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https://www.readbyqxmd.com/read/28963161/tuberculosis-of-the-spine-with-severe-angular-kyphosis-mean-34-year-post-operative-follow-up-shows-that-prevention-is-better-than-salvage
#1
Y W Wong, D Samartzis, K M C Cheung, K Luk
AIMS: To address the natural history of severe post-tuberculous (TB) kyphosis, with focus upon the long-term neurological outcome, occurrence of restrictive lung disease, and the effect on life expectancy. PATIENTS AND METHODS: This is a retrospective clinical review of prospectively collected imaging data based at a single institute. A total of 24 patients of Southern Chinese origin who presented with spinal TB with a mean of 113° of kyphosis (65° to 159°) who fulfilled inclusion criteria were reviewed...
October 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28796043/smith-petersen-osteotomy-combined-with-anterior-debridement-and-allografting-for-active-thoracic-and-lumbar-spinal-tuberculosis-with-kyphotic-deformity-in-young-children-a-prospective-study-and-literature-review
#2
Yakefu Abulizi, Wei-Dong Liang, Maierdan Maimaiti, Wei-Bin Sheng
The purpose of this study is to determine the efficacy and safety of Smith-Petersen osteotomy combined with anterior debridement and allogenic strut bone grafting for the treatment of active thoracic and lumbar spinal tuberculosis with kyphotic deformity in young children.Spinal tuberculosis is more destructive in young children and often causes severe kyphosis and paraplegia. Despite much progress has been made, surgical treatment is still controversial and technically challenging.From October 2010 to August 2014, 25 children (11 males, 14 females; aged under 6 years) with active thoracic and lumbar spinal tuberculosis treated by Smith-Petersen osteotomy combined with anterior debridement and allogenic strut bone grafting were enrolled in this study...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28720997/ossified-ligamentum-flavum-causing-neurological-deficit-above-the-level-of-post-tuberculous-kyphotic-deformity
#3
Suresh Subramani, Ajoy Prasad Shetty, Rishi Mugesh Kanna, Rajasekaran Shanmuganathan
Late onset paraplegia is a rare complication of spinal tuberculosis. Disease reactivation and cord compression by internal gibbus are the common causes for neurological deficit. We report a patient with post-tubercular kyphotic deformity in whom the late onset paraplegia is caused by ossified ligamentum flavum above the level of kyphotic deformity. The deficit was attributable to the ossified ligamentum flavum and she recovered completely following posterior decompression and instrumented posterolateral fusion...
April 2017: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28558705/disseminated-cryptococcosis-with-recurrent-multiple-abscesses-in-an-immunocompetent-patient-a-case-report-and-literature-review
#4
REVIEW
Qiaoling Ruan, Yimin Zhu, Shu Chen, Liping Zhu, Shu Zhang, Wenhong Zhang
BACKGROUND: Cryptococcus neoformans is frequently present as an opportunistic pathogen mainly affecting immunocompromised populations. Disseminated C. neoformans infection in immunocompetent population is rare and usually involves lung and central nerve system. Cryptococcus from biologic samples can easily grow on routine fungal and bacterial culture media. Besides, cryptococcal latex agglutination test has been established as a reliable diagnostic tool with overall sensitivities of 93-100%...
May 30, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28532916/spinal-intramedullary-tuberculosis-with-concurrent-supra-and-infratentorial-intracranial-disease-in-a-9-month-old-boy-case-report-and-comprehensive-review-of-the-literature
#5
REVIEW
Michael George Zaki Ghali, Visish M Srinivasan, Marc J Kim, Archana Malik
BACKGROUND: Tuberculous involvement of the spinal cord parenchyma is an exceedingly rare clinical entity; even more so is concurrent intracranial tuberculosis (TB). Spinal intramedullary TB presents with a characteristic subacute myelopathy, with slowly progressive paraplegia, sensory deficits, and/or bowel and bladder dysfunction. Diagnosis is strongly suspected with a clinical history of known TB in conjunction with characteristic findings on magnetic resonance imaging. Management involves multiagent antitubercular chemotherapy without or with operative intervention...
