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https://www.readbyqxmd.com/read/29040611/association-between-pre-pregnancy-overweight-and-obesity-and-children-s-neurocognitive-development-a-systematic-review-and-meta-analysis-of-observational-studies
#1
Celia Álvarez-Bueno, Ivan Cavero-Redondo, Lidia Lucas-de la Cruz, Blanca Notario-Pacheco, Vicente Martínez-Vizcaíno
Background: Obesity and overweight during pregnancy have been negatively associated with fetal and offspring neurodevelopment. The aim of this systematic review and meta-analysis was to assess the effect of the relationship between pre-pregnancy overweight and obesity with children's neurocognitive development. Methods: We systematically searched MEDLINE, EMBASE, the Cochrane Library and the Web of Science databases from their inception through February 2017 for follow-up studies comparing the relationship between pre-pregnancy weight status and children's cognition...
July 13, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29040540/new-debate-is-it-time-for-infertility-weight-loss-programmes-to-be-couple-based
#2
Damian Best, Alison Avenell, Siladitya Bhattacharya, Gertraud Stadler
With obesity on the rise in the general population, it has also become more prevalent among people of reproductive age. Weight loss has shown benefits in overweight women and men experiencing fertility problems. However, the existing weight-loss interventions for individuals with infertility are associated with high drop-out rates and limited success. In this article, we argue for the development of weight-loss programmes targeting couples, as couples are routinely seen in fertility clinics, rather than individuals...
October 12, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29040334/advanced-maternal-age-and-adverse-pregnancy-outcomes-a-systematic-review-and-meta-analysis
#3
Samantha C Lean, Hayley Derricott, Rebecca L Jones, Alexander E P Heazell
BACKGROUND: Advanced maternal age (AMA; ≥35 years) is an increasing trend and is reported to be associated with various pregnancy complications. OBJECTIVE: To determine the risk of stillbirth and other adverse pregnancy outcomes in women of AMA. SEARCH STRATEGY: Embase, Medline (Ovid), Cochrane Database of Systematic Reviews, ClinicalTrials.gov, LILACS and conference proceedings were searched from ≥2000. SELECTION CRITERIA: Cohort and case-control studies reporting data on one or more co-primary outcomes (stillbirth or fetal growth restriction (FGR)) and/or secondary outcomes in mothers ≥35 years and <35 years...
2017: PloS One
https://www.readbyqxmd.com/read/29034545/a-pilot-intervention-to-reduce-postpartum-weight-retention-and-central-adiposity-in-first-time-mothers-results-from-the-mums-online-online-lifestyle-nutrition-exercise-study
#4
P van der Pligt, K Ball, K D Hesketh, M Teychenne, D Crawford, P J Morgan, C E Collins, K J Campbell
BACKGROUND: Postpartum weight retention (PPWR) increases the risk for obesity and complications during subsequent pregnancies. Few interventions have been successful in limiting PPWR in mothers. The present study assessed the effectiveness of the mums OnLiNE (Online, Lifestyle, Nutrition & Exercise) intervention with respect to reducing PPWR and improving diet, physical activity and sedentary behaviour. METHODS: A subsample of first-time mothers enrolled in the Extended Melbourne Infant Feeding Activity and Nutrition Trial (InFANT Extend) completed the nonrandomised mums OnLiNE intervention...
October 16, 2017: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
https://www.readbyqxmd.com/read/29034064/personalized-therapy-against-preeclampsia-by-replenishing-placental-protein-13-pp13-targeted-to-patients-with-impaired-pp13-molecule-or-function
#5
REVIEW
Hamutal Meiri, George Osol, Irene Cetin, Sveinbjörn Gizurarson, Berthold Huppertz
Hypertensive disorders affect about one third of all people aged 20 and above, and are treated with anti-hypertensive drugs. Preeclampsia (PE) is one form of such disorders that only develops during pregnancy. It affects ten million pregnant women globally and additionally causes fetal loss and major newborn disabilities. The syndrome's origin is multifactorial, and anti-hypertensive drugs are ineffective in treating it. Biomarkers are helpful for predict its development. Generic drugs, such as low dose aspirin, were proven effective in preventing preterm PE...
