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https://www.readbyqxmd.com/read/29048710/correlations-among-ultrasound-guided-diffuse-optical-tomography-microvessel-density-and-breast-cancer-prognosis
#1
Sihua Niu, Qingli Zhu, Yuxin Jiang, Jiaan Zhu, Mengsu Xiao, Shanshan You, Weixun Zhou, Yu Xiao
OBJECTIVES: To investigate the correlation among ultrasound-guided diffuse optical tomography (DOT), microvessel density, and breast cancer prognosis. METHODS: Before surgery, the total hemoglobin (Hb) concentrations of 184 female patients with breast cancer with only a single lesion were measured. During follow-up, 23 patients had recurrence or metastatic disease after surgery. Among these patients, 18 with recurrence or metastatic disease within 3 years after surgery were paired with 18 patients without recurrence or metastatic disease...
October 19, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29047774/feasibility-study-of-high-spatial-resolution-multimodality-fluorescence-tomography-in-ex-vivo-biological-tissue
#2
Tiffany C Kwong, Farouk Nouizi, Jaedu Cho, Yuting Lin, Uma Sampathkumaran, Gultekin Gulsen
Previously, we demonstrated that temperature-modulated fluorescence tomography (TM-FT) could provide fluorescence images with high quantitative accuracy and the spatial resolution of focused ultrasound. TM-FT is based on scanning the focused ultrasound across the medium to activate temperature-reversible fluorescent nanoprobes (ThermoDots). This technique can resolve small fluorescent targets located several centimeters deep in turbid media with millimeter resolution. Our past studies with this multimodality technique used agar phantoms, which could not represent the true heterogeneous nature of the acoustic and optical properties of biological tissue...
October 1, 2017: Applied Optics
https://www.readbyqxmd.com/read/29046597/ultrasound-tomography-imaging-with-waveform-sound-speed-parenchymal-changes-in-women-undergoing-tamoxifen-therapy
#3
Mark Sak, Neb Duric, Peter Littrup, Mark Sherman, Gretchen Gierach
Ultrasound tomography (UST) is an emerging modality that can offer quantitative measurements of breast density. Recent breakthroughs in UST image reconstruction involve the use of a waveform reconstruction as opposed to a ray-based reconstruction. The sound speed (SS) images that are created using the waveform reconstruction have a much higher image quality. These waveform images offer improved resolution and contrasts between regions of dense and fatty tissues. As part of a study that was designed to assess breast density changes using UST sound speed imaging among women undergoing tamoxifen therapy, UST waveform sound speed images were then reconstructed for a subset of participants...
March 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/29045183/supplemental-screening-with-automated-breast-ultrasound-in-women-with-dense-breasts-comparing-notification-methods-and-screening-behaviors
#4
Allison Aripoli, Kelly Fountain, Onalisa Winblad, Jason Gatewood, Jacqueline Hill, Jo A Wick, Marc Inciardi
OBJECTIVE: Supplemental screening with ultrasound has been shown to detect additional breast malignancies in women with dense breast tissue and normal mammogram findings. The frequency of supplemental screening with automated breast ultrasound and the effect and type of breast tissue density notification on automated screening breast ultrasound utilization rates are unknown. MATERIALS AND METHODS: We examined normal mammogram results letters for patients with heterogeneously or extremely dense breast tissue between July 1, 2013, and June 30, 2014, by type of results letter, notification method, and sociodemographic characteristics...
October 18, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29043992/correlation-of-the-ultrasound-imaging-of-breast-cancer-and-the-expression-of-molecular-biological-indexes
#5
Jie Xu, Feng Li, Fengling Chang
This paper aims to 137 cases of breast malignant tumors confirmed by surgery and pathology were collected. All patients received ultrasound examination and were not treated by radiotherapy or chemotherapy before operation. The preoperative ultrasound images of breast cancer patients and postoperative pathological characteristics of paraffin sections were retrospectively observed. Ultrasound indicators included tumor size, shape, ratio of the longest/shortest dimension, edge of the spiculation and peripheral hyperechoic halo sign, internal echo types, micro calcification, posterior echo types, blood flow and signs of lymph node metastasis...
