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https://www.readbyqxmd.com/read/28544870/the-killing-of-kitty-genovese-what-else-does-this-case-tell-us
#1
Saul M Kassin
Well known in popular culture, the 1964 murder of Kitty Genovese in Queens, New York, became famous because not one of an alleged 38 bystanders called police until it was too late. Within psychology, this singular event inspired the study of bystander intervention. With the spotlight of history focused on Ms. Genovese and bystanders, other events, also profound for what they tell us about human social behavior, have escaped public notice. Based on archival records and current interviews, this article describes the three issues linked to Genovese...
May 2017: Perspectives on Psychological Science: a Journal of the Association for Psychological Science
https://www.readbyqxmd.com/read/28535929/genetic-coding-and-united-hypercomplex-systems-in-the-models-of-algebraic-biology
#2
REVIEW
Sergey V Petoukhov
Structured alphabets of DNA and RNA in their matrix form of representations are connected with Walsh functions and a new type of systems of multidimensional numbers. This type generalizes systems of complex numbers and hypercomplex numbers, which serve as the basis of mathematical natural sciences and many technologies. The new systems of multi-dimensional numbers have interesting mathematical properties and are called in a general case as "systems of united-hypercomplex numbers" (or briefly "U-hypercomplex numbers")...
May 20, 2017: Bio Systems
https://www.readbyqxmd.com/read/28534819/ginsenoside-rb2-alleviates-hepatic-lipid-accumulation-by-restoring-autophagy-via-induction-of-sirt1-and-activation-of-ampk
#3
Qi Huang, Ting Wang, Liu Yang, He-Yao Wang
Although Panax ginseng is a famous traditional Chinese medicine and has been widely used to treat a variety of metabolic diseases including hyperglycemia, hyperlipidemia, and hepatosteatosis, the effective mediators and molecular mechanisms remain largely unknown. In this study we found that ginsenoside Rb2, one of the major ginsenosides in Panax ginseng, was able to prevent hepatic lipid accumulation through autophagy induction both in vivo and in vitro. Treatment of male db/db mice with Rb2 significantly improved glucose tolerance, decreased hepatic lipid accumulation, and restored hepatic autophagy...
May 19, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28528730/sir-charles-bell-unheralded-laryngologist
#4
Elliot Abemayor
INTRODUCTION: Sir Charles Bell is renowned and revered as an outstanding surgeon, anatomist, clinician and teacher and his many contributions to various medical fields have been amply described. What are less well-known are his contributions to the field of laryngology. METHODS: Selected clinical and physiological publications by Bell were examined that addressed issues related specifically to the airway or pharynx. These included both case reports and case series...
April 21, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28528032/a-surprising-alliance-two-giants-of-the-20th-century
#5
Robert M Sade
Alexis Carrel and Charles Lindbergh were among the most famous international figures in the 20th century: Carrel, the surgeon-scientist who won a Nobel prize as a young surgeon, and Lindbergh, the aviator-engineer who pioneered aviation and promoted commercial flight throughout his life. Surprisingly, these two amazing individuals came together to collaborate on the early development of extracorporeal circulation. Their work was interrupted by the onset of World War II, which destroyed one of them and nearly destroyed the other...
June 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28527508/social-media-and-web-presence-for-patients-and-professionals-evolving-trends-and-implications-for-practice
#6
REVIEW
Jose E Barreto, Curtis L Whitehair
The use of social media has become very instinctive to many. It has become part of a daily routine. Enhanced communication, liberated expressions of self, becoming updated with all the trends and news, and marketing promotion are only some of the reasons why most people use social media. Health care providers including physicians should take advantage of these platforms for professional purposes. Social media extends far beyond the famous platforms such as Facebook, Twitter, Pinterest, and Instagram, used mostly for social connections...
May 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28521385/-ziziphus-oxyphylla-ethnobotanical-ethnopharmacological-and-phytochemical-review
#7
REVIEW
Rizwan Ahmad, Niyaz Ahmad, Atta Abbas Naqvi
ETHNOPHARMACOLOGICAL RELEVANCE: Ziziphus oxyphylla (ZO) is distributed mainly in tropic and warm temperate regions in the world. Pakistan owns six (06) indigenous species of genus Ziziphus out of which ZO is widely used for traditional treatment of different ailments such as diabetes, jaundice and liver diseases. AIM OF THE STUDY: The present review aims to provide in-depth and comprehensive literature overview, regarding botanical, chemical and biological characteristics of the plant alongwith phytochemical isolation and mechanistic studies to support its folklore and traditional uses...
May 14, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28515769/inhibitory-effects-of-different-fractions-of-nepeta-satureioides-on-melanin-synthesis-through-reducing-oxidative-stress
#8
Seyed Ahmad Emami, Rezvan Yazdian-Robati, Mohammad Sadeghi, Javad Baharara, Elaheh Amini, Farzaneh Salek, Zahra Tayarani-Najaran
Nepeta satureioides Boiss. has been used in traditional medicine of eastern countries and is famous for its medicinal properties. The aim of this study was to evaluate the effect of methanol (MeOH), n-hexane and dichloromethane (CH2Cl2) fractions of the extract on melanin synthesis and oxidative stress in B16F10 melanoma cell line. The B16F10 cell line viability after treatment with increasing concentrations of different fractions of the plant (5-60 μg/mL) was measured using MTT assay. The inhibitory effect on synthesis of melanin, mushroom tyrosinase activity, cellular tyrosinase and oxidative stress were determined by the colorimetric and fluorometric methods...
