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https://www.readbyqxmd.com/read/29457674/a-review-of-brain-stimulation-methods-to-treat-substance-use-disorders
#1
REVIEW
Alexandria S Coles, Karolina Kozak, Tony P George
BACKGROUND: Substance use disorders (SUDs) are a leading cause of disability worldwide. While several pharmacological and behavioral treatments for SUDs are available, these may not be effective for all patients. Recent studies using non-invasive neuromodulation techniques including Repetitive Transcranial Magnetic Stimulation (rTMS), Transcranial Direct Current Stimulation (tDCS), and Deep Brain Stimulation (DBS) have shown promise for SUD treatment. OBJECTIVE: Multiple studies were evaluated investigating the therapeutic potential of non-invasive brain stimulation techniques in treatment of SUDs...
February 19, 2018: American Journal on Addictions
https://www.readbyqxmd.com/read/29456448/pain-catastrophizing-mediates-the-relationship-between-trait-happiness-and-depressive-symptoms-in-individuals-with-current-pain
#2
Patrick Tran, John A Sturgeon, Aneesha Nilakantan, Alyssa Foote, Sean Mackey, Kevin Johnson
Objective: There is an extensive relationship between chronic pain and depression; however, there is less research examining whether pain-specific factors, such as pain intensity, predict depression, above and beyond the role of normative factors, such as positive emotions. The current study characterized the independent contributions of pain intensity, pain catastrophizing, and a trait measure of happiness to self-rated depressive symptoms. Methods: We recruited and enrolled 70 volunteers across 3 groups of participants: two groups of patients with current low back pain (one group on opioids and one group opioid-naïve), and individuals in a methadone maintenance treatment program...
December 2017: Journal of Applied Biobehavioral Research
https://www.readbyqxmd.com/read/29456355/role-of-yoga-in-management-of-substance-use-disorders-a-narrative-review
#3
REVIEW
Pooja Patnaik Kuppili, Arpit Parmar, Ankit Gupta, Yatan Pal Singh Balhara
Substance use disorders are comparable to chronic medical illnesses and have a chronic relapsing course. Despite being significant contributors to morbidity and mortality, limited treatment options exist. The current narrative review was aimed at providing an overview of yoga therapy in substance-use disorders and discuss the relevant methodological issues. Articles published in English language till May 2017 indexed with PubMed, PubMed central, and Google Scholar were searched using search terms "Yoga," "Substance use," "Drug dependence," "Nicotine," "Tobacco," "Alcohol," "Opioids," "Cannabis," "Cocaine," "Stimulants," "Sedative hypnotics," "Inhalants," and "Hallucinogens" for inclusion in the review...
January 2018: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/29456150/antidepressants-as-antipruritic-agents-a-review
#4
REVIEW
Randeep Kaur, V R Sinha
Pruritus is a concomitant symptom of various underlying disorders viz. dermatological, systemic and psychiatric disorders that provoke the person to scratch the skin. Many natural as well as, antipruritic therapies are usually practiced in the treatment of pruritus including general preventive measures, topical therapies such as cooling agents, antihistamines, anesthetics, capsaicin, corticosteroids, immunomodulators and; systemic therapies including administration of antihistamines, opioid antagonists/agonists, antiepileptic drugs/neuroleptics (e...
February 15, 2018: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29456094/association-among-opioid-use-treatment-preferences-and-perceptions-of-physician-treatment-recommendations-in-patients-with-neck-and-back-pain
#5
William B Weeks, Christine M Goertz, Cynthia R Long, William C Meeker, Dennis M Marchiori
OBJECTIVE: The purpose of this study was to explore the relationship between self-reported use of opioids by patients with neck and back pain and their demographics, pain characteristics, treatment preferences, and recollections of their physicians' opinions regarding treatment options. METHODS: We analyzed 2017 Gallup Poll survey data from 1680 US adults who had substantial spine pain in the past year and used logistic regression to explore the aforementioned relationships...