July 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29043600/effects-of-ultrasound-guided-stellate-ganglion-block-on-sleep-and-regional-cerebral-oxygen-saturation-in-patients-undergoing-breast-cancer-surgery-a-randomized-controlled-double-blinded-trial
#6
Feng Jin, Xiao-Qian Li, Wen-Fei Tan, Hong Ma, Bo Fang, A-Yong Tian, Huang-Wei Lu
Numerous factors could contribute to sleep disturbances in women with breast cancer. We hypothesized that stellate ganglion block (SGB) during surgery would preserve sleep after surgery and increase intraoperative regional cerebral oxygen saturation (rSO2) on the blocked side in patients undergoing breast cancer surgery. A randomized, double-blinded, controlled trial was conducted at the First Hospital of China Medical University from January 2016 to September 2016. Ninety-six patients who underwent radical breast cancer surgery requiring general anaesthesia were randomly assigned to one of two study groups: a control group that received a saline SGB and a block group that received a 0...
October 17, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/29043471/nanostructured-lipid-carrier-co-loaded-with-doxorubicin-and-docosahexaenoic-acid-as-a-theranostic-agent-evaluation-of-biodistribution-and-antitumor-activity-in-experimental-model
#7
Renata S Fernandes, Juliana O Silva, Samuel V Mussi, Sávia C A Lopes, Elaine A Leite, Geovanni D Cassali, Valbert N Cardoso, Danyelle M Townsend, Patrick M Colletti, Lucas A M Ferreira, Domenico Rubello, André L B de Barros
PURPOSE: Nanotheranostic platforms, i.e., the combination of both therapeutic and diagnostic agents on a single platform, are emerging as an interesting tool for the personalized cancer medicine. Therefore, the aim of this work was to evaluate the in vivo properties of a Tc-99m-labeled nanostructured lipid carrier (NLC) formulation, co-loaded with doxorubicin (DOX) and docosahexaenoic acid (DHA), for theranostic applications. PROCEDURES: NLC-DHA-DOX were prepared busing the hot melting homogenization method using an emulsification-ultrasound and were radiolabeled with Tc-99m...
October 17, 2017: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/29043441/patients-view-of-routine-follow-up-after-breast-cancer-treatment
#8
Vesna Bjelic-Radisic, Martha Dorfer, Karl Tamussino, Elfriede Greimel
BACKGROUND: To assess emotional distress, anxiety and stress reactions in breast cancer (BC) patients before the follow-up visits. STUDY DESIGN: Between September 2009 and December 2011 a total of 284 patients completed the BC-psychosocial assessment screening scale (PASS) and a questionnaire about their views of follow-up after treatment for BC. RESULTS: Of the patients 64% reported low level of distress on the BC-PASS. The mean scores on the physical well-being scale was 5...
October 17, 2017: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/29035756/lymph-node-wire-localization-post-chemotherapy-towards-improving-the-false-negative-sentinel-lymph-node-biopsy-rate-in-breast-cancer-patients
#9
Brittany Z Dashevsky, Ashley Altman, Hiroyuki Abe, Nora Jaskowiak, Jean Bao, David V Schacht, Deepa Sheth, Kirti Kulkarni
PURPOSE: To evaluate whether the disease status of the pre-neoadjuvant chemotherapy (NAC) core biopsied lymph node (preNACBxLN) in patients with node positive breast cancer corresponds to nodal status of all surgically retrieved lymph nodes (LNs) post-NAC and whether wire localization of this LN is feasible. MATERIALS AND METHODS: HIPPA compliant IRB approved retrospective study including breast cancer patients (a.) with preNACBxLN confirmed metastases, (b.) who received NAC, and (c...
October 7, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/29033094/necessity-of-axillary-scanning-after-negative-finding-on-both-mammography-and-subsequent-breast-ultrasound
#10
Inyoung Youn, Jung Hyun Yoon, Ji Hyun Youk, Hee Jung Moon, Min Jung Kim, Eun-Kyung Kim, Jai Kyung You
The purpose of our study was to assess the cancer detection rate and positive predictive value (PPV) for incidentally detected abnormal axillary lymph nodes with negative mammography and subsequent breast ultrasound (US). We included 7039 screened patients (mean age, 52 y) from January 2012 to March 2015 with negative mammography and subsequent breast US results. In two patients with positive lymph nodes, neither were from breast malignancy. The calculated cancer detection rate, PPV for biopsy and axillary biopsy rate was 0...
