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https://www.readbyqxmd.com/read/28335472/detecting-breast-cancer-with-a-dual-modality-device
#1
Kamila Padia, Tania S Douglas, Lydia L Cairncross, Roland V Baasch, Christopher L Vaughan
Although mammography has been the gold standard for the early detection of breast cancer, if a woman has dense breast tissue, a false negative diagnosis may occur. Breast ultrasound, whether hand-held or automated, is a useful adjunct to mammography but adds extra time and cost. The primary aim was to demonstrate that our second-generation Aceso system, which combines full-field digital mammography (FFDM) and automated breast ultrasound (ABUS) in a single platform, is able to produce improved quality images that provide clinically meaningful results...
March 18, 2017: Diagnostics
https://www.readbyqxmd.com/read/28335206/cytotoxic-induction-and-photoacoustic-imaging-of-breast-cancer-cells-using-astaxanthin-reduced-gold-nanoparticles
#2
Subramaniyan Bharathiraja, Panchanathan Manivasagan, Nhat Quang Bui, Yun-Ok Oh, In Gweon Lim, Suhyun Park, Junghwan Oh
Astaxanthin, a kind of photosynthetic pigment, was employed for gold nanoparticle formation. Nanoparticles were characterized using Ulteraviolet-Visible (UV-Vis) spectroscopy, transmission electron microscopy, and X-ray diffraction, and the possible presence of astaxanthin functional groups were analyzed by Fourier transform infrared spectroscopy (FTIR). The cytotoxic effect of synthesized nanoparticles was evaluated against MDA-MB-231 (human breast cancer cells) using a tetrazolium-based assay, and synthesized nanoparticles exhibited dose-dependent toxicity...
April 20, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28333404/upgrade-rate-and-imaging-features-of-atypical-apocrine-lesions
#3
Lauren Q Chang Sen, Wendie A Berg, Gloria J Carter
The purpose of our work was to identify imaging features of atypical apocrine lesions and determine the rate of upgrade to ductal carcinoma in situ (DCIS) or invasive carcinoma at excision after such a diagnosis on percutaneous breast biopsy. From January 1, 2006, through October 8, 2013, a total of 33,157 breast core biopsies were performed at University of Pittsburgh Medical Center. Of those, 58 (0.2%) showed atypical apocrine lesions. For 24, atypical apocrine adenosis (AAA) or atypical apocrine metaplasia (AAM) was the only risk lesion, with no known ipsilateral malignancy, and the results of excision were available...
March 23, 2017: Breast Journal
https://www.readbyqxmd.com/read/28332172/quantitative-ultrasound-and-dxa-measurements-in-aromatase-inhibitor-treated-breast-cancer-women-receiving-denosumab
#4
A Catalano, A Gaudio, N Morabito, G Basile, R M Agostino, A Xourafa, M Atteritano, E Morini, G Natale, A Lasco
PURPOSE: Denosumab has been proven to reduce fracture risk in breast cancer (BC) women under aromatase inhibitors (AIs). Quantitative ultrasound (QUS) provides information on the structure and elastic properties of bone. Our aim was to assess bone health by phalangeal QUS and by dual-energy X-ray absorptiometry (DXA), and to evaluate bone turnover in AIs-treated BC women receiving denosumab. METHODS: 35 Postmenopausal BC women on AIs were recruited (mean age 61...
March 22, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28331733/3d-supine-automated-ultrasound-saus-abus-abvs-for-supplemental-screening-women-with-dense-breasts
#5
EDITORIAL
Alexander Mundinger
No abstract text is available yet for this article.
