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Down syndrome AND exercise

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https://www.readbyqxmd.com/read/29343130/a-community-based-exercise-program-to-increase-participation-in-physical-activities-among-youth-with-disability-a-feasibility-study
#1
Nora Shields, Roos van den Bos, Kirsty Buhlert-Smith, Luke Prendergast, Nicholas Taylor
PURPOSE: To evaluate the feasibility of a student-mentored community-based exercise program for youth with disability. METHOD: Nineteen youth (nine female; mean age 18 years) with disability (seven cerebral palsy, six Down syndrome, three spina bifida, two autism spectrum disorder, one spinal cord injury) were recruited. Each participant was matched with a student mentor and exercised twice a week for 12 weeks at their local gymnasium. Five domains of feasibility were assessed: demand, implementation, practicality, limited efficacy testing, and acceptability...
January 17, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29330572/effects-of-whole-body-vibration-on-muscle-strength-bone-mineral-content-and-density-and-balance-and-body-composition-of-children-and-adolescents-with-down-syndrome-a-systematic-review
#2
REVIEW
M B Saquetto, F F Pereira, R S Queiroz, C M da Silva, C S Conceição, M Gomes Neto
The aim of this study is to verify the effects of whole-body vibration (WBV) training on the muscle strength of children and adolescents with Down syndrome. We searched MEDLINE, Cochrane, SciELO, Lilacs and PUBMED databases and included manual searches to identify randomised controlled trials to investigate the effects of WBV on the structure and body function of children and adolescents with Down syndrome. Two reviewers independently selected the studies and performed statistical analysis. In total, five studies with 171 patients that compared WBV with exercise and/or control were included...
January 12, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29321033/environmental-enrichment-intervention-for-rett-syndrome-an-individually-randomised-stepped-wedge-trial
#3
Jenny Downs, Jenny Rodger, Chen Li, Xuesong Tan, Nan Hu, Kingsley Wong, Nicholas de Klerk, Helen Leonard
BACKGROUND: Rett syndrome is caused by a pathogenic mutation in the MECP2 gene with major consequences for motor and cognitive development. One of the effects of impaired MECP2 function is reduced production of Brain Derived Neurotrophic Factor (BDNF), a protein required for normal neuronal development. When housed in an enriched environment, MECP2 null mice improved motor abilities and increased levels of BDNF in the brain. We investigated the effects of environmental enrichment on gross motor skills and blood BDNF levels in girls with Rett syndrome...
January 10, 2018: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/29231277/do-individuals-with-intellectual-disability-have-a-lower-peak-heart-rate-and-maximal-oxygen-uptake
#4
Thessa Irena Maria Hilgenkamp, Tracy Baynard
BACKGROUND: Individuals with intellectual disability (ID) have very low physical activity and low peak oxygen uptake (VO2peak ), potentially explained by physiologically lower peak heart rates (HRpeak ). METHOD: The present authors performed a retrospective analysis of a large data set of individuals with intellectual disability (n = 100), with Down syndrome (DS) (n = 48) and without intellectual disability (n = 224) using multiple linear regression analyses, to determine if individuals with intellectual disability exhibit lower HRpeak and VO2peak than individuals without intellectual disability, controlling for age, sex and body mass index (BMI)...
December 12, 2017: Journal of Applied Research in Intellectual Disabilities: JARID
https://www.readbyqxmd.com/read/29203796/aerobic-exercise-and-a-bdnf-mimetic-therapy-rescue-learning-and-memory-in-a-mouse-model-of-down-syndrome
#5
Martina Parrini, Diego Ghezzi, Gabriele Deidda, Lucian Medrihan, Enrico Castroflorio, Micol Alberti, Pietro Baldelli, Laura Cancedda, Andrea Contestabile
Down syndrome (DS) is caused by the triplication of human chromosome 21 and represents the most frequent genetic cause of intellectual disability. The trisomic Ts65Dn mouse model of DS shows synaptic deficits and reproduces the essential cognitive disabilities of the human syndrome. Aerobic exercise improved various neurophysiological dysfunctions in Ts65Dn mice, including hippocampal synaptic deficits, by promoting synaptogenesis and neurotransmission at glutamatergic terminals. Most importantly, the same intervention also prompted the recovery of hippocampal adult neurogenesis and synaptic plasticity and restored cognitive performance in trisomic mice...
