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https://www.readbyqxmd.com/read/28448836/breast-cancer-detection-in-automated-3d-breast-ultrasound-using-iso-contours-and-cascaded-rusboosts
#1
Ehsan Kozegar, Mohsen Soryani, Hamid Behnam, Masoumeh Salamati, Tao Tan
Automated 3D breast ultrasound (ABUS) is a new popular modality as an adjunct to mammography for detecting cancers in women with dense breasts. In this paper, a multi-stage computer aided detection system is proposed to detect cancers in ABUS images. In the first step, an efficient despeckling method called OBNLM is applied on the images to reduce speckle noise. Afterwards, a new algorithm based on isocontours is applied to detect initial candidates as the boundary of masses is hypo echoic. To reduce false generated isocontours, features such as hypoechoicity, roundness, area and contour strength are used...
April 20, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28447112/-imaging-diagnostics-of-breast-metastases-from-extramammary-tumors
#2
REVIEW
S Wienbeck, S Nemat, J Lotz, A Surov
Breast metastases of solid extramammary tumors are very rare in comparison to primary malignancies of the breast and account for only 0.33-6.3% of all malignant neoplasms of the breast. The most common primary tumors are malignant melanoma, distant sarcomas, lung cancer, ovarian cancer, renal cell cancer and thyroid cancer in decreasing order of frequency. This review article summarizes the clinical features and the different imaging findings of breast metastases from different extramammary solid tumors. Breast metastases are often incidental findings in computed tomography (CT) or positron emission tomography CT (PET-CT) imaging...
April 26, 2017: Der Radiologe
https://www.readbyqxmd.com/read/28442932/granular-cell-tumor-in-breast-a-case-report
#3
Maria Castillo Lara, Antonia Martínez Herrera, Rafael Torrejón Cardoso, Daniel Maria Lubián López
Granular cell tumor (GCT) is a rare neoplasm of the soft tissues, and <1% of all GCTs are malignant. It usually appears in the tongue and sometimes may affect the female breast. Initially, GCT was considered to be a myogenic lesion affecting female breast (myoblastoma). Actually, it is assumed as a tumor originating from perineural or putative Schwann cells of peripheral nerves or their precursors that grows in the lobular breast tissue, due to the immunohistochemical features. Here, we review the importance of differentiating between this tumor and malignant breast carcinoma...
2017: Breast Cancer: Targets and Therapy
https://www.readbyqxmd.com/read/28438672/the-management-strategy-of-benign-solitary-intraductal-papilloma-on-breast-core-biopsy
#4
Dayoung Ko, Eunyoung Kang, So Yeon Park, Sun Mi Kim, Mijung Jang, Bo La Yun, Sumin Chae, Yerang Jang, Hye Jin Kim, Sung-Won Kim, Eun-Kyu Kim
BACKGROUND: Intraductal papilloma (IDP) is well-known as one of the common benign breast lesions requiring excision. However, treatment of IDP without atypia is controversial. The aim of our study was to determine the proper management of solitary IDP by core needle biopsy (CNB). PATIENTS AND METHODS: We retrospectively reviewed patients with solitary IDP confirmed by CNB from March 2003 to March 2015. We collected data about final pathology after excision, as well as clinical, histologic, and radiologic findings at initial diagnosis...
April 1, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28437222/laparoscopic-anatomical-segment-2-segmentectomy-by-the-glissonian-approach
#5
Kit-Man Ho, Ho-Seong Han, Yoo-Seok Yoon, Jai Young Cho, Young Rok Choi, Jae Seong Jang, Seong Uk Kwon, Sungho Kim, Jang Kyu Choi
BACKGROUND: When hepatocellular carcinoma (HCC) was located in segment 2 (S2), segment-oriented hepatectomy was more beneficial than left lateral sectionectomy as this type of anatomical resection preserved the volume of the nontumor-bearing segment. Herein, we presented 2 cases (1 with video) of laparoscopic anatomical S2 segmentectomy by the Glissonian approach. METHODS: The first patient was a 69-year-old woman, who had an incidentally detected liver nodule on abdominal ultrasound for systemic surveillance for her breast cancer...
