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tb and paraplegia

Eva M N Wouda, Ymkje Stienstra, Tjip S van der Werf, Huib Kerstjens, Wiel C M de Lange, Maarten Coppes, Jos Kuijlen, Marga Tepper, Onno W Akkerman
BACKGROUND: Spinal tuberculosis (TB) accounts for approximately 1% to 3% of all TB cases and it can cause a wide range of neurological symptoms, from none to a complete spinal cord injury (SCI), resulting in complete paraplegia or tetraplegia. OBJECTIVES: To describe the functional and neurological outcome of SCI caused by TB. METHODS: Retrospective data on the admission period was combined with prospectively collected data on long-term follow-up...
February 10, 2017: NeuroRehabilitation
J Tayierjiang, N Waresijiang, H Wang
Objective: To evaluate the clinical results of the patients with severe kyphosis and paraplegia in different spine segment due to tuberculosis of thoracic and lumbar had been treated by one stage posterior surgical procedure to debriment of lesion and titian mesh bone fusion with internal fixation by pedicle screw system. Method: From May 2008 to March 2014, there were total 30 patients with severe kyphosis and paraplegia in different spine segment due to tuberculosis of thoracic and lumbar in Department of Orthopaedics, the People's Hospital of Xinjiang Uygur Autonoumy Region...
October 11, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Emna Toulgui, Sonia Jemni, Samia Frioui, Nadia Lazreg, Sahbi Mtaouaa, Fayçal Khachnaoui
OBJECTIVE: Tuberculous spondylitis, or Pott's disease, is a public health problem in Tunisia, where it occurs as an endemic disease. It is the most common and most severe articular bone tuberculosis. It is responsible for a major handicap because of its location and its destructive nature. This work aims to assess the contribution of rehabilitation for patients with Pott's disease. MATERIAL/PATIENTS AND METHODS: A retrospective study that included 29 patients with Pott's disease and hospitalized in PMR Service...
September 2016: Annals of Physical and Rehabilitation Medicine
Laila Mahir, Soumia Meftah, Siham Zahi, Herman Azanmasso, Fatima Lmidmani, Abdellatif El Fatimi
OBJECTIVE: Tuberculosis of the central nervous system is a major cause of morbidity and mortality in developing countries. Myelitis is the most common manifestation of spinal tuberculosis. OBJECTIVE: we report the epidemiological characteristics, clinical and functional aspects in a group of 14 patients with tuberculous myelitis after functional rehabilitation. MATERIALS/PATIENTS AND METHODS: Over a period of 4 years, 14 cases of tuberculous myelitis were admitted for functional rehabilitation...
September 2016: Annals of Physical and Rehabilitation Medicine
George Sikalengo, Adria Ramirez, Diana Faini, Kim Mwamelo, Manuel Battegay, Levan Jugheli, Christoph Hatz, Klaus Reither, Emilio Letang
BACKGROUND: Extrapulmonary tuberculosis (EPTB) is associated with high rates of morbidity and mortality. Diagnosis of EPTB is challenging in resource-limited settings due to difficulties in obtaining samples, as well as the paucibacillarity of the specimens. Skeletal tuberculosis accounts for 10-35 % of EPTB cases, with vertebral osteomyelitis (Pott's disease) representing 50 % of the cases. We present two cases of suspected Pott's disease, diagnosed through GeneXpert MTB/RIF assay in urine at a rural Tanzanian hospital...
September 26, 2016: BMC Infectious Diseases
Teoman Aydın, Özgür Taşpınar, Yasar Keskin, Müge Kepekçi, Meryem Güneşer, Adil Çamlı, Hakan Seyithanoğlu, Huriye Kızıltan, Ali Hikmet Eriş
BACKGROUND: Tuberculous radiculomyelitis(TBRM) is one of the complications of neurological tuberculosis and includes cases of arachnoiditis, intradural spinal tuberculoma or granuloma, and spinal cord complications of tuberculous meningitis (TBM). Here, we report a case of TBRM which presented with acute paraplegia. CASE DETAILS: Neurological examination on admission revealed flaccid paralysis, bilateral extensor plantar responses, and exaggerated deep tendon reflexes...
July 2016: Ethiopian Journal of Health Sciences
Kush Kumar
PURPOSE: To describe the natural history spinal tuberculosis, classifications and principles of management based upon the grading of the neurological deficit. METHODS: Review of literature was conducted with the aim to provide the clinico-radiological correlation of the natural history of spinal tuberculosis in different stages. Management strategy is developed based upon the severity of the neurological deficit. RESULTS: A five stage natural history of spinal tuberculosis is described...