October 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28526568/analysis-of-complications-following-posterior-vertebral-column-resection-for-the-treatment-of-severe-angular-kyphosis-greater-than-100%C3%A2
#6
Yunus Atici, Mehmet Bulent Balioglu, Deniz Kargin, Muhammed Mert, Akif Albayrak, Mehmet Akif Kaygusuz
OBJECTIVE: The aim of this study was to evaluate the complications, efficacy and safety of posterior vertebral column resection (PVCR) in severe angular kyphosis (SAK) greater than 100°. METHODS: The medical records of 17 patients (mean age 17.9 (range, 9-27) years) with SAK who underwent PVCR, were reviewed. Mean follow-up period was 32.2 (range, 24-64) months. Diagnosis of the patients included congenital kyphosis in 11 patients, post-tuberculosis kyphosis in 3 patients and neurofibromatosis in 3 patients...
May 16, 2017: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/28435564/acute-paraplegia-in-a-toddler-a-diagnostic-journey-compounding-the-challenge-in-management-a-case-report
#7
J H Goh, M Fazir, N A Zainal-Abidin, D Amir, M Singh
Spinal tuberculosis is not common in the paediatric age group. Initial clinical features are often vague and non specific until the disease progresses to later stages. We highlight the diagnostic difficulties and management challenges of a complicated extradural tuberculoma with neurological deficits in a very young girl.
July 2016: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/28222564/neurological-and-functional-recovery-in%C3%A2-tuberculosis-patients-with-spinal-cord%C3%A2-injury-in-the-netherlands
#8
Eva M N Wouda, Ymkje Stienstra, Tjip S van der Werf, Huib Kerstjens, Wiel C M de Lange, Maarten Coppes, Jos Kuijlen, Marga Tepper, Onno W Akkerman
BACKGROUND: Spinal tuberculosis (TB) accounts for approximately 1% to 3% of all TB cases and it can cause a wide range of neurological symptoms, from none to a complete spinal cord injury (SCI), resulting in complete paraplegia or tetraplegia. OBJECTIVES: To describe the functional and neurological outcome of SCI caused by TB. METHODS: Retrospective data on the admission period was combined with prospectively collected data on long-term follow-up...
2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/27760661/-clinical-results-of-the-patients-with-severe-kyphosis-and-paraplegia-in-different-spine-segment-due-to-tuberculosis-of-thoracic-and-lumbar-treated-by-one-stage-posterior-surgical-procedure-to-debriment-of-lesion-bone-fusion-with-internal-fixation-by-pedicle
#9
J Tayierjiang, N Waresijiang, H Wang
Objective: To evaluate the clinical results of the patients with severe kyphosis and paraplegia in different spine segment due to tuberculosis of thoracic and lumbar had been treated by one stage posterior surgical procedure to debriment of lesion and titian mesh bone fusion with internal fixation by pedicle screw system. Method: From May 2008 to March 2014, there were total 30 patients with severe kyphosis and paraplegia in different spine segment due to tuberculosis of thoracic and lumbar in Department of Orthopaedics, the People's Hospital of Xinjiang Uygur Autonoumy Region...
