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Down syndrome AND exercise

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https://www.readbyqxmd.com/read/27623609/how-do-adults-with-down-syndrome-perceive-physical-activity
#1
Adam Love, Stamatis Agiovlasitis
Adults with Down syndrome (DS) tend to have low physical activity levels, which may relate to how they perceive participation in physical activities. The current study entailed interviews with 30 adults with DS (age 18-71 yr, 18 women) to examine how they perceived physical activity, exercise, and sport. Through qualitative analysis informed by grounded theory, the investigators found that adults with DS have positive perceptions of physical activity that center on enjoyment. Three facets of enjoyment were identified: interaction, achievement, and process...
July 2016: Adapted Physical Activity Quarterly: APAQ
https://www.readbyqxmd.com/read/27448331/overweight-and-obesity-in-children-and-adolescents-with-down-syndrome-prevalence-determinants-consequences-and-interventions-a-literature-review
#2
REVIEW
Fabio Bertapelli, Ken Pitetti, Stamatis Agiovlasitis, Gil Guerra-Junior
BACKGROUND: Children with Down syndrome (DS) are more likely to be overweight or obese than the general population of youth without DS. AIMS: To review the prevalence of overweight and obesity and their determinants in youth with DS. The health consequences and the effectiveness of interventions were also examined. METHODS AND PROCEDURES: A search using MEDLINE, Embase, Web of Science, Scopus, CINAHL, PsycINFO, SPORTDiscus, LILACS, and COCHRANE was conducted...
October 2016: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/27360401/effect-of-vestibular-stimulation-exercises-on-balance-in-children-with-down-syndrome-1482-board-135-june-2-9-00-am-10-30-am
#3
Sarah Sunderman, Kathleen Carter, Stefanie Wooten-Burnett, Jill Jacobi-Vessels
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27345145/epigenomic-changes-associated-with-impaired-norepinephrine-transporter-function-in-postural-tachycardia-syndrome
#4
Abdul Waheed Khan, Susan J Corcoran, Murray Esler, Assam El-Osta
The postural tachycardia syndrome (POTS) is characterised clinically by symptoms of light-headedness, palpitations, fatigue and exercise intolerance occurring with standing and relieved by lying down. Symptoms occur in association with an inappropriate rise in heart rate in the absence of a fall in blood pressure with the assumption of standing. The pathophysiology of POTS is complicated and poorly understood. Plasma norepinephrine (NE) is often elevated in patients with POTS, resulting in consideration of dysfunction of the norepinephrine transporter (NET) encoded by SLC6A2 gene...
June 23, 2016: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/27274430/tibiofemoral-joint-mobilization-in-the-successful-management-of-patellofemoral-pain-syndrome-a-case-report
#5
Justin M Lantz, Alicia J Emerson-Kavchak, John J Mischke, Carol A Courtney
BACKGROUND AND PURPOSE: Patellofemoral pain syndrome (PFPS) is a common source of anterior knee pain. Controversy exists over the exact clinical findings which define PFPS, thus, diagnosis and management can be challenging for clinicians. There is paucity in the literature concerning joint mobilization as treatment for PFPS, particularly at the tibiofemoral joint, as standard management is currently focused on therapeutic exercise, orthotics, bracing and taping. Therefore, the purpose of this case report is to describe the effects of tibiofemoral joint mobilization in the successful treatment of an individual with chronic PFPS as it relates to pain, function and central processing of pain...
June 2016: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/27165540/cardiac-autonomic-modulation-and-blood-pressure-responses-to-isometric-handgrip-and-submaximal-cycling-exercise-in-individuals-with-down-syndrome
#6
Kanokwan Bunsawat, Tracy Baynard
PURPOSE: Individuals with Down syndrome (DS) exhibit autonomic dysfunction, manifested as attenuated heart rate (HR) and blood pressure (BP) responses to sympathoexcitation. Whether a subgroup of individuals with DS with a normal HR response would have normal autonomic responses to sympathoexcitation remains unclear. METHODS: We compared autonomic modulation using HR variability (HRV) and BP responses in individuals with and without DS (controls) matched for the HR change to isometric handgrip (HG) (10 DS, 8 controls) and submaximal cycling exercise (CE) (9 DS, 9 controls)...
August 2016: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/27106806/nuclear-receptors-and-ampk-can-exercise-mimetics-cure-diabetes
#7
REVIEW
Christopher E Wall, Ruth T Yu, Anne R Atkins, Michael Downes, Ronald M Evans
Endurance exercise can lead to systemic improvements in insulin sensitivity and metabolic homeostasis, and is an effective approach to combat metabolic diseases. Pharmacological compounds that recapitulate the beneficial effects of exercise, also known as 'exercise mimetics', have the potential to improve disease symptoms of metabolic syndrome. These drugs, which can increase energy expenditure, suppress hepatic gluconeogenesis, and induce insulin sensitization, have accordingly been highly scrutinized for their utility in treating metabolic diseases including diabetes...
