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https://www.readbyqxmd.com/read/28937829/nonlinearity-coherence-and-complexity-biophysical-aspects-related-to-health-and-disease
#1
Alberto Foletti, Larissa Brizhik
Biological organisms are complex open dissipative systems whose dynamical stability is sustained due to the exchange of matter, energy and information. Dynamical stability occurs through a number of mechanisms that sustain efficient adaptive dynamics. Such properties of living matter can be the consequence of a self-consistent state of matter and electromagnetic field (EMF). Based on the soliton model of charge transport in redox processes, we describe a possible mechanism of the origin of endogenous EMF and coherence...
September 22, 2017: Electromagnetic Biology and Medicine
https://www.readbyqxmd.com/read/28937317/what-is-important-to-patients-in-palliative-care-a-scoping-review-of-the-patient-s-perspective
#2
Helen von Post, Petra Wagman
BACKGROUND: The research conducted in palliative care is often medically oriented. There are few studies clarifying the patient's preferences, priorities and desires in palliative care. The occupational therapy research conducted mostly concerns occupational therapy interventions based on the profession's experiences. Further knowledge is needed regarding what patients in palliative care want to prioritize. AIM: The aim was to describe what patients in palliative care describe as important at the end of life...
September 22, 2017: Scandinavian Journal of Occupational Therapy
https://www.readbyqxmd.com/read/28936927/-you-ve-gotta-be-that-tough-crust-exterior-man-depression-and-suicide-in-rural-based-men
#3
Genevieve Creighton, John Oliffe, John Ogrodniczuk, Blye Frank
Suicide rates in Canada are highest among rural men. Drawing on photovoice interviews with 13 women and two men living in a small rural Canadian town who lost a man to suicide, we inductively derived three themes to describe how contextual factors influence rural men's experiences of depression and responses to suicidal thoughts: (a) hiding depression and its cause, (b) manly self-medicating, and (c) mobilizing prevention. Further discussed is how gender relations and ideals of masculinity within rural milieu can inhibit men's acknowledgment of and help seeking for mental illness issues...
October 2017: Qualitative Health Research
https://www.readbyqxmd.com/read/28936883/taking-back-a-little-of-what-you-have-lost-the-meaning-of-using-an-environmental-control-system-ecs-for-people-with-high-cervical-spinal-cord-injury
#4
Michele Verdonck, Maeve Nolan, Gill Chard
PURPOSE: Assistive technologies have deep and personal meanings for people with disabilities. This study sought to provide an in-depth exploration of the subjective meaning of Environmental Control System (ECS) use for people with high cervical spinal cord injury. MATERIALS AND METHOD: Interpretative Phenomenological Analysis (IPA) was used to explore the personal meaning of ECS. In-depth interviews with five participants were analyzed according to recommended IPA guidelines to produce a rich phenomenological account of lived experience...
September 22, 2017: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/28936685/living-donor-liver-transplantation-in-south-asia-single-center-experience-on-intermediate-term-outcomes
#5
Faisal S Dar, Abu Bakar H Bhatti, Ammal I Qureshi, Nusrat Y Khan, Zahaan Eswani, Haseeb H Zia, Eitzaz U Khan, Nasir A Khan, Atif Rana, Najmul H Shah, Mohammad Salih, Rashid Nazer
BACKGROUND: There is paucity of data on intermediate-term post liver transplant outcomes from South Asia. The objective of this study was to determine survival outcomes in patients who underwent living donor liver transplantation (LDLT) in a busy liver transplant center in Pakistan. METHODS: This study was a review of patients who underwent LDLT between 2012 and 2016. A total of 321 patients were included in this study. Early (within 90 days) and late (>90 days) morbidity and mortality was assessed...
September 21, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28935852/single-center-experience-in-pre-transplant-hepatitis-c-virus-hcv-treatment-among-living-donor-liver-transplant-candidates-bridging-the-direct-acting-antivirals-daa
#6
Ashwini M Niranjan-Azadi, Gokhan Kabacam, Christine M Durand, Saad Anjum, Behnam Saberi, Nabil N Dagher, Benjamin Philosophe, Ahmet Gurakar
BACKGROUND Treatment with DAAs before deceased donor liver transplantation has been shown to be an effective strategy to prevent post-transplant HCV recurrence, with a 95% cure-rate among individuals who achieve undetectable HCV VL for ≥30 days pre- transplant. This strategy has not been evaluated in LDLT. MATERIAL AND METHODS We evaluated outcomes in LDLT recipients treated with DAAs pre-transplant and bridged with 4 weeks of post-transplant SOF. All cases of LDLT at Johns Hopkins (1/1/2014-3/1/15) were retrospectively reviewed...
September 22, 2017: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/28934767/family-planning-unmet-need-and-access-among-itaukei-women-in-new-zealand-and-fiji
#7
Radilaite Cammock, Peter Herbison, Sarah Lovell, Patricia Priest
AIM: The aim of the study was to identify unmet need and family planning access among indigenous Fijian or iTaukei women living in New Zealand and Fiji. METHOD: A cross-sectional survey was undertaken between 2012-2013 in five major cities in New Zealand: Auckland, Hamilton, Wellington, Christchurch and Dunedin; and in three suburbs in Fiji. Women who did not want any (more) children but were not using any form of contraception were defined as having an unmet need...
