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https://www.readbyqxmd.com/read/28749159/hierarchical-exploratory-factor-analyses-of-the-woodcock-johnson-iv-full-test-battery-implications-for-chc-application-in-school-psychology
#1
Stefan C Dombrowski, Ryan J McGill, Gary L Canivez
The Woodcock-Johnson (fourth edition; WJ IV; Schrank, McGrew, & Mather, 2014a) was recently redeveloped and retains its linkage to Cattell-Horn-Carroll theory (CHC). Independent reviews (e.g., Canivez, 2017) and investigations (Dombrowski, McGill, & Canivez, 2017) of the structure of the WJ IV full test battery and WJ IV Cognitive have suggested the need for additional factor analytic exploration. Accordingly, the present study used principal axis factoring (PAF) followed by the Schmid and Leiman (SL; Schmid & Leiman, 1957) procedure with the 2 school-aged correlation matrices from the normative sample to determine the degree to which the WJ IV total battery structure could be replicated...
July 27, 2017: School Psychology Quarterly
https://www.readbyqxmd.com/read/28748933/spontaneous-breaking-of-rotational-symmetry-in-copper-oxide-superconductors
#2
J Wu, A T Bollinger, X He, I Božović
The origin of high-temperature superconductivity in copper oxides and the nature of the 'normal' state above the critical temperature are widely debated. In underdoped copper oxides, this normal state hosts a pseudogap and other anomalous features; and in the overdoped materials, the standard Bardeen-Cooper-Schrieffer description fails, challenging the idea that the normal state is a simple Fermi liquid. To investigate these questions, we have studied the behaviour of single-crystal La2-xSrxCuO4 films through which an electrical current is being passed...
July 26, 2017: Nature
https://www.readbyqxmd.com/read/28748912/a-novel-allosteric-site-in-casein-kinase-2%C3%AE-discovered-using-combining-bioinformatics-and-biochemistry-methods
#3
Hai-Ming Jiang, Jiang-Kai Dong, Kun Song, Tong-Dan Wang, Wen-Kang Huang, Jing-Miao Zhang, Xiu-Yan Yang, Ying Shen, Jian Zhang
Casein kinase 2 (CK2) is a highly pleiotropic serine-threonine kinase, which catalyzed phosphorylation of more than 300 proteins that are implicated in regulation of many cellular functions, such as signal transduction, transcriptional control, apoptosis and the cell cycle. On the other hand, CK2 is abnormally elevated in a variety of tumors, and is considered as a promising therapeutic target. The currently available ATP-competitive CK2 inhibitors, however, lack selectivity, which has impeded their development in cancer therapy...
July 27, 2017: Acta Pharmacologica Sinica
https://www.readbyqxmd.com/read/28748648/accurate-template-based-modelling-in-casp12-using-the-intfold4-ts-modfold6-and-refold-methods
#4
Liam J McGuffin, Ahmad N Shuid, Robert Kempster, Ali H A Maghrabi, John O Nealon, Bajuna R Salehe, Jennifer D Atkins, Daniel B Roche
Our aim in CASP12 was to improve our Template Based Modelling (TBM) methods through better model selection, accuracy self-estimate (ASE) scores and refinement. To meet these aims we developed two new automated methods, which we used to score, rank and improve upon the provided server models. Firstly, the ModFOLD6_rank method, for improved global Quality Assessment (QA), model ranking and the detection of local errors. Secondly, the ReFOLD method for fixing errors through iterative QA guided refinement. For our automated predictions we developed the IntFOLD4-TS protocol, which integrates the ModFOLD6_rank method for scoring the multiple-template models that were generated using a number of alternative sequence-structure alignments...
July 27, 2017: Proteins
https://www.readbyqxmd.com/read/28747833/identification-of-pork-adulteration-in-processed-meat-products-using-the-developed-mitochondrial-dna-based-primers
#5
Jimyeong Ha, Sejeong Kim, Jeeyeon Lee, Soomin Lee, Heeyoung Lee, Yukyung Choi, Hyemin Oh, Yohan Yoon
The identification of pork in commercially processed meats is one of the most crucial issues in the food industry because of religious food ethics, medical purposes, and intentional adulteration to decrease production cost. This study therefore aimed to develop a method for the detection of pork adulteration in meat products using primers specific for pig mitochondrial DNA. Mitochondrial DNA sequences for pig, cattle, chicken, and sheep were obtained from GenBank and aligned. The 294-bp mitochondrial DNA D-loop region was selected as the pig target DNA sequence and appropriate primers were designed using the MUSCLE program...
