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https://www.readbyqxmd.com/read/29047445/transport-and-public-health-in-china-the-road-to-a-healthy-future
#1
REVIEW
Baoguo Jiang, Song Liang, Zhong-Ren Peng, Haozhe Cong, Morgan Levy, Qu Cheng, Tianbing Wang, Justin V Remais
Transportation-related risk factors are a major source of morbidity and mortality in China, where the expansion of road networks and surges in personal vehicle ownership are having profound effects on public health. Road traffic injuries and fatalities have increased alongside increased use of motorised transport in China, and accident injury risk is aggravated by inadequate emergency response systems and trauma care. National air quality standards and emission control technologies are having a positive effect on air quality, but persistent air pollution is increasingly attributable to a growing and outdated vehicle fleet and to famously congested roads...
October 14, 2017: Lancet
https://www.readbyqxmd.com/read/29046660/beyond-clinical-case-studies-in-psychoanalysis-a-review-of-psychoanalytic-empirical-single-case-studies-published-in-isi-ranked-journals
#2
REVIEW
Reitske Meganck, Ruth Inslegers, Juri Krivzov, Liza Notaerts
Single case studies are at the origin of both theory development and research in the field of psychoanalysis and psychotherapy. While clinical case studies are the hallmark of psychoanalytic theory and practice, their scientific value has been strongly criticized. To address problems with the subjective bias of retrospective therapist reports and uncontrollability of clinical case studies, systematic approaches to investigate psychotherapy process and outcome at the level of the single case have been developed...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29034166/post-lobotomy-epilepsy-illustrated-by-the-story-of-ellinor-hamsun-the-daughter-of-the-famous-norwegian-author-knut-hamsun
#3
Mia Tuft, Karl O Nakken
In Scandinavia, at least 11.500 people were lobotomized in the period 1939-1983. Beside grave personality changes, the surgery caused epilepsy in 10-35% of the patients. Moreover, many died due to perioperative bleedings, convulsive status epilepticus or SUDEP. Most of the stories of these people are anonymous and their post-lobotomy lives are scarcely documented. If it was not for the fact that Ellinor Hamsun (1916-1987) was the daughter of the famous Nobel Prize winning Norwegian author Knut Hamsun, her lobotomy story and the subsequent iatrogenic epilepsy would probably have remained unknown...
2017: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/29033855/implicit-recognition-of-familiar-and-unfamiliar-faces-in-schizophrenia-a-study-of-the-skin-conductance-response-in-familiarity-disorders
#4
Aurely Ameller, Aline Picard, Fabien D'Hondt, Guillaume Vaiva, Pierre Thomas, Delphine Pins
OBJECTIVE: Familiarity is a subjective sensation that contributes to person recognition. This process is described as an emotion-based memory-trace of previous meetings and could be disrupted in schizophrenia. Consequently, familiarity disorders could be involved in the impaired social interactions observed in patients with schizophrenia. Previous studies have primarily focused on famous people recognition. Our aim was to identify underlying features, such as emotional disturbances, that may contribute to familiarity disorders in schizophrenia...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29028880/semantic-memory-in-hiv-associated-neurocognitive-disorders-an-evaluation-of-the-cortical-versus-subcortical-hypothesis
#5
Savanna Tierney, Steven Paul Woods, Marizela Verduzco, Jessica Beltran, Paul J Massman, Rodrigo Hasbun
Objective: HIV-associated neurocognitive disorders (HAND) have historically been characterized as a subcortical condition that does not affect semantic memory; however, recent evidence suggests that the cortical regions that support semantic memory may be affected in HIV. Method: The current study examined the effects of HAND on semantic memory in 85 HIV+ individuals with HAND, 193 HIV+ individuals without HAND, and 181 HIV- individuals who completed the Boston Naming Test (BNT) and the Famous Faces subtest of the Kauffman Adolescent and Adult Intelligence Test (KAIT-FF)...