August 2016: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
Z Guo, M Yao, J Wang, K Sun, Z Ji
Objective: This work aims to investigate the efficacy of debridement for paediatric thoracolumbar spinal tuberculosis (TB) by using the anterior approach and the allogeneic bone graft. Methods: The lesions of 16 children diagnosed with thoracolumbar spinal TB were exposed via the anterior approach. The pleura and peritoneum, granulation tissue, pus and dead bones of the TB, and the intervertebral disc with pathological changes and necrosis were completely eliminated...
December 10, 2015: West Indian Medical Journal
Dhanesheshwar N Lanjewar, Varsha Omprakash Bhatia, Sonali Dhaneshwar Lanjewar
BACKGROUND: Human immunodeficiency virus (HIV) infection in India has now been prevalent over three decades, and an increasing number of children are being affected with HIV. The spectrum of pathologic lesions in children with acquired immunodeficiency syndrome (AIDS) in India has not been well described. MATERIALS AND METHODS: A review of systematically conducted autopsies of 11 (10 boys and 1 girl) children with AIDS is presented. RESULTS: The mode of HIV transmission in 6 children was vertical; in one it was blood transfusion and in 4 children route was presumably vertical as these were children of orphanage...
April 2016: Indian Journal of Pathology & Microbiology
Nikhil Jain, Namita Singh Saini, Sudhir Kumar, Mukunth Rajagopalan, Kanti Lal Chakraborti, Anil Kumar Jain
INTRODUCTION: Diffusion tensor imaging (DTI) has been used in cervical trauma and spondylotic myelopathy, and it has been found to correlate with neural deficit and prognosticate neural recovery. Such a correlation has not been studied in Pott's spine with paraplegia. Hence, this prospective study has been used to find correlation of DTI parameters with neural deficit in these patients. METHODS: Thirty-four patients of spinal TB were enrolled and DTI was performed before the start of treatment and after six months...
2016: SICOT-J
S Kaushal, S K Dora, S Thakur
Spinal tuberculosis leading to paraplegia is uncommon in pregnancy and is a diagnostic and therapeutic challenge. We report a case of tubercular paraplegia presenting at 35 weeks of gestation. She was managed with Anti-tubercular drugs and did not require surgical intervention. Her neurological status improved and she was allowed to go in labour. She delivered a healthy term infant by cesarean. At three months follow-up, both mother and child are doing well.
April 2015: JNMA; Journal of the Nepal Medical Association
Yu-Xiang Wang, Hong-Qi Zhang, Weiwei Liao, Ming-Xing Tang, Chao-Feng Guo, Ang Deng, Jian-Huang Wu, Jin-Yang Liu
PURPOSE: Aged patients represent a high risk group for acquiring spinal tuberculosis, and it still remains a leading cause of kyphosis and paraplegia in developing nations. Aged patients often combined with cardiovascular and respiratory disease and single lung ventilation via anterior approach surgery could result in more post-operative complications. We aimed to analyze the efficacy and feasibility of surgical management of aged patients with lumbo-sacral spine tuberculosis using one-stage posterior focus debridement, interbody graft using titanium mesh cages, posterior instrumentation, and fusion...
June 2016: International Orthopaedics
S N Singh, Trilok C Bhatt, Savit Kumar, Vikas Chauhan, Anjali Pandey
Tuberculosis of cervical spine is an extremely rare entity in infants with only few case reports available in the literature. The diagnosis is often delayed due to less dramatic effects of paraplegia or quadriplegia in an infant as compared to older paediatric population. Along with clinical and laboratory investigations, imaging plays a crucial role in defining the extent of involvement, evaluation of complications, providing suitable differential diagnosis and monitoring response to treatment. Tuberculosis typically involves the discovertebral complex while involvement of isolated vertebral body or multiple vertebrae without involving the intervertebral discs is much less common...
January 2016: Journal of Clinical and Diagnostic Research: JCDR
Bin Yu, Ke Zhu, Deng Zhao, Fei Wang, Yijian Liang
STUDY DESIGN: A case report of treatment of extreme tuberculous kyphosis using spinal osteotomy and halopelvic traction. OBJECTIVE: The aim of this study was to describe the process and outcome of treatment of a case with extreme tuberculous kyphosis using spine osteotomy and halo-pelvic traction. SUMMARY OF BACKGROUND DATA: Spinal tuberculosis causes destruction, deformity, and paraplegia. Long-standing kyphosis may progress with growth in children, and produces respiratory insufficiency, and neurologic deficit...
