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https://www.readbyqxmd.com/read/27906253/tunable-bloch-surface-waves-in-anisotropic-photonic-crystals-based-on-lithium-niobate-thin-films
#1
Tatiana Kovalevich, Abdoulaye Ndao, Miguel Suarez, Saulius Tumenas, Zigmas Balevicius, Arunas Ramanavicius, Ieva Baleviciute, Markus Häyrinen, Matthieu Roussey, Markku Kuittinen, Thierry Grosjean, Maria-Pilar Bernal
We present an original type of one-dimensional photonic crystal that includes one anisotropic layer made of a lithium niobate thin film. We demonstrate the versatility of such a device sustaining different Bloch surface waves (BSWs), depending on the orientation of the incident wave. By varying the orientation of the illumination of the multilayer, we measured an angle variation of 7° between the BSWs corresponding to the extraordinary and the ordinary index of the lithium niobate thin film. The potential of such a platform opens the way to novel tunable and active planar optics based on the electro- and thermo-optical properties of lithium niobate...
December 1, 2016: Optics Letters
https://www.readbyqxmd.com/read/27897254/high-level-expression-of-improved-thermo-stable-alkaline-xylanase-variant-in-pichia-pastoris-through-codon-optimization-multiple-gene-insertion-and-high-density-fermentation
#2
Yihong Lu, Cheng Fang, Qinhong Wang, Yuling Zhou, Guimin Zhang, Yanhe Ma
In paper industry, xylanases are used to increase the pulp properties in bleaching process as its eco-friendly nature. The xylanases activity is hindered by high temperature and alkaline conditions with high enzyme production cost in the paper industry. Here, XynHB, an alkaline stable xylanase from Bacillus pumilus HBP8 was mutated at N188A to XynHBN188A. Expressed mutant in E. coli showed 1.5-fold higher xylanase activity than XynHB at 60 °C. The mutant expressed in Pichia pastoris was glycosylated, remained stable for 30 min at 60 °C...
November 29, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27888253/thermo-sensitive-hydrogel-plga-peg-plga-as-a-vaccine-delivery-system-for-intramuscular-immunization
#3
Xiaoyan Wang, Yu Zhang, Wei Xue, Hong Wang, Xiaozhong Qiu, Zonghua Liu
In this work, we explored the potential of thermo-sensitive PLGA-PEG-PLGA with sol-gel transition temperature around 32℃ as an intramuscular vaccine delivery system by using ovalbumin as a model antigen. First, in vitro release test showed that the PLGA-PEG-PLGA-deriving hydrogels could release ovalbumin in vitro in a more sustainable way. From fluorescence living imaging, 50-200 mg/mL of PLGA-PEG-PLGA formulations could release antigen in a sustainable manner in vivo, suggesting that the PLGA-PEG-PLGA hydrogel worked as an antigen-depot...
November 25, 2016: Journal of Biomaterials Applications
https://www.readbyqxmd.com/read/27884748/isolation-of-bacterial-strains-able-to-degrade-biphenyl-diphenyl-ether-and-the-heat-transfer-fluid-used-in-thermo-solar-plants
#4
Rafael Blanco-Moreno, Lara P Sáez, Víctor M Luque-Almagro, M Dolores Roldán, Conrado Moreno-Vivián
Thermo-solar plants use eutectic mixtures of diphenyl ether (DE) and biphenyl (BP) as heat transfer fluid (HTF). Potential losses of HTF may contaminate soils and bioremediation is an attractive tool for its treatment. DE- or BP-degrading bacteria are known, but up to now bacteria able to degrade HTF mixture have not been described. Here, five bacterial strains which are able to grow with HTF or its separate components DE and BP as sole carbon sources have been isolated, either from soils exposed to HTF or from rhizospheric soils of plants growing near a thermo-solar plant...
November 21, 2016: New Biotechnology
https://www.readbyqxmd.com/read/27872009/molecular-details-on-gilthead-sea-bream-sparus-aurata-sensitivity-to-low-water-temperatures-from-1-h-nmr-metabolomics
#5
Riccardo Melis, Roberta Sanna, Angela Braca, Elia Bonaglini, Roberto Cappuccinelli, Hanno Slawski, Tonina Roggio, Sergio Uzzau, Roberto Anedda
Biometric and metabolic responses of gilthead sea bream to cold challenge are described following a growth trial divided into three water temperature steps, namely cooling, cold maintenance and recovery. Experimental data provide a useful description of fish response to thermal stress at both zootechnical and molecular level. Although no mortality has been observed, Nuclear Magnetic Resonance-based metabolomics confirms the marked sensitivity of this fish species to low water temperature, and explains some key molecular events associated to fish response to cold...