September 28, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/29028535/baicalin-and-its-metabolites-suppresses-gluconeogenesis-through-activation-of-ampk-or-akt-in-insulin-resistant-hepg-2-cells
#6
Tao Wang, Hongmei Jiang, Shijie Cao, Qian Chen, Mingyuan Cui, Zhijie Wang, Dandan Li, Jing Zhou, Tao Wang, Feng Qiu, Ning Kang
Scutellaria baicalensis Georgi (S. baicalensis), as a traditional Chinese herbal medicine, is an important component of several famous Chinese medicinal formulas for treating patients with diabetes mellitus. Baicalin (BG), a main bioactive component of S. baicalensis, has been reported to have antidiabetic effects. However, pharmacokinetic studies have indicated that BG has poor oral bioavailability. Therefore, it is hard to explain the pharmacological effects of BG in vivo. Interestingly, several reports show that BG is extensively metabolized in rats and humans...
September 23, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/29027276/natural-medicines-for-acute-renal-failure-a-review
#7
REVIEW
Motahareh Boozari, Hossein Hosseinzadeh
Acute renal failure (ARF) is a life-threating disease with high mortality percentage. Two important mechanisms of ARF are inflammation and oxidative stress. Plants are rich source of antioxidant compounds and have a strong anti-inflammatory activity, so they may be useful for the treatment of ARF. Some herbal medicines are effective against different models of experimentally induced ARF such as cisplatin, gentamicin, glycerol, and ischemia-reperfusion injury. Some of these plants such as ginseng, black seed, ginger, garlic, grape, pomegranate, saffron, and green tea are so famous and are effective against various models of ARF...
October 13, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29027246/medicinal-attributes-of-thienopyrimidine-based-scaffold-targeting-tyrosine-kinases-and-their-potential-anticancer-activities
#8
Amna Ghith, Nasser S M Ismail, Khairia Youssef, Khaled A M Abouzid
Thienopyrimidines (TP), comprising a thiophene ring fused with pyrimidine, are famous bioisosteres to purines, an essential part of the human metabolome. This scaffold has become an interesting structural element in the development of pharmaceutical compounds, due to their wide spectrum applications as cytotoxic agents against different types of human cancer cell lines, cGMP phosphodiesterase inhibitors, and anti-viral, anti-inflammatory, and anti-microbial agents. The structural similarity of this scaffold with adenine made it an excellent moiety to be used in the design of kinase inhibitors...
October 13, 2017: Archiv der Pharmazie
https://www.readbyqxmd.com/read/29023721/plant-phenolics-extraction-from-flos-chrysanthemi-response-surface-methodology-based-optimization-and-the-correlation-between-extracts-and-free-radical-scavenging-activity
#9
Yanfang Wu, Xinsheng Wang, Jintao Xue, Enguo Fan
Huaiju is one of the most famous and widely used Flos Chrysanthemi (FC) for medicinal purposes in China. Although various investigations aimed at phenolics extraction from other FC have been reported, a thorough optimization of the phenolics extraction conditions from Huaiju has not been achieved. This work applied the widely used response surface methodology (RSM) to investigate the effects of 3 independent variables including ethanol concentration (%), extraction time (min), and solvent-to-material ratio (mL/g) on the ultrasound-assisted extraction (UAE) of phenolics from FC...
October 12, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/29022634/the-anti-inflammatory-effect-of-agaricus-brasiliensis-is-partly-due-to-its-linoleic-acid-content
#10
Papawee Saiki, Yasuhiro Kawano, Leo J L D Van Griensven, Koyomi Miyazaki
For hundreds of years mushrooms have been used as functional food for health. The basidiomycete Agaricus brasiliensis (A. brasiliensis) is famous for the medicinal properties of its beta glucans and of its antioxidants. Most researchers have studied polysaccharides from A. brasiliensis for their anti-inflammatory activity. However, active compounds from this mushroom have not yet been studied for the inactivation of NO inhibitory activity. The present study aimed to find the active compounds from A. brasiliensis for their NO inhibitory activity related inflammatory activity...
