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patient safty

Luchuan Chen, Shenghong Wei, Zaisheng Ye, Jun Xiao, Yi Zeng, Yi Wang, Zhenmeng Lin, Zhitao Lin, Xiaoling Chen
OBJECTIVE: To evaluate the safty and feasibility of the D2 radical resection of omental bursa and No.12p and No.8p for gastric carcinoma (GC). METHODS: Clinical data of 1801 GC patients undergoing D2 radical resection of omental bursa and No.12p and No.8p at Fujian Medical University Cancer Hospital from January 2000 to January 2010 were analyzed retrospectively. Inclusion case criteria: (1)age of 18 to 90 years;(2)pathologically diagnosed as GC and receiving D2 radical resection of omental bursa and No...
February 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
Qi-Fei Xu, Kui-Ran Lin, Dai-Jie Zhao, Song-Qin Zhang, Sheng-Kai Feng, Chen Li
OBJECTIVE: To investigate the application and effect of minimally invasive percutaneous anterior pelvic pubic ramus screw fixation in Tile B fractures. METHODS: A retrospective review was conducted on 56 patients with posterior pelvic ring injury combined with fractures of anterior pubic and ischiadic ramus treated between May 2010 and August 2015, including 31 males and 25 females with an average age of 36.8 years old ranging from 35 to 65 years old. Based on the Tile classification, there were 13 cases of Tile B1 type, 28 cases of Tile B2 type and 15 cases of Tile B3 type...
March 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
D Bazyka
After the creation of the Academy of Medical Sciences of Ukraine in 1993 the Research Center for Radiation Medicine was among the first institutions to join the Academy (fig. 1). Estab lishing the Academy was among the first steps of the independent Ukrainian government and aimed to provide a high level health care for population. It was extremely needed for the minimization of Chornobyl medical consequences. This choice was related to a growing recognition of the scientific research in fulfilling the Сenter's mission - study of the effects of low dose radiation on human body and radiation protection of the exposed population...
December 2017: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
M S Zaki, M Y Issa, H M Elbendary, H El-Karaksy, H Hosny, C Ghobrial, A El Safty, A El-Hennawy, A Oraby, L Selim, M S Abdel-Hamid
Biallelic mutations in the SLC30A10 gene cause an inborn error of Mn metabolism characterized by hypermanganesemia, polycythemia, early-onset dystonia, and liver cirrhosis (HMDPC). To date, only 14 families from various ethnic groups have been reported. Here, we describe 10 patients from 7 unrelated Egyptian families with HMDPC. Markedly elevated blood Mn levels, the characteristic basal ganglia hyperintensity on T1-weighted images, and variable degrees of extrapyramidal manifestations with or without liver disease were cardinal features in all patients...
November 28, 2017: Clinical Genetics
Haiting Chen, Guangzeng Niu, Yuxiang Fan, Jingxue Ma
BACKGROUD: The Implantable Collamer Lens (ICL) has been used widely for refractive errors, We performed this prospective randomized comparative study to compare postoperative intraocular pressure (IOP) and vaults of the eyes implanted with conventional ICL and central hole ICL. METHODS: This study evaluated 44 eyes of 22 patients who underwent central hole ICL implantation in one eye and conventional ICL implantation in the other eye by randomization assignment...
November 16, 2016: BMC Ophthalmology
Sandra Mühlstädt, Alexander Friedl, Nasreldin Mohammed, André Schumann, Karl Weigand, Felix Kawan, Christian Göllert, Christin Kahlert, Gerit Theil, Kersten Fischer, Paolo Fornara
BACKGROUND: We report on our 5-year experience with the adjustable transobturator male system (ATOMS(®,) A.M.I., Feldkirch, Austria). METHODS: Between 10-2009 and 10-2014, 54 patients received an ATOMS. The mean follow-up of this retrospective observational trial was 27.5 ± 18.4 (2.3-59) months. Within each follow-up, the following were evaluated: micturition protocol, 24-h pad count, uroflowmetry and residual volume. Statistical analysis was performed with SigmaPlot(®) 11...
January 2017: World Journal of Urology
Xiao-Shu Liu, Hui Long, Yu-Xian Huang, Jian-Hui Xu, Jun-Yu Zhu, Qing-Feng DU, Bing-Yi Wu
OBJECTIVE: To study the efficacy and safety of sorafenib combined with low dose cytarabine for treating patients with FLT3(+) relapsed and refractory acute myeloid leukemia (FLT3(+) RR-AML). METHODS: Seven patients with FLT3(+) RR-AML were treated with sorafenib and low dose cytarabine. The curative rate and adverse effects were observed in these patients. RESULTS: Out of 7 RR-AML patients after treatment, 5 patients achieved complete remission (CR), 2 patients achieved partial remission (PR), and the overall response rate (ORR) after one course of therapy was 100%...