July 2016: Journal of Molecular Endocrinology
https://www.readbyqxmd.com/read/27099763/effect-of-dual-pulmonary-vasodilator-therapy-in-pulmonary-arterial-hypertension-associated-with-congenital-heart-disease-a-retrospective-analysis
#8
Oliver Monfredi, Elliot Heward, Linda Griffiths, Robin Condliffe, Vaikom S Mahadevan
BACKGROUND: Patients with pulmonary arterial hypertension (PAH) are managed according to evidence-based treatment guidelines. METHODS AND RESULTS: In this single-centre retrospective analysis, we examined outcomes of patients with PAH caused by congenital heart disease (PAH-CHD) with respect to exercise capacity and survival of adults treated with either bosentan or sildenafil monotherapy or bosentan-sildenafil dual therapy between January 2007 and January 2014...
2016: Open Heart
https://www.readbyqxmd.com/read/27018305/the-effects-of-assisted-cycling-therapy-act-and-voluntary-cycling-on-reaction-time-and-measures-of-executive-function-in-adolescents-with-down-syndrome
#9
S D R Ringenbach, S D Holzapfel, G M Mulvey, A Jimenez, A Benson, M Richter
BACKGROUND: Reports of positive effects of aerobic exercise on cognitive function in persons with Down syndrome are extremely limited. However, a novel exercise intervention, termed assisted cycling therapy (ACT), has resulted in acutely improved cognitive planning ability and reaction times as well as improved cognitive planning after 8 weeks of ACT in adolescents and young adults with Down syndrome. Here, we report the effects of 8 weeks of ACT on reaction time, set-shifting, inhibition and language fluency in adolescents with Down syndrome...
March 28, 2016: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/26985205/effect-of-cardiac-rehabilitation-program-on-heart-rate-recovery-in-coronary-heart-disease
#10
Leila Mahdavi Anari, Mahdieh Ghanbari-Firoozabadi, Zahra Ansari, Mahmoud Emami, Mohammadreza Vafaii Nasab, Mahdieh Nemaiande, Fatemeh Boostany, Mohamadreza Neishaboury
BACKGROUND: It has been suggested that the autonomic system function and the metabolic syndrome can significantly affect patients' survival. The aim of the current study was to investigate the impact of the cardiac rehabilitation program on the autonomic system balance in patients with coronary artery disease. METHODS: Patients with a previous diagnosis of coronary artery disease who were referred to the Cardiovascular Rehabilitation Center of Afshar Hospital (Yazd, Iran) between March and November 2011 were enrolled...
October 27, 2015: Journal of Tehran Heart Center
https://www.readbyqxmd.com/read/26923820/dose-response-relationship-between-intensity-of-exercise-and-cognitive-performance-in-individuals-with-down-syndrome-a-preliminary-study
#11
C-C J J Chen, S D R Ringenbach
BACKGROUND: Cognitive performance has been shown to be relevant to the early onset of Alzheimer's disease in individuals with Down syndrome. This study was aimed at investigating the dose-response relationship between acute exercise intensity and cognitive performance in this population. METHODS: In the current study, we measured information processing speed and two aspects of executive function (i.e. attention shifting and inhibitory control). Participants were assigned to high-intensity exercise (i...
June 2016: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/26872560/exercise-the-lifelong-supplement-for-healthy-ageing-and-slowing-down-the-onset-of-frailty
#12
Jose Viña, Leocadio Rodriguez-Mañas, Andrea Salvador-Pascual, Francisco José Tarazona-Santabalbina, Mari Carmen Gomez-Cabrera
The beneficial effects of exercise have been well recognized for over half a century. Dr Jeremy Morris's pioneering studies in the fifties showed a striking difference in cardiovascular disease between the drivers and conductors on the double-decker buses in London. These studies sparked off a vast amount of research on the effects of exercise in health, and the general consensus is that exercise contributes to improved outcomes and treatment for several diseases including osteoporosis, diabetes, depression and atherosclerosis...
April 15, 2016: Journal of Physiology
https://www.readbyqxmd.com/read/26805768/effect-of-continuous-aerobic-vs-interval-training-on-selected-anthropometrical-physiological-and-functional-parameters-of-adults-with-down-syndrome
#13
P H Boer, S J Moss
BACKGROUND: A large percentage of adults with Down syndrome (DS) are overweight and have extremely low aerobic capacities compared with the general population and persons with intellectual disability without DS. Previous aerobic training intervention studies showed limited potential to significantly ameliorate anthropometrical and cardiovascular variables. The primary purpose of this study was to determine the effect of continuous aerobic training (CAT) vs. interval training (IT) on selected anthropometrical, health, physical and functional parameters of adults with DS...
January 25, 2016: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/26632421/clinical-asthma-phenotypes-in-the-real-world-opportunities-and-challenges
#14
REVIEW
Clementine Bostantzoglou, Vicky Delimpoura, Konstantinos Samitas, Eleftherios Zervas, Frank Kanniess, Mina Gaga
Asthma is a common, chronic and heterogeneous syndrome, affecting people of all ages, all races and both sexes. It may range from mild disease with barely noticeable symptoms, to very severe disease with constant symptoms that greatly hinder the life of the patient. Guidelines issued by various medical societies provide guidance on how to diagnose and manage asthmatic patients. It is now increasingly recognised that asthma management must be individualised, tailored not only to the severity of the disease but to the phenotypic characteristics of each patient...
