keyword
https://read.qxmd.com/read/38536607/echocardiographic-estimation-of-right-ventricular-diastolic-stiffness-based-on-pulmonary-regurgitant-velocity-waveform-analysis-in-precapillary-pulmonary-hypertension
#1
JOURNAL ARTICLE
Yui Nagai, Michito Murayama, Sanae Kaga, Hideki Shima, Satonori Tsuneta, Shinobu Yokoyama, Hisao Nishino, Mana Goto, Yukino Suzuki, Yusuke Yanagi, Suguru Ishizaka, Hiroyuki Iwano, Junichi Nakamura, Takahiro Sato, Ichizo Tsujino
Right ventricular (RV) diastolic stiffness is an independent predictor of survival and is strongly associated with disease severity in patients with precapillary pulmonary hypertension (PH). Therefore, a fully validated echocardiographic method for assessing RV diastolic stiffness needs to be established. This study aimed to compare echocardiography-derived RV diastolic stiffness and invasively measured pressure-volume loop-derived RV diastolic stiffness in patients with precapillary PH. We studied 50 consecutive patients with suspected or confirmed precapillary PH who underwent cardiac catheterization, magnetic resonance imaging, and echocardiography within a 1-week interval...
March 27, 2024: International Journal of Cardiovascular Imaging
https://read.qxmd.com/read/38536563/machine-learning-in-risk-prediction-of-continuous-renal-replacement-therapy-after-coronary-artery-bypass-grafting-surgery-in-patients
#2
JOURNAL ARTICLE
Qian Zhang, Peng Zheng, Zhou Hong, Luo Li, Nannan Liu, Zhiping Bian, Xiangjian Chen, Hengfang Wu, Sheng Zhao
OBJECTIVES: This study aimed to develop machine learning models for risk prediction of continuous renal replacement therapy (CRRT) following coronary artery bypass grafting (CABG) surgery in intensive care unit (ICU) patients. METHODS: We extracted CABG patients from the electronic medical record system of the hospital. The endpoint of this study was the requirement for CRRT after CABG surgery. The Boruta method was used for feature selection. Seven machine learning algorithms were developed to train models and validated using 10 fold cross-validation (CV)...
March 27, 2024: Clinical and Experimental Nephrology
https://read.qxmd.com/read/38535432/assessment-of-the-relationship-between-periodontitis-and-cardiac-parameters-in-patients-with-early-chronic-heart-failure-a-cross-sectional-study
#3
JOURNAL ARTICLE
Antina Schulze, Stefan Kwast, Christoph Pökel, Martin Busse
Periodontal disease (PD) is considered a risk factor for cardiovascular events. However, its relationship to chronic heart failure (CHF) is unclear. The aim was to compare cardiac and inflammatory parameters in CHF patients with (PG) versus without periodontitis (NPG). The following parameters were recorded in 58 patients: periodontal screening and recording (PSR), troponin T, NT-proBNP, C-reactive protein (CRP), interleukin-6 (IL-6), blood pressure, heart rate, ejection fraction (EF), ventricular systolic and diastolic function parameters, incremental test, and three questionnaires (Mediterranean Diet Adherence Screener, MEDAS; Oral Health Impact Profile, OHIP-14; Patient Health Questionnaire, PHQ)...
March 18, 2024: Journal of Functional Morphology and Kinesiology
https://read.qxmd.com/read/38535100/metabolic-dysfunction-associated-liver-disease-in-patients-undergoing-coronary-computed-tomography-angiography
#4
JOURNAL ARTICLE
Rares Ilie Orzan, Rares Ioan Gligor, Renata Agoston, Carmen Cionca, Alexandru Zlibut, Raluca Pais, Andrada Seicean, Lucia Agoston-Coldea
In this single-center cross-sectional study on patients undergoing coronary computed tomography angiography (CCTA), we assessed the prognostic significance of metabolic dysfunction associated steatotic liver disease (MASLD), metabolic syndrome (MetS), and CCTA-derived parameters for predicting major adverse cardiovascular events (MACE). Over a mean follow-up of 26.9 months, 2038 patients were analyzed, with 361 (17.7%) experiencing MACE. MASLD was associated with a higher MACE incidence (25.90% vs. 14.71% without MASLD, p < 0...