October 12, 2017: Food & Function
https://www.readbyqxmd.com/read/29020749/the-draft-genome-assembly-of-rhododendron-delavayi-franch-var-delavayi
#11
Lu Zhang, Pengwei Xu, Yanfei Cai, Lulin Ma, Shifeng Li, Shufa Li, Weijia Xie, Jie Song, Lvchun Peng, Huijun Yan, Ling Zou, Yongpeng Ma, Chengjun Zhang, Qiang Gao, Jihua Wang
Rhododendron delavayi Franch. is globally famous as an ornamental plant. Its distribution in southwest China covers several different habitats and environments. However, not much research had been conducted on Rhododendron spp. at the molecular level, which hinders understanding of its evolution, speciation, and synthesis of secondary metabolites, as well as its wide adaptability to different environments. Here, we report the genome assembly and gene annotation of R. delavayi var. delavayi (the second genome sequenced in the Ericaceae), which will facilitate the study of the family...
October 1, 2017: GigaScience
https://www.readbyqxmd.com/read/29019960/molecular-insights-into-the-potential-insecticidal-interaction-of-%C3%AE-dihydroagarofuran-derivatives-with-the-h-subunit-of-v-atpase
#12
Jielu Wei, Ding Li, Xin Xi, Lulu Liu, Ximei Zhao, Wenjun Wu, Jiwen Zhang
Celangulin V (CV), one of dihydroagarofuran sesquiterpene polyesters isolated from Chinese bittersweet (Celastrus angulatus Maxim), is famous natural botanical insecticide. Decades of research suggests that is displays excellent insecticidal activity against some insects, such as Mythimna separata Walker. Recently, it has been validated that the H subunit of V-ATPase is one of the target proteins of the insecticidal dihydroagarofuran sesquiterpene polyesters. As a continuation of the development of new pesticides from these natural products, a series of β-dihydroagarofuran derivatives have been designed and synthesized...
October 11, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29016974/blockchain-distributed-ledger-technologies-for-biomedical-and-health-care-applications
#13
Tsung-Ting Kuo, Hyeon-Eui Kim, Lucila Ohno-Machado
Objectives: To introduce blockchain technologies, including their benefits, pitfalls, and the latest applications, to the biomedical and health care domains. Target Audience: Biomedical and health care informatics researchers who would like to learn about blockchain technologies and their applications in the biomedical/health care domains. Scope: The covered topics include: (1) introduction to the famous Bitcoin crypto-currency and the underlying blockchain technology; (2) features of blockchain; (3) review of alternative blockchain technologies; (4) emerging nonfinancial distributed ledger technologies and applications; (5) benefits of blockchain for biomedical/health care applications when compared to traditional distributed databases; (6) overview of the latest biomedical/health care applications of blockchain technologies; and (7) discussion of the potential challenges and proposed solutions of adopting blockchain technologies in biomedical/health care domains...
November 1, 2017: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/29016720/predicting-regulatory-compliance-in-beer-advertising-on-facebook
#14
Jonathan K Noel, Thomas F Babor
Aims: The prevalence of alcohol advertising has been growing on social media platforms. The purpose of this study was to evaluate alcohol advertising on Facebook for regulatory compliance and thematic content. Methods: A total of 50 Budweiser and Bud Light ads posted on Facebook within 1 month of the 2015 NFL Super Bowl were evaluated for compliance with a self-regulated alcohol advertising code and for thematic content. An exploratory sensitivity/specificity analysis was conducted to determine if thematic content could predict code violations...
August 30, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28994527/-advance-on-quality-control-of-toad-venom-and-its-key-influence-factors
#15
REVIEW
Zong-Yun Li, Ting Qu, Peng-Fei Wang, Liang-Mian Chen, Zhi-Min Wang, Hui-Min Gao
Toad venom (Chansu) is prepared from the dried secretion of Bufo bufo gargarizans or B. melanostictus. It is not only one of the famous and expensive traditional Chinese medicines(TCMs) from animal origin, but also one of 28 kinds of toxic TCMs to be required for special management issued by the State Council of the People's Republic of China. Chansu contains the rich bufadienolides and indole alkaloids, and displays various bioactivity including cardiotonic, anti-tumor, analgesia, and local anesthesia. Based on the published references in the recent years, the advance on the identification of adulterants and quality evaluation as well as the influence factors on the quality of toad venom was summarized to improve the quality standards and promote the level of quality control of toad venom and its preparations...