April 2016: J Breast Health (2013)
https://www.readbyqxmd.com/read/28331611/long-term-efficacy-of-ultrasound-guided-high-intensity-focused-ultrasound-treatment-of-breast-fibroadenoma
#6
Roussanka Kovatcheva, Katja Zaletel, Jordan Vlahov, Julian Stoinov
BACKGROUND: To assess the long term efficacy and tolerability of one or two ultrasound (US)-guided high-intensity focused ultrasound (HIFU) treatment in patients with breast fibroadenoma (FA). METHODS: Twenty patients with 26 FA were selected for US-guided HIFU. The therapy was performed in one or two sessions. FA volume was assessed before and followed up to 24 months after the last HIFU. After each treatment, adverse events were evaluated. RESULTS: In 19/26 FA (73...
2017: Journal of Therapeutic Ultrasound
https://www.readbyqxmd.com/read/28331240/minimally-invasive-breast-fibroadenoma-excision-using-an-ultrasound-guided-vacuum-assisted-biopsy-device
#7
Thomas Papathemelis, Stefanie Heim, Michael P Lux, Ines Erhardt, Anton Scharl, Sophia Scharl
Introduction We studied the extent to which an ultrasound-guided vacuum-assisted biopsy device ("hand-held Mammotome") could be used not only as a valuable tool for investigation of suspicious breast lesions, but also therapeutically for the complete removal of breast fibroadenomas. Materials and Methods 132 aspiration biopsies showing fibroadenoma on histology were collected retrospectively. We ascertained whether there were residual findings on breast ultrasound at a median follow-up of approx. 9 months following biopsy...
February 2017: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/28328843/clinical-significance-of-interval-changes-in-breast-lesions-initially-categorized-as-probably-benign-on-breast-ultrasound
#8
Ja Yoon Jang, Sun Mi Kim, Jin Hwan Kim, Mijung Jang, Bo La Yun, Jong Yoon Lee, Soo Hyun Lee, Bohyoung Kim
The aims of this study were to determine the malignancy rate of probably benign lesions that show an interval change on follow-up ultrasound and to evaluate the differences seen on imaging between benign and malignant lesions initially categorized as probably benign but with interval change on follow-up breast ultrasound.We retrospectively reviewed 11,323 lesions from ultrasound-guided core-biopsies performed between June 2004 and December 2014 and identified 289 lesions (266 patients) with an interval change from probably benign (Breast Imaging Reporting and Data System [BI-RADS] category 3) in the previous 2 years...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28328497/synergistic-effects-of-nanodrug-ultrasound-hyperthermia-and-thermal-ablation-on-solid-tumors-an-animal-study
#9
Li-Chen Chiu, Sheng-Kai Wu, Win-Li Lin, Gin-Shin Chen
OBJECTIVE: Delivery barriers of nanodrug in large tumors due to heterogeneous blood supply, elevated interstitial pressure and long transport distances can degrade the efficacy of cancer treatment. In this study, we proposed a therapeutic strategy to improve the tumor growth inhibition by injecting pegylated liposomal doxorubicin (PLD), and then applying a short time of ultrasound hyperthermia (HT) on the entire solid tumor, and inflicting ultrasound thermal ablation (Ab) in the low-perfused tumor region...
March 17, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28327075/magnetic-nanobubbles-with-potential-for-targeted-drug-delivery-and-trimodal-imaging-in-breast-cancer-an-in-vitro-study
#10
Weixiang Song, Yindeng Luo, Yajing Zhao, Xinjie Liu, Jiannong Zhao, Jie Luo, Qunxia Zhang, Haitao Ran, Zhigang Wang, Dajing Guo
AIM: The aim of this study was to improve tumor-targeted therapy for breast cancer by designing magnetic nanobubbles with the potential for targeted drug delivery and multimodal imaging. MATERIALS & METHODS: Herceptin-decorated and ultrasmall superparamagnetic iron oxide (USPIO)/paclitaxel (PTX)-embedded nanobubbles (PTX-USPIO-HER-NBs) were manufactured by combining a modified double-emulsion evaporation process with carbodiimide technique. PTX-USPIO-HER-NBs were examined for characterization, specific cell-targeting ability and multimodal imaging...