February 26, 2024: Journal of Cardiovascular Development and Disease
https://read.qxmd.com/read/38535009/cardiac-magnetic-resonance-imaging-based-ischemic-injury-pattern-in-patients-with-acute-myocardial-infarction-sensu-left-ventricular-global-systolic-function
#5
JOURNAL ARTICLE
Lyudmila Salyamova, Valentin Oleynikov, Natalia Donetskaya, Alexander Vdovkin, Angelina Chernova, Irina Avdeeva
The purpose of the study was to identify factors characterizing a decrease in LV global systolic function in patients with ST-segment elevation myocardial infarction (STEMI) after revascularization using cardiac magnetic resonance imaging (MRI)-based ischemic injury pattern and laboratory parameters sensu left ventricular global systolic function. A total of 109 STEMI patients were examined. The patients underwent contrast-enhanced cardiac MRI with a 1.5 Tesla GE SIGNA Voyager (GE HealthCare, Chicago, IL, USA) on the 7th-10th days from the onset of the disease...
March 11, 2024: Diagnostics
https://read.qxmd.com/read/38533295/hemodynamic-determinants-of-cardiac-surgery-associated-acute-kidney-injury
#6
JOURNAL ARTICLE
Sevag Demirjian, Faisal Bakaeen, W H Wilson Tang, Chase Donaldson, Jon Taliercio, Anne Huml, Crystal A Gadegbeku, A Marc Gillinov, Steven Insler
OBJECTIVES: Examine the: 1) relative role of hemodynamic determinants of acute kidney injury (AKI) obtained in the immediate postcardiac surgery setting compared with established risk factors, 2) their predictive value, and 3) extent mediation via central venous pressure (CVP) and mean arterial pressure (MAP). DESIGN: Retrospective observational study. The main outcome of the study was moderate to severe AKI, per kidney disease: improving global outcomes, within 14 days of surgery...
April 2024: Critical care explorations
https://read.qxmd.com/read/38532301/safety-of-lung-resection-surgery-after-severe-acute-respiratory-syndrome-coronavirus-2-infection-in-the-post-vaccination-era
#7
JOURNAL ARTICLE
Somin Im, Kwon Joong Na, Ji Hyeon Park, Bubse Na, Samina Park, In Kyu Park, Chang Hyun Kang, Young Tae Kim
OBJECTIVES: To investigate the post-operative outcomes of lung resection in patients with SARS-CoV-2 infection and determine the optimal timing of surgery. METHODS: This retrospective, single-center cohort study included patients who underwent lung resection between June 2021 and June 2022. Patients were divided into the COVID-19 and non-COVID-19 groups based on their pre-operative SARS-CoV-2 infection history, and post-operative outcomes were compared. Logistic regression analysis was conducted to identify the risk factors of complications after lung resection surgery...
March 26, 2024: European Journal of Cardio-thoracic Surgery
https://read.qxmd.com/read/38531926/cardiac-troponin-i-as-predictor-for-cardiac-and-other-mortality-in-the-german-randomized-lung-cancer-screening-trial-lusi
#8
JOURNAL ARTICLE
Francisco O Cortés-Ibáñez, Theron Johnson, Mario Mascalchi, Verena Katzke, Stefan Delorme, Rudolf Kaaks
Cardiac Troponin I (cTnI) could be used to identify individuals at elevated risk of cardiac death in lung cancer (LC) screening settings. In a population-based, randomized LC screening trial in Germany ("LUSI" study) serum cTnI was measured by high-sensitivity assay in blood samples collected at baseline, and categorized into unquantifiable/low (< 6 ng/L), intermediate (≥ 6-15 ng/L), and elevated (≥ 16 ng/L). Cox proportional-hazard models were used to estimate risk of all-cause and cardiac mortality with cTnI levels...