October 11, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27677045/management-in-a-rehabilitation-department-in-pott-s-disease
#10
Emna Toulgui, Sonia Jemni, Samia Frioui, Nadia Lazreg, Sahbi Mtaouaa, Fayçal Khachnaoui
OBJECTIVE: Tuberculous spondylitis, or Pott's disease, is a public health problem in Tunisia, where it occurs as an endemic disease. It is the most common and most severe articular bone tuberculosis. It is responsible for a major handicap because of its location and its destructive nature. This work aims to assess the contribution of rehabilitation for patients with Pott's disease. MATERIAL/PATIENTS AND METHODS: A retrospective study that included 29 patients with Pott's disease and hospitalized in PMR Service...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27676773/functional-results-after-rehabilitation-of-tuberculosis-myositis-experience-of-pmr-unit-of-chu-ibn-rochd-casablanca
#11
Laila Mahir, Soumia Meftah, Siham Zahi, Herman Azanmasso, Fatima Lmidmani, Abdellatif El Fatimi
OBJECTIVE: Tuberculosis of the central nervous system is a major cause of morbidity and mortality in developing countries. Myelitis is the most common manifestation of spinal tuberculosis. OBJECTIVE: we report the epidemiological characteristics, clinical and functional aspects in a group of 14 patients with tuberculous myelitis after functional rehabilitation. MATERIALS/PATIENTS AND METHODS: Over a period of 4 years, 14 cases of tuberculous myelitis were admitted for functional rehabilitation...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27670679/tuberculous-spondylitis-diagnosed-through-xpert-mtb-rif-assay-in-urine-a-case-report
#12
George Sikalengo, Adria Ramirez, Diana Faini, Kim Mwamelo, Manuel Battegay, Levan Jugheli, Christoph Hatz, Klaus Reither, Emilio Letang
BACKGROUND: Extrapulmonary tuberculosis (EPTB) is associated with high rates of morbidity and mortality. Diagnosis of EPTB is challenging in resource-limited settings due to difficulties in obtaining samples, as well as the paucibacillarity of the specimens. Skeletal tuberculosis accounts for 10-35 % of EPTB cases, with vertebral osteomyelitis (Pott's disease) representing 50 % of the cases. We present two cases of suspected Pott's disease, diagnosed through GeneXpert MTB/RIF assay in urine at a rural Tanzanian hospital...
September 26, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27587940/a-rare-complication-of-tuberculosis-acute-paraplegia
#13
Teoman Aydın, Özgür Taşpınar, Yasar Keskin, Müge Kepekçi, Meryem Güneşer, Adil Çamlı, Hakan Seyithanoğlu, Huriye Kızıltan, Ali Hikmet Eriş
BACKGROUND: Tuberculous radiculomyelitis(TBRM) is one of the complications of neurological tuberculosis and includes cases of arachnoiditis, intradural spinal tuberculoma or granuloma, and spinal cord complications of tuberculous meningitis (TBM). Here, we report a case of TBRM which presented with acute paraplegia. CASE DETAILS: Neurological examination on admission revealed flaccid paralysis, bilateral extensor plantar responses, and exaggerated deep tendon reflexes...
July 2016: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/27435619/spinal-tuberculosis-natural-history-of-disease-classifications-and-principles-of-management-with-historical-perspective
#14
REVIEW
Kush Kumar
PURPOSE: To describe the natural history spinal tuberculosis, classifications and principles of management based upon the grading of the neurological deficit. METHODS: Review of literature was conducted with the aim to provide the clinico-radiological correlation of the natural history of spinal tuberculosis in different stages. Management strategy is developed based upon the severity of the neurological deficit. RESULTS: A five stage natural history of spinal tuberculosis is described...
August 2016: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/27400225/treating-children-with-spinal-tuberculosis-via-debridement-with-allograft
#15
Z Guo, M Yao, J Wang, K Sun, Z Ji
Objective: This work aims to investigate the efficacy of debridement for paediatric thoracolumbar spinal tuberculosis (TB) by using the anterior approach and the allogeneic bone graft. Methods: The lesions of 16 children diagnosed with thoracolumbar spinal TB were exposed via the anterior approach. The pleura and peritoneum, granulation tissue, pus and dead bones of the TB, and the intervertebral disc with pathological changes and necrosis were completely eliminated...
