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Synchronous colon and advanced gastric cancer

Byung Wook Choi, Hae Won Kim, Kyoung Sook Won, Bong-Il Song, Kwang Bum Cho, Sung Uk Bae
Preoperative screening for synchronous colorectal neoplasia (CRN) has been recommended in patients with gastric cancer because patients with gastric cancer are at increased risk for synchronous CRN. The aim of this study was to investigate the diagnostic accuracy of F-fluorodeoxyglucose (F-FDG) positron emission tomography/computed tomography (PET/CT) for detecting synchronous advanced CRN in patients with gastric cancer.A total of 256 patients who underwent colonoscopy and F-FDG PET/CT for preoperative staging were enrolled in this study...
September 2016: Medicine (Baltimore)
Xiao Tian Zhang, Wei Wang, Qiang Zhu, Ming Cao, Zhong Min Jiang, Q I Zang
With the continuous advancement of clinical diagnostic techniques, including imaging technology, the incidence of confirmed multiple primary cancers or double primary carcinoma increases yearly. However, studies reporting synchronization surgery performed for primary dual esophageal gastric cancer are rare. The present study reports the case of a patient with double primary esophageal-gastric cancer, located in the thoracic cavity segment of the esophagus and gastric antrum of the stomach, respectively. The gastric cancer was diagnosed by endoscopy biopsy with concomitant esophageal cancer...
August 2015: Oncology Letters
Kazuhito Yajima, Shin-Ichi Kosugi, Yosuke Kano, Takaaki Hanyu, Hiroshi Ichikawa, Takashi Ishikawa, Hitoshi Nogami, Toshifumi Wakai
Laparoscopic treatment strategies for synchronous intra-abdominal malignancies have not yet been standardized. We report a successful case of two-step laparoscopic surgery for synchronous double cancer of the colon and stomach accompanied by severe chronic obstructive pulmonary disease (COPD). A 66-year-old man with COPD was diagnosed as having advanced colon cancer and early gastric cancer. On admission, he could not go upstairs (Grade III according to the Hugh-Jones classification) and his forced expiratory volume in 1 second was 600 mL (35...
2013: Case Reports in Surgery
Makoto Takeda, Toshiyuki Ori, Kimio Ohishi, Kenichi Sunayama
A 71-year-old man was diagnosed with gastric cancer[cT4, cN0, cH1(S6), cP0, cM0, cStage IV]and underwent distal gastrectomy with cholecystectomy, partial colectomy for the invasion to the mesentery of transverse colon, and partial hepatectomy for metastatic liver tumor(segment 6). Although chemotherapy with S-1+CDDP was administered after the operation, a recurrent lesion appeared in the remnant of liver(segment 6). The chemotherapy regimen was changed to S-1+CPT-11. Since the only recurrent tumor was found in the remnant liver, it was resected...
May 2013: Gan to Kagaku Ryoho. Cancer & Chemotherapy
I Huţanu, D Timofte, V Scripcariu, C Diaconu
UNLABELLED: Peritoneal carcinomatosis of gastrointestinal origin (PC-GI) is an advanced digestive tumor and is found in 10-30% of patients (P) with primary surgery for cancer (C) and up to 50% of C recurrences. AIM: To evaluate the main characteristics, ethio-pathogenesis, prognosis and imaging to track of P with PC-GI admitted to the Third Surgical Clinic, "St. Spiridon" Hospital, Iaşi. MATERIAL AND METHODS: A retrospective study was carried out on series of 203 patients admitted in the period June 2006 - March 2011...
January 2012: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
Junhyun Lee, Yuhee Nam, Wook Kim
PURPOSE: Concurrent laparoscopic surgery for the synchronous gastric and colon cancer in one patient is not only a rare procedure, but also has some demerits such as longer operation time, more blood loss, and the use of additional laparoscopic ports. Moreover, laparoscopy-assisted distal gastrectomy with extraperigastric lymph node dissection is still controversial in the case of advanced gastric cancer. METHODS: We report the successful laparoscopic surgery of a 78-year-old patient with synchronous advanced gastric and right colon cancers...
August 2010: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
Sang Nam Yoon, Sung Tae Oh, Seok-Byung Lim, Tae Won Kim, Jong Hoon Kim, Chang Sik Yu, Jin Cheon Kim
BACKGROUND: We investigated the characteristics of synchronous and metachronous gastric cancer in patients with colorectal cancer. METHODS: We reviewed 8,680 patients who underwent operations for primary sporadic colorectal cancer from 1989 to 2008. Synchronous gastric cancer was defined as gastric cancer diagnosed within 6 months of a colorectal cancer diagnosis. Gastric cancer diagnosed more than 6 months before or after colorectal cancer was defined as metachronous...