March 26, 2024: Scientific Reports
https://read.qxmd.com/read/38531890/highlighting-the-effects-of-high-intensity-interval-training-on-the-changes-associated-with-hypertrophy-apoptosis-and-histological-proteins-of-the-heart-of-old-rats-with-type-2-diabetes
#9
JOURNAL ARTICLE
Mohammad Rami, Amirhossein Ahmadi Hekmatikar, Samaneh Rahdar, Sayed Shafa Marashi, D Maryama Awang Daud
T2DM is known to cause disturbances in glucose homeostasis and negative changes in the heart muscle, while aging and diabetes are recognized risk factors for CVD. Given this, our study aims to investigate a method for controlling and managing CVDs induced by T2DM in elderly populations. To achieve this, we categorized 40 rats into 5 groups, including HAD (n = 8), HA (n = 8), AD (n = 8), AHT (n = 8), and ADT (n = 8). The exercise protocol consisted of eight weeks of HIIT (three sessions per week) performed at 90-95% of maximal speed...
March 26, 2024: Scientific Reports
https://read.qxmd.com/read/38531574/association-between-osteoarthritis-and-cardiovascular-disease-in-elderly-in-japan-an-administrative-claims-database-analysis
#10
JOURNAL ARTICLE
Takuya Uematsu, Shuko Nojiri, Muneaki Ishijima, Yuji Nishizaki
OBJECTIVE: To investigate whether osteoarthritis (OA) is a risk factor for cardiovascular disease (CVD); whether there are differences concerning ischaemic heart disease (IHD), congestive heart failure (CHF) and stroke; and whether there are differences between OA sites (hips, knees and hand) in predicting CVD onset. DESIGN: Population-based matched case-control study. SETTING: Health insurance claims data among Japanese patients. PARTICIPANTS: Japanese patients aged ≥65 years with newly diagnosed CVD and hospitalised between January 2015 and December 2020 (cases) and age-matched and sex-matched 1:1 individuals (controls)...
March 25, 2024: BMJ Open
https://read.qxmd.com/read/38531031/heart-failure-related-to-contemporary-breast-cancer-treatment
#11
JOURNAL ARTICLE
Megan Durkin, Neisha DeJesus
This article addresses cardiotoxicity in patients with breast cancer who are treated with anthracyclines and/or anti-human epidermal growth factor 2 (HER2) therapy, namely doxorubicin and trastuzumab. Development of concise clinical guidelines for chemotherapy-induced heart failure is ongoing. Through identification of specific risk factors and clinical predictors of cardiotoxicity, clinicians are able to better understand and define effective monitoring strategies and optimize patient care. Close cardiac monitoring is recommended for patients throughout treatment with anthracyclines and anti-HER2 therapy...
April 1, 2024: JAAPA: Official Journal of the American Academy of Physician Assistants
https://read.qxmd.com/read/38530978/perioperative-immune-checkpoint-blockades-improve-prognosis-of-resectable-non-small-cell-lung-cancer
#12
JOURNAL ARTICLE
Yu Tian, Zhichao Liu, Hanbo Pan, Hongda Zhu, Ningyuan Zou, Long Jiang, Ziming Li, Jia Huang, Yingjie Hu, Qingquan Luo
OBJECTIVES: Immune checkpoint blockades (ICB) have been proven to improve prognosis of non-small cell lung (NSCLC) in the neoadjuvant setting, while whether its perioperative use could bring extra benefit remained unidentified. We aimed to demonstrate the prognostic benefit of perioperative ICB over preoperative-only use and investigate who could benefit from this "sandwich ICB therapy". METHODS: Patients undergoing neoadjuvant therapy followed by surgery from 2018 to 2022 was retrospectively reviewed, and were divided into four groups based on the perioperative regimens: pre-ICB + post-CT, pre-ICB-only, pre-CT + post-ICB, and pre-CT-only...
