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https://www.readbyqxmd.com/read/28421029/a-historical-view-of-motion-sickness-a-plague-at-sea-and-on-land-also-with-military-impact
#1
Doreen Huppert, Judy Benson, Thomas Brandt
Seasickness and its triggers, symptoms, and preventive measures were well known in antiquity. This chapter is based on an analysis of descriptions of motion sickness, in particular seasickness, in ancient Greek, Roman, and Chinese literature. A systematic search was made from the Greek period beginning with Homer in 800 BC to the late Roman period and ending with Aetios Amidenos in 600 AD, as well as in the Chinese medical classics dating from around 300 AD. Major aspects are the following: body movements caused by waves were identified in all cultures as the critical stimuli...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28415857/sharing-data-to-build-a-medical-information-commons-from-bermuda-to-the-global-alliance
#2
Robert Cook-Deegan, Rachel A Ankeny, Kathryn Maxson Jones
The Human Genome Project modeled its open science ethos on nematode biology, most famously through daily release of DNA sequence data based on the 1996 Bermuda Principles. That open science philosophy persists, but daily, unfettered release of data has had to adapt to constraints occasioned by the use of data from individual people, broader use of data not only by scientists but also by clinicians and individuals, the global reach of genomic applications and diverse national privacy and research ethics laws, and the rising prominence of a diverse commercial genomics sector...
April 17, 2017: Annual Review of Genomics and Human Genetics
https://www.readbyqxmd.com/read/28415847/synthesis-and-antitumour-activity-of-arctigenin-amino-acid-ester-derivatives-against-h22-hepatocellular-carcinoma
#3
Enbo Cai, Shijie Guo, Limin Yang, Mei Han, Jing Xia, Yan Zhao, Xiaorui Gao, Yu Wang
Arctigenin (ARG) is famous in its abundant pharmacological activity. However, many researches in it entered the bottleneck period because of its poor water solubility. The derivatives of ARG have been synthesised with five amino acids which have t-Butyloxy carbonyl (BOC) as a protective group. We examined the effects of removing BOC. The results showed that the amino acid derivatives without protective group have better water solubility and nitrite-clearing ability than ARG. Based on these results, ARG6' and ARG9' were selected at a dosage of 40 mg/kg to evaluate their antitumour activity...
April 18, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28406932/a-comparison-of-stimulus-types-in-online-classification-of-the-p300-speller-using-language-models
#4
William Speier, Aniket Deshpande, Lucy Cui, Nand Chandravadia, Dustin Roberts, Nader Pouratian
The P300 Speller is a common brain-computer interface communication system. There are many parallel lines of research underway to overcome the system's low signal to noise ratio and thereby improve performance, including using famous face stimuli and integrating language information into the classifier. While both have been shown separately to provide significant improvements, the two methods have not yet been implemented together to demonstrate that the improvements are complimentary. The goal of this study is therefore twofold...
2017: PloS One
https://www.readbyqxmd.com/read/28406712/reply-to-next-step-to-understand-subphenotypes-of-acute-respiratory-distress-syndrome
#5
Carolyn S Calfee, Kevin Delucchi, Katie R Famous
No abstract text is available yet for this article.
April 13, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28406664/spontaneous-retrieval-deficits-in-amnestic-mild-cognitive-impairment-a-case-of-focal-event-based-prospective-memory
#6
Agnieszka Niedźwieńska, Lia Kvavilashvili, Kunle Ashaye, Jacek Neckar
OBJECTIVE: Research on early cognitive markers of Alzheimer's disease is primarily focused on retrospective recall (of word lists, pairs of items, stories) and executive functions. However, research shows that people with amnestic mild cognitive impairment (aMCI), who are at a higher risk of developing the disease than healthy controls, are particularly impaired in remembering to do things in the future or prospective memory (PM). The aim of this study was to establish which type of event-based PM is particularly disrupted in aMCI, focal PM, based on spontaneous retrieval, or nonfocal PM that relies on strategic monitoring processes...
April 13, 2017: Neuropsychology
https://www.readbyqxmd.com/read/28405355/face-familiarity-promotes-stable-identity-recognition-exploring-face-perception-using-serial-dependence
#7
Rebecca Kok, Jessica Taubert, Erik Van der Burg, Gillian Rhodes, David Alais
Studies suggest that familiar faces are processed in a manner distinct from unfamiliar faces and that familiarity with a face confers an advantage in identity recognition. Our visual system seems to capitalize on experience to build stable face representations that are impervious to variation in retinal input that may occur due to changes in lighting, viewpoint, viewing distance, eye movements, etc. Emerging evidence also suggests that our visual system maintains a continuous perception of a face's identity from one moment to the next despite the retinal input variations through serial dependence...