October 12, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29031099/shear-wave-elastography-for-characterization-of-breast-lesions-shearlet-transform-and-local-binary-pattern-histogram-techniques
#11
U Rajendra Acharya, Wei Lin Ng, Kartini Rahmat, Vidya K Sudarshan, Joel E W Koh, Jen Hong Tan, Yuki Hagiwara, Arkadiusz Gertych, Farhana Fadzli, Chai Hong Yeong, Kwan Hoong Ng
Shear wave elastography (SWE) examination using ultrasound elastography (USE) is a popular imaging procedure for obtaining elasticity information of breast lesions. Elasticity parameters obtained through SWE can be used as biomarkers that can distinguish malignant breast lesions from benign ones. Furthermore, the elasticity parameters extracted from SWE can speed up the diagnosis and possibly reduce human errors. In this paper, Shearlet transform and local binary pattern histograms (LBPH) are proposed as an original algorithm to differentiate malignant and benign breast lesions...
October 2, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29030785/usefulness-of-abbreviated-breast-mri-screening-for-women-with-a-history-of-breast-cancer-surgery
#12
Bo Hwa Choi, Nami Choi, Mi Young Kim, Jung-Hyun Yang, Young Bum Yoo, Hae Kyoung Jung
PURPOSE: We investigated the usefulness of abbreviated breast MRI (AB-MRI), including fat-suppressed T2-weighted imaging, pre- and postcontrast image acquisition, and subtracted maximum-intensity projection imaging, for the screening of women with a history of breast cancer surgery. METHODS: Between October 2014 and March 2016, a total of 799 AB-MRI examinations were performed for 725 women with a history of breast cancer surgery. The image acquisition time was 8...
October 13, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29030106/the-shift-from-sentinel-lymph-node-biopsy-performed-either-before-or-after-neoadjuvant-systemic-therapy-in-the-clinical-negative-nodes-of-breast-cancer-patients-results-and-the-advantages-and-disadvantages-of-both-procedures
#13
Sergi Fernandez-Gonzalez, Catalina Falo, Maria Jesus Pla, Sonia Pernas, Maite Bajen, Teresa Soler, Raul Ortega, Cecilia Quetglas, Xavier Perez-Martin, Maria Eulalia Fernandez Montoli, Miriam Campos, Mar Varela-Rodriguez, Jordi Ponce, Amparo Garcia-Tejedor
BACKGROUND: In patients with breast cancer who are candidates for neoadjuvant therapy (NAT), the timing of when to perform sentinel lymph node biopsy (SLNB) remains under discussion. The aim of this study was to compare the advantages and disadvantages of SLNB performed before and after NAT. PATIENTS AND METHODS: One hundred seventy-two patients, T1c to T3 and N0 (clinically and according to ultrasound) candidates for NAT were included. We compared the outcomes of 2 groups: (1) 122 patients of whom SLNB was performed before NAT (pre-NAT) from December 2006 to April 2014; and (2) 50 patients with SLNB performed after NAT (post-NAT) from May 2014 to July 2016...
September 4, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/29027318/imaging-and-pathology-features-to-predict-axillary-tumor-load-in-breast-cancer
#14
Pau Nicolau, Rocio Gamero, Ana Rodríguez-Arana, Francisco Plancarte, Rodrigo Alcántara, Ramon Carreras, Dolors Sabadell, Mar Vernet-Tomas
AIM: We investigated if imaging and pathology features could help to identify a high axillary tumor burden (ATB) in breast cancer patients, in order to individualize decisions on axillary lymph node (ALN) dissection (ALND). METHODS: We retrospectively analyzed patients primarily treated with surgery in our unit between 2011 and 2014. We divided the patients in two groups: low ATB (LATB) if ≤ 2 ALN were infiltrated and high ATB (HATB) if > 2 ALN were infiltrated...
