of suspicious microcalcifications. MATERIAL AND METHODS: We used ultrasonography to prospectively examine 46 consecutive patients with groups of microcalcifications suspicious for malignancy identified at mammography, searching for the presence of the twinkling artifact to identify the microcalcifications...
June 12, 2018: Radiología
https://www.readbyqxmd.com/read/29907218/pediatric-breast-masses-an-argument-for-observation
#9
Cory M McLaughlin, Jessica Gonzalez-Hernandez, Monica Bennett, Hannah G Piper
BACKGROUND: Pediatric breast masses can be a diagnostic challenge. Nearly all are benign, but there is no consensus on which should be removed. We hypothesized that children with asymptomatic breast lesions can be safely managed nonoperatively. METHODS: We performed a single-institution retrospective review of children (≤18 y) who underwent breast mass excision from 2008 to 2016. Male patients with gynecomastia and those who had needle biopsy without formal excision were excluded...
August 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29905036/feasibility-of-using-negative-ultrasonography-results-of-axillary-lymph-nodes-to-predict-sentinel-lymph-node-metastasis-in-breast-cancer-patients
#10
Xue Chen, Yingjian He, Jiwei Wang, Ling Huo, Zhaoqing Fan, Jinfeng Li, Yuntao Xie, Tianfeng Wang, Tao Ouyang
Knowledge of the pathology of axillary lymph nodes (ALN) in breast cancer patients is critical for determining their treatment. Ultrasound is the best noninvasive evaluation for the ALN status. However, the correlation between negative ultrasound results and the sentinel lymph nodes (SLN) pathology remains unknown. To test the hypothesis that negative ultrasound results of ALN predict the negative pathology results of SLN in breast cancer patients, we assessed the association between ALN ultrasonography-negative results and the SLN pathology in 3115 patients with breast cancer recruited between October 2010 and April 2016 from a single cancer center, prospective database...
June 14, 2018: Cancer Medicine
https://www.readbyqxmd.com/read/29903479/computer-aided-prediction-model-for-axillary-lymph-node-metastasis-in-breast-cancer-using-tumor-morphological-and-textural-features-on-ultrasound
#11
Woo Kyung Moon, I-Ling Chen, Ann Yi, Min Sun Bae, Sung Ui Shin, Ruey-Feng Chang
BACKGROUND AND OBJECTIVES: Axillary lymph node (ALN) status is a key indicator in assessing and determining the treatment strategy for patients with newly diagnosed breast cancer. Previous studies suggest that sonographic features of a primary tumor have the potential to predict ALN status in the preoperative staging of breast cancer. In this study, a computer-aided prediction (CAP) model as well as the tumor features for ALN metastasis in breast cancers were developed using breast ultrasound (US) images...
August 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29903054/ultrasound-triggered-drug-delivery-for-breast-tumor-therapy-through-irgd-targeted-paclitaxel-loaded-liposome-microbubble-complexes
#12
Jing Zhang, Song Wang, Zhiting Deng, Li Li, Guanghong Tan, Xin Liu, Hairong Zheng, Fei Yan
Liposome-microbubble complexes (LMC) have become a promising therapeutic carrier for ultrasound-triggered local drug release. However, it is still desirable for the released drugs to be delivered to tumors as effectively as possible. Here, we fabricated iRGD-targeted paclitaxel-loaded liposome-microbubble complexes (iRGD-PTX-LMC) and investigated the feasibility of enhancing the local drug delivery to breast tumors by using these complexes along with ultrasound irradiation. Our results showed that iRGD-modified PTX-loaded liposomes (iRGD-PTX-PL) were successfully conjugated to the surface of microbubbles (MBs) through biotin-avidin linkage...
August 1, 2018: Journal of Biomedical Nanotechnology
https://www.readbyqxmd.com/read/29902347/is-axillary-ultrasound-imaging-necessary-for-all-patients-with-breast-cancer
#13
M Ahmed, M Douek
No abstract text is available yet for this article.
July 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29899537/preliminary-investigation-of-focused-ultrasound-facilitated-drug-delivery-for-the-treatment-of-leptomeningeal-metastases
#14
Meaghan A O'Reilly, Tricia Chinnery, My-Linh Yee, Sheng-Kai Wu, Kullervo Hynynen, Robert S Kerbel, Gregory J Czarnota, Kathleen I Pritchard, Arjun Sahgal
Leptomeningeal metastases (LM) are a serious complication of cancer in the central nervous system (CNS) and are diagnosed in approximately 5% of patients with solid tumors. Effective treatment using systemically administered therapeutics is hindered by the barriers of the CNS. Ultrasound can mediate delivery of drugs through these barriers. The goal of this study was to test the feasibility of using ultrasound-mediated drug delivery to improve the treatment of LM. LM was induced in the spinal cord of athymic rats by injecting HER2-expressing breast cancer cells into the subarachnoid space of the thoracic spine...