March 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28400567/genetic-dissection-of-yield-traits-in-super-hybrid-rice-xieyou9308-using-both-unconditional-and-conditional-genome-wide-association-mapping
#8
Yingxin Zhang, Liyuan Zhou, Xihong Shen, Daibo Chen, Weixun Wu, Xiaodeng Zhan, Qunen Liu, Aike Zhu, Xiangyang Lou, Haiming Xu, Shihua Cheng, Liyong Cao
With the development and application of super rice breeding, elite rice hybrids with super high-yielding potential have been widely developed in last decades in China. Xieyou9308 is one of the most famous super hybrid rice varieties. To uncover the genetic mechanism of Xieyou9308's high yield potential, a recombinant inbred line (RIL) population derived from cross of XieqingzaoB and Zhonghui9308 was re-sequenced and investigated on the grain yield (GYD) and its three component traits, number of panicles per plant (NP), number of filled grains per panicle (NFGP), and grain weight (GW)...
April 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28397077/investigation-on-natural-resources-and-species-conservation-of-ophiocordyceps-sinensis-the-famous-medicinal-fungus-endemic-to-the-tibetan-plateau
#9
Wenjing Wang, Ke Wang, Xiaoliang Wang, Ruiheng Yang, Yi Li, Yijian Yao
No abstract text is available yet for this article.
April 10, 2017: Protein & Cell
https://www.readbyqxmd.com/read/28391367/an-updated-meta-analysis-of-the-ego-depletion-effect
#10
REVIEW
Junhua Dang
The ego depletion effect is one of the most famous phenomena in social psychology. A recent meta-analysis showed that after accounting for small-studies effects by using a newly developed method called PET-PEESE, the ego depletion effect was indistinguishable from zero. However, it is too early to draw such rushing conclusion because of the inappropriate usage of PET-PEESE. The current paper reported a stricter and updated meta-analysis of ego depletion by carefully inspecting problems in the previous meta-analysis, including new studies not covered by it, and testing the effectiveness of each depleting task...
April 8, 2017: Psychological Research
https://www.readbyqxmd.com/read/28387136/the-protective-effect-of-aucubin-from-eucommia-ulmoides-against-status-epilepticus-by-inducing-autophagy-and-inhibiting-necroptosis
#11
Jin Wang, Ying Li, Wei-Hua Huang, Xiang-Chang Zeng, Xiao-Hui Li, Jian Li, Jun Zhou, Jian Xiao, Bo Xiao, Dong-Sheng Ouyang, Kai Hu
Eucommia ulmoides Oliv. is a famous traditional Chinese medicine which exhibits anti-oxidative stress ability and neuro-protective effects. Aucubin is the predominant component of Eucommia ulmoides Oliv. Our present study is intended to investigate aucubin's potential protective effects on neurons against epilepsy in the hippocampus by establishing the lithium-pilocarpine induced status epilepticus (SE) rat model in vivo. Aucubin (at a low dose and a high dose of 5[Formula: see text]mg/kg and 10[Formula: see text]mg/kg, respectively) was administered through gavage for two weeks before lithium-pilocarpine injection...
April 7, 2017: American Journal of Chinese Medicine
https://www.readbyqxmd.com/read/28386857/reconstructing-the-recent-visual-past-hierarchical-knowledge-based-effects-in-visual-working-memory
#12
Marie Poirier, Daniel Heussen, Silvio Aldrovandi, Lauren Daniel, Saiyara Tasnim, James A Hampton
This paper presents two experiments that examine the influence of multiple levels of knowledge on visual working memory (VWM). Experiment 1 focused on memory for faces. Faces were selected from continua that were constructed by morphing two face photographs in 100 steps; half of the continua morphed a famous face into an unfamiliar one, while the other half used two unfamiliar faces. Participants studied six sequentially presented faces each from a different continuum, and at test they had to locate one of these within its continuum...
April 6, 2017: Psychonomic Bulletin & Review
https://www.readbyqxmd.com/read/28384605/simultaneous-quantification-of-11-active-constituents-in-shexiang-baoxin-pill-by-ultraperformance-convergence-chromatography-combined-with-tandem-mass-spectrometry
#13
Chao Lv, Liqing Chen, Peng Fu, Niao Yang, Qun Liu, Yongwei Xu, Qinglong Sun, Rui Li, Changsen Zhan, Weidong Zhang, Runhui Liu
On account of the complexity of chemical constituents of Shexiang Baoxin Pill (SBP), a famous traditional Chinese medicine (TCM) formula, a novel and effective UPC(2)-MS/MS method was developed to simultaneously determine the content of 11 active compounds of SBP with outstanding separation ability. Eleven components in SBP, including 2 ginsenosides, 2 bile acids, 3 bufadienolides and 4 volatiles were detected by electrospray ionization tandem mass spectrometry in positive and negative ion modes with multiple reaction monitor (MRM)...
