Zenghu Zhang, Dehai Li, Ruize Xie, Ruoyu Guo, Shailesh Nair, Huan Han, Guojian Zhang, Qun Zhao, Lihua Zhang, Nianzhi Jiao, Yongyu Zhang
Algae and bacteria have complex and intimate interactions in the ocean. Besides mutualism, bacteria have evolved a variety of molecular-based anti-algal strategies. However, limited by the unknown mechanism of synthesis and action of these molecules, these strategies and their global prevalence remain unknown. Here we identify a novel strategy through which a marine representative of the Gammaproteobacteria produced 3,3',5,5'-tetrabromo-2,2'-biphenyldiol (4-BP), that kills or inhibits diverse phytoplankton by inhibiting plastoquinone synthesis and its effect cascades to many other key metabolic processes of the algae...
September 8, 2023: ISME Journal