March 26, 2024: European Journal of Cardio-thoracic Surgery
https://read.qxmd.com/read/38530802/risk-factors-for-long-term-mortality-after-acute-aortic-dissection-results-of-the-german-registry-for-acute-aortic-dissection-type-a-long-term-follow-up
#13
JOURNAL ARTICLE
Andreas Böning, John-Arved Kretzer, Rawa Arif, Christian D Etz, Jochen Pöling, Bartosz Rylski, Martin Czerny, Jens Brickwedel, Sven Peterss, Tomas Holubec, Philipp Jawny, Manuel Feißt
OBJECTIVES: Several short-term analyses from German registry for acute aortic dissection type A (GERAADA) have been published. This study investigated whether short-term risk factors are transferable to the long-term prognosis of patients. METHODS: 33 centers with 2686 patients participated in the long-term follow-up. 1164 patients died, 1063 survived and 459 were lost to follow-up during the follow-up timeframe (mean duration: 10.2 years). Long-term mortality of the cohort was compared with an age-stratified, German population...
March 26, 2024: European Journal of Cardio-thoracic Surgery
https://read.qxmd.com/read/38530573/association-between-elevated-body-mass-index-and-cardiac-organ-damage-in-children-and-adolescents-evidence-and-mechanisms
#14
JOURNAL ARTICLE
Alessandra Annaloro, Chiara Invernizzi, Francisco Aguilar, Julio Alvarez, Cesare Cuspidi, Guido Grassi, Empar Lurbe
INTRODUCTION: Although a number of pathophysiological aspects of childhood obesity have been reported, few information are available on obesity-related cardiac organ damage. AIM: The present study was aimed at assessing the impact of anthropometric, blood pressure (BP) and metabolic variable on cardiac structure and function in youth. METHODS: In 78 subjects aged 5-16 years attending the outpatient clinic of cardiovascular risk (Valencia, Spain) anthropometric and metabolic variables, clinic and ambulatory BP and echocardiographic parameters were assessed...
March 26, 2024: High Blood Pressure & Cardiovascular Prevention: the Official Journal of the Italian Society of Hypertension
https://read.qxmd.com/read/38529922/-staphylococcus-aureus-bacteraemia-cardiac-implantable-electronic-device-extraction-and-the-risk-of-recurrent-infection-a-retrospective-population-based-cohort-study
#15
JOURNAL ARTICLE
Andreas Berge, Casper Carlsén, Alexandros Petropoulos, Fredrik Gadler, Magnus Rasmussen
BACKGROUND: Patients with cardiac implantable electronic device (CIED) and Staphylococcus aureus bacteraemia (SAB) are at risk of having CIED infection, pocket infection or endocarditis. To avoid treatment failures, guidelines recommend that the CIED should be extracted in all cases of SAB butrecent studies indicate low extraction rates and low risk of relapse. The aim of the study was to describe a Swedish population-based cohort of patients with CIED and SAB, the rate of extraction, and treatment failure measured as recurrent SAB...
March 26, 2024: Infectious Diseases
https://read.qxmd.com/read/38529434/recovery-and-survival-of-patients-after-out-of-hospital-cardiac-arrest-a-literature-review-showcasing-the-big-picture-of-intensive-care-unit-related-factors
#16
REVIEW
Srdjan S Nikolovski, Aleksandra D Lazic, Zoran Z Fiser, Ivana A Obradovic, Jelena Z Tijanic, Violetta Raffay
As an important public health issue, out-of-hospital cardiac arrest (OHCA) requires several stages of high quality medical care, both on-field and after hospital admission. Post-cardiac arrest shock can lead to severe neurological injury, resulting in poor recovery outcome and increased risk of death. These characteristics make this condition one of the most important issues to deal with in post-OHCA patients hospitalized in intensive care units (ICUs). Also, the majority of initial post-resuscitation survivors have underlying coronary diseases making revascularization procedure another crucial step in early management of these patients...