2017: Korean Journal for Food Science of Animal Resources
https://www.readbyqxmd.com/read/28747795/tricritical-point-from-high-field-magnetoelastic-and-metamagnetic-effects-in-un
#6
K Shrestha, D Antonio, M Jaime, N Harrison, D S Mast, D Safarik, T Durakiewicz, J-C Griveau, K Gofryk
Uranium nitride (UN) is one of the most studied actinide materials as it is a promising fuel for the next generation of nuclear reactors. Despite large experimental and theoretical efforts, some of the fundamental questions such as degree of 5 f-electron localization/delocalization and its relationship to magneto-vibrational properties are not resolved yet. Here we show that the magnetostriction of UN measured in pulsed magnetic fields up to 65 T and below the Néel temperature is large and exhibits complex behavior with two transitions...
July 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28747783/engineering-the-geometrical-shape-of-mesenchymal-stromal-cells-through-defined-cyclic-stretch-regimens
#7
Brandan Walters, Tatiana Uynuk-Ool, Miriam Rothdiener, Julian Palm, Melanie L Hart, Jan P Stegemann, Bernd Rolauffs
Stem cells have been predicted to improve disease outcomes and patient lives. Steering stem cell fate - through controlling cell shape - may substantially accelerate progress towards this goal. As mesenchymal stromal cells (MSCs) are continuously exposed in vivo to a dynamically changing biomechanical environment, we hypothesized that exogenous forces can be applied for engineering a variety of significantly different MSC shapes. We applied specific cyclic stretch regimens to human MSCs and quantitatively measured the resulting cell shape, alignment, and expression of smooth muscle (SMC) differentiation markers, as those have been associated with elongated morphology...
July 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28747440/aligned-fibers-direct-collective-cell-migration-to-engineer-closing-and-non-closing-wound-gaps
#8
Puja Sharma, Colin Ng, Aniket Jana, Abinash Padhi, Paige Szymanski, Jerry S H Lee, Bahareh Behkam, Amrinder S Nain
Cell emergence onto damaged or organized fibrous extracellular matrix (ECM) is a crucial precursor to collective cell migration in wound closure and cancer metastasis, respectively. However, there is a fundamental gap in our quantitative understanding of the role of local ECM size and arrangement in cell emergence based migration and local gap closure. Here, using ECM-mimicking nanofibers bridging cell monolayers, we describe a method to recapitulate and quantitatively describe these in vivo behaviors over multi spatial (single cell to cell sheets) and temporal (minutes-weeks) scales...
July 26, 2017: Molecular Biology of the Cell
https://www.readbyqxmd.com/read/28747258/confidence-and-clinical-judgement-in-community-nurses-managing-venous-leg-ulceration-a-judgement-analysis
#9
Una J Adderley, Carl Thompson
BACKGROUND: The variation in the management of venous leg ulceration in the UK is partly attributable to an uncertain clinical environment but the quality of judgements is influenced by the how well nurses' confidence and accuracy are aligned. OBJECTIVES: To assess UK community nurses' confidence in the accuracy of their diagnostic judgements and treatment choices when managing venous leg ulceration. DESIGN: Judgement Analysis. SETTING: UK community and primary care nursing services...
July 19, 2017: Journal of Tissue Viability
https://www.readbyqxmd.com/read/28747043/hydrothermal-synthesis-of-in2o3-nanoparticles-hybrid-twins-hexagonal-disk-zno-heterostructures-for-enhanced-photocatalytic-activities-and-stability
#10
Hairui Liu, Haifa Zhai, Chunjie Hu, Jien Yang, Zhiyong Liu
In2O3 nanoparticles hybrid twins hexagonal disk (THD) ZnO with different ratios were fabricated by a hydrothermal method. The as-obtained ZnO/In2O3 composites are constituted by hexagonal disks ZnO with diameters of about 1 μm and In2O3 nanoparticles with sizes of about 20-50 nm. With the increase of In2O3 content in ZnO/In2O3 composites, the absorption band edges of samples shifted from UV to visible light region. Compared with pure ZnO, the ZnO/In2O3 composites show enhanced photocatalytic activities for degradation of methyl orange (MO) and 4-nitrophenol (4-NP) under solar light irradiation...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28746933/androgen-regulates-dimorphic-f-actin-assemblies-in-the-genital-organogenesis
#11
Liqing Liu, Kentaro Suzuki, Eunice Chun, Aki Murashima, Yuki Sato, Naomi Nakagata, Toshihiko Fujimori, Shigenobu Yonemura, Wanzhong He, Gen Yamada
Impaired androgen activity induces defective sexual differentiation of the male reproductive tract, including hypospadias, an abnormal formation of the penile urethra. Androgen signaling in the urethral mesenchyme cells (UMCs) plays essential roles in driving dimorphic urethral development. However, cellular events for sexual differentiation remain virtually unknown. In this study, histological analyses, fluorescent staining, and transmission electron microscopy (TEM) were performed to reveal the cellular dimorphisms of UMCs...
