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https://www.readbyqxmd.com/read/27852246/comparison-of-intraocular-pressure-andvault-after-implantation-of-implantable-collamer-lens-with-and-without-a-central-hole
#1
Haiting Chen, Guangzeng Niu, Yuxiang Fan, Jingxue Ma
BACKGROUD: The Implantable Collamer Lens (ICL) has been used widely for refractive errors, We performed this prospective randomized comparative study to compare postoperative intraocular pressure (IOP) and vaults of the eyes implanted with conventional ICL and central hole ICL. METHODS: This study evaluated 44 eyes of 22 patients who underwent central hole ICL implantation in one eye and conventional ICL implantation in the other eye by randomization assignment...
November 16, 2016: BMC Ophthalmology
https://www.readbyqxmd.com/read/27156092/five-year-experience-with-the-adjustable-transobturator-male-system-for-the-treatment-of-male-stress-urinary-incontinence-a-single-center-evaluation
#2
Sandra Mühlstädt, Alexander Friedl, Nasreldin Mohammed, André Schumann, Karl Weigand, Felix Kawan, Christian Göllert, Christin Kahlert, Gerit Theil, Kersten Fischer, Paolo Fornara
BACKGROUND: We report on our 5-year experience with the adjustable transobturator male system (ATOMS(®,) A.M.I., Feldkirch, Austria). METHODS: Between 10-2009 and 10-2014, 54 patients received an ATOMS. The mean follow-up of this retrospective observational trial was 27.5 ± 18.4 (2.3-59) months. Within each follow-up, the following were evaluated: micturition protocol, 24-h pad count, uroflowmetry and residual volume. Statistical analysis was performed with SigmaPlot(®) 11...
May 7, 2016: World Journal of Urology
https://www.readbyqxmd.com/read/27150998/-clinical-efficacy-of-sorafenib-combined-with-low-dose-cytarabine-for-treating-patients-with-flt3-relapsed-and-refractory-acute-myeloid-leukemia
#3
Xiao-Shu Liu, Hui Long, Yu-Xian Huang, Jian-Hui Xu, Jun-Yu Zhu, Qing-Feng DU, Bing-Yi Wu
OBJECTIVE: To study the efficacy and safety of sorafenib combined with low dose cytarabine for treating patients with FLT3(+) relapsed and refractory acute myeloid leukemia (FLT3(+) RR-AML). METHODS: Seven patients with FLT3(+) RR-AML were treated with sorafenib and low dose cytarabine. The curative rate and adverse effects were observed in these patients. RESULTS: Out of 7 RR-AML patients after treatment, 5 patients achieved complete remission (CR), 2 patients achieved partial remission (PR), and the overall response rate (ORR) after one course of therapy was 100%...
April 2016: Zhongguo Shi Yan Xue Ye Xue za Zhi
https://www.readbyqxmd.com/read/26840341/efficacy-and-safty-of-opioids-for-the-prevention-of-etomidate-induced-myoclonus-a-meta-analysis
#4
Jiang Wang, Qing-Bo Li, Yuan-Yuan Wu, Bao-Ning Wang, Jin-Long Kang, Xue-Wu Xu
Etomidate is a widely used hypnotic drug for induction of general anesthesia and sedation, especially in elderly patients and hemodynamically unstable patients. Myoclonus, however, is the most prominent problem during induction of anesthesia with etomidate. Many agents have been used to prevent it and opioid is one of them. This meta-analysis was to evaluate effects of opioids pretreatment for preventing etomidate-induced myoclonus. We searched the PubMed, EMBASE, and the Cochrane Library databases and published studies in English updated to September 2015...
February 2, 2016: American Journal of Therapeutics
https://www.readbyqxmd.com/read/26293491/one-pot-fabrication-of-dendritic-nio-carbon-nitrogen-dot-electrodes-for-screening-blood-glucose-level-in-diabetes
#5
Naeem Akhtar, Sherif A El-Safty, Mamdouh E Abdelsalam, Hiroshi Kawarada
Selective and sensitive glucose sensors with fast response for screening diabetic blood level are demanded. In this paper, the one-pot nanoarchitecture of dendritic NiO@carbon-nitrogen (C-N) dots (designated as NCD) sphere-wrapping Ni foam electrodes are reported as an effective and sensitive glucose sensor in blood samples. In this construction design, the NCD sphere electrode with excessive surface defects, large fractions of catalytic active sites, high surface area, and mobility of electron transfer through the actively surface NCD sphere can massively enhance the electrocatalytic activity for nonenzymatic glucose detection in diabetic blood...