December 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29192799/communication-as-a-human-right-citizenship-politics-and-the-role-of-the-speech-language-pathologist
#6
Declan Murphy, Rena Lyons, Clare Carroll, Mari Caulfield, Gráinne De Paor
According to Article 19 of the Universal Declaration on Human Rights "Everyone has the right to freedom of opinion and expression; this right includes freedom to hold opinions without interference and to seek, receive and impart information and ideas through any media and regardless of frontiers." The purpose of this paper is to elucidate communication as a human right in the life of a young man called Declan who has Down syndrome. This commentary paper is co-written by Declan, his sister who is a speech-language pathologist (SLP) with an advocacy role, his SLP, and academics...
December 1, 2017: International Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/29103914/what-effect-does-regular-exercise-have-on-oxidative-stress-in-people-with-down-syndrome-a-systematic-review-with-meta-analyses
#7
REVIEW
Nora Shields, Jenny Downs, Judy B de Haan, Nicholas F Taylor, Jennifer Torr, Bo Fernhall, Michael Kingsley, George Mnatzaganian, Helen Leonard
OBJECTIVE: What effect does regular exercise have on oxidative stress in people with Down syndrome? DESIGN: Systematic review with meta-analyses. METHODS: A systematic review with meta-analyses was conducted. Six databases were searched from inception until August 2017. Studies where included if participants with Down syndrome (any age) had completed an exercise program of at least 6 weeks duration and at least one biomarker measured the generation or removal of reactive oxidative species...
October 19, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/29056568/anatomic-and-functional-outcomes-of-paramesonephric-remnant-supported-laparoscopic-double-layer-peritoneal-pull-down-vaginoplasty-technique-in-patients-with-mayer-rokitansky-kuster-hauser-syndrome-uncu-modification
#8
Gürkan Uncu, Kemal Özerkan, Barış Ata, Işıl Kasapoğlu, Mehmet Aral Atalay, Adnan Orhan, Kiper Aslan
OBJECTIVE: To describe modifications to the double layer peritoneal pull-down laparoscopic vaginoplasty technique (Davydov operation). To evaluate anatomic and functional outcomes of the new technique named Uncu Modification. DESIGN: Case series. TASK FORCE CLASSIFICATION OF STUDY DESIGN: III SETTING: Tertiary Care University Hospital PATIENTS: Women with Mayer-Rokitansky-Küster Hauser Syndrome (MRKHS) who were operated on between years 2010-2016...
October 19, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28904967/foot-structure-in-boys-with-down-syndrome
#9
Ewa Puszczałowska-Lizis, Krzysztof Nowak, Jarosław Omorczyk, Tadeusz Ambroży, Przemysław Bujas, Leszek Nosiadek
INTRODUCTION AND AIM: Down syndrome (DS) is associated with numerous developmental abnormalities, some of which cause dysfunctions of the posture and the locomotor system. The analysis of selected features of the foot structure in boys with DS versus their peers without developmental disorders is done. MATERIALS AND METHODS: The podoscopic examination was performed on 30 boys with DS aged 14-15 years. A control group consisted of 30 age- and gender-matched peers without DS...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28676038/efficacy-and-safety-of-oral-sildenafil-in-children-with-down-syndrome-and-pulmonary-hypertension
#10
Maurice Beghetti, Andrzej Rudzinski, Min Zhang
BACKGROUND: Despite the increased risk for pulmonary hypertension in children with Down syndrome, the response to treatment with targeted therapies for pulmonary hypertension in these patients is not well characterized. The Sildenafil in Treatment-naive children, Aged 1-17 years, with pulmonary arterial hypertension (STARTS-1) trial was a dose-ranging study of the short-term efficacy and safety of oral sildenafil in children with pulmonary arterial hypertension. We assessed the safety and efficacy of oral sildenafil in children with Down syndrome and pulmonary arterial hypertension...