July 27, 2017: Sexual Development: Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation
https://www.readbyqxmd.com/read/28746401/identification-of-one-b-cell-epitope-from-ns1-protein-of-duck-tembusu-virus-with-monoclonal-antibodies
#12
Jinfeng Ti, Zhijie Li, Xiuli Li, Yunjian Lu, Youxiang Diao, Fang Li
This study describes the identification of one linear B-cell epitope on TMUV NS1 protein with monoclonal antibody (mAb) 3G2 by indirect enzyme-linked immunosorbent assay (ELISA). In this study, NS1 protein was expressed in prokaryotic expression system and purified. One mAb against NS1 protein was generated from Balb/c mice immunized with recombinant protein NS1. A set of 35 partially-overlapping polypeptides covering the entire NS1 protein was expressed with PGEX-6P-1 vector and screened with mAb 3G2. One polypeptide against the mAb was acquired and identified by indirect ELISA and western-blot...
2017: PloS One
https://www.readbyqxmd.com/read/28746136/using-organizational-philosophy-to-create-a-self-sustaining-compensation-plan-without-harming-academic-missions
#13
Robert Leverence, Richard Nuttall, Rachel Palmer, Mark Segal, Alicia Wood, Fay Yancey, Jonathon Shuster, Mark Brantly, Robert Hromas
PROBLEM: Academic physician reimbursement has moved to productivity-based compensation plans. To be sustainable, such plans must be self-funding. Additionally, unless research and education are appropriately valued, faculty involved in these efforts will become disillusioned, yet revenue generation in these activities is less robust than for clinical care activities. APPROACH: Faculty at the Department of Medicine, University of Florida Health, elected a committee of junior and senior faculty and division chiefs to restructure the compensation plan in fiscal year (FY) 2011...
August 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28746127/dysphagia-after-occipitothoracic-fusion-is-caused-by-direct-compression-of-oropharyngeal-space-due-to-anterior-protrusion-of-mid-cervical-spine
#14
Shuichi Kaneyama, Masatoshi Sumi, Koichi Kasahara, Aritetsu Kanemura, Masato Takabatake, Tomonori Yano
STUDY DESIGN: This was a retrospective study. OBJECTIVE: To investigate the relationship among the craniocervical alignment, the oropharyngeal space, and the incidence of dysphagia after occipitothoracic fusion (OTF). SUMMARY OF BACKGROUND DATA: Craniocervical malalignment after OTF is one of a trigger of dysphagia. However, there has been no logical explanation for the etiology yet. METHODS: A total of 32 patients who underwent OTF (5 male, 27 female) were reviewed...
August 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28746124/a-japanese-stretching-intervention-can-modify-lumbar-lordosis-curvature
#15
Norio Kadono, Kazushi Tsuchiya, Azusa Uematsu, Hiroshi Kamoshita, Kazunori Kiryu, Tibor Hortobágyi, Shuji Suzuki
STUDY DESIGN: Eighteen healthy male adults were assigned to either an intervention or control group. OBJECTIVES: Isogai dynamic therapy (IDT) is one of Japanese stretching interventions and has been practiced for over 70 years. However, its scientific quantitative evidence remains unestablished. The objective of this study was to determine whether IDT could modify lumbar curvature in healthy young adults compared with stretching exercises used currently in clinical practice...