March 13, 2017: Nanomedicine
https://www.readbyqxmd.com/read/28321344/pituitary-adenoma-and-hyperprolactinemia-accompanied-by-idiopathic-granulomatous-mastitis
#11
Sebahattin Destek, Vahit Onur Gul, Serkan Ahioglu, Kursat Rahmi Serin
Idiopathic granulomatous mastitis (IGM) is a rare chronic inflammatory disease of the breast, and its etiology remains not fully elucidated. IGM is observed more often in patients with autoimmune disease. Hyperprolactinemia is observed during pregnancy, lactation, and a history of oral contraceptive use. A 39-year-old patient with no history of oral contraceptive use presented with complaints such as redness, pain, and swelling in her left breast. Ultrasound and magnetic resonance imaging (MRI) revealed a suspicious inflamed mass lesion...
2017: Case Reports in Endocrinology
https://www.readbyqxmd.com/read/28320657/regularized-dual-averaging-image-reconstruction-for-full-wave-ultrasound-computed-tomography
#12
Thomas Matthews, Kun Wang, Cuiping Li, Neb Duric, Mark Anastasio
Ultrasound computed tomography (USCT) holds great promise for breast cancer screening. Waveform inversionbased image reconstruction methods account for higher-order diffraction effects and can produce high-resolution USCT images, but are computationally demanding. Recently, a source encoding technique was combined with stochastic gradient descent to greatly reduce image reconstruction times. However, this method bundles the stochastic data fidelity term with the deterministic regularization term. This limitation can be overcome by replacing stochastic gradient descent (SGD) with a structured optimization method, such as the regularized dual averaging (RDA) method, that exploits knowledge of the composition of the cost function...
March 14, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28314842/performance-of-mid-treatment-breast-ultrasound-and-axillary-ultrasound-in-predicting-response-to-neoadjuvant-chemotherapy-by-breast-cancer-subtype
#13
Rosalind P Candelaria, Roland L Bassett, William Fraser Symmans, Maheshwari Ramineni, Stacy L Moulder, Henry M Kuerer, Alastair M Thompson, Wei Tse Yang
BACKGROUND: The primary objective was to determine whether mid-treatment ultrasound measurements of index breast tumors and index axillary nodes of different cancer subtypes associate with residual cancer burden (RCB). METHODS: Patients with invasive breast cancer who underwent neoadjuvant chemotherapy and had pre-treatment and mid-treatment breast and axillary ultrasound were included in this single-institution, retrospective cohort study. Linear regression analysis assessed associations between RCB with (a) change in index breast tumor size, (b) change in index node size, and (c) absolute number of abnormal nodes at mid-treatment...
March 17, 2017: Oncologist
https://www.readbyqxmd.com/read/28301207/second-opinion-review-of-breast-imaging-at-a-cancer-center-is-it-worthwhile
#14
Kristen Coffey, Donna D'Alessio, Delia M Keating, Elizabeth A Morris
OBJECTIVE: Second-opinion review of breast imaging studies can be a time-consuming and labor-intensive process. The purpose of this investigation was to determine whether reinterpretation of studies obtained at institutions outside a cancer center influences clinical management, specifically by revealing additional cancer and preventing unnecessary biopsy. MATERIALS AND METHODS: A review was conducted of breast imaging studies of 200 patients who underwent ultrasound and MRI at community facilities and had the images submitted for second opinions at a cancer center between January and April 2014...
March 16, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28298950/sonography-in-capsular-contracture-after-breast-augmentation-value-of-established-criteria-new-techniques-and-directions-for-research
#15
Johannes Gossner
Capsular contracture or capsular fibrosis is the most common complication following breast augmentation with implants. Sonography is usually the initial imaging test performed to examine a suspicious implant. In contrast to the large number of patients developing capsular fibrosis there is only sparse literature reporting about sonographic findings. In this letter after a brief review of normal sonographic findings after breast augmentation, established ultrasound findings suggestive of capsular fibrosis (deformity, increased number of radial folds and thickening of the fibrous capsule) are discussed...