2017: Computational and Structural Biotechnology Journal
https://www.readbyqxmd.com/read/29033897/evaluation-of-cardiometabolic-parameters-among-obese-women-using-oral-contraceptives
#6
Júnia Raquel Dutra Ferreira, Milena Magalhães Aleluia, Camylla Vilas Boas Figueiredo, Larissa Castro de Lima Vieira, Rayra Pereira Santiago, Caroline Conceição da Guarda, Cynara Gomes Barbosa, Ricardo Riccio Oliveira, Elisângela Vitória Adorno, Marilda de Souza Gonçalves
BACKGROUND: Combined oral contraceptive (COC) use has been associated with an unfavorable impact on carbohydrate and lipid metabolism in diverse populations of normal weight and obese women. The present study aimed to evaluate the cardiometabolic and inflammatory profiles of women in northeastern Brazil with respect to COC use and obesity. METHODS: We performed a cross-sectional study to verify cardiovascular parameters, including blood pressure (BP), fasting serum glucose, lipid, and inflammatory profile, in a population of women aged 15-45 years, considering obesity and COC use...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29033611/stable-ischemic-heart-disease-in-women-current-perspectives
#7
REVIEW
Fatima Samad, Anushree Agarwal, Zainab Samad
Cardiovascular disease is the leading cause of death in women accounting for 1 in every 4 female deaths. Pathophysiology of ischemic heart disease in women includes epicardial coronary artery, endothelial dysfunction, coronary vasospasm, plaque erosion and spontaneous coronary artery dissection. Angina is the most common presentation of stable ischemic heart disease (SIHD) in women. Risk factors for SIHD include traditional risks such as older age, obesity (body mass index [BMI] >25 kg/m(2)), smoking, hypertension, dyslipidemia, cerebrovascular and peripheral vascular disease, sedentary lifestyle, family history of premature coronary artery disease, metabolic syndrome and diabetes mellitus, and nontraditional risk factors, such as gestational diabetes, insulin resistance/polycystic ovarian disease, pregnancy-induced hypertension, pre-eclampsia, eclampsia, menopause, mental stress and autoimmune diseases...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/29031756/obstructive-sleep-apnea-in-pregnancy-is-associated-with-adverse-maternal-outcomes-a-national-cohort
#8
Ghada Bourjeily, Valery A Danilack, Margaret H Bublitz, Heather Lipkind, Janet Muri, Donna Caldwell, Iris Tong, Karen Rosene-Montella
OBJECTIVE: Pregnancy and the obesity epidemic impacting women of reproductive age appear to predispose women to obstructive sleep apnea (OSA) in pregnancy. The aim of this study is to examine the association between OSA and adverse maternal outcomes in a national cohort. METHODS: The National Perinatal Information Center in the US was used to identify women with a delivery discharge diagnosis of OSA from 2010 to 2014. We used the International Classification of Diseases, ninth Revision to classify OSA diagnosis and maternal outcomes...
October 2017: Sleep Medicine
https://www.readbyqxmd.com/read/29027317/exposure-to-omentum-adipose-tissue-conditioned-medium-from-obese-pregnant-women-promotes-myometrial-artery-dysfunction
#9
Christina E Hayward, Elizabeth J Cowley, Colin P Sibley, Jenny E Myers, Mark Wareing
AIM: Underlying mechanisms of poor pregnancy outcome in obese (OB) mothers (body mass index [BMI] ≥ 30 kg/m(2) ) are unknown. Our studies demonstrate that OB pregnant women have altered myometrial artery (MA) function related to the thromboxane and nitric oxide pathways. In obesity, increased central fat mass is associated with an altered endocrine milieu. We tested the hypothesis that in OB pregnant women the omentum, a central fat store, releases factors that promote dysfunction in normal MAs...
October 13, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29027303/increased-maternal-insulin-resistance-promotes-placental-growth-and-decreases-placental-efficiency-in-pregnancies-with-obesity-and-gestational-diabetes-mellitus
#10
Kei Tanaka, Kenji Yamada, Miho Matsushima, Tomoko Izawa, Seishi Furukawa, Yoichi Kobayashi, Mitsutoshi Iwashita
AIM: Homeostasis model assessment for insulin resistance (HOMA-IR) was measured during pregnancy to analyze placental weight and efficiency in relation to maternal insulin resistance. METHODS: A retrospective study of 510 pregnant women (130 with gestational diabetes mellitus [GDM], 380 with normal glucose tolerance) was conducted. We reviewed the patients' demographic data (age, parity, pre-pregnancy body mass index [BMI]) and perinatal outcomes (birth weight, placental weight, BMI at delivery, maternal weight gain, HOMA-IR)...