September 2015: Breathe
https://www.readbyqxmd.com/read/26434558/physical-activity-engagement-in-young-people-with-down-syndrome-investigating-parental-beliefs
#15
Marianna Alesi, Annamaria Pepi
BACKGROUND: Despite the wide documentation of the physical/psychological benefits derived from regular physical activity (PA), high levels of inactivity are reported among people with Down syndrome. This study aims to explore parental beliefs concerning involvement, facilitators/barriers and benefits of PA in young people. METHOD: Semi-structured interviews were conducted with 13 parents of young people with Down syndrome. RESULTS: Three facilitation themes were identified: (i) the support derived from family; (ii) the availability of APA (Adapted Physical Activity) expert instructors and coaches; (iii) the challenging nature of sport activities...
October 5, 2015: Journal of Applied Research in Intellectual Disabilities: JARID
https://www.readbyqxmd.com/read/26304719/widespread-cerebellar-transcriptome-changes-in-ts65dn-down-syndrome-mouse-model-after-lifelong-running
#16
Marius Walus, Elizabeth Kida, Ausma Rabe, Giorgio Albertini, Adam A Golabek
Our previous study showed an improvement in locomotor deficits after voluntary lifelong running in Ts65Dn mice, an animal model for Down syndrome (DS). In the present study, we employed mouse microarrays printed with 55,681 probes in an attempt to identify molecular changes in the cerebellar transcriptome that might contribute to the observed behavioral benefits of voluntary long-term running in Ts65Dn mice. Euploid mice were processed in parallel for comparative purposes in some analyses. We found that running significantly changed the expression of 4,315 genes in the cerebellum of Ts65Dn mice, over five times more than in euploid animals, up-regulating 1,991 and down-regulating 2,324 genes...
January 1, 2016: Behavioural Brain Research
https://www.readbyqxmd.com/read/26131704/blood-pressure-and-hemodynamic-adaptations-after-a-training-program-in-young-individuals-with-down-syndrome
#17
Bruna Barboza Seron, Karla Fabiana Goessler, Everaldo Lambert Modesto, Eloise Werle Almeida, Márcia Greguol
BACKGROUND: Cardiovascular diseases affect people worldwide. Individuals with Down Syndrome (DS) have an up to sixteen-time greater risk of mortality from cardiovascular diseases. OBJECTIVE: To evaluate the effects of aerobic and resistance exercises on blood pressure and hemodynamic variables of young individuals with DS. METHODS: A total of 29 young individuals with DS participated in the study. They were divided into two groups: aerobic training (AT) (n = 14), and resistance training (TR) (n = 15)...
June 2015: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/26126260/a-case-of-paraspinal-muscle-rhabdomyolysis-in-a-22-year-old-male-after-ingesting-a-supplement-containing-higenamine
#18
Jonathan Jeter, Kent J DeZee, Laura Kennedy
Rhabdomyolysis is a painful and potentially life-threatening injury in which muscle breaks down in response to an insult. In this case report, we describe the clinical course of a 22-year-old man who developed paraspinal muscle rhabdomyolysis and possible compartment syndrome in association with strenuous activity and the ingestion of an exercise supplement containing the stimulant higenamine. Although he did not experience any renal damage, he did experience a high level of pain acutely and for the next 4 months...
July 2015: Military Medicine
https://www.readbyqxmd.com/read/26115435/acute-effects-of-a-therapeutic-mobility-device-on-physical-activity-and-heart-rate-in-children-with-down-syndrome
#19
Janet L Hauck, Dale A Ulrich
PURPOSE: The purpose of this feasibility study was to provide an opportunity to increase physical activity (PA) and heart rate (HR) for children with Down syndrome (DS) during unstructured group exercise utilizing a riding device called the Power Pumper®. METHOD: Twenty-four children aged 5 to 7 years old participated in this case-control study, including 12 children with DS and 12 children without DS. Those without DS participated as age-matched controls. A 30-min unstructured PA session utilizing the Power Pumper was provided to both groups on 2 occasions...
2015: Research Quarterly for Exercise and Sport
https://www.readbyqxmd.com/read/26097692/sports-cardiology-lessons-from-the-past-and-perspectives-for-the-future
#20
Roman Leischik
The possibility of myocardial damage as a result of endurance sport has been known about since ancient times. According to a leg-end, a soldier named Pheidippides (more likely Philippides) dropped dead after run-ning from war-torn Marathon to Athens with the news of victory. Millennia later, we do not know whether he was a soldier or a courier, or whether he really ran the entire 240 km from Athens to Sparta and then back from Marathon to Athens. What is clear however, is that his death went down in history as the first documented exercise-related death and provides a tangible starting-point for the discipline of sport cardiology...
2015: F1000Research
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