February 2024: Curēus
https://read.qxmd.com/read/38528580/fibrinogen-to-hdl-cholesterol-ratio-as-a-predictor-of-mortality-risk-in-patients-with-acute-myocardial-infarction
#17
JOURNAL ARTICLE
Congzhuo Jia, Wanying Wu, Huan Lu, Jin Liu, Shiqun Chen, Guoxiao Liang, Yang Zhou, Sijia Yu, Linfang Qiao, Jinming Chen, Ning Tan, Yong Liu, Jiyan Chen
BACKGROUND: Acute myocardial infarction (AMI) is characterized by inflammation, oxidative stress, and atherosclerosis, contributing to increased mortality risk. High-density lipoprotein (HDL) takes a crucial part in mitigating atherosclerosis and inflammation through its diverse functionalities. Conversely, fibrinogen is implicated in the development of atherosclerotic plaques. However, the mortality risk predictive capacity of fibrinogen to HDL-cholesterol ratio (FHR) in AMI patients remains unexplored...
March 25, 2024: Lipids in Health and Disease
https://read.qxmd.com/read/38528572/characteristics-of-traumatic-major-haemorrhage-in-a-tertiary-trauma-center
#18
JOURNAL ARTICLE
Pieter van Wyk, Marcus Wannberg, Anna Gustafsson, Jane Yan, Agneta Wikman, Louis Riddez, Carl-Magnus Wahlgren
BACKGROUND: Major traumatic haemorrhage is potentially preventable with rapid haemorrhage control and improved resuscitation techniques. Although advances in prehospital trauma management, haemorrhage is still associated with high mortality. The aim of this study was to use a recent pragmatic transfusion-based definition of major bleeding to characterize patients at risk of major bleeding and associated outcomes in this cohort after trauma. METHODS: This was a retrospective cohort study including all trauma patients (n = 7020) admitted to a tertiary trauma center from January 2015 to June 2020...
March 25, 2024: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://read.qxmd.com/read/38528469/a-nomogram-model-for-predicting-intramyocardial-hemorrhage-post-pci-based-on-syntax-score-and-clinical-features
#19
JOURNAL ARTICLE
Yin-Shuang Yang, De-Yang Xi, Yang Duan, Miao Yu, Kai Liu, Yan-Kai Meng, Chun-Feng Hu, Shu-Guang Han, Kai Xu
OBJECTIVE: The aim of this study is to develop a nomogram model for predicting the occurrence of intramyocardial hemorrhage (IMH) in patients with Acute Myocardial Infarction (AMI) following Percutaneous Coronary Intervention (PCI). The model is constructed utilizing clinical data and the SYNTAX Score (SS), and its predictive value is thoroughly evaluated. METHODS: A retrospective study was conducted, including 216 patients with AMI who underwent Cardiac Magnetic Resonance (CMR) within a week post-PCI...
March 25, 2024: BMC Cardiovascular Disorders
https://read.qxmd.com/read/38526935/association-of-left-ventricular-diastolic-dysfunction-with-inflammatory-activity-renal-dysfunction-and-liver-related-mortality-in-patients-with-cirrhosis-and-ascites
#20
JOURNAL ARTICLE
Georgios Kalambokis, Maria Christaki, Ilias Tsiakas, Grigorios Despotis, Lampros Lakkas, Spiridon Tsiouris, Xanthi Xourgia, Georgios S Markopoulos, Lefkothea Dova, Haralampos Milionis
Left ventricular diastolic dysfunction (LVDD) is the predominant cardiac abnormality in cirrhosis. We investigated the association of LVDD with systemic inflammation and its impact on renal function, occurrence of hepatorenal syndrome (HRS) and survival in patients with cirrhosis and ascites. We prospectively enrolled 215 patients with cirrhosis and ascites. We evaluated the diagnosis and grading of LVDD by Doppler echocardiography, inflammatory markers, systemic hemodynamics, vasoactive factors, radioisotope-assessed renal function and blood flow, HRS development and liver-related mortality...
March 19, 2024: European Journal of Gastroenterology & Hepatology
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