September 2010: World Journal of Surgery
Hideaki Uchiyama, Masaru Morita, Yasushi Toh, Hiroshi Saeki, Yoshihiro Kakeji, Hiroshi Matsuura, Yoshihiko Maehara
The fear of serious complications, such as a necrotic conduit caused by an impaired blood circulation can arise when replacing the esophagus with an intestinal conduit. The aim of this paper is to present effective superdrainage of an intestinal conduit using an inferior mesenteric vein (IMV) interposition graft. In 2008, we performed superdrainage of the ileocolic vein to the internal jugular vein interposed by an IMV graft in replacing the esophagus with the right hemicolon for advanced thoracic esophageal cancer in three patients with a synchronous gastric cancer or a previous gastrectomy...
June 2010: Surgery Today
Milind Javle, Chung-Tsen Hsueh
We have reviewed the pivotal presentations related to gastrointestinal malignancies from 2009 annual meeting of the American Society of Clinical Oncology with the theme of "personalizing cancer care". We have discussed the scientific findings and the impact on practice guidelines and ongoing clinical trials. Adding trastuzumab to chemotherapy improved the survival of patients with advanced gastric cancer overexpressing human epidermal growth factor receptor 2. Gemcitabine plus cisplatin has become a new standard for first-line treatment of advanced biliary cancer...
2010: Journal of Hematology & Oncology
Mariateresa Mirarchi, Emilio De Raffele, Stefania Lega, Lucia Calculli, Samuele Vaccari, Bruno Cola
Intraductal papillary mucinous neoplasms are a well-recognized pathologic entity of the pancreas that is being reported with increasing frequency. These tumours carry a relatively favourable prognosis and are frequently associated with extrapancreatic malignancies. The combination of advanced age and co-existence of two neoplasms challenges the planning of the best treatment option. A 78-year-old man presented with rectal bleeding which led to the diagnosis of a stenosing adenocarcinoma of the sigmoid colon...
May 2009: Chirurgia Italiana
Takashi Akiyoshi, Hiroya Kuroyanagi, Masatoshi Oya, Akio Saiura, Shigekazu Ohyama, Yoshiya Fujimoto, Masashi Ueno, Rintaro Koga, Makoto Seki, Naoki Hiki, Tetsu Fukunaga, Tsuyoshi Konishi, Meiki Fukuda, Toshiharu Yamaguchi
BACKGROUND/AIMS: Although laparoscopy is accepted for treatment of colon cancer, its use for rectal cancer still has technical limitations. Whether a laparoscopic approach for rectal cancer is safe and beneficial remains unknown when simultaneous open upper major abdominal surgery is planned. METHODOLOGY: Eight patients underwent laparoscopic rectal resection for primary rectal cancer combined with open upper major abdominal surgery. RESULTS: All laparoscopic rectal resections were successful, with no conversion to open surgery...
May 2009: Hepato-gastroenterology
Hideo Matsui, Yuichi Okamoto, Akiko Ishii, Kazuhiro Ishizu, Yasumasa Kondoh, Naoki Igarashi, Kyoji Ogoshi, Hiroyasu Makuuchi
In gastric cancer patients, the most common form of synchronous cancer is colorectal cancer. To reduce the invasiveness of the resection, a laparoscopy-assisted combined resection was performed in three patients with synchronous gastric and colorectal cancer. Although all gastric lesions were in the early stages, two colorectal lesions were advanced cases. In all cases, the laparoscopic gastric resection and reconstruction was performed first, followed by the colorectal resection. In the case of right-side colon cancer in addition to gastric cancer, it was relatively easy to perform the combined resection with lymph node dissection sharing the same ports used for the gastrectomy, although we needed an additional port...
2009: Surgery Today
Panagiotis Yannopoulos, Panagiotis Theodoridis, Konstantinos Manes
OBJECTIVE: This study aimed to review and evaluate our experience in 750 patients, who underwent transhiatal esophagectomy (THE) and analyze our data. Special attention was paid to some strategies, which we developed in the course of time, regarding the postoperative management of these patients and formulation of improved guidelines. PATIENTS AND METHODS: This is a retrospective analysis of all THE operations performed between January 1981 until May 2007 in 750 patients: 60 patients (8%) had benign lesions, while 690 (92%) had malignant ones (5...