November 18, 2016: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
https://www.readbyqxmd.com/read/27862101/characterization-of-thermo-solvent-stable-protease-from-halobacillus-sp-cj4-isolated-from-chott-eldjerid-hypersaline-lake-in-tunisia
#6
Lobna Daoud, Mouna Jlidi, Houda Hmani, Adel Hadj Brahim, Mahdi El Arbi, Mamdouh Ben Ali
About 110 newly isolated halophilic and halotolerant bacteria were screened for protease production. A moderately halophilic strain (CJ4), isolated from Chott Eldjerid Hypersaline lake in Tunisia, showed the highest activity on agar plate and was then selected. The biochemical and physiological characterization of the isolate along with the 16S rRNA sequence analysis placed it in the genus Halobacillus. Protease production was maximal at 120 g/L NaCl (2 M) and it started from the post-exponential phase reaching a maximum level at the early decline phase of bacterial growth...
November 8, 2016: Journal of Basic Microbiology
https://www.readbyqxmd.com/read/27835772/characterization-of-three-autolysins-with-activity-against-cereulide-producing-bacillus-isolates-in-food-matrices
#7
Peiling Geng, Yimin Hu, Guoping Zhou, Zhiming Yuan, Xiaomin Hu
Bacillus cereus is a pathogen related with diarrhoeal or emetic food poisoning cases, of which the latter caused by the cereulide-producing isolates are more severe with several reported lethal cases. It is therefore necessary to develop an effective strategy to prevent the propagation of B. cereus in the food supply. In this study, three autolysins from the cereulide-producing B. cereus group isolates, LysIS075, LysF8819.1 and LysCER057, were identified and characterized. The results showed that the three autolysins were highly lytic and bactericidal to the tested cereulide-producing B...
October 26, 2016: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/27829203/precision-combination-therapy-for-triple-negative-breast-cancer-via-biomimetic-polydopamine-polymer-core-shell-nanostructures
#8
Yanping Ding, Shishuai Su, Ruirui Zhang, Leihou Shao, Yinlong Zhang, Bin Wang, Yiye Li, Long Chen, Qun Yu, Yan Wu, Guangjun Nie
Photothermal-based combination therapy using functional nanomaterials shows great promise in eradication of aggressive tumors and improvement of drug sensitivity. The therapeutic efficacy and adverse effects of drug combinations depend on the precise control of timely tumor-localized drug release. Here a polymer-dopamine nanocomposite is designed for combination therapy, thermo-responsive drug release and prevention of uncontrolled drug leakage. The thermo-sensitive co-polymer poly (2-(2-methoxyethoxy) ethyl methacrylate-co-oligo (ethylene glycol) methacrylate)-co-2-(dimethylamino) ethyl methacrylate-b-poly (D, l-lactide-co-glycolide) is constructed into core-shell structured nanoparticles for co-encapsulation of two cytotoxic drugs and absorption of small interfering RNAs against survivin...
November 2, 2016: Biomaterials
https://www.readbyqxmd.com/read/27792300/combining-two-photon-activated-fluorescence-resonance-energy-transfer-and-near-infrared-photothermal-effect-of-unimolecular-micelles-for-enhanced-photodynamic-therapy
#9
Yu Huang, Feng Qiu, Lingyue Shen, Dong Chen, Yue Su, Chao Yang, Bo Li, Deyue Yan, Xinyuan Zhu
Recent years have witnessed significant progress in the field of two-photon activated photodynamic therapy (2P-PDT). However, the traditional photosensitizer (PS) based 2P-PDT remains a critical challenge in clinics due to its low two-photon absorption (2PA) cross-sections. Here, we propose that the therapeutic activity of current PSs can be enhanced through a combination of two-photon excited fluorescence resonance energy transfer (FRET) strategy and photothermal effect of near infrared (NIR) light. A novel core-shell unimolecular micelle with large two-photon absorbing conjugated polymer core and thermo-responsive shell was constructed as a high two-photon light-harvesting material...
October 28, 2016: ACS Nano
https://www.readbyqxmd.com/read/27792001/angiogenic-potential-of-endothelial-and-tumor-cells-seeded-on-gelatin-based-hydrogels-in-response-to-electrical-stimulations
#10
Rumiana Tzoneva, Veselina Uzunova, Sonia Apostolova, Anne Krüger-Genge, Axel T Neffe, Friedrich Jung, Andreas Lendlein
Angiogenesis is one of the key processes during development, wound healing and tumor formation. Prerequisite for its existence is the presence of endogenous electrical fields (EFs) generated by active ion transport across polarized epithelia and endothelia, and appearance of the transcellular potentials. During angiogenesis cellular factor as endothelial growth factor (VEGF), synthesis of adhesive proteins and membrane metalloproteinases (MMPs) govern the angiogenic response to different external stimuli as biomaterials interactions and/or exogenous EF...