December 10, 2015: West Indian Medical Journal
https://www.readbyqxmd.com/read/27166033/pathologic-lesions-in-children-with-acquired-immunodeficiency-syndrome-an-autopsy-study-of-11-cases-from-mumbai-india
#16
Dhanesheshwar N Lanjewar, Varsha Omprakash Bhatia, Sonali Dhaneshwar Lanjewar
BACKGROUND: Human immunodeficiency virus (HIV) infection in India has now been prevalent over three decades, and an increasing number of children are being affected with HIV. The spectrum of pathologic lesions in children with acquired immunodeficiency syndrome (AIDS) in India has not been well described. MATERIALS AND METHODS: A review of systematically conducted autopsies of 11 (10 boys and 1 girl) children with AIDS is presented. RESULTS: The mode of HIV transmission in 6 children was vertical; in one it was blood transfusion and in 4 children route was presumably vertical as these were children of orphanage...
April 2016: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/27163110/correlation-of-diffusion-tensor-imaging-parameters-with-neural-status-in-pott-s-spine
#17
Nikhil Jain, Namita Singh Saini, Sudhir Kumar, Mukunth Rajagopalan, Kanti Lal Chakraborti, Anil Kumar Jain
INTRODUCTION: Diffusion tensor imaging (DTI) has been used in cervical trauma and spondylotic myelopathy, and it has been found to correlate with neural deficit and prognosticate neural recovery. Such a correlation has not been studied in Pott's spine with paraplegia. Hence, this prospective study has been used to find correlation of DTI parameters with neural deficit in these patients. METHODS: Thirty-four patients of spinal TB were enrolled and DTI was performed before the start of treatment and after six months...
2016: SICOT-J
https://www.readbyqxmd.com/read/26994033/spinal-tuberculosis-with-paraplegia-in-pregnancy
#18
S Kaushal, S K Dora, S Thakur
Spinal tuberculosis leading to paraplegia is uncommon in pregnancy and is a diagnostic and therapeutic challenge. We report a case of tubercular paraplegia presenting at 35 weeks of gestation. She was managed with Anti-tubercular drugs and did not require surgical intervention. Her neurological status improved and she was allowed to go in labour. She delivered a healthy term infant by cesarean. At three months follow-up, both mother and child are doing well.
April 2015: JNMA; Journal of the Nepal Medical Association
https://www.readbyqxmd.com/read/26983410/one-stage-posterior-focus-debridement-interbody-graft-using-titanium-mesh-cages-posterior-instrumentation-and-fusion-in-the-surgical-treatment-of-lumbo-sacral-spinal-tuberculosis-in-the-aged
#19
Yu-Xiang Wang, Hong-Qi Zhang, Weiwei Liao, Ming-Xing Tang, Chao-Feng Guo, Ang Deng, Jian-Huang Wu, Jin-Yang Liu
PURPOSE: Aged patients represent a high risk group for acquiring spinal tuberculosis, and it still remains a leading cause of kyphosis and paraplegia in developing nations. Aged patients often combined with cardiovascular and respiratory disease and single lung ventilation via anterior approach surgery could result in more post-operative complications. We aimed to analyze the efficacy and feasibility of surgical management of aged patients with lumbo-sacral spine tuberculosis using one-stage posterior focus debridement, interbody graft using titanium mesh cages, posterior instrumentation, and fusion...
June 2016: International Orthopaedics
https://www.readbyqxmd.com/read/26894144/a-case-of-cervical-spine-tuberculosis-in-an-infant
#20
S N Singh, Trilok C Bhatt, Savit Kumar, Vikas Chauhan, Anjali Pandey
Tuberculosis of cervical spine is an extremely rare entity in infants with only few case reports available in the literature. The diagnosis is often delayed due to less dramatic effects of paraplegia or quadriplegia in an infant as compared to older paediatric population. Along with clinical and laboratory investigations, imaging plays a crucial role in defining the extent of involvement, evaluation of complications, providing suitable differential diagnosis and monitoring response to treatment. Tuberculosis typically involves the discovertebral complex while involvement of isolated vertebral body or multiple vertebrae without involving the intervertebral discs is much less common...
January 2016: Journal of Clinical and Diagnostic Research: JCDR
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