October 19, 2016: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28435467/ultrasound-elastography-review-of-techniques-and-clinical-applications
#6
REVIEW
Rosa M S Sigrist, Joy Liau, Ahmed El Kaffas, Maria Cristina Chammas, Juergen K Willmann
Elastography-based imaging techniques have received substantial attention in recent years for non-invasive assessment of tissue mechanical properties. These techniques take advantage of changed soft tissue elasticity in various pathologies to yield qualitative and quantitative information that can be used for diagnostic purposes. Measurements are acquired in specialized imaging modes that can detect tissue stiffness in response to an applied mechanical force (compression or shear wave). Ultrasound-based methods are of particular interest due to its many inherent advantages, such as wide availability including at the bedside and relatively low cost...
2017: Theranostics
https://www.readbyqxmd.com/read/28435432/foundation-and-methodologies-in-computer-aided-diagnosis-systems-for-breast-cancer-detection
#7
REVIEW
Afsaneh Jalalian, Syamsiah Mashohor, Rozi Mahmud, Babak Karasfi, M Iqbal B Saripan, Abdul Rahman B Ramli
Breast cancer is the most prevalent cancer that affects women all over the world. Early detection and treatment of breast cancer could decline the mortality rate. Some issues such as technical reasons, which related to imaging quality and human error, increase misdiagnosis of breast cancer by radiologists. Computer-aided detection systems (CADs) are developed to overcome these restrictions and have been studied in many imaging modalities for breast cancer detection in recent years. The CAD systems improve radiologists' performance in finding and discriminating between the normal and abnormal tissues...
2017: EXCLI journal
https://www.readbyqxmd.com/read/28433440/spatial-compounding-technique-to-obtain-rotation-elastogram-a-feasibility-study
#8
AliArshad Kothawala, Sowmiya Chandramoorthi, N Ravi Kiran Reddy, Arun Kumar Thittai
The perception of stiffness and slipperiness of a breast mass on palpation is used by physicians to assess the level of suspicion of a lesion as being malignant or benign. However, most current ultrasound elastography imaging methods provide only stiffness-related information. There is no existing approach that provides information about the local rigid body rotation undergone by only a loosely bonded, asymmetrically oriented lesion subjected to a small quasi-static compression. The inherent poor lateral resolution in ultrasound imaging poses a limitation in estimating the local rigid body rotation...
April 19, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28433436/subharmonic-aided-pressure-estimation-for-monitoring-interstitial-fluid-pressure-in-tumors-calibration-and-treatment-with-paclitaxel-in-breast-cancer-xenografts
#9
Valgerdur G Halldorsdottir, Jaydev K Dave, Andrew Marshall, Anya I Forsberg, Traci B Fox, John R Eisenbrey, Priscilla Machado, Ji-Bin Liu, Daniel A Merton, Flemming Forsberg
Interstitial fluid pressure (IFP) in rats with breast cancer xenografts was non-invasively estimated using subharmonic-aided pressure estimation (SHAPE) versus an invasive pressure monitor. Moreover, monitoring of IFP changes after chemotherapy was assessed. Eighty-nine rats (calibration n = 25, treatment n = 64) were injected with 5 × 10(6) breast cancer cells (MDA-MB-231). Radiofrequency signals were acquired (39 rats successfully imaged) with a Sonix RP scanner (BK Ultrasound, Richmond, BC, Canada) using a linear array (L9-4, transmit/receive: 8/4 MHz) after administration of Definity (Lantheus Medical Imaging, North Billerica, MA, USA; 180 μL/kg) and compared with readings from an invasive pressure monitor (Stryker, Berkshire, UK)...
April 19, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28428649/role-of-magnetic-resonance-imaging-in-the-planning-of-breast-cancer-treatment-strategies-comparison-with-conventional-imaging-techniques
#10
Luciana Karla Lira França, Almir Galvão Vieira Bitencourt, Hugo Lamartine Souza Paiva, Caroline Baptista Silva, Nara Pacheco Pereira, Jociana Paludo, Luciana Graziano, Camila Souza Guatelli, Juliana Alves de Souza, Elvira Ferreira Marques
OBJECTIVE: To assess the role of magnetic resonance imaging (MRI) in the planning of breast cancer treatment strategies. MATERIALS AND METHODS: The study included 160 women diagnosed with breast cancer, who underwent breast MRI for preoperative staging. Using Pearson's correlation coefficient (r), we compared the size of the primary tumor, as determined by MRI, by conventional imaging (mammography and ultrasound), and in the pathological examination (gold standard)...