February 2016: Spine
Shaheen A Bhatty, Hari Lal, Abu Talib, Khalid Mahmood, Iftekhar Naqvi, Syeda Shaheera Zaidi
Neuromyelitis Optica (NMO), previously regarded as a form of multiple sclerosis, is defined by Gault and Devic, as a retrobulbar neuritis or papillitis accompanied by acute myelitis and occasionally other neurological symptom or signs not restricted to the spinal cord or optic nerves. With the diagnosis of specific antibodies, probable role of humoral immunity supports its pathogenesis. Only a few cases of NMO have been reported in association with pulmonary tuberculosis (TB). Here we report a case of young girl with acute onset paraplegia diagnosed to have NMO, who later on during hospital stay developed ascites which cultured positive for Mycobacterium tuberculosis...
October 2015: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
Ijaz Hussain Wadd, Ainullah Khan, Abdullah Haroon, Anjum Habib Vohra
OBJECTIVE: To evaluate the surgical outcome of anterior decompression, grafting and fixation in tuberculosis of the dorsal and lumbar spine with compression over the neural tissue and neural deficit. STUDY DESIGN: A case series. PLACE AND DURATION OF STUDY: Department of Neurosurgery Unit-I, Lahore General Hospital, Lahore, from January 2008 to March 2012. METHODOLOGY: Patients with caries spine having compression over the thecal sac with neurological deficit and kyphosis were included in the study...
October 2015: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
Mrcs T Zin-Naing
The aims of spinal tuberculosis treatment are to eradicate the disease, to prevent the development of paraplegia and kyphotic deformity, to manage the existing deformity and neurological deficit, to allow early ambulation and to return the patient back to daily life. Methods for the treatment of tuberculosis of vertebra are still controversial. Conservative treatment includes medical therapy as well as external supports and surgery is indicated for deformity of spine, severe pain, or neurological compromise conditions...
November 2014: Malaysian Orthopaedic Journal
A Batirel, H Erdem, G Sengoz, F Pehlivanoglu, E Ramosaco, S Gülsün, R Tekin, B Mete, I I Balkan, D Y Sevgi, E Giannitsioti, A Fragou, S Kaya, B Cetin, T Oktenoglu, A D Celik, B Karaca, E S Horasan, M Ulug, S Senbayrak, S Kaya, E Arslanalp, R Hasbun, S Ates-Guler, A Willke, S Senol, D Inan, E Güclü, G T Ertem, M M Koc, M Tasbakan, G Ocal, S Kocagoz, H Kusoglu, T Güven, A I Baran, B Dede, F Y Karadag, H Yilmaz, G Aslan, D A Al-Gallad, S Cesur, R El-Sokkary, F Sirmatel, U Savasci, G Karaahmetoglu, H Vahaboglu
We aimed to describe clinical, laboratory, diagnostic and therapeutic features of spinal tuberculosis (ST), also known as Pott disease. A total of 314 patients with ST from 35 centres in Turkey, Egypt, Albania and Greece were included. Median duration from initial symptoms to the time of diagnosis was 78 days. The most common complications presented before diagnosis were abscesses (69%), neurologic deficits (40%), spinal instability (21%) and spinal deformity (16%). Lumbar (56%), thoracic (49%) and thoracolumbar (13%) vertebrae were the most commonly involved sites of infection...
November 2015: Clinical Microbiology and Infection
Jean-Luc Baudel, Vincent Dubée, Juliette Palle, Hafid Ait-Oufella
No abstract text is available yet for this article.
January 2016: American Journal of Medicine
Dong-Yoon Lee, Sang-Pyo Kim, In-Soo Kim
Spinal intramedullary tuberculoma remains a very rare entity of central nervous system tuberculosis. This is the same with the coexistence of spinal intramedullary and intracranial tuberculomas that remains extremely rare with less than 20 cases reported at present. Authors describe this uncommon case by analyzing a 65-year-old female patient who had past history of kidney transplantation due to stage 5 chronic kidney disease and pulmonary tuberculosis on medication. The patient experiences progressive paraplegia and numbness on both lower extremities...
June 2015: Korean Journal of Spine
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