April 2017: Research in Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28515626/the-history-of-tuberculosis-from-the-first-historical-records-to-the-isolation-of-koch-s-bacillus
#9
REVIEW
I Barberis, N L Bragazzi, L Galluzzo, M Martini
Tuberculosis (TB) is a contagious, infectious disease, due to Mycobacterium tuberculosis (MT) that has always been a permanent challenge over the course of human history, because of its severe social implications. It has been hypothesized that the genus Mycobacterium originated more than 150 million years ago. In the Middle Ages, scrofula, a disease affecting cervical lymph nodes, was described as a new clinical form of TB. The illness was known in England and France as "king's evil", and it was widely believed that persons affected could heal after a royal touch...
March 2017: Journal of Preventive Medicine and Hygiene
https://www.readbyqxmd.com/read/28513568/using-uplc-ms-ms-for-characterization-of-active-components-in-extracts-of-yupingfeng-and-application-to-a-comparative-pharmacokinetic-study-in-rat-plasma-after-oral-administration
#10
COMPARATIVE STUDY
Meng-Qi Jia, Ye-Juan Xiong, Yun Xue, Yan Wang, Chao Yan
Yupingfeng (YPF), a famous traditional Chinese medicine, which contains a large array of compounds, has been effectually used in health protection. A two-dimensional liquid chromatography (²D-LC) combined with quadrupole time-of-flight mass spectrometry (QTOF-MS) method was firstly established to separate and identify chemical components in YPF. A total of 33 compounds were identified, including 15 constituents (flavonoids and saponins) in Astragali radix; seven constituents (sesquiterpenoids and polysaccharide) in Atractylodis rhizoma; and 11 constituents (chromone and coumarins) in Saposhnikoviae radix...
May 17, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28506863/the-null-test-for-peptide-identification-algorithm-in-shotgun-proteomics
#11
Shu-Rong Zhang, Yi-Chu Shan, Hao Jiang, Jian-Hui Liu, Yuan Zhou, Li-Hua Zhang, Yu-Kui Zhang
The present research proposed general evaluation strategy named Null-Test for peptide identification algorithm in Shotgun proteomics. The Null-Test method based on random matching can be utilized to check whether the algorithm has a tendency to make a mistake or has potential bugs, faultiness, errors etc., and to validate the reliability of the identification algorithm. Unfortunately, none of the five famous identification software could pass the most stringent Null-Test. PatternLab had good performance in both Null-Test and routine search by making a good control on the overfitting with sound design...
May 12, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/28506806/selective-associative-phonagnosia-after-right-anterior-temporal-stroke
#12
Simona Luzzi, Michela Coccia, Gabriele Polonara, Carlo Reverberi, Gabriella Ceravolo, Mauro Silvestrini, Fabio Fringuelli, Sara Baldinelli, Leandro Provinciali, Guido Gainotti
We report the case of a 48 year old men who developed a selective impairment in famous voice recognition after ischemic stroke in right subcortical structures (lenticular nucleus and head of the caudate) and right anterior temporal lobe. He underwent fibrinolytic treatment. During the following days he progressively recovered and was discharged without neurological focal sign. Patent foramen ovale was found. When he got back to his house he noticed that he was unable to recognize the voice of his favoured singers and needed to ask who was the singer to his relatives...
May 12, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28506496/twins-labeling-liquid-chromatography-mass-spectrometry-based-metabolomics-for-absolute-quantification-of-tryptophan-and-its-key-metabolites
#13
Huimin Guo, Yu Jiao, Xu Wang, Tao Lu, Zunjian Zhang, Fengguo Xu
Tryptophan metabolism plays a crucial role in mediating gastrointestinal function. Here, in order to absolutely quantify tryptophan and its metabolites, a liquid chromatography-mass spectrometry (LC-MS) based targeted metabolomics approach was developed using N-dimethyl-/N-diethyl-amino naphthalene-1-sulfonyl chloride (Dns/Dens-Cl) as twins labeling (TL) reagents. Dns-Cl is famous in amine and phenol derivations, and structure is similar with Dens-Cl. The introduction of easily protonated moiety of tertiary ammonium-containing part in the derivatives from Dns to tryptophan and its metabolites not only improved the LC separation but also enhanced their MS response...
May 5, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28504815/the-arago-laboratory-of-banyuls-and-some-of-its-academicians
#14
Marie-Odile Soyer-Gobillard
Since its founding in 1881 by Henri de Lacaze-Duthiers (1821-1901), the Arago Laboratory of Banyuls has been one of the three marine stations of the University Pierre and Marie Curie-Paris 6. It is located in Banyuls (Banyuls-sur-Mer) in Northern Catalonia. The center hosts researchers and students from all over the world. Some became famous, including four Nobel Prize winners: André Lwoff (1965), Pierre-Gilles de Gennes (1991), Albert Fert (2007) and Jules Hoffmann (2011). This article focuses on five scientists closely related to the center...
