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https://www.readbyqxmd.com/read/28636472/benign-tumors-of-the-parotid-gland-a-retrospective-study-of-339-patients
#1
Marie Quiriny, Cécile Dekeyser, Michel Moreau, Antoine Digonnet, Esther Willemse, Laurent Vanbel, Guy Andry
AIM: Among 339 patients operated for benign tumor of the parotid gland: the recurrences and the postoperative complications rates were compared WITH those published in literature. MATERIALS AND METHODS: About 339 patients operated: 274 primarily and 65 for recurrence or residual tumor. VARIABLES: sex, age, surgical techniques, pre- or postoperative radiotherapy, histology, size and localization of the tumors, disease free intervals, recurrences and postoperative complications...
February 10, 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/28635239/-an-analysis-of-incidence-trends-and-characteristics-of-soft-tissue-sarcoma-in-beijing-1999-2013
#2
L Yang, Z W Fang, Z F Fan, N Wang, Y N Yuan, H C Li, S Liu
Objective: To analyze the incidence trends and to describe the characteristics of soft tissue sarcoma (STS) among residents in Beijing from 1999 to 2013. Methods: Medical information of the cases diagnosed as STS(ICD10: C47&C49) from 1999 to 2013 in Beijing was extracted from the population-based database of Beijing Cancer Registry.Crude incidence rate, age-standardized incidence rates to Chinese population (ASRC)and the world population(ASRW) were calculated. The characteristics of the STS cases in different gender and age groups from urban and rural areas were respectively analyzed...
June 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28634639/the-curious-case-of-achromobacter-eurydice-a-gram-variable-pleomorphic-bacterium-associated-with-european-foulbrood-disease-in-honeybees
#3
REVIEW
Silvio Erler, Oleg Lewkowski, Anja Poehlein, Eva Forsgren
Honeybees are prone to parasite and pathogen infestations/infections due to their social colony life. Bacterial pathogens in particular lead to destructive infections of the brood. European foulbrood is caused by the bacterium Melissococcus plutonius in combination with several other Gram-positive bacteria (Achromobacter eurydice, Bacillus pumilus, Brevibacillus laterosporus, Enterococcus faecalis, Paenibacillus alvei, Paenibacillus dendritiformis) involved as secondary invaders following the initial infection...
June 21, 2017: Microbial Ecology
https://www.readbyqxmd.com/read/28631686/-laryngeal-pleomorphic-adenoma
#4
D M Mustafaev
Pleomorphic adenomas are the most widespread epithelial tumours originating from the salivary glands. In almost 90% of the cases, they are localized in the parotid salivary glands. Pleomorphic adenomas only rarely affect the larynx. To the best of our knowledge, as many as 27 cases of laryngeal pleomorphic adenoma have thus far been described in the special literature. The present article was designed to report a case of pleomorphic adenoma in the larynx of a 76 year-old male patient. The surgical treatment of this condition proved beneficial for the patient whose condition remains uncomplicated by the relapse of the tumour during the 5 year-long postoperative follow-up...
2017: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/28629831/extracapsular-dissection-in-the-parapharyngeal-space-benefits-and-potential-pitfalls
#5
K Mantsopoulos, S Müller, A Agaimy, M Goncalves, M Koch, W Wüst, C Bohr, H Iro
The aim of this study was to investigate the benefits and potential pitfalls of transcervical extracapsular dissection in the treatment of parotid gland tumours in the parapharyngeal space. We retrospectively evaluated the records of all patients with parapharyngeal parotid gland lesions treated between 2000 and 2015 by transcervical extracapsular dissection. Patients having revision operations and patients whose records were not complete were excluded, leaving 49 patients in the study. We found acceptable oncological and functional outcomes throughout...
June 16, 2017: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/28629789/undifferentiated-high-grade-pleomorphic-sarcoma-of-ethmoid-sinus-a-case-report-and-literature-review
#6
Yupeng Zhu, Dapeng Hao, Xiaoyan Tang, Lei Sun
No abstract text is available yet for this article.