June 13, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29899425/triple-negative-invasive-breast-carcinoma-the-association-between-the-sonographic-appearances-with-clinicopathological-feature
#15
Jia-Wei Li, Kai Zhang, Zhao-Ting Shi, Xun Zhang, Juan Xie, Jun-Ying Liu, Cai Chang
In this study, we aimed to evaluate the clinical and pathological factors that associated with sonographic appearances of triple-negative (TN) invasive breast carcinoma. With the ethical approval, 560 patients who were pathologically confirmed as invasive breast carcinoma were reviewed for ultrasound, clinical, and pathological data. Logistic regression analysis was used to identify the typical sonographic features for TN invasive breast carcinomas. The effect of clinical and pathological factors on the sonographic features of TN invasive breast carcinoma was studied...
June 13, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29898762/identifying-an-early-treatment-window-for-predicting-breast-cancer-response-to-neoadjuvant-chemotherapy-using-immunohistopathology-and-hemoglobin-parameters
#16
Quing Zhu, Susan Tannenbaum, Scott H Kurtzman, Patricia DeFusco, Andrew Ricci, Hamed Vavadi, Feifei Zhou, Chen Xu, Alex Merkulov, Poornima Hegde, Mark Kane, Liqun Wang, Kert Sabbath
BACKGROUND: Breast cancer pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) varies with tumor subtype. The purpose of this study was to identify an early treatment window for predicting pCR based on tumor subtype, pretreatment total hemoglobin (tHb) level, and early changes in tHb following NAC. METHODS: Twenty-two patients (mean age 56 years, range 34-74 years) were assessed using a near-infrared imager coupled with an Ultrasound system prior to treatment, 7 days after the first treatment, at the end of each of the first three cycles, and before their definitive surgery...
June 14, 2018: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/29897588/the-effect-of-ultrasound-treatments-on-the-tenderizing-pathway-of-goose-meat-during-conditioning
#17
X Li, Y Wang, Y Y Sun, D D Pan, J X Cao
In order to figure out the effect of ultrasound treatments (UT) on the tenderizing pathway of goose meat, breast muscles of 32 Eastern Zhejiang White Geese were treated with different ultrasound powers (the control, 300 and 600 W) at 40 kHz for 30 min. Shear force, cooking loss, myofibrillar fraction index (MFI), particle size, morphological analysis of actin filaments and the levels of F-actin and G-actin were investigated during 168 h storage. Results showed that 600 W group had the lowest shear force and cooking loss at 24, 48, 96 and 168 h among treatments, while 300 W UT decreased shear force and cooking loss compared to the control...
April 20, 2018: Poultry Science
https://www.readbyqxmd.com/read/29896404/primary-breast-cancer-relapse-as-metastasis-to-the-cervix-uteri-a-case-report
#18
Aude Thouvenot, Yasmine Bizet, Laurent S Baccar, Michele Lamuraglia
Metastasis of non-gynaecological tumours to the cervix is a rare event, and metastasis from breast cancer is even rarer, with only a limited number of such cases reported in the literature to date. We herein report the case of an 86-year-old female patient who had undergone mastectomy and axillary lymphadenectomy for invasive ductal cell breast carcinoma 2 years prior, followed by adjuvant hormonal therapy with letrozole. During hospitalization for anemia associated with an inflammatory syndrome and abdominal pain with menorrhagia, an abdominal ultrasound examination revealed a suspicious uterine mass with irregular contours and abnormal vascularization with associated increase of the blood level of cancer antigen 15-3 to 34 kU/l...
July 2018: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29887398/breast-cyst-fluid-analysis-correlations-with-speed-of-sound-using-transmission-ultrasound
#19
Bilal H Malik, John C Klock
RATIONALE AND OBJECTIVES: The purpose of this work is to determine if the speed of sound value of a breast cyst can aid in the clinical management of breast masses. Breast macrocysts are defined as fluid-filled tissue masses >1cm in diameter and are thought to be aberrations of normal development and involution, often associated with apocrine metaplasia. The benign natural history of breast cysts is well known, and it is important to obtain high specificity in breast imaging to avoid unnecessary biopsies in women who have benign diseases, particularly those with dense breast tissue...
June 7, 2018: Academic Radiology
https://www.readbyqxmd.com/read/29887291/radiological-study-to-evaluate-the-spreading-of-two-volumes-10-vs-20ml-of-radiological-contrast-in-the-block-of-cutaneous-branches-of-intercostal-nerves-in-medial-axillary-line-brilma-in-a-porcine-experimental-model
#20
O Varela, A Melone, R López-Menchaca, R Sevilla, D Callejo, S López-Álvarez, A Román Fernández, S García, I Mantilla, M Zaballos
OBJECTIVE: Interfascial blocks of the thoracic wall are being developed as an alternative to central blocks in breast surgery. However, there are few studies that have evaluated the anatomical extension of the local anaesthetic. The objective of this study was to analyse, using fluoroscopy, the spreading of two volumes (10 vs. 20ml) of radiological contrast in the serratus-intercostal plane block in an experimental pig model. MATERIAL AND METHODS: Ten Large-White breed pigs were selected to have a bilateral ultrasound serratus-intercostal plane block performed, with the administering of 10ml and 20ml of iopamidol in the right and left hemithorax, respectively...
June 7, 2018: Revista Española de Anestesiología y Reanimación
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