March 2017: Journal of Ultrasound
https://www.readbyqxmd.com/read/28296665/papillomas-of-the-breast-factors-associated-with-underestimation
#16
Gabriela Boufelli, Marcelo A Giannotti, Carlos A Ruiz, Nestor de Barros, Luciano F Chala, Jonathan Y Maesaka, Rodrigo Goncalves, Bárbara H Bresciani, Paula Vianna, José M Soares, Edmund C Baracat, José R Filassi
The distinction between benign and malignant papilloma of the breast through percutaneous needle biopsy can be difficult because of limited samples; the underestimation rate can be up to 25%. The aim of this study is to identify clinical and histological factors associated with underestimation, invasive ductal carcinoma, or ductal in-situ carcinoma (DCIS) of the breast found in surgical specimens from papillary lesions. This may contribute toward selection of patients for a follow-up strategy without the need for surgical excision...
March 14, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28295791/value-of-breast-mri-for-patients-with-a-biopsy-showing-atypical-ductal-hyperplasia-adh
#17
Keiko Tsuchiya, Naoko Mori, David V Schacht, Deepa Sheth, Gregory S Karczmar, Gillian M Newstead, Hiroyuki Abe
PURPOSE: To evaluate the diagnostic value of dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) for patients with atypical ductal hyperplasia (ADH) in predicting malignant upgrade. MATERIALS AND METHODS: 3T DCE-MRI was performed for 17 patients with ADH (median age 52, range 42-76) proven by stereotactic biopsy (n = 15), and ultrasound-guided biopsy (n = 2) from January 2011 to April 2015. All patients underwent surgical excision after the MRI...
March 10, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28295467/ultrasound-strain-elastography-for-breast-lesions-computer-aided-evaluation-with-quantifiable-elastographic-features
#18
Yang Xiao, Jie Zeng, Xue Zhang, Li-Li Niu, Ming Qian, Cong-Zhi Wang, Hai-Rong Zheng, Rong-Qin Zheng
OBJECTIVES: To develop and evaluate a set of quantifiable elastographic features based on ultrasound real-time strain elastography (SE) in differentiating between benign and malignant breast lesions. METHODS: The SE and conventional B-mode ultrasound images of 226 breast lesions (81 malignant, 145 benign) were obtained from 226 consecutive women. By using a computer-aided tool, four elastographic features (elasticity score, lesion stiffness degree, lesion-to-fat strain ratio, and elastography-to-B-mode lesion area ratio) were respectively calculated and evaluated...
March 10, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28295423/analysis-of-false-negative-readings-of-automated-breast-ultrasound-studies
#19
Ahuva Grubstein, Yael Rapson, Itai Gadiel, Maya Cohen
BACKGROUND: To assess the reasons for false-negative readings of automated breast ultrasound (ABUS) studies. METHODS: Between 2012 and 2015, 1,890 ABUS studies were performed at our tertiary medical center. Those for which false-negative results were documented in the initial ABUS report against the corresponding hand-held ultrasound (HHUS) scan were reviewed by three specialized breast radiologists. Key images of specific lesions were marked on the ABUS and HHUS scans and compared for quality (equal, better with HHUS, better with ABUS)...
March 13, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28293489/a-novel-strategy-to-supercharge-a-deep-inferior-epigastric-artery-perforator-flap-after-port-a-cath-removal
#20
Chad M Teven, Adrian S H Ooi, David W Chang, David H Song
Autologous breast reconstruction using the deep inferior epigastric artery perforator (DIEP) flap has become increasingly popular because of its unique advantages. However, compared with some other forms of abdominal-based autologous reconstruction, DIEP flaps are associated with an increased risk of venous congestion. Many techniques-or lifeboats-have been introduced to diagnose and treat this potentially devastating complication. In this case report, we describe a novel strategy to augment venous drainage when venous congestion is encountered...
December 2016: Plastic and Reconstructive Surgery. Global Open
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