June 1, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28628689/aggressive-skin-cancers-occurring-in-patients-treated-with-the-janus-kinase-inhibitor-ruxolitinib
#7
Adam B Blechman, Christine E Cabell, Christine H Weinberger, Anna Duckworth, Justin J Leitenberger, Fiona O Zwald, Mark A Russell
<p>The Food and Drug Administration approved Ruxolitinib in 2011 for the treatment of primary myelofibrosis. Five-year safety data showed a higher incidence of skin cancer in patients treated with Ruxolitinib compared to best available therapy for myelofibrosis. This report presents a series of five patients with history of myelofibrosis treated with Ruxolitinib who subsequently developed numerous skin cancers with aggressive biological behavior. Each patient in this report was treated by a Mohs surgeon affiliated with an academic institution...
May 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28626593/langerhans-cell-sarcoma-a-case-report-demonstrating-morphological-and-immunophenotypical-variability-within-a-single-lesion
#8
Rasika Singh, Charles Edward Keen, Christopher Stone, Patrick Sarsfield
Langerhans cells are antigen presenting dendritic cells and tumours arising from these are rare. The tumours arising from these dendritic cells are divided into two categories according to a WHO classification: Langerhans cell histiocytosis and Langerhans cell sarcoma. It is the degree of atypia and clinical aggressiveness that distinguishes the two subtypes. Langerhans cell sarcoma (LCS) is a neoplastic proliferation of Langerhans cells which can occur in skin, bone marrow, lymph nodes, spleen, liver, and lung...
2017: Case Reports in Pathology
https://www.readbyqxmd.com/read/28626490/soft-tissue-sarcomas-in-the-head-and-neck-25-years-of-experience
#9
Juan Francisco Liuzzi, Maribel Da Cunha, Daniuska Salas, Saul Siso, Esteban Garriga
Sarcomas are infrequent and heterogeneous tumours. They represent 1-2% of all malignant neoplasms in adults and between 4% and 10% of head and neck cancers. METHODS: The research was retrospective, descriptive, and cross-sectional. RESULTS: A study population of 62 patients with a mean age of 44 years was obtained; the most frequent location was the soft tissues of the neck (25.3%) and the mean tumour size was 7.1 cm; the most frequent diagnosis was undifferentiated pleomorphic sarcoma (25...
2017: Ecancermedicalscience
https://www.readbyqxmd.com/read/28625007/the-role-of-insulin-like-growth-factor-i-ii-receptor-on-development-of-pleomorphic-adenoma
#10
Ibrahim Arslan, Erol Keles, I Hanifi Ozercan, Mehmet Tokdemir, Turgut Karlidag, Irfan Kaygusuz, Orkun Eroglu, Koray Yuksel, Sinasi Yalcin
Pleomorphic adenoma is a slow-growing salivary gland tumor frequently arising from the parotid gland. In this study, we investigated the role of the insulin-like growth factor I-II receptor (IGFI-IIR) levels on the development of parotid gland pleomorphic adenomas. The study included 20 males and 20 females who had superficial parotidectomy with a histopathological diagnosis of pleomorphic adenoma in Fırat University Otorhinolaryngology Clinic between 2000 and 2011. The ages of the patients ranged between 20 and 50 years...
June 17, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28623706/primary-inferior-vena-cava-smooth-muscle-tumor-with-diffuse-bizarre-giant-nuclei-and-low-mitotic-rate-a-nomenclatural-conundrum
#11
Runjan Chetty, Sangeetha N Kalimuthu, Hanna-Riikka Heinonen
A male patient with obstructive jaundice was found to have an incidental nodule within the inferior vena cava (IVC), below the level of the renal vein, on abdominal imaging. At the time of the Whipple's procedure for pancreatic adenocarcinoma, the IVC mass measuring 3.4×2.7×2.2 cm was also removed. Histologically, the lesion was well circumscribed, composed focally of spindle-shaped cells with cigar-shaped nuclei reminiscent of smooth muscle and a dominant pervasive, pleomorphic, bizarre giant cell component...