March 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/28427743/microbubble-detection-and-ultrasound-guided-vacuum-assisted-biopsy-of-axillary-lymph-nodes-in-patients-with-breast-cancer
#11
P Britton, P Willsher, K Taylor, F Kilburn-Toppin, E Provenzano, P Forouhi, J Benson, A Agrawal, J R Forman, M G Wallis
AIMS: To assess the feasibility of undertaking microbubble-guided vacuum-assisted biopsy (VAB) of the sentinel lymph node (SLN) and determine its sensitivity in detecting metastases. Patient experience and the impact of VAB on subsequent axillary surgery were also evaluated. MATERIALS AND METHODS: Patients with a normal axillary ultrasound or benign core biopsy planned for surgical SLN biopsy were recruited. Part 1 of the study was used to establish the technique of ultrasound microbubble contrast to detect the SLN...
April 17, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28427629/development-of-a-novel-folate-modified-nanobubbles-with-improved-targeting-ability-to-tumor-cells
#12
Sujuan Duan, Lu Guo, Dandan Shi, Mengmeng Shang, Dong Meng, Jie Li
Conjugation of folate (FOL) to nanobubbles could enhance the selective targeting to tumors expressing high levels of folate receptor (FR). To further improve the selective targeting ability of FOL-modified nanobubbles, a novel FOL-targeted nanobubble ((FOL)2-NB) with increasing FOL content (accomplished by linking two FOL molecules per DSPE-PEG2000 chain) was synthesized, through the methods of mechanical shaking and low-speed centrifugation based on lipid-stabilized perfluoropropane. The bubble size and distribution range were measured by dynamic light scattering (DLS)...
July 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28412952/rayleigh-maximum-likelihood-bilateral-filter-for-ultrasound-image-enhancement
#13
Haiyan Li, Jun Wu, Aimin Miao, Pengfei Yu, Jianhua Chen, Yufeng Zhang
BACKGROUND: Ultrasound imaging plays an important role in computer diagnosis since it is non-invasive and cost-effective. However, ultrasound images are inevitably contaminated by noise and speckle during acquisition. Noise and speckle directly impact the physician to interpret the images and decrease the accuracy in clinical diagnosis. Denoising method is an important component to enhance the quality of ultrasound images; however, several limitations discourage the results because current denoising methods can remove noise while ignoring the statistical characteristics of speckle and thus undermining the effectiveness of despeckling, or vice versa...
April 17, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28412736/tumor-biology-clinicopathological-characteristics-and-prognosis-of-screen-detected-t1-invasive-non-palpable-breast-cancer-in-asymptomatic-chinese-women-2001-2014
#14
Bo Pan, Ru Yao, Yi-Dong Zhou, Qing-Li Zhu, Jie Shi, Qian-Qian Xu, Chang-Jun Wang, Shan-Shan You, Feng Mao, Yan Lin, Song-Jie Shen, Zhi-Yong Liang, Yu-Xin Jiang, Qiang Sun
BACKGROUND: Mammography screening usually detects low-risk breast cancer in the western world. However, little is known about the ultrasound and mammography screen-detected T1 invasive non-palpable breast cancer (NPBC) in asymptomatic Chinese women. RESULTS: With the increase of tumor size (T1a, b, c), lymph node positivity (8.7%, 18.3%, 26.0%, p = 0.018), pN (p = 0.028) and TNM stage (p = 0.035) increased accordingly. Tumor size (T1a, b, c) was correlated with high Ki-67 index (defined as ≥ 14%, 37...