April 2016: Zhongguo Shi Yan Xue Ye Xue za Zhi
Jiang Wang, Qing-Bo Li, Yuan-Yuan Wu, Bao-Ning Wang, Jin-Long Kang, Xue-Wu Xu
Etomidate is a widely used hypnotic drug for induction of general anesthesia and sedation, especially in elderly patients and hemodynamically unstable patients. Myoclonus, however, is the most prominent problem during induction of anesthesia with etomidate. Many agents have been used to prevent it and opioid is one of them. This meta-analysis was to evaluate effects of opioids pretreatment for preventing etomidate-induced myoclonus. We searched the PubMed, EMBASE, and the Cochrane Library databases and published studies in English updated to September 2015...
February 2, 2016: American Journal of Therapeutics
Naeem Akhtar, Sherif A El-Safty, Mamdouh E Abdelsalam, Hiroshi Kawarada
Selective and sensitive glucose sensors with fast response for screening diabetic blood level are demanded. In this paper, the one-pot nanoarchitecture of dendritic NiO@carbon-nitrogen (C-N) dots (designated as NCD) sphere-wrapping Ni foam electrodes are reported as an effective and sensitive glucose sensor in blood samples. In this construction design, the NCD sphere electrode with excessive surface defects, large fractions of catalytic active sites, high surface area, and mobility of electron transfer through the actively surface NCD sphere can massively enhance the electrocatalytic activity for nonenzymatic glucose detection in diabetic blood...
August 21, 2015: Advanced Healthcare Materials
Mohamed S El-Shimi, Rania A El-Farrash, Eman A Ismail, Ibrahim A El-Safty, A El-Safty, Ahmed S Nada, Omayma A El-Gamel, Yomna M Salem, Sara M Shoukry
BACKGROUND: Iron deficiency anemia (IDA) is the most common nutritional deficiency in the world. The aim of our study was to evaluate and compare renal functional and structural integrity in 50 infants with IDA and 50 healthy controls and to assess the relation between IDA and oxidative stress and response to iron therapy. METHODS: This was a prospective study in which peripheral blood samples were collected from all study subjects and the following laboratory investigations performed: serum iron profile, urinary microalbumin, urinary leucine aminopeptidase (LAP), fractional excretion of sodium (FeNa), serum total antioxidant capacity (TAC), serum malondialdehyde (MDA), serum and urinary trace elements (iron, copper, zinc, calcium and magnesium)...
October 2015: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
You-xin Ji, Zhong-fa Zhang, Ke-tao Lan, Ke-ke Nie, Chuan-xin Geng, Shi-chao Liu, Ling Zhang, Xing-jun Zhuang, Xiao Zou, Lei Sun, Zong-chun Zhang
OBJECTIVE: To explore the efficacy and safty of sorafenib in Child-Pugh class B to class C hepatocellular carcinoma (HCC). METHODS: In this three-center open-label study from November 2011 to May 2013, we randomly assigned 189 patients with advanced Child-Pugh class B or C HCC patients into two groups, one group with 95 patient to receive sorafenib (400 mg a time, twice a day) and the other group with 94 patients to receive best supportive care. The primary end points were progression-free survival and overall survival...
March 2014: Chinese Medical Sciences Journal, Chung-kuo i Hsüeh K'o Hsüeh Tsa Chih
B Paudel, B K Shrestha, A K Banskota
Objectives: To review the indications for major lower limb amputations in adults and children in our patient population and to compare our experience in prosthetic rehabilitation with that of other published information. Material and Methods: We retropectively reviewed charts of patients who underwent amputation between 1997 to 2004 at the Orthopaedic Department of B& B Hospital (BBH ) , Gwarko and Hospital and Rehabilitation center for Disabled Children ( HRDC), Banepa. There were 113 patients at BBH & 89 patients at HRDC ...
2005: Kathmandu University Medical Journal (KUMJ)
Jia Shi, Yue-Fu Wang, Qing-Hua Xue, Su Yuan, Gu-Yan Wang, Li-Huan Li
OBJECTIVE: To evaluate the effectiveness and safty of tranexamic acid in patients receiving on-pump coronary artery bypass grafting (CABG) without clopidogrel and aspirin cessation. METHODS: The current study is a prospective, randomized and placebo-control trial. A total of 116 patients receiving selective on-pump CABG with their last ingestion of clopidogrle and aspirin within 7 days preoperatively were recruited. Despite 6 patients withdrawal their consent, the rest 110 were randomized to receive tranexamic acid or placebo...