February 15, 2018: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/29454333/comparative-study-of-ultrasound-guided-paravertebral-block-versus-intravenous-tramadol-for-postoperative-pain-control-in-percutaneous-nephrolithotomy
#6
Zehra Hatipoglu, Ersel Gulec, Mediha Turktan, Volkan Izol, Atilla Arıdogan, Yasemin Gunes, Dilek Ozcengiz
BACKGROUND: Percutaneous nephrolithotomy (PCNL) is a minimally invasive surgical procedure for renal calculi, and nephrostomy tubes lead to postoperative pain after PCNL. Regional techniques (e.g., epidural analgesia and peripheral blocks) and opioids are applied for postoperative pain treatment. The aim of this study was to compare effectiveness of ultrasound-guided paravertebral block (PVB) and tramadol on postoperative pain in patients who underwent PCNL. METHOD: Fifty-three patients were included in this prospective randomized study...
February 17, 2018: BMC Anesthesiology
https://www.readbyqxmd.com/read/29454083/incidence-of-acute-suppurative-sialadenitis-in-end-stage-cancer-patients-a-retrospective-observational-study
#7
Hiroaki Watanabe, Takuya Odagiri, Yasuyuki Asai
CONTEXT: Acute suppurative sialadenitis (hereafter referred to as sialadenitis) is accompanied by pain and fever and can diminish the quality of life (QOL) in end-stage cancer patients; however, its incidence is not clear. OBJECTIVES: We conducted this study to elucidate the incidence of sialadenitis in end-stage cancer patients. METHODS: Retrospective review, observational study based on patients' medical records SUBJECTS: 726 consecutive cancer patients who died on the palliative care unit of our hospital between April 2012 and November 2016 were included...
February 14, 2018: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/29453925/impact-of-opioid-therapy-on-gonadal-hormones-focus-on-buprenorphine
#8
REVIEW
Anjali Varma, Mamta Sapra, Ali Iranmanesh
Objective The USA is in the midst of an opioid crisis. Understanding the impact of opioids and commonly used treatments for opioid dependence is essential for clinicians and researchers in order to educate and treat the nation's growing population with opioid use disorders. As a relatively new treatment for opioid dependence, buprenorphine is gaining popularity to the extent of becoming not only a preferred approach to the maintenance of opiate addiction, but also an option for chronic pain management. The purpose of this report is to review the available evidence on the endocrine effects of buprenorphine, particularly as it relates to the hypothalamic-pituitary-gonadal (HPG) axis, which is controversial and not fully defined...
February 17, 2018: Hormone Molecular Biology and Clinical Investigation
https://www.readbyqxmd.com/read/29453891/an-investigation-of-an-open-access-model-for-scaling-up-methadone-maintenance-treatment
#9
Lynn M Madden, Scott O Farnum, Kathryn F Eggert, Andrew R Quanbeck, Robert Freeman, Samuel A Ball, Richard S Schottenfeld, Julia M Shi, Mary Ellen Savage, Declan T Barry
AIMS: To retrospectively examine patient and programmatic outcomes following the development and implementation of an "open-access" model in which prospective patients were enrolled rapidly in methadone maintenance treatment, irrespective of ability to pay, and provided real-time access to multiple voluntary treatment options. DESIGN: Medical and administrative records were abstracted to compare data for one year before and 9 years after initiating the implementation of an open-access treatment model in May 2007...
February 17, 2018: Addiction
https://www.readbyqxmd.com/read/29452834/pain-and-analgesic-drugs-in-chronic-venous-ulcers-with-topical-sevoflurane-use
#10
Adrian Imbernon-Moya, Francisco Javier Ortiz-de Frutos, Mónica Sanjuan-Alvarez, Isabel Portero-Sanchez, Raúl Merinero-Palomares, Victoria Alcazar
OBJECTIVE: Pain in chronic venous ulcers (CVUs) notably increases with the usual cleaning of the wound. Chronic pain is usually poorly controlled even with the multiple analgesic treatments available. Analgesics can have different serious adverse effects and medical interactions in old patients with several comorbidities. This study reports the efficacy and safety of topical sevoflurane for treatment of pain in CVUs. METHODS: We report a descriptive and retrospective study of 30 patients older than 65 years with painful CVUs refractory to conventional analgesic treatments...