October 27, 2016: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/27789882/kinetic-characterization-thermo-stability-and-reactive-red-195a-dye-detoxifying-properties-of-manganese-peroxidase-coupled-gelatin-hydrogel
#11
Muhammad Bilal, Muhammad Asgher, Hongbo Hu, Xuehong Zhang
An indigenous and industrially important manganese peroxidase (MnP) was isolated from solid-state bio-processing of wheat bran by white-rot fungal strain Ganoderma lucidum IBL-05 under pre-optimized growth conditions. Crude MnP extract was partially purified (2.34-fold) to apparent homogeneity by ammonium sulphate precipitation and dialysis. The homogeneous enzyme preparation was encapsulated on gelatin matrix using glutaraldehyde as a cross-linking agent. Optimal conditions for highest immobilization (82.5%) were: gelatin 20% (w/v), glutaraldehyde 0...
October 2016: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/27788585/influence-of-the-production-process-on-the-key-aroma-compounds-of-rum-from-molasses-to-the-spirit
#12
Laura Franitza, Michael Granvogl, Peter Schieberle
The production of rum consists of fermentation, distillation, and ageing. To check the influence of each step on the final rum aroma, molasses, mash, distillate, and the final rum were analyzed using the sensomics concept. The changes in key aroma compounds were determined by application of aroma extract dilution analysis (AEDA) in combination with gas chromatography-mass spectrometry for identification and by stable isotope dilution assays (SIDAs) for quantitation. Odor activity values (OAVs; ratio of concentration to respective odor threshold) were calculated for the compounds determined in the rum and, finally, the rum aroma was successfully simulated by recombination...
October 27, 2016: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/27784260/sulfonated-polyimide-clay-thin-films-for-energy-application
#13
Farman Ali, Shaukat Saeed, Syed Sakhawat Shah, Fazal Rahim, Laurent Duclaux, Jean-Marc Levêque, Laurence Reinert
BACKGROUND: Sulfonated polyimides (SPIs) are considered as the promising alternatives to Nafion as membrane materials for the polymer electrolyte membrane (PEM). They generally exhibit high ionic conductivity, good mechanical properties, excellent thermal and chemical stabilities. The six-membered ring, naphthalenic anhydride-based SPIs, not only exhibit superior chemical and thermo-oxidative stabilities but are also more resistant to hydrolysis than their five-membered phthalic anhydride-based SPIs...
October 25, 2016: Recent Patents on Nanotechnology
https://www.readbyqxmd.com/read/27775202/highly-swellable-dual-responsive-hydrogels-based-on-pnipam-and-redox-active-poly-ferrocenylsilane-poly-ionic-liquid-s-synthesis-structure-and-properties
#14
Xueling Feng, Kaihuan Zhang, Peng Chen, Xiaofeng Sui, Mark A Hempenius, Bo Liedberg, G Julius Vancso
Highly swellable, dual-responsive hydrogels, consisting of thermo-responsive poly(N-isopropylacrylamide) (PNIPAM) and redox-responsive poly(ferrocenylsilane) (PFS) based poly(ionic liquid)s (PILs) are formed by photo-polymerization. PFS chains bearing cross-linkable vinylimidazolium (VIm) side groups are copolymerized with NIPAM in aqueous solutions under ultraviolet light (λ = 365 nm) in the presence of a photoinitiator. The PFS-PILs serve as a macro-cross-linker and also provide redox responsiveness. The swelling ratio, morphology, and lower critical solution temperature (LCST) of the hydrogels are studied as a function of the PNIPAM/PFS ratio...
December 2016: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/27757589/trp-channels-potential-drug-target-for-neuropathic-pain
#15
Lovish Marwaha, Yashika Bansal, Raghunath Singh, Priyanka Saroj, Ranjana Bhandari, Anurag Kuhad
Neuropathic pain is a debilitating disease which affects central as well as peripheral nervous system. Transient receptor potential (TRP) channels are ligand-gated ion channels that detect physical and chemical stimuli and promote painful sensations via nociceptor activation. TRP channels have physiological role in the mechanisms controlling several physiological responses like temperature and mechanical sensations, response to painful stimuli, taste, and pheromones. TRP channel family involves six different TRPs (TRPV1, TRPV2, TRPV3, TRPV4, TRPM8, and TRPA1) which are expressed in pain sensing neurons and primary afferent nociceptors...