June 4, 2017: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://www.readbyqxmd.com/read/28622526/extragastrointestinal-stromal-tumour-of-the-lesser-omentum-a-case-report-and-literature-review
#12
I E Katsoulis, A Tzortzopoulou, P Tziakou, N Arnogiannaki, I Kostoglou-Athanassiou, G Lypas, I G Karaitianos
INTRODUCTION: Extragastrointestinal stromal tumours (EGISTs) are very uncommon compared to their gastrointestinal counterparts. Most of them originate from the intestinal mesentery and the omentum. CASE REPORT: A 70 year-old Caucasian woman presented with a bulky abdominal mass which on laparotomy was found to originate from the lesser omentum and was completely resected. Histological examination revealed spindle cells with severe pleomorphism and high mitotic activity...
June 8, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28622181/validation-of-a-mitotic-index-cutoff-as-a-prognostic-marker-in-undifferentiated-uterine-sarcomas
#13
Elin Hardell, Sofia Josefson, Mehran Ghaderi, Tone Skeie-Jensen, Sofia Westbom-Fremer, Elizabeth H Cheek, Debra Bell, Jonas Selling, John K Schoolmeester, Anna Måsbäck, Ben Davidson, Joseph W Carlson
Undifferentiated uterine sarcomas (UUS) are a heterogenous group of high-grade mesenchymal tumors. Although these tumors are highly aggressive, a subset of patients may experience long-term survival. These tumors have previously been divided morphologically into uniform and pleomorphic types. A previous study demonstrated that a mitotic index cutoff of 25 mitoses/10 high-power fields (corresponding to 11.16 mitotic figures/mm) could successfully divide tumors into 2 prognostic groups with significantly different overall survival...
June 15, 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28619387/evaluation-of-ameliorative-ability-of-silibinin-against-zidovudine-and-isoniazid-induced-hepatotoxicity-and-hyperlipidaemia-in-rats-role-of-silibinin-in-phase-i-and-ii-drug-metabolism
#14
Raghu Ramanathan, Karthikeyan Sivanesan
HIV/AIDS patients have suppressed immune system, making them vulnerable to many opportunistic infections including tuberculosis (TB). The patients who are co-infected with TB undergo combined regimens with anti-retroviral drugs such as zidovudine (AZT) and anti-tubercular drug such as isoniazid (INH) for therapy leading to hepatotoxicty. Silibinin (SBN), extracted from Silybum marianum commonly called as "Milk thistle" is used against several drugs-induced hepatotoxicity. The present study evaluates the ameliorative effect of SBN against AZT alone, INH alone, and INH + AZT-induced toxic insults to liver of rats...
June 13, 2017: Chemico-biological Interactions
https://www.readbyqxmd.com/read/28616281/clinicopathological-factors-influenced-the-prognosis-of-surgically-resected-pulmonary-pleomorphic-carcinoma
#15
Katsuhiro Okuda, Risa Oda, Ayumi Suzuki, Tadashi Sakane, Osamu Kawano, Hiroshi Haneda, Satoru Moriyama, Ryoichi Nakanishi
BACKGROUND: Pulmonary pleomorphic carcinoma has made an unfavorable prognosis because of its properties of resisting radiation and chemotherapy, and its aggressive growth. The correlation between clinicopathological factors and prognosis about pulmonary pleomorphic carcinoma patients who received its surgical resection has not been clearly identified. METHODS: We retrospectively investigated the clinical records of 24 pulmonary pleomorphic carcinoma patients who had a surgical resection from January 2004 to December 2013 at our institute...