August 21, 2015: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/25980471/renal-functional-and-structural-integrity-in-infants-with-iron-deficiency-anemia-relation-to-oxidative-stress-and-response-to-iron-therapy
#6
Mohamed S El-Shimi, Rania A El-Farrash, Eman A Ismail, Ibrahim A El-Safty, A El-Safty, Ahmed S Nada, Omayma A El-Gamel, Yomna M Salem, Sara M Shoukry
BACKGROUND: Iron deficiency anemia (IDA) is the most common nutritional deficiency in the world. The aim of our study was to evaluate and compare renal functional and structural integrity in 50 infants with IDA and 50 healthy controls and to assess the relation between IDA and oxidative stress and response to iron therapy. METHODS: This was a prospective study in which peripheral blood samples were collected from all study subjects and the following laboratory investigations performed: serum iron profile, urinary microalbumin, urinary leucine aminopeptidase (LAP), fractional excretion of sodium (FeNa), serum total antioxidant capacity (TAC), serum malondialdehyde (MDA), serum and urinary trace elements (iron, copper, zinc, calcium and magnesium)...
October 2015: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/24698672/sorafenib-in-liver-function-impaired-advanced-hepatocellular-carcinoma
#7
RANDOMIZED CONTROLLED TRIAL
You-xin Ji, Zhong-fa Zhang, Ke-tao Lan, Ke-ke Nie, Chuan-xin Geng, Shi-chao Liu, Ling Zhang, Xing-jun Zhuang, Xiao Zou, Lei Sun, Zong-chun Zhang
OBJECTIVE: To explore the efficacy and safty of sorafenib in Child-Pugh class B to class C hepatocellular carcinoma (HCC). METHODS: In this three-center open-label study from November 2011 to May 2013, we randomly assigned 189 patients with advanced Child-Pugh class B or C HCC patients into two groups, one group with 95 patient to receive sorafenib (400 mg a time, twice a day) and the other group with 94 patients to receive best supportive care. The primary end points were progression-free survival and overall survival...
March 2014: Chinese Medical Sciences Journal, Chung-kuo i Hsüeh K'o Hsüeh Tsa Chih
https://www.readbyqxmd.com/read/24097448/two-faces-of-major-lower-limb-amputations
#8
B Paudel, B K Shrestha, A K Banskota
Objectives: To review the indications for major lower limb amputations in adults and children in our patient population and to compare our experience in prosthetic rehabilitation with that of other published information. Material and Methods: We retropectively reviewed charts of patients who underwent amputation between 1997 to 2004 at the Orthopaedic Department of B& B Hospital (BBH ) , Gwarko and Hospital and Rehabilitation center for Disabled Children ( HRDC), Banepa. There were 113 patients at BBH & 89 patients at HRDC ...
2005: Kathmandu University Medical Journal (KUMJ)
https://www.readbyqxmd.com/read/24091268/-effectiveness-and-safety-of-tranexamic-acid-in-patients-receiving-on-pump-coronary-artery-bypass-grafting-without-clopidogrel-and-aspirin-cessation
#9
RANDOMIZED CONTROLLED TRIAL
Jia Shi, Yue-Fu Wang, Qing-Hua Xue, Su Yuan, Gu-Yan Wang, Li-Huan Li
OBJECTIVE: To evaluate the effectiveness and safty of tranexamic acid in patients receiving on-pump coronary artery bypass grafting (CABG) without clopidogrel and aspirin cessation. METHODS: The current study is a prospective, randomized and placebo-control trial. A total of 116 patients receiving selective on-pump CABG with their last ingestion of clopidogrle and aspirin within 7 days preoperatively were recruited. Despite 6 patients withdrawal their consent, the rest 110 were randomized to receive tranexamic acid or placebo...
June 1, 2013: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/23711002/-follow-up-observation-of-photoselective-vaporization-of-prostate-for-treatment-of-benign-prostatic-hyperplasia-within-five-years
#10
Cui-long Liu, Yun Ouyang, Jian-jun Guo, Mao-jun Zhou, Er-xun Lu, Wei-min Guan
OBJECTIVE: To evaluate the efficacy and safty of photoselective vaporization of prostate (PVP) in the treatment of benign prostatic hyperplasia with obstruction within 5 years. METHODS: From December 2004 to December 2009, there were 782 cases have been except for neurogenic bladder dysfunction and prostate cancer, who received PVP surgical treatment of BPH. The surgical conditions and postoperative follow-up data were recorded and the follow-up cut-off time for surgery after 5 years...