August 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28746123/a-change-in-lumbar-sagittal-alignment-after-single-level-anterior-lumbar-interbody-fusion-for-lumbar-degenerative-spondylolisthesis-with-normal-sagittal-balance
#16
Chi Heon Kim, Chun Kee Chung, Sung Bae Park, Seung Heon Yang, Jung-Hee Kim
STUDY DESIGN: Retrospective analysis. OBJECTIVE: The object is to assess the correlation between whole lumbar lordosis (LL) and the segmental angle (SA) after single-level anterior lumbar interbody fusion for degenerative lumbar spondylolisthesis. SUMMARY OF BACKGROUND DATA: The restoration of the SA at lower lumbar spine is meaningful, considering it contributes approximately 60% of LL, and revision surgery due to flat back or adjacent segment pathology was necessary decades after the initial surgery...
August 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28746083/novel-cardiac-coordinate-modeling-system-for-three-dimensional-quantification-of-inflow-cannula-malposition-of-heartmate-ii-lvads
#17
Brian Lima, Onur Dur, Joyce Chuang, Themistokles Chamogeorgakis, David J Farrar, Kartik S Sundareswaran, Joost Felius, Susan M Joseph, Shelley A Hall, Gonzalo V Gonzalez-Stawinski
Optimal function of left ventricular assist devices (LVADs) depends on proper alignment of the inflow cannula (IC). Quantitative guidelines for IC angulation are lacking because of variation in cardiac geometry and difficulty in analyzing three-dimensional (3D) cannula orientation relative to the left ventricle (LV). Based on contrast-enhanced computed tomography images from five normal and five clinically malpositioned IC cases in patients with HeartMate II LVADs, we developed a method for 3D quantification of IC malpositioning...
July 25, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28746028/the-kaiser-permanente-northern-california-enhanced-recovery-after-surgery-program-design-development-and-implementation
#18
Vincent X Liu, Efren Rosas, Judith C Hwang, Eric Cain, Anne Foss-Durant, Molly Clopp, Mengfei Huang, Alexander Mustille, Vivian M Reyes, Shirley S Paulson, Michelle Caughey, Stephen Parodi
Complications are common after surgery, highlighting the need for innovations that reduce postsurgical morbidity and mortality. In this report, we describe the design, development, and implementation of an Enhanced Recovery After Surgery program in the Kaiser Permanente Northern California integrated health care delivery system. This program was implemented and disseminated in 2014, targeting patients who underwent elective colorectal resection and those who underwent emergent hip fracture repair across 20 Medical Centers...
2017: Permanente Journal
https://www.readbyqxmd.com/read/28745977/zap70-and-downstream-ranbp2-are-required-for-the-exact-timing-of-the-meiotic-cell-cycle-in-oocytes
#19
Hyun-Jung Kim, Su-Yeon Lee, Hyun-Seo Lee, Eun-Young Kim, Jung-Jae Ko, Kyung-Ah Lee
In previous studies, we observed that Zeta-chain-associated protein kinase 70 (Zap70) regulates spindle assembly and chromosome alignment in mouse oocyte and that Ran binding protein 2 (RanBP2) is highly associated gene with Zap70 based on a microarray analysis. Because RanBP2 is related to nuclear envelope breakdown (NEBD) during mitosis, the aim of the present study was to elucidate the molecular mechanism of Zap70 with respect to RanBP2 in the germinal vesicle breakdown (GVBD) of oocytes. Results indicated that RanBP2 expression was regulated by Zap70 and that depletion of RanBP2 using RanBP2 RNAi manifested comparable phenotypes to those observed in Zap70 RNAi-treated oocytes, which presented faster processing of GVBD...
July 26, 2017: Cell Cycle
https://www.readbyqxmd.com/read/28745761/study-of-the-simulated-sunlight-photolysis-mechanism-of-ketoprofen-the-role-of-superoxide-anion-radicals-transformation-byproducts-and-ecotoxicity-assessment
#20
Yingfei Wang, Wen Deng, Fengliang Wang, Yuehan Su, Yiping Feng, Ping Chen, Jingshuai Ma, Haiying Su, Kun Yao, Yang Liu, Wenying Lv, Guoguang Liu
The aim of this study was to investigate the photolysis mechanism of ketoprofen (KET) under simulated sunlight. The results demonstrated that the photolysis of KET aligned well with pseudo first-order kinetics. Radical scavenging experiments and dissolved oxygen experiments revealed that the superoxide anion radical (O2˙(-)) played a primary role in the photolytic process in pure water. Bicarbonate slightly increased the photodegradation of KET through generating carbonate radicals, while DOM inhibited the photolysis via both attenuating light and competing radicals...
July 26, 2017: Environmental Science. Processes & Impacts
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