October 13, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29026373/how-weight-during-pregnancy-influences-the-association-between-pre-pregnancy-body-mass-index-and-types-of-delivery-and-birth-a-comparison-of-urban-and-rural-areas
#11
Manoochehr Babanezhad
BACKGROUND: Women in study areas suffered from the problems of caesarean delivery (CD), low birth weight (LBW), and macrosomia. OBJECTIVE: To investigate how gestational weight gain (GWG) influences the effect of the pre-pregnancy body mass index (BMI) on the risks of CD, LBW, and macrosomia in urban and rural areas in a city of Iran. METHODS: We used 767 and 612 eligible subjects from the public health care centers in urban and rural areas respectively...
March 2017: African Health Sciences
https://www.readbyqxmd.com/read/29026216/associations-of-maternal-and-cord-blood-adipokines-with-offspring-adiposity-in-project-viva-is-there-an-interaction-with-child-age
#12
L-J Li, S L Rifas-Shiman, I M Aris, J G Young, C Mantzoros, M-F Hivert, E Oken
OBJECTIVES: Higher leptin and lower adiponectin correlate with adult and childhood adiposity, but it is unclear how exposure to these adipokines during gestation relates to offspring growth. We aimed to investigate the relationships of maternal and cord adipokines with offspring adiposity across childhood to early adolescence, as well as interactions with child age. METHODS: In mother-child pairs in the Project Viva cohort, we measured adipokines in mothers at 2nd trimester (n=1106) and in cord blood at birth (n=657)...
October 13, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29025451/mid-upper-arm-circumference-a-surrogate-for-body-mass-index-in-pregnant-women
#13
Ahminah Fakier, Gregory Petro, S Fawcus
BACKGROUND: Nutrition in pregnancy has implications for both mother and fetus, hence the importance of an accurate assessment at the booking visit during antenatal care. The body mass index (BMI, kg/m2) is currently the gold standard for measuring body fatness. However, pregnancy-associated weight gain and oedema, as well as late booking in our population setting, cause concern about the reliability of using the BMI to assess body fat or nutritional status in pregnancy. The mid-upper arm circumference (MUAC) has been used for many decades to assess malnutrition in children aged <5 years...
June 30, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/29024991/association-between-pre-pregnancy-overweight-and-obesity-and-children-s-neurocognitive-development-a-systematic-review-and-meta-analysis-of-observational-studies
#14
Celia Álvarez-Bueno, Ivan Cavero-Redondo, Lidia Lucas-de la Cruz, Blanca Notario-Pacheco, Vicente Martínez-Vizcaíno
No abstract text is available yet for this article.
August 8, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29024955/offspring-risk-of-obesity-in-childhood-adolescence-and-adulthood-in-relation-to-gestational-diabetes-mellitus-a-sex-specific-association
#15
Shanshan Li, Yeyi Zhu, Edwina Yeung, Jorge E Chavarro, Changzheng Yuan, Alison E Field, Stacey A Missmer, James L Mills, Frank B Hu, Cuilin Zhang
Background: Animal data suggest sexually dimorphic programming of obesity in response to altered intrauterine environment, but the longitudinal impact of gestational diabetes mellitus (GDM) on sex-specific risk of offspring obesity in humans is unclear. Methods: We conducted a prospective analysis of 15 009 US individuals (7946 female and 7063 male) from the Growing-Up Today Study, who were followed from 1996 (ages 9-14 years) through 2010. Height and weight from validated questionnaires were used to derive body mass index (BMI) at different ages...
August 9, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29022513/discrepancies-in-animal-models-of-preterm-birth
#16
Clarence R Manuel, Charles R Ashby, Sandra E Reznik
BACKGROUND: Preterm birth (PTB) is a multifactorial syndrome occurring before the 37th week of full-term pregnancy [1]. Babies delivered preterm experience short-term and long-term complications affecting multiple organ systems, and serious maternal complications include hemorrhage and infection. Each year, an estimated 15 million babies are born preterm, and complications from prematurity are the leading cause of death among children up to 5 years of age [2]. With another increase in PTB rates over the last several years, the United States continues to have the highest incidence of any industrialized country [3]...