July 4, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28586511/factors-affecting-dance-exercise-performance-in-students-at-a-special-needs-school
#11
Yukiko Ito, Izumi Hiramoto, Hideya Kodama
BACKGROUND: In Japan, dance exercise has been introduced as a compulsory element of health and physical education, but there is a considerable discrepancy in the levels of performance among students with intellectual disability (ID) at special needs schools. The aim of this study was therefore to identify the factors affecting the performance of dance exercise in students with ID. METHODS: A 4 month dance exercise program was implemented for junior high school students at a special needs school, and the performance of 32 students at 22 sessions was assessed quantitatively according to calorie use during exercise and performance proficiency score...
June 6, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28585394/wii-based-exercise-program-to-improve-physical-fitness-motor-proficiency-and-functional-mobility-in-adults-with-down-syndrome
#12
V Silva, C Campos, A Sá, M Cavadas, J Pinto, P Simões, S Machado, E Murillo-Rodríguez, N Barbosa-Rocha
BACKGROUND: People with Down syndrome (DS) usually display reduced physical fitness (aerobic capacity, muscle strength and abnormal body composition), motor proficiency impairments (balance and postural control) and physical functional limitations. Exergames can be an appealing alternative to enhance exercise engagement and compliance, whilst improving physical fitness and motor function. This study aims to analyse the effects of a Wii-based exercise program on physical fitness, functional mobility and motor proficiency of adults with DS...
August 2017: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/28535762/gait-initiation-and-termination-strategies-in-patients-with-prader-willi-syndrome
#13
Veronica Cimolin, Nicola Cau, Manuela Galli, Cristina Santovito, Graziano Grugni, Paolo Capodaglio
BACKGROUND: Gait Initiation (GI) is a functional task representing one of the first voluntary destabilizing behaviours observed in the development of a locomotor pattern as the whole body centre of mass transitions from a large to a small base of support. Conversely, Gait Termination (GT) consists in the transition from walking to standing which, in everyday life, is a very common movement. Compared to normal walking, it requires higher control of postural stability. For a safe GT, the forward movement of the body has to be slowed down to achieve a stable upright position...
May 23, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28303472/chronic-exertional-compartment-syndrome-in-the-forearm-of-a-collegiate-softball-pitcher
#14
REVIEW
Austin Cole, John L Hiatt, Christopher Arnold, Terry Sites, Ramon Ylanon
BACKGROUND: Chronic exertional compartment syndrome (CECS) is a recognized condition in the lower limb, with many reports in the literature. However, very few instances include CECS of the upper limb. This article presents the case of a collegiate softball pitcher presenting with CECS in her right forearm. To our knowledge, this is the first case report of a softball player with CECS, with only one similar incident in a major league baseball player. PURPOSE: The rarity of this condition normally places it low on the differential diagnosis...
December 2017: Sports Medicine—Open
https://www.readbyqxmd.com/read/28241808/modified-lingguizhugan-decoction-incorporated-with-dietary-restriction-and-exercise-ameliorates-hyperglycemia-hyperlipidemia-and-hypertension-in-a-rat-model-of-the-metabolic-syndrome
#15
Limei Yao, Jingjing Wei, Si Shi, Kunbin Guo, Xiangyu Wang, Qi Wang, Dingsheng Chen, Weirong Li
BACKGROUND: Modified Lingguizhugan Decoction (MLD) came from famous Chinese medicine Linggui Zhugan Decoction. The MLD is used for the treatment of metabolic syndrome in the clinical setting. Our study focuses on the comprehensive treatment of MLD incorporated with dietary restriction and exercise in a rat model of the metabolic syndrome (MS). METHODS: Rats were divided into five groups: control group (Cont), high-fat diet group (HFD), high-fat diet incorporated with dietary restriction group (HFD-DR), exercise incorporated with dietary restriction group (HFD-DR-Ex) and MLD incorporated with dietary restriction and exercise group (HFD-DR-Ex-MLD)...