September 22, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/28934765/qualitative-study-the-experience-and-impact-of-living-with-behcet-s-syndrome
#8
Vicky Tai, Karen Lindsay, Joanne L Sims, Fiona M McQueen
AIM: Behcet's syndrome is a rare chronic multisystemic vasculitis of unknown aetiology, is unpredictable and can cause life-threatening complications. This qualitative study aims to explore the experiences of patients living with Behcet's syndrome in New Zealand. METHODS: Eight English-speaking patients participated in in-depth semi-structured interviews about their experiences of living with Behcet's syndrome. Interviews were recorded and transcribed. Data were analysed using a general inductive thematic approach...
September 22, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/28934251/new-experimental-model-for-single-liver-lobe-hyperthermia-in-small-animals-using-non-directional-microwaves
#9
Ionuț Tudorancea, Vlad Porumb, Alexandru Trandabăţ, Decebal Neaga, Bogdan Tamba, Radu Iliescu, Gabriel M Dimofte
PURPOSE: Our aim was to develop a new experimental model for in vivo hyperthermia using non-directional microwaves, applicable to small experimental animals. We present an affordable approach for targeted microwave heat delivery to an isolated liver lobe in rat, which allows rapid, precise and stable tissue temperature control. MATERIALS AND METHODS: A new experimental model is proposed. We used a commercial available magnetron generating 2450 MHz, with 4.4V and 14A in the filament and 4500V anodic voltage...
2017: PloS One
https://www.readbyqxmd.com/read/28934106/biosensor-technology-reveals-the-disruption-of-the-endothelial-barrier-function-and-the-subsequent-death-of-blood-brain-barrier-endothelial-cells-to-sodium-azide-and-its-gaseous-products
#10
Dan T Kho, Rebecca H Johnson, Simon J O'Carroll, Catherine E Angel, E Scott Graham
Herein we demonstrate the sensitive nature of human blood-brain barrier (BBB) endothelial cells to sodium azide and its gaseous product. Sodium azide is known to be acutely cytotoxic at low millimolar concentrations, hence its use as a biological preservative (e.g., in antibodies). Loss of barrier integrity was noticed in experiments using Electric Cell-substrate Impedance Sensing (ECIS) biosensor technology, to measure endothelial barrier integrity continuously in real-time. Initially the effect of sodium azide was observed as an artefact where it was present in antibodies being employed in neutralisation experiments...
September 21, 2017: Biosensors
https://www.readbyqxmd.com/read/28933993/gradual-physical-decline-characterises-the-illness-trajectories-of-care-home-residents
#11
Anne M Finucane, Barbara Stevenson, Scott A Murray
BACKGROUND: Three archetypal trajectories of physical decline have been identified: a short period of rapid decline; long-term limitations with intermittent acute periods; and a prolonged gradual decline. An understanding of illness trajectories can help clarify the evolving needs of people with progressive conditions, and inform the development of palliative care services to meet their needs. Many frail older people live and die in care homes; the present study is the first to explore the illness trajectories of residents in care home settings...
September 2, 2017: International Journal of Palliative Nursing
https://www.readbyqxmd.com/read/28933947/on-the-safety-of-machine-learning-cyber-physical-systems-decision-sciences-and-data-products
#12
Kush R Varshney, Homa Alemzadeh
Machine learning algorithms increasingly influence our decisions and interact with us in all parts of our daily lives. Therefore, just as we consider the safety of power plants, highways, and a variety of other engineered socio-technical systems, we must also take into account the safety of systems involving machine learning. Heretofore, the definition of safety has not been formalized in a machine learning context. In this article, we do so by defining machine learning safety in terms of risk, epistemic uncertainty, and the harm incurred by unwanted outcomes...
September 2017: Big Data
https://www.readbyqxmd.com/read/28933640/the-impact-of-antithrombin-deficiency-on-women-s-reproductive-health-experiences-and-healthcare-decision-making
#13
Ariela L Marshall, Juliana Perez Botero, Aneel A Ashrani, Rajiv K Pruthi, John A Heit, Ashish Chintakuntlawar, Jennifer C Guenther, Mrinal M Patnaik
BACKGROUND: Women with inherited antithrombin (AT) deficiency are at high risk for venous thromboembolism (VTE), especially during times of estrogen exposure, but little is known about patient-oriented reproductive decision-making in this population. MATERIALS AND METHODS: Provider-administered survey of women with AT deficiency. Participants were asked to discuss their diagnosis of AT deficiency and questioned about (1) contraception, (2) pregnancies, and (3) menorrhagia, and the impact of their AT deficiency on each reproductive health experience...