March 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28992542/de-novo-transcriptome-sequencing-of-camellia-sasanqua-and-the-analysis-of-major-candidate-genes-related-to-floral-traits
#16
Hui Huang, En-Hua Xia, Hai-Bin Zhang, Qiu-Yang Yao, Li-Zhi Gao
Camellia sasanqua is one of the most famous horticultural plants in Camellia (Theaceae) due to its aesthetic appeal as landscape plant. Knowledge regarding the genetic basis of flowering time, floral aroma and color in C. sasanqua is limited, but is essential to breed new varieties with desired floral traits. Here, we described the de novo transcriptome of young leaves, flower buds and flowers of C. sasanqua. A total of 60,127 unigenes were functionally annotated based on the sequence similarity. After analysis, we found that two floral integrator genes, SOC1 and AP1, in flowering time pathway showed evidence of gene family expansion...
September 1, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28991760/centenary-of-the-birth-of-academician-prof-dr-isak-tadzer-founder-of-the-pathophysiology-and-nuclear-medicine-in-macedonia
#17
Borislav Karanfilski
Academician Prof. Dr. Isak Tadzer was born a hundred years ago on December 24, 1916 in Sofia. He completed the primary and secondary education at the German College in Sofia. In 1935 he began his studies at the Medical Faculty in Vienna, which he had to stop because of the annexation of Austria to Germany in 1938. He returned to Bulgaria where he continued his studies and graduated from the Medical Faculty in Sofia in 1941. During the War, 1941-1944, he was forcedly mobilized and he worked as a doctor in several villages...
September 1, 2017: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://www.readbyqxmd.com/read/28991204/influence-of-plant-growth-retardants-on-quality-of-codonopsis-radix
#18
Yinyin Liao, Lanting Zeng, Pan Li, Tian Sun, Chao Wang, Fangwen Li, Yiyong Chen, Bing Du, Ziyin Yang
Plant growth retardant (PGR) refers to organics that can inhibit the cell division of plant stem tip sub-apical meristem cells or primordial meristem cell. They are widely used in the cultivation of rhizomatous functional plants; such as Codonopsis Radix, that is a famous Chinese traditional herb. However, it is still unclear whether PGR affects the medicinal quality of C. Radix. In the present study, amino acid analyses, targeted and non-targeted analyses by ultra-performance liquid chromatography combined with time-of-flight mass spectrometry (UPLC-TOF-MS) and gas chromatography-MS were used to analyze and compare the composition of untreated C...
October 9, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28989775/celebrating-30-years-of-science-from-the-james-clerk-maxwell-telescope
#19
REVIEW
Ian Robson, Wayne S Holland, Per Friberg
The James Clerk Maxwell Telescope (JCMT) has been the world's most successful single-dish telescope at submillimetre wavelengths since it began operations in 1987. From the pioneering days of single-element photometers and mixers, through to the state-of-the-art imaging and spectroscopic cameras, the JCMT has been associated with a number of major scientific discoveries. Famous for the discovery of 'SCUBA' galaxies, which are responsible for a large fraction of the far-infrared background, the JCMT has pushed the sensitivity limits arguably more than any other facility in this most difficult of wavebands in which to observe...
September 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28986776/most-of-it-started-with-t4-phage-and-was-then-taken-over
#20
REVIEW
Shigeki Takeda
Professor Fumio Arisaka is one of the famous leaders in bacteriophage research, especially in the areas of protein biophysics and structural biology. Autonomous phage morphogenesis is a self-assembly process controlled by subunit-subunit interaction. Under this principle, Fumio has studied T4 tail assembly and morphology. He has also contributed structural information about T4 phage through a combination of X-ray structural analysis and three-dimensional image reconstruction using cryo-electron microscopy. Most of the development of ultracentrifugation applications for molecular assembly and phage morphogenesis research was also performed in Fumio's laboratory...
October 6, 2017: Biophysical Reviews
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