July 2009: Langenbeck's Archives of Surgery
Dae Won Jun, Oh Young Lee, Hyun Chul Lim, Sung Joon Kwon, Hang Lak Lee, Byung Chul Yoon, Ho Soon Choi, Joon Soo Hahm, Min Ho Lee, Dong Hoo Lee
AIM: To examine the diagnostic yield of colorectal neoplasia at computed tomographic colonoscopy (CTC) as well as the feasibility of contrast enhanced CTC in patients with gastric cancer. METHODS: To examine the incidence of colon polyp we selected postoperative 188 gastric cancer patients, which we refer to as the 'colon polyp survey group'. To examine the feasibility of CTC for early detection of colon cancer or advanced colon adenoma, we selected 47 gastric cancer patients (M:F 29:18, mean age 53...
March 21, 2007: World Journal of Gastroenterology: WJG
A Giuliani, M Demoro, M Corona, M Di Bari, T Ricciardulli, G Galati, A Ciardi
An unusual case of advanced synchronous colon and gastric carcinoma is described. A 36 year old female was admitted to our Department with a stenosing right colon cancer diagnosed at endoscopy which was performed for lower crampy abdominal pain and gross blood in the stool. Multiple colon polyps, distal to the tumor, were also detected. On preoperative abdominal computed tomography, a stenosing right colon cancer, without evidence of abdominal diffusion, was confirmed. At laparotomy, in addition to colon cancer, an antral gastric cancer was incidentally found...
March 2005: Journal of Experimental & Clinical Cancer Research: CR
Masashi Ueno, Tetsuichiro Muto, Masatoshi Oya, Hirotoshi Ota, Kaoru Azekura, Toshiharu Yamaguchi
BACKGROUND: Cancer patients are at high risk of developing a second cancer after the treatment of initial cancers. Understanding the characteristics of multiple primary cancer is important to establish an effective surveillance program for the early detection of second cancers. METHODS: We analyzed the cancer registry records from 1986 to 1995 at the Cancer Institute Hospital. The combination of the sites of the index and second cancers and the time intervals between the two cancers were examined...
June 2003: International Journal of Clinical Oncology
S Onoue, T Katoh, H Chigira, K Matsuo, M Suzuki, Y Shibata, M Maeda
We describe herein the cases of two aged patients found to have synchronous multiple primary cancers of the stomach and duodenum. The first patient was an 82-year-old man who was preoperatively diagnosed as having gastric cancer after presenting with signs of pyloric stenosis. At laparotomy, duodenal cancer was incidentally found to have infiltrated the transverse colon. A pancreatoduodenectomy and right hemicolectomy with radical lymph node dissection was performed. Two early well-differentiated adenocarcinomas of the stomach and an advanced poorly differentiated adenocarcinoma of the duodenum were confirmed...
2000: Surgery Today
K Yoshino, S Nara, M Endo
This paper describes-the indications for, the main points of the surgical technique, and the results of composite reconstruction using a combination of pediculated and free tissue units, which has allowed extensive and complex reconstruction following resection of malignant tumors in the head and neck region or in the esophagus. Composite reconstruction was indicated for synchronous or metachronous carcinomas in the head and neck region and the esophagus (Groups 1 and 2) or for secondary reconstruction of the esophagus (Group 3)...
1996: Microsurgery
O Yasuna, Y Hatayama, T Karibe, M Ookura, Y Munakata, K Nishimaki, H Koike, Y Yamaura, M Ogiwara
The incidence of associated synchronous or heterochronous malignant tumors in this series was 3.3% (21/633). These patients were found more in multiple cancer than single cancer of the stomach. A relatively high incidence of associated cancer of other organs was found with cancer of the large bowel and of the cervix in heterochronous cancer and cancer of the esophagus in synchronous tumors. The cumulative corrected 10-year survival rate of 15 cases of heterochronous tumors was 85.7%. On the other hand, six patients with synchronous tumor had more advanced cancer of other organs than gastric cancer, and four of them died due to cancer of other organs within two years...
December 1984: Gan No Rinsho. Japan Journal of Cancer Clinics
J A Sparano, E L Schwartz, K M Salva, M F Pizzillo, S Wadler, P H Wiernik
Ten previously untreated patients with gastric cancer were treated with etoposide, 120 mg/m2 intravenously (i.v.) on days 4, 5, and 6, Adriamycin, 20 mg/m2 i.v. on days 1 and 7, and cisplatin, 40 mg/m2 i.v. on days 2 and 8 (EAP). Etoposide, 240 mg/m2 on days 4, 5, and 6, was administered orally instead of intravenously in alternating cycles, and pharmacokinetic studies were performed in those who had previously undergone gastrectomy or who had tumor infiltrating the stomach to determine oral bioavailability...
October 1990: American Journal of Clinical Oncology
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