February 1, 2013: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/23230667/-percutaneous-vertebroplasty-to-treat-osteoporotic-vertebral-compression-fractures-combined-with-intravertebral-clefts-by-unilateral-approach
#11
Wanxu Gao, Shijun Mi, Jingchun Gao
OBJECTIVE: To evaluate the effectiveness of percutaneous vertebroplasty (PVP) in the treatment of osteoporotic vertebral compression fractures with or without intravertebral clefts by unilateral approach and the impact of intravertebral clefts on the effectiveness. METHODS: The clinical data of 65 patients who met the inclusion criteria of osteoporotic vertebral compression fracture were retrospectively analyzed. According to having intravertebral clefts or not, the patients were divided into 2 groups: cleft group (group A, n=25) and non-cleft group (group B, n=40)...
November 2012: Chinese Journal of Reparative and Reconstructive Surgery
https://www.readbyqxmd.com/read/22879711/an-open-label-split-face-trial-evaluating-efficacy-and-safty-of-photopneumatic-therapy-for-the-treatment-of-acne
#12
Eun Ju Lee, Hee Kyeong Lim, Min Kyung Shin, Dong-Hye Suh, Sang-Jun Lee, Nack In Kim
BACKGROUND: Acne vulgaris is the most common skin disease worldwide, with many available treatment modalities, including oral and topical medications and laser therapy. Recently, a novel device (Isolaz, Pleasanton, CA, USA) that combines vacuum pressure and a broadband light source (400 nm to 1,200 nm) was developed for the treatment of acne. OBJECTIVE: To determine the clinical efficacy and safety of photopneumatic therapy for the treatment of acne vulgaris of the face...
August 2012: Annals of Dermatology
https://www.readbyqxmd.com/read/22178835/-preliminary-comparison-research-of-thoracoscopy-and-thoracotomy-lobectomy-for-clinical-n0-and-post-operatively-pathological-n2-non-small-cell-lung-cancer
#13
COMPARATIVE STUDY
Feng-wei Li, Guan-chao Jiang, Yun Li, Liang Bu, Fan Yang, Jian-feng Li, Hui Zhao, Yan-guo Liu, Zu-li Zhou, Jun Liu, Jun Wang
OBJECTIVE: To evaluate the safty, thoroughness and efficacy of the video-assisted thoracoscopic surgery compared with open thoracotomy, in treatment of patients with the preoperative staging of lymph node negative and postoperative pathological mediastinal lymph node positive (cN0-pN2) locally advanced non-small cell lung cancer(NSCLC). METHODS: We performed a retrospective review of 616 patients who underwent either VATS lobectomy or open thoracotomy from July 2000 to December 2009...
December 18, 2011: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/22032122/-study-on-safty-of-standardized-specific-mite-allergen-immunotherapy-to-children-with-allergic-rhinitis-and-or-asthma
#14
Yabin Wu, Zhen Long, Yang Huang, Xuanzhao Huang
OBJECTIVE: To evaluate the adverse reaction of standardized specific mite-allergen immunotherapy. METHOD: One hundred and fifty-two patients diagnosed by the pediatric immunotherapy center of our hospital were treated with increasing doses of standardized specific mite-allergen injection. Before and 30 minutes after treatment, the peak expiratory flow (PEF) and pulmonary function for the maximum lung ventilation function were checked, and the adverse reactions were recorded...
July 2011: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/17933227/-application-and-development-of-free-composite-tissue-flap-in-plastic-surgery
#15
Kaihua Lu, Yan Han, Shuzhong Guo
OBJECTIVE: To summarize and review the development and experience of anastomosis vascular pedicle free composite tissue flap. METHODS: From July 1987 to March 2007, 321 patients with complete records were treated. Fourteen tissue flaps were applied for the repair of trauma or tumor excision defects of the body, and for organ reconstruction. RESULTS: Vascular crisis occurred in 20 patients within 48 hours postoperatively. Necrosis occurred at flap end in 6 patients...