September 21, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28933360/detection-of-alphacoronavirus-vrna-in-the-feces-of-brazilian-free-tailed-bats-tadarida-brasiliensis-from-a-colony-in-florida-usa
#14
Tania S Bonny, John P Driver, Taylor Paisie, Marco Salemi, John Glenn Morris, Lisa A Shender, Lisa Smith, Carolyn Enloe, Kevin Oxenrider, Jeffery A Gore, Julia C Loeb, Chang-Yu Wu, John A Lednicky
Bats are natural reservoirs of coronaviruses and other viruses with zoonotic potential. Florida has indigenous non-migratory populations of Brazilian free-tailed bats (Tadarida brasiliensis) that mostly roost in colonies in artificial structures. Unlike their counterparts in Brazil and Mexico, the viruses harbored by the Florida bats have been underexplored. We report the detection of an alphacoronavirus RNA-dependent RNA polymerase (RdRp) gene sequence in the feces of two of 19 different T. brasiliensis that were capture/release bats that had been evaluated for overall health...
February 27, 2017: Diseases (Basel)
https://www.readbyqxmd.com/read/28933037/effects-of-strain-sex-and-season-on-body-weight-development-of-cane-rat-thryonomys-swinderianus-in-the-humid-tropics
#15
Oluwatosin M A Jesuyon
The effects of strain (G), sex (H), and season (S) on live weight development of cane rats (Thryonomys swinderianus) reared in captive system were investigated during the dry (35.95 °C) and wet seasons (25.81 °C) from February to August of a tropical environment. The field experiment took place at the University of Ibadan. Seventy-nine cane rats spreading among three genotypes (Bamidele, FRIN, and Lawole) of different age and body weight groups were randomly distributed into cages using randomized complete block design in factorial...
September 20, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28932766/poststroke-trajectories-the-process-of-recovery-over-the-longer-term-following-stroke
#16
Rebecca J Hawkins, Adam Jowett, Mary Godfrey, Kirste Mellish, John Young, Amanda Farrin, Ivana Holloway, Jenny Hewison, Anne Forster
We adopted a grounded theory approach to explore the process of recovery experienced by stroke survivors over the longer term who were living in the community in the United Kingdom, and the interacting factors that are understood to have shaped their recovery trajectories. We used a combination of qualitative methods. From the accounts of 22 purposively sampled stroke survivors, four different recovery trajectories were evident: (a) meaningful recovery, (b) cycles of recovery and decline, (c) ongoing disruption, (d) gradual, ongoing decline...
January 2017: Global Qualitative Nursing Research
https://www.readbyqxmd.com/read/28932574/lung-allocation
#17
REVIEW
Jens Gottlieb
Shortage of donor lungs in most western countries and broadening of indications for lung transplantation (LTx) has led increased waiting list mortality in the past. Usually donor lungs and recipients are matched by size as measured by total lung capacity and blood type in first order. In some countries regional allocation comes first, in other countries a national wait list exists and some nations are organized in supranational allocation systems. Organ distribution should respect the ethical principles of equity, justice, beneficence and utility...
August 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28932172/estimating-the-contribution-of-mortality-selection-to-the-east-west-german-mortality-convergence
#18
Tobias C Vogt, Trifon I Missov
BACKGROUND: Before German reunification, old-age mortality was considerably higher in East Germany than West Germany but converged quickly afterward. Previous studies attributed this rapid catch-up to improved living conditions. We add to this discussion by quantifying for the first time the impact of mortality selection. METHODS: We use a gamma-Gompertz mortality model to estimate the contribution of selection to the East-West German mortality convergence before and after reunification...
2017: Population Health Metrics
https://www.readbyqxmd.com/read/28931738/biological-and-statistical-processes-jointly-drive-population-aggregation-using-host-parasite-interactions-to-understand-taylor-s-power-law
#19
Pieter T J Johnson, Mark Q Wilber
The macroecological pattern known as Taylor's power law (TPL) represents the pervasive tendency of the variance in population density to increase as a power function of the mean. Despite empirical illustrations in systems ranging from viruses to vertebrates, the biological significance of this relationship continues to be debated. Here we combined collection of a unique dataset involving 11 987 amphibian hosts and 332 684 trematode parasites with experimental measurements of core epidemiological outcomes to explicitly test the contributions of hypothesized biological processes in driving aggregation...
September 27, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28931737/changes-in-predator-exposure-but-not-in-diet-induce-phenotypic-plasticity-in-scorpion-venom
#20
Alex N Gangur, Michael Smout, Michael J Liddell, Jamie E Seymour, David Wilson, Tobin D Northfield
Animals embedded between trophic levels must simultaneously balance pressures to deter predators and acquire resources. Venomous animals may use venom toxins to mediate both pressures, and thus changes in this balance may alter the composition of venoms. Basic theory suggests that greater exposure to a predator should induce a larger proportion of defensive venom components relative to offensive venom components, while increases in arms races with prey will elicit the reverse. Alternatively, reducing the need for venom expenditure for food acquisition, for example because of an increase in scavenging, may reduce the production of offensive venom components...
September 27, 2017: Proceedings. Biological Sciences
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