February 28, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28119223/the-effect-of-exercise-intervention-on-daily-life-activities-and-social-participation-in-individuals-with-down-syndrome-a-systematic-review
#16
REVIEW
J P Hardee, L Fetters
BACKGROUND: Few systematic reviews have looked at the effect of exercise intervention on activities of daily living and social participation in individuals with Down syndrome (DS) across the lifespan. AIMS: To evaluate the research on the effectiveness of exercise intervention on daily life activities and participation in individuals with DS. METHODS AND PROCEDURES: Studies are from six electronic databases (CINHAL, Cochrane, ERIC, PEDro, PubMed, and PsycINFO) from 1987 to 2016...
March 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28116787/effects-of-detraining-on-anthropometry-aerobic-capacity-and-functional-ability-in-adults-with-down-syndrome
#17
P H Boer
BACKGROUND: Structured exercise has shown to improve parameters of functional fitness in adults with Down syndrome (DS). However, few, if any, continue to exercise after exercise intervention studies. Consequently, the purpose of this study was to determine the effects of detraining on anthropometry, aerobic capacity and functional ability of adults with DS. METHODS: In a previous study, forty-two participants either performed 12 weeks of interval training, continuous aerobic training or no training (CON)...
January 24, 2017: Journal of Applied Research in Intellectual Disabilities: JARID
https://www.readbyqxmd.com/read/28103494/factors-associated-with-meeting-physical-activity-guidelines-by-adults-with-intellectual-and-developmental-disabilities
#18
Roger J Stancliffe, Lynda L Anderson
BACKGROUND: Many individuals with intellectual and developmental disabilities (IDD) have sedentary lifestyles. AIMS: (a) compare adults with IDD with the general adult population on adherence to U.S. physical activity (PA) guidelines, and (b) determine what factors predict adherence to PA guidelines by adults with IDD. METHODS: We compared adults with IDD from the 2011-2012 National Core Indicators Adult Consumer Survey (NCI-ACS) with the general U...
March 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/27623609/how-do-adults-with-down-syndrome-perceive-physical-activity
#19
Adam Love, Stamatis Agiovlasitis
Adults with Down syndrome (DS) tend to have low physical activity levels, which may relate to how they perceive participation in physical activities. The current study entailed interviews with 30 adults with DS (age 18-71 yr, 18 women) to examine how they perceived physical activity, exercise, and sport. Through qualitative analysis informed by grounded theory, the investigators found that adults with DS have positive perceptions of physical activity that center on enjoyment. Three facets of enjoyment were identified: interaction, achievement, and process...
July 2016: Adapted Physical Activity Quarterly: APAQ
https://www.readbyqxmd.com/read/27448331/overweight-and-obesity-in-children-and-adolescents-with-down-syndrome-prevalence-determinants-consequences-and-interventions-a-literature-review
#20
REVIEW
Fabio Bertapelli, Ken Pitetti, Stamatis Agiovlasitis, Gil Guerra-Junior
BACKGROUND: Children with Down syndrome (DS) are more likely to be overweight or obese than the general population of youth without DS. AIMS: To review the prevalence of overweight and obesity and their determinants in youth with DS. The health consequences and the effectiveness of interventions were also examined. METHODS AND PROCEDURES: A search using MEDLINE, Embase, Web of Science, Scopus, CINAHL, PsycINFO, SPORTDiscus, LILACS, and COCHRANE was conducted...
October 2016: Research in Developmental Disabilities
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