February 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/28411680/mr-imaging-future-imaging-techniques
#15
REVIEW
Lilian C Wang
Breast MR imaging is the most sensitive modality for breast cancer detection. This high sensitivity has led to widespread adoption of this technique, particularly in screening women at elevated risk for breast cancer. Despite its high sensitivity, standard breast MR imaging protocols are limited by moderate specificity and relative higher cost, longer examination time, longer interpretation time, and lower availability compared with mammography and ultrasound. As such, new techniques in MR imaging, including abbreviated breast MR imaging, pharmacokinetic modeling, and diffusion-weighted imaging, are active areas of research...
May 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/28411677/breast-density-legislation-and-clinical-evidence
#16
REVIEW
Regina J Hooley
Breast density inform legislation is widely accepted in the United States and has fueled research regarding the clinical significance of dense breast tissue present on mammography and the value of supplemental screening. This article reviews the origins and current status of breast density inform laws and strategies for optimal breast density determination. Clinical evidence that dense breast tissue is associated with increased breast cancer risk is presented, together with a review of relative risk compared with other risk factors...
May 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/28410763/correlation-between-upper-limb-volume-and-arterial-and-venous-blood-flow-velocity-in-lymphedema-secondary-to-breast-cancer-treatment
#17
Monique Silva Rezende, Ana Luiza Marsengo, Amanda Apolinário, Vânia Tie Koga Ferreira, Elaine Caldeira de Oliveira Guirro
OBJECTIVE: The purpose of this study was to correlate upper limb volume and arterial and venous blood flow velocity in breast cancer survivors. METHODS: A cross-sectional study was conducted on 30 women with lymphedema and a mean age of 55.60 years (standard deviation = 8.12). For the assessment of upper limb volume, perimetry was performed with measures at 6 points on the limb, which were mathematically calculated as volume. The blood flow velocity of the axillary and brachial arteries and veins were assessed by Doppler ultrasound with a probe at 4 MHz...
April 12, 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28409843/reproducibility-of-quantitative-high-throughput-bi-rads-features-extracted-from-ultrasound-images-of-breast-cancer
#18
Yuzhou Hu, Mengyun Qiao, Yi Guo, Yuanyuan Wang, Jinhua Yu, Jiawei Li, Cai Chang
PURPOSE: Digital Breast Imaging Reporting and Data System (BI-RADS) features extracted from ultrasound images are essential in computer-aided diagnosis, prediction, and prognosis of breast cancer. This study focuses on the reproducibility of quantitative high-throughput BI-RADS features in the presence of variations due to different segmentation results, various ultrasound machine models, and multiple ultrasound machine settings. METHODS: Data set 1 consists of 399 patients with invasive breast cancer and is used as the training set to measure the reproducibility of features, while data set 2 consists of 138 other patients and is a validation set used to evaluate the diagnosis performances of the final reproducible features...
April 13, 2017: Medical Physics
https://www.readbyqxmd.com/read/28409837/clinical-accuracy-of-preoperative-breast-mri-for-breast-cancer
#19
Jennifer Tseng, Alexandra Kyrillos, Erik Liederbach, Georgia G Spear, Jacob Ecanow, Chi-Hsiung Wang, Tom Czechura, Olga Kantor, Megan Miller, David J Winchester, Catherine E Pesce, Sarah Rabbitt, Katharine Yao
BACKGROUND: It is unclear if breast magnetic resonance imaging (MRI) is more accurate than mammography (MGM) and ultrasound (U/S) in aggregate for patients with invasive cancer. METHODS: We compared concordance of combined tumor size and tumor foci between MRI and MGM and U/S combined to pathological tumor size and foci as the gold standard from 2009 to 2015. Tumor size was nonconcordant if it differed from the pathologic size by ≥33% and tumor foci was nonconcordant if >1 foci were seen...
April 13, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28409065/malignant-clear-cell-hidradenoma-of-the-breast
#20
Isaac Chambers, Ahmad K Rahal, Pavan S Reddy, K James Kallail
A 58-year-old female had a mass in the right breast palpable beneath the areola. A mammogram revealed a 1.5-centimeter soft tissue density that was confirmed with a subsequent ultrasound. The patient underwent a core needle biopsy which was initially reported as a moderately differentiated invasive ductal carcinoma. Immunohistochemical analysis revealed negative staining for estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor (HER2), mammaglobin, and gross cystic disease fluid protein 15 (GCDFP-15)...
March 1, 2017: Curēus
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