October 13, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29025210/up-to-date-doppler-techniques-for-breast-tumor-vascularity-superb-microvascular-imaging-and-contrast-enhanced-ultrasound
#15
Ah Young Park, Bo Kyoung Seo
Ultrasonographic Doppler techniques have improved greatly over the years, allowing more sophisticated evaluation of breast tumor vascularity. Superb microvascular imaging (SMI) and contrast-enhanced ultrasound (CEUS) with second-generation contrast agents are two representative up-to-date techniques. SMI is a sensitive Doppler technique that adopts an intelligent filter system to separate low-flow signals from artifacts. With the development of second-generation contrast agents, CEUS has also emerged as a useful Doppler technique for evaluating tumor microcirculation...
August 19, 2017: Ultrasonography
https://www.readbyqxmd.com/read/29024674/optic-nerve-head-problem
#16
Rohan Verma, Kevin C Chen, Hema L Ramkumar, Michael H Goldbaum, Carol L Shields
A 68-year-old woman with a recent history of blurring in the left eye had undergone mastectomy for breast cancer twenty years ago. A series of bone metastases started five years after her diagnosis. Examination of the optic nerve head of the left eye revealed an isolated epipapillary mass. Indocyanine green angiography displayed vessels within the mass, and fluorescein angiography demonstrated hyperfluorescence of the mass from vascular leakage plus lobular spots of blocked fluorescence. B-scan ultrasound revealed a hyperechoic elevated nodular mass on the optic disc...
October 9, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/29024424/developing-asymmetry-in-a-screening-mammogram-a-cautionary-tale-of-a-missed-cancer
#17
Jane Peart, Glen Thomson, Stephen Wood
The developing asymmetry has a 12-15% risk of malignancy but poses challenges of detection and interpretation due to the lack of typical features of cancer and the frequent absence of an ultrasound correlate. Failure to biopsy these lesions may lead to delayed diagnosis of breast cancer.
October 11, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29024198/mucocele-like-lesions-diagnosed-on-breast-core-biopsy-low-risk-of-upgrade-and-subsequent-carcinoma
#18
Gloria Zhang, Dana Ataya, Paulette L Lebda, Benjamin C Calhoun
Mucocele-like lesions of the breast diagnosed on core biopsy are usually excised to exclude the possibility of partial sampling of an invasive mucinous carcinoma. The goal of this study was to correlate the pathologic and radiologic features of mucocele-like lesions to determine if excision is mandatory. Over a 16 year period we identified 32 patients with mucocele-like lesions diagnosed on 27 (84%) stereotactic and 5 (16%) ultrasound-guided core biopsies. The indications for core biopsy were: calcifications in 24 (75%), a mass in 7 (22%), and a mass with calcifications in 1 (3%)...
October 11, 2017: Breast Journal
https://www.readbyqxmd.com/read/29018952/automated-breast-volume-scanner-abvs-in-assessing-breast-cancer-size-a-comparison-with-conventional-ultrasound-and-magnetic-resonance-imaging
#19
Rossano Girometti, Martina Zanotel, Viviana Londero, Anna Linda, Michele Lorenzon, Chiara Zuiani
OBJECTIVES: To compare automated breast volume scanner (ABVS), ultrasound (US) and MRI in measuring breast cancer size, and evaluate the agreement between ABVS and US in assessing lesion location and sonographic features. METHODS: We retrospectively included 98 women with 100 index cancers who had undergone US and ABVS followed by 1.5T MRI. Images were interpreted by a pool of readers reporting lesion size, location and breast imaging reporting and data system (BI-RADS) features...
October 10, 2017: European Radiology
https://www.readbyqxmd.com/read/29016551/pectoral-fascial-pecs-i-and-ii-blocks-as-rescue-analgesia-in-a-patient-undergoing-minimally-invasive-cardiac-surgery
#20
Suraj Yalamuri, Rebecca Y Klinger, W Michael Bullock, Donald D Glower, Brandi A Bottiger, Jeffrey C Gadsden
INTRODUCTION: Patients undergoing minimally invasive cardiac surgery have the potential for significant pain from the thoracotomy site. We report the successful use of pectoral nerve block types I and II (Pecs I and II) as rescue analgesia in a patient undergoing minimally invasive mitral valve repair. CASE REPORT: In this case, a 78-year-old man, with no history of chronic pain, underwent mitral valve repair via right anterior thoracotomy for severe mitral regurgitation...
October 6, 2017: Regional Anesthesia and Pain Medicine
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