March 31, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28379683/upon-the-shoulders-of-giants-open-source-hardware-and-software-in-analytical-chemistry
#14
Michael D M Dryden, Ryan Fobel, Christian Fobel, Aaron R Wheeler
Isaac Newton famously observed that "if I have seen further it is by standing on the shoulders of giants." We propose that this sentiment is a powerful motivation for the "open-source" movement in scientific research, in which creators provide everything needed to replicate a given project online, as well as providing explicit permission for users to use, improve, and share it with others. Here, we write to introduce analytical chemists who are new to the open-source movement to best practices and concepts in this area and to survey the state of open-source research in analytical chemistry...
April 5, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28377028/transurethral-incision-of-ureterocele-does-the-time-of-presentation-affect-the-need-for-further-surgical-interventions
#15
A Hodhod, R Jednak, J Khriguian, M El-Sherbiny
OBJECTIVES: Ureterocele management is considered to be one of the famous debates in pediatric urology. Despite some considering transurethral ureterocele incision (TUI) as a temporary line of treatment, others have reported good results in terms of being a definitive treatment. The present study evaluated the feasibility of TUI as a definitive line of management. Moreover, it studied the impact of presentation on the outcomes. PATIENTS AND METHODS: The charts of patients who had ureteroceles from 1995 to 2015 were retrospectively reviewed...
March 18, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28376689/a-nonmusician-with-severe-alzheimer-s-dementia-learns-a-new-song
#16
Amee Baird, Heidi Umbach, William Forde Thompson
The hallmark symptom of Alzheimer's Dementia (AD) is impaired memory, but memory for familiar music can be preserved. We explored whether a non-musician with severe AD could learn a new song. A 91 year old woman (NC) with severe AD was taught an unfamiliar song. We assessed her delayed song recall (24 hours and 2 weeks), music cognition, two word recall (presented within a familiar song lyric, a famous proverb, or as a word stem completion task), and lyrics and proverb completion. NC's music cognition (pitch and rhythm perception, recognition of familiar music, completion of lyrics) was relatively preserved...
February 2017: Neurocase
https://www.readbyqxmd.com/read/28373101/aptamer-delivery-of-sirna-radiopharmaceutics-and-chemotherapy-agents-in-cancer
#17
Carlos E B de Almeida, Lais Nascimento Alves, Enrique T Paulino, Januário Bispo Cabral-Neto, Sotiris Missailidis
Aptamers are oligonucleotide reagents with high affinity and specificity, which among other therapeutic and diagnostic applications have the capability of acting as delivery agents. Thus, aptamers are capable of carrying small molecules, nanoparticles, radiopharmaceuticals or fluorescent agents as well as nucleic acid therapeutics specifically to their target cells. In most cases, the molecules may possess interesting therapeutic properties, but their lack of specificity for a particular cell type, or ability to internalise in such a cell, hinders their clinical development, or cause unwanted side effects...
March 31, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28372598/semantic-memory-and-depressive-symptoms-in-patients-with-subjective-cognitive-decline-mild-cognitive-impairment-and-alzheimer-s-disease
#18
J Lehrner, G Coutinho, P Mattos, D Moser, M Pflüger, A Gleiss, E Auff, P Dal-Bianco, G Pusswald, E Stögmann
BACKGROUND: Semantic memory may be impaired in clinically recognized states of cognitive impairment. We investigated the relationship between semantic memory and depressive symptoms (DS) in patients with cognitive impairment. METHODS: 323 cognitively healthy controls and 848 patients with subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer's disease (AD) dementia were included. Semantic knowledge for famous faces, world capitals, and word vocabulary was investigated...
April 4, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28366102/new-putative-cryptic-species-detection-and-genetic-network-analysis-of-bemisia-tabaci-hempitera-aleyrodidae-in-china-based-on-mitochondrial-coi-sequences
#19
Jian Hu, Xiaoyun Zhang, Zhilin Jiang, Feifei Zhang, Yuanyuan Liu, Zhan Li, Zhongkai Zhang
The whitefly Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae) is a cryptic species complex and widely distributed throughout tropical and subtropical regions. To understand the B. tabaci cryptic species diversity in China more comprehensively, in the year 2014 and 2016, a large-scale sampling was conducted from the famous biodiversity hotspot of China, Yunnan province. Mitochondrial cytochrome oxidase I gene sequences were used to identify new putative cryptic species. Phylogenetic analyses were performed using Bayesian methods to evaluate the position of new cryptic species in the context of the B...
April 1, 2017: Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis
https://www.readbyqxmd.com/read/28364366/a-new-tool-using-bird-to-crow-about
#20
Natalie Uomini, Gavin Hunt
The Hawaiian crow has been revealed as a skilled tool user, confirmed by testing the last members of this endangered species that survive in captivity. The finding suggests its behavior is tantalizingly similar to that of the famous tool-using New Caledonian crow and has implications for the evolution of tool use and intelligence in birds.
March 31, 2017: Learning & Behavior
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