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liquen oral

R A Melo, L A B Silva, A N Fernades-Costa, B V B Monteiro, E J D Silveira, M C C Miguel
Lichen planus is a chronic noninfectious inflammatory mucocutaneous disease that affects the skin, nails and mucosae, including the oral mucosa.1 Although the etiology of oral liquen planus (OLP) remains not fully elucidated, it is recognized that its pathogenesis arises from an immune-mediated response and many authors suggest the disease to be an autoimmune process.2-5 Despite the high prevalence and well-defined cytotoxic activity of CD8+ T lymphocytes against keratinocytes of the basal layer of the epithelium in OLP, helper CD4+ T lymphocytes also play an important role in the pathogenesis of this disease...
January 5, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
Luís Carlos Spolidorio, Vinícius Rangel Martins, Ruchele Dias Nogueira, Denise Madalena Spolidorio
Candidosis is the most common fungal infection in the oral cavity, and is usually associated with local and systemic predisposing factors. The occurrence and relevance of Candidal infection in oral lesions such as liquen planus, leukoplakias and carcinomas are still to be understood. The aim of the present study was to define the frequency of infection by Candida sp. on biopsies of oral mucosal lesions and associate its presence with malignant and dysplastic lesions. Histopathology reports issued between 1990 and 2001 inclusive were reviewed...
January 2003: Pesquisa Odontológica Brasileira, Brazilian Oral Research
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