February 13, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29452704/substance-use-disorder-among-current-cancer-patients-rates-and-correlates-nationally-in-the-department-of-veterans-affairs
#11
Pochu Ho, Robert Rosenheck
BACKGROUND: Substance use disorders (SUDs) are known to cause or complicate treatment of many types of cancers. OBJECTIVES: We sought to systematically assess rates of current SUDs among patients currently in treatment for cancer. METHODS: The National Veteran Health Administration administrative data from fiscal year 2012 were used to compare veterans with both cancer and comorbid SUDs to veterans with cancer but no SUDs and those with a SUD but no cancer...
January 10, 2018: Psychosomatics
https://www.readbyqxmd.com/read/29451660/economic-assessment-of-postoperative-pain-control-strategies-for-treatment-of-adult-patients-with-cancer
#12
Rafael Freitas Dos Santos, Fernando Bliacheriene, Flavia Mori Sarti
OBJECTIVE: The authors performed an economic assessment of opioids currently being used for control of postoperative pain relating to the surgical treatment of cancer (fentanyl and sufentanil) within the Brazilian Unified Health System (SUS, in the Portuguese acronym). METHOD: The assessment was based on the perspective of the government, in order to collaborate with the promotion of effectiveness in public policies of health, and to optimize the allocation of public resources into health...
November 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/29451426/prioritizing-pediatric-chronic-pain-and-comprehensive-pain-treatment-in-the-context-of-the-opioid-epidemic
#13
Sarah R Martin, Lonnie K Zeltzer
No abstract text is available yet for this article.
February 16, 2018: Pain Management
https://www.readbyqxmd.com/read/29450244/characteristics-of-adherence-to-methadone-maintenance-treatment-over-a-15-year-period-among-homeless-adults-experiencing-mental-illness
#14
Milad Parpouchi, Akm Moniruzzaman, Stefanie N Rezansoff, Angela Russolillo, Julian M Somers
Background: Methadone maintenance treatment (MMT) has important protective effects related to reduced illicit opioid use, infectious disease transmission, and overdose mortality. Adherence to MMT has not been examined among homeless people. We measured MMT adherence and reported relevant characteristics among homeless adults experiencing mental illness in Vancouver, British Columbia, Canada. Material and methods: Homeless adults living with mental illness who had received MMT prior to the baseline interview of the Vancouver At Home study ( n = 78) were included in analyses...
December 2017: Addictive Behaviors Reports
https://www.readbyqxmd.com/read/29450233/pharmacogenomics-guided-policy-in-opioid-use-disorder-oud-management-an-ethnically-diverse-case-based-approach
#15
Earl B Ettienne, Edwin Chapman, Mary Maneno, Adaku Ofoegbu, Bradford Wilson, Beverlyn Settles-Reaves, Melissa Clarke, Georgia Dunston, Kevin Rosenblatt
Introduction: Opioid use disorder (OUD) is characterized by a problematic pattern of opioid use leading to clinically-significant impairment or distress. Opioid agonist treatment is an integral component of OUD management, and buprenorphine is often utilized in OUD management due to strong clinical evidence for efficacy. However, interindividual genetic differences in buprenorphine metabolism may result in variable treatment response, leaving some patients undertreated and at increased risk for relapse...