October 12, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29021781/cross-talk-between-adipose-tissue-and-placenta-in-obese-and-gestational-diabetes-mellitus-pregnancies-via-exosomes
#17
REVIEW
Nanthini Jayabalan, Soumyalekshmi Nair, Zarin Nuzhat, Gregory E Rice, Felipe A Zuñiga, Luis Sobrevia, Andrea Leiva, Carlos Sanhueza, Jaime Agustín Gutiérrez, Martha Lappas, Dilys Jane Freeman, Carlos Salomon
Obesity is an important public health issue worldwide, where it is commonly associated with the development of metabolic disorders, especially insulin resistance (IR). Maternal obesity is associated with an increased risk of pregnancy complications, especially gestational diabetes mellitus (GDM). Metabolism is a vital process for energy production and the maintenance of essential cellular functions. Excess energy storage is predominantly regulated by the adipose tissue. Primarily made up of adipocytes, adipose tissue acts as the body's major energy reservoir...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29020931/weight-management-during-pregnancy-a-qualitative-study-of-women-s-and-care-providers-experiences-and-perspectives
#18
Sara Holton, Christine East, Jane Fisher
BACKGROUND: Obesity during pregnancy is a serious health problem for women and their children. Despite the high prevalence of high body mass index (BMI) among women of reproductive age in high-income countries, there is insufficient evidence to inform practice and policy about weight management for women with high BMI who are pregnant. The aim of this project was to describe women's and midwives' experiences and perspectives of care for weight management during pregnancy in Melbourne, Australia...
October 11, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29016858/maternal-bmi-at-the-start-of-pregnancy-and-offspring-epigenome-wide-dna-methylation-findings-from-the-pregnancy-and-childhood-epigenetics-pace-consortium
#19
Gemma C Sharp, Lucas A Salas, Claire Monnereau, Catherine Allard, Paul Yousefi, Todd M Everson, Jon Bohlin, Zongli Xu, Rae-Chi Huang, Sarah E Reese, Cheng-Jian Xu, Nour Baïz, Cathrine Hoyo, Golareh Agha, Ritu Roy, John W Holloway, Akram Ghantous, Simon K Merid, Kelly M Bakulski, Leanne K Küpers, Hongmei Zhang, Rebecca C Richmond, Christian M Page, Liesbeth Duijts, Rolv T Lie, Phillip E Melton, Judith M Vonk, Ellen A Nohr, ClarLynda Williams-DeVane, Karen Huen, Sheryl L Rifas-Shiman, Carlos Ruiz-Arenas, Semira Gonseth, Faisal I Rezwan, Zdenko Herceg, Sandra Ekström, Lisa Croen, Fahimeh Falahi, Patrice Perron, Margaret R Karagas, Bilal M Quraishi, Matthew Suderman, Maria C Magnus, Vincent W V Jaddoe, Jack A Taylor, Denise Anderson, Shanshan Zhao, Henriette A Smit, Michele J Josey, Asa Bradman, Andrea A Baccarelli, Mariona Bustamante, Siri E Håberg, Göran Pershagen, Irva Hertz-Picciotto, Craig Newschaffer, Eva Corpeleijn, Luigi Bouchard, Debbie A Lawlor, Rachel L Maguire, Lisa F Barcellos, George Davey Smith, Brenda Eskenazi, Wilfried Karmaus, Carmen J Marsit, Marie-France Hivert, Harold Snieder, M Daniele Fallin, Erik Melén, Monica C Munthe-Kaas, Hasan Arshad, Joseph L Wiemels, Isabella Annesi-Maesano, Martine Vrijheid, Emily Oken, Nina Holland, Susan K Murphy, Thorkild I A Sørensen, Gerard H Koppelman, John P Newnham, Allen J Wilcox, Wenche Nystad, Stephanie J London, Janine F Felix, Caroline L Relton
Pre-pregnancy maternal obesity is associated with adverse offspring outcomes at birth and later in life. Individual studies have shown that epigenetic modifications such as DNA methylation could contribute. Within the Pregnancy and Childhood Epigenetics (PACE) Consortium, we meta-analysed the association between pre-pregnancy maternal BMI and methylation at over 450,000 sites in newborn blood DNA, across 19 cohorts (9,340 mother-newborn pairs). We attempted to infer causality by comparing the effects of maternal versus paternal BMI and incorporating genetic variation...
October 15, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/29016493/early-pregnancy-diabetes-screening-and-diagnosis-prevalence-rates-of-abnormal-test-results-and-associated-factors
#20
John F Mission, Janet Catov, Tiffany E Deihl, Maisa Feghali, Christina Scifres
OBJECTIVE: To evaluate the prevalence of early diabetes screening in pregnancy, rates of abnormal diabetes test results before 24 weeks of gestation, and factors associated with early diabetes screening. METHODS: This was a retrospective cohort study of all singleton deliveries from 2012 to 2014 among diverse clinical practices at a large academic medical center. We assessed rates of early (less than 24 weeks of gestation) and routine (at or beyond 24 weeks of gestation) diabetes screening, with abnormal test results defined using the Carpenter-Coustan criteria, a 50-g glucose challenge test result greater than 200 mg/dL, or a hemoglobin A1C level greater than 6...
October 6, 2017: Obstetrics and Gynecology
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