June 1, 2013: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
Cui-long Liu, Yun Ouyang, Jian-jun Guo, Mao-jun Zhou, Er-xun Lu, Wei-min Guan
OBJECTIVE: To evaluate the efficacy and safty of photoselective vaporization of prostate (PVP) in the treatment of benign prostatic hyperplasia with obstruction within 5 years. METHODS: From December 2004 to December 2009, there were 782 cases have been except for neurogenic bladder dysfunction and prostate cancer, who received PVP surgical treatment of BPH. The surgical conditions and postoperative follow-up data were recorded and the follow-up cut-off time for surgery after 5 years...
February 1, 2013: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
Wanxu Gao, Shijun Mi, Jingchun Gao
OBJECTIVE: To evaluate the effectiveness of percutaneous vertebroplasty (PVP) in the treatment of osteoporotic vertebral compression fractures with or without intravertebral clefts by unilateral approach and the impact of intravertebral clefts on the effectiveness. METHODS: The clinical data of 65 patients who met the inclusion criteria of osteoporotic vertebral compression fracture were retrospectively analyzed. According to having intravertebral clefts or not, the patients were divided into 2 groups: cleft group (group A, n=25) and non-cleft group (group B, n=40)...
November 2012: Chinese Journal of Reparative and Reconstructive Surgery
Eun Ju Lee, Hee Kyeong Lim, Min Kyung Shin, Dong-Hye Suh, Sang-Jun Lee, Nack In Kim
BACKGROUND: Acne vulgaris is the most common skin disease worldwide, with many available treatment modalities, including oral and topical medications and laser therapy. Recently, a novel device (Isolaz, Pleasanton, CA, USA) that combines vacuum pressure and a broadband light source (400 nm to 1,200 nm) was developed for the treatment of acne. OBJECTIVE: To determine the clinical efficacy and safety of photopneumatic therapy for the treatment of acne vulgaris of the face...
August 2012: Annals of Dermatology
Feng-wei Li, Guan-chao Jiang, Yun Li, Liang Bu, Fan Yang, Jian-feng Li, Hui Zhao, Yan-guo Liu, Zu-li Zhou, Jun Liu, Jun Wang
OBJECTIVE: To evaluate the safty, thoroughness and efficacy of the video-assisted thoracoscopic surgery compared with open thoracotomy, in treatment of patients with the preoperative staging of lymph node negative and postoperative pathological mediastinal lymph node positive (cN0-pN2) locally advanced non-small cell lung cancer(NSCLC). METHODS: We performed a retrospective review of 616 patients who underwent either VATS lobectomy or open thoracotomy from July 2000 to December 2009...
December 18, 2011: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
Yabin Wu, Zhen Long, Yang Huang, Xuanzhao Huang
OBJECTIVE: To evaluate the adverse reaction of standardized specific mite-allergen immunotherapy. METHOD: One hundred and fifty-two patients diagnosed by the pediatric immunotherapy center of our hospital were treated with increasing doses of standardized specific mite-allergen injection. Before and 30 minutes after treatment, the peak expiratory flow (PEF) and pulmonary function for the maximum lung ventilation function were checked, and the adverse reactions were recorded...
July 2011: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Kaihua Lu, Yan Han, Shuzhong Guo
OBJECTIVE: To summarize and review the development and experience of anastomosis vascular pedicle free composite tissue flap. METHODS: From July 1987 to March 2007, 321 patients with complete records were treated. Fourteen tissue flaps were applied for the repair of trauma or tumor excision defects of the body, and for organ reconstruction. RESULTS: Vascular crisis occurred in 20 patients within 48 hours postoperatively. Necrosis occurred at flap end in 6 patients...
September 2007: Chinese Journal of Reparative and Reconstructive Surgery
Xiao-dong Huang, Jun-lin Yi, Li Gao, Guo-zhen Xu, Jing Jin, Wei-zhi Yang, Tai-xiang Lu, Shao-xiong Wu, Ren-rui Wu, Wei-han Hu, Wei-chang Xie, Fei Han, Yuan-hong Gao, Jian-ming Gao, Jian-ji Pan, Chuan-ben Chen, Jin-yi Lang, Tao Li, Yu Dong, Yu-bing Fu, Lin Fan, Bo-sen Li, Jing Li, Xiao-huai Wang, Bing-xu Chen, Xian-shu Gao, Ping Zhang, Xiang-wei Wu, Bing-qiang Hu
OBJECTIVE: To evaluate the efficacy and safty of the humanized anti-epidermal factor receptor monoclonal antibody h-R3 in combination with radiotherapy for locoregionally advanced nasopharyngeal carcinoma. METHODS: Totally, 137 patients from 7 medical center around China were randomly divided into combined therapy group or control group. There was no difference in Karnofsky performance score between two groups. All patients in both groups received radical conventionally fractionated radiotherapy to the total dose of D(T) 70-76 Gy...
March 2007: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
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