October 18, 2016: Inflammopharmacology
https://www.readbyqxmd.com/read/27755345/human-milk-processing-a-systematic-review-of-innovative-techniques-to-the-ensure-safety-and-quality-of-donor-milk
#16
Chiara Peila, Nikki E Emmerik, Marzia Giribaldi, Bernd Stahl, Joost E Ruitenberg, Ruurd M van Elburg, Guido E Moro, Enrico Bertino, Alessandra Coscia, Laura Cavallarin
OBJECTIVES: Pasteurization, performed at 62.5°C for 30 min (holder pasteurization), is currently recommended in all international human milk banks guidelines, but it affects some human milk bioactive and nutritive components. The present systematic review is aimed at critically reviewing evidence on the suitability of human milk processing techniques other than holder pasteurization, both thermal and non-thermal, to ensure microbiological safety, and on the effects of these techniques on biologically active donor milk components...
October 13, 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27747303/non-isothermal-kinetic-study-of-de-oiled-seeds-cake-of-african-star-apple-chrosophyllum-albidum-using-thermogravimetry
#17
M A Sokoto, Rawel Singh, Bhavya B Krishna, Jitendra Kumar, Thallada Bhaskar
Thermal decomposition and kinetics behaviour of the de-oiled seed cake of African star apple (Chrosophyllum albidum) has been investigated using thermogravimetry under the nitrogen atmosphere from ambient temperature to 900 °C. The thermogravimetric data for the cake decomposition at six different heating rates (5, 10, 15, 20, 30 and 40 °C/min) were used to evaluate the kinetic decomposition of the cake using Friedman (FD), Kissinger-Akahira-Sunose (KAS) and Flynn-Wall-Ozawa (FWO) models. Thermal decomposition of the cake showed thermograms indicating dehydration and devolitilization stages (200-400 °C)...
October 2016: Heliyon
https://www.readbyqxmd.com/read/27737605/production-characterization-and-immobilization-of-partially-purified-surfactant-detergent-and-alkali-thermo-stable-protease-from-newly-isolated-aeromonas-caviae
#18
Sumitra Datta, Gopalakrishnan Menon, Bincy Varughese
Proteolytic Aeromonas caviae P-1-1 growing at wide ranging pH (7.0-11.0) and moderate salinity (0-5% NaCl) was isolated from cattle-shed of Thanjavur, India. It produced lipase, gelatinase and polyhydroxybutyrate. Different culture conditions, incubation time, carbon and nitrogen sources, vitamins, amino acids, surfactants and metal ions for optimal growth and protease production of P-1-1 were examined. Maximum protease (0.128 U/mL) production was achieved with 1% fructose, 1% yeast extract, 0.1% ammonium sulfate, 3% NaCl, 0...
October 13, 2016: Preparative Biochemistry & Biotechnology
https://www.readbyqxmd.com/read/27733934/model-assessing-thermal-changes-during-high-temperature-root-canal-irrigation
#19
Analise Bartolo, Edmond Koyess, Josette Camilleri, Christopher Micallef
The main aim of root canal irrigation is to eliminate micro-organisms. Sodium hypochlorite (NaOCl) is considered to be the ideal material and raising its temperature potentiates the antimicrobial activity. NaOCl may lead to localised tissue necrosis when extruded past the root apex. This study analyses the use of high temperature root canal irrigation as an alternative process for the elimination of microorganisms from the root canal system. An experimental set-up was designed where a constant supply of heat was passed from a heat source through a copper wire inside the root canal...
September 2016: Healthcare Technology Letters
https://www.readbyqxmd.com/read/27731314/nicotinamide-is-an-endogenous-agonist-for-a-c-elegans-trpv-osm-9-and-ocr-4-channel
#20
Awani Upadhyay, Aditya Pisupati, Timothy Jegla, Matt Crook, Keith J Mickolajczyk, Matthew Shorey, Laura E Rohan, Katherine A Billings, Melissa M Rolls, William O Hancock, Wendy Hanna-Rose
TRPV ion channels are directly activated by sensory stimuli and participate in thermo-, mechano- and chemo-sensation. They are also hypothesized to respond to endogenous agonists that would modulate sensory responses. Here, we show that the nicotinamide (NAM) form of vitamin B3 is an agonist of a Caenorhabditis elegans TRPV channel. Using heterologous expression in Xenopus oocytes, we demonstrate that NAM is a soluble agonist for a channel consisting of the well-studied OSM-9 TRPV subunit and relatively uncharacterized OCR-4 TRPV subunit as well as the orthologous Drosophila Nan-Iav TRPV channel, and we examine stoichiometry of subunit assembly...
October 12, 2016: Nature Communications
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