December 2016: International Microbiology: the Official Journal of the Spanish Society for Microbiology
https://www.readbyqxmd.com/read/28503371/transcriptome-sequencing-and-snp-detection-in-phoebe-chekiangensis
#15
Bing He, Yingang Li, Zhouxian Ni, Li-An Xu
BACKGROUND: Phoebe chekiangensis is a rare tree species that is only distributed in south-eastern China. Although this species is famous for its excellent wood properties, it has not been extensively studied at the molecular level. RESULTS: Here, the transcriptome of P. chekiangensis was sequenced using next-generation sequencing technology, and 75,647 transcripts with 48,011 unigenes were assembled and annotated. In addition, 162,938 putative single nucleotide polymorphisms (SNPs) were predicted and 25 were further validated using the Sanger method...
2017: PeerJ
https://www.readbyqxmd.com/read/28498054/first-clinical-use-of-stereotaxy-in-humans-the-key-role-of-x-ray-localization-discovered-by-gaston-contremoulins
#16
Pierre Bourdillon, Caroline Apra, Marc Lévêque
Although attempts to develop stereotactic approaches to intracranial surgery started in the late 19th century with Dittmar, Zernov, and more famously, Horsley and Clarke, widespread use of the technique for human brain surgery started in the second part of the 20th century. Remarkably, a significant similar surgical procedure had already been performed in the late 19th century by Gaston Contremoulins in France and has remained unknown. Contremoulins used the principles of modern stereotaxy in association with radiography for the first time, allowing the successful removal of intracranial bullets in 2 patients...
May 12, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28497214/comparative-theoretical-studies-of-differently-bridged-nitramino-substituted-ditetrazole-2-n-oxides-with-high-detonation-performance-and-an-oxygen-balance-of-around-zero
#17
Qiong Wu, Bo Kou, Zusheng Hang, Weihua Zhu
In this work, six (A-F) nitramino (-NHNO2)-substituted ditetrazole 2-N-oxides with different bridging groups (-CH2-, -CH2-CH2-, -NH-, -N=N-, and -NH-NH-) were designed. The six compounds were based on the parent compound tetrazole 2-N-oxide, which possesses a high oxygen balance and high density. The structure, heat of formation, density, detonation properties (detonation velocity D and detonation pressure P), and the sensitivity of each compound was investigated systematically via density functional theory, by studying the electrostatic potential, and using molecular mechanics...
June 2017: Journal of Molecular Modeling
https://www.readbyqxmd.com/read/28495701/poor-human-olfaction-is-a-19th-century-myth
#18
REVIEW
John P McGann
It is commonly believed that humans have a poor sense of smell compared to other mammalian species. However, this idea derives not from empirical studies of human olfaction but from a famous 19th-century anatomist's hypothesis that the evolution of human free will required a reduction in the proportional size of the brain's olfactory bulb. The human olfactory bulb is actually quite large in absolute terms and contains a similar number of neurons to that of other mammals. Moreover, humans have excellent olfactory abilities...
May 12, 2017: Science
https://www.readbyqxmd.com/read/28494685/greek-surgeon-pavlos-ioannou-s-possible-influence-on-william-halsted-s-famous-radical-mastectomy
#19
Gregory Tsoucalas, Lazaros Vladimiros, Markos Sgantzos
Pavlos Ioannou performed an innovative surgical operation for breast cancer in Vienna University Hospital in 1861. A few years later, after his return to Greece, an operation performed on his closest friend's child, which led to fatal complications, led him to retire from surgical practice. William Halsted travelled to Europe in order to master European surgery, including at Vienna University, and about 20 years later he published his famous method for radical mastectomy, which appears to be identical to Ioannou's operation...
May 1, 2017: Surgical Innovation
https://www.readbyqxmd.com/read/28494313/heavy-metals-translocation-and-accumulation-from-the-rhizosphere-soils-to-the-edible-parts-of-the-medicinal-plant-fengdan-paeonia-ostii-grown-on-a-metal-mining-area-china
#20
Zhang Jun Shen, De Cong Xu, Yan Song Chen, Zhen Zhang
Fengdan (Paeonia ostii) is one of Chinese 34 famous medicinal materials. This study investigated the concentrations of Arsenic (As), Chromium (Cr), Cadmium (Cd), Copper (Cu), Lead (Pb), Iron (Fe), Manganese (Mn), and Zinc (Zn) in rhizosphere soils, cortex mouton and seeds of Fengdan planted in a metal mining area, China. The mean concentrations of As, Cd, Cu, and Zn in the rhizosphere soils were above the limits set by the Chinese Soil Environmental Quality Standard (GB 15618-1995). The contamination factor (CF) of Cd was >5, while it was >2for As, Cu, Pb, and Zn in all the soils...
May 8, 2017: Ecotoxicology and Environmental Safety
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