May 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28614235/pulmonary-spindle-cell-carcinoma-with-unusual-morphology-a-rare-case-report-and-review-of-the-literature
#16
Dian-Jun Qi, Bing Liu, Liang Feng, Lin Zhao, Ping Yan, Jiang Du, Qing-Fu Zhang
RATIONALE: Pulmonary spindle cell carcinoma (PSCC) is a highly malignant carcinoma that often exhibits the histopathological characteristic of cell pleomorphism. PATIENT CONCERNS: Here, we report a PSCC case in a 59-year-old woman with multiple metastases. The pathological manifestation of this case did not show high-grade pleomorphism or atypia, and was easily mimicked by other borderline or low-grade malignant tumors such as an inflammatory myofibroblastic tumor (IMT)...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28612331/isolation-and-characterization-of-trophoblasts-from-enzymatic-explants-of-human-term-placenta
#17
Tamara D Kolokoltsova, Irina N Saburina, Irina M Zurina, Anastasia A Gorkun, Nastasia V Kosheleva, Vadim S Repin, Rimma A Poltavtseva, Gennady T Sukhikh
In the present study, we describe a new method of isolation and culture of human villous and extravillous trophoblasts from term placenta. The cultivation of trypsinized placental villous tissue explants, followed by the isolation of cells from outgrowth islets allows for obtaining a cytotrophoblast subpopulation that is free from contamination by other cell types. Compared to other methods, our protocol is mild, simple and effective, does not request costly reagents and provides isolation of the mononuclear cytotrophoblast cell populations free from contamination by other types of placental cells...
June 13, 2017: Human Cell
https://www.readbyqxmd.com/read/28612330/endothelial-cell-changes-after-photorefractive-keratectomy-with-graded-usage-of-mitomycin-c
#18
Hamid Gharaee, Siamak Zarei-Ghanavati, Reza Alizadeh, Mojtaba Abrishami
PURPOSE: To compare differences in the endothelial cells before and after photorefractive keratectomy (PRK) for myopia with refractive error graded mitomycin C (MMC) application. METHODS: In a prospective randomized clinical trial, forty-eight myopic patients referred to Khatam-al-Anbia Eye Hospital, Mashhad, Iran, for PRK. Patients were treated with PRK by a Bausch and Lomb Technolas 217z excimer laser (Bausch and Lomb, Rochester, NY). MMC was applied after PRK 5 s for each diopter of spherical equivalent myopic refractive error corrected...
June 13, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28612315/the-differential-diagnosis-of-parotid-gland-tumors-with-high-resolution-ultrasound-in-otolaryngological-practice
#19
Anna Rzepakowska, Ewa Osuch-Wójcikiewicz, Maria Sobol, Raul Cruz, Ewelina Sielska-Badurek, Kazimierz Niemczyk
The aim of the study is to define the utility of ultrasound (US) in differentiating benign from malignant parotid tumors as well as pleomorphic adenomas (PA) from monomorphic adenoma (MA). Seventy-two consecutive parotid gland tumors were analysed with high-resolution ultrasonography (12 MHz) with color Doppler imagining. The histopathological diagnosis was confirmed after parotidectomy for each lesion. The sensitivity, specificity, accuracy, positive predictive value (PPV), and negative predictive value (NPV) for the US were established...
June 13, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28612228/pleomorphic-lobular-carcinoma-in-situ-of-the-breast-a-single-institution-experience-with-clinical-follow-up-and-centralized-pathology-review
#20
Marina De Brot, Starr Koslow Mautner, Shirin Muhsen, Victor P Andrade, Anita Mamtani, Melissa Murray, Dilip Giri, Rita A Sakr, Edi Brogi, Tari A King
PURPOSE: The natural history of pleomorphic lobular carcinoma in situ (PLCIS) remains largely unknown. METHODS: A pathology database search (1995-2012) was performed to identify patients diagnosed with an LCIS variant. Patients with synchronous breast cancer and/or no evidence of pleomorphism were excluded. Original slides were re-evaluated by three pathologists to identify a consensus cohort of PLCIS. Borderline lesions with focal atypia were classified as LCIS with pleomorphic features (LCIS-PF)...
June 13, 2017: Breast Cancer Research and Treatment
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