September 2007: Chinese Journal of Reparative and Reconstructive Surgery
https://www.readbyqxmd.com/read/17649636/-multi-center-phase-ii-clinical-trial-of-humanized-anti-epidermal-factor-receptor-monoclonal-antibody-h-r3-combined-with-radiotherapy-for-locoregionally-advanced-nasopharyngeal-carcinoma
#16
RANDOMIZED CONTROLLED TRIAL
Xiao-dong Huang, Jun-lin Yi, Li Gao, Guo-zhen Xu, Jing Jin, Wei-zhi Yang, Tai-xiang Lu, Shao-xiong Wu, Ren-rui Wu, Wei-han Hu, Wei-chang Xie, Fei Han, Yuan-hong Gao, Jian-ming Gao, Jian-ji Pan, Chuan-ben Chen, Jin-yi Lang, Tao Li, Yu Dong, Yu-bing Fu, Lin Fan, Bo-sen Li, Jing Li, Xiao-huai Wang, Bing-xu Chen, Xian-shu Gao, Ping Zhang, Xiang-wei Wu, Bing-qiang Hu
OBJECTIVE: To evaluate the efficacy and safty of the humanized anti-epidermal factor receptor monoclonal antibody h-R3 in combination with radiotherapy for locoregionally advanced nasopharyngeal carcinoma. METHODS: Totally, 137 patients from 7 medical center around China were randomly divided into combined therapy group or control group. There was no difference in Karnofsky performance score between two groups. All patients in both groups received radical conventionally fractionated radiotherapy to the total dose of D(T) 70-76 Gy...
March 2007: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/16467873/targeting-gene-virotherapy-of-cancer
#17
REVIEW
Xin Yuan Liu, Jin Fa Gu
Our purpose is to completely elimination of xenograft tumor in animal tumor model in order to work out a protocal for the cure of patient. Gene therapy and viral therapy for cancer have got some therapeutic effects, but both have no great breakthrough. Therefore, we worked out a new strategy called Targeting Gene-Virotherapy of Cancer which is a combination of the advantage of gene therapy and virotherapy. This new strategy has stronger antitumor effect than either of them alone. A tumor specific replicative adenovirus vector ZD55 (E1B 55KD deleted Adv...
January 2006: Cell Research
https://www.readbyqxmd.com/read/15828262/-safety-and-efficacy-of-a-new-vessel-sealing-device-for-laparoscopic-varicocelectomy
#18
Hiroshi Kiuchi, Minoru Koga, Toshiaki Hirai, Yukiomi Namba, Masami Takeyama
PURPOSE: To evaluate the safety and efficacy of a new vessel-sealing device (LigaSure) for laparoscopic varicocelectomy. MATERIALS AND METHODS: To evaluate the safty, after elective varicocelectomy, the internal spermatic veins (n = 8) were sealed ex vivo with a 5-mm laparoscopic Maryland-style LigaSure (LigaSure Lap), and bursting pressures were measured. To evaluate the efficacy, a retrospective review of our clinical experience with LigaSure (n = 13) and clip (n = 13) in laparoscopic bilatelal varicocelectomy from June 2000 to October 2002 was performed and certain parameters were abstracted, including operative time, estimated blood loss and perioperative complications...
March 2005: Nihon Hinyōkika Gakkai Zasshi. the Japanese Journal of Urology
https://www.readbyqxmd.com/read/12905678/-an-appraisal-of-immunonutrition-for-clinical-nutritional-support-with-a-systematic-review-of-english-and-chinese-documents
#19
Hua Jiang, Zhu-ming Jiang, Bin Luo, Xiao Shuai, You-ping Li
OBJECTIVE: To evaluate the efficacy, safty and economical values of immunonutrition for clinical nutritional support. METHODS: The following electronic databases were searched: Chinese Biomedicine database (CBM), MEDLINE, EMBASE, Cochrane Library and SCI. Data were extracted by two reviewers. RevMan 4.1 was applied for statistical analysis. RESULTS: Seventeen randomised trials comparing the use of immunonutrition which comprises nucleotides, omega-3 fatty acids and arginine with standard enteral nutrition in surgical, trauma/burn and critical illness patients...
December 2002: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/12640285/glomerular-and-tubular-dysfunction-in-children-with-congenital-cyanotic-heart-disease-effect-of-palliative-surgery
#20
Hesham Awad, Ibrahim el-Safty, Moustafa Abdel-Gawad, Salwa el-Said
BACKGROUND: Nephropathy has long been recognized as a potential complication of congenital cyanotic heart disease (CCHD). The present study was undertaken to investigate some aspects of glomerular function by measuring urinary total protein, microalbumin, and tubular function by assessing urinary alpha-1-microglobulin. The structural integrity of the renal proximal tubules was also studied by measuring urinary activities of the brush-border enzyme leucine-aminopeptidase and the lysosomal enzyme -acetyl-beta-d-glucosaminidase...
March 2003: American Journal of the Medical Sciences
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