December 2017: Addictive Behaviors Reports
https://www.readbyqxmd.com/read/29450210/sofosbuvir-based-direct-acting-antiviral-therapies-for-hcv-in-people-receiving-opioid-substitution-therapy-an-analysis-of-phase-3-studies
#16
Jason Grebely, Jordan J Feld, David Wyles, Mark Sulkowski, Liyun Ni, Joe Llewellyn, Heshaam M Mir, Nika Sajed, Luisa M Stamm, Robert H Hyland, John McNally, Diana M Brainard, Ira Jacobson, Stefan Zeuzem, Marc Bourlière, Graham Foster, Nezam Afdhal, Gregory J Dore
Background: Hepatitis C virus (HCV) direct-acting antiviral therapy is effective among people receiving opioid substitution therapy (OST), but studies are limited by small numbers of nongenotype 1 (GT1) patients. The aim of this study was to evaluate the treatment completion, adherence, SVR12, and safety of sofosbuvir-based therapies in HCV patients receiving and not receiving OST. Methods: Ten phase 3 studies of sofosbuvir-based regimens included ION (ledipasvir/sofosbuvir ± ribavirin for 8, 12, or 24 weeks in GT1), ASTRAL (sofosbuvir/velpatasvir for 12 weeks in GT1-6), and POLARIS (sofosbuvir/velpatasvir and sofosbuvir/velpatasvir/voxilaprevir in GT1-6)...
February 2018: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/29449263/patterns-of-methadone-maintenance-treatment-provision-in-ontario-policy-success-or-pendulum-excess
#17
Paul Kurdyak, Binu Jacob, Juveria Zaheer, Benedikt Fischer
OBJECTIVE: To describe recent trends and patterns in methadone maintenance treatment (MMT) practice regionally and over time in the province of Ontario. DESIGN: Population-based descriptive study using health administrative data between September 1, 2011, and December 31, 2014. SETTING: Ontario. PARTICIPANTS: All active MMT-prescribing physicians and patients receiving MMT in the study period. MAIN OUTCOME MEASURES: Characteristics of MMT-prescribing physicians, including age, sex, specialty type, practice region, and practice volume; characteristics of patients receiving MMT, including age, sex, neighbourhood income, and region of residence...
February 2018: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/29447584/a-longitudinal-qualitative-analysis-of-the-lived-experience-of-the-recovery-process-in-opioid-dependent-patients-post-detoxification
#18
J H Ivers, F Larkan, J Barry
The aim of the study was to gain an in-depth understanding of opioid-dependent patients' lived experiences post-detoxification. METHOD: The study employed a naturalistic, observational longitudinal design, involving baseline screening and tracking of patients post-detoxification, with follow-up interviews at three, six, and nine months to observe specific processes of interest. This in-depth investigation of patients at four points was new within an Irish context and novel throughout the literature...
February 15, 2018: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/29447177/physician-prescribing-of-opioid-agonist-treatments-in-provincial-correctional-facilities-in-ontario-canada-a-survey
#19
Fiona G Kouyoumdjian, Alexandra Patel, Matthew J To, Lori Kiefer, Leonora Regenstreif
BACKGROUND: Substance use and substance use disorders are common in people who experience detention or incarceration in Canada, and opioid agonist treatment (OAT) may reduce the harms associated with substance use disorders. We aimed to define current physician practice in provincial correctional facilities in Ontario with respect to prescribing OAT and to identify potential barriers and facilitators to prescribing OAT. METHODS: We invited all physicians practicing in the 26 provincial correctional facilities for adults in Ontario to participate in an online survey...
2018: PloS One
https://www.readbyqxmd.com/read/29446063/direct-and-indirect-healthcare-resource-utilization-and-costs-among-migraine-patients-in-the-united-states
#20
Machaon Bonafede, Sandhya Sapra, Neel Shah, Stewart Tepper, Katherine Cappell, Pooja Desai
OBJECTIVE: The goal of this analysis was to provide a contemporary estimate of the burden of migraine, incorporating both direct and indirect costs, by comparing the costs of migraine patients to a matched group of patients without migraine in a large, nationally representative sample of commercially insured patients in the United States. BACKGROUND: Previous studies have shown that the economic burden of migraine in the United States is substantial for payers, patients, and employers...
February 15, 2018: Headache
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